Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionleukotriene-B4 20-monooxygenase activity

CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

9.82e-1071745GO:0050051
GeneOntologyMolecularFunctionalkane 1-monooxygenase activity

CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

9.82e-1071745GO:0018685
GeneOntologyMolecularFunctionarachidonate omega-hydroxylase activity

CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

1.15e-08101745GO:0052869
GeneOntologyMolecularFunctionfatty acid omega-hydroxylase activity

CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

1.15e-08101745GO:0120250
GeneOntologyMolecularFunctionlong-chain fatty acid omega-hydroxylase activity

CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

1.15e-08101745GO:0102033
GeneOntologyMolecularFunctionalpha-tocopherol omega-hydroxylase activity

CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.77e-0851744GO:0052871
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen

CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

5.77e-08131745GO:0016713
GeneOntologyMolecularFunctionarachidonate epoxygenase activity

CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

1.76e-06241745GO:0008392
GeneOntologyMolecularFunctionarachidonate monooxygenase activity

CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

3.28e-06271745GO:0008391
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

CYP7A1 CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

4.12e-06491746GO:0016712
GeneOntologyMolecularFunctionarachidonate binding

CYP4F2 CYP4A22 CYP4F12 CYP4F11

7.05e-06151744GO:0050544
GeneOntologyMolecularFunctionicosanoid binding

CYP4F2 CYP4A22 CYP4F12 CYP4F11

9.34e-06161744GO:0050542
GeneOntologyMolecularFunctionicosatetraenoic acid binding

CYP4F2 CYP4A22 CYP4F12 CYP4F11

9.34e-06161744GO:0050543
GeneOntologyMolecularFunctionaromatase activity

CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

1.25e-05351745GO:0070330
GeneOntologyMolecularFunctionprolactin receptor binding

GH1 CSH1 CSH2

2.22e-0571743GO:0005148
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

CYP7A1 CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.44e-05401745GO:0016709
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

FOXO3 NCOA3 TBX3 ZNF473 ZNF423 ZNF329 ZBTB22 SOX17 MLXIP ZNF236 ZNF865 CLOCK CREB5 ZFY STK16 ZNF711 HINFP ZNF668 WIZ ZNF425 ZNF408 ZNF197 ZFHX3 ATOH1 ZNF582 EP300 ZNF646 FOXP3

6.35e-05145917428GO:0000977
GeneOntologyMolecularFunctiongrowth hormone receptor binding

GH1 CSH1 CSH2

7.46e-05101743GO:0005131
GeneOntologyMolecularFunction20-hydroxy-leukotriene B4 omega oxidase activity

CYP4F2 CYP4F3

7.55e-0521742GO:0097258
GeneOntologyMolecularFunction20-aldehyde-leukotriene B4 20-monooxygenase activity

CYP4F2 CYP4F3

7.55e-0521742GO:0097259
GeneOntologyMolecularFunctionlong-chain fatty acid binding

CYP4F2 CYP4A22 CYP4F12 CYP4F11

9.68e-05281744GO:0036041
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

FOXO3 TBX3 ZNF473 ZNF423 ZBTB22 SOX17 MLXIP ZNF236 ZNF865 CLOCK CREB5 ZFY STK16 ZNF711 HINFP ZNF668 WIZ ZNF408 ZNF197 ZFHX3 ATOH1 EP300 ZNF646 FOXP3

2.08e-04124417424GO:0000978
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

FOXO3 NCOA3 TBX3 ZNF473 ZNF423 ZNF329 ZBTB22 SOX17 SAMD7 MLXIP ZNF236 CLOCK CREB5 ZFY ZNF711 HINFP ZNF668 WIZ ZNF425 ZNF408 ZNF197 ZFHX3 ATOH1 ZNF582 ZNF646 FOXP3

2.31e-04141217426GO:0000981
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

FOXO3 TBX3 ZNF473 ZNF423 ZBTB22 SOX17 MLXIP ZNF236 ZNF865 CLOCK CREB5 ZFY STK16 ZNF711 HINFP ZNF668 WIZ ZNF408 ZNF197 ZFHX3 ATOH1 EP300 ZNF646 FOXP3

2.85e-04127117424GO:0000987
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

CYP7A1 CYP4F2 CYP4A22 RSBN1 FADS3 CYP4F3 CYP4F12 CYP4F11

3.08e-041941748GO:0016705
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

FOXO3 NCOA3 TBX3 ZNF473 SOX17 MLXIP CLOCK CREB5 ZFY HINFP ZNF668 ZNF197 ATOH1 FOXP3

4.08e-0456017414GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

FOXO3 NCOA3 TBX3 ZNF473 SOX17 MLXIP CLOCK CREB5 ZFY HINFP ZNF668 ZNF197 ATOH1 FOXP3

4.53e-0456617414GO:0001216
GeneOntologyMolecularFunctionmonooxygenase activity

CYP7A1 CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

5.16e-041151746GO:0004497
GeneOntologyMolecularFunctioncalcium- and calmodulin-responsive adenylate cyclase activity

ADCY3 ADCY8

7.42e-0451742GO:0008294
GeneOntologyMolecularFunctiontranscription factor binding

FOXO3 NCOA3 STK36 TBX3 ZNF473 CENPF SOX17 CLOCK CIT NCAPG2 WIZ BBS7 NR0B1 NCOA7 EP300 FOXP3

9.30e-0475317416GO:0008134
GeneOntologyMolecularFunctionalpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity

ST6GALNAC1 ST6GALNAC4

1.11e-0361742GO:0001665
GeneOntologyMolecularFunctiondynein complex binding

CENPF CNTRL DNAAF8

1.82e-03281743GO:0070840
GeneOntologyMolecularFunctionchromatin binding

MKRN4P FOXO3 NCOA3 TICRR CENPF IFT74 POLE MKRN1 TSPYL6 SAMD7 CLOCK ZFY HINFP ATOH1 EP300

2.09e-0373917415GO:0003682
GeneOntologyMolecularFunctionheme binding

CYP7A1 CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

2.33e-031541746GO:0020037
GeneOntologyMolecularFunctionprotein kinase activity

STK36 HIPK4 CDK15 ROR1 ROR2 STYK1 TEX14 CIT STK16 MAP3K11 PRKCZ MAP3K13 TSSK1B

2.36e-0360017413GO:0004672
GeneOntologyMolecularFunctionkinase activity

STK36 HIPK4 CDK15 ROR1 ROR2 STYK1 TEX14 CIT AK8 STK16 MAP3K11 PIP5K1A PRKCZ MAP3K13 TSSK1B

2.87e-0376417415GO:0016301
GeneOntologyMolecularFunctionfatty acid binding

CYP4F2 CYP4A22 CYP4F12 CYP4F11

3.10e-03691744GO:0005504
GeneOntologyMolecularFunctiontetrapyrrole binding

CYP7A1 CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

3.19e-031641746GO:0046906
GeneOntologyMolecularFunctionhormone receptor binding

GH1 CSH1 CSH2

3.19e-03341743GO:0051427
GeneOntologyMolecularFunctioniron ion binding

CYP7A1 CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

3.38e-031661746GO:0005506
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

STK36 HIPK4 CDK15 POLE ROR1 ROR2 STYK1 POLRMT TEX14 CIT AK8 STK16 MAP3K11 PIP5K1A PRKCZ MAP3K13 TSSK1B

3.49e-0393817417GO:0016772
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

STK36 HIPK4 CDK15 ROR1 ROR2 STYK1 TEX14 CIT STK16 MAP3K11 PIP5K1A PRKCZ MAP3K13 TSSK1B

3.75e-0370917414GO:0016773
GeneOntologyBiologicalProcessleukotriene B4 catabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

7.08e-0861734GO:0036101
GeneOntologyBiologicalProcessleukotriene B4 metabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.64e-0771734GO:0036102
GeneOntologyBiologicalProcessleukotriene catabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.26e-0781734GO:0036100
GeneOntologyBiologicalProcessmenaquinone catabolic process

CYP4F2 CYP4F12 CYP4F11

5.80e-0731733GO:0042361
GeneOntologyBiologicalProcessicosanoid catabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.51e-06111734GO:1901523
GeneOntologyBiologicalProcesslong-chain fatty acid catabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.25e-06121734GO:0042758
GeneOntologyBiologicalProcessphylloquinone metabolic process

CYP4F2 CYP4F12 CYP4F11

2.31e-0641733GO:0042374
GeneOntologyBiologicalProcessphylloquinone catabolic process

CYP4F2 CYP4F12 CYP4F11

2.31e-0641733GO:0042376
GeneOntologyBiologicalProcessvitamin K catabolic process

CYP4F2 CYP4F12 CYP4F11

2.31e-0641733GO:0042377
GeneOntologyBiologicalProcessmenaquinone metabolic process

CYP4F2 CYP4F12 CYP4F11

2.31e-0641733GO:0009233
GeneOntologyBiologicalProcessomega-hydroxylase P450 pathway

CYP4F2 CYP4A22 CYP4F12 CYP4F11

4.48e-06141734GO:0097267
GeneOntologyBiologicalProcessregulation of intracellular steroid hormone receptor signaling pathway

NCOA3 CLOCK GH1 CSH1 CSH2 NR0B1 EP300

8.59e-06871737GO:0033143
GeneOntologyBiologicalProcessprostaglandin catabolic process

CYP4F2 CYP4F12 CYP4F11

1.14e-0561733GO:1905344
GeneOntologyBiologicalProcessprostanoid catabolic process

CYP4F2 CYP4F12 CYP4F11

1.14e-0561733GO:0062232
GeneOntologyBiologicalProcessgamete generation

FOXO3 DNHD1 RHBDD1 DMXL2 ARMC3 CNTRL SOX17 FANCL APOB PIWIL2 TEX14 MEI1 SSX1 CLOCK CIT ZFY NR0B1 SEPTIN1 ZPBP2 DLEC1 TSSK1B BAG6

2.61e-0598217322GO:0007276
GeneOntologyBiologicalProcessfatty acid derivative catabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.11e-05221734GO:1901569
GeneOntologyBiologicalProcesssexual reproduction

FOXO3 DNHD1 RHBDD1 DMXL2 ARMC3 CNTRL SOX17 FANCL APOB PIWIL2 TEX14 MEI1 SSX1 CLOCK CIT ADCY3 ZFY UMODL1 NR0B1 SEPTIN1 ZPBP2 DLEC1 TSSK1B BAG6 CPEB1 NLRP5

3.77e-05131217326GO:0019953
GeneOntologyBiologicalProcessnuclear chromosome segregation

CENPF CEP192 TEX14 MEI1 CIT NCAPG2 KIF15 TRAPPC12 SEPTIN1 FAM83D BAG6 CPEB1

4.91e-0535617312GO:0098813
GeneOntologyBiologicalProcessprophase

PIWIL2 MEI1 XRCC5

6.66e-05101733GO:0051324
GeneOntologyBiologicalProcessmeiotic prophase I

PIWIL2 MEI1 XRCC5

6.66e-05101733GO:0007128
GeneOntologyBiologicalProcessmale gamete generation

DNHD1 RHBDD1 DMXL2 ARMC3 SOX17 APOB PIWIL2 TEX14 MEI1 SSX1 CLOCK CIT ZFY NR0B1 ZPBP2 DLEC1 TSSK1B BAG6

7.63e-0576217318GO:0048232
GeneOntologyBiologicalProcessvitamin K metabolic process

CYP4F2 CYP4F12 CYP4F11

9.11e-05111733GO:0042373
GeneOntologyBiologicalProcessregulation of neurogenesis

MAN2A1 WNT2 TSC2 XRCC5 CIT GH1 SLIT2 CSH1 CSH2 SLIT1 LRP4 MAP3K13 ATOH1 EP300

1.18e-0451517314GO:0050767
GeneOntologyBiologicalProcessmeiosis I cell cycle phase

PIWIL2 MEI1 XRCC5

1.21e-04121733GO:0098764
GeneOntologyBiologicalProcessfat-soluble vitamin catabolic process

CYP4F2 CYP4F12 CYP4F11

1.21e-04121733GO:0042363
GeneOntologyBiologicalProcessnuclear receptor-mediated steroid hormone signaling pathway

NCOA3 CLOCK GH1 CSH1 CSH2 NR0B1 EP300

1.52e-041361737GO:0030518
GeneOntologyBiologicalProcesspositive regulation of steroid hormone biosynthetic process

GH1 CSH1 CSH2

1.56e-04131733GO:0090031
GeneOntologyBiologicalProcessembryo development

NCOA3 TBX3 MAN2A1 MYO7A WNT2 POLE DZIP1L ROR2 SOX17 AMBRA1 TSC2 APOB NCAPG2 ZFY HINFP SLIT2 PLPP3 BBS7 NR0B1 MIB1 LRP4 ATOH1 ATP2B2 BAG6 EP300 NLRP5

1.67e-04143717326GO:0009790
GeneOntologyBiologicalProcessmulticellular organismal reproductive process

FOXO3 DNHD1 RHBDD1 DMXL2 ARMC3 CNTRL SOX17 FANCL APOB PIWIL2 TEX14 MEI1 SSX1 CLOCK CIT ZFY UMODL1 NR0B1 SEPTIN1 ZPBP2 DLEC1 TSSK1B BAG6

1.68e-04119417323GO:0048609
GeneOntologyBiologicalProcesscell cycle process

TICRR NUGGC CENPF POLE AMBRA1 PIWIL2 CEP192 TEX14 MEI1 CLOCK CIT NCAPG2 TTC19 ZFY HINFP WIZ KIF15 TRAPPC12 SEPTIN1 MAP3K11 FAM83D CSPP1 MN1 BAG6 CPEB1 NLRP5

1.74e-04144117326GO:0022402
GeneOntologyBiologicalProcessspermatogenesis

DNHD1 RHBDD1 DMXL2 ARMC3 SOX17 APOB PIWIL2 MEI1 SSX1 CLOCK CIT ZFY NR0B1 ZPBP2 DLEC1 TSSK1B BAG6

1.81e-0474417317GO:0007283
GeneOntologyBiologicalProcessmeiotic cell cycle phase

PIWIL2 MEI1 XRCC5

1.97e-04141733GO:0098762
GeneOntologyBiologicalProcessM phase

PIWIL2 MEI1 XRCC5

1.97e-04141733GO:0000279
GeneOntologyBiologicalProcesschemorepulsion involved in embryonic olfactory bulb interneuron precursor migration

SLIT2 SLIT1

2.09e-0431732GO:0021834
GeneOntologyBiologicalProcesspositive regulation of muscle atrophy

FOXO3 EP300

2.09e-0431732GO:0014737
GeneOntologyBiologicalProcessarachidonate metabolic process

CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

2.66e-04681735GO:0019369
GeneOntologyBiologicalProcesshead development

FOXO3 STK36 TBX3 DMXL2 CENPF WNT2 ZNF423 PFAS AK8 CHRNB2 SLIT2 BBS7 SLIT1 NR0B1 ATOH1 GMPPA ATP2B2 BAG6 EP300

2.69e-0491917319GO:0060322
GeneOntologyBiologicalProcessregulation of steroid biosynthetic process

CYP7A1 APOB GH1 CSH1 CSH2 NR0B1

2.72e-041061736GO:0050810
GeneOntologyBiologicalProcessdevelopmental process involved in reproduction

FOXO3 DNHD1 NCOA3 RHBDD1 TBX3 DMXL2 ARMC3 CNTRL ROR2 SOX17 APOB PIWIL2 MEI1 SSX1 CLOCK CIT ZFY UMODL1 NR0B1 ZPBP2 DLEC1 TSSK1B BAG6

2.73e-04123517323GO:0003006
GeneOntologyBiologicalProcesssensory perception of sound

USP53 MYO7A ROR1 ADGRV1 CHRNB2 FAM107B ELMOD3 ATP2B2

2.74e-041981738GO:0007605
GeneOntologyBiologicalProcesspositive regulation of steroid biosynthetic process

CYP7A1 GH1 CSH1 CSH2

2.82e-04381734GO:0010893
GeneOntologyBiologicalProcessnuclear receptor-mediated signaling pathway

NCOA3 CLOCK GH1 CSH1 CSH2 NR0B1 MN1 EP300

3.14e-042021738GO:0141193
GeneOntologyBiologicalProcesssteroid hormone receptor signaling pathway

NCOA3 CLOCK GH1 CSH1 CSH2 NR0B1 EP300

3.40e-041551737GO:0043401
GeneOntologyBiologicalProcessorganic hydroxy compound catabolic process

CYP7A1 CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.71e-04731735GO:1901616
GeneOntologyBiologicalProcessleukotriene metabolic process

CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.80e-04411734GO:0006691
GeneOntologyBiologicalProcessdorsal/ventral axon guidance

SLIT2 SLIT1

4.15e-0441732GO:0033563
GeneOntologyBiologicalProcesspositive regulation of steroid metabolic process

CYP7A1 GH1 CSH1 CSH2

4.17e-04421734GO:0045940
GeneOntologyBiologicalProcessvitamin catabolic process

CYP4F2 CYP4F12 CYP4F11

4.31e-04181733GO:0009111
GeneOntologyBiologicalProcesscentral nervous system development

FOXO3 STK36 TBX3 DMXL2 MYCBP2 CENPF WNT2 ZNF423 ROR1 ROR2 AK8 CHRNB2 SLIT2 PLPP3 BBS7 SLIT1 NR0B1 ATOH1 GMPPA ATP2B2 BAG6 FOXP3

4.47e-04119717322GO:0007417
GeneOntologyBiologicalProcesspositive regulation of hormone biosynthetic process

GH1 CSH1 CSH2

5.09e-04191733GO:0046886
GeneOntologyBiologicalProcesschromosome segregation

CENPF CEP192 TEX14 MEI1 CIT NCAPG2 KIF15 TRAPPC12 SEPTIN1 FAM83D BAG6 CPEB1

5.77e-0446517312GO:0007059
GeneOntologyBiologicalProcessestablishment of chromosome localization

CENPF TEX14 MEI1 TRAPPC12 SEPTIN1 FAM83D

5.78e-041221736GO:0051303
GeneOntologyBiologicalProcessregulation of response to nutrient levels

GH1 CSH1 CSH2 MN1

5.93e-04461734GO:0032107
GeneOntologyBiologicalProcessfatty acid derivative metabolic process

TECR CYP4F2 CYP4F3 CYP4F12 CYP4F11

6.35e-04821735GO:1901568
GeneOntologyBiologicalProcessembryonic olfactory bulb interneuron precursor migration

SLIT2 SLIT1

6.88e-0451732GO:0021831
GeneOntologyBiologicalProcessregulation of muscle atrophy

FOXO3 EP300

6.88e-0451732GO:0014735
GeneOntologyBiologicalProcessketone catabolic process

CYP4F2 CYP4F12 CYP4F11

6.90e-04211733GO:0042182
GeneOntologyBiologicalProcesspositive regulation of cell development

FOXO3 MAN2A1 WNT2 ROR2 AMBRA1 XRCC5 GH1 SLIT2 CSH1 CSH2 PRKCZ MAP3K13 EP300 FOXP3

6.94e-0461417314GO:0010720
GeneOntologyBiologicalProcessunsaturated fatty acid metabolic process

CYP4F2 CYP4A22 FADS3 CYP4F3 CYP4F12 CYP4F11

7.44e-041281736GO:0033559
GeneOntologyBiologicalProcesschromosome localization

CENPF TEX14 MEI1 TRAPPC12 SEPTIN1 FAM83D

8.07e-041301736GO:0050000
GeneOntologyBiologicalProcessregulation of nervous system development

MAN2A1 WNT2 TSC2 XRCC5 CIT GH1 SLIT2 CSH1 CSH2 SLIT1 LRP4 MAP3K13 ATOH1 EP300

8.24e-0462517314GO:0051960
GeneOntologyBiologicalProcessregulation of cell development

FOXO3 MAN2A1 WNT2 ROR2 AMBRA1 TSC2 XRCC5 CLOCK CIT GH1 SLIT2 CSH1 CSH2 SLIT1 LRP4 PRKCZ MAP3K13 ATOH1 EP300 FOXP3

8.89e-04109517320GO:0060284
GeneOntologyBiologicalProcesssensory perception of mechanical stimulus

USP53 MYO7A ROR1 ADGRV1 CHRNB2 FAM107B ELMOD3 ATP2B2

9.23e-042381738GO:0050954
GeneOntologyBiologicalProcessbrain development

FOXO3 STK36 TBX3 DMXL2 CENPF WNT2 ZNF423 AK8 CHRNB2 SLIT2 BBS7 SLIT1 NR0B1 ATOH1 GMPPA ATP2B2 BAG6

9.26e-0485917317GO:0007420
GeneOntologyBiologicalProcesscellular response to steroid hormone stimulus

FOXO3 NCOA3 CLOCK GH1 CSH1 CSH2 NR0B1 EP300

9.48e-042391738GO:0071383
GeneOntologyBiologicalProcessregulation of steroid metabolic process

CYP7A1 APOB GH1 CSH1 CSH2 NR0B1

9.83e-041351736GO:0019218
GeneOntologyBiologicalProcessinner ear receptor cell stereocilium organization

MYO7A ADGRV1 ELMOD3 ATP2B2

1.02e-03531734GO:0060122
GeneOntologyBiologicalProcessvitamin E metabolic process

CYP4F2 CYP4F12

1.03e-0361732GO:0042360
GeneOntologyBiologicalProcessleptotene

MEI1 XRCC5

1.03e-0361732GO:0000237
GeneOntologyBiologicalProcessregulation of steroid hormone biosynthetic process

GH1 CSH1 CSH2

1.03e-03241733GO:0090030
GeneOntologyBiologicalProcesshormone-mediated signaling pathway

NCOA3 CLOCK GH1 CSH1 CSH2 NR0B1 MN1 EP300

1.08e-032441738GO:0009755
GeneOntologyCellularComponentgrowth hormone receptor complex

GH1 CSH1 CSH2

1.06e-0561713GO:0070195
GeneOntologyCellularComponentcilium

DNHD1 TBX3 FBXL13 CENPF MYO7A IFT74 DZIP1L CNTRL EVC AMBRA1 ADGRV1 SSX1 ADCY3 AK8 BBS7 ELMOD3 DLEC1 TSSK1B ATP2B2

1.45e-0489817119GO:0005929
GeneOntologyCellularComponentmeiotic spindle

CNTRL SEPTIN1 CPEB1

4.73e-04191713GO:0072687
GeneOntologyCellularComponentmidbody

TTC28 CENPF CNTRL TEX14 CIT TTC19 WIZ SEPTIN1

4.98e-042221718GO:0030496
GeneOntologyCellularComponentmicrotubule organizing center

FBXL13 TTC28 CENPF IFT74 DZIP1L CNTRL EVC CEP192 TTC19 KIF15 BBS7 NR0B1 MIB1 SEPTIN1 MAP3K11 PRKCZ CSPP1 CPEB1

5.50e-0491917118GO:0005815
MousePhenoadvanced circadian behavior phase

CLOCK SYT10 ZFHX3

8.12e-0651323MP:0020474
MousePhenopersistence of hyaloid vascular system

NCOA3 MYO7A CYP7A1 ZNF423 ROR2 CYP4F2 CHRNB2 CYP4F12 FGD5 PRKCZ CYP4F11

8.49e-0622313211MP:0001289
MousePhenoabnormal distortion product otoacoustic emission

USP53 MYO7A ROR1 ADGRV1 ELMOD3 ATOH1 ATP2B2

1.53e-05851327MP:0004736
MousePhenoabnormal otoacoustic response

USP53 MYO7A ROR1 ADGRV1 ELMOD3 ATOH1 ATP2B2

1.65e-05861327MP:0006336
MousePhenoabnormal male reproductive system physiology

DNHD1 TPTE STK36 TBX3 HIPK4 ARMC3 LKAAEAR1 MYO7A ROR2 FANCL APOB PIWIL2 TEX14 MEI1 XRCC5 CIT ADCY3 GH1 CSH1 CSH2 BBS7 NR0B1 PIP5K1A ZPBP2 DLEC1 CCDC183 CPEB1 FOXP3

3.82e-05132913228MP:0003698
MousePhenoabnormal outer hair cell stereociliary bundle morphology

USP53 MYO7A ADGRV1 ELMOD3 ATOH1 ATP2B2

4.29e-05681326MP:0004527
MousePhenodecreased pituitary gland weight

GH1 CSH1 CSH2

4.45e-0581323MP:0008938
MousePhenoabnormal vitreous body morphology

NCOA3 MAN2A1 MYO7A CYP7A1 ZNF423 ROR2 CYP4F2 CHRNB2 SLIT2 NUP210 CYP4F12 FGD5 PRKCZ CYP4F11

5.37e-0542913214MP:0002699
MousePhenoabsent somatotrophs

GH1 CSH1 CSH2

6.63e-0591323MP:0008330
MousePhenoabsent lactotrophs

GH1 CSH1 CSH2

6.63e-0591323MP:0008333
MousePhenoabsent cochlear hair bundle ankle links

MYO7A ADGRV1

8.85e-0521322MP:0004582
MousePhenoabnormal cochlear hair bundle ankle links morphology

MYO7A ADGRV1

8.85e-0521322MP:0004581
MousePhenoabnormal spermatogenesis

DNHD1 TPTE HIPK4 ARMC3 ROR2 FANCL APOB PIWIL2 TEX14 MEI1 CIT ADCY3 ZFY BBS7 NR0B1 PIP5K1A ZPBP2 DLEC1 CCDC183 CPEB1 FOXP3

1.20e-0491013221MP:0001156
MousePhenodelayed vaginal opening

NCOA3 GH1 CSH1 CSH2

1.30e-04281324MP:0002636
MousePhenoabnormal male germ cell morphology

DNHD1 TPTE HIPK4 ARMC3 ROR2 FANCL APOB PIWIL2 TEX14 MEI1 CIT ZFY BBS7 NR0B1 PIP5K1A ZPBP2 DLEC1 CCDC183 CPEB1 FOXP3

1.57e-0485913220MP:0006362
MousePhenoincreased circulating ghrelin level

GH1 CSH1 CSH2

1.70e-04121323MP:0011612
MousePhenoabnormal pituitary gland weight

GH1 CSH1 CSH2

1.70e-04121323MP:0008937
MousePhenosmall liver

NCOA3 TBX3 ZBTB22 SOX17 TSC2 ZNF236 GH1 CSH1 CSH2 NUP210 FGD5

1.96e-0431513211MP:0000601
MousePhenoabnormal timing of vaginal opening

NCOA3 GH1 CSH1 CSH2

1.96e-04311324MP:0020150
MousePhenocochlear inner hair cell degeneration

USP53 ADGRV1 ELMOD3 ATOH1 ATP2B2

1.97e-04571325MP:0004398
MousePhenoabnormal germ cell morphology

FOXO3 DNHD1 TPTE HIPK4 ARMC3 ROR2 FANCL APOB PIWIL2 TEX14 MEI1 CIT ZFY BBS7 NR0B1 PIP5K1A ZPBP2 DLEC1 CCDC183 CPEB1 FOXP3

2.05e-0494613221MP:0002208
MousePhenoabnormal cochlear hair cell stereociliary bundle morphology

USP53 MYO7A ADGRV1 ELMOD3 ATOH1 ATP2B2

2.19e-04911326MP:0004521
MousePhenoabnormal foam cell morphology

FOXO3 DNHD1 TPTE HIPK4 ARMC3 ROR2 FANCL APOB PIWIL2 TEX14 MEI1 CIT ZFY BBS7 NR0B1 PIP5K1A ZPBP2 DLEC1 CCDC183 CPEB1 FOXP3

2.30e-0495413221MP:0009840
MousePhenoinfertility

FOXO3 DNHD1 STK36 HIPK4 ARMC3 LKAAEAR1 MYO7A EVC FANCL PIWIL2 TEX14 MEI1 XRCC5 GH1 CSH1 CSH2 BBS7 NR0B1 DLEC1 CCDC183 ATP2B2 CPEB1 NLRP5 FOXP3

2.85e-04118813224MP:0001924
MousePhenoabnormal circulating ghrelin level

GH1 CSH1 CSH2

3.45e-04151323MP:0011611
MousePhenoabnormal gametogenesis

FOXO3 DNHD1 TPTE HIPK4 ARMC3 ROR2 FANCL APOB PIWIL2 TEX14 MEI1 CIT ADCY3 ZFY BBS7 NR0B1 PIP5K1A ZPBP2 DLEC1 CCDC183 CPEB1 FOXP3

4.16e-04107013222MP:0001929
MousePhenoabnormal susceptibility to hearing loss

USP53 MYO7A ADGRV1 ATP2B2

4.37e-04381324MP:0006334
MousePhenocochlear hair cell degeneration

USP53 MYO7A ADGRV1 ELMOD3 ATOH1 ATP2B2

4.99e-041061326MP:0004362
MousePhenodecreased lactotroph cell number

GH1 CSH1 CSH2

5.08e-04171323MP:0008332
MousePhenoabnormal diencephalon morphology

FOXO3 DMXL2 MYCBP2 ZNF423 CIT CHRNB2 GH1 CSH1 CSH2 BBS7

5.26e-0429813210MP:0000830
DomainZINC_FINGER_C2H2_2

ZXDC ZNF473 ZNF423 DZIP1L ZNF329 ZBTB22 CPXCR1 ZNF236 ZNF865 CREB5 ZFY ZNF711 HINFP ZNF668 WIZ ZNF425 ZNF408 ZNF197 ZFHX3 ZNF582 ZNF646 FOXP3

3.00e-0677517322PS50157
DomainZnf_C2H2-like

ZXDC ZNF473 ZNF423 DZIP1L ZNF329 ZBTB22 CPXCR1 ZNF236 ZNF865 CREB5 ZFY ZNF711 HINFP ZNF668 WIZ ZNF425 ZNF408 ZNF197 ZFHX3 ZNF582 ZNF646 FOXP3

4.61e-0679617322IPR015880
DomainZnf_C2H2

ZXDC ZNF473 ZNF423 DZIP1L ZNF329 ZBTB22 CPXCR1 ZNF236 ZNF865 CREB5 ZFY ZNF711 HINFP ZNF668 WIZ ZNF425 ZNF408 ZNF197 ZFHX3 ZNF582 ZNF646 FOXP3

5.51e-0680517322IPR007087
DomainZnF_C2H2

ZXDC ZNF473 ZNF423 DZIP1L ZNF329 ZBTB22 CPXCR1 ZNF236 ZNF865 CREB5 ZFY ZNF711 HINFP ZNF668 WIZ ZNF425 ZNF408 ZNF197 ZFHX3 ZNF582 ZNF646 FOXP3

5.84e-0680817322SM00355
DomainCyt_P450_CS

CYP7A1 CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

9.27e-06531736IPR017972
DomainZINC_FINGER_C2H2_1

ZXDC ZNF473 ZNF423 DZIP1L ZNF329 ZBTB22 ZNF236 ZNF865 CREB5 ZFY ZNF711 HINFP ZNF668 WIZ ZNF425 ZNF408 ZNF197 ZFHX3 ZNF582 ZNF646 FOXP3

1.08e-0577717321PS00028
DomainCYTOCHROME_P450

CYP7A1 CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

1.42e-05571736PS00086
DomainSOMATOTROPIN_2

GH1 CSH1 CSH2

1.53e-0561733PS00338
DomainSOMATOTROPIN_1

GH1 CSH1 CSH2

1.53e-0561733PS00266
DomainHormone_1

GH1 CSH1 CSH2

1.53e-0561733PF00103
Domain-

CYP7A1 CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

1.57e-055817361.10.630.10
Domainp450

CYP7A1 CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

1.57e-05581736PF00067
Domain-

ZXDC ZNF473 ZNF423 ZNF329 ZBTB22 ZNF236 ZNF865 CREB5 ZFY ZNF711 HINFP ZNF668 ZNF425 ZNF408 ZNF197 ZFHX3 ZNF582 ZNF646 FOXP3

1.82e-05679173193.30.160.60
DomainCyt_P450

CYP7A1 CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

1.92e-05601736IPR001128
DomainZnf_C2H2/integrase_DNA-bd

ZXDC ZNF473 ZNF423 ZNF329 ZBTB22 ZNF236 ZNF865 CREB5 ZFY ZNF711 HINFP ZNF668 ZNF425 ZNF408 ZNF197 ZFHX3 ZNF582 ZNF646 FOXP3

2.46e-0569417319IPR013087
DomainSomatotropin

GH1 CSH1 CSH2

2.66e-0571733IPR001400
DomainCyt_P450_E_grp-I

CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

5.82e-05451735IPR002401
DomainTyr_kinase_rcpt_ROR

ROR1 ROR2

8.53e-0521732IPR016247
Domainzf-C2H2_6

ZNF473 ZNF423 ZNF329 ZNF236 ZNF865 ZNF668 ZNF425 ZNF408 ZNF197 ZNF582 ZNF646

1.71e-0431417311PF13912
DomainTranscrp_activ_Zfx/Zfy-dom

ZFY ZNF711

2.54e-0431732IPR006794
DomainZfx_Zfy_act

ZFY ZNF711

2.54e-0431732PF04704
Domain4_helix_cytokine-like_core

ZNF236 ZFY GH1 CSH1 CSH2

6.19e-04741735IPR009079
DomainProt_kinase_dom

STK36 HIPK4 CDK15 ROR1 ROR2 STYK1 TEX14 CIT STK16 MAP3K11 PRKCZ MAP3K13 TSSK1B

6.51e-0448917313IPR000719
DomainPROTEIN_KINASE_DOM

STK36 HIPK4 CDK15 ROR1 ROR2 STYK1 TEX14 CIT STK16 MAP3K11 PRKCZ MAP3K13 TSSK1B

7.01e-0449317313PS50011
Domainzf-C2H2

ZNF473 ZNF423 ZNF329 ZBTB22 ZNF236 ZNF865 ZFY ZNF711 HINFP ZNF668 ZNF425 ZNF408 ZNF197 ZFHX3 ZNF582 ZNF646

7.34e-0469317316PF00096
DomainSomatotropin_CS

GH1 CSH1

8.38e-0451732IPR018116
Domain-

LCMT2 KLHL11 KLHL30 KLHL14

1.01e-034817342.120.10.80
DomainPROTEIN_KINASE_ATP

STK36 HIPK4 CDK15 ROR1 ROR2 STYK1 CIT STK16 MAP3K11 PRKCZ MAP3K13 TSSK1B

1.21e-0345917312PS00107
DomainNuc_rcpt_coact

NCOA3 EP300

1.25e-0361732IPR009110
DomainPkinase_Tyr

ROR1 ROR2 STYK1 TEX14 MAP3K11 MAP3K13

1.29e-031291736PF07714
PathwayREACTOME_EICOSANOIDS

CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

3.10e-08121205M27129
PathwayREACTOME_EICOSANOIDS

CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

3.10e-08121205MM14845
PathwayWP_EICOSANOID_METABOLISM_VIA_CYTOCHROME_P450_MONOOXYGENASES

CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

7.74e-08141205MM15842
PathwayREACTOME_FATTY_ACIDS

CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

1.15e-07151205M27126
PathwayREACTOME_MISCELLANEOUS_SUBSTRATES

CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

3.22e-07181205MM14843
PathwayREACTOME_FATTY_ACIDS

CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

3.22e-07181205MM14841
PathwayREACTOME_SYNTHESIS_OF_16_20_HYDROXYEICOSATETRAENOIC_ACIDS_HETE

CYP4F2 CYP4A22 CYP4F12 CYP4F11

1.57e-06111204MM14863
PathwayREACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

1.91e-06251205MM14858
PathwayREACTOME_MISCELLANEOUS_SUBSTRATES

CYP4F2 CYP4A22 CYP4F3 CYP4F11

2.35e-06121204M27128
PathwayWP_EICOSANOID_METABOLISM_VIA_CYCLOOXYGENASES_COX

CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

8.06e-06331205MM15918
PathwayWP_EICOSANOID_METABOLISM_VIA_LIPOXYGENASES_LOX

CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

8.06e-06331205MM15963
PathwayWP_OXIDATION_BY_CYTOCHROME_P450

CYP7A1 CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

1.40e-05621206M39653
PathwayREACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE

CYP7A1 CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

1.68e-05641206M5650
PathwayBIOCARTA_LONGEVITY_PATHWAY

FOXO3 GH1 CSH1 CSH2

1.75e-05191204MM1513
PathwayREACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE

CYP7A1 CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

2.01e-05661206MM14839
PathwayREACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

CYP4F2 CYP4A22 CYP4F3 CYP4F11

2.67e-05211204M27137
PathwayWP_EICOSANOID_METABOLISM_VIA_CYTOCHROME_P450_MONOOXYGENASES_PATHWAY

CYP4F2 CYP4A22 CYP4F12

4.87e-0591203M39819
PathwayBIOCARTA_AKT_PATHWAY

FOXO3 GH1 CSH1 CSH2

6.46e-05261204MM1345
PathwayKEGG_MEDICUS_REFERENCE_GHRHR_PKA_GH_SIGNALING_PATHWAY

ADCY3 CREB5 ADCY8 GH1

8.73e-05281204M47647
PathwayREACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL

MKRN4P MKRN1 TSC2

1.25e-04121203MM14777
PathwayREACTOME_PROLACTIN_RECEPTOR_SIGNALING

GH1 CSH1 CSH2

1.62e-04131203MM14516
PathwayREACTOME_ARACHIDONIC_ACID_METABOLISM

CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

1.67e-04611205MM14861
PathwayREACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS

CYP7A1 CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

2.58e-041041206M738
PathwayREACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS

CYP7A1 CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

2.72e-041051206MM14842
PathwayREACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING

GH1 CSH1 CSH2

3.11e-04161203MM15710
PathwayREACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN

GH1 CSH1 CSH2

6.17e-04201203MM15070
PathwayBIOCARTA_VDR_PATHWAY

NCOA3 TSC2 EP300

8.23e-04221203MM1370
Pubmed

Regulation of somatic growth by the p160 coactivator p/CIP.

NCOA3 GH1 CSH1 CSH2 EP300

4.11e-109178511087842
Pubmed

Omega oxidation of 3-hydroxy fatty acids by the human CYP4F gene subfamily enzyme CYP4F11.

CYP4F2 CYP4F3 CYP4F12 CYP4F11

6.63e-104178418065749
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FOXO3 ZXDC PHLDB3 STK36 MYCBP2 MYO7A POLE POLRMT AMBRA1 PFAS TSC2 CEP192 MLXIP ZNF236 ZNF865 CIT WIZ TRAPPC12 ZNF408 LRP4 MAP3K11 DTX2 EP300 RIC1

2.71e-0911051782435748872
Pubmed

The cytochrome P450 4 (CYP4) family.

CYP4F2 CYP4F3 CYP4F12 CYP4F11

9.87e-09617849068972
Pubmed

Ovarian aging and the activation of the primordial follicle reserve in the long-lived Ames dwarf and the short-lived bGH transgenic mice.

FOXO3 GH1 CSH1 CSH2

2.29e-087178427771355
Pubmed

A molecular circuit composed of CPEB-1 and c-Jun controls growth hormone-mediated synaptic plasticity in the mouse hippocampus.

GH1 CSH1 CSH2 CPEB1

2.29e-087178418716208
Pubmed

The MN1 oncoprotein synergizes with coactivators RAC3 and p300 in RAR-RXR-mediated transcription.

NCOA3 MN1 EP300

1.32e-073178312569362
Pubmed

Splicing variants of the human growth hormone mRNA: detection in pituitary, mononuclear cells and dermal fibroblasts.

GH1 CSH1 CSH2

1.32e-07317838674830
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

MKRN4P FOXO3 ZXDC NCOA3 TBX3 ZNF473 ZNF423 MKRN1 ZBTB22 SOX17 ZNF236 CLOCK HINFP ZNF668 WIZ NR0B1 ZFHX3 ZNF646

2.07e-078081781820412781
Pubmed

Atbf1 is required for the Pit1 gene early activation.

GH1 CSH1 CSH2 ZFHX3

4.57e-0713178418272476
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

USP53 FOXO3 HIPK4 TTC28 MYCBP2 IFT74 ROR2 TSC2 CEP192 MLXIP TAB3 ARHGEF1 RABGAP1L NCOA7 USP54 TSSK1B CSPP1 SEC23B

5.21e-078611781836931259
Pubmed

Disruption of mouse cytochrome p450 4f14 (Cyp4f14 gene) causes severe perturbations in vitamin E metabolism.

CYP4F2 CYP4F12 CYP4F11

5.25e-074178322665481
Pubmed

Expression and catalytic activity of mouse leukotriene B4 omega-hydroxylase, CYP4F14.

CYP4F2 CYP4F12 CYP4F11

5.25e-074178311185557
Pubmed

The human growth hormone gene family: nucleotide sequences show recent divergence and predict a new polypeptide hormone.

GH1 CSH1 CSH2

5.25e-07417837169009
Pubmed

Involvement of the TRAP220 component of the TRAP/SMCC coactivator complex in embryonic development and thyroid hormone action.

NCOA3 GH1 CSH1 CSH2

1.15e-0616178410882104
Pubmed

Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning.

MYO7A ADGRV1 ADCY3 ADCY8

1.15e-0616178417567809
Pubmed

Central growth hormone action regulates metabolism during pregnancy.

GH1 CSH1 CSH2

1.31e-065178331479305
Pubmed

Molecular evolution of growth hormone and receptor in the guinea-pig, a mammal unresponsive to growth hormone.

GH1 CSH1 CSH2

1.31e-065178310767558
Pubmed

Disruption of P450-mediated vitamin E hydroxylase activities alters vitamin E status in tocopherol supplemented mice and reveals extra-hepatic vitamin E metabolism.

CYP4F2 CYP4F12 CYP4F11

1.31e-065178322969154
Pubmed

Rescue of pituitary function in a mouse model of isolated growth hormone deficiency type II by RNA interference.

GH1 CSH1 CSH2

1.31e-065178318006625
Pubmed

AMBRA1 Controls Regulatory T-Cell Differentiation and Homeostasis Upstream of the FOXO3-FOXP3 Axis.

FOXO3 AMBRA1 FOXP3

1.31e-065178330513302
Pubmed

Growth hormone prevents the development of autoimmune diabetes.

GH1 CSH1 CSH2

1.31e-065178324218587
Pubmed

Body composition of inactivated growth hormone (oMt1a-oGH) transgenic mice: generation of an obese phenotype.

GH1 CSH1 CSH2

1.31e-06517839546108
Pubmed

Transgene transmission to progeny by oMt1a-oGH transgenic mice.

GH1 CSH1 CSH2

1.31e-065178316201410
Pubmed

Genes that prolong life: relationships of growth hormone and growth to aging and life span.

GH1 CSH1 CSH2

1.31e-065178311487592
Pubmed

Overexpressed growth hormone (GH) synergistically promotes carcinogen-initiated liver tumour growth by promoting cellular proliferation in emerging hepatocellular neoplasms in female and male GH-transgenic mice.

GH1 CSH1 CSH2

1.31e-065178311318985
Pubmed

Identification of the glomerular podocyte as a target for growth hormone action.

GH1 CSH1 CSH2

1.31e-065178317272398
Pubmed

Glucose homeostasis and insulin sensitivity in growth hormone-transgenic mice: a cross-sectional analysis.

GH1 CSH1 CSH2

1.31e-065178320707609
Pubmed

Cytochrome P4504f, a potential therapeutic target limiting neuroinflammation.

CYP4F2 CYP4F12 CYP4F11

1.31e-065178321466787
Pubmed

Induction of mammary adenocarcinomas in metallothionein promoter-human growth hormone transgenic mice.

GH1 CSH1 CSH2

1.31e-06517831874564
Pubmed

Growth Hormone Deficiency and Excess Alter the Gut Microbiome in Adult Male Mice.

GH1 CSH1 CSH2

1.31e-065178332100023
Pubmed

Transgenic mice expressing bovine GH develop arthritic disorder and self-antibodies.

GH1 CSH1 CSH2

1.31e-065178310810296
Pubmed

Somatotropin transgenic mice have reduced jejunal active glucose transport rates.

GH1 CSH1 CSH2

1.31e-06517837965203
Pubmed

Adipocytokines and the regulation of lipid metabolism in growth hormone transgenic and calorie-restricted mice.

GH1 CSH1 CSH2

1.31e-065178317347312
Pubmed

Pleiotropic effects of growth hormone signaling in aging.

GH1 CSH1 CSH2

1.31e-065178321852148
Pubmed

Body composition, bone mass and microstructural analysis in GH-transgenic mice reveals that skeletal changes are specific to bone compartment and gender.

GH1 CSH1 CSH2

1.31e-065178312175649
Pubmed

Transgenic mice reveal novel activities of growth hormone in wound repair, angiogenesis, and myofibroblast differentiation.

GH1 CSH1 CSH2

1.31e-065178315070902
Pubmed

A novel missense mutation in the mouse growth hormone gene causes semidominant dwarfism, hyperghrelinemia, and obesity.

GH1 CSH1 CSH2

1.31e-065178314726450
Pubmed

UV photodegradation of murine growth hormone: chemical analysis and immunogenicity consequences.

GH1 CSH1 CSH2

1.31e-065178324758742
Pubmed

Consequences of overexpression of growth hormone in transgenic mice on liver cytochrome P450 enzymes.

GH1 CSH1 CSH2

1.31e-065178310076541
Pubmed

Overgrowth of skin in growth hormone transgenic mice depends on the presence of male gonads.

GH1 CSH1 CSH2

1.31e-065178310594738
Pubmed

Hypoxia and cytoplasmic alkalinization upregulate growth hormone expression in lymphocytes.

GH1 CSH1 CSH2

1.31e-065178323639351
Pubmed

Pituitary growth hormone network responses are sexually dimorphic and regulated by gonadal steroids in adulthood.

GH1 CSH1 CSH2

1.31e-065178321098290
Pubmed

Age-related changes in body composition of bovine growth hormone transgenic mice.

GH1 CSH1 CSH2

1.31e-065178318948397
Pubmed

Heterogeneous growth hormone (GH) gene mutations in familial GH deficiency.

GH1 CSH1 CSH2

1.31e-06517838496314
Pubmed

Exploring endocrine GH pattern in mice using rank plot analysis and random blood samples.

GH1 CSH1 CSH2

1.31e-065178321045135
Pubmed

Analysis of gender difference of cardiac risk biomarkers using hGH-transgenic mice.

GH1 CSH1 CSH2

1.31e-065178316508206
Pubmed

Growth hormone overexpression in the central nervous system results in hyperphagia-induced obesity associated with insulin resistance and dyslipidemia.

GH1 CSH1 CSH2

1.31e-065178315616010
Pubmed

Nitric oxide stimulates embryonic somatotroph differentiation and growth hormone mRNA and protein expression through a cyclic guanosine monophosphate-independent mechanism.

GH1 CSH1 CSH2

1.31e-065178319019400
Pubmed

The Effects of 20-kDa Human Placental GH in Male and Female GH-deficient Mice: An Improved Human GH?

GH1 CSH1 CSH2

1.31e-065178332556100
Pubmed

High frequency of mammary adenocarcinomas in metallothionein promoter-human growth hormone transgenic mice created from two different strains of mice.

GH1 CSH1 CSH2

1.31e-06517831525063
Pubmed

Obesity and elevated plasma leptin concentration in oMT1A-o growth hormone transgenic mice.

GH1 CSH1 CSH2

1.31e-065178311346667
Pubmed

Cardiac contractile function is enhanced in isolated ventricular myocytes from growth hormone transgenic mice.

GH1 CSH1 CSH2

1.31e-065178312010633
Pubmed

Developmentally regulated activation of a SINE B2 repeat as a domain boundary in organogenesis.

GH1 CSH1 CSH2

1.31e-065178317626886
Pubmed

Regulation of rapid signal transducer and activator of transcription-5 phosphorylation in the resting cells of the growth plate and in the liver by growth hormone and feeding.

GH1 CSH1 CSH2

1.31e-065178319359380
Pubmed

Growth hormone stimulates the selective trafficking of thymic CD4+CD8- emigrants to peripheral lymphoid organs.

GH1 CSH1 CSH2

1.31e-065178315316240
Pubmed

Involvement of insulin-like growth factor-1 in the effect of caloric restriction: regulation of plasma adiponectin and leptin.

GH1 CSH1 CSH2

1.31e-065178317301034
Pubmed

Growth hormone action in the developing neural retina: a proteomic analysis.

GH1 CSH1 CSH2

1.31e-065178318203262
Pubmed

Assignment of the porcine growth hormone gene to chromosome 12.

GH1 CSH1 CSH2

1.31e-06517832249485
Pubmed

Growth hormone stimulates adipogenesis of 3T3-L1 cells through activation of the Stat5A/5B-PPARgamma pathway.

GH1 CSH1 CSH2

1.31e-065178317242167
Pubmed

A single injection of double-stranded adeno-associated viral vector expressing GH normalizes growth in GH-deficient mice.

GH1 CSH1 CSH2

1.31e-065178318180319
Pubmed

Cloning and characterisation of the GH gene from the common dolphin (Delphinus delphis).

GH1 CSH1 CSH2

1.31e-065178312225773
Pubmed

The related genes encoding growth hormone and prolactin have been dispersed to chromosomes 10 and 17 in the rat.

GH1 CSH1 CSH2

1.31e-06517833780533
Pubmed

High, persistent hepatocellular proliferation and apoptosis precede hepatocarcinogenesis in growth hormone transgenic mice.

GH1 CSH1 CSH2

1.31e-065178310395045
Pubmed

Effect of genetic background on growth of mice hemizygous for wild-type or dwarf mutated bovine growth hormone transgenes.

GH1 CSH1 CSH2

1.31e-065178324190208
Pubmed

Brief report: short stature caused by a mutant growth hormone.

GH1 CSH1 CSH2

1.31e-06517838552145
Pubmed

Promotion of Joint Degeneration and Chondrocyte Metabolic Dysfunction by Excessive Growth Hormone in Mice.

GH1 CSH1 CSH2

1.31e-065178336762426
Pubmed

High molecular weight isoforms of growth hormone in cells of the immune system.

GH1 CSH1 CSH2

1.31e-065178321741628
Pubmed

Structure of the growth hormone-encoding gene and its promoter in mice.

GH1 CSH1 CSH2

1.31e-06517838647448
Pubmed

Thiol-Disulfide Exchange in Human Growth Hormone.

GH1 CSH1 CSH2

1.31e-065178326887678
Pubmed

The role of growth hormone in fetal mouse reproductive tract differentiation.

GH1 CSH1 CSH2

1.31e-06517838756530
Pubmed

GH Knockout Mice Have Increased Subcutaneous Adipose Tissue With Decreased Fibrosis and Enhanced Insulin Sensitivity.

GH1 CSH1 CSH2

1.31e-065178331099824
Pubmed

Hot spots for growth hormone gene deletions in homologous regions outside of Alu repeats.

GH1 CSH1 CSH2

1.31e-06517831980158
Pubmed

Vitamin D3 cannot revert desensitization of growth hormone (GH)-induced STAT5-signaling in GH-overexpressing mice non-calcemic tissues.

GH1 CSH1 CSH2

1.31e-065178317881271
Pubmed

Neural growth hormone implicated in body weight sex differences.

GH1 CSH1 CSH2

1.31e-065178323861378
Pubmed

Growth hormone increases low-density lipoprotein receptor and HMG-CoA reductase mRNA expression in mesangial cells.

GH1 CSH1 CSH2

1.31e-065178312759574
Pubmed

Growth hormone production and action in N1E-115 neuroblastoma cells.

GH1 CSH1 CSH2

1.31e-065178319301152
Pubmed

Adipocyte insensitivity to insulin in growth hormone-transgenic mice.

GH1 CSH1 CSH2

1.31e-065178311350075
Pubmed

Transgenic mice overexpressing growth hormone (GH) have reduced or increased cardiac apoptosis through activation of multiple GH-dependent or -independent cell death pathways.

GH1 CSH1 CSH2

1.31e-065178318617616
Pubmed

Growth hormone and fertility in oMt1a-oGH transgenic mice.

GH1 CSH1 CSH2

1.31e-065178311570960
Pubmed

Promoter shuffling has occurred during the evolution of the vertebrate growth hormone gene.

GH1 CSH1 CSH2

1.31e-065178310974531
Pubmed

Hepatocellular alterations and dysregulation of oncogenic pathways in the liver of transgenic mice overexpressing growth hormone.

GH1 CSH1 CSH2

1.31e-065178323428905
Pubmed

Cardiac expression of adenine nucleotide translocase-1 in transgenic mice overexpressing bovine GH.

GH1 CSH1 CSH2

1.31e-065178317761891
Pubmed

Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development.

GH1 CSH1 CSH2 EP300

1.50e-0617178412464179
Pubmed

Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants.

CYP7A1 CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

1.65e-0670178615128046
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

NCOA3 TTC28 MYCBP2 CENPF IFT74 POLRMT WIZ GTF3C2 KIF15 NR0B1 ZFHX3 S100PBP

1.87e-064181781234709266
Pubmed

Mice lacking the orphan receptor ror1 have distinct skeletal abnormalities and are growth retarded.

ROR1 GH1 CSH1 CSH2

1.92e-0618178420593419
Pubmed

Requirement of FAT and DCHS protocadherins during hypothalamic-pituitary development.

GH1 FAT2 CSH1 CSH2

1.92e-0618178433108146
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

NUGGC CENPF MYO7A POLRMT MEI1 TTC19 KIF15 ZNF408 SEPTIN1 CSPP1 BAG6 TBL2 RIC1

1.93e-064971781336774506
Pubmed

Growth hormone, acting in part through the insulin-like growth factor axis, rescues developmental, but not metabolic, activity in the mammary gland of mice expressing a single allele of the prolactin receptor.

GH1 CSH1 CSH2

2.61e-066178312399427
Pubmed

GH modulates hepatic epidermal growth factor signaling in the mouse.

GH1 CSH1 CSH2

2.61e-066178320032199
Pubmed

Growth inhibition in giant growth hormone transgenic mice by overexpression of insulin-like growth factor-binding protein-2.

GH1 CSH1 CSH2

2.61e-066178311316754
Pubmed

The rise in growth hormone during starvation does not serve to maintain glucose levels or lean mass but is required for appropriate adipose tissue response in female mice.

GH1 CSH1 CSH2

2.61e-066178323150490
Pubmed

Nucleotide sequence of mouse prolactin and growth hormone mRNAs and expression of these mRNAs during pregnancy.

GH1 CSH1 CSH2

2.61e-06617832991252
Pubmed

Third party data gene data set of eutherian growth hormone genes.

GH1 CSH1 CSH2

2.61e-066178326697363
Pubmed

Effects of long-term treatment with growth hormone-releasing peptide-2 in the GHRH knockout mouse.

GH1 CSH1 CSH2

2.61e-066178315985453
Pubmed

Phosphorylation of sterol regulatory element-binding protein (SREBP)-1a links growth hormone action to lipid metabolism in hepatocytes.

GH1 CSH1 CSH2

2.61e-066178320863500
Pubmed

Biological evidence that SOCS-2 can act either as an enhancer or suppressor of growth hormone signaling.

GH1 CSH1 CSH2

2.61e-066178312208853
Pubmed

Involvement of growth hormone as a regulating factor in sex differences of mouse hepatic aldehyde oxidase.

GH1 CSH1 CSH2

2.61e-06617839175714
Pubmed

Disruption of growth hormone signaling retards early stages of prostate carcinogenesis in the C3(1)/T antigen mouse.

GH1 CSH1 CSH2

2.61e-066178316141391
InteractionNOTCH2 interactions

USP53 ZXDC RHBDD1 WNT2 ROR1 ROR2 STYK1 POLRMT ZNF865 SLIT2 ZNF668 RPUSD4 UMODL1 ZNF408 DTX2 ZNF646

7.96e-0742317316int:NOTCH2
InteractionTOP3B interactions

FOXO3 ZXDC PHLDB3 STK36 MYCBP2 CENPF MYO7A POLE POLRMT AMBRA1 PFAS TSC2 APOB CEP192 MLXIP XRCC5 ZNF236 ZNF865 CIT WIZ TRAPPC12 ZNF408 MIB1 LRP4 MAP3K11 DTX2 KLHL14 EP300 SEC23B RIC1

7.70e-06147017330int:TOP3B
Cytoband17q24.2

GH1 CSH1 CSH2

2.15e-0430178317q24.2
Cytoband2q35

STK36 XRCC5 STK16 GMPPA

2.62e-047917842q35
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZXDC ZNF473 ZNF423 ZNF329 ZBTB22 ZNF236 ZNF865 ZFY ZNF711 HINFP ZNF668 WIZ ZNF425 ZNF408 ZNF197 ZFHX3 ZNF582 ZNF646

7.15e-077181161828
GeneFamilyCytochrome P450 family 4

CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

3.21e-063611651003
GeneFamilyGrowth hormone family

GH1 CSH1 CSH2

5.08e-06611631175
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

NCOA3 CLOCK EP300

1.64e-04171163486
GeneFamilyAdenylate cyclases|Deafness associated genes

ADCY3 ADCY8

1.78e-0310116253
GeneFamilyReceptor Tyrosine Kinases|CD molecules

ROR1 ROR2 STYK1

2.14e-03401163321
GeneFamilyKelch like|BTB domain containing

KLHL11 KLHL30 KLHL14

2.46e-03421163617
CoexpressionLI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_DN

CENPF ZNF423 ROR2 MLXIP XRCC5 CIT HINFP GTF3C2 LRP4 MN1

1.83e-0716417710M13108
CoexpressionTESAR_JAK_TARGETS_MOUSE_ES_D3_DN

TBX3 PIWIL2 NR0B1

1.65e-0581773M1766
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

FOXO3 NCOA3 DMXL2 MAN2A1 TTC28 MYCBP2 CENPF ROR1 CLOCK CREB5 SLIT2 RSBN1 GTF3C2 PLPP3 RABGAP1L PIP5K1A ZFHX3 MN1

2.14e-0585617718M4500
ToppCellpdx-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

TICRR CENPF POLE CEP192 CIT NCAPG2 KIF15 FAM83D

1.01e-061901788d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCellCOVID-19-kidney-Proliferating_T_cell|COVID-19 / Disease (COVID-19 only), tissue and cell type

TICRR CENPF CIT NCAPG2 KIF15 NUP210 GRAP2 FAM83D

1.05e-061911788bae388e0e9447d576e68465d73d8313ef6925ffa
ToppCellhuman_hepatoblastoma-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

TICRR CENPF POLE CEP192 CIT NCAPG2 KIF15 FAM83D

1.13e-0619317884b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCellCOVID-19-lung-Proliferative_fibroblast|lung / Disease (COVID-19 only), tissue and cell type

TICRR CENPF ROR2 CIT NCAPG2 SLIT2 KIF15 FAM83D

1.27e-0619617882ce8a787f2731faa913d20342d73041d59468f27
ToppCellCOVID-19-lung-Proliferative_fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

TICRR CENPF ROR2 CIT NCAPG2 SLIT2 KIF15 FAM83D

1.27e-061961788ca91d5e325875e7444809b80fcbd491d8899ea36
ToppCellNS-moderate-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FBXL13 LKAAEAR1 CENPF DZIP1L SYT10 DLEC1 CSPP1

3.33e-061571787410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CENPF KIF15 ARHGEF1 FAM107B GRAP2 SEPTIN1 KLHL14

4.45e-061641787249d8f75a64bce7db52ce0c563f496b9edf602a6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TICRR CENPF WNT2 NDST2 NCAPG2 KIF15 FAM83D

5.01e-061671787bc132b51dec4e8f1cd2b2cd89f83641976e09292
ToppCellnucseq-Immune-Lymphocytic_B|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NCOA3 RHBDD1 NUGGC MYCBP2 RABGAP1L NUP210 KLHL14

9.45e-061841787911658e7bb499c1bbc8419eec8ff88729bc39a75
ToppCellnucseq-Immune-Lymphocytic_B-Lymphocytic_B|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NCOA3 RHBDD1 NUGGC MYCBP2 RABGAP1L NUP210 KLHL14

9.45e-061841787942b58ae7172bb5f97e55b032db9329d161854af
ToppCellControl-T_cells-Cycling_NK/T_cells|Control / group, cell type (main and fine annotations)

TICRR NUGGC CENPF CIT NCAPG2 KIF15 KLHL14

9.78e-0618517879766216b41ee62bbac4caa25cb98ec5627a24075
ToppCellCOVID-19-lung-Plasma_cells_PRDM1/BLIMP_hi|lung / Disease (COVID-19 only), tissue and cell type

TICRR RHBDD1 NUGGC MEI1 KIF15 NUP210 KLHL14

1.01e-05186178766676d9395172de5707e204826a1c9f73b448cca
ToppCelldroplet-Lung-nan-21m-Lymphocytic-Proliferating_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST6GALNAC1 TICRR POLE NCAPG2 KIF15 FAM83D FOXP3

1.09e-05188178761ae7405ab56570409bf35382dc0a038e4137c15
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TICRR CENPF POLE NCAPG2 KIF15 FAM83D FOXP3

1.20e-05191178715dbc5a03bfab8931c0fd385b0f25874736ae874
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-Proliferating_T_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TICRR CENPF POLE NCAPG2 KIF15 FAM83D FOXP3

1.20e-05191178745c15f5ce4a207ac944bed65d45f06c1657d1a6d
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CENPF POLE SOX17 CIT NCAPG2 KIF15 FAM83D

1.33e-0519417873a49c7c86036e09a8cd0114988380d04ad1a26fb
ToppCellBronchus_Control_(B.)-Epithelial-TX-AT2-2|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

TBX3 EVC TEX14 METTL1 LRP4 RIC1 S100PBP

1.33e-0519417875bfc26668fa8f109f2ebc0d5fd98ab5bd219e62c
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HIPK4 DZIP1L TEX14 ZNF865 WIZ AGL

1.34e-051291786cbeeaa554da971ba2e4c4b82c85a1d070a45abb8
ToppCellCOVID-19-T_cells-Cycling_NK/T_cells|COVID-19 / group, cell type (main and fine annotations)

TICRR CENPF CIT NCAPG2 KIF15 NUP210 FAM83D

1.38e-051951787764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CENPF POLE SOX17 CIT NCAPG2 KIF15 FAM83D

1.38e-0519517875790b47b0e028e49b99bda8d6d9e80ac79208cdf
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG|World / Primary Cells by Cluster

CENPF ADGRV1 CREB5 KIF15 PLPP3 NUP210 LRP4

1.47e-05197178761749ccafeb938c310cff1de5ff924a1c794325a
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG-25|World / Primary Cells by Cluster

CENPF ADGRV1 CREB5 KIF15 PLPP3 NUP210 LRP4

1.47e-0519717879d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCellLPS_only-Epithelial_airway-airway_epithelial-Ciliated|LPS_only / Treatment groups by lineage, cell group, cell type

STK36 FBXL13 ARMC3 LKAAEAR1 MYO7A DZIP1L DLEC1

1.52e-0519817876d90b541fde357fbb40f8f7d4e8628a48b679718
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TICRR CENPF POLE EVC CIT NCAPG2 KIF15

1.62e-052001787af3dc76b4507bf4edd265169f5dfbbb8a19eb394
ToppCellLPS_only-Endothelial-Endothelial-FOXM1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TICRR CENPF POLE CIT NCAPG2 KIF15

1.66e-0513417864d8f7ddad02fe76a614771e115ebb8e04623ba85
ToppCellControl-Mast_cells-Transitioning_MDM|Control / group, cell type (main and fine annotations)

PHLDB3 CDK15 WNT2 LRP4 FAM83D KLHL14

4.67e-0516117865807ee48f871a3eb24ebf78fd107cf5f2a4ec846
ToppCelldroplet-Fat-SCAT-30m-Lymphocytic-B_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUGGC KLHL30 RABGAP1L FAM107B SEPTIN1 KLHL14

5.54e-0516617864b31d2755108b2815316411a38bfb11fd30ef98a
ToppCelldroplet-Fat-SCAT-30m-Lymphocytic-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUGGC KLHL30 RABGAP1L FAM107B SEPTIN1 KLHL14

5.54e-05166178667370c49d7aedcb4eca802095f06b30f6bbf8919
ToppCelldroplet-Fat-SCAT-30m-Lymphocytic|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUGGC KLHL30 RABGAP1L FAM107B SEPTIN1 KLHL14

5.54e-0516617867f4e5976ede6478636aa567d6fc2b56ff7295fb8
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

ROR1 ADGRV1 ZFY NCOA7 PRKCZ USP54

6.32e-051701786e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCellfacs-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CEP192 ZNF865 TAB3 SEPTIN1 METTL22 FOXP3

6.53e-051711786f1fdc0ec3399ed6955976d02be7e5fc329a64276
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZNF473 CENPF STYK1 KIF15 KLHL30 SEPTIN1

6.53e-051711786846a9acfff0bf0a9baf65dc07b7d7a9217ed6598
ToppCellCOVID-19_Mild-Neu_2|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients

USP53 CLOCK ZFY RPUSD4 ZNF408 HEATR5B

6.74e-051721786f5fd08b42c002d4693646b27e7b708eceb49524f
ToppCelldroplet-Lung-nan-18m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF473 CENPF CIT KLHL11 KIF15 NUP210

6.74e-051721786e495efd25aec60b97ac2b5aa861651bd73174a17
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

USP53 FAM107B SEPTIN1 PRKCZ DCAF11 FOXP3

6.74e-05172178630f4979abf0218618a56afb06aa6afc23ad838ec
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC28 DZIP1L ROR1 TEX14 FADS3 ZFHX3

6.96e-0517317862415b6ff49f334da570577d4e93484d024a3dbd5
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC28 DZIP1L ROR1 TEX14 FADS3 ZFHX3

6.96e-0517317862acd0693a2dfe04e3c1b2125ea63efe92d13150b
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ST6GALNAC1 CENPF ADGRV1 CIT KIF15 NUP210

7.19e-0517417867b2f35add804981c7d588a996bdbca6ec11a1ca5
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TICRR CENPF CIT NCAPG2 KIF15 SNX32

7.66e-0517617868813c01ea080f373fe3970c5e1ba4c2dca0f7f02
ToppCellfacs-Skin-Anagen-24m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TICRR CENPF MYO7A CIT KIF15 BBS7

7.90e-0517717868a0f0fbb06cdacb99a3fdba0da3e0494b891db4f
ToppCellfacs-Skin-Anagen-24m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TICRR CENPF MYO7A CIT KIF15 BBS7

7.90e-051771786e9d7682517fb30fd2ad535d59779d718a7024c13
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-1|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NCOA3 ZNF473 GH1 ZNF711 ZPBP2 KLHL14

8.15e-051781786812e261d9cbdc74fafe3c5c3422151c1cfacb22d
ToppCell10x3'2.3-week_12-13-Lymphocytic_B-B_lineage-immature_B_cell|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

USP53 CEP192 FAM107B NCOA7 KLHL14 HECA

9.21e-051821786ab78df9de3878a6d67106a40094c893601de8076
ToppCellCOVID-19-B_cells-Plasma_cells|COVID-19 / group, cell type (main and fine annotations)

NCOA3 RHBDD1 NUGGC MEI1 NUP210 KLHL14

9.49e-051831786130c109f63a5e3c8f83cb96e32f4addf513b6415
ToppCellCOVID-19-B_cells|COVID-19 / group, cell type (main and fine annotations)

NCOA3 RHBDD1 NUGGC MEI1 NUP210 KLHL14

9.49e-0518317862c016bb59f131a0e821853b085289a3583f0a729
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

TTC28 MYCBP2 ROR1 KIAA1586 SLIT2 BHMT2

9.78e-05184178667164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating-T_cells_proliferating_L.1.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TICRR CENPF MYO7A MEI1 KIF15 NUP210

9.78e-0518417868260e688ec42a1374727bc85dceb7edd19a8b662
ToppCellnucseq-Immune-Lymphocytic_B-Lymphocytic_B-Plasma|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NCOA3 RHBDD1 NUGGC MEI1 RABGAP1L RIC1

1.01e-0418517863b77bc49cd3740acc025e162a36282ac09e12198
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIPK4 CDK15 SOX17 CASP12 FGD5 MN1

1.01e-041851786f98af3146ec2f44c30d31a662fb9c4fa3ca4f706
ToppCell343B-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ZNF329 AMBRA1 HEATR5A CEP192 NCOA7 CPEB1

1.01e-0418517861b8e3ddb91797f84e4b15d2457b0c008e5be50db
ToppCell343B-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ZNF329 AMBRA1 HEATR5A CEP192 NCOA7 CPEB1

1.01e-04185178602cbf492bc40abebaa93a3a208888afae72fbe06
ToppCell343B-Fibroblasts-Fibroblast-E-|343B / Donor, Lineage, Cell class and subclass (all cells)

ZNF423 ZNF329 CEP192 ADCY3 BHMT2 CPEB1

1.04e-0418617861bac7825c2fe3e6cdff65026b09b9ccaa40fa27f
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TICRR CENPF CNTRL CIT RSBN1 KIF15

1.04e-04186178615ab6666748a641226e42e6ca6eeaf186a501c95
ToppCell343B-Fibroblasts-Fibroblast-E|343B / Donor, Lineage, Cell class and subclass (all cells)

ZNF423 ZNF329 CEP192 ADCY3 BHMT2 CPEB1

1.04e-04186178659db239f1864a5d4f1570c93219dbd7ac5b6db35
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TICRR CENPF CNTRL CIT RSBN1 KIF15

1.04e-0418617864ed1b97e2552f3c4134f25665d7513498ffac16c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TICRR CENPF ROR2 NCAPG2 KIF15 FAM83D

1.07e-041871786e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TICRR CENPF ROR2 NCAPG2 KIF15 FAM83D

1.07e-041871786cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCellEpithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|World / Lineage, Cell type, age group and donor

ADGRV1 CIT DUOXA1 PRKCZ MAP3K13 USP54

1.07e-04187178681cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCell343B-Lymphocytic-ILC-ILC-1|343B / Donor, Lineage, Cell class and subclass (all cells)

GHDC MYO7A HEATR5A ADCY3 AGL GRAP2

1.10e-0418817868f6b45ad82bde65e044d17f0edbc3db90d457915
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_B-plasmablast-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

NUGGC CENPF SAMD7 KIF15 ST6GALNAC4 KLHL14

1.10e-041881786ecba5d06cbf3254448255a2aeefffe711f43310e
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CENPF ROR1 CIT NCAPG2 KIF15 FAM83D

1.10e-04188178695d0a796d62ce6d121e2028c378faffc14b35275
ToppCellCOVID-19-lung-Plasma_cells_PRDM1/BLIMP_hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

TICRR NUGGC MEI1 KIF15 NUP210 KLHL14

1.10e-041881786567b08514d9d84cbb40f9b7a679eec304f023428
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_B-plasmablast|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

NUGGC CENPF SAMD7 KIF15 ST6GALNAC4 KLHL14

1.10e-0418817868cf135da4d1d2500755d2809d60b41509af9fa8b
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|368C / Donor, Lineage, Cell class and subclass (all cells)

MEI1 RPUSD4 GTF3C2 DCLRE1C NUP210 ELMOD3

1.13e-041891786610d7cc1fc923dbd67d3b71f94d529a658982f87
ToppCellE15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TBX3 CENPF WNT2 CIT KIF15 FAM83D

1.13e-041891786d049f33115610bda4489968759f754730698b9cd
ToppCellControl-Endothelial-Endothelial-FOXM1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TICRR CENPF POLE CIT NCAPG2 KIF15

1.13e-0418917861e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TICRR CENPF NCAPG2 FAT2 KIF15 AGL

1.20e-0419117860f9443da0f73d07456142fae08b2dc92a5b7b592
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TICRR CENPF CIT NCAPG2 KIF15 FAM83D

1.20e-0419117860ba5b112a82e489f5a21966f78a403a7436ce73b
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TICRR CENPF CIT NCAPG2 KIF15 FAM83D

1.23e-04192178627723f4e320e49d4a3daafa2d8d3946ff79fab64
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TICRR CENPF CIT NCAPG2 KIF15 FAM83D

1.23e-0419217860a54c79dcfdeb99e3b512d42b22359618cfd17e9
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TICRR CENPF CIT NCAPG2 KIF15 FAM83D

1.23e-041921786026f3e38970bea1e6e8d76a4e2becdfb8484b2ff
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

ROR1 ADGRV1 DUOXA1 PRKCZ MAP3K13 USP54

1.23e-041921786efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellControl-Lymphoid-Proliferating_CD4_T_cells|Control / Condition, Lineage and Cell class

TICRR CENPF CIT NCAPG2 KIF15 FAM83D

1.27e-04193178633d409d6ed1c606337248587ad997ac5f67f081d
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

MAN2A1 GOSR1 HEATR5A ADGRV1 CLOCK KLHL11

1.27e-041931786abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c14-MKI67-CCL5_h|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TICRR CENPF CIT NCAPG2 KIF15 FAM83D

1.27e-041931786cf680afddc08b6481f1b3eee9c57acfaebeac6f0
ToppCellPCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TICRR CENPF ADGRV1 CIT KIF15 FAM83D

1.31e-041941786c197e4acbff42a9f0410b6801c2bfcf6160aefc1
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TTC28 WNT2 ZNF423 ROR1 ROR2 SLIT2

1.31e-041941786b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCellnucseq-Epithelial-Epithelial_Alveolar|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ROR1 ADGRV1 DUOXA1 NCOA7 PRKCZ USP54

1.31e-04194178653f3e49e91b1096f3226010e2de767efb490dfe4
ToppCellLA-02._Fibroblast_II|LA / Chamber and Cluster_Paper

USP53 FOXO3 TTC28 CREB5 SLIT2 ZFHX3

1.31e-041941786234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Cervical_Squamous_Cell_Carcinoma-3|TCGA-Cervix / Sample_Type by Project: Shred V9

ZXDC TICRR FAT2 ELMOD3 RIC1

1.31e-0412217851ed865f0ecfe304fb86313ff51c04e9052357270
ToppCellDividing_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

TICRR CENPF CIT NCAPG2 KIF15 FAM83D

1.34e-04195178679ee423df85aa1631b7bdea74eacaf826dfc4a2c
ToppCelldroplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DMXL2 CENPF MYO7A NCAPG2 KIF15 FAM83D

1.34e-041951786c1435e61e4f0cf457f26ae436936048932ceb0db
ToppCellDividing_cells-Dividing_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

TICRR CENPF CIT NCAPG2 KIF15 FAM83D

1.34e-04195178619829760dfcc0edafd2a2bd80f424a45d039af1f
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TTC28 WNT2 ZNF423 ROR1 ROR2 SLIT2

1.34e-0419517860e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TICRR CENPF CIT NCAPG2 KIF15 FAM83D

1.34e-041951786926eb3fc5d028be936885bea0654a77db3107234
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ROR1 ADGRV1 DUOXA1 NCOA7 PRKCZ USP54

1.34e-0419517869406866f99555198a9be311fbd65751b70f35446
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TICRR CENPF CIT NCAPG2 KIF15 FAM83D

1.34e-0419517861a5e814e12fe37287dbfc58189e1958e2c76b5da
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TBX3 CENPF SOX17 CIT KIF15 FAM83D

1.34e-041951786a838bddeed487154791b69d27a68673783ff63c0
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

TTC28 ROR1 AMBRA1 ADGRV1 RABGAP1L LRP4

1.38e-041961786ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CENPF SOX17 CIT NCAPG2 KIF15 FAM83D

1.38e-04196178620383d576708b7e4bfce3e9fe40548cce496e3cb
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TICRR CENPF CIT NCAPG2 KIF15 FAM83D

1.38e-0419617861964c5003a0cb84539850a7cfe3bbb0e23a61d2d
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TICRR CENPF CIT NCAPG2 KIF15 FAM83D

1.38e-04196178673f951f7712e0aa3323676b9a4b7944d21d347c4
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CENPF SOX17 CIT NCAPG2 KIF15 FAM83D

1.38e-0419617860644bd14a944b9c9759a295dfdd5e67a4775f20a
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

HEATR5A ADGRV1 AK8 FADS3 RGS17 USP54

1.42e-041971786b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCellMild_COVID-19-T/NK-proliferating_T/NK|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

TICRR CENPF CIT NCAPG2 KIF15 FAM83D

1.42e-0419717865fd52fba2cb6fa67377f873da2ff6ce9c83b0591
ToppCellBAL-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TICRR CENPF CIT NCAPG2 KIF15 FAM83D

1.42e-041971786d7a9296092153cf66426911fecd810f0c1ef978e
ToppCellBAL-Mild-Lymphocyte-T/NK-Other_T|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TICRR CENPF CIT NCAPG2 KIF15 FAM83D

1.42e-041971786dcff23240bb7cb652d7426b29355aa74442ef6fc
ToppCelldistal-1-Hematologic-Basophil/Mast_1|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CDK15 NDST2 GRAP2 LRP4 RGS17 ATP2B2

1.42e-041971786e33752427eefeacbbc538e1b35f37194bdabfc40
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CENPF SOX17 CIT NCAPG2 KIF15 FAM83D

1.42e-041971786a41420d4b6d502c2f594c054c7efbb5d4eac83ff
ToppCellBAL-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

TICRR CENPF CIT NCAPG2 KIF15 FAM83D

1.42e-041971786434a5686a103bb766e0d80038413f0e12ea3981a
Drugtienilic acid

CYP7A1 CYP4F2 ADCY3 ADCY8 CYP4A22 CYP4F3 CYP4F12 CYP4F11

6.61e-07931778CID000038409
Drugmephenytoin

CYP7A1 CYP4F2 CIT CYP4A22 CYP4F3 CYP4F12 CYP4F11

5.69e-06881777CID000004060
Drugaminoglutethimide

CYP7A1 TECR CYP4F2 CYP4A22 AGL CYP4F3 CYP4F12 CYP4F11

1.21e-051371778CID000002145
Drugpropoxyphene

CYP7A1 CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

1.37e-05671776CID000010100
DrugSparteinum

TBX3 CYP7A1 CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

1.42e-051011777CID000003966
DrugC 15

WNT2 GH1 CSH1

1.58e-0571773CID003014700
Drugcarteolol

CYP7A1 CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

2.07e-05721776CID000002583
DrugDimenhydrinate [523-87-5]; Down 200; 8.6uM; PC3; HT_HG-U133A

ZXDC ZNF473 GOSR1 EVC TSC2 ZNF668 GTF3C2 ZNF408 NUP210

2.58e-0519817796352_DN
Drugtolbutamide

CYP7A1 CYP4F2 ADCY3 ADCY8 CYP4A22 AGL CYP4F3 CYP4F12 CYP4F11

2.58e-051981779CID000005505
DrugBisoprolol fumarate; Down 200; 9uM; HL60; HT_HG-U133A

GOSR1 AMBRA1 MLXIP HINFP WIZ ARHGEF1 NUP210 ST6GALNAC4 CSPP1

2.58e-0519817791287_DN
Drughalothane

CYP7A1 CYP4F2 ADCY3 ADCY8 CHRNB2 CYP4A22 CYP4F3 CYP4F12 PRKCZ CYP4F11 ATP2B2

3.69e-0531417711CID000003562
Drugtrimipramine

CYP7A1 CYP4F2 CYP4A22 CYP4F3 CYP4F12 CYP4F11

3.78e-05801776CID000005584
Diseaseisolated growth hormone deficiency type II (implicated_via_orthology)

GH1 CSH1 CSH2

1.96e-0651733DOID:0060872 (implicated_via_orthology)
Diseaseisolated growth hormone deficiency (implicated_via_orthology)

GH1 CSH1 CSH2

6.81e-0671733DOID:0060870 (implicated_via_orthology)
Diseaseautosomal dominant nonsyndromic deafness (is_implicated_in)

ELMOD3 ATOH1 ATP2B2

3.16e-05111733DOID:0050564 (is_implicated_in)
DiseaseCiliopathies

MYO7A ZNF423 EVC TSC2 ADGRV1 BBS7

4.82e-051101736C4277690
DiseasePolydactyly

TBX3 CENPF EVC BBS7 LRP4 CSPP1

6.80e-051171736C0152427
Diseasecongenital hypothyroidism (biomarker_via_orthology)

GH1 CSH1 CSH2

6.88e-05141733DOID:0050328 (biomarker_via_orthology)
Diseaseheight-adjusted body mass index

ADCY3 ADCY8

1.02e-0431732EFO_0005851
DiseaseAdenocarcinoma of large intestine

POLE ROR1 ROR2 PRKCZ EP300

2.60e-04961735C1319315
Diseasecigarettes per day measurement

ZNF423 AMBRA1 ADCY3 CREB5 ADCY8 CHRNB2 ZNF668 ZNF408 RABGAP1L TBL2

2.78e-0443817310EFO_0006525
Diseaseosteoporosis (biomarker_via_orthology)

GH1 CSH1 CSH2

2.81e-04221733DOID:11476 (biomarker_via_orthology)
Diseasehypertension (biomarker_via_orthology)

CYP4F2 CLOCK CYP4A22 CYP4F12 CYP4F11 EP300 FOXP3

4.02e-042271737DOID:10763 (biomarker_via_orthology)
Diseasesuicidal ideation

NUGGC AREL1 ZFHX3

6.47e-04291733EFO_0004320
DiseaseCOVID-19, obesity

ADCY3 ADCY8

7.04e-0471732EFO_0001073, MONDO_0100096
Diseaseresponse to ketamine

EVC SYT10 SLIT2 ZFHX3

7.33e-04691734EFO_0009748
Diseaselevel of Triacylglycerol (49:2) in blood serum

GTF3C2 ADGRD2

9.35e-0481732OBA_2045162
Diseasehexadecenedioate (C16:1-DC) measurement

CYP4F2 CYP4F11

1.20e-0391732EFO_0800562
Diseaseglioblastoma (implicated_via_orthology)

POLE CPEB1

1.20e-0391732DOID:3068 (implicated_via_orthology)
DiseaseNonsyndromic Deafness

MYO7A ROR1 ADGRV1 ELMOD3

1.34e-03811734C3711374
DiseaseObesity

FOXO3 ADCY3 GH1 BBS7 ZFHX3 EP300

1.36e-032051736C0028754
DiseaseOdontome

TBX3 LRP4

1.49e-03101732C0524730
DiseaseTooth Abnormalities

TBX3 LRP4

1.49e-03101732C0040427
Diseasetype 1 diabetes mellitus (implicated_via_orthology)

GH1 CSH1 CSH2

1.55e-03391733DOID:9744 (implicated_via_orthology)
DiseaseMalignant neoplasm of breast

NCOA3 TPTE TBX3 CENPF ROR1 ZNF668 TRAPPC12 SNX32 FGD5 DLEC1 MAP3K13 USP54 EP300 ZNF646 FOXP3

1.71e-03107417315C0006142
Diseasetype 2 diabetes mellitus (biomarker_via_orthology)

GH1 CASP12 CSH1 CSH2 PRKCZ

1.79e-031471735DOID:9352 (biomarker_via_orthology)
DiseaseNeoplasm of uncertain or unknown behavior of breast

TBX3 MAP3K13 EP300

1.79e-03411733C0496956
DiseaseBreast adenocarcinoma

TBX3 MAP3K13 EP300

1.79e-03411733C0858252
Diseaselysophosphatidylcholine 20:2 measurement

FOXO3 FADS3

1.82e-03111732EFO_0021458
Diseasenasopharyngeal neoplasm

RHBDD1 ADCY3 CREB5 ADCY8 ZFHX3

2.01e-031511735EFO_0004252
Diseaselevel of Ceramide (d42:2) in blood serum

CYP7A1 APOB

2.17e-03121732OBA_2045186
Diseasecortical thickness

FOXO3 FBXL13 MYCBP2 ZNF423 ROR1 ADGRV1 CLOCK SLIT2 UMODL1 FAM107B LRP4 DLEC1 PRKCZ ATOH1 CPEB1

2.41e-03111317315EFO_0004840
Diseaseamenorrhea, response to antineoplastic agent

APOB ADCY8

3.41e-03151732EFO_0010269, GO_0097327
Diseasedecreased susceptibility to hepatitis C infection

OFCC1 ATOH1

3.89e-03161732EFO_0010101
DiseaseDiabetic Angiopathies

ADCY3 ADCY8

3.89e-03161732C0011875
DiseaseMicroangiopathy, Diabetic

ADCY3 ADCY8

3.89e-03161732C0025945
Diseaseheart disease (biomarker_via_orthology)

CASP12 EP300

4.39e-03171732DOID:114 (biomarker_via_orthology)
DiseaseBreast Carcinoma

NCOA3 TBX3 CENPF ROR1 SNX32 FGD5 MAP3K13 EP300 FOXP3

4.64e-035381739C0678222
Diseaseandrostenedione measurement, estrone measurement

ARMC3 RPUSD4

4.92e-03181732EFO_0007970, EFO_0007972
Diseasebrain measurement, neuroimaging measurement

FOXO3 ROR1 SLIT2 ARHGEF1 FAM107B MIB1 ZFHX3 PRKCZ ATOH1

5.34e-035501739EFO_0004346, EFO_0004464
Diseasehydrocephalus (implicated_via_orthology)

STK36 AK8

5.47e-03191732DOID:10908 (implicated_via_orthology)
Diseasesexual dimorphism measurement

FOXO3 GOSR1 TSC2 APOB MLXIP ADCY3 CREB5 ADCY8 GH1 CSH1 SNX32 SLIT1 MAP3K11 ZFHX3

5.77e-03110617314EFO_0021796

Protein segments in the cluster

PeptideGeneStartEntry
QVDPRLLNHMRLLHS

UMODL1

186

Q5DID0
HNENMLRNILPSHVA

ADCY8

946

P40145
NHNTMPSQFRDILRR

EP300

2171

Q09472
RTHFIDHDRPMNTLT

BBS7

496

Q8IWZ6
HVRMLRVLHDLFFQP

ARHGEF1

431

Q92888
QLRNDHMNLRGHTPL

CNTRL

421

Q7Z7A1
LPMAQEIFRLSRHHI

ELMOD3

231

Q96FG2
DVVMLLHGHFQPLQR

BAG6

766

P46379
IRGLPLHHRMFATQT

BOLA3

16

Q53S33
GIFPTTVHLQQHMRR

ADGRV1

1306

Q8WXG9
QMIRLHVQRLFGFHS

ADGRV1

5021

Q8WXG9
QNHDIMHAIISPLRS

ARMC3

436

Q5W041
SELFRLAAHPLNNRM

DMXL2

2366

Q8TDJ6
RLEMNSNPLHFRVEN

DNHD1

4626

Q96M86
RTPLLHNFLHMLSSR

AMBRA1

236

Q9C0C7
LLHPSTEHMVAQVFR

AMBRA1

966

Q9C0C7
METALRQFAAHPEHQ

CASP12

146

Q6UXS9
RMHHNIPHRFNVGLN

CIT

1356

O14578
RTSIHNFMAHPEFRI

ATP2B2

1161

Q01814
PFINSHEIRSMILHL

CPXCR1

141

Q8N123
LQVLHPMDAAQRSQH

MKRN4P

276

Q13434
PEHTMSHINFRLALI

PGBD4

476

Q96DM1
LMHRDSFPRFLNSQI

RGS17

181

Q9UGC6
HSFLSQRIMLPFHIN

RIC1

761

Q4ADV7
HLPSHAQDMLDGLQR

KLHL30

11

Q0D2K2
MNATFLRGHIQRRHA

DZIP1L

176

Q8IYY4
RIMARHLHPIQTSFQ

NUP210

1556

Q8TEM1
IHPDIAHMERLLQQA

PHLDB3

451

Q6NSJ2
LSSLLHLHNRQRQPM

CREB5

161

Q02930
IFSAVRLDTHLHNPM

OR6K3

61

Q8NGY3
VPLTIQLTHQFFHRM

KIAA0100

2011

Q14667
NAALMHTLQRHRDIL

GOSR1

101

O95249
SERHMHVQLQLDNLR

KIF15

836

Q9NS87
AVTENMRVPHFLQDH

KIAA0895

481

Q8NCT3
LNRAGLSHMLIQRVH

MAN2A1

301

Q16706
LQDRPHFMHQLSTVD

FOXP3

96

Q9BZS1
ALRHPFVSMQQLRSA

HIPK4

341

Q8NE63
SHDLPRRHSMDRQNS

HECA

236

Q9UBI9
RNMYHQFDRTLHPRQ

MTMR6

496

Q9Y217
TMRAVRRHLFPQHSA

DTX2

91

Q86UW9
PLSRLFDHAMLQAHR

CSH2

31

P0DML3
MIQHLHRDNDNVPRI

AK8

46

Q96MA6
FMIANINHHRPQFLE

FAT2

1436

Q9NYQ8
IQHMNLRLLSDRNHE

KIAA1586

611

Q9HCI6
LNRMHRQNIDAYHNP

CSPP1

691

Q1MSJ5
AQKHSFPRMLHQRER

DCAF11

126

Q8TEB1
RQFHFAGIRSRLNHM

FAM83D

531

Q9H4H8
LQHLNLDFHGAVMRA

FGD5

911

Q6ZNL6
MPRVLRHRHLAQCLQ

GHDC

511

Q8N2G8
DPRMNLFHISIHQQQ

MYCLP1

191

P12525
LAAMLPAQRHRHLLF

LKAAEAR1

51

Q8TD35
LRALFHMNILLPDSH

NLRP5

561

P59047
MPASRSEYHRIQHQL

POLE

676

Q07864
LMSIHNIDHAQREPL

PIP5K1A

326

Q99755
ERLMQEQLPDLHSHF

RABGAP1L

671

Q5R372
HHAALRGNPSAMRVL

MIB1

601

Q86YT6
RHLEQTTHPALMEVF

MEI1

561

Q5TIA1
RMTHQGPHDRFIELN

NR0B1

416

P51843
HLQFRFHPQRMIISR

NPIPB11

586

E5RHQ5
RHDMPDRTLAAHQQK

OFCC1

61

Q8IZS5
NRPSFRQTLMHLDIA

MAP3K13

396

O43283
PRRQQIIHSGHFMVS

MLXIP

71

Q9HAP2
FPLSAMLEAHRRQRH

GMPPA

121

Q96IJ6
LLDHRVPQTDMTFRH

APOB

1211

P04114
LHQERMILSTHRNAF

IFT74

501

Q96LB3
QLHMFAPRHVNLSSL

HEATR5A

1051

Q86XA9
LQQLHMFAPRHVNLS

HEATR5B

1051

Q9P2D3
IHRHALNMRRVPSSQ

KLHL11

691

Q9NVR0
HLMPFRQHCRQSLAS

KLHL14

301

Q9P2G3
EHPDAVRQLHMEFLR

BHMT2

51

Q9H2M3
RNMPEILHHLTTDRN

DCLRE1C

236

Q96SD1
TLPQATMNHRDIARH

CENPF

196

P49454
QRSLLAFDQQPAMHH

CENPF

781

P49454
LHPHNVRLFMFQLLR

CDK15

196

Q96Q40
TSRNHQDLHRELLMN

FAM107B

26

Q9H098
RHRRMLTPAFHFNIL

CYP4F11

146

Q9HBI6
QHRRMLTPAFHNDIL

CYP4A22

141

Q5TCH4
RMQRLAREHGSHPVQ

F8A1;

206

P23610
NLLTHHRRNTSMEPA

C4orf17

226

Q53FE4
RHRRMLTPAFHFNIL

CYP4F12

146

Q9HCS2
RMHGLNHAFDQLRNV

ATOH1

171

Q92858
FDRVNMHNLLIHLVR

CCDC183

101

Q5T5S1
HRQVQDRMVPSAHNR

DNAAF8

296

Q8IYS4
LVTNMLPEHVARHFL

ADCY3

891

O60266
FQRELRQVHMKRPHS

AREL1

446

O15033
RHRRMLTPAFHFNIL

CYP4F2

146

P78329
RTMRLLPRHFHNLQN

FBXL13

286

Q8NEE6
RIHAPRDLQTMHFLA

CEP192

1646

Q8TEP8
AGLPIHMFRTAHNAR

CYP7A1

221

P22680
RHHSPLMRNQKNRDS

CPEB1

551

Q9BZB8
RHRRMLTPAFHFNIL

CYP4F3

146

Q08477
RFLAQFPVHQQMRLH

EVC

861

P57679
LMHRRHTDPVQLQAA

GRAP2

256

O75791
LPSSLRNHMRFRHSE

HINFP

266

Q9BQA5
PLSRLFDHAMLQAHR

CSH1

31

P0DML2
NFQIEHHLFPRMPRH

FADS3

381

Q9Y5Q0
SPHELRDFHSVLQMV

DLEC1

701

Q9Y238
AHRMQPHRLKAFFNQ

DUOXA1

271

Q1HG43
RNMRSHHRFQRLPDF

S100PBP

391

Q96BU1
AQHLRDRVFWLPHNM

POLRMT

786

O00411
VRQEARLFAMLAHPN

MAP3K11

161

Q16584
LQVLHPMDAAQRSQH

MKRN1

241

Q9UHC7
QFEYPIHRLENRSMH

MN1

406

Q10571
RHNLSLHSRFMRVQN

FOXO3

211

O43524
HSLHRLRLEMPNEDQ

RPUSD4

351

Q96CM3
PFMTHQEHSIRRNFL

RSBN1

336

Q5VWQ0
AERLRVQHMQDHPNY

SOX17

121

Q9H6I2
LPNEHLHMSVLRRFA

NUGGC

481

Q68CJ6
RLRLHSFMLPCNHSL

TRIM42

151

Q8IWZ5
GFHLSPEEMRRQRLH

RHBDD1

296

Q8TEB9
SVLHERRSQFPVLHM

TEX14

336

Q8IWB6
RRSQFPVLHMEVIVH

TEX14

341

Q8IWB6
SSVHRHPFLNLNTMR

TBX3

621

O15119
EAQREADMHRLFNHP

STK16

61

O75716
ADMHRLFNHPNILRL

STK16

66

O75716
MNRNRLLHINLGIHS

TAB3

66

Q8N5C8
HFHRSTLRNLQGNPM

SAMD7

151

Q7Z3H4
YHRIVQQRMQHSPDL

FANCL

66

Q9NW38
LRPHSALLENMHIEQ

NCOA7

776

Q8NI08
LSPVDIIDRNNHHNM

PLPP3

296

O14495
LLIHRPSERQDNHGM

PIWIL2

471

Q8TC59
RELLSHHFRQQRVAM

NCOA3

1231

Q9Y6Q9
RMFEQHHPRSFNLNT

TEX53

26

A0A1B0GU33
FRHRPQEAFREALHM

ST6GALNAC1

471

Q9NSC7
FMNHREQALARLRSH

MYCBP2

886

O75592
HLLEHMSQHRRAPGQ

WIZ

281

O95785
FRHEAMLRARLQHPN

ROR2

521

Q01974
SRVAQMHSLFRHLFP

SOWAHD

296

A6NJG2
LYTPNHRHLMVRLNS

METTL22

26

Q9BUU2
RHHFARQDLTQSLIM

SEC23B

606

Q15437
RGLRHPNIVHMLDSF

STK36

56

Q9NRP7
RIQVEHPQMTFGRLH

SSX1

91

Q16384
LLFMQQPRHHCARQR

CHRNB2

346

P17787
VAMTFHLQHRAQSPL

ADGRD2

586

Q7Z7M1
HLPAHEKMVQRRSSF

CLOCK

466

O15516
IQDFMFHGIHLPRRS

NCAPG2

286

Q86XI2
NMLERIHFHIVPSRD

USP53

126

Q70EK8
NQGDLHEFLIMRSPH

ROR1

556

Q01973
NPHHCDFLNLRRMLV

SEPTIN1

261

Q8WYJ6
HLFHGDVAARNILMQ

STYK1

246

Q6J9G0
SDLARQINHPELHMV

TTC19

306

Q6DKK2
HNRVVRIMIDDHNVP

TPTE

296

P56180
QMYLAHEQAPRSAHR

ST6GALNAC4

261

Q9H4F1
QRQLCHRHPDVMRAI

WNT2

51

P09544
GFIQRSSLLMHLRNH

ZNF197

406

O14709
ALLMRHQRCHTEQRP

ZNF865

861

P0CJ78
TVTLEPLAMHQRHFQ

TICRR

321

Q7Z2Z1
HMVRQHSRRQDLLPQ

ZXDC

471

Q2QGD7
DFRQPADLAMHRRVH

ZNF668

316

Q96K58
QLEAMVQQDPRHYLH

TRAPPC12

676

Q8WVT3
ALATLHDRMTEQHFP

PFAS

141

O15067
RNFLSRNRLMITHHA

TLCD3A

111

Q8TBR7
PLANQGSLRNHMRLH

ZNF408

476

Q9H9D4
YPNLMALRNHVRVHC

ZNF646

501

O15015
HLFHNRSVLADQMRL

NDST2

396

P52849
FDNAMLRAHRLHQLA

GH1

36

P01241
LFVHRFSHGTMPLRN

TECR

146

Q9NZ01
NHMPKLRTFRLHSNN

SLIT2

196

O94813
HSSFRRHLPRQMQVS

SYT10

171

Q6XYQ8
QQGNPDRHFHQMIIR

ZNF582

131

Q96NG8
REALTNHRHQLVLAM

TTC28

291

Q96AY4
HMLQPDVNRRLHIDE

TSSK1B

251

Q9BXA7
MHQTHAIQRLEVLPS

nan

1

Q6ZS52
QFQRHMRDHERNDKP

ZNF236

51

Q9UL36
FRHHPQLSAMIRGQD

TSPYL6

256

Q8N831
SPLGHRMQLESRAHF

GTF3C2

871

Q8WUA4
TMEVLLQNHRLRDHN

ZNF423

896

Q2M1K9
MLQHFRQLNSPLHGL

LCMT2

231

O60294
GFRRPSEKNQHIMRH

ZNF711

741

Q9Y462
AMHEVFLQRLAAHPT

SNX32

136

Q86XE0
FNHMPKLRTFRLHSN

SLIT1

201

O75093
AMRAHQRLHSEQKPF

ZNF425

456

Q6IV72
LVRHQRAHLGEQPME

ZNF329

526

Q86UD4
VRLFHNTPGHRAMVE

TBL2

396

Q9Y4P3
DRHVNMHLNLRPFDC

ZBTB22

501

O15209
YRQRAHSNPMADHTL

METTL1

21

Q9UBP6
PAMHFVDHSLQVVRL

ZPBP2

261

Q6X784
NITVHRHLMLPDFDL

XRCC5

76

P13010
RNLPFVARQMALHAN

TSC2

1706

P49815
FRRPSEKNQHIMRHH

ZFY

781

P08048
RSFSRPSHLMRHQAI

ZNF473

466

Q8WTR7
NRLRVHAMTQHSVQP

ZFHX3

1236

Q15911
HLLEQHPRLIQRMES

USP54

646

Q70EL1
IPALIENDHHMNSIR

AGL

271

P35573
HMQRQRKLPEEHARF

PRKCZ

341

Q05513
LENLMDIHVFHRRRP

LRP4

986

O75096
LEQMERARHEPVNHS

MYO7A

926

Q13402