Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesscellular response to high light intensity

SLC24A4 AKT2

1.93e-052912GO:0071486
GeneOntologyBiologicalProcesspositive regulation of phosphatidylcholine metabolic process

ACSL3 CAPN2

5.76e-053912GO:0150173
GeneOntologyBiologicalProcesspositive regulation of phosphatidylcholine biosynthetic process

ACSL3 CAPN2

5.76e-053912GO:2001247
GeneOntologyBiologicalProcesscellular response to light intensity

SLC24A4 AKT2

1.15e-044912GO:0071484
GeneOntologyBiologicalProcessresponse to high light intensity

SLC24A4 AKT2

1.15e-044912GO:0009644
MousePhenoataxia

RHBDF1 MATR3 DAB1 WDR81 IREB2 AFF1 MYO15A ATP2B2

6.46e-05266728MP:0001393
MousePhenoabnormal Purkinje cell morphology

MATR3 DAB1 PI4K2A WDR81 IREB2 AFF1 ATP2B2

8.39e-05204727MP:0000877
MousePhenoabnormal cerebellar Purkinje cell layer

MATR3 DAB1 PI4K2A WDR81 IREB2 AFF1 ATP2B2

1.34e-04220727MP:0000875
MousePhenoembryonic lethality prior to organogenesis, complete penetrance

SEC24D RBBP6 MATR3 SPTB CAPN2 RGPD1 SMARCC1 DGCR8 ARID1A CDH1 MRPS22 GSPT1 TGS1

1.38e-047727213MP:0014259
MousePhenoembryonic lethality prior to tooth bud stage, complete penetrance

SEC24D RBBP6 MATR3 SPTB CAPN2 RGPD1 SMARCC1 DGCR8 ARID1A CDH1 MRPS22 GSPT1 TGS1

1.51e-047797213MP:0014257
DomainIsochorismatase

ISOC2 ISOC1

2.35e-052912PF00857
Domain-

ISOC2 ISOC1

2.35e-0529123.40.50.850
DomainIsochorismatase-like

ISOC2 ISOC1

2.35e-052912IPR000868
DomainFumarylacetoacetase_C-rel

FAHD2B FAHD2A

1.40e-044912IPR011234
DomainFAA_hydrolase

FAHD2B FAHD2A

1.40e-044912PF01557
Domain-

FAHD2B FAHD2A

1.40e-0449123.90.850.10
DomainFERM_M

PTPN3 MYO15A KRIT1

1.46e-0346913PF00373
DomainFERM_central

PTPN3 MYO15A KRIT1

1.75e-0349913IPR019748
DomainFERM_domain

PTPN3 MYO15A KRIT1

1.75e-0349913IPR000299
DomainFERM_1

PTPN3 MYO15A KRIT1

1.86e-0350913PS00660
DomainFERM_2

PTPN3 MYO15A KRIT1

1.86e-0350913PS00661
DomainFERM_3

PTPN3 MYO15A KRIT1

1.86e-0350913PS50057
DomainBand_41_domain

PTPN3 MYO15A KRIT1

1.86e-0350913IPR019749
DomainB41

PTPN3 MYO15A KRIT1

1.86e-0350913SM00295
DomainPI3/4_kinase_cat_dom

PIK3C2G PI4K2A

3.41e-0318912IPR000403
DomainPI3_PI4_kinase

PIK3C2G PI4K2A

3.41e-0318912PF00454
DomainPI3_4_KINASE_3

PIK3C2G PI4K2A

3.41e-0318912PS50290
DomainPI3_4_KINASE_1

PIK3C2G PI4K2A

3.41e-0318912PS00915
DomainPI3_4_KINASE_2

PIK3C2G PI4K2A

3.41e-0318912PS00916
DomainHEAT_REPEAT

SCYL2 GCN1 AP3D1

4.84e-0370913PS50077
DomainTyr_Pase_AS

PTPN3 PTPN12 DUSP10

5.44e-0373913IPR016130
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

ACSL3 TGM3 EXOSC10 PTPN12 DDX52 AHNAK MATR3 CAPN2 RBM7 SMARCC1 ISOC1 AFDN MYO1B ACAA2 ALDH1B1 ARID1A GCN1 AP3D1 RPL7A GSPT1

4.77e-101353942029467282
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

SCYL2 EXOSC10 ALMS1 RBBP6 AHNAK SH3D19 MATR3 TPX2 SMARCC1 AFDN ARID1A GCN1 EMSY

3.08e-09549941338280479
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

EXOSC10 SLC15A1 AHNAK MATR3 TPX2 SMARCC1 GON4L MYO1B RPL7A

1.57e-0823494936243803
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

EXOSC10 FYTTD1 KHDRBS3 RBBP6 MATR3 RBM7 SMARCC1 MYO1B SPOCK2 ARID1A GPC6 GCN1 AP3D1 MRPS22 SDAD1 RPL7A

3.26e-081082941638697112
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

ACSL3 EXOSC10 DDX52 MATR3 CAPN2 TPX2 PI4K2A SMARCC1 AFDN MYO1B ACAA2 SDAD1

3.89e-08560941235241646
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

ACSL3 MED6 EXOSC10 ZNF609 FYTTD1 RBBP6 DDX52 AHNAK MATR3 TPX2 RBM7 SMARCC1 CDYL ARID1A TET3 EMSY RPL7A

6.36e-081294941730804502
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

EXOSC10 FYTTD1 TTLL3 RHBDF1 DDX52 MATR3 DZIP3 SMARCC1 AFF1 SPOCK2 GALNT7 CDH1 BICC1 TGS1 EHD3

2.15e-071084941511544199
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

SCYL2 EXOSC10 PTPN12 ALMS1 RBBP6 AHNAK SH3D19 MATR3 TPX2 MYO1B GCN1 AP3D1 EMSY RPL7A

2.19e-07934941433916271
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

MED6 ZNF609 FYTTD1 RBBP6 DDX52 MATR3 SMARCC1 AFF1 MYO1B ALDH1B1 ARID1A CDH1 GCN1 MRPS22 RPL7A GSPT1

2.24e-071247941627684187
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

EXOSC10 FYTTD1 KHDRBS3 DDX52 AHNAK MATR3 TPX2 DAB1 RBM7 SMARCC1 ISOC1 IREB2 MYO1B GCN1 AP3D1 SDAD1

7.88e-071371941636244648
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

EXOSC10 FYTTD1 RBBP6 DDX52 MATR3 TPX2 DGCR8 GCN1 AP3D1 MRPS22 SDAD1 RPL7A

9.97e-07759941235915203
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

ACSL3 KHDRBS3 DDX52 AHNAK MATR3 RGPD1 SMARCC1 MAP7D2 MYO1B ALDH1B1 ARID1A CDH1 ATP2B2 AP3D1 RPL7A GSPT1

1.52e-061442941635575683
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

ACSL3 TGM3 EXOSC10 DDX52 AHNAK SMARCC1 AFDN MYO1B ARID1A GCN1 RPL7A

1.58e-06653941122586326
Pubmed

ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.

MATR3 TPX2 SMARCC1 GON4L CDYL ARID1A

3.47e-0615094628242625
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

SCYL2 PTPN3 ZNF609 SH3D19 PI4K2A WDR81 IREB2 AFDN CDH1 MRPS22 GSPT1

3.98e-06719941135337019
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

ACSL3 ZNF609 RBBP6 AHNAK MATR3 RBM7 SMARCC1 AFDN RMND1 GALNT7 GPC6 AP3D1 SDAD1 RPL7A

4.30e-061203941429180619
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

TGM3 PTPN3 EXOSC10 RBBP6 DDX52 AHNAK MATR3 TPX2 ISOC1 MYO1B CDH1 MRPS22 SDAD1 RPL7A

7.09e-061257941436526897
Pubmed

DGCR8 Acts as an Adaptor for the Exosome Complex to Degrade Double-Stranded Structured RNAs.

EXOSC10 DGCR8

7.23e-06294226687677
Pubmed

ARID1A regulates E-cadherin expression in colorectal cancer cells: a promising candidate therapeutic target.

ARID1A CDH1

7.23e-06294234424445
Pubmed

Differential expression of murine CGI-105 gene in 3T3-L1 cells by adrenocorticotropic hormones.

FAHD2B FAHD2A

7.23e-06294215774318
Pubmed

PI3K-C2γ is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling.

PIK3C2G AKT2

7.23e-06294226100075
Pubmed

Regulation of epithelial wound closure and intercellular adhesion by interaction of AF6 with actin cytoskeleton.

AFDN CDH1

7.23e-06294216882694
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

ACSL3 SLC41A3 RBBP6 MATR3 TPX2 PI4K2A RBM7 SMARCC1 AFF1 AFDN EMSY

7.98e-06774941115302935
Pubmed

CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.

CFAP47 EXOSC10 ALMS1 AHNAK MATR3 TPX2 SMARCC1 GCN1 RPL7A

8.00e-0649494926831064
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

MED6 EXOSC10 ZNF609 TPX2 SMARCC1 ARID1A EMSY

8.62e-0626894733640491
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

EXOSC10 ZNF609 RBBP6 AHNAK MATR3 TPX2 RBM7 SMARCC1 AFDN DGCR8 ARID1A EMSY

1.03e-05954941236373674
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

MED6 FYTTD1 RHBDF1 RBBP6 DDX52 CRACDL TPX2 RBM7 GON4L AFDN CDYL DGCR8 MRPS22 SDAD1 EMSY

1.14e-051497941531527615
Pubmed

A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export.

ACSL3 PI4K2A MYO1B ACAA2 GALNT7 ARID1A GCN1 GSPT1

1.16e-0539294833144569
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

SCYL2 ZNF609 CAPN2 RBM7 ARID1A GCN1 MRPS22

1.20e-0528294723667531
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

EXOSC10 ZNF609 PTPN12 PDPR GCN1 AP3D1 MRPS22 GSPT1

1.25e-0539694826687479
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

ACSL3 PTPN3 EXOSC10 PTPN12 MATR3 CAPN2 AFDN DUSP10 RMND1 GCN1 MRPS22 RPL7A

1.26e-05974941228675297
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

EXOSC10 FYTTD1 DDX52 AHNAK MATR3 TPX2 SMARCC1 MYO1B DGCR8 ALDH1B1 SDAD1 RPL7A

1.47e-05989941236424410
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

ACSL3 TGM3 PTPN12 PDPR AHNAK CAPN2 SMARCC1 AFDN ARID1A GCN1 MRPS22 EMSY RPL7A GSPT1

1.81e-051367941432687490
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

SCYL2 EXOSC10 RBBP6 DDX52 MATR3 TPX2 RBM7 MYO1B MRPS22 SDAD1 RPL7A

1.84e-05847941135850772
Pubmed

Oct4 links multiple epigenetic pathways to the pluripotency network.

AHNAK MATR3 SMARCC1 AFDN ARID1A GCN1

1.95e-0520394622083510
Pubmed

A universal metabolite repair enzyme removes a strong inhibitor of the TCA cycle.

FAHD2B FAHD2A

2.16e-05394238287013
Pubmed

ARID1A downregulation promotes cell proliferation and migration of colon cancer via VIM activation and CDH1 suppression.

ARID1A CDH1

2.16e-05394236420658
Pubmed

Afadin regulates actomyosin organization through αE-catenin at adherens junctions.

AFDN CDH1

2.16e-05394232227204
Pubmed

Pioneer factor ASCL1 cooperates with the mSWI/SNF complex at distal regulatory elements to regulate human neural differentiation.

SMARCC1 ARID1A

2.16e-05394236931659
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

SCYL2 AHNAK SH3D19 AFDN MYO1B CDH1 GCN1 RPL7A GSPT1

2.31e-0556594925468996
Pubmed

RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.

EXOSC10 FYTTD1 RBBP6 DDX52 MATR3 DGCR8 GCN1 MRPS22 SDAD1 RPL7A

2.37e-05713941029802200
Pubmed

Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.

ACSL3 AHNAK RGPD1 MAP7D2 AFDN GCN1

2.69e-0521594635973513
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

SCYL2 EXOSC10 FYTTD1 AHNAK TPX2 RBM7 ARID1A GCN1 GSPT1

2.91e-0558294920467437
Pubmed

Human transcription factor protein interaction networks.

ZNF609 ALMS1 RBBP6 DDX52 MATR3 TPX2 RGPD1 SMARCC1 GON4L MYO1B ARID1A MRPS22 SDAD1 EMSY

2.95e-051429941435140242
Pubmed

Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells.

MATR3 RGPD1 SMARCC1 ARID1A MRPS22

3.40e-0513594531077711
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

ACSL3 TGM3 SEC24D PDPR CRACDL AHNAK MATR3 SMARCC1 ACAA2 GALNT7 ARID1A AP3D1 RPL7A TMPRSS11B

3.49e-051451941430550785
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

PTPN12 ALMS1 RBBP6 AHNAK TPX2 SMARCC1 ARID1A GCN1

4.16e-0546994827634302
Pubmed

Mesothelium of the murine allantois exhibits distinct regional properties.

AFDN CDH1

4.32e-05494221284019
Pubmed

Deregulation of ARID1A, CDH1, cMET and PIK3CA and target-related microRNA expression in gastric cancer.

ARID1A CDH1

4.32e-05494226334097
Pubmed

Role of nectin in formation of E-cadherin-based adherens junctions in keratinocytes: analysis with the N-cadherin dominant negative mutant.

AFDN CDH1

4.32e-05494212686612
Pubmed

Two related ARID family proteins are alternative subunits of human SWI/SNF complexes.

SMARCC1 ARID1A

4.32e-05494215170388
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

ACSL3 SEC24D PTPN12 RBBP6 AHNAK TPX2 PI4K2A TRMT11 MYO1B CDYL GALNT7 AP3D1 RPL7A

4.64e-051297941333545068
Pubmed

Interaction network of human early embryonic transcription factors.

ZNF609 ALMS1 RGPD1 SMARCC1 ARID1A CDH1 EMSY

4.85e-0535194738297188
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

PTPN3 SEC24D EXOSC10 AHNAK AFDN DGCR8 GCN1 AP3D1 RPL7A DMXL1

4.88e-05777941035844135
Pubmed

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.

ZNF609 TPX2 RGPD1 ARID1A EMSY

4.95e-0514694523892456
Pubmed

Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.

ACSL3 EXOSC10 DDX52 MATR3 SMARCC1 ALDH1B1 AP3D1 RPL7A

5.34e-0548694830940648
Pubmed

Nuclear lamina genetic variants, including a truncated LAP2, in twins and siblings with nonalcoholic fatty liver disease.

ACSL3 AHNAK MATR3 MYO1B GCN1 RPL7A

5.45e-0524494628902428
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

GLRX5 RBBP6 DDX52 AHNAK MATR3 SMARCC1 CDYL GCN1 AP3D1 MRPS22 EMSY RPL7A GSPT1

5.46e-051318941330463901
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

ACSL3 ISOC2 CAPN2 RGPD1 ISOC1 MAP7D2 AFDN AKT2 TMEM35A ALDH1B1 GCN1 RPL7A

5.80e-051139941236417873
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

FYTTD1 RGPD1 SMARCC1 ARID1A GCN1 GSPT1 KRIT1

6.75e-0537094722922362
Pubmed

Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms.

ACSL3 GSTT1 PTPN12 AHNAK CDH1 MRPS22

7.11e-0525694624189400
Pubmed

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.

GLRX5 RBBP6 SPTB IREB2 MYO1B ARHGAP28 MYO15A GPC6 MRPS22 BICC1

7.18e-05814941023251661
Pubmed

Akt2 interacts with Snail1 in the E-cadherin promoter.

AKT2 CDH1

7.19e-05594222158034
Pubmed

p300/CREB binding protein-related protein p270 is a component of mammalian SWI/SNF complexes.

SMARCC1 ARID1A

7.19e-0559429584200
Pubmed

NKX6.1 functions as a metastatic suppressor through epigenetic regulation of the epithelial-mesenchymal transition.

SMARCC1 CDH1

7.19e-05594226257059
Pubmed

The HSA domain of BRG1 mediates critical interactions required for glucocorticoid receptor-dependent transcriptional activation in vivo.

SMARCC1 ARID1A

7.19e-05594218086889
Pubmed

p62/SQSTM1 Fuels Melanoma Progression by Opposing mRNA Decay of a Selective Set of Pro-metastatic Factors.

ACSL3 AHNAK TPX2 MYO1B MRPS22

7.41e-0515994530581152
Pubmed

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.

ZNF609 RBBP6 MATR3 RGPD1 AFDN MYO1B ARID1A RPL7A GSPT1

8.12e-0566594930457570
Pubmed

UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex.

SCYL2 AHNAK MATR3 AFDN MRPS22 RPL7A

8.96e-0526794633417871
Pubmed

Insights into the ubiquitin-proteasome system of human embryonic stem cells.

MED6 AHNAK DZIP3 CDH1 AP3D1 RPL7A

9.33e-0526994629511261
Pubmed

Homologous Transcription Factors DUX4 and DUX4c Associate with Cytoplasmic Proteins during Muscle Differentiation.

TGM3 AHNAK CAPN2 PI4K2A AP3D1 RPL7A

9.72e-0527194626816005
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

SCYL2 INTS6L PTPN12 SPTB RBM7 GON4L IREB2 MYO1B AKT2 BIN3 HERC2P3 DMXL1

1.07e-041215941215146197
Pubmed

Testing for association between MeCP2 and the brahma-associated SWI/SNF chromatin-remodeling complex.

SMARCC1 ARID1A

1.08e-04694216940996
Pubmed

Afadin: A key molecule essential for structural organization of cell-cell junctions of polarized epithelia during embryogenesis.

AFDN CDH1

1.08e-04694210477764
Pubmed

The cell adhesion gene PVRL3 is associated with congenital ocular defects.

AFDN CDH1

1.08e-04694221769484
Pubmed

Binding between the junctional proteins afadin and PLEKHA7 and implication in the formation of adherens junction in epithelial cells.

AFDN CDH1

1.08e-04694223990464
Pubmed

Variations in the composition of mammalian SWI/SNF chromatin remodelling complexes.

SMARCC1 ARID1A

1.08e-04694219650111
Pubmed

Genomics and hearing impairment.

MYO15A ATP2B2

1.08e-0469429927480
Pubmed

Absence of the tight junctional protein AF-6 disrupts epithelial cell-cell junctions and cell polarity during mouse development.

AFDN CDH1

1.08e-04694210469590
Pubmed

The p270 (ARID1A/SMARCF1) subunit of mammalian SWI/SNF-related complexes is essential for normal cell cycle arrest.

SMARCC1 ARID1A

1.08e-04694216230384
Pubmed

Characterization and significance of adhesion and junction-related proteins in mouse ovarian follicles.

AFDN CDH1

1.08e-04694222321830
Pubmed

Expression patterns of nectins and afadin during epithelial remodeling in the mouse embryo.

AFDN CDH1

1.08e-04694215108322
Pubmed

ATG5 is required for B cell polarization and presentation of particulate antigens.

MED6 FYTTD1 RBBP6 MATR3 RGPD1 SMARCC1 GCN1 MRPS22 SDAD1

1.21e-0470194930196744
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

ACSL3 PTPN3 ZNF609 PTPN12 PDPR AHNAK MYO1B DUSP10 ARID1A GCN1 SDAD1

1.26e-041049941127880917
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

SCYL2 AHNAK SH3D19 ISOC1 AFDN MYO1B GCN1 AP3D1 RPL7A

1.30e-0470894939231216
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

FAHD2B TTLL3 SLC41A3 CRACDL GYS2 FAHD2A AKT2 ALDH1B1 MYO15A GPC6 CDH1 ATP2B2

1.31e-041242941230973865
Pubmed

The functional interactome landscape of the human histone deacetylase family.

ZNF609 TPX2 SMARCC1 CDYL GCN1 EMSY

1.38e-0428994623752268
Pubmed

Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.

ACSL3 FYTTD1 DDX52 MATR3 RBM7 GCN1 AP3D1 MRPS22 RPL7A

1.39e-0471494928302793
Pubmed

Rap1 regulates lumen continuity via Afadin in renal epithelia.

AFDN CDH1

1.50e-04794237276970
Pubmed

Reversible disruption of mSWI/SNF (BAF) complexes by the SS18-SSX oncogenic fusion in synovial sarcoma.

SMARCC1 ARID1A

1.50e-04794223540691
Pubmed

Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.

EXOSC10 FYTTD1 KHDRBS3 RBBP6 DDX52 MATR3 RBM7 MRPS22 RPL7A

1.65e-0473194929298432
Pubmed

Variability in Streptavidin-Sepharose Matrix Quality Can Significantly Affect Proximity-Dependent Biotinylation (BioID) Data.

ACSL3 GLRX5 FYTTD1 TRMT11 ACAA2 ALDH1B1 MRPS22

1.91e-0443894732628020
Pubmed

Downregulation of ten-eleven translocation-2 triggers epithelial differentiation during organogenesis.

CDH1 TET3

2.00e-04894235569195
Pubmed

The assembly of mammalian SWI/SNF chromatin remodeling complexes is regulated by lysine-methylation dependent proteolysis.

SMARCC1 ARID1A

2.00e-04894236335117
Pubmed

Epigenetic regulation by BAF (mSWI/SNF) chromatin remodeling complexes is indispensable for embryonic development.

SMARCC1 ARID1A

2.00e-04894226986003
Pubmed

A Genome-wide CRISPR Screen Reveals a Role for the Non-canonical Nucleosome-Remodeling BAF Complex in Foxp3 Expression and Regulatory T Cell Function.

SMARCC1 ARID1A

2.00e-04894232640256
Pubmed

miR-200c regulates FGFR-dependent epithelial proliferation via Vldlr during submandibular gland branching morphogenesis.

DAB1 CDH1

2.00e-04894222115756
Pubmed

STING-Mediated IFI16 Degradation Negatively Controls Type I Interferon Production.

EXOSC10 DDX52 MATR3 SMARCC1 SDAD1 RPL7A

2.23e-0431694631665637
Pubmed

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

MED6 ZNF609 TPX2 SMARCC1 DGCR8 ARID1A EMSY

2.35e-0445394729656893
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

EXOSC10 DDX52 MATR3 SMARCC1 MYO1B ARID1A SDAD1 RPL7A

2.40e-0460594828977666
InteractionPOU5F1 interactions

EXOSC10 PDPR AHNAK MATR3 SMARCC1 AFDN ARID1A CDH1 GCN1 AP3D1 MRPS22 EMSY

1.72e-055849412int:POU5F1
InteractionMEN1 interactions

SCYL2 EXOSC10 ZNF609 RBBP6 DDX52 MATR3 TPX2 RBM7 AFDN MYO1B ARID1A AP3D1 MRPS22 SDAD1 EMSY RPL7A

2.04e-0510299416int:MEN1
InteractionKIF20A interactions

ALMS1 KHDRBS3 RBBP6 AHNAK MATR3 GYS2 SPTB TPX2 MAP7D2 AFF1 MYO1B CDYL ALDH1B1 GCN1 TET3 EMSY

2.67e-0510529416int:KIF20A
InteractionPAFAH1B1 interactions

DNAI1 DCDC1 CAPN2 DAB1 ISOC1 ACAA2 ALDH1B1 RPL7A

2.79e-05258948int:PAFAH1B1
InteractionC9orf78 interactions

ACSL3 EXOSC10 DDX52 MATR3 CAPN2 TPX2 PI4K2A SMARCC1 AFDN MYO1B ACAA2 SDAD1

3.09e-056209412int:C9orf78
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

PTPN3 MYO15A KRIT1

5.80e-04505931293
GeneFamilyProtein tyrosine phosphatases, non-receptor type

PTPN3 PTPN12

1.55e-0318592812
CoexpressionAtlasdev gonad_e11.5_F_SupCellPrec_Sry_top-relative-expression-ranked_500

SCYL2 TGM3 PTPN3 DAB1 AFF1 AKT2 ACAA2 TMEM35A ALDH1B1 GALNT7

1.00e-054049210gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_500
CoexpressionAtlasDevelopingGonad_P2_testes_emap-30171_k-means-cluster#3_top-relative-expression-ranked_1000

FYTTD1 PDPR AKT2 ACAA2 ALDH1B1

3.22e-0584925gudmap_developingGonad_P2_testes_1000_k3
CoexpressionAtlasdev gonad_e11.5_F_SupCellPrec_Sry_top-relative-expression-ranked_1000

SCYL2 TGM3 PTPN3 PTPN12 AHNAK DAB1 AFF1 AKT2 ACAA2 TMEM35A ALDH1B1 RMND1 GALNT7

3.56e-057919213gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_top-relative-expression-ranked_1000

SEC24D CRACDL ERCC6L2 DZIP3 SMARCC1 ISOC1 ARHGAP28 CDYL GPC6 GCN1 BICC1 GSPT1 TGS1

4.60e-058119213gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000
CoexpressionAtlasDevelopingGonad_e18.5_testes_emap-11164_top-relative-expression-ranked_1000

INTS6L EXOSC10 FYTTD1 PDPR MAP7D2 SPOCK2 AKT2 ACAA2 ALDH1B1 GALNT7 ARID1A GPC6 BICC1

4.78e-058149213gudmap_developingGonad_e18.5_testes_1000
CoexpressionAtlasDevelopingGonad_e14.5_ testes_emap-6710_top-relative-expression-ranked_1000

INTS6L EXOSC10 FYTTD1 PDPR MAP7D2 AKT2 ACAA2 ALDH1B1 GALNT7 ARID1A GPC6 BICC1 DMXL1

5.28e-058229213gudmap_developingGonad_e14.5_ testes_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#5_top-relative-expression-ranked_1000

ERCC6L2 DZIP3 SMARCC1 ISOC1 CDYL GPC6 GCN1 GSPT1 TGS1

5.64e-05397929gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000_k5
CoexpressionAtlasDevelopingGonad_e11.5_testes_emap-3226_top-relative-expression-ranked_1000

INTS6L EXOSC10 FYTTD1 SMARCC1 ARHGAP28 ACAA2 DGCR8 GALNT7 ARID1A GPC6 BICC1 DMXL1 TGS1

6.82e-058439213gudmap_developingGonad_e11.5_testes_1000
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1

EXOSC10 ALMS1 TPX2 DZIP3 SMARCC1 ISOC1 GSPT1 DMXL1 TGS1

1.99e-04469929Facebase_RNAseq_e8.5_Floor Plate_2500_K1
CoexpressionAtlasDevelopingGonad_e12.5_testes_emap-29069_top-relative-expression-ranked_1000

INTS6L EXOSC10 FYTTD1 MATR3 ACAA2 DGCR8 GALNT7 ARID1A GPC6 BICC1 DMXL1 TGS1

2.14e-048199212gudmap_developingGonad_e12.5_testes_1000
CoexpressionAtlasDevelopingGonad_e16.5_testes_emap-8444_top-relative-expression-ranked_1000

INTS6L EXOSC10 FYTTD1 PDPR MAP7D2 AKT2 ACAA2 ALDH1B1 GALNT7 ARID1A GPC6 DMXL1

2.14e-048199212gudmap_developingGonad_e16.5_testes_1000
CoexpressionAtlasDevelopingGonad_P2_testes_emap-30171_top-relative-expression-ranked_1000

INTS6L EXOSC10 FYTTD1 PDPR SLC41A3 SPOCK2 AKT2 ACAA2 ALDH1B1 GALNT7 ARID1A BICC1

2.14e-048199212gudmap_developingGonad_P2_testes_1000
CoexpressionAtlasDevelopingGonad_e11.5_testes_emap-3226_k-means-cluster#2_top-relative-expression-ranked_1000

INTS6L EXOSC10 FYTTD1 ACAA2 GALNT7 BICC1

2.17e-04197926gudmap_developingGonad_e11.5_testes_k2_1000
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INTS6L TGM3 TTLL3 GON4L CDYL DUSP10

1.82e-06173946c31076c725f4cd912c56903592a2d9356ae59f54
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INTS6L TGM3 TTLL3 GON4L CDYL DUSP10

1.82e-06173946a4ed191cfdf6588b7f3672995bf0a4fe9e4b8df6
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DCDC1 SLC24A4 CRACDL MYO1B GPC6 BICC1

2.60e-0618494634e316ad8e7b8667cd8ad61397281802a252744f
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GSTT1 KHDRBS3 CAPN2 ERCC6L2 GPC6 BICC1

2.95e-061889466468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GSTT1 KHDRBS3 CAPN2 ERCC6L2 GPC6 BICC1

2.95e-061889467a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GSTT1 KHDRBS3 CAPN2 ERCC6L2 GPC6 BICC1

2.95e-061889469cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCellNS-moderate-d_0-4-Epithelial|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PTPN3 AHNAK CAPN2 AFDN CDH1 GSPT1

4.21e-0620094664462a18afca3c1a8548a857924b8166058bf958
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3_LINC00507_PSRC1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC24A4 PIK3C2G CRACDL GPC6 BICC1

2.63e-051659456de69b75174731931e7e80a3488f983a7ba4defe
ToppCellControl-B_intermediate-1|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

INTS6L AHNAK MATR3 AFDN GCN1

2.79e-05167945948504367ecf58144d9dd74d2ec531358fc4b309
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DCDC1 SLC24A4 CRACDL DAB1 BICC1

3.58e-05176945c7be4eaa5eb76ad9389fb9d15ad0934e88d267d1
ToppCellAT1_cells-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

CAPN2 AFDN MYO1B SPOCK2 CDH1

3.68e-051779453128b8d04687acee1ac4190b2569d6328b98eaf3
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC24A4 CRACDL MYO1B GPC6 BICC1

3.78e-05178945ccea3c8908d72f5fecd151a133048c8e9758304c
ToppCellfacs-Marrow-T-cells-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF2RB SLC41A3 AHNAK CAPN2 CDH1

4.10e-051819457286700396676fdc41d9723979b8b408177aceb9
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L2-4_RORB_GRIK1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

INTS6L SLC24A4 CRACDL DAB1 MYO1B

4.10e-0518194557994ff4ecffb15653aee00644d9f887f5e3461d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF609 ALMS1 CDYL GPC6 CDH1

4.20e-051829459174fb0b7ed8f721a5c513e41fd80476a9f34332
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DCDC1 SLC24A4 CRACDL MYO1B BICC1

4.32e-051839451645d4a55cd8c22d6eb47fc5c6b1e576c454f111
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D122|Adult / Lineage, Cell type, age group and donor

LRRC66 SH3D19 PODN GPC6 BICC1

4.43e-051849452b7e6f91e11c228f0521e099886867d9e998e78d
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RHBDF1 KHDRBS3 PODN GPC6 BICC1

4.78e-05187945ed7ab4cf4629d96dad5c74d536fc428d0a8d4eb9
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2G CRACDL SH3D19 MYO1B CDH1

4.78e-05187945f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D231|Adult / Lineage, Cell type, age group and donor

CAPN2 AFDN MYO1B SPOCK2 CDH1

5.03e-051899455a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CFAP47 PIK3C2G AFF1 MYO1B CDH1

5.16e-05190945078f4be52fa4cc8dd9c8d7a2b6d9631c3d902285
ToppCellControl-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

CFAP47 DNAI1 DCDC1 DZIP3 BICC1

5.56e-051939450e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

SMARCC1 IREB2 AFF1 ARID1A GSPT1

5.56e-05193945abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GSTT1 KHDRBS3 PODN GPC6 BICC1

5.69e-051949455594f7437448cb4b37d2d100f44d30c4a367df26
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2G AFF1 AFDN CDH1 TGS1

5.69e-0519494504bfc555743f7d8821439d05ae442d15e9886c59
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2G AFF1 AFDN CDH1 TGS1

5.69e-0519494569bff17df4a760ccf081cf52ff04af02c14f448d
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

CFAP47 DNAI1 DCDC1 CRACDL CDH1

5.83e-05195945fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCelldroplet-Heart-nan-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GSTT1 SH3D19 PODN GPC6 BICC1

5.83e-05195945613bea20c3d82c22a6af4c1a668af6fcf11fec0a
ToppCelldroplet-Heart-nan-18m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GSTT1 SH3D19 PODN GPC6 BICC1

5.83e-051959459ffabd831c2a0de3597f328e83db7ee259cb0ccc
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CAPN2 AFDN MYO1B SPOCK2 CDH1

5.83e-0519594568f4cc84b5ae7f4159b780c78e4b66c94211779a
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

CFAP47 DNAI1 DCDC1 CRACDL CDH1

5.83e-05195945eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CAPN2 AFDN MYO1B SPOCK2 CDH1

5.83e-051959452a1863f4b9fe73c30b0b1acf9b12fc98ef65040f
ToppCelllymphoid-T_cell-unlabelled(multiplets)|World / Lineage, cell class and subclass

CAPN2 DAB1 RBM7 SPOCK2 GSPT1

5.98e-0519694578b006922307c154622d71fcbc79ae5eed3f4b23
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT1-AT1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

AHNAK CAPN2 MYO1B SPOCK2 CDH1

5.98e-051969456731fef8c148b6681d6ed38afdf23c8213e0bbbe
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CAPN2 AFDN MYO1B SPOCK2 CDH1

5.98e-05196945eb68f7954e7c2f86d05e740e95b6e74805a6053f
ToppCellChildren_(3_yrs)-Mesenchymal|Children_(3_yrs) / Lineage, Cell type, age group and donor

SH3D19 PODN ARHGAP28 GPC6 BICC1

5.98e-05196945bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

AHNAK CAPN2 MYO1B SPOCK2 CDH1

5.98e-051969456856317cd0cdcb88fe54b4ae905d91e13495b1c4
ToppCellIPF-Epithelial|IPF / Disease state, Lineage and Cell class

CFAP47 DNAI1 DCDC1 CRACDL CDH1

5.98e-0519694587d9881cfec461a5d89b688a83749b618c519485
ToppCellnucseq-Mesenchymal-Fibroblastic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SH3D19 PODN ARHGAP28 GPC6 BICC1

5.98e-051969457d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCellBronchial-NucSeq-Stromal-Peri/Epineurial_|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PIK3C2G TPX2 PODN GPC6 BICC1

6.12e-05197945ee8f7def9d5af7b1e636830a4ea1da158d02f25a
ToppCellfacs-Tongue-nan-3m-Epithelial|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK SH3D19 MATR3 AFF1 CDH1

6.27e-051989452f03f8897dd7cce6d8296638e14e11ec16bcf624
ToppCellAdult-Mesenchymal|Adult / Lineage, Cell type, age group and donor

SH3D19 PODN ARHGAP28 GPC6 BICC1

6.27e-0519894526e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCellNS-critical-d_07-13|critical / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PTPN3 SH3D19 CAPN2 MYO1B CDH1

6.27e-05198945a6e11c87b31beffb6af190c64b4ef3ee1d9dab8d
ToppCellfacs-Tongue-nan-3m|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK SH3D19 MATR3 AFF1 CDH1

6.27e-05198945f2a4057f038ef7225a5b98a7ab068c30dff4eadd
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW13-Stem_cells|GW13 / Sample Type, Dataset, Time_group, and Cell type.

RBBP6 CAPN2 TPX2 ARID1A GPC6

6.42e-05199945fd1d1b95e01719e3d0a17d9d1f29717a47209d32
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

RBBP6 MATR3 DZIP3 GALNT7 AP3D1

6.42e-05199945fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCellNS-critical-d_07-13-Epithelial|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PTPN3 CAPN2 AFDN MYO1B CDH1

6.42e-05199945b88a81cd2a89f4d27100c96ae4324dcee68daf83
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GLRX5 RBBP6 AHNAK SPOCK2 GSPT1

6.42e-05199945f3cc3cda38f78d1d12d865df339d93c5fecf19f2
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW13-Stem_cells-Stem_cells|GW13 / Sample Type, Dataset, Time_group, and Cell type.

RBBP6 CAPN2 TPX2 ARID1A GPC6

6.42e-0519994591882af9dc7265c9b419f4415cbcf656087a2ab3
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3---L2-3|Neuronal / cells hierarchy compared to all cells using T-Statistic

SLC24A4 PIK3C2G CRACDL GPC6 BICC1

6.58e-052009459c89e91bb630cc306a820927a36ea6fb3d13e9d7
ToppCellTracheal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ACSL3 PTPN3 CRACDL GALNT7 CDH1

6.58e-05200945d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3-|Neuronal / cells hierarchy compared to all cells using T-Statistic

SLC24A4 PIK3C2G CRACDL GPC6 BICC1

6.58e-052009458821574d17b55dfea3ca0204e6b4c0ca6b19588a
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)|Neuronal / cells hierarchy compared to all cells using T-Statistic

SLC24A4 CRACDL MYO1B GPC6 BICC1

6.58e-052009450f23e72649a274043bf23e0952a9b5707c516acf
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3--|Neuronal / cells hierarchy compared to all cells using T-Statistic

SLC24A4 PIK3C2G CRACDL GPC6 BICC1

6.58e-0520094596b1d2e70fbbba744fd4356a70efcf356aca9abc
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Neuronal-Intermediate|GW23 / Sample Type, Dataset, Time_group, and Cell type.

LRRC66 PDPR TTLL3 AHNAK WDR81

6.58e-05200945fe772d98c461c973dfc082e1fc50117c27ced804
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3|Neuronal / cells hierarchy compared to all cells using T-Statistic

SLC24A4 PIK3C2G CRACDL GPC6 BICC1

6.58e-05200945ad6f1d4d7f5d7bab2ba2e4fff58c535290065c0e
ToppCellSevere-B_intermediate-1|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

INTS6L PIK3C2G AHNAK MATR3

9.02e-051119447021009545178fac1f19f3c429bfedb2f38b680d
ToppCellSevere-B_intermediate-1|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

INTS6L AHNAK MATR3 AFDN

1.47e-0412694442a0bdbe18ef85146cac4e86b2b27d0b3b20d8a2
ToppCellControl-B_intermediate-1|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

INTS6L AHNAK MATR3 AFDN

2.45e-04144944984470ff6ddce4c743e2db78fa98dae055aaa273
ToppCellCOVID-19_Mild-PLT_5|World / Disease Group and Platelet Clusters

INTS6L AHNAK MATR3 SPOCK2

3.02e-0415294490ba4e8a735ec8921038fa072129535f0e3fd9ae
ToppCell3'_v3-blood-Lymphocytic_T_CD4-Trm_Th1/Th17|blood / Manually curated celltypes from each tissue

DZIP3 AFDN SPOCK2 GSPT1

3.09e-04153944d09bc7322b59f613d66673359ee6af1aea99ce87
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP47 ALMS1 AFF1 SPOCK2

3.25e-04155944441fcb6d05364fc6f4973f0b973f1a80b573ce1f
ToppCellfacs-Marrow-T-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF2RB SLC41A3 POLN CDH1

3.41e-04157944ed9c9feefc06c9536c03bedbc3397a2ee492a78e
ToppCellfacs-Marrow-T-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF2RB SLC41A3 POLN CDH1

3.41e-04157944fddcb24776b9f86e000208bae54541b15b2adefd
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2G AFF1 MYO1B CDH1

3.66e-041609447064af50fc10e3ea03badf415306222b74db0f95
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGM3 SLC15A1 AHNAK CAPN2

3.84e-04162944bc63a96ad3ba0b3433e3679d7a005f47709ff384
ToppCell343B-Fibroblasts-Fibroblast-D-|343B / Donor, Lineage, Cell class and subclass (all cells)

PODN ALDH1B1 GPC6 BICC1

3.93e-041639448d2b2119c6b3d5b677da6f377fd85146590e1246
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCYL2 ZNF609 ALMS1 PIK3C2G

3.93e-04163944d2fcd6f561748f7d29a051c504f016952ba32d0f
ToppCell343B-Fibroblasts-Fibroblast-D|343B / Donor, Lineage, Cell class and subclass (all cells)

PODN ALDH1B1 GPC6 BICC1

3.93e-04163944acfb2ece6202479e615d54fd3ecb8b4a571b5a18
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CFAP47 DNAI1 DCDC1 CDH1

4.11e-041659440c714e852f912b5749de4cb0895406673979b2e6
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_1|COVID-19_Mild / Disease condition and Cell class

DCDC1 MATR3 DAB1 EMSY

4.11e-04165944ef709c5d3231c65d351316e1e31b9c9eba721628
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CFAP47 DNAI1 DCDC1 CDH1

4.11e-0416594482530f96aaefe28a13bad0474bbad043f127a86c
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

SMARCC1 GON4L AFDN ARID1A

4.21e-0416694432d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCellfacs-Marrow-T_cells-18m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF2RB SLC41A3 POLN CDH1

4.21e-04166944c22b0f3bf990d94b615a3aacee5de548da2db628
ToppCellfacs-Marrow-T_cells-18m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF2RB SLC41A3 POLN CDH1

4.21e-041669440975fc165bcc7e85f053d9d0244fffe407c23571
ToppCellfacs-Lung-EPCAM-24m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INTS6L DNAI1 PTPN12 ACR

4.31e-04167944961e722442d786ab15d1e490941d2be265a9057a
ToppCellTCGA-Head_and_Esophagus-Solid_Tissue_Normal-Head_and_Neck-Head_and_Neck_normal_tissue-6|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

PPP1R3A TGM3 GYS2 TMPRSS11B

4.31e-041679444a533972a0f40fff82dccf8e64716cb34f75736e
ToppCellfacs-Lung-EPCAM-24m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INTS6L DNAI1 PTPN12 ACR

4.31e-041679443760efc35d4e7e9c2da1a20f9795ddea397e2206
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D175|Adult / Lineage, Cell type, age group and donor

MATR3 SPTB GPC6 BICC1

4.31e-04167944c4e321bb87512ea839f324c92c0f1afea891483f
ToppCelldroplet-Lung-18m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CSF2RB SLC41A3 POLN CDH1

4.40e-041689440e99ecd94ab8e5372e30433d7d0aa76b4d54257a
ToppCelldroplet-Lung-18m-Hematologic-myeloid-Basophil/Mast_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CSF2RB SLC41A3 POLN CDH1

4.40e-0416894434722e14f28313f2e4644b3c1861ef12958cee9f
ToppCelldroplet-Lung-nan-18m-Myeloid-Basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF2RB SLC41A3 POLN CDH1

4.50e-04169944f2e20049a17eee533d49bd5f24a51962d123d132
ToppCelldroplet-Lung-nan-3m-Myeloid-basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF2RB POLN CDH1 SLC29A2

4.50e-04169944da607c1d068038d5a3d1117f6aa6e4c6f3552e97
ToppCelldroplet-Lung-nan-3m-Myeloid-Basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF2RB POLN CDH1 SLC29A2

4.50e-04169944a14b46231e079a0fd9f3ca13d5d48113be76fd0f
ToppCelldroplet-Lung-nan-18m-Myeloid-basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF2RB SLC41A3 POLN CDH1

4.50e-041699444c6892551e9dec94fc62b3beab1e6d424639a1e9
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TPX2 MAP7D2 SPOCK2 EHD3

4.50e-04169944dbf9b1d52b29bf4b60bd23012cc1ea82d344747f
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AHNAK DAB1 SPOCK2 BICC1

4.50e-041699448f397cf4f9fd7c6fa88d01a95289ce2a6bc6938d
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTPN3 PIK3C2G AFF1 CDH1

4.60e-04170944928e42c51a7079c506f21c669c4e4c1a0df84d77
ToppCellControl-B_naive-1|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

INTS6L MATR3 RGPD1 EMSY

4.71e-04171944d18855b24aadea38fd1e4592f945cf15b85e05f1
ToppCelldroplet-Lung-nan-21m-Myeloid-Basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF2RB SLC41A3 POLN CDH1

4.81e-041729441b133be191252e7053faeacf9547730c3ae28d21
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Red_blood_cells|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GLRX5 SPTB RGPD1 GSPT1

4.81e-04172944cc1a45a35f78063b2a777ae905f70f894fbcb22f
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Red_blood_cells-RBC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GLRX5 SPTB RGPD1 GSPT1

4.81e-0417294430c57f5ca2326e8d890d9aac8096c64e5b51a24f
ToppCelldroplet-Lung-nan-21m-Myeloid-basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF2RB SLC41A3 POLN CDH1

4.81e-04172944b3c53fd7e50f36de6a8585ae21d04e17932f262c
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC24A4 PIK3C2G CRACDL BICC1

5.03e-041749449cc7251661ea2b1565eef1dfb8cf6dec3ade13d4
ToppCelldroplet-Lung-21m-Hematologic-myeloid-Basophil/Mast_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CSF2RB SLC41A3 POLN CDH1

5.03e-0417494431f7127faabcb1092bb9827db625f57cf7d8240e
ToppCellInt-URO-Lymphocyte-T_NK-MAIT|Int-URO / Disease, Lineage and Cell Type

PTPN3 DAB1 SPOCK2 ACAA2

5.03e-041749445227ed29f5f0d3e0aaa7f3cfd362f96d3e2660f7
ToppCellControl-Epithelial_cells-AT1|Control / group, cell type (main and fine annotations)

AFDN MYO1B SPOCK2 CDH1

5.03e-04174944548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCelldroplet-Lung-21m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CSF2RB SLC41A3 POLN CDH1

5.03e-041749448a8e98e62c2859c004b44dbce6974c9639ebeac6
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC24A4 CRACDL DAB1 BICC1

5.25e-0417694407abf29d681abdd6c7cc87f9eaf9377e92ce212c
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-4|TCGA-Lung / Sample_Type by Project: Shred V9

SEC24D SPTB GPC6 BICC1

5.25e-041769440923b01137d6f9956ca815b41102c81e82624065
DrugMethylergometrine maleate [113-42-8]; Down 200; 8.8uM; PC3; HT_HG-U133A

DZIP3 IREB2 ACAA2 ALDH1B1 RMND1 AP3D1 KRIT1 TGS1

1.27e-061939386704_DN
DrugAmyleine hydrochloride [532-59-2]; Down 200; 14.8uM; PC3; HG-U133A

RBBP6 DZIP3 TRMT11 ISOC1 MYO1B DMXL1 KRIT1 TGS1

1.42e-061969381909_DN
Drug32 P

PPP1R3A GSTT1 PTPN3 RHBDF1 SLC24A4 GYS2 SPTB POLN AP3D1 KRIT1

6.17e-064059310CID000448772
Drugirinotecan HCl; Down 200; 100uM; MCF7; HT_HG-U133A

SCYL2 MED6 PTPN12 TPX2 TRMT11 CDYL CDH1

1.02e-051839377498_DN
DrugTocainide hydrochloride; Down 200; 17.4uM; MCF7; HT_HG-U133A

GSTT1 ZNF609 PI4K2A DZIP3 DUSP10 SLC29A2 EMSY

1.54e-051959377351_DN
DrugRisperidone [106266-06-2]; Up 200; 9.8uM; MCF7; HT_HG-U133A

ZNF609 CAPN2 PI4K2A GON4L DUSP10 DGCR8 GSPT1

1.60e-051969373508_UP
DrugSulfadimethoxine [122-11-2]; Up 200; 12.8uM; MCF7; HT_HG-U133A

MED6 RBBP6 PI4K2A GON4L AFF1 ACAA2 DGCR8

1.60e-051969374724_UP
DrugButacaine [149-16-6]; Down 200; 13uM; HL60; HT_HG-U133A

GSTT1 RHBDF1 CAPN2 AFF1 AFDN MYO1B ALDH1B1

1.65e-051979372728_DN
DrugN-Acetyl-L-leucine [1188-21-2]; Down 200; 23uM; PC3; HT_HG-U133A

ZNF609 ALMS1 CAPN2 GON4L MYO1B EMSY KRIT1

1.65e-051979374622_DN
DrugSaquinavir mesylate [149845-06-7]; Down 200; 5.2uM; MCF7; HT_HG-U133A

SEC24D MED6 ALMS1 ISOC1 IREB2 ALDH1B1 EHD3

1.70e-051989376246_DN
DrugMethyldopate hydrochloride [2508-79-4]; Up 200; 14.6uM; PC3; HT_HG-U133A

ZNF609 SPTB CAPN2 AFF1 ARHGAP28 DGCR8 KRIT1

1.70e-051989376640_UP
DrugP-44

ACR PODN ACAA2

2.90e-0515933CID000200876
Drugretinoic acid; Down 200; 1uM; MCF7; HT_HG-U133A

SCYL2 MED6 PTPN12 AHNAK IREB2 CDH1

1.30e-041909361636_DN
DrugDesipramine hydrochloride [58-28-6]; Up 200; 13.2uM; PC3; HT_HG-U133A

SEC24D ZNF609 AHNAK SPTB MYO1B BICC1

1.34e-041919366693_UP
DrugSanguinarine [2447-54-3]; Down 200; 12uM; MCF7; HT_HG-U133A

ALMS1 DDX52 AHNAK PI4K2A DZIP3 AFF1

1.34e-041919364168_DN
DrugGSK-3 Inhibitor IX; Down 200; 0.5uM; PC3; HT_HG-U133A

MATR3 CAPN2 DUSP10 EMSY KRIT1 EHD3

1.38e-041929367106_DN
DrugTranylcypromine hydrochloride [1986-47-6]; Down 200; 23.6uM; PC3; HT_HG-U133A

SCYL2 ALMS1 SMARCC1 GON4L IREB2 DUSP10

1.38e-041929362101_DN
DrugMonobenzone [103-16-2]; Down 200; 20uM; HL60; HT_HG-U133A

ZNF609 KHDRBS3 AFDN MYO1B ALDH1B1 ARID1A

1.38e-041929363054_DN
DrugWY-14643; Down 200; 100uM; PC3; HG-U133A

GSTT1 SEC24D SPTB PI4K2A DGCR8 ARID1A

1.38e-04192936464_DN
DrugAlprenolol hydrochloride [13707-88-5]; Up 200; 14uM; MCF7; HT_HG-U133A

AHNAK SPTB PI4K2A AKT2 DUSP10 DGCR8

1.42e-041939366789_UP
DrugDomperidone maleate; Down 200; 7.4uM; MCF7; HT_HG-U133A

SCYL2 MED6 PTPN12 SMARCC1 ALDH1B1 CDH1

1.46e-041949362655_DN
DrugVerteporfin [129497-78-5]; Up 200; 2.8uM; MCF7; HT_HG-U133A

ZNF280A SEC24D ZNF609 KHDRBS3 PI4K2A GSPT1

1.46e-041949363556_UP
DrugDexamethasone acetate [1177-87-3]; Down 200; 9.2uM; HL60; HG-U133A

SEC24D ZNF609 TRMT11 ISOC1 RMND1 KRIT1

1.46e-041949361396_DN
DrugGuaifenesin [93-14-1]; Down 200; 20.2uM; MCF7; HT_HG-U133A

MED6 ALMS1 SMARCC1 DUSP10 ALDH1B1 BIN3

1.46e-041949363431_DN
DrugICI 182,780; Up 200; 1uM; MCF7; HT_HG-U133A

AHNAK GON4L MYO1B SPOCK2 ARID1A EMSY

1.50e-041959361630_UP
DrugSTOCK1N-35874; Up 200; 14uM; PC3; HT_HG-U133A

SCYL2 PTPN12 SLC41A3 SMARCC1 ALDH1B1 RMND1

1.50e-041959366583_UP
DrugPHA-00665752 [477575-56-7]; Down 200; 10uM; MCF7; HT_HG-U133A

SCYL2 MED6 PTPN12 DZIP3 CDYL CDH1

1.50e-041959366578_DN
DrugCholecalciferol [67-97-0]; Down 200; 10.4uM; HL60; HT_HG-U133A

SEC24D ZNF609 IREB2 MYO1B DGCR8 KRIT1

1.54e-041969362436_DN
DrugTetracycline hydrochloride [64-75-5]; Up 200; 8.4uM; MCF7; HT_HG-U133A

ZNF280A SLC15A1 AHNAK PI4K2A SPOCK2 AKT2

1.54e-041969362243_UP
DrugMifepristone [84371-65-3]; Down 200; 9.4uM; HL60; HG-U133A

SLC41A3 SMARCC1 AFF1 MYO1B SPOCK2 AP3D1

1.54e-041969361569_DN
DrugBretylium tosylate [61-75-6]; Down 200; 9.6uM; MCF7; HT_HG-U133A

MED6 ALMS1 PI4K2A MYO1B ARID1A GSPT1

1.54e-041969365020_DN
DrugPaclitaxel [33069-62-4]; Down 200; 4.6uM; PC3; HG-U133A

ACSL3 ALMS1 RBBP6 ISOC1 MYO1B SPOCK2

1.54e-041969361959_DN
DrugMuramic acid, N-acetyl [10597-89-4]; Up 200; 13.6uM; PC3; HT_HG-U133A

AHNAK PI4K2A ARHGAP28 AKT2 EMSY GSPT1

1.54e-041969364582_UP
DrugPhenethicillin potassium salt [132-93-4]; Down 200; 10uM; MCF7; HT_HG-U133A

SEC24D MYO1B AKT2 DUSP10 ALDH1B1 GSPT1

1.59e-041979366105_DN
Drug1,1-dimethylbiguanide hydrochloride; Down 200; 0.1uM; MCF7; HG-U133A

ALMS1 RBBP6 DDX52 CDYL ACAA2 AP3D1

1.59e-041979363_DN
DrugCinchonine [118-10-5]; Up 200; 13.6uM; PC3; HT_HG-U133A

MED6 AHNAK PI4K2A SPOCK2 GSPT1 KRIT1

1.59e-041979363988_UP
DrugCyanocobalamin [68-19-9]; Up 200; 3uM; PC3; HT_HG-U133A

AHNAK ARHGAP28 DGCR8 CDH1 ATP2B2 GSPT1

1.59e-041979364572_UP
DrugMethimazole [60-56-0]; Down 200; 35uM; MCF7; HT_HG-U133A

SEC24D SPTB AFF1 AKT2 ACAA2 ARID1A

1.63e-041989363898_DN
Drugbeta- Belladonnine dichloroethylate [191355-47-2]; Down 200; 6uM; HL60; HT_HG-U133A

GSTT1 SEC24D ZNF609 AHNAK ALDH1B1 GSPT1

1.63e-041989362164_DN
DrugEthambutol dihydrochloride [1070-11-7]; Down 200; 14.4uM; PC3; HG-U133A

GSTT1 ZNF609 RHBDF1 MATR3 TRMT11 ARID1A

1.63e-041989361900_DN
DrugKetorolac tromethamine [74103-07-4]; Up 200; 10.6uM; HL60; HT_HG-U133A

ZNF280A KHDRBS3 SPTB PI4K2A ALDH1B1 GSPT1

1.63e-041989363110_UP
DrugMyricetin [529-44-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A

ZNF609 AHNAK PI4K2A MYO1B ARID1A EMSY

1.63e-041989363270_UP
DrugCyclopenthiazide [742-20-1]; Down 200; 10.6uM; MCF7; HT_HG-U133A

GSTT1 SEC24D DDX52 DZIP3 AKT2 DUSP10

1.63e-041989367325_DN
DrugRemoxipride Hydrochloride [73220-03-8]; Down 200; 9.8uM; MCF7; HT_HG-U133A

SEC24D MED6 PI4K2A GON4L AKT2 DGCR8

1.68e-041999365443_DN
DrugProtoveratrine A [143-57-7]; Up 200; 5uM; PC3; HT_HG-U133A

ZNF609 AFDN MYO1B AKT2 ARID1A GSPT1

1.68e-041999366618_UP
DrugVidarabine [5536-17-4]; Down 200; 15uM; HL60; HT_HG-U133A

RHBDF1 DZIP3 MYO1B DGCR8 ALDH1B1 EHD3

1.68e-041999362706_DN
DrugCiprofloxacin hydrochloride [93107-08-5]; Up 200; 10.8uM; PC3; HT_HG-U133A

AHNAK AFDN MYO1B SPOCK2 DGCR8 ALDH1B1

1.68e-041999366700_UP
DrugFlucytosine [2022-85-7]; Down 200; 31uM; PC3; HT_HG-U133A

MED6 RHBDF1 ALMS1 ARHGAP28 KRIT1 TGS1

1.72e-042009366690_DN
DiseaseAlzheimer disease

SLC24A4 PIK3C2G DAB1 WDR81 AFF1 POLN MYO15A GPC6 DMXL1

1.93e-05485919MONDO_0004975
Diseaseserum gamma-glutamyl transferase measurement

PTPN3 SLC24A4 AHNAK GYS2 GON4L AFF1 MYO1B ARID1A GCN1 EMSY BICC1

1.17e-049149111EFO_0004532
Diseasehydrocephalus (is_implicated_in)

WDR81 SMARCC1

1.40e-046912DOID:10908 (is_implicated_in)
Diseasehypoglycemia (is_implicated_in)

PPP1R3A AKT2

2.60e-048912DOID:9993 (is_implicated_in)
Diseasetype 2 diabetes mellitus (implicated_via_orthology)

PPP1R3A ALMS1 AFF1 AKT2

3.19e-04105914DOID:9352 (implicated_via_orthology)
DiseaseCoffin-Siris syndrome (implicated_via_orthology)

SMARCC1 ARID1A

3.34e-049912DOID:1925 (implicated_via_orthology)
Diseaseprostate cancer (is_implicated_in)

ACSL3 GSTT1 AKT2 CDH1

4.81e-04117914DOID:10283 (is_implicated_in)
Diseaseprotein-glutamine gamma-glutamyltransferase e measurement

TGM3 PTPN3 AHNAK

8.55e-0460913EFO_0020690
Diseasebreast cancer (is_implicated_in)

ACSL3 GSTT1 ARID1A CDH1

1.22e-03150914DOID:1612 (is_implicated_in)
DiseaseBreast Carcinoma

TRMT11 AKT2 RMND1 ARID1A CDH1 MRPS22 EMSY

1.39e-03538917C0678222
Diseasered blood cell density measurement

PTPN3 GLRX5 DCDC1 TPX2 AFF1 AFDN ACAA2 MYO15A AP3D1

1.58e-03880919EFO_0007978
DiseaseMalignant neoplasm of breast

PPP1R3A TRMT11 MAP7D2 AFF1 AKT2 RMND1 ARID1A CDH1 MRPS22 EMSY

1.75e-0310749110C0006142
Diseasetype 2 diabetes mellitus (is_implicated_in)

PPP1R3A GSTT1 PIK3C2G AKT2

1.97e-03171914DOID:9352 (is_implicated_in)
DiseaseNasopharyngeal carcinoma

AKT2 ARID1A

2.09e-0322912C2931822
Diseaseglycerol measurement

TGM3 HERC2P3

2.91e-0326912EFO_0010115
DiseaseCholangiocarcinoma

PTPN3 ARID1A

2.91e-0326912C0206698

Protein segments in the cluster

PeptideGeneStartEntry
QNKTFDPKKENPIVL

ZNF280A

261

P59817
DVVQKKLLPPFKPQV

AKT2

416

P31751
FVLKNENDAIPPKKA

AFDN

126

P55196
LVKKGFNPPVLVFVQ

DDX52

406

Q9Y2R4
KEITYGNNKPVKAPL

ACR

106

P10323
EIFGPVQPLFKFKKI

ALDH1B1

416

P30837
KRKPDVVTPNGLNVK

GYS2

271

P54840
KKQPNLPDVKVAGLV

SPATA5

581

Q8NB90
EPGNQKLRKAPVKFA

ALMS1

3231

Q8TCU4
IPDVNVNLKGPKIKG

AHNAK

5196

Q09666
PKEKKGQEVQKGPAV

DNAI1

666

Q9UI46
DAPTKKEFVINPNGK

DGCR8

496

Q8WYQ5
EQLDVFISIKPKPKQ

BICC1

376

Q9H694
SIFEPVNLPKQKKNL

DMXL1

81

Q9Y485
EKRKQIFGQNFIPPK

ATP2B2

76

Q01814
AGELNPVAPKAQKKV

AP3D1

601

O14617
PIQITTPKNFKGKED

POLN

586

Q7Z5Q5
LGQVKEKPQYGKNPV

SLC24A4

291

Q8NFF2
VGKKPPQEIGIKVKN

INTS6L

441

Q5JSJ4
NIKLFNKFIGKPAPK

IREB2

801

P48200
LGEKFPDKKPKVQLV

PIK3C2G

1321

O75747
KKPGLAITFAKLPQN

PTPN3

656

P26045
KLPVKIVQKNDPFVV

ARID1A

1811

O14497
KNNKLEKIPPGAFSE

PODN

246

Q7Z5L7
KTQKPFLQGPFKVIS

DCDC1

1351

M0R2J8
PKFKEIQNLIKASAP

ISOC1

276

Q96CN7
RIKKPEGKPDQKFDQ

MATR3

476

P43243
VSPQVKKEDPKVGVQ

MAP7D2

556

Q96T17
PRPQVKLFGKEKLEV

MYO15A

481

Q9UKN7
EGKAVAKEVPPLQQK

KIAA2026

1116

Q5HYC2
KFVKGKRPIISPNLN

DUSP10

436

Q9Y6W6
QFKEIQKLIKEPAPD

ISOC2

176

Q96AB3
EKNPKPIFTEGKNQL

PDPR

306

Q8NCN5
GAPDYSKIQIPKQEK

KRIT1

256

O00522
FRKPPVFLKKGDEVQ

FAHD2A

286

Q96GK7
KVGIALKPFLPQLQT

GCN1

2336

Q92616
PVKPAVDRKQGAKLN

CRACDL

886

Q6NV74
INTLPKGVVPHIKKF

DZIP3

61

Q86Y13
LVPFLKKVGFNPKKD

GSPT1

241

P15170
PPQAFKDLKKLQVID

LRRC66

211

Q68CR7
KENIVKPAKGPQEKV

RBBP6

1031

Q7Z6E9
PVNFPNKAEGLEKKQ

PPP1R3A

346

Q16821
KDPQGRIIAVFKPKN

PI4K2A

141

Q9BTU6
TPFLPKIFIKPNAQK

EXOSC10

196

Q01780
KIFIKPNAQKPLPQA

EXOSC10

201

Q01780
PEIKNLDQAFQVKKP

CSF2RB

846

P32927
QLKPFGDVPRKLKIQ

GPC6

196

Q9Y625
KDKVVVFLKGTPEQP

GLRX5

51

Q86SX6
QKKEGVYDVPKSQPV

DAB1

226

O75553
QFKKPIIVAVNGPAI

CDYL

436

Q9Y232
FRKPPVFLKKGDEVQ

FAHD2B

286

Q6P2I3
EKAKPLVLGPEFKQA

GALNT7

151

Q86SF2
SPIKKANEIKPPQFV

GON4L

346

Q3T8J9
FKIGQPKKQIVPKTV

BIN3

6

Q9NQY0
LGQKVLIPVKQFPKF

KHDRBS3

56

O75525
LIPVKQFPKFNFVGK

KHDRBS3

61

O75525
QGKTQVLIKPKPVTF

EMSY

661

Q7Z589
PLKQLQEVKFVKDCP

ERCC6L2

76

Q5T890
PPNLFKIIQKALQKG

CAPN2

221

P17655
LPVFPKGNEVQIKVL

SLC15A1

386

P46059
NQKIRFKEPVKPQFK

CFAP47

71

Q6ZTR5
NEKGPFPKNLVQIKS

CDH1

166

P12830
KFVQLKPGEKPVPVD

MED6

191

O75586
FQVPRPKIKLIKGEA

RGPD1

316

P0DJD0
AQVNPLKKVPALKDG

GSTT1

46

P30711
NLQKTFKPAIQELKP

MRPS22

86

P82650
HQAGPVIKVKIPKDK

RBM7

31

Q9Y580
LEFLPFEGKVNLKKP

TRMT11

131

Q7Z4G4
QKPGKPSVFTVFQKI

SLC29A2

276

Q14542
KAKSQVFKNQDPVLP

SH3D19

386

Q5HYK7
KVVNPLFEKRPKNFG

RPL7A

26

P62424
FEIKKVPLQEGPKSF

PTPN12

436

Q05209
KQKEGAAAPQPKVRL

RHBDF1

326

Q96CC6
VKLILPELGPVFKQQ

SCYL2

406

Q6P3W7
VPKQDFPQVKRPLKA

RMND1

136

Q9NWS8
IAKQSPPIVKILKFG

SLC41A3

271

Q96GZ6
NVEIFKLQPNKPSKE

SDAD1

41

Q9NVU7
KFKELGIQPVPLQTI

HERC2P3

481

Q9BVR0
PEKNKEKPVDLQNFG

SMARCC1

586

Q92922
GNALVVDPKKPFRKL

EHD3

111

Q9NZN3
AKQAQIPLAAVIKPF

SEC24D

326

O94855
QVFQKALGKLKPNTP

TGM3

451

Q08188
KPGKPQVKFDKQQAD

AFF1

951

P51825
EVQPNGKIFKKVILG

ACSL3

116

O95573
QLQKLPPVFKKDGTV

ACAA2

231

P42765
DVKKVPKGVPLQFDI

FYTTD1

266

Q96QD9
VQLQLKFKFPPAEGV

TMPRSS11B

111

Q86T26
KKDPGVKVPLVLQKF

ARHGAP28

391

Q9P2N2
KVVFQKGPPEIKIAD

TEX43

96

Q6ZNM6
VKEGAKKTLFPPQPQ

ZNF609

871

O15014
EKPPKFQEKGNLEVL

SPTB

351

P11277
PKKQEKNPVLVSPEF

TTLL3

181

Q9Y4R7
VAEPQQKEKKGVVPT

TET3

1751

O43151
KKNKKVNGLPPEIAA

TGS1

626

Q96RS0
FEPVAKALGPKNANK

WDR81

946

Q562E7
QIQEAAKKKPGIFIP

SPOCK2

321

Q92563
KELQKGEVPKFKALP

TPX2

556

Q9ULW0
KSLFPEGNPAKINLK

MYO1B

551

O43795
EQPSLYEKAPQGKVK

TMEM35A

151

Q53FP2