Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesscilium assembly

FSIP2 TCTN3 CFAP73 FBF1 TTC21B PKHD1 IFT122 WDR54 CPLANE1 DNAH1

2.15e-054448910GO:0060271
GeneOntologyBiologicalProcesscilium organization

FSIP2 TCTN3 CFAP73 FBF1 TTC21B PKHD1 IFT122 WDR54 CPLANE1 DNAH1

3.89e-054768910GO:0044782
GeneOntologyCellularComponentcilium

FSIP2 RSPH10B2 TCTN3 SLC26A8 DRD2 PPP3CC CFAP73 FBF1 TTC21B PKHD1 TOMM20 IFT122 WDR54 CPLANE1 DNAH1

7.22e-068989115GO:0005929
GeneOntologyCellularComponent9+2 motile cilium

FSIP2 RSPH10B2 SLC26A8 DRD2 PPP3CC TOMM20 DNAH1

8.16e-05238917GO:0097729
GeneOntologyCellularComponentmotile cilium

FSIP2 RSPH10B2 SLC26A8 DRD2 PPP3CC CFAP73 TOMM20 DNAH1

1.60e-04355918GO:0031514
GeneOntologyCellularComponentsperm flagellum

FSIP2 SLC26A8 DRD2 PPP3CC TOMM20 DNAH1

3.47e-04214916GO:0036126
GeneOntologyCellularComponentintegrin complex

ITGA8 ITGAM ITGB6

3.61e-0432913GO:0008305
GeneOntologyCellularComponentintraciliary transport particle A

TTC21B IFT122

5.16e-048912GO:0030991
GeneOntologyCellularComponentapical part of cell

MLC1 SLC19A1 PKHD1 ITGA8 GNAS TLR9 SLC39A10 ABCA7 ABCC6

1.10e-03592919GO:0045177
GeneOntologyCellularComponentapical plasma membrane

MLC1 SLC19A1 PKHD1 GNAS TLR9 SLC39A10 ABCA7 ABCC6

1.28e-03487918GO:0016324
Domain-

MFHAS1 NTRK2 LRRC1 LRRC69 PIDD1 ZYG11B TLR9 NRROS RABGGTA NLRC4 NLRP3

4.54e-0732191113.80.10.10
DomainL_dom-like

MFHAS1 NTRK2 LRRC1 LRRC69 PIDD1 ZYG11B TLR9 NRROS RABGGTA NLRC4 NLRP3

5.61e-073289111IPR032675
DomainLeu-rich_rpt

MFHAS1 NTRK2 LRRC1 LRRC69 PIDD1 ZYG11B TLR9 NRROS RABGGTA NLRP3

8.01e-072719110IPR001611
DomainLRR

MFHAS1 LRRC1 LRRC69 PIDD1 ZYG11B TLR9 NRROS RABGGTA

6.20e-06201918PS51450
DomainLRR_1

MFHAS1 NTRK2 LRRC1 LRRC69 PIDD1 TLR9 NRROS RABGGTA

1.16e-05219918PF00560
DomainLRR_8

MFHAS1 NTRK2 LRRC1 LRRC69 PIDD1 TLR9 NRROS

2.02e-05171917PF13855
DomainTPR

TRAPPC12 CTR9 TTC21B TTC27 FKBPL KDM6A

3.98e-05129916SM00028
DomainTPR_repeat

TRAPPC12 CTR9 TTC21B TTC27 FKBPL KDM6A

4.73e-05133916IPR019734
Domain-

TRAPPC12 CTR9 TTC21B TTC27 FKBPL IFT122 KDM6A

6.84e-052079171.25.40.10
DomainTPR-contain_dom

TRAPPC12 CTR9 TTC21B TTC27 FKBPL KDM6A

9.23e-05150916IPR013026
DomainTPR-like_helical_dom

TRAPPC12 CTR9 TTC21B TTC27 FKBPL IFT122 KDM6A

1.43e-04233917IPR011990
DomainTPR_REGION

TRAPPC12 CTR9 TTC21B TTC27 FKBPL KDM6A

1.56e-04165916PS50293
DomainTPR

TRAPPC12 CTR9 TTC21B TTC27 FKBPL KDM6A

1.56e-04165916PS50005
DomainPentatricopeptide_repeat

PTCD1 POLRMT GNAS

1.85e-0423913IPR002885
DomainLeu-rich_rpt_typical-subtyp

MFHAS1 LRRC1 LRRC69 PIDD1 TLR9 NRROS

2.28e-04177916IPR003591
DomainLRR_TYP

MFHAS1 LRRC1 LRRC69 PIDD1 TLR9 NRROS

2.28e-04177916SM00369
DomainIntegrin_dom

ITGA8 ITGAM ITGB6

2.38e-0425913IPR032695
DomainIntegrin_alpha

ITGA8 ITGAM

1.25e-0311912PF00357
DomainTPR_8

CTR9 TTC21B KDM6A

2.20e-0353913PF13181
DomainLRR_6

TLR9 NRROS NLRP3

2.44e-0355913PF13516
DomainIntegrin_alpha_C_CS

ITGA8 ITGAM

2.70e-0316912IPR018184
DomainIntegrin_alpha-2

ITGA8 ITGAM

3.41e-0318912IPR013649
DomainIntegrin_alpha2

ITGA8 ITGAM

3.41e-0318912PF08441
DomainIntegrin_alpha

ITGA8 ITGAM

3.41e-0318912IPR000413
DomainINTEGRIN_ALPHA

ITGA8 ITGAM

3.41e-0318912PS00242
DomainInt_alpha_beta-p

ITGA8 ITGAM

3.80e-0319912IPR013519
DomainInt_alpha

ITGA8 ITGAM

3.80e-0319912SM00191
Pubmed

The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response.

TLR9 NLRC4 NLRP3

1.90e-07594318288107
Pubmed

Congenital Hepatic Fibrosis Overview ─ RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY

TCTN3 TTC21B PKHD1 IFT122 CPLANE1

3.04e-075294520301743
Pubmed

Acetaminophen-induced hepatotoxicity in mice is dependent on Tlr9 and the Nalp3 inflammasome.

TLR9 NLRC4 NLRP3

3.80e-07694319164858
Pubmed

The T helper type 2 response to cysteine proteases requires dendritic cell-basophil cooperation via ROS-mediated signaling.

TLR9 NLRC4 NLRP3

4.13e-061294320495560
Pubmed

Variants in NLRP3 and NLRC4 inflammasome associate with susceptibility and severity of multiple sclerosis.

NLRC4 NLRP3

7.23e-06294230658261
Pubmed

Inflammasome Genetic Variants, Macrophage Function, and Clinical Outcomes in Cystic Fibrosis.

NLRC4 NLRP3

7.23e-06294233848452
Pubmed

Common variants in the NLRP3 region contribute to Crohn's disease susceptibility.

OR2B11 NLRP3

7.23e-06294219098911
Pubmed

The Salmonella pathogenicity island-2 subverts human NLRP3 and NLRC4 inflammasome responses.

NLRC4 NLRP3

7.23e-06294230368901
Pubmed

NLRC4 inflammasome activation is NLRP3- and phosphorylation-independent during infection and does not protect from melanoma.

NLRC4 NLRP3

7.23e-06294232342103
Pubmed

Integrin αM activation and upregulation on esophageal eosinophils and periostin-mediated eosinophil survival in eosinophilic esophagitis.

POSTN ITGAM

7.23e-06294229424023
Pubmed

Actions of the NLRP3 and NLRC4 inflammasomes overlap in bone resorption.

NLRC4 NLRP3

7.23e-06294234383985
Pubmed

NAIP/NLRC4 inflammasome participates in macrophage responses to Trypanosoma cruzi by a mechanism that relies on cathepsin-dependent caspase-1 cleavage.

NLRC4 NLRP3

7.23e-06294238124741
Pubmed

Flagellin/NLRC4 Pathway Rescues NLRP3-Inflammasome Defect in Dendritic Cells From HIV-Infected Patients: Perspective for New Adjuvant in Immunocompromised Individuals.

NLRC4 NLRP3

7.23e-06294231244842
Pubmed

TLR9 and the NLRP3 inflammasome link acinar cell death with inflammation in acute pancreatitis.

TLR9 NLRP3

7.23e-06294221439959
Pubmed

Novel mutations of TCTN3/LTBP2 with cellular function changes in congenital heart disease associated with polydactyly.

TCTN3 LTBP2

7.23e-06294233098376
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

ATP13A4 ZNF536 HIVEP1 TRAPPC12 FBF1 AGK NRROS KDM6A ABCC6 USP47

9.12e-06638941031182584
Pubmed

Cord factor and peptidoglycan recapitulate the Th17-promoting adjuvant activity of mycobacteria through mincle/CARD9 signaling and the inflammasome.

TLR9 NLRC4 NLRP3

1.04e-051694323630357
Pubmed

Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity.

TLR9 NLRC4 NLRP3

1.26e-051794322297845
Pubmed

Involvement of the AIM2, NLRC4, and NLRP3 inflammasomes in caspase-1 activation by Listeria monocytogenes.

NLRC4 NLRP3

2.16e-05394220490635
Pubmed

Dock3 stimulates axonal outgrowth via GSK-3β-mediated microtubule assembly.

DOCK3 NTRK2

2.16e-05394222219288
Pubmed

Nuclear factor E2-related factor-2 (Nrf2) is required for NLRP3 and AIM2 inflammasome activation.

NLRC4 NLRP3

2.16e-05394224798340
Pubmed

Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4.

NLRC4 NLRP3

2.16e-05394221118981
Pubmed

Actin polymerization as a key innate immune effector mechanism to control Salmonella infection.

NLRC4 NLRP3

2.16e-05394225422455
Pubmed

A novel role for the NLRC4 inflammasome in mucosal defenses against the fungal pathogen Candida albicans.

NLRC4 NLRP3

2.16e-05394222174673
Pubmed

The vaccine adjuvant alum inhibits IL-12 by promoting PI3 kinase signaling while chitosan does not inhibit IL-12 and enhances Th1 and Th17 responses.

TLR9 NLRP3

2.16e-05394222777876
Pubmed

Associations of common polymorphisms in the thymidylate synthase, reduced folate carrier and 5-aminoimidazole-4-carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase genes with folate and homocysteine levels and venous thrombosis risk.

SLC19A1 ATIC

2.16e-05394217439323
Pubmed

Polyglutamation of methotrexate with common polymorphisms in reduced folate carrier, aminoimidazole carboxamide ribonucleotide transformylase, and thymidylate synthase are associated with methotrexate effects in rheumatoid arthritis.

SLC19A1 ATIC

2.16e-05394215457444
Pubmed

Impact of NTRK2, DRD2 and ACE polymorphisms on prolactin levels in antipsychotic-treated patients with first-episode psychosis.

DRD2 NTRK2

2.16e-05394229767567
Pubmed

Artificial Loading of ASC Specks with Cytosolic Antigens.

NLRC4 NLRP3

2.16e-05394226258904
Pubmed

Microglia-neuron interactions promote chronic itch via the NLRP3-IL-1β-GRPR axis.

GRPR NLRP3

2.16e-05394236876522
Pubmed

β-arrestin1 is critical for the full activation of NLRP3 and NLRC4 inflammasomes.

NLRC4 NLRP3

2.16e-05394225582856
Pubmed

Aberrant expression of NLRP3, NLRC4 and NLRP6 inflammasomes in patients with primary immune thrombocytopenia.

NLRC4 NLRP3

2.16e-05394230802690
Pubmed

Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration.

NLRC4 NLRP3

2.16e-05394217599094
Pubmed

TLR agonists regulate alloresponses and uncover a critical role for donor APCs in allogeneic bone marrow rejection.

TLR9 ITGAM

2.16e-05394218614760
Pubmed

Mast cells mediate neutrophil recruitment and vascular leakage through the NLRP3 inflammasome in histamine-independent urticaria.

NLRC4 NLRP3

2.16e-05394219364881
Pubmed

Latent Upregulation of Nlrp3, Nlrc4 and Aim2 Differentiates between Asymptomatic and Symptomatic Trichomonas vaginalis Infection.

NLRC4 NLRP3

2.16e-05394233866944
Pubmed

Toll-Like Receptor 9 Is Involved in NLRP3 Inflammasome Activation and IL-1β Production Through Monosodium Urate-Induced Mitochondrial DNA.

TLR9 NLRP3

2.16e-05394232700178
Pubmed

G Protein signaling modulator-3 inhibits the inflammasome activity of NLRP3.

NLRC4 NLRP3

2.16e-05394225271165
Pubmed

Evaluation of NLRC4, NLRP1, and NLRP3, as Components of Inflammasomes, in Chronic Hepatitis B Virus-Infected Patients.

NLRC4 NLRP3

2.16e-05394227750030
Pubmed

USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation.

NLRP3 USP47

2.16e-05394230206189
Pubmed

Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella.

NLRC4 NLRP3

2.16e-05394220603313
Pubmed

Polymorphisms in folate, pyrimidine, and purine metabolism are associated with efficacy and toxicity of methotrexate in psoriasis.

SLC19A1 ATIC

2.16e-05394217410198
Pubmed

Cutting edge: Candida albicans hyphae formation triggers activation of the Nlrp3 inflammasome.

NLRC4 NLRP3

2.16e-05394219684085
Pubmed

NFκB and NLRP3/NLRC4 inflammasomes regulate differentiation, activation and functional properties of monocytes in response to distinct SARS-CoV-2 proteins.

NLRC4 NLRP3

2.16e-05394238453949
Pubmed

Cutting edge: Necrosis activates the NLRP3 inflammasome.

NLRC4 NLRP3

2.16e-05394219596994
Pubmed

Association of Inflammasome Components in Background Liver with Poor Prognosis After Curatively-resected Hepatocellular Carcinoma.

NLRC4 NLRP3

2.16e-05394228011505
Pubmed

Pharmacogenetic and metabolite measurements are associated with clinical status in patients with rheumatoid arthritis treated with methotrexate: results of a multicentred cross sectional observational study.

SLC19A1 ATIC

2.16e-05394215677700
Pubmed

The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1.

NLRC4 NLRP3

2.16e-05394219362023
Pubmed

A role for mitochondria in NLRP3 inflammasome activation.

NLRC4 NLRP3

2.16e-05394221124315
Pubmed

Sall1 balances self-renewal and differentiation of renal progenitor cells.

POSTN BMP5 ZNF536 ITGA8

3.37e-056794424550112
Pubmed

Chlamydia evasion of neutrophil host defense results in NLRP3 dependent myeloid-mediated sterile inflammation through the purinergic P2X7 receptor.

TLR9 NLRC4 NLRP3

3.71e-052494334526512
Pubmed

Bypassing pathogen-induced inflammasome activation for the regulation of interleukin-1beta production by the fungal pathogen Candida albicans.

NLRC4 NLRP3

4.32e-05494219222370
Pubmed

Mycobacterial hypersensitivity pneumonitis requires TLR9-MyD88 in lung CD11b+ CD11c+ cells.

TLR9 ITGAM

4.32e-05494221273385
Pubmed

Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome.

NLRC4 NLRP3

4.32e-05494218070936
Pubmed

NLRP3 recruitment by NLRC4 during Salmonella infection.

NLRC4 NLRP3

4.32e-05494227139490
Pubmed

Increased expression of tenascin-C-binding epithelial integrins in human bullous keratopathy corneas.

ITGA8 ITGB6

4.32e-05494211668187
Pubmed

Multiple Nod-like receptors activate caspase 1 during Listeria monocytogenes infection.

NLRC4 NLRP3

4.32e-05494218490757
Pubmed

Critical roles of ASC inflammasomes in caspase-1 activation and host innate resistance to Streptococcus pneumoniae infection.

NLRC4 NLRP3

4.32e-05494221957143
Pubmed

Involvement of the NLRP3 inflammasome in innate and humoral adaptive immune responses to fungal beta-glucan.

NLRC4 NLRP3

4.32e-05494220007575
Pubmed

Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome.

NLRC4 NLRP3

4.32e-05494220333626
Pubmed

NLRP3 inflammasome mediates interleukin-1β production in immune cells in response to Acinetobacter baumannii and contributes to pulmonary inflammation in mice.

NLRC4 NLRP3

4.32e-05494228032341
Pubmed

Dock3 induces axonal outgrowth by stimulating membrane recruitment of the WAVE complex.

DOCK3 NTRK2

4.32e-05494220368433
Pubmed

NLRC4 regulates caspase-1 and IL-1beta production in a CD11blowLy6Glow population of cells required for resistance to Pseudomonas aeruginosa keratitis.

ITGAM NLRC4

4.32e-05494228961278
Pubmed

Cutting edge: alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome.

NLRC4 NLRP3

4.32e-05494218768827
Pubmed

Inhibition of inflammasome activation by Coxiella burnetii type IV secretion system effector IcaA.

NLRC4 NLRP3

4.32e-05494226687278
Pubmed

Differential regulation of caspase-1 activation via NLRP3/NLRC4 inflammasomes mediated by aerolysin and type III secretion system during Aeromonas veronii infection.

NLRC4 NLRP3

4.32e-05494221037094
Pubmed

AIM2 and NLRC4 inflammasomes contribute with ASC to acute brain injury independently of NLRP3.

NLRC4 NLRP3

4.32e-05494225775556
Pubmed

ABCB1 C3435T polymorphism influences methotrexate sensitivity in rheumatoid arthritis patients.

SLC19A1 ATIC

4.32e-05494217181924
Pubmed

The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer.

NLRC4 NLRP3

4.32e-05494220385749
Pubmed

Inflammatory role of ASC in antigen-induced arthritis is independent of caspase-1, NALP-3, and IPAF.

NLRC4 NLRP3

4.32e-05494219717512
Pubmed

Asc and Ipaf Inflammasomes direct distinct pathways for caspase-1 activation in response to Legionella pneumophila.

NLRC4 NLRP3

4.32e-05494219237518
Pubmed

Interleukin-18 diagnostically distinguishes and pathogenically promotes human and murine macrophage activation syndrome.

NLRC4 NLRP3

4.32e-05494229326099
Pubmed

Granuloma formation and host defense in chronic Mycobacterium tuberculosis infection requires PYCARD/ASC but not NLRP3 or caspase-1.

NLRC4 NLRP3

4.32e-05494220808838
Pubmed

The Nlrp3 inflammasome is critical for aluminium hydroxide-mediated IL-1beta secretion but dispensable for adjuvant activity.

NLRC4 NLRP3

4.32e-05494218624356
Pubmed

Radiation causes tissue damage by dysregulating inflammasome-gasdermin D signaling in both host and transplanted cells.

NLRC4 NLRP3

4.32e-05494232760056
Pubmed

TLR2 and caspase-1 signaling are critical for bacterial containment but not clearance during craniotomy-associated biofilm infection.

TLR9 NLRP3

4.32e-05494232290861
Pubmed

Cutting edge: proteolytic inactivation of poly(ADP-ribose) polymerase 1 by the Nlrp3 and Nlrc4 inflammasomes.

NLRC4 NLRP3

4.32e-05494220713892
Pubmed

Cytotoxins of the human pathogen Aeromonas hydrophila trigger, via the NLRP3 inflammasome, caspase-1 activation in macrophages.

NLRC4 NLRP3

4.32e-05494220722078
Pubmed

Dock3 regulates BDNF-TrkB signaling for neurite outgrowth by forming a ternary complex with Elmo and RhoG.

DOCK3 NTRK2

4.32e-05494222734669
Pubmed

Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants.

NLRC4 NLRP3

4.32e-05494218496530
Pubmed

Candidate genes for panic disorder: insight from human and mouse genetic studies.

DRD2 NTRK2

4.32e-05494217543035
Pubmed

TLR agonists stimulate Nlrp3-dependent IL-1β production independently of the purinergic P2X7 receptor in dendritic cells and in vivo.

NLRC4 NLRP3

4.32e-05494223225887
Pubmed

Disruption of glycolytic flux is a signal for inflammasome signaling and pyroptotic cell death.

NLRC4 NLRP3

4.32e-05494227011353
Pubmed

Perlecan regulates pericyte dynamics in the maintenance and repair of the blood-brain barrier.

ITGA8 ITGAM ITGB6

5.34e-052794331541017
Pubmed

Targeted peptidecentric proteomics reveals caspase-7 as a substrate of the caspase-1 inflammasomes.

NLRC4 NLRP3

7.19e-05594218667412
Pubmed

Critical role for Ipaf in Pseudomonas aeruginosa-induced caspase-1 activation.

NLRC4 NLRP3

7.19e-05594217935074
Pubmed

Activation of the Nlrp3 inflammasome by Streptococcus pyogenes requires streptolysin O and NF-kappa B activation but proceeds independently of TLR signaling and P2X7 receptor.

NLRC4 NLRP3

7.19e-05594219812205
Pubmed

Structural insights into the human D1 and D2 dopamine receptor signaling complexes.

DRD2 GNAS

7.19e-05594233571431
Pubmed

DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs.

NLRC4 NLRP3

7.19e-05594234860583
Pubmed

Obesity-associated NLRC4 inflammasome activation drives breast cancer progression.

NLRC4 NLRP3

7.19e-05594227708283
Pubmed

Toll-like receptor and inflammasome signals converge to amplify the innate bactericidal capacity of T helper 1 cells.

NLRC4 NLRP3

7.19e-05594224508233
Pubmed

Cryopyrin activates the inflammasome in response to toxins and ATP.

NLRC4 NLRP3

7.19e-05594216407890
Pubmed

Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome.

NLRC4 NLRP3

7.19e-05594219918053
Pubmed

Sickle red cells as danger signals on proinflammatory gene expression, leukotriene B4 and interleukin-1 beta production in peripheral blood mononuclear cell.

TLR9 NLRP3

7.19e-05594227045344
Pubmed

Chromosomal localization, embryonic expression, and imprinting tests for Bmp7 on distal mouse chromosome 2.

BMP5 GNAS

7.19e-0559427490098
Pubmed

Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis.

NLRC4 NLRP3

7.19e-05594216717117
Pubmed

Cytosolic flagellin-induced lysosomal pathway regulates inflammasome-dependent and -independent macrophage responses.

NLRC4 NLRP3

7.19e-05594223942123
Pubmed

TLR9 Regulates the NF-κB-NLRP3-IL-1β Pathway Negatively in Salmonella-Induced NKG2D-Mediated Intestinal Inflammation.

TLR9 NLRP3

7.19e-05594228576980
Pubmed

Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1α and IL-1β.

NLRC4 NLRP3

7.19e-05594220974980
Pubmed

Salmonella enterica Serovar Typhimurium Induces NAIP/NLRC4- and NLRP3/ASC-Independent, Caspase-4-Dependent Inflammasome Activation in Human Intestinal Epithelial Cells.

NLRC4 NLRP3

7.19e-05594235678562
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

TRAPPC12 CTR9 TTC21B TTC27 FKBPL KDM6A

2.20e-06115606769
GeneFamilyCD molecules|Integrin alpha subunits

ITGA8 ITGAM

1.60e-03186021160
GeneFamilyAbhydrolase domain containing

ABHD16B ABHD1

2.40e-03226024
GeneFamilyIntraflagellar transport proteins|Tetratricopeptide repeat domain containing

TTC21B IFT122

2.85e-0324602615
GeneFamilyNLR family

NLRC4 NLRP3

3.09e-0325602666
ToppCellLPS-IL1RA-Endothelial-Mes-Like-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCED1B ZFHX4 ANKAR HAUS5 FKBPL PIDD1 ATIC

2.53e-0814594790ca38c02325c5c637c32efdef634b54cc3cd105
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CFAP73 FBF1 AGK IFT122 WDR54 DNAH1

1.54e-061689469a8709d34865cfa668d8f3335dc34fc86fc32482
ToppCellPCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DOCK3 ATP13A4 FRY PKHD1 ITGB6 ABCC6

2.95e-061889460d86044bc340e3efb90d0022dd299873639d831c
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_basal-Dividing_Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

POSTN MGAT2 CTR9 FBF1 FKBPL ABHD1

3.64e-061959465812b1615676f3b77eb4769216b98b360c417c0d
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-Like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK3 RTKN2 ZFHX4 PKHD1 GRPR

3.68e-06110945c80d1c3df75648e2c8f6832279c2acca63d76681
ToppCellLPS_only-Epithelial_airway-airway_epithelial-Ciliated|LPS_only / Treatment groups by lineage, cell group, cell type

TCTN3 ARMC3 CFAP73 IFT122 NAGS DNAH1

3.97e-061989466d90b541fde357fbb40f8f7d4e8628a48b679718
ToppCell10x5'v1-week_14-16-Mesenchymal_myocytic-stroma-muscle_stem_cell|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

RGMA POSTN BMP5 ZFHX4 NTRK2 LTBP2

4.09e-061999466200618e029063486719479c41eaf31798bd13cf
ToppCellTCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-2|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

AP2A2 TOMM20 IFT122 LTBP2 ITGAM

2.87e-05168945c70bf73bb800e4722cedc35bbc17ea3113d1012d
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RTKN2 ATP13A4 LRRC1 PKHD1 ITGB6

3.68e-051779459af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCellControl-Epithelial_alveolar-AT_1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RTKN2 ATP13A4 LRRC1 PKHD1 ITGB6

3.78e-05178945aa7d43c655df493f1330a5001efaa484e4a19f69
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_2|356C / Donor, Lineage, Cell class and subclass (all cells)

RTKN2 ANKAR FBF1 FKBPL NRROS

3.78e-051789458b939659f713eea50a1a6e28b571f680ca0b4c12
ToppCellControl-Epithelial_alveolar-AT_1-AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RTKN2 ATP13A4 LRRC1 PKHD1 ITGB6

3.78e-051789451817bc520f3d23da8c0fa09bba50ae703a820cb1
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RTKN2 ATP13A4 LRRC1 PKHD1 ITGB6

3.89e-0517994504ce3673e46606f63d9c87bcba3a64c96817d812
ToppCell368C-Endothelial_cells-Endothelial-E|368C / Donor, Lineage, Cell class and subclass (all cells)

POSTN ADCY4 FRY NTRK2 PCDH12

3.99e-051809458ab16a0b9053bffc07b569a4f9e71749f56dde7e
ToppCell368C-Endothelial_cells-Endothelial-E-|368C / Donor, Lineage, Cell class and subclass (all cells)

POSTN ADCY4 FRY NTRK2 PCDH12

3.99e-05180945394cd465b88429b70eebb2957480dffcbc51cfe7
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RTKN2 ATP13A4 LRRC1 PKHD1 ITGB6

4.10e-05181945b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellCOVID-19-lung-AT1|COVID-19 / Disease (COVID-19 only), tissue and cell type

RTKN2 ATP13A4 SLC19A1 LRRC1 ITGB6

4.32e-051839457b1a385ed54f93bfe85bf0c162e42d05d516b45c
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK3 HIVEP1 MFHAS1 KDM6A ITGB6

4.43e-05184945d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D175|Adult / Lineage, Cell type, age group and donor

RTKN2 ATP13A4 LRRC1 CPLANE1 ITGB6

4.54e-0518594532b4e68e551d435a732f253f6ad83408c759a642
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 ATP13A4 FRY PKHD1 ABCC6

5.03e-051899457659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK3 MFHAS1 NTRK2 PKHD1 ITGB6

5.29e-051919452fa1b9e76a0ed2d2f0de74349e266cf4a5f51aad
ToppCelldroplet-Kidney-nan-3m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POSTN ZNF536 NTRK2 ARHGAP20 TAT

5.29e-05191945d1205aab0937f2becfcd239610e9b78fb8a0c886
ToppCell10x5'v1-week_12-13-Mesenchymal_adipo-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

RGMA BMP5 NTRK2 ITGA8 LTBP2

5.56e-05193945cf2461af78f65616ce40d552ee9452295e3895ed
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

POSTN BMP5 ZNF536 ITGA8 LTBP2

5.56e-05193945e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCell10x5'v1-week_12-13-Mesenchymal_adipo|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

RGMA BMP5 NTRK2 ITGA8 LTBP2

5.56e-051939456ef9007c9d18fb775d08fb20cdf954a28d54d7eb
ToppCell10x5'v1-week_12-13-Mesenchymal_adipo-stroma-adipo-CAR|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

RGMA BMP5 NTRK2 ITGA8 LTBP2

5.56e-05193945e4ea7ce011a80b81b841c907719aa532bed39d2e
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RGMA POSTN ARMC3 MLC1 GNAS

5.69e-0519494568d15917ae222cba0ad9e716d29eebb6c5f00f69
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 ATP13A4 FRY ARMC3 PKHD1

5.69e-051949456b286992d4bb56013c0ea5a7601d3476d806175a
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo-stroma-osteoblast_precursor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

RGMA POSTN BMP5 ZFHX4 ITGA8

5.98e-0519694557df2a57b35be9851ac0b1e5731baa53052511f0
ToppCell10x3'2.3-week_17-19-Mesenchymal_adipo|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

POSTN BMP5 ZFHX4 NTRK2 LTBP2

6.12e-051979455afddde4e2b5cd55abe11e9b9efae02dbdc3da3a
ToppCell10x3'2.3-week_17-19-Mesenchymal_adipo-stroma-adipo-CAR|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

POSTN BMP5 ZFHX4 NTRK2 LTBP2

6.12e-051979451baffd087ca194a7355fefbb3bf67befb14fe2de
ToppCell10x3'2.3-week_17-19-Mesenchymal_adipo-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

POSTN BMP5 ZFHX4 NTRK2 LTBP2

6.12e-05197945b9745e382baa2725dfcae060701fb53f6c8a31fa
ToppCellBiopsy_IPF-Epithelial-AT1|Biopsy_IPF / Sample group, Lineage and Cell type

RTKN2 ATP13A4 SLC19A1 ABCA7 ITGB6

6.27e-0519894575bdecbe111fededf6082b11de18b84ca308ef6d
ToppCell10x5'v1-week_14-16-Mesenchymal_adipo-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

POSTN BMP5 ZFHX4 NTRK2 LTBP2

6.42e-051999459b2262edbdec89166d895ab97527e0ee5f9b6010
ToppCell10x5'v1-week_14-16-Mesenchymal_adipo|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

POSTN BMP5 ZFHX4 NTRK2 LTBP2

6.42e-05199945251b3643dcd8f4645b17101bd716e66f12a20e88
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RGMA POSTN MLC1 NTRK2 GNAS

6.42e-051999456723287924750a2247a07ab6e561066a97b09771
ToppCell10x5'v1-week_14-16-Mesenchymal_adipo-stroma-adipo-CAR|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

POSTN BMP5 ZFHX4 NTRK2 LTBP2

6.42e-05199945117f4f43b6c06dda553799b1063e827bce697370
ToppCellPND01-03-samps-Mesenchymal-Myofibroblast-MyoFB-3|PND01-03-samps / Age Group, Lineage, Cell class and subclass

PLXNA3 MFHAS1 SLC19A1 LTBP2

1.92e-041359445b13ff740d9f7d96274aebb6b389a80f6004adc7
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TLR9 ITGAM NLRC4 NLRP3

2.72e-041489447c7c87b57aa16f8b91698489df39ace5a3a53df8
ToppCellFetal_29-31_weeks-Mesenchymal-chondrocyte-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

POSTN BMP5 ITGA8 LTBP2

2.94e-0415194432d35906f4b2bd46b173e87f2dec972eb5da87b3
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_4|368C / Donor, Lineage, Cell class and subclass (all cells)

PCED1B RTKN2 MFHAS1 C16orf96

2.94e-041519445d64655b6b09cc0a6d44629a31048b787a0916c5
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_memory_T_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RTKN2 MFHAS1 NTRK2 USP47

3.09e-0415394464d0f37d7af9b76234f683379e3689771f71fe70
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal--glomerular_mesenchymal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RGMA CFAP73 ITGA8 GNAS

3.17e-041549443211f003f4d1735c7cab9b6cc68af3e0bbfba35e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RGMA CFAP73 ITGA8 GNAS

3.17e-04154944c0fe767fc9ab45b2dfa71171f2a673a4a8decbaf
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RGMA CFAP73 ITGA8 GNAS

3.17e-041549444c2a7590791c2255b15dab82c3622f71f9ffd949
ToppCellE16.5-samps-Mesenchymal-Myofibroblast-Migrating_MyoFibroblast|E16.5-samps / Age Group, Lineage, Cell class and subclass

TCTN3 ENDOD1 ZNF536 LTBP2

3.25e-041559441882fa5fd25f77d6e3ac47b613f6fb3c67d8e50c
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RTKN2 LRRC1 PKHD1 ITGB6

3.41e-041579449665a1375cfd8e9b8781c852686591226c0e0d9a
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MFHAS1 FBF1 PKHD1 ITGB6

3.41e-041579444766f7d545bf2d775390589460677519cb92f4d5
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte|Children_(3_yrs) / Lineage, Cell type, age group and donor

ZNF536 ZFHX4 ITGA8 LTBP2

3.41e-04157944f147e24f2ece82e1c54750868954d09b3c461804
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Grp_(Neuron.Slc17a6.Grp)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

ESPNL PKHD1 NAGS

3.51e-0465943b7bc23af54d6d2f7afd584f4df42c24d7c49e344
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Grp_(Neuron.Slc17a6.Grp)|Hippocampus / BrainAtlas - Mouse McCarroll V32

ESPNL PKHD1 NAGS

3.51e-04659433b3630253f5713c4a688c74c4ea0f98c1fe42594
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ATP13A4 PKHD1 ITGB6 ABCC6

3.58e-04159944e6ff9d2bce62bf9ea173af80b688eeb40fa4ea4c
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-AT1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RTKN2 LRRC1 PKHD1 ITGB6

3.75e-041619441e17a993126e1f2a25ee7dfbb95a74ccb2a26791
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3|Striatum / BrainAtlas - Mouse McCarroll V32

BMP5 SLC19A1 ITGA8 PCDH12

4.02e-04164944e24b06a14565f7798ac50c2fe3f34d4547b9000e
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARMC3 CFAP73 IFT122 ASB14

4.02e-041649449e16e52f5a634585f26021bcce9b5d5992ff6db0
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 ATP13A4 ARMC3 PKHD1

4.11e-041659440c714e852f912b5749de4cb0895406673979b2e6
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 ATP13A4 ARMC3 PKHD1

4.11e-0416594482530f96aaefe28a13bad0474bbad043f127a86c
ToppCellEndothelial-B-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

ENDOD1 ADCY4 ZFHX4 PCDH12

4.31e-041679446a03d16165e0b003092c39972928981abd4a75aa
ToppCell15-Distal-Epithelial-Multiciliated_precursor|Distal / Age, Tissue, Lineage and Cell class

RSPH10B2 ABHD16B ARMC3 CFAP73

4.31e-04167944442ea71a581ed5a547a214132b9f1b0243fd0895
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l15|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AGK LTBP2 PCDH12 ARHGAP20

4.31e-0416794455c3c68af269fcf40f2b080ae4489523609ad388
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGMA LRRC1 LTBP2 ITGB6

4.31e-04167944cf6206c506715cd846799c62cf7c06e3fa99f7af
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Microglia/Mac|Myeloid_cells / Location, Cell class and cell subclass

SLC26A8 ABCA7 ITGB6 DNAH1

4.50e-04169944dba8f5599aa21feef5b7fdfed2e3ab54748d80f7
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARMC3 C16orf96 CPLANE1 DNAH1

4.50e-04169944fba841664939c771881ba97f14ef1df6635c04ff
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGMA LRRC1 LTBP2 ITGB6

4.50e-0416994430141f76e9bfc2b4586429857c72dbc85ba65cc9
ToppCellLV-13._Vascular_Smooth_Muscle|LV / Chamber and Cluster_Paper

PCED1B FRY NTRK2 ITGA8

4.71e-04171944e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Monocytes|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MLC1 ITGAM NLRC4 NLRP3

4.81e-04172944cf46810dd1072b6f2171e5d9530351ddc79a055b
ToppCellAdult-Endothelial-endothelial_cell_of_bronchial_vessel|Adult / Lineage, Cell type, age group and donor

POSTN ADCY4 LRRC69 PCDH12

4.81e-04172944ad4ffdb3fc0c560a9cbaa2bc048476cbc43e8fd6
ToppCell-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

BMP5 MLC1 ITGA8 LTBP2

4.92e-0417394488be9182fbb1bc83531cd41e59ea57c112a21d54
ToppCell5'-Adult-Appendix-Mesenchymal-myocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RGMA POSTN BMP5 ITGA8

4.92e-04173944f8e3dded726bb3a6c24bfedf8c6732bb46262308
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

RTKN2 ATP13A4 SLC19A1 ITGB6

4.92e-04173944b799c06a6a5754668e789f70c0c8bc1508568575
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

POSTN BMP5 ZNF536 ITGA8

5.03e-04174944f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLXNA3 POSTN RTKN2 LTBP2

5.03e-04174944a7ade7372e83edd4e3983e77f8417b51f0b47340
ToppCelldroplet-Bladder-Unstain-18m-Hematologic-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARMC3 NRROS ITGAM NLRP3

5.03e-04174944773329bb91b97578df138446cf62101dd0dad758
ToppCell10x3'2.3-week_17-19-Lymphocytic_T-T_NK-Treg|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PCED1B FSIP2 RTKN2 PORCN

5.03e-041749447ca39c9ecd609e5ade30dac1a948a4a4fff1b3b2
ToppCellControl-Epithelial_cells-AT1|Control / group, cell type (main and fine annotations)

RTKN2 ATP13A4 SLC19A1 LRRC1

5.03e-04174944548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Endothelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY4 ZNF536 PCDH12 ITGAM

5.13e-04175944c36b4526970db9ccfbe2c70b00961fab9f13b133
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY4 ZNF536 PCDH12 ITGAM

5.13e-04175944c1e082538f31b5c98ac63f71dcca4a1211a14708
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Endothelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY4 ZNF536 PCDH12 ITGAM

5.13e-041759442f9b5bdf8a62e8e99d1c4f677a8e5525bfd3b4ce
ToppCellCiliated_cells-A-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

RSPH10B2 ZNF536 ARMC3 CFAP73

5.25e-041769441c364155f46b9a7c995bdc2cc2333c437cd90f5b
ToppCellTCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Endometrioid-2|TCGA-Endometrium / Sample_Type by Project: Shred V9

TRAPPC12 POLRMT ABCA7 RABGGTA

5.25e-04176944179b1778e8f6c4cd777cec971960211e7ba5d84a
ToppCellP15-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

POSTN ZNF536 FBF1 WDR54

5.25e-04176944792f414f5092aba14260b8e16378e793a822498e
ToppCelldroplet-Lung-nan-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGMA POSTN SLC19A1 LTBP2

5.36e-0417794465709bd546cb1ec6aa2ddd8b2adb46e174eb9a9a
ToppCelldroplet-Lung-nan-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGMA POSTN SLC19A1 LTBP2

5.36e-041779448684d47a547e2a06496f15e8da0200ecddc431e0
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARMC3 WDR97 CFAP73 DNAH1

5.47e-041789443b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCellPND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RGMA RTKN2 ATP13A4 ITGB6

5.47e-04178944a3af5d9c55858e36be0498081029ecb0acaeb3d3
ToppCelldroplet-Heart-4Chambers-18m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY4 ESPNL IFT122 PCDH12

5.47e-0417894493ce73f8bcec63ebf86fabb546f88400e8f06465
ToppCellPND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RGMA RTKN2 ATP13A4 ITGB6

5.47e-04178944b3b88989bd602cfb55bb5c47731deb99288a8952
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGMA ITGA8 ARHGAP20 DNAH1

5.59e-04179944b44e2d53b82c3c141bfc6539054b19708200a0d9
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

PCDH12 ITGAM NLRC4 NLRP3

5.59e-04179944cc079ba015326dccde955c5eafa3e4a2e40de192
ToppCellCOVID-19-Epithelial_cells-AT1|COVID-19 / group, cell type (main and fine annotations)

RTKN2 ATP13A4 SLC19A1 ITGB6

5.59e-04179944a0b33bd69ffdfd5d38d80207fb40058a490aa19e
ToppCellStriatum-Endothelial-MURAL|Striatum / BrainAtlas - Mouse McCarroll V32

BMP5 SLC19A1 ITGA8 PCDH12

5.59e-041799443d58babf44e47462c3d4129dd2e94a2339fd7ce0
ToppCell10x3'2.3-week_12-13-Myeloid_macrophage-stroma-erythroid_macrophage|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

POSTN HIVEP1 NTRK2 ARHGAP20

5.59e-04179944c17ae394b855f01f8ca1765c416fd8b34a96e60b
ToppCellAT1_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

RTKN2 ATP13A4 SLC19A1 LRRC1

5.59e-041799441603117b52623663458a977c94bf7f9f6c1114b8
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

POSTN ZNF536 ZFHX4 LTBP2

5.59e-0417994402c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCellhuman_hepatoblastoma-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

DOCK3 FRY ZFHX4 ARMC3

5.59e-0417994414fc8ccb6b215063d747643f47d780d2b237eb67
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)|Striatum / BrainAtlas - Mouse McCarroll V32

BMP5 SLC19A1 ITGA8 PCDH12

5.59e-0417994499167ac678cae5c35b1d4f4a81b32000437c00c2
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADCY4 LRRC1 PIDD1 PCDH12

5.71e-0418094440d4838a0ccb10d5e49266bc8a0037d27b75ccc2
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c11-MKI67-FOS|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ENDOD1 ARMC3 CTR9 IFT122

5.83e-041819446873c1138b28c130637d06b64981ad11c262e85f
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FSIP2 POSTN LTBP2 GNAS

5.83e-0418194440df0afcb6848202da54670e84f22d7c3a515d01
ToppCellCOVID-19-Epithelial-Ionocytes|Epithelial / Condition, Lineage and Cell class

DOCK3 POSTN FAM222A LTBP2

5.83e-041819444a8d4f2709c1b25f908867f1b2fae1d2d0abf1d4
DiseaseFamilial aplasia of the vermis

TCTN3 TTC21B CPLANE1

3.22e-0520923cv:C0431399
DiseaseCryopyrin-Associated Periodic Syndromes

NLRC4 NLRP3

5.75e-054922C2316212
DiseaseChronic Infantile Neurological, Cutaneous, and Articular Syndrome

NLRC4 NLRP3

5.75e-054922C0409818
DiseaseFamilial Cold Autoinflammatory Syndrome 1

NLRC4 NLRP3

5.75e-054922C4551895
DiseaseFamilial cold urticaria

NLRC4 NLRP3

5.75e-054922C0343068
DiseaseFamilial cold autoinflammatory syndrome

NLRC4 NLRP3

5.75e-054922cv:C0343068
DiseaseMuckle-Wells Syndrome

NLRC4 NLRP3

9.56e-055922C0268390
DiseaseHereditary Autoinflammatory Diseases

NLRC4 NLRP3

2.00e-047922C0751422
DiseaseOROFACIODIGITAL SYNDROME VI

TCTN3 CPLANE1

2.00e-047922C2745997
DiseasePituitary Adenoma

DRD2 GNAS

3.41e-049922C0032000
DiseaseCrohn's disease of large bowel

TYK2 TLR9 NLRP3

3.54e-0444923C0156147
DiseaseIIeocolitis

TYK2 TLR9 NLRP3

3.54e-0444923C0949272
Diseaseschizophrenia (is_marker_for)

DRD2 PPP3CC NTRK2

3.54e-0444923DOID:5419 (is_marker_for)
DiseaseCrohn's disease of the ileum

TYK2 TLR9 NLRP3

3.54e-0444923C0267380
DiseaseRegional enteritis

TYK2 TLR9 NLRP3

3.54e-0444923C0678202
Diseaseabdominal aortic aneurysm (is_marker_for)

POSTN ITGAM

4.26e-0410922DOID:7693 (is_marker_for)
DiseasePolydactyly

TCTN3 TTC21B PORCN CPLANE1

5.01e-04117924C0152427
DiseaseCrohn Disease

TYK2 TLR9 NLRP3

5.17e-0450923C0010346
Diseaselupus nephritis (is_implicated_in)

TLR9 ITGAM

1.42e-0318922DOID:0080162 (is_implicated_in)
DiseaseTachycardia

DRD2 GNAS

1.42e-0318922C0039231
DiseaseTachyarrhythmia

DRD2 GNAS

1.42e-0318922C0080203
Diseaseunipolar depression, bipolar disorder

ATP13A4 ZNF536 DRD2 NTRK2

1.46e-03156924EFO_0003761, MONDO_0004985
Diseaseprion disease

ATRIP MFHAS1

1.59e-0319922EFO_0004720
DiseaseSchizophrenia

RTKN2 SLC26A8 DRD2 PPP3CC MLC1 NTRK2 ITGA8 GNAS ITGAM

1.75e-03883929C0036341
Diseasetestosterone measurement

TYK2 DOCK3 BMP5 ZNF536 ZFHX4 TRAPPC12 DLGAP4 TTC27 FKBPL C16orf96 NLRC4

2.05e-0312759211EFO_0004908
Diseasealcohol use disorder measurement, alcohol dependence

DRD2 PKHD1

2.54e-0324922EFO_0009458, MONDO_0007079

Protein segments in the cluster

PeptideGeneStartEntry
LVGFIQCQLIEGQLQ

TTC21B

361

Q7Z4L5
SLLYQLNQQCQAPGA

FAM222A

201

Q5U5X8
AACQEAQVFGNQLIP

AGK

41

Q53H12
PQRINVCGQLNLVCF

ATP13A4

471

Q4VNC1
VAIPVFANGNIQCLQ

DUS1L

201

Q6P1R4
LPQLAANAVLFLCGN

ADCY4

171

Q8NFM4
LENATFLLLNGCNPN

ASB14

131

A6NK59
DFFNNQGIPQLIQLL

ARMC3

351

Q5W041
LNLFQLVCQHQGQPP

CFAP73

256

A6NFT4
KFQQFRGLCEQNLNP

DLGAP4

856

Q9Y2H0
QGLICNVNNTCFPQL

ABCA7

71

Q8IZY2
SQAQCLLQQLRELPG

ABHD16B

81

Q9H3Z7
SEPNLLVRACNQLGQ

AP2A2

321

O94973
LLPFLQNLCSQVNHL

PAAT

331

Q9H8K7
QAGAAFQVLQLPQAL

PCDH12

61

Q9NPG4
GACDGLQNLILLNLN

LRRC69

101

Q6ZNQ3
QNQICEGNGIAPLVR

ANKAR

1026

Q7Z5J8
ENIRPNACQIKGNLF

RSPH10B2

526

B2RC85
CVKFLVQRAQLPGNQ

ESPNL

51

Q6ZVH7
LLNNLGNVCINCRQP

IFT122

1066

Q9HBG6
QAIDLCLAVLANPGQ

TAT

146

P17735
QLTLNGLLQALQSPC

NLRC4

151

Q9NPP4
LPNLDLLNLFQTFCQ

GPAA1

246

O43292
NQLIAGVNFCPVLQV

MGAT2

161

Q10469
GLQALPAQFSCLQRL

MFHAS1

261

Q9Y4C4
RALCQAGQPQAINQL

ASB12

281

Q8WXK4
YLQAQLCNLPQGSLQ

KDM6A

396

O15550
NLLPQFGSQEIIQNC

FSIP2

6091

Q5CZC0
KLLPFNPQLFQNNCG

ENDOD1

256

O94919
QINGNFCGLVLNQPL

PLXNA3

381

P51805
TPANLLAKGCQLNFI

ITGB6

61

P18564
QLLQPNAGGFLCRQA

MINDY4B

286

A8MYZ0
ENLENLFQCLGQVLP

PCED1B

141

Q96HM7
LVQRDIQAFLNQCGA

NAGS

101

Q8N159
ACTLRAQFLQNLLLP

HAUS5

191

O94927
IFHIQTLGPLQCQPN

ITGA8

856

P53708
QENLPRCGALENLVN

LRRC1

426

Q9BTT6
PNLVSQLCGVFLQNE

MAS1L

41

P35410
LTVQLPFCGRQVLNN

OR2B11

166

Q5JQS5
CPNDNQTAQLLALIL

PPP4R3C

501

Q6ZMV5
RQEFFQQLLQGCLLP

PORCN

6

Q9H237
QQLLQGCLLPTAQQG

PORCN

11

Q9H237
GNLRSQLFPQLCQQL

DNAH1

1456

Q9P2D7
QLFPQLCQQLSDLVA

DNAH1

1461

Q9P2D7
LAAQVQLQCSPAELQ

FBF1

566

Q8TES7
ANLAACQLLLGQPQL

FKBPL

256

Q9UIM3
PNFQRALFQQVVGAC

DOCK3

1806

Q8IZD9
ANIAIPQCGVLNFKA

C16orf96

11

A6NNT2
QIFQEKLQCVLGQPA

CPLANE1

1066

Q9H799
KQFNTQLLCCQPGLI

GRPR

331

P30550
NNIPALLGKACISFN

CTR9

161

Q6PD62
INPQNNLGLQLCAET

BMP5

261

P22003
LNTVNGQCANPLLEL

LTBP2

556

Q14767
ISCPLLFGLNNADQN

DRD2

166

P14416
LCLLPQLIQHFENPN

FRY

2146

Q5TBA9
PLVQFFIGLHCQALQ

ATRIP

421

Q8WXE1
CPVGQFILQNLGLLF

SLC39A10

796

Q9ULF5
LVLQLFQAKGCPQLG

POLRMT

716

O00411
NLAFNNLPCIVDFGL

NRROS

211

Q86YC3
GCQQLLHLCVQQPLQ

PIDD1

46

Q9HB75
LIVDAFLQQLPNCVN

UPF2

566

Q9HAU5
NPQCNLQKLGLVNSG

NLRP3

881

Q96P20
QLFGISLPNICENDN

ARHGAP20

361

Q9P2F6
LRLAGLPTQQDCNIQ

RTKN2

11

Q8IZC4
CDFLNLQLQQPLQLA

BMT2

201

Q1RMZ1
LLCFVLPATNAAQQA

ABCC6

141

O95255
CNAFQNANILILIAG

SLC26A8

746

Q96RN1
VLLNLQGNPLCQAVG

RABGGTA

536

Q92696
QGNPLCQAVGILEQL

RABGGTA

541

Q92696
FDQPAQRGCSQLLLQ

GNAS

166

Q5JWF2
LAGQNQLLLLCPDFR

PKHD1

4011

P08F94
GLCFLFGSNLRQQPQ

ITGAM

121

P11215
LRGCPLNQQIDFQAF

RGMA

316

Q96B86
NSLLFNQPLTAGLCQ

ABHD1

246

Q96SE0
NQPLTAGLCQLVERN

ABHD1

251

Q96SE0
LANLQIPNCGLPSAN

NTRK2

186

Q16620
LPLAALLNQQFLCVH

PPP3CC

181

P48454
LPVRNNDQALGLTQC

SUN5

51

Q8TC36
QLCQQQLGLDPNFLR

ZFHX4

2066

Q86UP3
NLPVQLAASACVFNL

ZYG11B

376

Q9C0D3
LANCQGQPSALRQVN

nan

61

Q96MF0
PRNAVANNNAAVCLL

TRAPPC12

651

Q8WVT3
NCISQAVNGSQFLPL

TLR9

506

Q9NR96
LQLNGAPQALAFCSN

WDR97

726

A6NE52
LNFNLQQLCGPKCRD

UBE4B

1121

O95155
LGLQCLPSDGVQNVN

SLC19A1

576

P41440
LCNADNAQIPLANGL

USP47

971

Q96K76
LNGAPGFINLCDALN

ATIC

231

P31939
NLQLLQNCLAVLNGD

SNX6

391

Q9UNH7
QQAPLAACTLALQAN

ZNF536

231

O15090
GRDQGPNVCALQQIL

POSTN

36

Q15063
LVPNLQTFCNLAIGC

PTCD1

551

O75127
QANAPLLAGNTCQNV

TCTN3

306

Q6NUS6
IILGICTNFQKNNPV

TTC27

346

Q6P3X3
AALNIQVGNLCQFLP

SMC5

166

Q8IY18
QVGNLCQFLPQDKVG

SMC5

171

Q8IY18
EGLQFQNALGCNPSL

HIVEP1

1056

P15822
AIAVCGQPQQLLQVL

TOMM20

96

Q15388
NLLPFVGLNNLGNTC

USP1

76

O94782
ALCNNLSVLQLPARN

WDR54

16

Q9H977
GLAQLLLFAQQICEG

TYK2

996

P29597
CKLVLNPSAININFN

MLC1

131

Q15049