Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionSUMO ligase activity

RGPD4 RANBP2 RGPD8 KIAA1586 RGPD3

6.07e-07201715GO:0061665
GeneOntologyMolecularFunctionSUMO transferase activity

RGPD4 RANBP2 RGPD8 KIAA1586 RGPD3

1.32e-05361715GO:0019789
GeneOntologyMolecularFunctionATP-dependent activity

ACSL6 MYO5A SLC27A6 ATAD5 SMC6 KIF4A ABCA9 BPTF DNAH17 RAD54B MACF1 KIF4B KIF5B ATP12A DNAH5 HSPA14 DNAH11

2.20e-0561417117GO:0140657
GeneOntologyMolecularFunctionmicrotubule motor activity

KIF4A DNAH17 KIF4B KIF5B DNAH5 DNAH11

3.01e-05701716GO:0003777
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYO5A KIF4A DNAH17 KIF4B KIF5B DNAH5 DNAH11

7.09e-051181717GO:0003774
GeneOntologyMolecularFunctiondynein light intermediate chain binding

CCDC88A DNAH17 DNAH5 DNAH11

9.05e-05281714GO:0051959
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH17 DNAH5 DNAH11

4.58e-04181713GO:0008569
GeneOntologyMolecularFunctionsmall GTPase binding

RGPD4 RANBP2 RGPD8 MYO5A DOCK11 GCC2 RGPD3 RIMS4 RIMS2 XPO7

4.62e-0432117110GO:0031267
GeneOntologyMolecularFunctionstructural molecule activity

RPS4Y2 COL6A6 DSP KRT74 RPS4X RPS4Y1 MATR3 NUP88 EMILIN2 LAMA2 RPS25 CCDC6 NEB COL24A1 NUP133 MACF1 RIMS2 MUC5AC

6.52e-0489117118GO:0005198
GeneOntologyMolecularFunctionpeptidyl-prolyl cis-trans isomerase activity

RGPD4 RANBP2 RGPD8 RGPD3

8.80e-04501714GO:0003755
GeneOntologyMolecularFunctionextracellularly glycine-gated ion channel activity

GLRA2 GLRB

1.07e-0361712GO:0016933
GeneOntologyMolecularFunctionextracellularly glycine-gated chloride channel activity

GLRA2 GLRB

1.07e-0361712GO:0016934
GeneOntologyMolecularFunctioncis-trans isomerase activity

RGPD4 RANBP2 RGPD8 RGPD3

1.10e-03531714GO:0016859
GeneOntologyMolecularFunctionGTPase binding

RGPD4 RANBP2 RGPD8 MYO5A DOCK11 GCC2 RGPD3 RIMS4 RIMS2 XPO7

1.11e-0336017110GO:0051020
GeneOntologyBiologicalProcessRNA transport

RGPD4 RANBP2 RGPD8 NUP88 CKAP5 THOC5 NCBP2 SUPT6H RGPD3 NUP133 TNKS

1.92e-0717516711GO:0050658
GeneOntologyBiologicalProcessnucleic acid transport

RGPD4 RANBP2 RGPD8 NUP88 CKAP5 THOC5 NCBP2 SUPT6H RGPD3 NUP133 TNKS

1.92e-0717516711GO:0050657
GeneOntologyBiologicalProcessestablishment of RNA localization

RGPD4 RANBP2 RGPD8 NUP88 CKAP5 THOC5 NCBP2 SUPT6H RGPD3 NUP133 TNKS

2.28e-0717816711GO:0051236
GeneOntologyBiologicalProcessmRNA transport

RGPD4 RANBP2 RGPD8 NUP88 THOC5 NCBP2 SUPT6H RGPD3 NUP133 TNKS

2.98e-0714516710GO:0051028
GeneOntologyBiologicalProcessnuclear export

RGPD4 RANBP2 RGPD8 NUP88 THOC5 NCBP2 SUPT6H RGPD3 NUP133 IL1B XPO7

3.36e-0718516711GO:0051168
GeneOntologyBiologicalProcessNLS-bearing protein import into nucleus

RGPD4 RANBP2 RGPD8 RGPD3 RGPD5

4.60e-07201675GO:0006607
GeneOntologyBiologicalProcesspositive regulation of glucokinase activity

RGPD4 RANBP2 RGPD8 RGPD3

5.06e-0791674GO:0033133
GeneOntologyBiologicalProcesspositive regulation of hexokinase activity

RGPD4 RANBP2 RGPD8 RGPD3

8.38e-07101674GO:1903301
GeneOntologyBiologicalProcessregulation of isotype switching

SHLD2 ATAD5 RIF1 PTPRC SUPT6H PAXIP1

1.06e-06421676GO:0045191
GeneOntologyBiologicalProcessRNA localization

RGPD4 RANBP2 RGPD8 NUP88 CKAP5 THOC5 NCBP2 SUPT6H RGPD3 NUP133 TNKS

1.63e-0621716711GO:0006403
GeneOntologyBiologicalProcessregulation of glucokinase activity

RGPD4 RANBP2 RGPD8 RGPD3

2.80e-06131674GO:0033131
GeneOntologyBiologicalProcessregulation of hexokinase activity

RGPD4 RANBP2 RGPD8 RGPD3

3.90e-06141674GO:1903299
GeneOntologyBiologicalProcesspositive regulation of isotype switching

SHLD2 ATAD5 RIF1 PTPRC PAXIP1

4.70e-06311675GO:0045830
GeneOntologyBiologicalProcessnucleobase-containing compound transport

RGPD4 RANBP2 RGPD8 NUP88 CKAP5 THOC5 NCBP2 SUPT6H RGPD3 NUP133 TNKS

6.13e-0624916711GO:0015931
GeneOntologyBiologicalProcesssomatic recombination of immunoglobulin genes involved in immune response

SHLD2 ATAD5 RIF1 PTPRC SUPT6H PAXIP1

8.98e-06601676GO:0002204
GeneOntologyBiologicalProcesssomatic diversification of immunoglobulins involved in immune response

SHLD2 ATAD5 RIF1 PTPRC SUPT6H PAXIP1

8.98e-06601676GO:0002208
GeneOntologyBiologicalProcessisotype switching

SHLD2 ATAD5 RIF1 PTPRC SUPT6H PAXIP1

8.98e-06601676GO:0045190
GeneOntologyBiologicalProcessB cell activation involved in immune response

SHLD2 DOCK11 ATAD5 RIF1 PTPRC SUPT6H PAXIP1

1.83e-051011677GO:0002312
GeneOntologyBiologicalProcesssomatic recombination of immunoglobulin gene segments

SHLD2 ATAD5 RIF1 PTPRC SUPT6H PAXIP1

2.02e-05691676GO:0016447
GeneOntologyBiologicalProcessregulation of DNA recombination

SHLD2 ATAD5 TEX15 TRRAP RIF1 PTPRC SUPT6H PAXIP1

3.10e-051501678GO:0000018
GeneOntologyBiologicalProcessimmunoglobulin production involved in immunoglobulin-mediated immune response

SHLD2 ATAD5 RIF1 PTPRC SUPT6H PAXIP1

3.27e-05751676GO:0002381
GeneOntologyBiologicalProcesssomatic diversification of immunoglobulins

SHLD2 ATAD5 RIF1 PTPRC SUPT6H PAXIP1

3.80e-05771676GO:0016445
GeneOntologyBiologicalProcesslymphocyte activation involved in immune response

SHLD2 RC3H2 DOCK11 ATAD5 RELB RIF1 PTPRC SUPT6H PAXIP1 EIF2AK4

3.96e-0525116710GO:0002285
GeneOntologyBiologicalProcessregulation of adaptive immune response

SHLD2 RC3H2 ATAD5 ARG1 RIF1 PTPRC SUPT6H PAXIP1 EIF2AK4 IL1B

4.09e-0525216710GO:0002819
GeneOntologyBiologicalProcessregulation of immunoglobulin mediated immune response

SHLD2 ATAD5 RIF1 PTPRC SUPT6H PAXIP1

4.39e-05791676GO:0002889
GeneOntologyBiologicalProcessregulation of B cell mediated immunity

SHLD2 ATAD5 RIF1 PTPRC SUPT6H PAXIP1

4.39e-05791676GO:0002712
GeneOntologyBiologicalProcesspositive regulation of DNA recombination

SHLD2 ATAD5 TRRAP RIF1 PTPRC PAXIP1

4.72e-05801676GO:0045911
GeneOntologyBiologicalProcesssomatic cell DNA recombination

SHLD2 ATAD5 RIF1 PTPRC SUPT6H PAXIP1

5.42e-05821676GO:0016444
GeneOntologyBiologicalProcesssomatic diversification of immune receptors via germline recombination within a single locus

SHLD2 ATAD5 RIF1 PTPRC SUPT6H PAXIP1

5.42e-05821676GO:0002562
GeneOntologyBiologicalProcessnuclear transport

RGPD4 RANBP2 RGPD8 NUP88 THOC5 NCBP2 SUPT6H RGPD3 NUP133 IL1B RGPD5 XPO7

6.19e-0537816712GO:0051169
GeneOntologyBiologicalProcessnucleocytoplasmic transport

RGPD4 RANBP2 RGPD8 NUP88 THOC5 NCBP2 SUPT6H RGPD3 NUP133 IL1B RGPD5 XPO7

6.19e-0537816712GO:0006913
GeneOntologyBiologicalProcesspositive regulation of immunoglobulin mediated immune response

SHLD2 ATAD5 RIF1 PTPRC PAXIP1

8.97e-05561675GO:0002891
GeneOntologyBiologicalProcesspositive regulation of B cell mediated immunity

SHLD2 ATAD5 RIF1 PTPRC PAXIP1

8.97e-05561675GO:0002714
GeneOntologyBiologicalProcesssomatic diversification of immune receptors

SHLD2 ATAD5 RIF1 PTPRC SUPT6H PAXIP1

9.72e-05911676GO:0002200
GeneOntologyBiologicalProcessregulation of immunoglobulin production

SHLD2 ATAD5 RIF1 PTPRC SUPT6H PAXIP1

1.23e-04951676GO:0002637
GeneOntologyBiologicalProcessregulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains

SHLD2 RC3H2 ATAD5 ARG1 RIF1 PTPRC SUPT6H PAXIP1 IL1B

1.31e-042351679GO:0002822
GeneOntologyBiologicalProcesspositive regulation of immunoglobulin production

SHLD2 ATAD5 RIF1 PTPRC PAXIP1

1.35e-04611675GO:0002639
GeneOntologyBiologicalProcesspositive regulation of isotype switching to IgG isotypes

ATAD5 PTPRC PAXIP1

1.40e-04131673GO:0048304
GeneOntologyBiologicalProcessregulation of immune response

UBR2 SHLD2 RC3H2 THEMIS ATAD5 MATR3 TRGC1 TRGC2 IRAK2 STAT2 ARG1 RIF1 PTPRC SUPT6H PHF11 PAXIP1 EIF2AK4 IL1B SMCR8 LRRFIP2 VSTM1

1.89e-04108516721GO:0050776
GeneOntologyBiologicalProcessDNA recombination

UBR2 SHLD2 ATAD5 SMC6 TEX15 TRRAP RIF1 PTPRC SUPT6H RAD54B PAXIP1

2.12e-0436816711GO:0006310
GeneOntologyBiologicalProcessprotein peptidyl-prolyl isomerization

RGPD4 RANBP2 RGPD8 RGPD3

2.47e-04381674GO:0000413
GeneOntologyBiologicalProcesspositive regulation of adaptive immune response

SHLD2 ATAD5 RIF1 PTPRC PAXIP1 EIF2AK4 IL1B

3.20e-041591677GO:0002821
GeneOntologyBiologicalProcessregulation of isotype switching to IgG isotypes

ATAD5 PTPRC PAXIP1

3.26e-04171673GO:0048302
GeneOntologyBiologicalProcessregulation of RNA export from nucleus

THOC5 NCBP2 SUPT6H

3.26e-04171673GO:0046831
GeneOntologyBiologicalProcessmRNA export from nucleus

NUP88 THOC5 NCBP2 SUPT6H NUP133

3.36e-04741675GO:0006406
GeneOntologyBiologicalProcessintracellular protein transport

RGPD4 RANBP2 PSAP RGPD8 MYO5A NUP88 PXK GCC2 RGPD3 NUP133 KIF5B EDEM1 IL1B RIMS2 RGPD5 XPO7

3.48e-0474016716GO:0006886
GeneOntologyBiologicalProcessisotype switching to IgG isotypes

ATAD5 PTPRC PAXIP1

3.89e-04181673GO:0048291
GeneOntologyBiologicalProcessintracellular transport

RGPD4 RANBP2 PSAP RGPD8 MYO5A NUP88 KIF4A PXK THOC5 NCBP2 CCDC88A LMX1B SUPT6H GCC2 RGPD3 NUP133 FMN2 KIF5B TACC3 EDEM1 IL1B RIMS2 TRAPPC9 RGPD5 XPO7

4.29e-04149616725GO:0046907
GeneOntologyBiologicalProcesscytoplasmic translation

RPS4Y2 RPS4X RPS4Y1 CKAP5 RPS25 NCBP2 EIF2AK4

5.14e-041721677GO:0002181
GeneOntologyBiologicalProcessregulation of nucleobase-containing compound transport

THOC5 NCBP2 SUPT6H

5.37e-04201673GO:0032239
GeneOntologyBiologicalProcesspositive regulation of leukocyte mediated immunity

SHLD2 ATAD5 ARG1 RIF1 PTPRC PAXIP1 IL1B

5.69e-041751677GO:0002705
GeneOntologyBiologicalProcessregulation of production of molecular mediator of immune response

SHLD2 ATAD5 ARG1 RIF1 PTPRC SUPT6H PAXIP1 IL1B

6.04e-042311678GO:0002700
GeneOntologyBiologicalProcessregulation of lymphocyte mediated immunity

SHLD2 ATAD5 ARG1 RIF1 PTPRC SUPT6H PAXIP1 IL1B

6.21e-042321678GO:0002706
GeneOntologyBiologicalProcessleukocyte activation involved in immune response

SHLD2 RC3H2 DOCK11 ATAD5 RELB RIF1 PTPRC SUPT6H PAXIP1 EIF2AK4

7.42e-0436116710GO:0002366
GeneOntologyBiologicalProcesscell activation involved in immune response

SHLD2 RC3H2 DOCK11 ATAD5 RELB RIF1 PTPRC SUPT6H PAXIP1 EIF2AK4

8.07e-0436516710GO:0002263
GeneOntologyCellularComponentnuclear pore

RGPD4 RANBP2 RGPD8 NUP88 RGPD3 NUP133 TNKS RGPD5 XPO7

1.25e-071011689GO:0005643
GeneOntologyCellularComponentcytoplasmic periphery of the nuclear pore complex

RGPD4 RANBP2 RGPD8 RGPD3

2.75e-0781684GO:1990723
GeneOntologyCellularComponentSUMO ligase complex

RGPD4 RANBP2 RGPD8 SMC6 RGPD3

5.79e-07211685GO:0106068
GeneOntologyCellularComponentnuclear pore cytoplasmic filaments

RGPD4 RANBP2 RGPD8 RGPD3

8.14e-07101684GO:0044614
GeneOntologyCellularComponentannulate lamellae

RGPD4 RANBP2 RGPD8 RGPD3

3.78e-06141684GO:0005642
GeneOntologyCellularComponentinclusion body

RGPD4 RANBP2 PSAP RGPD8 RGPD3 EDEM1 CABIN1

8.15e-06901687GO:0016234
GeneOntologyCellularComponentnuclear pore nuclear basket

RGPD4 RANBP2 RGPD8 RGPD3

1.13e-05181684GO:0044615
GeneOntologyCellularComponentnuclear inclusion body

RGPD4 RANBP2 RGPD8 RGPD3

1.76e-05201684GO:0042405
GeneOntologyCellularComponentcentrosome

DISC1 CNTRL RTTN CCDC18 CKAP5 IST1 RELB CCDC77 PXK CCDC88A FBXL7 AK5 IQCB1 CEP83 TNKS KIF5B TACC3

1.62e-0477016817GO:0005813
GeneOntologyCellularComponentcytoplasmic region

EFCAB6 CNTRL CKAP5 KIF4A AKAP14 DNAH17 RIMS4 KIF5B RIMS2 DNAH5 DNAH11

1.65e-0436016811GO:0099568
GeneOntologyCellularComponentnuclear envelope

RGPD4 ZNF383 RANBP2 RGPD8 MATR3 NUP88 IST1 RIF1 RGPD3 PHF11 NUP133 TNKS RGPD5 XPO7

1.79e-0456016814GO:0005635
GeneOntologyCellularComponentmicrotubule associated complex

DISC1 KIF4A DNAH17 KIF4B KIF5B DNAH5 DNAH11

3.30e-041611687GO:0005875
GeneOntologyCellularComponentsmall-subunit processome

RPS4Y2 RPS4X RPS4Y1 PDCD11 UTP20

3.68e-04761685GO:0032040
GeneOntologyCellularComponentcytosolic small ribosomal subunit

RPS4Y2 RPS4X RPS4Y1 RPS25

5.05e-04461684GO:0022627
GeneOntologyCellularComponentnuclear membrane

RGPD4 ZNF383 RANBP2 RGPD8 MATR3 RIF1 RGPD3 PHF11 NUP133 TNKS

5.41e-0434916810GO:0031965
GeneOntologyCellularComponentcentriolar satellite

CNTRL CCDC18 PXK AK5 KIF5B TACC3

5.96e-041281686GO:0034451
GeneOntologyCellularComponentnuclear protein-containing complex

RGPD4 SIN3B RANBP2 THEMIS RGPD8 HLF NUP88 HIPK2 RELB XPA SYF2 TRRAP THOC5 STAT2 PHC1 BPTF SUPT6H RGPD3 PAXIP1 NUP133 TNKS RGPD5 XPO7

6.78e-04137716823GO:0140513
GeneOntologyCellularComponentpostsynaptic specialization

DISC1 RPS25 CLSTN1 USP6 GLRA2 GLRB SCN8A LRP4 MACF1 PLCB4 TACC3 KCNT1

7.86e-0450316812GO:0099572
GeneOntologyCellularComponentdynein complex

DISC1 DNAH17 DNAH5 DNAH11

9.31e-04541684GO:0030286
GeneOntologyCellularComponent9+0 motile cilium

DNAH5 DNAH11

9.43e-0461682GO:0097728
GeneOntologyCellularComponentgamma-delta T cell receptor complex

TRGC1 TRGC2

9.43e-0461682GO:0042106
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

EFCAB6 CNTRL CKAP5 KIF4A AKAP14 DNAH17 KIF5B DNAH5 DNAH11

1.09e-033171689GO:0032838
GeneOntologyCellularComponentmicrotubule organizing center

DISC1 CNTRL RTTN CCDC18 CKAP5 IST1 RELB CCDC77 PXK CCDC88A FBXL7 AK5 IQCB1 CEP83 TNKS KIF5B TACC3

1.20e-0391916817GO:0005815
GeneOntologyCellularComponentcytoskeleton of presynaptic active zone

RIMS4 RIMS2

1.74e-0381682GO:0048788
GeneOntologyCellularComponentpreribosome

RPS4Y2 RPS4X RPS4Y1 PDCD11 UTP20

2.29e-031141685GO:0030684
MousePhenoelevated level of mitotic sister chromatid exchange

RGPD4 RANBP2 RGPD8 PARP2 RGPD3

3.88e-07161415MP:0003701
MousePhenoabnormal cell cycle

RGPD4 UBR2 SIN3B RANBP2 CYP26B1 RGPD8 PARP2 HIPK2 TEX15 SYF2 CCDC6 RIF1 RGPD3 PAXIP1 FMN2 TACC3 ZMYM3

1.91e-0552014117MP:0003077
MousePhenoabnormal tumor latency

RGPD4 RANBP2 RGPD8 RGPD3 TREM1

2.14e-05341415MP:0010307
MousePhenosmall cerebellum

PSAP DISC1 MATR3 LMX1A LMX1B SCN8A PLCB4 DNAH5

2.68e-051191418MP:0000852
MousePhenoabnormal contextual conditioning behavior

UBL7 EPHA6 DISC1 MATR3 KIF4A LHX8 CCDC88A KIF4B EIF2AK4 KCNT1

4.30e-0520514110MP:0001469
MousePhenoabnormal mitosis

RGPD4 RANBP2 RGPD8 PARP2 RIF1 RGPD3 PAXIP1 TACC3

4.54e-051281418MP:0004046
MousePhenoabnormal epididymis morphology

RGPD4 DPYD RANBP2 GGNBP2 PSAP RGPD8 EPHA6 XPA RGPD3 FHL5 ZMYM3

8.82e-0526914111MP:0002631
MousePhenolethality at weaning, complete penetrance

PSAP MYO5A RELB NEB DNAH5

9.56e-05461415MP:0011083
MousePhenobiventricular, ambiguous atrioventricular connection

DNAH5 DNAH11

1.01e-0421412MP:0011511
MousePhenoabnormal morula morphology

RGPD4 RANBP2 RGPD8 RGPD3

1.25e-04261414MP:0012058
MousePhenoincreased lung carcinoma incidence

RGPD4 RANBP2 RGPD8 ATAD5 XPA RGPD3

1.34e-04781416MP:0008714
MousePhenoabnormal temporal memory

UBL7 EPHA6 DISC1 MATR3 KIF4A LHX8 CCDC88A KIF4B EIF2AK4 KCNT1

1.54e-0423914110MP:0001468
MousePhenolethality at weaning

PSAP MYO5A RELB NEB PTPRC DNAH5

2.02e-04841416MP:0008569
MousePhenodecreased tumor latency

RGPD4 RANBP2 RGPD8 RGPD3

2.22e-04301414MP:0010308
MousePhenofailure of blastocyst formation

RGPD4 RANBP2 RGPD8 RGPD3

2.53e-04311414MP:0012129
MousePhenoabnormal epididymis size

RGPD4 RANBP2 GGNBP2 PSAP RGPD8 EPHA6 RGPD3 ZMYM3

2.77e-041661418MP:0004926
MousePhenobiventricular, discordant atrioventricular connection

DNAH5 DNAH11

3.01e-0431412MP:0011510
MousePhenoincreased dendritic spine number

KIF4A KIF4B

3.01e-0431412MP:0021019
MousePhenoabnormal DNA repair

ATAD5 PARP2 XPA TEX15 LHX8 RIF1 PAXIP1

3.44e-041301417MP:0008058
MousePhenoprogressive muscle weakness

PSAP LAMA2 NEB SCN8A

3.64e-04341414MP:0000748
MousePhenoaneuploidy

RGPD4 RANBP2 RGPD8 ATAD5 RGPD3

3.68e-04611415MP:0004024
DomainTPR-contain_dom

RGPD4 RANBP2 NAA15 RGPD8 TTC3 IFIT3 TTC7B RGPD3 PDCD11 TTC9 CABIN1 RGPD5

1.04e-0815016712IPR013026
DomainGrip

RGPD4 RGPD8 GCC2 RGPD3 RGPD5

2.38e-08111675SM00755
DomainGRIP

RGPD4 RGPD8 GCC2 RGPD3 RGPD5

2.38e-08111675PF01465
DomainRan_BP1

RGPD4 RANBP2 RGPD8 RGPD3 RGPD5

4.05e-08121675PF00638
DomainRANBD1

RGPD4 RANBP2 RGPD8 RGPD3 RGPD5

4.05e-08121675PS50196
DomainGRIP_dom

RGPD4 RGPD8 GCC2 RGPD3 RGPD5

4.05e-08121675IPR000237
DomainGRIP

RGPD4 RGPD8 GCC2 RGPD3 RGPD5

4.05e-08121675PS50913
DomainRanBD

RGPD4 RANBP2 RGPD8 RGPD3 RGPD5

6.54e-08131675SM00160
DomainRan_bind_dom

RGPD4 RANBP2 RGPD8 RGPD3 RGPD5

6.54e-08131675IPR000156
DomainTPR-like_helical_dom

RGPD4 RANBP2 NAA15 RGPD8 TTC3 TRRAP IFIT3 TTC7B RGPD3 PDCD11 TTC9 CABIN1 RGPD5

1.82e-0723316713IPR011990
DomainRab_bind

RGPD4 RGPD8 GCC2 RGPD3

2.11e-0771674PF16704
DomainGCC2_Rab_bind

RGPD4 RGPD8 GCC2 RGPD3

2.11e-0771674IPR032023
DomainTPR

RGPD4 RANBP2 NAA15 RGPD8 TTC3 IFIT3 TTC7B RGPD3 TTC9 CABIN1

2.46e-0712916710SM00028
DomainTPR_REGION

RGPD4 RANBP2 NAA15 RGPD8 TTC3 IFIT3 TTC7B RGPD3 TTC9 CABIN1 RGPD5

2.82e-0716516711PS50293
DomainTPR

RGPD4 RANBP2 NAA15 RGPD8 TTC3 IFIT3 TTC7B RGPD3 TTC9 CABIN1 RGPD5

2.82e-0716516711PS50005
DomainTPR_repeat

RGPD4 RANBP2 NAA15 RGPD8 TTC3 IFIT3 TTC7B RGPD3 TTC9 CABIN1

3.27e-0713316710IPR019734
Domain-

RGPD4 RANBP2 NAA15 RGPD8 TTC3 TRRAP IFIT3 TTC7B RGPD3 PDCD11 TTC9 CABIN1

3.64e-07207167121.25.40.10
DomainRIBOSOMAL_S4E

RPS4Y2 RPS4X RPS4Y1

7.02e-0731673PS00528
DomainRibosomal_S4e_central_region

RPS4Y2 RPS4X RPS4Y1

7.02e-0731673IPR013845
DomainRibosomal_S4e_N

RPS4Y2 RPS4X RPS4Y1

7.02e-0731673IPR013843
DomainRibosomal_S4e_central

RPS4Y2 RPS4X RPS4Y1

7.02e-0731673PD002667
Domain40S_S4_C

RPS4Y2 RPS4X RPS4Y1

7.02e-0731673PF16121
Domain40S_S4_C

RPS4Y2 RPS4X RPS4Y1

7.02e-0731673IPR032277
DomainRibosomal_S4e_N_CS

RPS4Y2 RPS4X RPS4Y1

7.02e-0731673IPR018199
DomainRS4NT

RPS4Y2 RPS4X RPS4Y1

7.02e-0731673PF08071
DomainRibosomal_S4e

RPS4Y2 RPS4X RPS4Y1

7.02e-0731673IPR000876
DomainRibosomal_S4e

RPS4Y2 RPS4X RPS4Y1

7.02e-0731673PF00900
Domain-

RGPD4 RGPD8 GCC2 RGPD3

1.24e-061016741.10.220.60
DomainTPR_1

RANBP2 NAA15 RGPD8 TTC3 IFIT3 TTC7B TTC9 RGPD5

1.44e-06901678IPR001440
DomainTPR_1

RANBP2 NAA15 RGPD8 TTC3 IFIT3 TTC7B TTC9 RGPD5

1.44e-06901678PF00515
DomainS4

RPS4Y2 RPS4X RPS4Y1

6.93e-0651673SM00363
DomainS4

RPS4Y2 RPS4X RPS4Y1

6.93e-0651673PS50889
DomainS4_RNA-bd

RPS4Y2 RPS4X RPS4Y1

1.38e-0561673IPR002942
DomainTPR_2

NAA15 TTC3 IFIT3 TTC7B TTC9

8.24e-05501675PF07719
DomainTPR_2

NAA15 TTC3 IFIT3 TTC7B TTC9

8.24e-05501675IPR013105
DomainKOW

RPS4Y2 RPS4X RPS4Y1

1.10e-04111673IPR005824
DomainKOW

RPS4Y2 RPS4X RPS4Y1

1.10e-04111673PF00467
DomainLIM

LHX8 LMX1A LMX1B ABLIM2 FHL5

3.81e-04691675PF00412
Domain-

LHX8 LMX1A LMX1B ABLIM2 FHL5

4.08e-047016752.10.110.10
DomainLIM

LHX8 LMX1A LMX1B ABLIM2 FHL5

4.35e-04711675SM00132
DomainZnf_LIM

LHX8 LMX1A LMX1B ABLIM2 FHL5

4.35e-04711675IPR001781
DomainLIM_DOMAIN_1

LHX8 LMX1A LMX1B ABLIM2 FHL5

4.35e-04711675PS00478
DomainLIM_DOMAIN_2

LHX8 LMX1A LMX1B ABLIM2 FHL5

4.35e-04711675PS50023
DomainPrefoldin

DSP DISC1 TRAIP KIF4A TXLNA

4.64e-04721675IPR009053
DomainS4

RPS4X RPS4Y1

4.71e-0441672PF01479
Domain-

DSP MACF1

1.16e-03616723.90.1290.10
DomainWGR_domain

PARP2 LAMA2 TNKS

1.24e-03241673IPR008893
DomainPlectin

DSP MACF1

1.62e-0371672PF00681
DomainZnf_MYM

PHC1 ZMYM3

1.62e-0371672IPR010507
DomainPlectin_repeat

DSP MACF1

1.62e-0371672IPR001101
Domainzf-FCS

PHC1 ZMYM3

1.62e-0371672PF06467
DomainPLEC

DSP MACF1

1.62e-0371672SM00250
DomainDHC_N1

DNAH5 DNAH11

2.15e-0381672PF08385
DomainS1

SUPT6H PDCD11

2.15e-0381672PF00575
DomainDynein_heavy_dom-1

DNAH5 DNAH11

2.15e-0381672IPR013594
DomainSpectrin_repeat

DSP MCF2 MACF1

2.16e-03291673IPR002017
DomainSPEC

DSP MCF2 MACF1

2.88e-03321673SM00150
DomainSpectrin/alpha-actinin

DSP MCF2 MACF1

2.88e-03321673IPR018159
DomainS1

SUPT6H PDCD11

3.41e-03101672PS50126
DomainCyt_P450_E_grp-IV

CYP26B1 CYP51A1

3.41e-03101672IPR002403
DomainS1

SUPT6H PDCD11

4.95e-03121672SM00316
DomainS1_dom

SUPT6H PDCD11

4.95e-03121672IPR022967
DomainS1_domain

SUPT6H PDCD11

4.95e-03121672IPR003029
DomainC8

FCGBP MUC5AC

4.95e-03121672PF08742
DomainTIL

FCGBP MUC5AC

4.95e-03121672PF01826
DomainPH_dom-like

RGPD4 RANBP2 RGPD8 DOCK11 TBC1D2 MCF2 RGPD3 OSBPL1A PLCB4 RGPD5

5.08e-0342616710IPR011993
DomainUnchr_dom_Cys-rich

FCGBP MUC5AC

5.81e-03131672IPR014853
DomainC8

FCGBP MUC5AC

5.81e-03131672SM00832
DomainKinesin_motor_CS

KIF4A KIF4B KIF5B

5.83e-03411673IPR019821
DomainKinesin-like_fam

KIF4A KIF4B KIF5B

6.67e-03431673IPR027640
DomainDynein_heavy_chain_D4_dom

DNAH5 DNAH11

6.74e-03141672IPR024317
DomainDynein_HC_stalk

DNAH5 DNAH11

6.74e-03141672IPR024743
DomainDynein_heavy_dom-2

DNAH5 DNAH11

6.74e-03141672IPR013602
DomainDHC_N2

DNAH5 DNAH11

6.74e-03141672PF08393
DomainTIL_dom

FCGBP MUC5AC

6.74e-03141672IPR002919
DomainATPase_dyneun-rel_AAA

DNAH5 DNAH11

6.74e-03141672IPR011704
DomainMT

DNAH5 DNAH11

6.74e-03141672PF12777
DomainAAA_8

DNAH5 DNAH11

6.74e-03141672PF12780
DomainAAA_5

DNAH5 DNAH11

6.74e-03141672PF07728
Domain-

KIF4A KIF4B KIF5B

7.11e-034416733.40.850.10
DomainKinesin

KIF4A KIF4B KIF5B

7.11e-03441673PF00225
DomainKISc

KIF4A KIF4B KIF5B

7.11e-03441673SM00129
DomainKINESIN_MOTOR_1

KIF4A KIF4B KIF5B

7.11e-03441673PS00411
DomainKinesin_motor_dom

KIF4A KIF4B KIF5B

7.11e-03441673IPR001752
DomainKINESIN_MOTOR_2

KIF4A KIF4B KIF5B

7.11e-03441673PS50067
DomainDHC_fam

DNAH5 DNAH11

7.73e-03151672IPR026983
DomainDynein_heavy

DNAH5 DNAH11

7.73e-03151672PF03028
DomainDynein_heavy_dom

DNAH5 DNAH11

7.73e-03151672IPR004273
Domain-

RGPD4 RANBP2 RGPD8 DOCK11 TBC1D2 MCF2 RGPD3 OSBPL1A PLCB4

8.71e-0339116792.30.29.30
DomainVWF_type-D

FCGBP MUC5AC

8.78e-03161672IPR001846
DomainVWFD

FCGBP MUC5AC

8.78e-03161672PS51233
DomainVWD

FCGBP MUC5AC

8.78e-03161672SM00216
DomainVWD

FCGBP MUC5AC

8.78e-03161672PF00094
PathwayREACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA

RGPD4 RANBP2 RGPD8 NUP88 NCBP2 RGPD3 NUP133

1.61e-07431367MM14609
PathwayREACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS

RGPD4 RANBP2 RGPD8 NUP88 NCBP2 RGPD3 NUP133

4.71e-07501367MM14610
PathwayREACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS

RGPD4 RANBP2 RGPD8 NUP88 PHC1 RGPD3 NUP133

1.33e-06581367MM15149
PathwayREACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS

RGPD4 RANBP2 RGPD8 SMC6 NUP88 PHC1 RGPD3 NUP133

1.44e-06841368MM14929
PathwayREACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY

RGPD4 RANBP2 RGPD8 NUP88 RGPD3 NUP133

2.12e-06401366MM14945
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS

RGPD4 RANBP2 RGPD8 NUP88 RGPD3 NUP133

2.46e-06411366MM15200
PathwayREACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS

RGPD4 RANBP2 RGPD8 NUP88 RGPD3 NUP133

2.85e-06421366MM15039
PathwayREACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS

RGPD4 RANBP2 RGPD8 NUP88 PHC1 RGPD3 NUP133

2.91e-06651367MM15147
PathwayREACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS

RGPD4 RANBP2 RGPD8 NUP88 RGPD3 NUP133

5.60e-06471366MM14939
PathwayREACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE

RGPD4 RANBP2 RGPD8 NUP88 RGPD3 NUP133 HSPA14

6.39e-06731367MM14948
PathwayREACTOME_GENE_SILENCING_BY_RNA

RGPD4 RANBP2 RGPD8 NUP88 RGPD3 NUP133

7.18e-06491366MM14837
PathwayREACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS

RGPD4 RANBP2 RGPD8 NUP88 RGPD3 NUP133

9.10e-06511366MM15151
PathwayREACTOME_NUCLEAR_ENVELOPE_BREAKDOWN

RGPD4 RANBP2 RGPD8 NUP88 RGPD3 NUP133

1.42e-05551366MM14917
PathwayREACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM

RGPD4 RANBP2 RGPD8 NUP88 NCBP2 RGPD3 NUP133

1.90e-05861367MM15413
PathwayREACTOME_SNRNP_ASSEMBLY

RGPD4 RANBP2 RGPD8 NUP88 RGPD3 NUP133

1.94e-05581366MM14736
PathwayBIOCARTA_RANBP2_PATHWAY

RGPD4 RANBP2 RGPD8 RGPD3

2.28e-05181364MM1549
PathwayREACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS

RGPD4 RANBP2 RGPD8 NUP88 RGPD3 NUP133 HSPA14

2.95e-05921367MM14951
PathwayREACTOME_SUMOYLATION

RGPD4 RANBP2 RGPD8 SMC6 NUP88 HIPK2 PHC1 RGPD3 NUP133

3.76e-051691369MM14919
PathwayREACTOME_GLUCOSE_METABOLISM

RGPD4 RANBP2 RGPD8 NUP88 RGPD3 NUP133

1.39e-04821366MM15394
PathwayREACTOME_SARS_COV_2_HOST_INTERACTIONS

RPS4Y2 RANBP2 RPS4X RPS4Y1 NUP88 IRAK2 RPS25 STAT2 NUP133

1.60e-042041369M45011
PathwayREACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA

RANBP2 NUP88 NCBP2 NUP133

3.84e-04361364M26974
PathwayREACTOME_AMPLIFICATION_OF_SIGNAL_FROM_THE_KINETOCHORES

RGPD4 RANBP2 RGPD8 CKAP5 RGPD3 NUP133

4.10e-041001366MM14561
PathwayREACTOME_SARS_COV_1_MODULATES_HOST_TRANSLATION_MACHINERY

RPS4Y2 RPS4X RPS4Y1 RPS25

4.28e-04371364M46427
PathwayREACTOME_NERVOUS_SYSTEM_DEVELOPMENT

RPS4Y2 CACNB2 EPHA6 COL6A6 RPS4X RPS4Y1 CYP51A1 LAMA2 KIF4A RPS25 NCBP2 PTPRC SCN8A KIF4B ABLIM2

4.34e-0457513615M29853
PathwayREACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS

RANBP2 NUP88 NCBP2 NUP133

7.64e-04431364M26975
PathwayREACTOME_INFLUENZA_INFECTION

RPS4Y2 RANBP2 RPS4X RPS4Y1 NUP88 RPS25 NUP133

8.17e-041571367M4669
PathwayREACTOME_MITOTIC_PROPHASE

RGPD4 RANBP2 RGPD8 NUP88 RGPD3 NUP133

8.21e-041141366MM15361
PathwayREACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS

RANBP2 SMC6 NUP88 PHC1 NUP133

8.79e-04771365M27226
PathwayREACTOME_MITOTIC_SPINDLE_CHECKPOINT

RGPD4 RANBP2 RGPD8 CKAP5 RGPD3 NUP133

9.40e-041171366MM15387
PathwayREACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS

RANBP2 NUP88 PHC1 NUP133

1.07e-03471364M27395
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

SIN3B RANBP2 DSP ATAD5 RPS4X MATR3 PARP2 NUP88 CKAP5 KIF4A RPS25 SYF2 CMAS TRRAP NKRF THOC5 NCBP2 BPTF RIF1 SUPT6H RGPD3 PAXIP1 NUP133 PDCD11 ING4 UTP20 CABIN1 TASOR ZMYM3

9.79e-1212941722930804502
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

RANBP2 NAA15 MYO5A DSP USP11 RPS4X NUP88 CKAP5 KIF4A TRRAP NKRF BPTF RIF1 SUPT6H NUP133 PDCD11 MACF1 UTP20 KIF5B ZMYM3 XPO7

1.40e-116531722122586326
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

MYO5A ATAD5 TRAIP MATR3 SMC6 CKAP5 KIF4A RPS25 CMAS TRRAP NKRF BPTF RIF1 TXLNA IQCB1 NUP133 PDCD11 MACF1 UTP20 TASOR HSPA14 LRRFIP2

3.27e-117591722235915203
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

UBR2 SIN3B RANBP2 DSP USP11 PARP2 CKAP5 KIF4A RELB TRRAP NKRF BPTF RIF1 PRDM10 NUP133 UTP20 KIF5B CABIN1 HSPA14 ZMYM3 LRRFIP2 XPO7

3.24e-108571722225609649
Pubmed

Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function.

RGPD4 RANBP2 RGPD8 RGPD3 KIF5B

3.46e-109172517887960
Pubmed

The docking of kinesins, KIF5B and KIF5C, to Ran-binding protein 2 (RanBP2) is mediated via a novel RanBP2 domain.

RGPD4 RANBP2 RGPD8 RGPD3 KIF5B

3.46e-109172511553612
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

RGPD4 SIN3B CACNB2 RANBP2 RGPD8 MYO5A DOCK11 MATR3 CKAP5 KIF4A CCDC6 TTC3 TXLNA CCDC88A RGPD3 MACF1 KIF4B TNKS KIF5B TACC3 CABIN1 KCNT1 LRRFIP2

5.02e-109631722328671696
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

RGPD4 RPS4Y2 RANBP2 GGNBP2 RGPD8 MYO5A DSP KRT74 RPS4X RPS4Y1 MATR3 CNTRL RPS25 CCDC77 NEB TTC3 BPTF GCLC RGPD3 CEP83 MACF1 EIF2AK4 KIF5B PPIP5K2 ATP12A RIMS2 TASOR RGPD5

6.08e-1014421722835575683
Pubmed

Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons.

RGPD4 RANBP2 RGPD8 NUP88 RGPD3

3.48e-0913172531427429
Pubmed

Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2.

RGPD4 RANBP2 RGPD8 RGPD3

2.00e-08717249037092
Pubmed

Complex genomic rearrangements lead to novel primate gene function.

RGPD4 RGPD8 RGPD3 RGPD5

2.00e-087172415710750
Pubmed

Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene.

RGPD4 RANBP2 RGPD8 RGPD3

2.00e-087172411353387
Pubmed

Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons.

RGPD4 RANBP2 RGPD8 RGPD3

2.00e-087172430944974
Pubmed

Nucleoporin Nup358 drives the differentiation of myeloid-biased multipotent progenitors by modulating HDAC3 nuclear translocation.

RGPD4 RANBP2 RGPD8 RGPD3

2.00e-087172438838144
Pubmed

Retina-specifically expressed novel subtypes of bovine cyclophilin.

RGPD4 RANBP2 RGPD8 RGPD3

2.00e-08717247559465
Pubmed

Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate.

RGPD4 RANBP2 RGPD8 RGPD3

2.00e-087172417372272
Pubmed

Proteostatic Remodeling of Small Heat Shock Chaperones─Crystallins by Ran-Binding Protein 2─and the Peptidyl-Prolyl cis-trans Isomerase and Chaperone Activities of Its Cyclophilin Domain.

RGPD4 RANBP2 RGPD8 RGPD3

2.00e-087172438657106
Pubmed

Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis.

RGPD4 RANBP2 RGPD8 RGPD3

2.00e-087172421205196
Pubmed

Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons.

RGPD4 RANBP2 RGPD8 RGPD3

2.00e-087172418949001
Pubmed

Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.

RGPD4 RANBP2 RGPD8 RGPD3

2.00e-087172425187515
Pubmed

Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex.

RGPD4 RANBP2 RGPD8 RGPD3

2.00e-08717248603673
Pubmed

Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2).

RGPD4 RANBP2 RGPD8 RGPD3

2.00e-087172426632511
Pubmed

Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.

RGPD4 RANBP2 RGPD8 RGPD3

2.00e-087172424403063
Pubmed

Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.

RGPD4 RANBP2 RGPD8 RGPD3

2.00e-087172423818861
Pubmed

Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2.

RGPD4 RANBP2 RGPD8 RGPD3

2.00e-087172423536549
Pubmed

Identification of RanBP2- and kinesin-mediated transport pathways with restricted neuronal and subcellular localization.

RGPD4 RANBP2 RGPD8 RGPD3

2.00e-087172412191015
Pubmed

Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

RGPD4 RANBP2 RGPD8 RGPD3

2.00e-087172422821000
Pubmed

Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress.

RGPD4 RANBP2 RGPD8 RGPD3

2.00e-087172420682751
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

RGPD4 SIN3B RANBP2 RGPD8 DSP NUP88 CKAP5 PHC1 CCDC88A GCC2 RGPD3 TACC3 TASOR ZMYM3

2.50e-084181721434709266
Pubmed

Peering through the pore: nuclear pore complex structure, assembly, and function.

RGPD4 RANBP2 RGPD8 NUP88 RGPD3 NUP133

3.25e-0838172612791264
Pubmed

The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity.

RGPD4 RANBP2 RGPD8 RGPD3

3.98e-088172421670213
Pubmed

Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis.

RGPD4 RANBP2 RGPD8 RGPD3

3.98e-088172427412403
Pubmed

Mice lacking Ran binding protein 1 are viable and show male infertility.

RGPD4 RANBP2 RGPD8 RGPD3

3.98e-088172421310149
Pubmed

The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2.

RGPD4 RANBP2 RGPD8 RGPD3

3.98e-088172422262462
Pubmed

Zap70 and downstream RanBP2 are required for the exact timing of the meiotic cell cycle in oocytes.

RGPD4 RANBP2 RGPD8 RGPD3

3.98e-088172428745977
Pubmed

Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.

RGPD4 RANBP2 RGPD8 RGPD3

7.14e-089172418394993
Pubmed

Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes.

RGPD4 RANBP2 RGPD8 RGPD3

7.14e-089172428100513
Pubmed

The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1.

RGPD4 RANBP2 RGPD8 RGPD3

7.14e-089172410601307
Pubmed

The cyclophilin-like domain mediates the association of Ran-binding protein 2 with subunits of the 19 S regulatory complex of the proteasome.

RGPD4 RANBP2 RGPD8 RGPD3

7.14e-08917249733766
Pubmed

Impairments in age-dependent ubiquitin proteostasis and structural integrity of selective neurons by uncoupling Ran GTPase from the Ran-binding domain 3 of Ranbp2 and identification of novel mitochondrial isoforms of ubiquitin-conjugating enzyme E2I (ubc9) and Ranbp2.

RGPD4 RANBP2 RGPD8 RGPD3

7.14e-089172428877029
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

UBR2 PSAP KIF4A TRRAP GCLC SUPT6H GCC2 IQCB1 NUP133 TASOR

1.16e-072121721033853758
Pubmed

The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes.

RGPD4 RANBP2 RGPD8 RGPD3

1.19e-0710172427160050
Pubmed

Parkin ubiquitinates and promotes the degradation of RanBP2.

RGPD4 RANBP2 RGPD8 RGPD3

1.19e-0710172416332688
Pubmed

Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin.

RGPD4 RANBP2 RGPD8 RGPD3

1.19e-071017248857542
Pubmed

Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability.

RGPD4 RANBP2 RGPD8 RGPD3

1.19e-0710172421859863
Pubmed

Homologous ribosomal protein genes on the human X and Y chromosomes: escape from X inactivation and possible implications for Turner syndrome.

RPS4Y2 RPS4X RPS4Y1

1.19e-07317232124517
Pubmed

Expression level of Rps4 mRNA in 39,X mice and 40,XX mice.

RPS4Y2 RPS4X RPS4Y1

1.19e-07317238187552
Pubmed

Relationship between the monosomy X phenotype and Y-linked ribosomal protein S4 (Rps4) in several species of mammals: a molecular evolutionary analysis of Rps4 homologs.

RPS4Y2 RPS4X RPS4Y1

1.19e-07317238808278
Pubmed

Inactivation of the Rps4 gene on the mouse X chromosome.

RPS4Y2 RPS4X RPS4Y1

1.19e-07317231783379
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

SIN3B RANBP2 NAA15 DOCK11 DSP MATR3 TF TTC7B SUPT6H SCN8A FMN2 TNKS KCNT1 TRAPPC9

1.21e-074751721431040226
Pubmed

RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism.

RGPD4 RANBP2 RGPD8 RGPD3

1.86e-0711172417069463
Pubmed

An Rtn4/Nogo-A-interacting micropeptide modulates synaptic plasticity with age.

RGPD4 RANBP2 RGPD8 RGPD3

1.86e-0711172435771867
Pubmed

T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1.

RGPD4 RANBP2 RGPD8 RGPD3

1.86e-0711172434110283
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

UBL7 RANBP2 PSAP DSP USP11 LAMA2 FSD2 NEB TTC3 SUPT6H NUP133 MACF1 TNKS ABLIM2

2.09e-074971721423414517
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

RGPD4 RANBP2 RGPD8 MYO5A MATR3 RPS25 RGPD3 MACF1 ABLIM2 RIMS2

2.57e-072311721016452087
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

RANBP2 NAA15 MYO5A DSP USP11 RPS4X ACP1 MATR3 CKAP5 KIF4A RPS25 CMAS TRRAP NKRF ARG1 RIF1 NUP133 PPP1R37 PDCD11 MACF1 UTP20 KIF5B ZMYM3

2.62e-0713531722329467282
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

RGPD8 MYO5A DSP RPS4X MATR3 TEX15 NEB NKRF MACF1 DNAH5

2.90e-072341721036243803
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

RGPD4 RANBP2 RGPD8 ATAD5 NUP88 CKAP5 KIF4A NKRF BPTF RIF1 RGPD3 KIF4B

3.62e-073701721222922362
Pubmed

Structure and function of ribosomal protein S4 genes on the human and mouse sex chromosomes.

RPS4Y2 RPS4X RPS4Y1

4.74e-07417238139551
Pubmed

Identification of a novel Ran binding protein 2 related gene (RANBP2L1) and detection of a gene cluster on human chromosome 2q11-q12.

RANBP2 RGPD8 RGPD5

4.74e-07417239480752
Pubmed

Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.

RGPD4 RANBP2 RGPD8 MYO5A DSP RPS4X MATR3 IST1 KIF4A RPS25 TXLNA RGPD3 KIF4B LRRFIP2 RGPD5

5.91e-076261721533644029
Pubmed

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.

RGPD4 RANBP2 RGPD8 TRRAP PHC1 BPTF SUPT6H RGPD3

7.17e-07146172823892456
Pubmed

Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.

RGPD4 RANBP2 RGPD8 RGPD3

7.56e-0715172414697343
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

RANBP2 MYO5A DSP RPS4X MATR3 CKAP5 RPS25 TRRAP NKRF ARG1 BPTF RIF1 SUPT6H NUP133 PDCD11 MACF1 UTP20 KIF5B XPO7

8.68e-0710241721924711643
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

OLAH SIN3B CYP26B1 DOCK11 DSP DISC1 TBC1D2 CKAP5 RPS25 NUDT12 FBXL7 SCN8A FMN2 UTP20 ANKRD18A LRRFIP2

8.83e-077361721629676528
Pubmed

Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia.

RPS4Y2 RPS4X RPS4Y1 MATR3 RPS25 THOC5 PDCD11

9.09e-07104172726167872
Pubmed

Use of a reverse transcriptase-polymerase chain reaction assay to analyze allele-specific expression in individual hippocampal neurons.

RPS4Y2 RPS4X RPS4Y1

1.18e-06517239562962
Pubmed

Maintenance of X inactivation of the Rps4, Zfx, and Ube1 genes in a mouse in vitro system.

RPS4Y2 RPS4X RPS4Y1

1.18e-06517237681608
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

RANBP2 ATAD5 USP11 ACP1 MATR3 SMC6 KIF4A XPA CMAS TRRAP NKRF THOC5 NCBP2 BPTF RIF1 SUPT6H NUP133 XPO7

3.18e-0610141721832416067
Pubmed

Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system.

RGPD4 RANBP2 RGPD8 RGPD3

3.94e-0622172427717094
Pubmed

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.

DSP USP11 RPS4X DISC1 MATR3 CKAP5 CCDC6 NKRF RIF1 CCDC88A ANGEL2 KIF5B TASOR

4.05e-065511721334728620
Pubmed

Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk.

TRGC1 TRGC2 PTPRC

4.10e-06717237477352
Pubmed

Embryonic growth and the evolution of the mammalian Y chromosome. II. Suppression of selfish Y-linked growth factors may explain escape from X-inactivation and rapid evolution of Sry.

RPS4Y2 RPS4X RPS4Y1

4.10e-06717237928394
Pubmed

An evaluation of the inactive mouse X chromosome in somatic cell hybrids.

RPS4Y2 RPS4X RPS4Y1

4.10e-06717238460399
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH17 DNAH5 DNAH11

4.10e-067172331178125
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

RC3H2 RANBP2 CMAS TRRAP NKRF NCBP2 BPTF SUPT6H ANGEL2 NUP133 ING4 TASOR

4.25e-064691721227634302
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

SIN3B RANBP2 NAA15 DSP ATAD5 MATR3 NUP88 CKAP5 IST1 KIF4A NKRF RIF1 NUP133 MACF1 KIF5B SMCR8 TASOR

4.36e-069341721733916271
Pubmed

The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.

RGPD4 RANBP2 RGPD8 BPTF RIF1 RGPD3

4.54e-0686172637253089
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

NAA15 MYO5A DSP RPS4X MATR3 PARP2 CKAP5 RPS25 CMAS NKRF THOC5 ARG1 TXLNA ANGEL2 NUP133 PDCD11 UTP20 KIF5B HSPA14 LRRFIP2

4.55e-0612571722036526897
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

UBR2 RANBP2 MYO5A DSP ATAD5 CCDC18 CCDC6 CCDC77 NUDT12 RIF1 CCDC88A PTPRC TTC7B NUP133 PPP1R37 FMN2 EIF2AK4 RELL1

5.07e-0610491721827880917
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

SIN3B RANBP2 GGNBP2 MYO5A ATAD5 PARP2 CKAP5 IST1 KIF4A CMAS TRRAP NKRF NCBP2 RIF1 SUPT6H RGPD3 CEP83 PDCD11 MACF1 UTP20 TASOR ZMYM3

5.22e-0614971722231527615
Pubmed

Physical mapping of 2000 kb of the mouse X chromosome in the vicinity of the Xist locus.

RPS4Y2 RPS4X RPS4Y1

6.54e-06817238468051
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

RC3H2 TBC1D2 CKAP5 IRAK2 CLSTN1 TTC3 TXLNA MACF1 TACC3 DNAH5

6.71e-063321721037433992
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

RGPD8 NUP88 CKAP5 NKRF RGPD3 NUP133 PDCD11 UTP20 TASOR LRRFIP2

6.71e-063321721025693804
Pubmed

Human transcription factor protein interaction networks.

SIN3B MYO5A ATAD5 USP11 KRT74 MATR3 NUP88 HIPK2 RELB RPS25 LHX8 TRRAP NKRF STAT2 BPTF RIF1 PAXIP1 PDCD11 CABIN1 TRAPPC9 ZMYM3

8.71e-0614291722135140242
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

RANBP2 DSP MATR3 CKAP5 TRRAP NCBP2 RIF1 SUPT6H PDCD11

9.28e-06272172931010829
Pubmed

Cloning and localization of the murine Xpct gene: evidence for complex rearrangements during the evolution of the region around the Xist gene.

RPS4Y2 RPS4X RPS4Y1

9.77e-06917239545634
Pubmed

Insights into specificity, redundancy and new cellular functions of C/EBPa and C/EBPb transcription factors through interactome network analysis.

RGPD4 RANBP2 RGPD8 MATR3 AK5 RGPD3

1.03e-0599172627746211
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

RANBP2 RPS4X ACP1 NUP88 RPS25 CMAS TRRAP RGPD3 NUP133 PDCD11 UTP20 KIF5B DNAH5 HSPA14

1.19e-057041721429955894
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

NAA15 MYO5A ATAD5 USP11 ACP1 CYP51A1 CCDC18 RPS25 CCDC77 CMAS TTC3 THOC5 TXLNA CCDC88A SUPT6H NUP133 PDCD11 MACF1 RELL1 SMCR8 HSPA14

1.58e-0514871722133957083
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

RGPD4 RANBP2 NAA15 RGPD8 MATR3 SMC6 NUP88 CKAP5 KIF4A SYF2 TF RGPD3 NUP133 KIF4B TACC3 ZMYM3 LRRFIP2 RGPD5

1.85e-0511551721820360068
Pubmed

Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.

RANBP2 DSP KRT74 RPS4X ACP1 MATR3 RTTN RPS25 NKRF ARG1 NCBP2 NUP133 PDCD11

2.01e-056411721336057605
Pubmed

Defining the membrane proteome of NK cells.

RANBP2 NAA15 MYO5A RPS4X RPS4Y1 MATR3 CNTRL CYP51A1 CKAP5 KIF4A CCDC77 CMAS TXLNA PTPRC GCC2 NUP133 KIF5B HSPA14

2.14e-0511681721819946888
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

ATAD5 PARP2 SMC6 CCDC18 CKAP5 KIF4A CCDC77 CMAS PHC1 TXLNA PAXIP1 KIF5B CABIN1

2.15e-056451721325281560
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

PSAP MYO5A DSP USP11 CKAP5 IST1 CCDC6 CMAS TTC3 TF BRWD3 TTC7B OSBPL1A LRP4 FMN2 MACF1 TNKS CABIN1 ECE2

2.21e-0512851721935914814
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

RANBP2 GGNBP2 RPS4X MATR3 RPS25 SYF2 TRRAP NKRF RIF1 NUP133 PDCD11 UTP20 TASOR ZMYM3 LRRFIP2

2.25e-058471721535850772
Pubmed

KIF4 regulates neuronal morphology and seizure susceptibility via the PARP1 signaling pathway.

KIF4A KIF4B

2.43e-052172236482480
Pubmed

Polymorphism of Tcrb and Tcrg genes in Biozzi mice: segregation analysis of a new Tcrg haplotype with antibody responsiveness.

TRGC1 TRGC2

2.43e-05217221973682
Pubmed

T cell-specific gamma genes in C57BL/10 mice. Sequence and expression of new constant and variable region genes.

TRGC1 TRGC2

2.43e-05217223486244
Pubmed

The multiple functions of kinesin-4 family motor protein KIF4 and its clinical potential.

KIF4A KIF4B

2.43e-052172230081192
InteractionRGPD4 interactions

RGPD4 RANBP2 RGPD8 RGPD3 RGPD5

9.44e-07221705int:RGPD4
InteractionSIRT7 interactions

RANBP2 NAA15 MYO5A DSP USP11 RPS4X NUP88 CKAP5 KIF4A TRRAP NKRF BPTF RIF1 SUPT6H NUP133 PDCD11 MACF1 UTP20 KIF5B ZMYM3 XPO7

1.30e-0674417021int:SIRT7
InteractionRGPD2 interactions

RGPD4 RANBP2 RGPD8 RGPD3 RGPD5

2.80e-06271705int:RGPD2
InteractionHECTD1 interactions

RPS4Y2 MYO5A ATAD5 TRAIP MATR3 SMC6 CKAP5 KIF4A RPS25 CMAS TRRAP NKRF DIRAS3 BPTF RIF1 TXLNA IQCB1 NUP133 PDCD11 MACF1 UTP20 TASOR HSPA14 LRRFIP2

2.80e-0698417024int:HECTD1
InteractionNUP62 interactions

RANBP2 RGPD8 DISC1 NUP88 TXLNA CCDC88A RGPD3 NUP133 KIF5B TACC3 RGPD5 XPO7

3.68e-0627317012int:NUP62
InteractionSIRT6 interactions

RANBP2 RGPD8 DOCK11 DSP USP11 MATR3 PARP2 NUP88 KIF4A CCDC6 TRRAP NKRF TXLNA SUPT6H IQCB1 NUP133 EDEM1 RGPD5

6.36e-0662817018int:SIRT6
InteractionBTF3 interactions

RGPD4 RANBP2 NAA15 RGPD8 MYO5A DSP RPS4X MATR3 SMC6 CKAP5 IST1 KIF4A RPS25 CMAS TXLNA RGPD3 NUP133 KIF4B LRRFIP2 RGPD5

1.40e-0579917020int:BTF3
InteractionRGPD8 interactions

RGPD4 RANBP2 RGPD8 DISC1 RGPD3 RGPD5

3.80e-05741706int:RGPD8
InteractionRGPD3 interactions

RGPD4 RANBP2 RGPD8 RGPD3 RGPD5

4.64e-05471705int:RGPD3
InteractionRGPD1 interactions

RGPD4 RANBP2 RGPD8 RGPD3 RGPD5

5.69e-05491705int:RGPD1
Cytoband2q12.3

RGPD4 RANBP2 GCC2

3.38e-051717232q12.3
CytobandXq24

DOCK11 AKAP14 NKRF C1GALT1C1

1.01e-04641724Xq24
Cytoband2q13

NT5DC4 RGPD8 RGPD3 RGPD5

1.29e-046817242q13
CytobandEnsembl 112 genes in cytogenetic band chrXq24

DOCK11 AKAP14 NKRF C1GALT1C1

2.53e-04811724chrXq24
CytobandXq13.1

RPS4X KIF4A ZMYM3

7.90e-04481723Xq13.1
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

RGPD4 RANBP2 RGPD8 TTC3 IFIT3 TTC7B RGPD3 TTC9 RGPD5

6.69e-081151199769
GeneFamilyLIM class homeoboxes

LHX8 LMX1A LMX1B

5.86e-05121193522
GeneFamilyS ribosomal proteins

RPS4Y2 RPS4X RPS4Y1 RPS25

7.10e-05341194728
GeneFamilyDyneins, axonemal

DNAH17 DNAH5 DNAH11

1.77e-04171193536
GeneFamilyRegulating synaptic membrane exocytosis family|PDZ domain containing

RIMS4 RIMS2

2.56e-0441192833
GeneFamilyEndogenous ligands|Minor histocompatibility antigens

RPS4Y1 NUP133 PDCD11 LY75

3.51e-04511194870
GeneFamilyGlycine receptors

GLRA2 GLRB

4.24e-0451192868
GeneFamilyEF-hand domain containing|Plakins

DSP MACF1

1.17e-0381192939
GeneFamilyNucleoporins

RANBP2 NUP88 NUP133

1.20e-033211931051
GeneFamilyAnkyrin repeat domain containing|POTE ankyrin domain containing

POTEB2 POTEB

3.20e-03131192685
GeneFamilyKinesins|Pleckstrin homology domain containing

KIF4A KIF4B KIF5B

3.43e-03461193622
GeneFamilyAnkyrin repeat domain containing

POTEB2 NUDT12 OSBPL1A ANKRD18A TNKS POTEB

5.34e-032421196403
GeneFamilyZinc fingers|Zinc fingers PARP-type|Poly(ADP-ribose) polymerases

PARP2 TNKS

5.48e-03171192684
CoexpressionLAZARO_GENETIC_MOUSE_MODEL_HIGH_GRADE_SMALL_CELL_NEUROENDOCRINE_LUNG_CARCINOMA_UP

ACSL6 ATAD5 CCDC18 CKAP5 KIF4A TTC3 PHC1 RIF1 ALDH1L2 RAD54B SCN8A PAXIP1 FMN2 KIF4B TACC3 PPIP5K2 RIMS2

2.68e-0668017217MM456
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

UBR2 DPYD RANBP2 CKAP5 CCDC6 TRRAP BPTF USP6 RIF1 FBXL7 GCC2 GLRB NUP133 MACF1 UTP20 TNKS PLCB4 PPIP5K2 TASOR

3.83e-0685617219M4500
CoexpressionGSE32986_UNSTIM_VS_CURDLAN_HIGHDOSE_STIM_DC_UP

CKAP5 IRAK2 RIF1 TXLNA CCDC88A RAD54B EIF2AK4 HSPA14 XPO7

7.37e-062001729M8614
CoexpressionTABULA_MURIS_SENIS_PANCREAS_PANCREATIC_STELLATE_CELL_AGEING

RPS4Y2 RPS4X RPS4Y1

2.27e-0591723MM3821
CoexpressionGSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP

DOCK11 CKAP5 BPTF RIF1 PRDM10 TTC7B MACF1 TNKS

2.62e-051801728M8239
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

GGNBP2 NAA15 MYO5A SMC6 HIPK2 BPTF NUDT12 RIF1 CCDC88A GCC2 RAD54B OSBPL1A KIF5B PPIP5K2 TASOR

3.01e-0565617215M18979
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#3

ATAD5 HLF SMC6 CCDC18 CKAP5 LHX8 NKRF BRWD3 COL24A1 RIF1 TTC7B GCC2 CEP83 MACF1 EIF2AK4

2.52e-0643217215Facebase_RNAseq_e10.5_Maxillary Arch_1000_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

RANBP2 MYO5A ATAD5 SMC6 CCDC18 CKAP5 NKRF RIF1 CCDC88A GCC2 CEP83 LRRFIP2

9.24e-0631117212Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500_K3

CACNB2 MYO5A ATAD5 CNTRL CYP51A1 SMC6 CKAP5 HIPK2 KIF4A CCDC77 NKRF PHC1 BPTF RIF1 CCDC88A LMX1B GCC2 GLRB IQCB1 RAD54B CEP83 SCN8A PAXIP1 MACF1 UTP20

2.88e-05125717225facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#4

EFCAB6 CCDC18 CKAP5 XPA LHX8 CCDC88A TTC7B GCC2 GLRB CEP83 MACF1

3.30e-0529817211Facebase_RNAseq_e10.5_Medial Nasal Eminence_1000_K4
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_500

EFCAB6 DOCK11 ATAD5 HLF CCDC18 CKAP5 IRAK2 LHX8 NKRF COL24A1 RIF1 GCC2 ABLIM2 EPHX4

5.02e-0549217214Facebase_RNAseq_e10.5_Maxillary Arch_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000

EFCAB6 DOCK11 ATAD5 HLF SMC6 CCDC18 CKAP5 IRAK2 LHX8 NKRF BRWD3 COL24A1 RIF1 TTC7B GCC2 CEP83 MACF1 EIF2AK4 TACC3 ABLIM2 EPHX4

5.29e-0598917221Facebase_RNAseq_e10.5_Maxillary Arch_1000
CoexpressionAtlasdev gonad_e12.5_M_GermCellTestis_Oct_top-relative-expression-ranked_1000

RPS4Y2 RPS4X CCDC18 NUP88 TEX15 NKRF PHC1 RIF1 GCLC IQCB1 PHF11 RAD54B NUP133 PDCD11 UTP20 RIMS2 HSPA14 GPN3

8.40e-0579517218gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_1000
CoexpressionAtlasdev gonad_e11.5_F_PrimGermCell_Oct_top-relative-expression-ranked_1000

RPS4Y2 DSP RPS4X CCDC18 NUP88 TEX15 NKRF PHC1 RIF1 GCLC PHF11 RAD54B NUP133 PDCD11 UTP20 RIMS2 HSPA14 GPN3

8.95e-0579917218gudmap_dev gonad_e11.5_F_PrimGermCell_Oct_1000
CoexpressionAtlasdev gonad_e13.5_M_GermCell_Oct_top-relative-expression-ranked_1000

RPS4Y2 RPS4X CCDC18 NUP88 TEX15 NKRF PHC1 RIF1 GCLC PHF11 RAD54B NUP133 PDCD11 UTP20 CABIN1 RIMS2 CATSPERG GPN3

1.06e-0481017218gudmap_dev gonad_e13.5_M_GermCell_Oct_1000
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500

CACNB2 MYO5A ATAD5 CNTRL CYP51A1 SMC6 CKAP5 HIPK2 KIF4A CCDC77 NKRF PHC1 BPTF RIF1 CCDC88A LMX1B GCC2 GLRB IQCB1 PHF11 RAD54B CEP83 SCN8A PAXIP1 MACF1 UTP20

1.22e-04145917226facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlasdev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_500

RPS4Y2 DSP CCDC18 TEX15 NKRF RIF1 GCLC IQCB1 PHF11 RAD54B NUP133 RIMS2

1.23e-0440617212gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_500
CoexpressionAtlasdev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_1000

RPS4Y2 NAA15 DSP ACP1 CCDC18 NUP88 KIF4A TEX15 NKRF PHC1 RIF1 GCLC IQCB1 PHF11 RAD54B NUP133 UTP20 RIMS2

1.28e-0482217218gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000

DPYD RANBP2 EFCAB6 ATAD5 CYP51A1 SMC6 CCDC18 CKAP5 LHX8 NKRF RIF1 GCC2 GLRB IQCB1 CEP83 LRP4 FMN2 UTP20 ABLIM2 RIMS2

1.43e-0498317220Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000_k-means-cluster#3

SMC6 CCDC18 CKAP5 LHX8 NKRF RIF1 GCC2 GLRB CEP83

1.85e-042461729Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5

ATAD5 SMC6 CCDC18 CKAP5 IFIT3 NKRF BRWD3 BPTF RIF1 SUPT6H GLRB CEP83 FMN2 MACF1 EIF2AK4

1.92e-0462917215Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_500_k-means-cluster#3

EFCAB6 HLF CCDC18 CKAP5 LHX8 NKRF COL24A1 RIF1 GCC2

2.42e-042551729Facebase_RNAseq_e10.5_Maxillary Arch_500_K3
CoexpressionAtlasdev gonad_e11.5_M_PrimGermCell_Oct_top-relative-expression-ranked_500

RPS4Y2 DSP RPS4X CCDC18 TEX15 RIF1 GCLC PHF11 RAD54B UTP20 RIMS2

2.58e-0437617211gudmap_dev gonad_e11.5_M_PrimGermCell_Oct_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_1000

ACSL6 EFCAB6 CCDC18 CKAP5 HIPK2 IRAK2 XPA LHX8 GRAMD2A CCDC88A TTC7B GCC2 GLRB CEP83 LRP4 MACF1 RELL1 ABLIM2 EPHX4

3.82e-0497917219Facebase_RNAseq_e10.5_Medial Nasal Eminence_1000
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_MedNas_2500_K1

EPHA6 MYO5A ATAD5 CNTRL SMC6 CKAP5 HIPK2 PHC1 NUDT12 RIF1 CCDC88A GCC2 GLRB RAD54B OSBPL1A CEP83 SCN8A MACF1 PLCB4 CATSPERG

3.83e-04106017220facebase_RNAseq_e10.5_Emin_MedNas_2500_K1
CoexpressionAtlasdev gonad_e13.5_M_GermCell_Oct_top-relative-expression-ranked_500

RPS4Y2 RPS4X CCDC18 TEX15 PHC1 RIF1 GCLC PHF11 RAD54B UTP20 RIMS2

4.00e-0439617211gudmap_dev gonad_e13.5_M_GermCell_Oct_500
CoexpressionAtlasdev gonad_e11.5_F_PrimGermCell_Oct_k-means-cluster#3_top-relative-expression-ranked_1000

RPS4Y2 RPS4X NUP88 PHC1 RIF1 RAD54B NUP133 PDCD11 UTP20 RIMS2 HSPA14 GPN3

4.08e-0446317212gudmap_dev gonad_e11.5_F_PrimGermCell_Oct_k3_1000
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3

RANBP2 DOCK11 ATAD5 SMC6 CCDC18 CKAP5 TTC3 NKRF PHC1 RIF1 CEP83 PAXIP1 LRP4

4.12e-0453217213Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ATAD5 DISC1 CNTRL CCDC18 CKAP5 KIF4A CCDC88A FCGBP PTPRC TACC3

3.23e-091871721073931a5ea73799095daff100b5f18853c57c74dc
ToppCellCTRL-Myeloid|CTRL / Disease state, Lineage and Cell class

DPYD PSAP MYO5A DOCK11 EMILIN2 HIPK2 CCDC88A PTPRC TREM1

8.52e-08199172970b89a930709fdb91fde6f96106add8455b11618
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

NAA15 MATR3 CNTRL HIPK2 TTC3 BPTF GCC2 OSBPL1A DNAH5

8.52e-081991729fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RANBP2 MATR3 CKAP5 ABCA9 CCDC88A MACF1 TNKS TASOR

4.36e-071761728749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellControl-Myeloid|Control / group, cell type (main and fine annotations)

PSAP MYO5A DOCK11 DISC1 EMILIN2 CCDC88A PTPRC TREM1

8.10e-0719117289c4acc5f3c2f9c0c5520863bb22f391774372347
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

NAA15 CNTRL CCDC18 HIPK2 TTC3 BPTF CCDC88A GCC2

1.06e-06198172876d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCellParenchymal-NucSeq-Immune_Myeloid|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PSAP MYO5A DOCK11 DISC1 EMILIN2 CCDC88A PTPRC TTC7B

1.10e-0619917287ee2805fd9143eba11bf6832267b62189683608b
ToppCell(01)_IL1RL1+-(2)_GFP_FOXI1|(01)_IL1RL1+ / shred by cell type by condition

NAA15 CYP26B1 SMC6 TTC3 BPTF CCDC88A GCC2 ANKRD18A

1.10e-061991728a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CCL|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PSAP EMILIN2 IRAK2 RELB CCDC77 TREM1 RELL1 IL1B

1.10e-06199172851be0e3a91d1f25454b56d55ef6342ef8e8df4e8
ToppCellfacs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EMILIN2 MCF2 FSD2 CLSTN1 ABCA9 CCDC106 ALOXE3

4.32e-061691727454b92b9b67299a64278c010db033ca5b9d217a0
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_ILC|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

COL6A6 TRGC2 CNTRL CKAP5 KIAA1586 NUDT12 LY75

5.24e-061741727e70cc623a3a6aceec813ed852fec0c4240561133
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

COL6A6 TRGC2 CNTRL CKAP5 KIAA1586 NUDT12 LY75

5.24e-0617417279bb8159a62640756d18ecbade3bf32bcbb7dd590
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_ILC-NK_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

COL6A6 TRGC2 CNTRL CKAP5 KIAA1586 NUDT12 LY75

5.24e-061741727b6725086fe5a2b057c7c495ec63c970ac52c2580
ToppCelldroplet-Marrow-nan-3m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATAD5 HLF TTC3 GCC2 MACF1 LY75 TASOR

7.03e-061821727e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCelldroplet-Marrow-nan-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATAD5 HLF TTC3 GCC2 MACF1 LY75 TASOR

7.03e-0618217271710eab3037a87609d21838be2d2d29c3bc36651
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATR3 CNTRL CCDC88A PTPRC GCC2 MACF1 TASOR

7.55e-0618417271154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

MYO5A DOCK11 LAMA2 KIAA1586 ABCA9 ALDH1L2 FHL5

7.55e-06184172767164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPHA6 DOCK11 CLSTN1 FCGBP DNAH17 PLCB4 RIMS2

8.39e-061871727c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_CCL3+|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PSAP MYO5A TRAIP IFIT3 CCDC88A TREM1 IL1B

8.99e-0618917271f4fe19e500bfedd48b1f34827a44e796f6db3e1
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_CCL3+-Alveolar_macrophage_CCL3+_L.1.0.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PSAP MYO5A TRAIP IFIT3 CCDC88A TREM1 IL1B

8.99e-061891727bfa1dfc93ad33a9dbef316c0591b950d062b35eb
ToppCellCOVID-19-Heart-Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

DPYD MYO5A DOCK11 DISC1 EMILIN2 FCGBP PTPRC

8.99e-0618917272586f4088721c5debec86c2b211b739fd33713eb
ToppCellCOVID-19-lung-Macrophage_PPARGhi_CD5Lhi|lung / Disease (COVID-19 only), tissue and cell type

PSAP MYO5A DOCK11 TBC1D2 EMILIN2 CCDC88A PTPRC

9.63e-061911727dab953682b8c9ed680a799161f837f792a7e4f33
ToppCellControl-Myeloid-Monocyte-derived_macrophages|Control / group, cell type (main and fine annotations)

PSAP MYO5A DOCK11 DISC1 EMILIN2 CCDC88A PTPRC

1.03e-051931727a6b3bd01e585e2e3fbe9bf693a2e385773123f8e
ToppCellsevere-CD4+_Tcm|World / disease stage, cell group and cell class

ACSL6 GGNBP2 RPS4X RPS4Y1 RPS25 GCC2 AK5

1.03e-051931727be0370b2f0093ad0b9d876297bd196d0160f3d99
ToppCellhuman_hepatoblastoma-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ATAD5 RTTN CCDC18 CKAP5 KIF4A CCDC77 TACC3

1.03e-0519317274b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PSAP COL6A6 TTC3 RIF1 FMN2 MACF1 KIF5B

1.10e-0519517277796ea9247f4c63762f0de8490fed08b9717fa23
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PSAP COL6A6 TTC3 RIF1 FMN2 MACF1 KIF5B

1.10e-0519517273e519cffa6144a62b06124642a14c9ff39b76554
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-T_lymphocytic-T_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ACSL6 THEMIS RPS4X TRGC2 RPS25 PTPRC GCC2

1.14e-051961727ecbc2baec21e85e6d8eac32d46f2c966fc35e223
ToppCellCOVID-19-lung-Macrophage_CD163hi_MERTKhi|COVID-19 / Disease (COVID-19 only), tissue and cell type

DPYD PSAP MYO5A DOCK11 EMILIN2 CCDC88A PTPRC

1.14e-0519617277026c1fc33425e5476063d17c79e4b79356a9e01
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_neuro-secretory|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CKAP5 NEB DIRAS3 LMX1B SCN8A FMN2 RIMS2

1.18e-051971727ff4df77117165b6b25315e29b0722cc136eba607
ToppCellChildren_(3_yrs)-Immune|Children_(3_yrs) / Lineage, Cell type, age group and donor

PSAP MYO5A DOCK11 DISC1 EMILIN2 CCDC88A PTPRC

1.18e-051971727f18807124b91310fcd84238484a80ecdba684679
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DPYD CACNB2 MAOA COL6A6 LAMA2 COL24A1 MACF1

1.18e-0519717270034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DPYD CACNB2 MAOA COL6A6 LAMA2 COL24A1 MACF1

1.18e-05197172711a4c417f035e554431a8f03be13b5eefa3530c0
ToppCellAdult-Immune|Adult / Lineage, Cell type, age group and donor

PSAP MYO5A DOCK11 DISC1 EMILIN2 CCDC88A PTPRC

1.22e-0519817279bfd7b88aa646eaf5eddb15cf985c7ca910cb35e
ToppCellLPS_only-Epithelial_airway|LPS_only / Treatment groups by lineage, cell group, cell type

DSP AKAP14 TF ARG1 FCGBP ATP12A DNAH5

1.22e-051981727ba090210392e001a3f7bdf09371b3f0e0c8c7ef3
ToppCellLPS_only-Epithelial_airway-airway_epithelial|LPS_only / Treatment groups by lineage, cell group, cell type

DSP AKAP14 TF ARG1 FCGBP ATP12A DNAH5

1.22e-051981727e035380578c01b0243bfef29ca9b50cc17cce771
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NT5DC4 PSAP MYO5A DISC1 EMILIN2 CCDC88A TTC7B

1.22e-0519817270b41b3d6c2db795320e8b65d40d85fb8b618cc34
ToppCellLPS_only-Epithelial_airway-airway_epithelial-Airway-Club|LPS_only / Treatment groups by lineage, cell group, cell type

DSP AKAP14 TF ARG1 FCGBP ATP12A DNAH5

1.26e-051991727165ac94b2d56072ad43358b5127d77555221e2d8
ToppCellLPS_anti-TNF-Endothelial-Endothelial-FOXM1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ATAD5 TRAIP CNTRL CCDC18 CKAP5 KIF4A TACC3

1.26e-05199172798575fcce726589e93fbb4df1aab03e57cb56076
ToppCellSepsis-Leuk-UTI-Lymphocyte-T/NK-CD8+_Tcm|Leuk-UTI / Disease, condition lineage and cell class

ACSL6 THEMIS RPS4Y1 RPS25 TTC3 GCC2 TTC9

1.26e-0519917276a1d84f61e1efaab541910926d6911122372659f
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-FOXM1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ATAD5 CNTRL CCDC18 CKAP5 KIF4A CCDC88A TACC3

1.30e-0520017274cfe08878a6981bf7b3567f9e82192d8f060ddde
ToppCellControl_saline-Endothelial-Endothelial-FOXM1|Control_saline / Treatment groups by lineage, cell group, cell type

ATAD5 CNTRL CCDC18 CKAP5 KIF4A CCDC88A TACC3

1.30e-0520017279bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell|343B / Donor, Lineage, Cell class and subclass (all cells)

THEMIS TRGC1 TRGC2 MCF2 PTPRC AK5

1.49e-051361726b4a934feea46eeb10d407d1545bd225173078792
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-CR-CR_Lhx5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COL6A6 SLC27A6 DSP TEX15 LMX1A

1.76e-0583172575b27d91a4473286f4b40027e96ac5246f5abe5b
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-CR|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COL6A6 SLC27A6 DSP TEX15 LMX1A

1.76e-058317251ab68323518adc7fd0a459b41fad12d60f97eb5c
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNB2 ABCA9 GCLC LMX1A LMX1B RIMS2

3.12e-051551726498e52e2364ff44d3c0c707ba22468217031f5bd
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TEX15 LHX8 NKRF GRAMD2A COL24A1 GLRA2

4.58e-051661726548d0d6c0ffd564036ddba78620734220ebb73d7
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TEX15 LHX8 NKRF GRAMD2A COL24A1 GLRA2

4.58e-05166172680e164a89d22098cabe4a99a78283ba69ea0561e
ToppCellfacs-Liver-Hepatocytes-24m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EMILIN2 MCF2 FSD2 CLSTN1 ABCA9 ALOXE3

4.89e-0516817264ae9e9d93bcd6f4d5815e57fd5afa7a3398a0ec1
ToppCellfacs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EMILIN2 MCF2 FSD2 CLSTN1 ABCA9 ALOXE3

4.89e-05168172604e168fe1d6f5f9e3d3bf9d7c13e800e3594868a
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RTTN CCDC18 KIF4A PRDM10 TREM1 TACC3

4.89e-05168172652fd65024af8683db11d931f7563cbe8eb815d1c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ATAD5 KIF4A TEX15 GLRB RAD54B TACC3

5.06e-0516917260bc8ef341ce307b19018d4ac8de0a4d04254209d
ToppCellnormal-na-Lymphocytic_T-T4_em-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

THEMIS RPS4Y1 HLF PTPRC GCC2 MACF1

5.40e-05171172661318a7aaf3bd8bdd28f8a8614ab4fdf2964b3a3
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Microglia/Mac|metastatic_Lymph_Node / Location, Cell class and cell subclass

DISC1 NEB COL24A1 FCGBP TTC7B MUC5AC

5.58e-051721726f673a2e697b46e7cfa4186cb3fb2b98e3c83703e
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATAD5 TRAIP CKAP5 KIF4A RIF1 RAD54B

5.58e-0517217262b6cd84c946b1e800caba452ae70145ea285fec1
ToppCellfacs-MAT-Fat-18m-Lymphocytic-T_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DISC1 IRAK2 KIF4A ARG1 LY75 PDE11A

5.76e-05173172697391a763c17ce0107c9e2386e88c417ac75a72e
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD4-Tnaive/CM_CD4|GI_small-bowel / Manually curated celltypes from each tissue

RPS4X RPS25 GRAMD2A AK5 KIF4B ANKRD18A

6.14e-0517517264b77e9cf712c9e3b4fb68462a96aea47be124e8d
ToppCellControl-Lymphocyte-T_NK-CD8_TCM|Control / Disease, Lineage and Cell Type

ACSL6 THEMIS RPS4X TRGC2 RPS25 GCC2

6.33e-0517617261a7948eb86ee1da607db4d0576312b2859d94523
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-conventional_dendritic_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MAOA RPS4X CNTRL LMX1B SCN8A DNAH5

6.33e-051761726b8264cdda75c5145d8bf8ae00b3e05393fe9a92b
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MAOA RPS4X CNTRL LMX1B SCN8A DNAH5

6.33e-051761726e08e7a6dd0208acfbb8646d71915af822a64b5de
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MAOA RPS4X CNTRL LMX1B SCN8A DNAH5

6.33e-0517617264aee9fdada077db7e531684ab938153f84dc8146
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ERICH3 MATR3 TRGC1 TRGC2 IFIT3 MACF1

6.54e-051771726d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCellCOVID-19_Severe-CD4+_CTL|COVID-19_Severe / disease group, cell group and cell class

THEMIS TRGC1 TRGC2 LAMA2 PTPRC EPHX4

6.54e-05177172634e9455790bae905dd91923792f4109d18b7686e
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ERICH3 MATR3 TRGC1 TRGC2 IFIT3 MACF1

6.54e-051771726f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CACNB2 SLC27A6 LAMA2 LHX8 ABCA9 COL24A1

6.54e-0517717269ec7f1e64312d26d434b3312b58386715dbad644
ToppCellCOVID-19_Mild-Lymphoid_T/NK-NK_activated|COVID-19_Mild / Disease group, lineage and cell class

ERICH3 MATR3 TRGC1 TRGC2 IFIT3 MACF1

6.54e-0517717266978a22fef40c8b455342373abe7593f5ede0fa4
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CACNB2 SLC27A6 LAMA2 LHX8 ABCA9 COL24A1

6.54e-051771726016277dfd59b1793fddaaadc2b3f41622d76ce3a
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

ERICH3 MATR3 TRGC1 TRGC2 IFIT3 MACF1

6.54e-051771726936ab2b180a052387124f68d0c7f41c0b164e748
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ERICH3 MATR3 TRGC1 TRGC2 IFIT3 MACF1

6.54e-051771726d5aeda113afaa2425874394610344570c9078478
ToppCelldroplet-Lung-LUNG-30m-Myeloid-intermediate_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PSAP RPS4X EMILIN2 RPS25 PTPRC IL1B

6.74e-0517817263c1246dccdebd6f504ffdfd6eba3a676db9d2e8a
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RANBP2 CNTRL IFIT3 TNKS PLCB4 TASOR

6.74e-05178172601dafd19de04eff459253eaa9a35debf8f3deedf
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Intermediate_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PSAP RPS4X EMILIN2 RPS25 PTPRC IL1B

6.74e-05178172625a4545dbef4246cf6d27b9b5dde24881da6887e
ToppCellBronchial_Biopsy-Immune-Neutrophils|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

THEMIS DOCK11 PTPRC TREM1 IL1B VSTM1

6.95e-0517917268c50e13927c09de05c86cd90dd6f71cee004b0d3
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_monocyte_(14)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TRGC1 TRGC2 PTPRC TREM1 IL1B VSTM1

7.39e-0518117263457c1d431db4282be5a6243119e48960748ede7
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTRL ABCA9 CCDC88A PTPRC GCC2 MACF1

7.62e-051821726f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PSAP EMILIN2 CCDC88A PTPRC LY75 IL1B

7.62e-05182172694d061b7b5ebbfc564c644bc8b2d52341927145d
ToppCellPBMC-Mild-cDC_9|Mild / Compartment, Disease Groups and Clusters

PSAP RGPD8 MATR3 IFIT3 SCN8A UTP20

8.10e-0518417262e0c9a2c40c892a2d435eafb31f1f838de9baf15
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTRL ABCA9 CCDC88A PTPRC GCC2 MACF1

8.34e-0518517267adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ATAD5 TRAIP CCDC18 CKAP5 KIF4A TACC3

8.34e-05185172630e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCelldroplet-Spleen-nan-3m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS4X SMC6 RPS25 PXK MACF1 TASOR

8.59e-05186172626f1e9930adf2fe4af0819e56f69915bd8330e4a
ToppCellNasal_Brush-Immune-Neutrophils|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

DPYD TBC1D2 KIAA1586 PRDM10 PDCD11 SMCR8

8.59e-051861726f5aa91dbef29f7efa2b9a728c6539d7541340cd4
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-Granular_Neuron_CB_Gabra6|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARG1 LMX1A AK5 GLRA2 TMEM145 SCN8A

8.59e-051861726d6c8ce2a32c218dcc63d861cc247152430ed3c8c
ToppCelldroplet-Spleen-nan-3m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS4X SMC6 RPS25 PXK MACF1 TASOR

8.85e-05187172691c8e93bde0d1d1a4e324b0acf2afda00f4fb3bf
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ATAD5 TRAIP KIF4A FBXL7 RAD54B TACC3

8.85e-051871726e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

CACNB2 EPHA6 LAMA2 ABCA9 COL24A1 FBXL7

8.85e-051871726bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ATAD5 TRAIP KIF4A FBXL7 RAD54B TACC3

8.85e-051871726cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

CACNB2 COL6A6 LAMA2 ABCA9 FBXL7 MACF1

8.85e-05187172692d468dde81125d51daf7abd4703741abe1ab91c
ToppCelldroplet-Spleen-nan-3m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS4X SMC6 RPS25 PXK MACF1 TASOR

8.85e-051871726382db691eb0b3e089e816bed3d6699cc2d4e1bda
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_CCL3+-Alveolar_macrophage_CCL3+_L.1.0.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PSAP TRGC1 EMILIN2 CCDC88A TREM1 IL1B

8.85e-0518717267b24a324335c30c4b37795c43611b297274c804b
ToppCelldroplet-Marrow-nan-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS4Y2 ATAD5 CNTRL PXK GCC2 LY75

8.85e-05187172614c239af77116d28d511dea754b6150d20488080
ToppCellControl-Fibroblasts-Adventitial_FB|Control / group, cell type (main and fine annotations)

CACNB2 EPHA6 LAMA2 ABCA9 FBXL7 LMX1A

9.11e-051881726706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCellControl|World / Disease state, Lineage and Cell class

RANBP2 PSAP HIPK2 IRAK2 SUPT6H IL1B

9.38e-051891726fb8dddd3b901081c6bb9ed6f32dafc5cce5f30be
ToppCellsystemic_lupus_erythematosus-flare-Myeloid-classical_monocyte-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

DPYD PSAP RPS4Y1 EMILIN2 IFIT3 CCDC88A

9.38e-051891726cce6602ad68c177985a5e43cfb2776d615cfbca0
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPHA6 CLSTN1 FCGBP DNAH17 PLCB4 RIMS2

9.66e-0519017261cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCellpdx-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ATAD5 CCDC18 CKAP5 KIF4A CCDC77 TACC3

9.66e-051901726d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CNTRL CCDC18 CKAP5 KIF4A CCDC88A TACC3

9.66e-051901726cd37ccd30c27cf65eda0a9165f35b7672f5acaf6
ToppCellnucseq-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK-CD8_T|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

THEMIS RPS4X TRGC1 TRGC2 RPS25 PTPRC

9.94e-051911726f7a42a9d7493ea25cd8bd297c22e49e4bad7f0a4
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSP MATR3 CNTRL BRWD3 KIF5B TASOR

9.94e-05191172660c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RPS4X RPS4Y1 RPS25 TTC3 GCC2 AK5

9.94e-051911726f398344aaa79fc93d792e241b634a6afe4aff33d
ToppCellControl-Lymphoid-T_Cytotoxic|Lymphoid / Disease state, Lineage and Cell class

THEMIS RPS4X TRGC1 TRGC2 RPS25 PTPRC

9.94e-051911726ff7204f9b645233548cf804cf6fe0c86417be87f
DiseaseMyopathy

MAOA ARG1 EIF2AK4 IL1B

2.20e-05301634C0026848
DiseaseAmino Acid Metabolism, Inherited Disorders

ARG1 GCLC EIF2AK4

4.54e-05131633C0750905
DiseaseAmino Acid Metabolism, Inborn Errors

ARG1 GCLC EIF2AK4

4.54e-05131633C0002514
DiseaseHair Diseases

ARG1 EIF2AK4

9.07e-0531632C0018500
DiseaseSchizophrenia

ACSL6 DPYD CACNB2 MAOA DISC1 ACP1 LAMA2 TRRAP TF GCLC LMX1A LMX1B TREM1 IL1B RIMS2

1.21e-0488316315C0036341
Diseaseresponse to radiation

SLC27A6 EMILIN2 BRWD3 PTPRC DNAH5

1.31e-04881635GO_0009314
Diseasedry eye syndrome (is_implicated_in)

IL1B MUC5AC

1.81e-0441632DOID:10140 (is_implicated_in)
DiseaseKartagener syndrome (is_implicated_in)

DNAH5 DNAH11

1.81e-0441632DOID:0050144 (is_implicated_in)
DiseaseIntellectual Disability

NAA15 DISC1 RTTN KIF4A XPA TRRAP BRWD3 BPTF SCN8A MACF1

2.02e-0444716310C3714756
DiseaseMajor Depressive Disorder

MAOA DISC1 ACP1 HLF EDEM1 IL1B PDE11A

4.22e-042431637C1269683
DiseaseMental Retardation, X-Linked

MAOA BRWD3 ZMYM3

5.44e-04291633C1136249
DiseaseUnipolar Depression

MAOA DISC1 ACP1 HLF EDEM1 IL1B PDE11A

6.17e-042591637C0041696
Diseaseliver disease (biomarker_via_orthology)

DPYD ARG1

6.25e-0471632DOID:409 (biomarker_via_orthology)
DiseaseImmune System Diseases

ARG1 EIF2AK4

6.25e-0471632C0021053
DiseaseMalignant neoplasm of breast

DPYD MAOA RPS4X SMC6 LAMA2 TTC3 THOC5 RIF1 PTPRC NUP133 TREM1 MACF1 UTP20 IL1B HSPA14

9.42e-04107416315C0006142
Diseasehepatitis C (is_marker_for)

STAT2 TREM1 IL1B

9.51e-04351633DOID:1883 (is_marker_for)
Diseaseaspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement

DPYD GGNBP2 NUP88 EMILIN2 BPTF AK5 MACF1 TNKS

9.84e-043641638EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
DiseaseSilicosis

ARG1 IL1B

1.06e-0391632C0037116
Diseaseureteral obstruction (implicated_via_orthology)

RELB IL1B

1.06e-0391632DOID:5199 (implicated_via_orthology)
Diseaseencephalitis (biomarker_via_orthology)

SYF2 IL1B

1.06e-0391632DOID:9588 (biomarker_via_orthology)
Diseasevisceral heterotaxy (implicated_via_orthology)

OSBPL1A DNAH5 DNAH11

1.12e-03371633DOID:0050545 (implicated_via_orthology)
Diseaselung carcinoma

UBR2 COL6A6 ATAD5 ACTRT2 BPTF RIF1 AK5 DNAH11 XPO7

1.50e-034821639EFO_0001071
DiseaseBehavior Disorders

MAOA LMX1B

1.93e-03121632C0004930
DiseaseMental disorders

MAOA LMX1B

1.93e-03121632C0004936
DiseaseMouth Diseases

CYP26B1 HSPA14

1.93e-03121632C0026636
DiseaseMental Disorders, Severe

MAOA LMX1B

1.93e-03121632C4046029
Diseaseevent free survival time, type 1 diabetes mellitus, autoantibody measurement

ACTRT2 PXK

1.93e-03121632EFO_0000482, EFO_0004866, MONDO_0005147
DiseaseDiagnosis, Psychiatric

MAOA LMX1B

1.93e-03121632C0376338
Diseaseepilepsy (implicated_via_orthology)

KIF4A SCN8A KIF4B ATP12A KCNT1

2.16e-031631635DOID:1826 (implicated_via_orthology)
Diseasehomostachydrine measurement

ACSL6 PLCB4

2.27e-03131632EFO_0021164
Diseaserhinitis (biomarker_via_orthology)

IL1B MUC5AC

2.27e-03131632DOID:4483 (biomarker_via_orthology)
Diseasetetralogy of Fallot (implicated_via_orthology)

PHC1 DNAH5

2.64e-03141632DOID:6419 (implicated_via_orthology)
DiseaseKartagener syndrome (implicated_via_orthology)

DNAH5 DNAH11

2.64e-03141632DOID:0050144 (implicated_via_orthology)
Diseasebreastfeeding duration

SLC27A6 PHF11

2.64e-03141632EFO_0006864
Diseasesevere aplastic anemia

DPYD SLC27A6

3.04e-03151632EFO_0006927
Diseaseheel bone mineral density, urate measurement

THEMIS EPHA6 COL24A1 TTC9 PDE11A

3.48e-031821635EFO_0004531, EFO_0009270
Diseasecortical thickness

SLC27A6 LAMA2 FSD2 ACTRT2 CMAS PXK CCDC88A FBXL7 LMX1A LRP4 FMN2 MACF1 KIF5B TACC3

3.61e-03111316314EFO_0004840
DiseaseAlzheimer's disease (implicated_via_orthology)

CYP51A1 IL1B TM2D1

3.89e-03571633DOID:10652 (implicated_via_orthology)
Diseaseotitis media (biomarker_via_orthology)

IL1B MUC5AC

3.91e-03171632DOID:10754 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
LKEGQTLDVKCDYTL

TREM1

31

Q9NP99
EKGLKQIDEYFSKCV

AKAP14

76

Q86UN6
EKCLYEVGRDDNSKK

ATAD5

431

Q96QE3
ITLKDKKLCYDQGIS

CATSPERG

826

Q6ZRH7
ENLCVYKGKLLEKET

ERICH3

321

Q5RHP9
GGKKFKYIENLEKCV

CNTRL

111

Q7Z7A1
KYIENLEKCVKLEVL

CNTRL

116

Q7Z7A1
KNRELEEEATGYKKC

ANKRD18A

696

Q8IVF6
LKLVCDEIYNIKVEK

EIF2AK4

1616

Q9P2K8
GLVDDIKKKLCYVAL

ACTRT2

211

Q8TDY3
CGKEAIRIKNLKKEY

ABCA9

476

Q8IUA7
IRIKNLKKEYAGKCE

ABCA9

481

Q8IUA7
LKKEYAGKCERVEAL

ABCA9

486

Q8IUA7
LEKLLQYCETGVKEG

ALDH1L2

776

Q3SY69
LLKKLELYKEACEGQ

CCDC77

76

Q9BR77
YGDKLIDKKDCDLFQ

DNAH11

2746

Q96DT5
KKQCKELLSLIYERE

BRWD3

1306

Q6RI45
CTGLKALLYLKSIEE

DPYD

831

Q12882
KSCGKLLNAEYISKD

ABLIM2

181

Q6H8Q1
ELETYKLKCKALQEE

CCDC6

76

Q16204
EKVYLCQKLKGLEAE

CEP83

216

Q9Y592
SGKLADKKVIDCLYT

CLSTN1

546

O94985
DKKVIDCLYTCKEGL

CLSTN1

551

O94985
EYICSHDKEKTKILG

ANGEL2

136

Q5VTE6
KIYLKGECLKEISES

BPTF

1541

Q12830
KISEDKQLAVCLKYA

C1GALT1C1

216

Q96EU7
KCEDIGKKLLYLEDQ

DISC1

781

Q9NRI5
KDRYCEKDGEVISKK

CACNB2

631

Q08289
LLEKLKEQECDVKDY

ARG1

36

P05089
EVAKKCVEDLALYLK

RC3H2

96

Q9HBD1
CDKNEEKSLYKGLLS

RAD54B

611

Q9Y620
IYKLKEQLLDCEGED

RANBP2

131

P49792
SACLKLFQEKKEEGY

PADI1

496

Q9ULC6
IYKLKEQLLDCEGED

RGPD5

131

Q99666
IYKLKEQLLDCEGED

RGPD8

131

O14715
TGGEELYLLCDKVQK

RELB

316

Q01201
LLLYGADIESKNKCG

POTEB2

221

H3BUK9
KAGYQSLKKIEDCIR

PARP2

276

Q9UGN5
CEEEIAKLYKQLDDK

KIF5B

421

P33176
KKICELYAKVLGSQE

MAOA

371

P21397
GEKYECALKRASIKI

PAXIP1

146

Q6ZW49
EDKIKLLKAAFLQYC

NUP133

516

Q8WUM0
LGLKEKNLYLSCVLK

IL1B

176

P01584
YQKCGLKRKSEEIEN

HIPK2

126

Q9H2X6
GRCVKVDLSEKYKKL

MATR3

561

P43243
EQEKLLKKSCTLYVG

NCBP2

31

P52298
AKEICQKYLEKGAGR

IRAK2

451

O43187
AYNILIGELDCSKEK

GGNBP2

226

Q9H3C7
EYLESCLQKVKELGG

AK5

36

Q9Y6K8
IKDILDSLGYSKCVL

EPHX4

151

Q8IUS5
QKYKVRCTAELGELL

ALOXE3

51

Q9BYJ1
DGKEKYRGLKNNCLE

ATP12A

26

P54707
IREKLQCTQGKDYLD

CYP26B1

251

Q9NR63
KYGVCLIGLKREDNK

KCNT1

571

Q5JUK3
EKLLETLYGTKKSCV

ECE2

456

P0DPD6
NKTLSKEIGIYKESC

CCDC88A

866

Q3V6T2
GEKTLFHLCKILKYE

KIAA1586

651

Q9HCI6
KGDEFVLKEGQLLCK

LMX1A

131

Q8TE12
VLKEGQLLCKGDYEK

LMX1A

136

Q8TE12
QLLCKGDYEKERELL

LMX1A

141

Q8TE12
EIDKLTGYKTKSLLC

PDE11A

311

Q9HCR9
LSKCGEKYNDIDLTI

GCLC

336

P48506
LKYVCKRKGEKLNDA

LY75

481

O60449
NSCGLEIVDKYLLKV

LHX8

76

Q68G74
FDIKKEDIEYGNCTK

GLRB

231

P48167
EVNLKKYSGCLKDIE

LAMA2

2486

P24043
LLELDTKYANKTCGL

MUC5AC

196

P98088
LKDCYIHLKVSLDKG

PRDM10

246

Q9NQV6
KELGKCKNILAKYEA

HLF

276

Q16534
VEGYIQDKSKKKLCA

OSBPL1A

756

Q9BXW6
LNCLGKKEEAYELVR

NAA15

56

Q9BXJ9
KIGALEKQKEYIACL

LRRFIP2

486

Q9Y608
ETLGKLETQYCKLKE

MACF1

656

Q9UPN3
CLDLKGEKLDYKTCE

PPP1R37

111

O75864
VKVYLLDNGVCIAKK

RIMS2

1296

Q9UQ26
SGCLKKTLEDLEKYV

NT5DC4

181

Q86YG4
IYKLKEQLLDCEGED

RGPD3

131

A6NKT7
EKDEIIKLYSCIIGN

CKAP5

1606

Q14008
CTASLLGKKYVLKDD

FHL5

11

Q5TD97
FKKLTKAICGLIDDY

GPN3

211

Q9UHW5
EKDCRYSKGLVLKEK

CABIN1

186

Q9Y6J0
EKNSKESKGCIYLDA

DOCK11

211

Q5JSL3
VKDADGVLCRYKKIL

CCDC106

176

Q9BWC9
LKKSLAICEKALAEY

DNAH17

1556

Q9UFH2
KEECQQLIIKYDLKS

EFCAB6

1361

Q5THR3
CGLYKSELEILKEKL

CCDC18

291

Q5T9S5
YLAKNCTKLKSLDIG

FBXL7

396

Q9UJT9
LEKKYQKEEFCGLLS

FCGBP

1451

Q9Y6R7
ELEKKYQKEEFCGLL

FCGBP

2651

Q9Y6R7
LDKVEAYRCGLKKIK

DSP

801

P15924
YLQLKERCIKDEETG

DSP

2426

P15924
KKCYLEQKTVCGENL

CYP51A1

341

Q16850
IQKKYECELENLRKA

GCC2

291

Q8IWJ2
LLQAAKCYEKELGRL

IFIT3

431

O14879
DILQSLEKYTKVKCG

EDEM1

516

Q92611
FILKEEKELGYCTKH

GLRA2

221

P23416
LLKELLKYSKDCEGS

MCF2

641

P10911
ELKIVADQLCAKYSK

IST1

116

P53990
LGSSELKKIKQDIYC

IQCB1

41

Q15051
LEAKCALKYLIGELV

KIF4A

861

O95239
LEAKCALKYLIGELV

KIF4B

861

Q2VIQ3
KLADLKNSCEYKLTG

EMILIN2

336

Q9BXX0
EIKKCGREGITLNKY

GRAMD2A

56

Q8IUY3
AEEVCRQKKGKSLYK

FMN2

1691

Q9NZ56
ELKAFYELICKIKGN

DIRAS3

126

O95661
EKLIKNYIIKCLEVS

OLAH

246

Q9NV23
LKKESLRAKCQGYAL

COL6A6

2101

A6NMZ7
LEICQKSLTGYLEKK

DNAH5

1696

Q8TE73
KLALLKQIQEAYGKC

ING4

61

Q9UNL4
ESKCLVIEKNGKLRY

HSPA14

86

Q0VDF9
KDLTYSVICKKCGLD

EPHA6

361

Q9UF33
DQKKKQLEDLSYCRE

NUP88

596

Q99567
LQCYEGKSSKDILKR

RTTN

1846

Q86VV8
LLELYCEDKQSKIKE

UTP20

2566

O75691
IYKLKEQLLDCEGED

RGPD4

131

Q7Z3J3
IEGYRKNEESLKKCV

TACC3

736

Q9Y6A5
LKELKGLSCLVSYQD

STAT2

276

P52630
KECAARGEDYEKVKL

SYF2

86

O95926
SKYCEDLFGDLLLKQ

PLCB4

421

Q15147
ETKLQKAGTYLCLLE

TRGC1

21

P0CF51
ETKLQKAGTYLCLLE

TRGC2

21

P03986
SCKDLALYENLFKKE

SPATA5L1

731

Q9BVQ7
AYLLENGICIAKKKT

RIMS4

156

Q9H426
KNKKLLTDGYACEVR

NKRF

231

O15226
YFGKEKLKEIKLLVC

CMAS

266

Q8NFW8
KVYSCLNNKLEKLLG

RIF1

876

Q5UIP0
LLLYGADIESKNKCG

POTEB

221

A0A0A6YYL3
KKEKLEALYGQLVSC

FSD2

281

A1L4K1
QVKTCKAKIELLGSY

ACP1

106

P24666
KCGLELETDENRIYK

SHLD2

701

Q86V20
CLKVVELYLNEKKRG

SIN3B

906

O75182
RLKYALTGDEVKKIC

RPS4Y1

51

P22090
RLKYALTGDEVKKIC

RPS4Y2

51

Q8TD47
TKIEEGGYKRLCLKE

NUDT12

291

Q9BQG2
RLKYALTGDEVKKIC

RPS4X

51

P62701
NLVLFDKATYDKLCK

RPS25

46

P62851
DKKLKTLEELCDTEY

SMCR8

316

Q8TEV9
ESVLCKEIKEYLIKL

TASOR

1241

Q9UK61
KEIKEYLIKLGNTEC

TASOR

1246

Q9UK61
YADLCTNKDLKKAIL

ACSL6

621

Q9UKU0
KDLLNCEQKVSDGKY

COL24A1

1546

Q17RW2
NKLLAEAKEYVIKAC

SUPT6H

731

Q7KZ85
AKLKVGQYLNCIVEK

PDCD11

231

Q14690
LACEKILKKSYEAAL

THEMIS

411

Q8N1K5
KLLSLKKEVYEIELC

ZNF383

86

Q8NA42
KNLNEKDYELLCLDG

TF

571

P02787
LKKKGYRCTTEAEQD

RELL1

81

Q8IUW5
EAAAKGKYEICKLLL

TNKS

756

O95271
IDLIYCGRKLKDDQT

UBL7

61

Q96S82
LKCEDLKVGQYICKD

TM2D1

46

Q9BX74
LQCIKQYADKIKSGI

TTC3

821

P53804
DKYLSDKDFQCLIKL

PXK

186

Q7Z7A4
VKPLDELYEKKANCI

SCN8A

1031

Q9UQD0
LNEYKALKKDDEQLC

SMC6

371

Q96SB8
LDKKANLLKCEYCGK

PHC1

791

P78364
LKKCKEAGLLNYLLE

PHF11

221

Q9UIL8
VCKKLVGYLDRNLEK

PSAP

411

P07602
LGLCLGYEDEKKNEK

VSTM1

11

Q6UX27
KTEAKQEYLLKDCDL

XPA

141

P23025
IAEAYATKGLCLEKL

TTC7B

141

Q86TV6
KDQVYALKLKGISIC

XPO7

821

Q9UIA9
KYKNAGVIELEACIK

TRAPPC9

336

Q96Q05
ITKAEKLEIAKGYCT

PPIP5K2

766

O43314
AVSELKKDLDIICKY

TEX15

2131

Q9BXT5
KKDLDIICKYNEAVN

TEX15

2136

Q9BXT5
LAEKYRECLSNKEKI

THOC5

201

Q13769
DKLLCDVFKKGDVYL

SLC27A6

446

Q9Y2P4
ASDEKVLIEAYKKCL

UBR2

556

Q8IWV8
YIKETEKDCLNLDKN

PTPRC

426

P08575
EKDCLNLDKNLIKYD

PTPRC

431

P08575
LSLVEIYKQRCAKKG

TRRAP

3591

Q9Y4A5
LNRVKKKEYVELCDA

USP11

416

P51784
DEKYTGLKKQLRDLC

USP6

741

P35125
VLLYKQDFTKKLGLC

ZMYM3

661

Q14202
AEKEKALLTKCAYLQ

TBC1D2

486

Q9BYX2
YKAGDKDCLAKESVI

TMEM145

86

Q8NBT3
EEKLAALCKKYAELL

TXLNA

186

P40222
EYCLKVLKKEGENFK

TTC9

151

Q92623
CVSLKKEYENLKEAR

TRAIP

201

Q9BWF2
DSLDKEIKFLKCLYD

KRT74

266

Q7RTS7
GQLLCKGDYEKEKDL

LMX1B

161

O60663
NYTKEKIKIVEGICL

LRP4

1801

O75096
KDYKCLVEKLTNLEG

MYO5A

941

Q9Y4I1
EYKLDREFLKGCKLS

NEB

5581

P20929