| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | fibroblast growth factor receptor activity | 1.27e-04 | 5 | 72 | 2 | GO:0005007 | |
| Domain | TMEM183 | 1.38e-05 | 2 | 70 | 2 | IPR026509 | |
| Domain | FGF_rcpt_fam | 8.27e-05 | 4 | 70 | 2 | IPR016248 | |
| Domain | DOCK_C | 7.45e-04 | 11 | 70 | 2 | IPR010703 | |
| Domain | DHR-1_domain | 7.45e-04 | 11 | 70 | 2 | IPR027007 | |
| Domain | DHR_2 | 7.45e-04 | 11 | 70 | 2 | PS51651 | |
| Domain | DHR_1 | 7.45e-04 | 11 | 70 | 2 | PS51650 | |
| Domain | DOCK-C2 | 7.45e-04 | 11 | 70 | 2 | PF14429 | |
| Domain | DHR-2 | 7.45e-04 | 11 | 70 | 2 | IPR027357 | |
| Domain | DHR-2 | 7.45e-04 | 11 | 70 | 2 | PF06920 | |
| Domain | DOCK | 7.45e-04 | 11 | 70 | 2 | IPR026791 | |
| Domain | UIM | 3.62e-03 | 24 | 70 | 2 | PS50330 | |
| Domain | UIM_dom | 3.93e-03 | 25 | 70 | 2 | IPR003903 | |
| Domain | TyrKc | 4.41e-03 | 88 | 70 | 3 | SM00219 | |
| Domain | Tyr_kinase_cat_dom | 4.41e-03 | 88 | 70 | 3 | IPR020635 | |
| Pubmed | A dual-activity topoisomerase complex regulates mRNA translation and turnover. | TYK2 GDPD5 CRYBG2 RPAP1 FNTB PTPRS NBEAL2 ZDHHC5 REV3L CAMSAP1 DOCK6 REXO1 MED12 ELL | 7.60e-08 | 1105 | 74 | 14 | 35748872 |
| Pubmed | Putative tyrosine kinases expressed in K-562 human leukemia cells. | 3.22e-07 | 7 | 74 | 3 | 2247464 | |
| Pubmed | 5.14e-07 | 8 | 74 | 3 | 7657660 | ||
| Pubmed | 7.70e-07 | 9 | 74 | 3 | 12817007 | ||
| Pubmed | A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma. | 1.10e-06 | 10 | 74 | 3 | 7690989 | |
| Pubmed | Protein kinase Cdelta regulates apoptosis via activation of STAT1. | 1.51e-06 | 11 | 74 | 3 | 15322115 | |
| Pubmed | 1.51e-06 | 11 | 74 | 3 | 7543024 | ||
| Pubmed | Transformation and Stat activation by derivatives of FGFR1, FGFR3, and FGFR4. | 2.01e-06 | 12 | 74 | 3 | 10918587 | |
| Pubmed | 2.01e-06 | 12 | 74 | 3 | 12637327 | ||
| Pubmed | 4.13e-06 | 15 | 74 | 3 | 11839738 | ||
| Pubmed | Origination and evolution of a human-specific transmembrane protein gene, c1orf37-dup. | 4.47e-06 | 2 | 74 | 2 | 16644869 | |
| Pubmed | FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung. | 4.47e-06 | 2 | 74 | 2 | 9716527 | |
| Pubmed | 4.47e-06 | 2 | 74 | 2 | 20093646 | ||
| Pubmed | 4.47e-06 | 2 | 74 | 2 | 26431494 | ||
| Pubmed | 4.47e-06 | 2 | 74 | 2 | 17957151 | ||
| Pubmed | 4.47e-06 | 2 | 74 | 2 | 11731410 | ||
| Pubmed | 5.75e-06 | 119 | 74 | 5 | 23508102 | ||
| Pubmed | The cell surface receptor FGFRL1 forms constitutive dimers that promote cell adhesion. | 1.34e-05 | 3 | 74 | 2 | 18061161 | |
| Pubmed | Compound deletion of Fgfr3 and Fgfr4 partially rescues the Hyp mouse phenotype. | 1.34e-05 | 3 | 74 | 2 | 21139072 | |
| Pubmed | 1.34e-05 | 3 | 74 | 2 | 21561999 | ||
| Pubmed | 1.34e-05 | 3 | 74 | 2 | 8083748 | ||
| Pubmed | 1.70e-05 | 529 | 74 | 8 | 14621295 | ||
| Pubmed | 2.06e-05 | 25 | 74 | 3 | 11294897 | ||
| Pubmed | 2.67e-05 | 4 | 74 | 2 | 9664689 | ||
| Pubmed | 2.67e-05 | 4 | 74 | 2 | 18677770 | ||
| Pubmed | 2.67e-05 | 4 | 74 | 2 | 9212826 | ||
| Pubmed | 2.67e-05 | 4 | 74 | 2 | 27154171 | ||
| Pubmed | Amplification of FRS2 and activation of FGFR/FRS2 signaling pathway in high-grade liposarcoma. | 2.67e-05 | 4 | 74 | 2 | 23393200 | |
| Pubmed | Immunolocalization of fibroblast growth factor receptors in normal and wounded human skin. | 2.67e-05 | 4 | 74 | 2 | 12373339 | |
| Pubmed | FGFR1-4 RNA-Based Gene Alteration and Expression Analysis in Squamous Non-Small Cell Lung Cancer. | 2.67e-05 | 4 | 74 | 2 | 36142417 | |
| Pubmed | 2.67e-05 | 4 | 74 | 2 | 11759058 | ||
| Pubmed | The FGF system has a key role in regulating vascular integrity. | 2.67e-05 | 4 | 74 | 2 | 18776942 | |
| Pubmed | RNAi-based conditional gene knockdown in mice using a U6 promoter driven vector. | 2.67e-05 | 4 | 74 | 2 | 17304337 | |
| Pubmed | 2.67e-05 | 4 | 74 | 2 | 16210019 | ||
| Pubmed | 2.67e-05 | 4 | 74 | 2 | 12644244 | ||
| Pubmed | 4.45e-05 | 5 | 74 | 2 | 27206683 | ||
| Pubmed | Conditional knockdown of Fgfr2 in mice using Cre-LoxP induced RNA interference. | 4.45e-05 | 5 | 74 | 2 | 15987787 | |
| Pubmed | The expression profiles of fibroblast growth factor 9 and its receptors in developing mice testes. | 4.45e-05 | 5 | 74 | 2 | 27078042 | |
| Pubmed | Different intracellular trafficking of FGF1 endocytosed by the four homologous FGF receptors. | 4.45e-05 | 5 | 74 | 2 | 16091423 | |
| Pubmed | FGF-dependent regulation of VEGF receptor 2 expression in mice. | 4.45e-05 | 5 | 74 | 2 | 21633168 | |
| Pubmed | Expression of fibroblast growth factor receptors in peri-implantation mouse embryos. | 4.45e-05 | 5 | 74 | 2 | 9771645 | |
| Pubmed | 4.45e-05 | 5 | 74 | 2 | 29122839 | ||
| Pubmed | 4.45e-05 | 5 | 74 | 2 | 28094278 | ||
| Pubmed | 4.45e-05 | 5 | 74 | 2 | 9013630 | ||
| Pubmed | The mouse Fgfrl1 gene coding for a novel FGF receptor-like protein. | 4.45e-05 | 5 | 74 | 2 | 11566361 | |
| Pubmed | 6.66e-05 | 6 | 74 | 2 | 10572038 | ||
| Pubmed | 6.66e-05 | 6 | 74 | 2 | 9010207 | ||
| Pubmed | 6.66e-05 | 6 | 74 | 2 | 16365308 | ||
| Pubmed | 6.66e-05 | 6 | 74 | 2 | 18753255 | ||
| Pubmed | Regulation of fibroblast growth factor-23 signaling by klotho. | 6.66e-05 | 6 | 74 | 2 | 16436388 | |
| Pubmed | 6.66e-05 | 6 | 74 | 2 | 19232523 | ||
| Pubmed | 6.66e-05 | 6 | 74 | 2 | 19966287 | ||
| Pubmed | 6.66e-05 | 6 | 74 | 2 | 29720668 | ||
| Pubmed | 6.66e-05 | 6 | 74 | 2 | 19515808 | ||
| Pubmed | Evidence that the novel receptor FGFRL1 signals indirectly via FGFR1. | 6.66e-05 | 6 | 74 | 2 | 24026051 | |
| Pubmed | ATAC and Mediator coactivators form a stable complex and regulate a set of non-coding RNA genes. | 8.26e-05 | 107 | 74 | 4 | 20508642 | |
| Pubmed | Dominant negative stat3 mutant inhibits interleukin-6-induced Jak-STAT signal transduction. | 9.31e-05 | 7 | 74 | 2 | 8626374 | |
| Pubmed | 9.31e-05 | 7 | 74 | 2 | 16772167 | ||
| Pubmed | 9.31e-05 | 7 | 74 | 2 | 8959336 | ||
| Pubmed | Expression patterns of FGF receptors in the developing mammalian cochlea. | 9.31e-05 | 7 | 74 | 2 | 20131355 | |
| Pubmed | ErbB-2 activates Stat3 alpha in a Src- and JAK2-dependent manner. | 1.24e-04 | 8 | 74 | 2 | 11940572 | |
| Pubmed | 1.24e-04 | 8 | 74 | 2 | 18187602 | ||
| Pubmed | 1.24e-04 | 8 | 74 | 2 | 17623664 | ||
| Pubmed | Syndecan-4 dependent FGF stimulation of mouse vibrissae growth. | 1.24e-04 | 8 | 74 | 2 | 16989989 | |
| Pubmed | Expression of Fgf receptors 1, 2, and 3 in the developing mid- and hindbrain of the mouse. | 1.59e-04 | 9 | 74 | 2 | 15830353 | |
| Pubmed | Dynamic activation of Wnt, Fgf, and Hh signaling during soft palate development. | 1.59e-04 | 9 | 74 | 2 | 31613912 | |
| Pubmed | Integration of FGF and TWIST in calvarial bone and suture development. | 1.59e-04 | 9 | 74 | 2 | 10751173 | |
| Pubmed | 1.59e-04 | 9 | 74 | 2 | 11335076 | ||
| Pubmed | 1.59e-04 | 9 | 74 | 2 | 15229180 | ||
| Pubmed | Hypertonicity activates Na+/H+ exchange through Janus kinase 2 and calmodulin. | 1.59e-04 | 9 | 74 | 2 | 12626508 | |
| Pubmed | Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. | 1.79e-04 | 51 | 74 | 3 | 15963767 | |
| Pubmed | 1.99e-04 | 10 | 74 | 2 | 15470137 | ||
| Pubmed | Regulation of external genitalia development by concerted actions of FGF ligands and FGF receptors. | 1.99e-04 | 10 | 74 | 2 | 15340846 | |
| Pubmed | Activation of STAT3 by the Src family kinase Hck requires a functional SH3 domain. | 1.99e-04 | 10 | 74 | 2 | 12244095 | |
| Pubmed | 2.43e-04 | 11 | 74 | 2 | 8901049 | ||
| Pubmed | Fgf20 is required for sensory epithelial specification in the developing cochlea. | 2.43e-04 | 11 | 74 | 2 | 18524904 | |
| Pubmed | 2.43e-04 | 11 | 74 | 2 | 26906157 | ||
| Pubmed | The murine gene, Traube, is essential for the growth of preimplantation embryos. | 2.43e-04 | 11 | 74 | 2 | 11071758 | |
| Pubmed | 2.43e-04 | 11 | 74 | 2 | 20471949 | ||
| Pubmed | Immunohistochemical study of genesis of the mouse oral vestibule. | 2.91e-04 | 12 | 74 | 2 | 14964469 | |
| Pubmed | FGF signaling is required for anterior but not posterior specification of the murine liver bud. | 2.91e-04 | 12 | 74 | 2 | 25302779 | |
| Pubmed | 2.91e-04 | 12 | 74 | 2 | 12576423 | ||
| Pubmed | 2.91e-04 | 12 | 74 | 2 | 10751172 | ||
| Pubmed | 2.91e-04 | 12 | 74 | 2 | 12460940 | ||
| Pubmed | The roles of FGF signaling in germ cell migration in the mouse. | 2.91e-04 | 12 | 74 | 2 | 16291796 | |
| Pubmed | 2.91e-04 | 12 | 74 | 2 | 7959747 | ||
| Pubmed | 3.43e-04 | 13 | 74 | 2 | 9385055 | ||
| Pubmed | A point mutation in Fgf9 impedes joint interzone formation leading to multiple synostoses syndrome. | 3.43e-04 | 13 | 74 | 2 | 28169396 | |
| Pubmed | Testis Determination Requires a Specific FGFR2 Isoform to Repress FOXL2. | 3.43e-04 | 13 | 74 | 2 | 28938467 | |
| Pubmed | Constitutively active Galpha16 stimulates STAT3 via a c-Src/JAK- and ERK-dependent mechanism. | 3.43e-04 | 13 | 74 | 2 | 14551213 | |
| Pubmed | 3.43e-04 | 13 | 74 | 2 | 8883961 | ||
| Pubmed | Receptor specificity of the fibroblast growth factor family. | 3.43e-04 | 13 | 74 | 2 | 8663044 | |
| Pubmed | 3.84e-04 | 66 | 74 | 3 | 12666204 | ||
| Pubmed | 4.00e-04 | 14 | 74 | 2 | 11350938 | ||
| Pubmed | 4.00e-04 | 14 | 74 | 2 | 12432077 | ||
| Pubmed | FGF8 is essential for formation of the ductal system in the male reproductive tract. | 4.61e-04 | 15 | 74 | 2 | 22110055 | |
| Pubmed | 4.61e-04 | 15 | 74 | 2 | 28465335 | ||
| Pubmed | 4.76e-04 | 71 | 74 | 3 | 33541421 | ||
| Pubmed | A central chaperone-like role for 14-3-3 proteins in human cells. | 4.87e-04 | 861 | 74 | 8 | 36931259 | |
| Pubmed | 5.26e-04 | 16 | 74 | 2 | 15201220 | ||
| GeneFamily | Blood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing | 4.31e-04 | 161 | 40 | 4 | 593 | |
| ToppCell | 5'-Adult-LargeIntestine-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 7.89e-07 | 191 | 74 | 6 | 54f07e4de61735051498846afb44b1798bed8144 | |
| ToppCell | TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Non-keratinizing_Cervical_Squamous_Cell_Carcinoma-3|TCGA-Cervix / Sample_Type by Project: Shred V9 | 1.09e-05 | 175 | 74 | 5 | 0cc215109d9915af47e4d0a120ce2e46910715fa | |
| ToppCell | E16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 1.28e-05 | 181 | 74 | 5 | f6629fa71bb94405f523f63a9264cacf6d15c5f4 | |
| ToppCell | PND01-03-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A|PND01-03-samps / Age Group, Lineage, Cell class and subclass | 1.66e-05 | 191 | 74 | 5 | e7c605b56934d1383237c1f946dbccef25d91368 | |
| ToppCell | COVID_vent-Lymphocytic-ILC|COVID_vent / Disease condition, Lineage, Cell class and subclass | 2.02e-05 | 199 | 74 | 5 | e3ff7fa1b1de1aaf6b46cdf49afa95bad457728a | |
| ToppCell | COVID_vent-Lymphocytic-ILC-NK_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass | 2.02e-05 | 199 | 74 | 5 | 5f914962e2572b0c6372465b81b7496fa663d93c | |
| Drug | W-13, hydrochloride; Up 200; 10uM; MCF7; HG-U133A | 3.25e-06 | 194 | 74 | 7 | 440_UP | |
| Drug | Dihydroergotoxine mesylate [8067-24-1]; Up 200; 6.4uM; PC3; HT_HG-U133A | 3.72e-06 | 198 | 74 | 7 | 4071_UP | |
| Disease | bone disease (implicated_via_orthology) | 5.21e-05 | 5 | 68 | 2 | DOID:0080001 (implicated_via_orthology) | |
| Disease | free cholesterol in large HDL measurement | 8.17e-04 | 79 | 68 | 3 | EFO_0022157 | |
| Disease | Precursor B-cell lymphoblastic leukemia | 1.07e-03 | 21 | 68 | 2 | C1292769 | |
| Disease | Headache, type 2 diabetes mellitus | 1.28e-03 | 23 | 68 | 2 | HP_0002315, MONDO_0005148 | |
| Disease | oral squamous cell carcinoma (is_implicated_in) | 1.90e-03 | 28 | 68 | 2 | DOID:0050866 (is_implicated_in) |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| PFRDRVLHLLALRPY | 206 | P55199 | |
| YPLLLREILRHTPND | 266 | Q9NR81 | |
| TFRALSHPYSRPELL | 321 | Q03828 | |
| NYLLDVLERSPHRPI | 236 | P22455 | |
| NHLLPPEYTRTLRVL | 156 | Q3MIX3 | |
| RREHLSARQSPYFPL | 226 | Q5T5Y3 | |
| FPPLSSRLRYLIHRT | 41 | Q9Y3T6 | |
| RTPPHLLYSDRDRTF | 531 | Q8NDT2 | |
| PSREPRTHLAYALDL | 561 | Q9H1K0 | |
| YRSLSDPIPQRHRAA | 731 | Q96PE2 | |
| DSIRLPAHLRLQPIY | 46 | P41212 | |
| LLTRGQPPLYHLREV | 151 | Q5HYI7 | |
| RHPRLDEPLASYIFR | 1096 | Q96RG2 | |
| SNAVPLFLRLLRSPH | 156 | O00505 | |
| NIRHYLSEELRLPPQ | 486 | Q7L2J0 | |
| YEVQRRLRHLPSPIS | 76 | Q5YKI7 | |
| SPGDQRRLHRYLQRL | 991 | Q5JYT7 | |
| SVPYHQAALLRSPRR | 146 | Q96JJ6 | |
| QLRYSLRILIGDPPH | 86 | Q5H9J7 | |
| VPTARRPLSLLYLDH | 316 | P58166 | |
| SRLLPRVTSVHLPDY | 376 | O43312 | |
| PISYRLAEQQPLLRH | 636 | O14511 | |
| LRNDPLHRLSTPRLY | 1096 | Q8WXX7 | |
| LRRRLPPVLYDIHSR | 251 | Q96JK2 | |
| ILSYEHRPLKRPRLG | 6 | Q93074 | |
| QRLLLYHTHLRPRPR | 1721 | Q93074 | |
| LLNLRDPPREHPYRS | 356 | Q8WTR4 | |
| PHGITDVRPLYSRRL | 496 | P00451 | |
| LAIRYPLLVSHLRSP | 121 | Q9Y2T6 | |
| LRHSRQLEVPRPYIA | 1196 | Q13332 | |
| PLRRRPQLYYETSIH | 221 | Q8WY54 | |
| PYHRSRSTEQRPLLE | 1086 | Q9UQ26 | |
| LYRRHEPRFPELAAL | 391 | Q86VR8 | |
| YARLPLPLHRKARAL | 106 | Q8IYK2 | |
| LYRHRLNRQEIPPTL | 281 | Q8TCG5 | |
| AIRYPLHSRELRTPR | 126 | O43603 | |
| YERTLRRPVPLPHSL | 1906 | Q8N1I0 | |
| TLRRQHRPPALLTLY | 221 | Q96HP0 | |
| YQTLLLPRRHVRRLP | 251 | P07902 | |
| RTHRLPRAPRSSYLS | 781 | Q8N1P7 | |
| PHELRARLARAYRPA | 496 | Q674R7 | |
| ALPYLRLRHPLSVLG | 136 | Q8N6I1 | |
| EPLYSLRPEHARERL | 21 | P49356 | |
| LLQSREYSSLPLPRH | 76 | Q12912 | |
| ELTTLLRRYNIPHGP | 11 | P50402 | |
| YTLDVLERSPHRPIL | 241 | P22607 | |
| RPSYLDLFRTPRLRH | 331 | Q9Y694 | |
| PRYHSPLGLLRTRVT | 321 | A6NKX4 | |
| LEPYLRPRGQSATHR | 266 | Q8N4L8 | |
| IARRHPFLYAPTILL | 166 | P02771 | |
| PHRLGLPYKRSLRNL | 1166 | Q8N1G1 | |
| LYLRFLRSHPLPETA | 151 | Q9HCS7 | |
| NYTLLPPSLLDHRRG | 256 | O00204 | |
| PVLPVSYRLSHTRLA | 41 | Q6IEE7 | |
| RHYTLDASLPLRLRP | 176 | Q1AE95 | |
| LDALRTHYSPQRERP | 1066 | Q6ZNJ1 | |
| LNLSHNPRTLRYVPE | 26 | Q8NE22 | |
| HPPALRRQYLRLRGQ | 46 | Q9H1Z4 | |
| HPDPRQKALYRRLAT | 176 | O96005 | |
| LRQLVYRVHALPPSL | 2561 | Q63HN8 | |
| PRPQARASSRYLELH | 96 | Q6ZV60 | |
| RHYTLDASLPLRLRP | 176 | Q8IXX5 | |
| TSLRVPPDLLYQVRH | 2651 | O60673 | |
| PGRYRALPRRNHLYL | 26 | Q8WVR3 | |
| SDRYRHRLRVPLPTE | 281 | Q9H2B4 | |
| LYPRPRHNDRLRLLL | 576 | O94759 | |
| PRLSRRHLSLEPYLE | 51 | Q6ZNK6 | |
| TQLQLDERSHPPRYR | 51 | P53007 | |
| DPLLRQVPYRLHAVL | 576 | Q96RU2 | |
| LLDLNSHSLYRKPRP | 111 | Q6UXP9 | |
| PPLRQHYLQRLTSTV | 1371 | Q9BWH6 | |
| EHTPASLTRLPFLYR | 276 | A8MZF0 | |
| REPSPVRYDNLSRHI | 526 | Q9C0B5 | |
| LHAVPNLRDLPLRYL | 196 | Q8WUA8 | |
| PQEHRYTLRTSPRRA | 371 | Q8IYH5 | |
| PFPLRQIRNRRAYHL | 911 | Q9UPU7 | |
| VPLGSLRDYLPRHSI | 981 | P29597 |