Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone H4K12 acetyltransferase activity

BRPF3 KAT2A BRPF1

9.22e-05121533GO:0043997
GeneOntologyCellularComponentmulti-pass translocon complex

NOMO1 NOMO2 NOMO3

3.07e-0591523GO:0160064
GeneOntologyCellularComponentER membrane insertion complex

NOMO1 NOMO2 NOMO3

1.29e-04141523GO:0072379
GeneOntologyCellularComponentmucus layer

MUC2 MUC5AC

1.57e-0431522GO:0070701
GeneOntologyCellularComponentextracellular matrix

VWF FN1 CILP ADAMTS1 LAMA4 MUC5B BCAN ITGB4 LRIG3 LRRN3 TLR3 MUC2 USH2A MUC5AC

3.17e-0465615214GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

VWF FN1 CILP ADAMTS1 LAMA4 MUC5B BCAN ITGB4 LRIG3 LRRN3 TLR3 MUC2 USH2A MUC5AC

3.27e-0465815214GO:0030312
GeneOntologyCellularComponentribose phosphate diphosphokinase complex

PRPS1L1 PRPS1

5.18e-0451522GO:0002189
DomainWxxW_domain

CILP MUC5B MUC2 MUC5AC

6.25e-0861524IPR025155
DomainMucin2_WxxW

CILP MUC5B MUC2 MUC5AC

6.25e-0861524PF13330
DomainC8

VWF MUC5B MUC2 MUC5AC

1.98e-06121524PF08742
DomainTIL

VWF MUC5B MUC2 MUC5AC

1.98e-06121524PF01826
DomainLamGL

PAPPA2 PAPPA USH2A

2.10e-0641523SM00560
DomainDUF2012

NOMO1 NOMO2 NOMO3

2.10e-0641523PF09430
DomainLamG-like

PAPPA2 PAPPA USH2A

2.10e-0641523IPR006558
DomainDUF2012

NOMO1 NOMO2 NOMO3

2.10e-0641523IPR019008
DomainUnchr_dom_Cys-rich

VWF MUC5B MUC2 MUC5AC

2.85e-06131524IPR014853
DomainC8

VWF MUC5B MUC2 MUC5AC

2.85e-06131524SM00832
DomainSushi

PAPPA2 BCAN CSMD2 CR1 PAPPA CSMD1

3.93e-06521526PF00084
DomainTIL_dom

VWF MUC5B MUC2 MUC5AC

3.96e-06141524IPR002919
DomainCCP

PAPPA2 BCAN CSMD2 CR1 PAPPA CSMD1

4.92e-06541526SM00032
DomainSUSHI

PAPPA2 BCAN CSMD2 CR1 PAPPA CSMD1

6.11e-06561526PS50923
DomainSushi_SCR_CCP_dom

PAPPA2 BCAN CSMD2 CR1 PAPPA CSMD1

6.78e-06571526IPR000436
DomainVWF_type-D

VWF MUC5B MUC2 MUC5AC

7.11e-06161524IPR001846
DomainVWFD

VWF MUC5B MUC2 MUC5AC

7.11e-06161524PS51233
DomainVWD

VWF MUC5B MUC2 MUC5AC

7.11e-06161524SM00216
DomainVWD

VWF MUC5B MUC2 MUC5AC

7.11e-06161524PF00094
DomainEGF_1

STAB2 FN1 FAT3 NOTCH2NLA LAMA4 BCAN NOTCH2NLC LRP1B ITGB4 CELSR2 USH2A

7.87e-0625515211PS00022
DomainCarboxyPept-like_regulatory

CILP NOMO1 NOMO2 NOMO3

9.24e-06171524IPR008969
DomainCTCK_1

VWF MUC5B MUC2 MUC5AC

1.18e-05181524PS01185
DomainVWC_out

VWF MUC5B MUC2 MUC5AC

1.49e-05191524SM00215
DomainCT

VWF MUC5B MUC2 MUC5AC

2.75e-05221524SM00041
DomainCarb-bd-like_fold

NOMO1 NOMO2 NOMO3

2.87e-0581523IPR013784
Domain-

PAPPA2 FN1 DSCAM CILP MYCBP2 AXL BCAN HEPACAM2 ITGB4 NOMO1 LRIG3 BTN2A2 LRRN3 NOMO2 PLXNC1 USH2A NOMO3

2.91e-05663152172.60.40.10
DomainCys_knot_C

VWF MUC5B MUC2 MUC5AC

4.67e-05251524IPR006207
DomainCTCK_2

VWF MUC5B MUC2 MUC5AC

4.67e-05251524PS01225
DomainBromodomain_CS

BRPF3 CECR2 KAT2A BRPF1

5.48e-05261524IPR018359
DomainEGF-like_CS

STAB2 FN1 FAT3 NOTCH2NLA LAMA4 BCAN NOTCH2NLC LRP1B ITGB4 CELSR2

5.63e-0526115210IPR013032
DomainIg-like_fold

PAPPA2 FN1 DSCAM CILP MYCBP2 AXL BCAN HEPACAM2 ITGB4 NOMO1 LRIG3 BTN2A2 LRRN3 NOMO2 PLXNC1 USH2A NOMO3

6.36e-0570615217IPR013783
DomainPeptidase_M43

PAPPA2 PAPPA

6.58e-0521522IPR008754
DomainPeptidase_M43

PAPPA2 PAPPA

6.58e-0521522PF05572
DomainConA-like_dom

PAPPA2 FAT3 LAMA4 ITGB4 BTN2A2 CELSR2 PAPPA TRIM47 USH2A

7.83e-052191529IPR013320
DomainEGF_LAM_2

STAB2 LAMA4 CELSR2 USH2A

9.80e-05301524PS50027
DomainEGF_LAM_1

STAB2 LAMA4 CELSR2 USH2A

9.80e-05301524PS01248
Domain-

PAPPA2 FAT3 LAMA4 CELSR2 PAPPA USH2A

1.26e-049515262.60.120.200
DomainLRRCT

LRIG3 LRRN3 LGI3 TLR3

1.27e-04321524PF01463
DomainCarboxyPept_regulatory_dom

NOMO1 NOMO2 NOMO3

1.42e-04131523IPR014766
Domain-

NOMO1 NOMO2 NOMO3

1.42e-041315232.60.40.1120
DomainEGF_Lam

STAB2 LAMA4 CELSR2 USH2A

1.81e-04351524SM00180
DomainPRPP_SYNTHASE

PRPS1L1 PRPS1

1.96e-0431522PS00114
DomainMyxo_disulph_rpt

PAPPA2 PAPPA

1.96e-0431522IPR011936
DomainPRib_PP_synth_CS

PRPS1L1 PRPS1

1.96e-0431522IPR000842
DomainVWFC_1

VWF MUC5B MUC2 MUC5AC

2.03e-04361524PS01208
DomainBROMODOMAIN_1

BRPF3 CECR2 KAT2A BRPF1

2.26e-04371524PS00633
DomainBromodomain

BRPF3 CECR2 KAT2A BRPF1

2.51e-04381524PF00439
DomainVWFC_2

VWF MUC5B MUC2 MUC5AC

2.51e-04381524PS50184
DomainVWC

VWF MUC5B MUC2 MUC5AC

2.51e-04381524SM00214
DomainLAM_G_DOMAIN

FAT3 LAMA4 CELSR2 USH2A

2.51e-04381524PS50025
DomainLaminin_EGF

STAB2 LAMA4 CELSR2 USH2A

2.51e-04381524IPR002049
DomainLaminin_G_2

FAT3 LAMA4 CELSR2 USH2A

3.07e-04401524PF02210
DomainBROMODOMAIN_2

BRPF3 CECR2 KAT2A BRPF1

3.38e-04411524PS50014
DomainBromodomain

BRPF3 CECR2 KAT2A BRPF1

3.71e-04421524IPR001487
DomainVWF_dom

VWF MUC5B MUC2 MUC5AC

3.71e-04421524IPR001007
DomainBROMO

BRPF3 CECR2 KAT2A BRPF1

3.71e-04421524SM00297
Domain-

BRPF3 CECR2 KAT2A BRPF1

3.71e-044215241.20.920.10
DomainLamG

FAT3 LAMA4 CELSR2 USH2A

4.44e-04441524SM00282
DomainEGF_CA

STAB2 FAT3 NOTCH2NLA NOTCH2NLC LRP1B CELSR2

4.90e-041221526SM00179
DomainEGF-like_Ca-bd_dom

STAB2 FAT3 NOTCH2NLA NOTCH2NLC LRP1B CELSR2

5.34e-041241526IPR001881
DomainEGF

STAB2 NOTCH2NLA BCAN NOTCH2NLC LRP1B CELSR2

5.81e-041261526PF00008
DomainPribosyltran_N

PRPS1L1 PRPS1

6.47e-0451522PF13793
DomainPribosyl_synth

PRPS1L1 PRPS1

6.47e-0451522PF14572
DomainRib-P_diPkinase

PRPS1L1 PRPS1

6.47e-0451522IPR005946
DomainPribosyltran_N

PRPS1L1 PRPS1

6.47e-0451522IPR029099
DomainEGF

STAB2 FAT3 NOTCH2NLA LAMA4 BCAN NOTCH2NLC LRP1B CELSR2

6.91e-042351528SM00181
DomainFN3

PAPPA2 FN1 DSCAM AXL ITGB4 LRRN3 USH2A

8.08e-041851527SM00060
DomainEGF-like_dom

STAB2 FAT3 NOTCH2NLA LAMA4 BCAN NOTCH2NLC LRP1B CELSR2

1.01e-032491528IPR000742
DomainLaminin_G

FAT3 LAMA4 CELSR2 USH2A

1.27e-03581524IPR001791
DomainNotch_dom

PAPPA2 PAPPA

1.35e-0371522IPR000800
DomainNotch

PAPPA2 PAPPA

1.35e-0371522PF00066
DomainNL

PAPPA2 PAPPA

1.35e-0371522SM00004
DomainASX_HYDROXYL

FAT3 NOTCH2NLA NOTCH2NLC LRP1B CELSR2

1.35e-031001525PS00010
DomainVWC

VWF MUC5B MUC5AC

1.49e-03281523PF00093
DomainEGF_2

STAB2 FAT3 NOTCH2NLA BCAN NOTCH2NLC LRP1B ITGB4 CELSR2

1.49e-032651528PS01186
DomainFN3_dom

PAPPA2 FN1 DSCAM AXL ITGB4 LRRN3 USH2A

1.64e-032091527IPR003961
DomainTSP_1

CILP ADAMTS1 ADGRB2 SEMA5A

1.73e-03631524PF00090
DomainEGF-type_Asp/Asn_hydroxyl_site

FAT3 NOTCH2NLA NOTCH2NLC LRP1B CELSR2

1.75e-031061525IPR000152
DomainEPL1

BRPF3 BRPF1

1.78e-0381522PF10513
DomainEnhancer_polycomb-like_N

BRPF3 BRPF1

1.78e-0381522IPR019542
DomainTSP1

CILP ADAMTS1 ADGRB2 SEMA5A

1.94e-03651524SM00209
DomainTSP1_rpt

CILP ADAMTS1 ADGRB2 SEMA5A

1.94e-03651524IPR000884
DomainTSP1

CILP ADAMTS1 ADGRB2 SEMA5A

1.94e-03651524PS50092
Domainfn3

FN1 DSCAM AXL ITGB4 LRRN3 USH2A

2.13e-031621526PF00041
DomainKelch_1

RABEPK KLHL38 KLHL21 KBTBD11

2.55e-03701524PF01344
DomainKelch_1

RABEPK KLHL38 KLHL21 KBTBD11

2.55e-03701524IPR006652
DomainGal_Oxidase_b-propeller

RABEPK KLHL21 KBTBD11

2.63e-03341523IPR015916
DomainDUF4939

RTL10 RTL1

2.84e-03101522IPR032549
DomainDUF4939

RTL10 RTL1

2.84e-03101522PF16297
DomainLaminin_EGF

LAMA4 CELSR2 USH2A

2.86e-03351523PF00053
DomainEGF_3

STAB2 FAT3 NOTCH2NLA BCAN NOTCH2NLC LRP1B CELSR2

3.16e-032351527PS50026
DomainLDOC1-rel

RTL10 RTL1

3.45e-03111522IPR032567
DomainPribosyltran

PRPS1L1 PRPS1

3.45e-03111522PF00156
DomainGAIN_dom_N

ADGRB2 CELSR2

3.45e-03111522IPR032471
DomainGAIN

ADGRB2 CELSR2

3.45e-03111522PF16489
DomainABC_A

ABCA1 ABCA13

4.12e-03121522IPR026082
DomainPRTase-like

PRPS1L1 PRPS1

4.12e-03121522IPR029057
DomainPRibTrfase_dom

PRPS1L1 PRPS1

4.12e-03121522IPR000836
Domain-

PRPS1L1 PRPS1

4.12e-031215223.40.50.2020
DomainIg_I-set

DSCAM CILP AXL HEPACAM2 LRIG3 LRRN3

4.66e-031901526IPR013098
PathwayREACTOME_O_LINKED_GLYCOSYLATION

B3GNT9 ADAMTS1 SEMA5A MUC5B B4GALT5 MUC2 MUC5AC

1.21e-051091007MM15164
PathwayREACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS

B3GNT9 MUC5B B4GALT5 MUC2 MUC5AC

6.51e-05601005MM15636
PathwayREACTOME_O_LINKED_GLYCOSYLATION

B3GNT9 ADAMTS1 SEMA5A MUC5B B4GALT5 MUC5AC

1.36e-041111006M27416
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

AKAP6 BRPF3 SASH1 CECR2 RTN4 HECTD4 DIDO1 SCRN1 ZFYVE28 LRIG3 KLHL21 AP5Z1 DHCR24 KBTBD11 BSN

2.42e-085291591514621295
Pubmed

Recurrent NOMO1 Gene Deletion Is a Potential Clinical Marker in Early-Onset Colorectal Cancer and Is Involved in the Regulation of Cell Migration.

NOMO1 NOMO2 NOMO3

9.38e-083159336011023
Pubmed

Mucin gene polymorphisms in otitis media patients.

MUC5B MUC2 MUC5AC

9.38e-083159319718741
Pubmed

Silencing of nodal modulator 1 inhibits the differentiation of P19 cells into cardiomyocytes.

NOMO1 NOMO2 NOMO3

9.38e-083159325576386
Pubmed

Increased expression of MUC5AC and MUC5B promoting bacterial biofilm formation in chronic rhinosinusitis patients.

MUC5B MUC2 MUC5AC

3.74e-074159325638393
Pubmed

Expression of MUC1, MUC2, MUC5AC and MUC5B in mucinous lesions of the breast.

MUC5B MUC2 MUC5AC

3.74e-074159322269464
Pubmed

Munc13-2-/- baseline secretion defect reveals source of oligomeric mucins in mouse airways.

UNC13B MUC5B MUC5AC

3.74e-074159318258655
Pubmed

Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.

MUC5B MUC2 MUC5AC

3.74e-074159323807779
Pubmed

Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.

MUC5B MUC2 MUC5AC

3.74e-074159317471237
Pubmed

The mouse secreted gel-forming mucin gene cluster.

MUC5B MUC2 MUC5AC

3.74e-074159314984930
Pubmed

Establishment of a conditional Nomo1 mouse model by CRISPR/Cas9 technology.

NOMO1 NOMO2 NOMO3

3.74e-074159331833031
Pubmed

Effects of the Helicobacter pylori Virulence Factor CagA and Ammonium Ion on Mucins in AGS Cells.

MUC5B MUC2 MUC5AC

3.74e-074159329869461
Pubmed

Characterization of mouse muc6 and evidence of conservation of the gel-forming mucin gene cluster between human and mouse.

MUC5B MUC2 MUC5AC

3.74e-074159312676567
Pubmed

A locus for autosomal recessive pseudoxanthoma elasticum, with penetrance of vascular symptoms in carriers, maps to chromosome 16p13.1.

NOMO1 NOMO2 NOMO3

3.74e-07415939267806
Pubmed

Polymorphism of human mucin genes in chest disease: possible significance of MUC2.

MUC5B MUC2 MUC5AC

9.31e-075159311062147
Pubmed

Differential expression of MUC genes in endometrial and cervical tissues and tumors.

MUC5B MUC2 MUC5AC

9.31e-075159316188033
Pubmed

Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.

MUC5B MUC2 MUC5AC

1.86e-066159319110483
Pubmed

Nicalin and its binding partner Nomo are novel Nodal signaling antagonists.

NOMO1 NOMO2 NOMO3

5.16e-068159315257293
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

AKAP6 UNC13B SOX10 VWF FN1 DSCAM MYCBP2 ADAMTS1 UBR4 HECTD4 RTL10 ADARB1 LRP1B GSK3A RHOG UBA7 NOMO2 LGI3 USP54

7.15e-0612851591935914814
Pubmed

Substrate-driven assembly of a translocon for multipass membrane proteins.

NOMO1 NOMO2 NOMO3

7.72e-069159336261522
Pubmed

An ER translocon for multi-pass membrane protein biogenesis.

NOMO1 NOMO2 NOMO3

1.51e-0511159332820719
Pubmed

Functional proteomics mapping of a human signaling pathway.

PAPPA2 VWF FN1 SASH1 MYCBP2 UBR4 LAMA4 DENND2B NOMO1 GRIP1 PAPPA NOMO3

1.92e-055911591215231748
Pubmed

Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5).

MUC5B MUC5AC

2.08e-05215927513696
Pubmed

The association between MUC5AC and MUC5B genes expression and remodeling progression in severe neutrophilic asthma: A direct relationship.

MUC5B MUC5AC

2.08e-052159237146737
Pubmed

MUC5AC and MUC5B Mucins Are Decreased in Cystic Fibrosis Airway Secretions.

MUC5B MUC5AC

2.08e-052159214988081
Pubmed

Mucin glycosylation changes in cystic fibrosis lung disease are not manifest in submucosal gland secretions.

MUC5B MUC5AC

2.08e-052159215563276
Pubmed

The expression of MUC5AC and MUC5B mucin genes in the mucosa of chronic rhinosinusitis and nasal polyposis.

MUC5B MUC5AC

2.08e-052159217621824
Pubmed

Muc5b is required for airway defence.

MUC5B MUC5AC

2.08e-052159224317696
Pubmed

Macrophages are related to goblet cell hyperplasia and induce MUC5B but not MUC5AC in human bronchus epithelial cells.

MUC5B MUC5AC

2.08e-052159222391959
Pubmed

Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules.

MUC5B MUC5AC

2.08e-052159235776514
Pubmed

The ocular surface phenotype of Muc5ac and Muc5b null mice.

MUC5B MUC5AC

2.08e-052159224327612
Pubmed

Chlorination and oxidation of human plasma fibronectin by myeloperoxidase-derived oxidants, and its consequences for smooth muscle cell function.

MPO FN1

2.08e-052159230237127
Pubmed

Pregnancy-associated plasma protein-A2 (PAPP-A2): tissue expression and biological consequences of gene knockout in mice.

PAPPA2 PAPPA

2.08e-052159221586553
Pubmed

Gel-forming mucins form distinct morphologic structures in airways.

MUC5B MUC5AC

2.08e-052159228607090
Pubmed

Mucolytic activity of bacterial and human chitinases.

MUC2 MUC5AC

2.08e-052159217321686
Pubmed

Muc5b is mainly expressed and sialylated in the nasal olfactory epithelium whereas Muc5ac is exclusively expressed and fucosylated in the nasal respiratory epithelium.

MUC5B MUC5AC

2.08e-052159231030254
Pubmed

Altered expression of MUC2 and MUC5AC in progression of colorectal carcinoma.

MUC2 MUC5AC

2.08e-052159220731025
Pubmed

The idiopathic pulmonary fibrosis honeycomb cyst contains a mucocilary pseudostratified epithelium.

MUC5B MUC5AC

2.08e-052159223527003
Pubmed

Role of FN1 and GREB1 gene polymorphisms in endometriosis.

FN1 GREB1

2.08e-052159231115525
Pubmed

Modeling ADAMTS13-von Willebrand factor interaction: Implications for oxidative stress-related cardiovascular diseases and type 2A von Willebrand disease.

VWF ADAMTS1

2.08e-052159221937160
Pubmed

Up-regulation of MUC5AC and MUC5B mucin genes in nasopharyngeal respiratory mucosa and selective up-regulation of MUC5B in middle ear in pediatric otitis media with effusion.

MUC5B MUC5AC

2.08e-052159216540890
Pubmed

Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma.

MUC5B MUC5AC

2.08e-052159227845589
Pubmed

TLR3 signaling is downregulated by a MAVS isoform in epithelial cells.

MAVS TLR3

2.08e-052159227593154
Pubmed

Co-Mutation of FAT3 and LRP1B in Lung Adenocarcinoma Defines a Unique Subset Correlated With the Efficacy of Immunotherapy.

FAT3 LRP1B

2.08e-052159235069585
Pubmed

Loss of CSMD1 or 2 may contribute to the poor prognosis of colorectal cancer patients.

CSMD2 CSMD1

2.08e-052159224408017
Pubmed

Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease.

MUC5B MUC5AC

2.08e-052159227435107
Pubmed

Mucins MUC5B and MUC5AC in Distal Airways and Honeycomb Spaces: Comparison among Idiopathic Pulmonary Fibrosis/Usual Interstitial Pneumonia, Fibrotic Nonspecific Interstitial Pneumonitis, and Control Lungs.

MUC5B MUC5AC

2.08e-052159226871672
Pubmed

Studies of mucus in mouse stomach, small intestine, and colon. II. Gastrointestinal mucus proteome reveals Muc2 and Muc5ac accompanied by a set of core proteins.

MUC2 MUC5AC

2.08e-052159223832517
Pubmed

Studies of mucus in mouse stomach, small intestine, and colon. III. Gastrointestinal Muc5ac and Muc2 mucin O-glycan patterns reveal a regiospecific distribution.

MUC2 MUC5AC

2.08e-052159223832516
Pubmed

Antitumor immunity and prognosis value elicited by FAT3 and LRP1B co-mutation in endometrial cancer.

FAT3 LRP1B

2.08e-052159238696842
Pubmed

In silico cloning of mouse Muc5b gene and upregulation of its expression in mouse asthma model.

MUC5B MUC5AC

2.08e-052159211587997
Pubmed

Mutational analysis of the proteolytic domain of pregnancy-associated plasma protein-A (PAPP-A): classification as a metzincin.

PAPPA2 PAPPA

2.08e-052159211513734
Pubmed

Pathophysiological relevance of sputum MUC5AC and MUC5B levels in patients with mild asthma.

MUC5B MUC5AC

2.08e-052159234656442
Pubmed

Intestinal MUC2 and gastric M1/MUC5AC in preneoplastic lesions induced by 1,2-dimethylhydrazine in rat: a sequential analysis.

MUC2 MUC5AC

2.08e-052159217203232
Pubmed

Distinctly regulated functions and mobilization of CD11c-positive cells elicited by TLR3- and IPS-1 signaling in the cornea.

MAVS TLR3

2.08e-052159230571996
Pubmed

Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.

MUC5B MUC5AC

2.08e-052159234058148
Pubmed

C-Mannosylation of MUC5AC and MUC5B Cys subdomains.

MUC5B MUC5AC

2.08e-052159214718370
Pubmed

Methylation status of promoters and expression of MUC2 and MUC5AC mucins in pancreatic cancer cells.

MUC2 MUC5AC

2.08e-052159212527922
Pubmed

Mucin production during prenatal and postnatal murine lung development.

MUC5B MUC5AC

2.08e-052159221653907
Pubmed

The complete cDNA sequence and structural polymorphism of the polypeptide chain of porcine submaxillary mucin.

VWF MUC2

2.08e-05215929407109
Pubmed

MUC5B mobilizes and MUC5AC spatially aligns mucociliary transport on human airway epithelium.

MUC5B MUC5AC

2.08e-052159236427316
Pubmed

Oncolytic Reovirus Inhibits Immunosuppressive Activity of Myeloid-Derived Suppressor Cells in a TLR3-Dependent Manner.

MAVS TLR3

2.08e-052159229555782
Pubmed

Pregnancy associated plasma protein-A as a prognostic biomarker of all-cause mortality and cardiovascular events in patients presenting with chest pain: a systematic review.

PAPPA2 PAPPA

2.08e-052159229144175
Pubmed

Mucin deficiency causes functional and structural changes of the ocular surface.

MUC5B MUC5AC

2.08e-052159223272068
Pubmed

Younger patients with COME are more likely to have mucoid middle ear fluid containing mucin MUC5B.

MUC5B MUC5AC

2.08e-052159227729120
Pubmed

A genetic association study of CSMD1 and CSMD2 with cognitive function.

CSMD2 CSMD1

2.08e-052159227890662
Pubmed

De novo NUF2 variant in a novel inherited bone marrow failure syndrome including microcephaly and renal hypoplasia.

MUC5B MUC5AC

2.08e-052159236111525
Pubmed

In vivo glycosylation of mucin tandem repeats.

MUC2 MUC5AC

2.08e-052159211445551
Pubmed

The complement control-related genes CSMD1 and CSMD2 associate to schizophrenia.

CSMD2 CSMD1

2.08e-052159221439553
Pubmed

TRIM47-CDO1 axis dictates hepatocellular carcinoma progression by modulating ferroptotic cell death through the ubiquitin‒proteasome system.

CDO1 TRIM47

2.08e-052159238614226
Pubmed

[Interleukin-1beta induces MUC2/MUC5B gene expression in human nasal epithelial cells].

MUC5B MUC2

2.08e-052159220873538
Pubmed

Temporal analysis of goblet cells and mucin gene expression in murine models of allergic asthma.

MUC2 MUC5AC

2.08e-052159214594655
Pubmed

Normal murine respiratory tract has its mucus concentrated in clouds based on the Muc5b mucin.

MUC5B MUC5AC

2.08e-052159232348677
Pubmed

Reassessment of the importance of mucins in determining sputum properties in cystic fibrosis.

MUC5B MUC5AC

2.08e-052159224332705
Pubmed

Defective Angiogenesis and Intraretinal Bleeding in Mouse Models With Disrupted Inner Retinal Lamination.

DSCAM FAT3

2.08e-052159227046121
Pubmed

Abnormal subcellular distribution of mature MUC2 and de novo MUC5AC mucins in adenomas of the rectum: immunohistochemical detection using non-VNTR antibodies to MUC2 and MUC5AC peptide.

MUC2 MUC5AC

2.08e-052159212820724
Pubmed

Plasma fibronectin supports hemostasis and regulates thrombosis.

VWF FN1

2.08e-052159225180602
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

SOX10 B3GNT9 FBXW10 RPS6KA5 KAT2A LRP1B GSK3A RHOG DNASE2B TRPM3 PCSK4 WNK3 PRPS1

3.37e-057301591334857952
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

VWF FN1 MYCBP2 DBF4B NOTCH2NLA ADGRB2 MBIP NOMO1 HOXA1 GRIP1 CCAR2

5.79e-055601591121653829
Pubmed

Common fragile sites (CFS) and extremely large CFS genes are targets for human papillomavirus integrations and chromosome rearrangements in oropharyngeal squamous cell carcinoma.

LRP1B CSMD1

6.21e-053159227636103
Pubmed

Identification of two new members of the CSMD gene family.

CSMD2 CSMD1

6.21e-053159212906867
Pubmed

High-Mobility Group Box 1 Upregulates MUC5AC and MUC5B Expression in Primary Airway Epithelial Cells.

MUC5B MUC5AC

6.21e-053159229286856
Pubmed

Promoter regions of the human X-linked housekeeping genes PRPS1 and PRPS2 encoding phosphoribosylpyrophosphate synthetase subunit I and II isoforms.

PRPS1L1 PRPS1

6.21e-05315921314091
Pubmed

Nebulized Menthol Impairs Mucociliary Clearance via TRPM8 and MUC5AC/MUC5B in Primary Airway Epithelial Cells.

MUC5B MUC5AC

6.21e-053159236675209
Pubmed

Differences in the expression of mucins in various forms of cystitis glandularis.

MUC2 MUC5AC

6.21e-053159217659847
Pubmed

Immune Sensing of Aeroallergen-Associated Double-Stranded RNA Triggers an IFN Response and Modulates Type 2 Lung Inflammation.

MAVS TLR3

6.21e-053159231562213
Pubmed

Th2 cytokines orchestrate the secretion of MUC5AC and MUC5B in IL-5-positive chronic rhinosinusitis with nasal polyps.

MUC5B MUC5AC

6.21e-053159229802623
Pubmed

Down regulation of TRIF, TLR3, and MAVS in HCV infected liver correlates with the outcome of infection.

MAVS TLR3

6.21e-053159228480979
Pubmed

Sensing and signaling of immunogenic extracellular RNAs restrain group 2 innate lymphoid cell-driven acute lung inflammation and airway hyperresponsiveness.

MAVS TLR3

6.21e-053159232730309
Pubmed

Poly(A)-specific ribonuclease and Nocturnin in squamous cell lung cancer: prognostic value and impact on gene expression.

PARN NOCT

6.21e-053159226541675
Pubmed

3β-hydroxysteroid-Δ24 reductase dampens anti-viral innate immune responses by targeting K27 ubiquitination of MAVS and STING.

MAVS DHCR24

6.21e-053159238032198
Pubmed

Cadherin-catenin adhesion system and mucin expression: a comparison between young and older patients with gastric carcinoma.

MUC2 MUC5AC

6.21e-053159218825309
Pubmed

Platelets, inflammatory cells, von Willebrand factor, syndecan-1, fibrin, fibronectin, and bacteria co-localize in the liver thrombi of Bacillus anthracis-infected mice.

VWF FN1

6.21e-053159222001909
Pubmed

Haplotype-specific modulation of a SOX10/CREB response element at the Charcot-Marie-Tooth disease type 4C locus SH3TC2.

SOX10 SH3TC2

6.21e-053159224833716
Pubmed

Investigation of the impact of AXL, TLR3, and STAT2 in congenital Zika syndrome through genetic polymorphisms and protein-protein interaction network analyses.

AXL TLR3

6.21e-053159237526179
Pubmed

Adenomatous and foveolar gastric dysplasia: distinct patterns of mucin expression and background intestinal metaplasia.

MUC2 MUC5AC

6.21e-053159218300795
Pubmed

Resistin upregulates MUC5AC/B mucin gene expression in human airway epithelial cells.

MUC5B MUC5AC

6.21e-053159229604272
Pubmed

Differential outcome of TRIF-mediated signaling in TLR4 and TLR3 induced DC maturation.

MAVS TLR3

6.21e-053159226508631
Pubmed

Expression of aberrant mucins in lobular carcinoma with histiocytoid feature of the breast.

MUC2 MUC5AC

6.21e-053159217333267
Pubmed

Liver stroma enhances activation of TLR3-triggered NK cells through fibronectin.

FN1 TLR3

6.21e-053159218384880
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

PAPPA2 BCAN CSMD2 CR1 PAPPA CSMD1

7.11e-075710061179
GeneFamilyPappalysins|Sushi domain containing

PAPPA2 PAPPA

3.03e-0521002897
GeneFamilyCD molecules|Mucins

MUC5B MUC2 MUC5AC

2.03e-04211003648
GeneFamilyFibronectin type III domain containing

FN1 DSCAM AXL ITGB4 LRRN3 USH2A

2.63e-041601006555
GeneFamilyATAC complex

KAT2A MBIP

2.27e-031310021058
GeneFamilyATP binding cassette subfamily A

ABCA1 ABCA13

2.64e-03141002805
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

AKAP6 DSCAM MYCBP2 RTN4 TTC14 CSMD2 LRP1B GRIP1 TBC1D32 LRRN3 PPP2R3A PIEZO2 BLCAP GPR158 PLXNC1 KBTBD11 PAPPA CSMD1 BSN MUC2 WNK3

2.99e-06110615721M39071
CoexpressionPEREZ_TP53_TARGETS

ABCA1 CILP ABCA13 INPP5B HECTD4 RTL10 DIDO1 ZFYVE28 UNC119 BLCAP CELSR2 KLHL21 BRPF1 TLR3 ZNF398 GREB1 NOCT MUC2 MUC5AC DISP1 VPS13B CREB3L2

3.04e-06120115722M4391
CoexpressionGAO_ESOPHAGUS_25W_C4_FGFR1HIGH_EPITHELIAL_CELLS

SH3TC2 CILP ADAMTS1 ACP3 ADGRB2 NOMO1 PLXNC1 KLHL21 ERMARD

4.82e-062081579M39139
CoexpressionAtlasdev gonad_e12.5_M_SertoliCell_Sox9_top-relative-expression-ranked_500

UNC13B CDO1 SH3TC2 BRPF3 AXL LAMA4 SCRN1 SEMA5A DENND2B UNC119 PLXNC1 TRIM47 WNK3 CREB3L2

3.11e-0644115014gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_500
ToppCellControl-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

CDO1 SH3TC2 VWF RPS6KA5 ADAMTS1 LRP1B NOMO1 NOMO2 CSMD1 NOMO3

1.62e-09192156107e89b9125e8b85f6be85eeccef5c8644647ab0e1
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 ABCA13 FAT3 MUC5B LRP1B PIEZO2 TRPM3 CSMD1 USH2A

1.87e-0818415692cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 ABCA13 FAT3 MUC5B LRP1B PIEZO2 TRPM3 CSMD1 USH2A

1.87e-081841569ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 ABCA13 FAT3 MUC5B LRP1B PIEZO2 TRPM3 CSMD1 USH2A

1.87e-0818415692b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell10x5'-Liver-Myeloid_Mac-Intestinal_macrophages|Liver / Manually curated celltypes from each tissue

ABCA1 SASH1 PARD3B CR1 LRP1B GRIP1 LRIG3 PIEZO2

8.19e-0815615689a897fc79c4fae94c5f2e9012d65297f9225e5e3
ToppCelldroplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPIB DSCAM ETV3 IDI2 GRPR RNF43 STAT4 PLXNC1

2.16e-0717715684672cc75225a4a23b298afa8ce439628262519db
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PAPPA2 B3GNT9 CECR2 SEMA5A DENND2B PIEZO2 GPR158 PAPPA

2.36e-071791568a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDO1 FN1 ADAMTS1 FAT3 LAMA4 ADARB1 LRRN3 PIEZO2

4.52e-0719515684243190ad291d56694e2155954dbaa879c9d3844
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDO1 FN1 ADAMTS1 FAT3 LAMA4 ADARB1 LRRN3 PIEZO2

4.70e-0719615689737a5f006d37b549f281e1863aca558e1e4dc99
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDO1 FN1 ADAMTS1 FAT3 LAMA4 ADARB1 LRRN3 PIEZO2

4.70e-071961568cecf82cd5e0a3835d655f5e7478578674a63ce25
ToppCellControl_saline-Epithelial_alveolar-AT_2-Differentiating_AT2|Control_saline / Treatment groups by lineage, cell group, cell type

UNC13B ELAPOR2 CECR2 TTC14 MBIP RNF43 LGI3 USP54

4.88e-07197156844a59dfb889577b3160a5b13ada1276771a00241
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CDO1 FN1 ADAMTS1 FAT3 LAMA4 ADARB1 LRRN3 PIEZO2

5.07e-071981568f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CDO1 FN1 ADAMTS1 FAT3 LAMA4 ADARB1 LRRN3 PIEZO2

5.27e-07199156866a79732caf2f04c09b4d9832377aa01ca477677
ToppCellControl_saline-Endothelial-Endothelial-Artery|Control_saline / Treatment groups by lineage, cell group, cell type

VWF FN1 RPS6KA5 ADAMTS1 ITGB4 GRPR USP54 TRIM47

5.47e-07200156865b71f1e8da5c3750fcd0a2e66d9ef3125a3f78a
ToppCellfacs-Marrow-Granulocytes-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3TC2 BRPF3 STAB2 FN1 SASH1 PRPS1L1 MAVS

1.57e-06160156756e6f4b82b5dc41c45f9d253c2db314a6f702b84
ToppCellfacs-Marrow-Granulocytes-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3TC2 BRPF3 STAB2 FN1 SASH1 PRPS1L1 MAVS

1.57e-061601567bb1b966fb9e801db15e67d03e49db4609d6f935a
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Microglia/Mac|Myeloid_cells / Location, Cell class and cell subclass

UNC13B ZNF862 ETV3 HOXA1 LRIG3 MUC5AC DISP1

2.27e-061691567dba8f5599aa21feef5b7fdfed2e3ab54748d80f7
ToppCelldroplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ETV3 HEPACAM2 IDI2 WDFY4 GRPR PLXNC1 TLR3

2.27e-061691567b2d53159e344fad6fcdc485d5b8f6cf1bf094b1f
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AXL FAT3 HECTD4 LRP1B DENND2B PLXNC1 PAPPA

2.36e-0617015675570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Microglia/Mac|metastatic_Lymph_Node / Location, Cell class and cell subclass

UNC13B ABCA1 ZNF862 ETV3 HOXA1 MUC5AC DISP1

2.55e-061721567f673a2e697b46e7cfa4186cb3fb2b98e3c83703e
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast-myofibroblast_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PAPPA2 ZC3H14 SEC24A B4GALT5 TBC1D32 UBA7 FAM117A

2.75e-061741567eb8012823b08729b462d1e5212f4873bb6b4eb1e
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PAPPA2 ZC3H14 SEC24A B4GALT5 TBC1D32 UBA7 FAM117A

2.75e-06174156732fdeeebeeeca657eac6329caad4c28ca54e4d1c
ToppCellASK428-Immune-B_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

SPIB DBF4B SCRN1 ADARB1 RITA1 USP54 CSMD1

2.86e-061751567e0979e5795a49b4e5c9b88e7fe6b7bda7a413a6c
ToppCellfacs-Marrow-B-cells-3m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX10 BCAN LRIG3 LGI3 TLR3 CCAR2 MPPED1

3.44e-061801567c54af6fb11484dacd3efa1f10a487376ff820a5e
ToppCellfacs-Marrow-B-cells-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX10 BCAN LRIG3 LGI3 TLR3 CCAR2 MPPED1

3.44e-06180156707ac979b21be2425294d9818c48b5a1e6f014c19
ToppCelldroplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3TC2 STAB2 LAMA4 PARD3B ADARB1 LRIG3 PLXNC1

3.57e-061811567a53f05c4c47465ee62e353716456bd09ab464b23
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ABCA1 FN1 ADAMTS1 FAT3 LAMA4 PIEZO2 PAPPA

5.08e-06191156708720998aa55131d7377c4c67c4c935865bd7d79
ToppCellCOPD-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

SH3TC2 VWF ADAMTS1 NOMO1 NOMO2 CSMD1 NOMO3

5.08e-061911567ef16ad1c1cd2c0c0377957398c98775b62a81754
ToppCell10x5'v1-week_17-19-Endothelial-stroma-proliferating_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

STAB2 VWF SASH1 LAMA4 LRIG3 PIEZO2 BSN

5.08e-061911567dc9e5eb6aa31b8d79aeec33e59b9138dfb469a3b
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS1 FAT3 LAMA4 SEMA5A ADARB1 PIEZO2 PAPPA

5.26e-061921567162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FN1 ADAMTS1 FAT3 LAMA4 SEMA5A ADARB1 PIEZO2

5.26e-0619215673d0cb19f037f604253d7d728689aeaa94251e92b
ToppCellCOPD-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

FN1 CECR2 FAT3 LAMA4 ADARB1 LRRN3 PIEZO2

5.26e-06192156762904f94dfce430456f05066522cbf9bd29f4d7e
ToppCellLPS-antiTNF-Stromal_mesenchymal|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FN1 ADAMTS1 FAT3 LAMA4 SEMA5A ADARB1 PIEZO2

5.63e-0619415676e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCell21-Trachea-Mesenchymal|Trachea / Age, Tissue, Lineage and Cell class

CDO1 FN1 ADAMTS1 FAT3 AKNAD1 LAMA4 PIEZO2

5.63e-061941567749dd8113ef260e00facac09de9861d61725124a
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDO1 FN1 FAT3 LAMA4 ADARB1 LRRN3 PIEZO2

5.82e-061951567df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

UNC13B ELAPOR2 CECR2 MBIP LGI3 DHCR24 USP54

6.02e-0619615677e5addaa844e66f8160e05858c341866a80aed23
ToppCellPBMC-Control-cDC_3|Control / Compartment, Disease Groups and Clusters

DIDO1 SCRN1 WDFY4 NOMO1 GRIP1 PLXNC1 DCAF7

6.02e-06196156709d197b321ff9f13c0672ea059c850845b0dbbd5
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

UNC13B ELAPOR2 MBIP RNF43 LGI3 DHCR24 USP54

6.22e-0619715671485933986921ff45669d9b7501c8d17050b3e97
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

UNC13B ELAPOR2 ADAMTS1 CECR2 MBIP LGI3 USP54

6.22e-061971567bf10727fbe90b71d2ac60a11711e5f0701b3799d
ToppCellCOVID-19-Fibroblasts|COVID-19 / group, cell type (main and fine annotations)

FN1 LAMA4 PARD3B CSMD2 ADARB1 PIEZO2 PAPPA

6.22e-061971567fb847f2277609c31fffcdf49517243ce0684facf
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDO1 FN1 FAT3 LAMA4 ADARB1 LRRN3 PIEZO2

6.22e-06197156713896ec65ccda0b928c91d41112dc01b480036b7
ToppCelldistal-1-Endothelial-Lymphatic|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MPO STAB2 AKNAD1 LAMA4 PIEZO2 SLC13A4 KBTBD11

6.43e-061981567b6fea363463c8dd7e6780c085ece4900266a6286
ToppCellproximal-mesenchymal-Alveolar_Fibroblast|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CDO1 FN1 FAT3 LAMA4 ADARB1 LRRN3 PIEZO2

6.65e-0619915677f4840ae6a888380feca722543e5e52783f3e35d
ToppCellproximal-3-mesenchymal-Alveolar_Fibroblast|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CDO1 FN1 FAT3 LAMA4 ADARB1 LRRN3 PIEZO2

6.65e-061991567301d02bbb37e6f1d24b6e865bc3fe3e91260eb30
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SOX10 DSCAM SEMA5A BCAN CSMD2 LRP1B CSMD1

6.65e-061991567333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCellproximal-mesenchymal-Alveolar_Fibroblast-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CDO1 FN1 FAT3 LAMA4 ADARB1 LRRN3 PIEZO2

6.65e-0619915679a16e519fb0651a7c4d8e05b931df4fb3b0eb3d1
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ABCA1 FN1 MYCBP2 ADAMTS1 LAMA4 SEMA5A ADARB1

6.65e-061991567a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SOX10 DSCAM SEMA5A CSMD2 LRP1B CSMD1 WNK3

6.65e-06199156719a97e27a4758e794ce7246d295e112b47931a48
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SOX10 DSCAM SEMA5A BCAN CSMD2 LRP1B CSMD1

6.65e-061991567e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

RABEPK ELAPOR2 CCNJ MBIP RNF43 USP54 WNK3

6.65e-061991567121de4e02585de3a3010398387c523bacf8ce546
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

MAGEB2 DSCAM ABCA13 CSMD2 CSMD1 USH2A

1.28e-051461566c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCellE15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

VWF FN1 HOXA1 RTL1 PLXNC1 MUC2

1.74e-051541566e65e4636646164610f33f7bbac0d879a3ea55986
ToppCellControl-Endothelial-Epi-like|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RABEPK CNOT11 INPP5B MBIP RNF43 RITA1

1.94e-0515715664d02c50d5d1b892ea241e98724386d8a5a156a46
ToppCellControl-Endothelial-Epi-like-Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RABEPK CNOT11 INPP5B MBIP RNF43 RITA1

1.94e-0515715662c369660c752c0fb3bd798a561d3359e2f9aa983
ToppCellsevere_COVID-19-pDC|World / disease group, cell group and cell class (v2)

B3GNT9 SPIB TIFAB AXL NOMO1 PPP2R3A

2.08e-051591566e1c48c4ceda116826819ff9adeed7bad6a58844d
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

DSCAM FAT3 CSMD2 GPR158 CSMD1 USH2A

2.08e-0515915665335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CECR2 FAT3 MUC5B LRP1B GRIP1 USH2A

2.15e-051601566c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CECR2 FAT3 MUC5B LRP1B GRIP1 USH2A

2.15e-05160156625c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellCerebellum-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Klk6_(Klk6)|Cerebellum / BrainAtlas - Mouse McCarroll V32

SLAMF1 ITGB4 PIEZO2 WDR87 PAPPA

2.23e-05961565a48235df1f5526ce3ffc4c0c2ba038eb20229c55
ToppCellCerebellum-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Klk6_(Klk6)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

SLAMF1 ITGB4 PIEZO2 WDR87 PAPPA

2.23e-059615650fc179af7370a29b7bd5d81e1302a479ae72f196
ToppCellCerebellum-Macroglia-OLIGODENDROCYTE-O2-Trf|Cerebellum / BrainAtlas - Mouse McCarroll V32

SLAMF1 ITGB4 PIEZO2 WDR87 PAPPA

2.23e-05961565c301ecfd67ece8bb12be1b94b614957a58046457
ToppCellCerebellum-Macroglia-OLIGODENDROCYTE-O2|Cerebellum / BrainAtlas - Mouse McCarroll V32

SLAMF1 ITGB4 PIEZO2 WDR87 PAPPA

2.23e-059615657d402d543ff159c9bb84c00b083e6e18fc0ff786
ToppCellP07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CDO1 FN1 ADAMTS1 FAT3 ADARB1 MUC5AC

2.23e-051611566b19f82dd98a3064581793711bb70373f18abecd9
ToppCelldroplet-Lung-LUNG-30m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSCAM ETV3 IDI2 GRPR RNF43 PLXNC1

2.83e-0516815660e8b0e6399c6c82c9c0e546f7316f902de0765d3
ToppCellSigmoid-Macrophage-Macrophage|Macrophage / Region, Cell class and subclass

ABCA1 SASH1 AXL TTC14 ETV3 PLXNC1

2.83e-051681566bb16e135b6ae0d66615420b61edd6f62f2a3233c
ToppCellfacs-Marrow-B-cells-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3TC2 BRPF3 HECTD4 SLC5A2 FAM117A GPR158

2.83e-05168156608fe8fa43c343c03f9a2f0b982192fde04a7c027
ToppCellfacs-Marrow-B-cells-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3TC2 BRPF3 HECTD4 SLC5A2 FAM117A GPR158

2.83e-051681566d4053b2fffb19e0376b8ceb92e87ec4447d96a3e
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA1 FN1 ADAMTS1 LAMA4 RTL1 PAPPA

2.93e-051691566c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCell343B-Myeloid-Dendritic-cDC_activated|343B / Donor, Lineage, Cell class and subclass (all cells)

SPIB TIFAB ETV3 BTN2A2 GPR158 PLXNC1

2.93e-0516915662098f15a388d019ed7f1d4c209affd5ca2886dcc
ToppCellEndothelial-B-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

STAB2 VWF AKNAD1 LAMA4 PIEZO2 KBTBD11

2.93e-0516915668889c9e8af1ab0b093d57b69abd80b59b3461be9
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

UNC13B ABCA1 VWF SEMA5A PARD3B USP54

3.03e-051701566e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell15-Trachea-Mesenchymal-Mesenchyme_RSPO2+|Trachea / Age, Tissue, Lineage and Cell class

CDO1 FN1 ADAMTS1 FAT3 LAMA4 B4GALT5

3.45e-051741566fa0681e91724b9a51ee28b214ea5aa14e62ba1a3
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA1 ADAMTS1 SEMA5A DENND2B PAPPA GREB1

3.45e-051741566f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Endothelial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CECR2 TBC1D32 PLXNC1 LGI3 RITA1 USP54

3.45e-051741566c58328c2f262506a4518f49f148e29874faf9171
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSCAM ETV3 IDI2 GRPR RNF43 PLXNC1

3.56e-05175156691cb819a1786020713b7e64480de0545380daae9
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDO1 SEMA5A BCAN UNC119 CCAR2 CSMD1

3.56e-051751566d67c77eee979ad029e7545f383326f0ff77c6e5f
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Dedifferentiated_Liposarcoma-4|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

ELAPOR2 SASH1 CR1 SESN1 KBTBD11 PAPPA

3.56e-05175156616849ea8f0985108baa2085f34c3de14a4f9f28b
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDO1 SEMA5A BCAN UNC119 CCAR2 CSMD1

3.56e-0517515661d1cdbf3221b03e24eae38afd57cbd6736b37a53
ToppCelldroplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ELAPOR2 STAB2 LAMA4 PRPS1L1 TRPM3 PLXNC1

3.68e-0517615663494ffa8555e6edf4b1250e10434bae9b73ec845
ToppCelldroplet-Liver-Npc-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ELAPOR2 STAB2 LAMA4 PRPS1L1 TRPM3 PLXNC1

3.68e-051761566d43f6b7828b98e1dab7b726a5f99499d65a7db80
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STAB2 VWF SASH1 LAMA4 PIEZO2 KBTBD11

3.80e-051771566b1775e05c28883a15c56628028770bc59d3233fb
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ELAPOR2 ABCA1 TRPM3 GPR158 RTL1 BSN

3.92e-051781566fcbbcc44271515de1969b4732b6441c012693d5f
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

UNC13B DSCAM PARD3B MBIP CELSR2 USP54

4.04e-051791566cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCellP28-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

AKAP6 SOX10 ZFYVE28 PAPPA GREB1 CSMD1

4.17e-0518015661e819c5c87704ec6535dfeaae56561895e239d07
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX10 SLAMF1 ITGB4 PAPPA GREB1 CSMD1

4.17e-051801566d9c9399df3e2d9f23dbbfffb6cbe8404bf01e2b7
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX10 SLAMF1 ITGB4 PAPPA GREB1 CSMD1

4.17e-051801566dad458398683ff80a6e207bdc08e257d1bb757d6
ToppCellControl-Fibroblasts-Airway_smooth_muscle|Control / group, cell type (main and fine annotations)

AKAP6 FN1 ADAMTS1 FAT3 LAMA4 ADARB1

4.17e-051801566d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

STAB2 SASH1 ADAMTS1 LAMA4 PIEZO2 KBTBD11

4.30e-051811566e898ecb8d8f2eb2204225b7b0d665cadcd241139
ToppCell-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

LAMA4 BCAN SLAMF1 PIEZO2 PAPPA WNK3

4.30e-051811566ef579e958f334da0f9415aa7e3d5c02c807954a6
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

FN1 FAT3 LAMA4 ADARB1 LRRN3 PIEZO2

4.30e-0518115669ede19228ba5c0668a9c06c915510b95585216ef
ToppCelldroplet-Marrow-BM-30m-Lymphocytic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GNT9 ABCA1 AXL HEPACAM2 CSMD1 CREB3L2

4.30e-051811566cd46eba2e03fd15d8de8e875793ae2f51fa98b3b
ToppCelldroplet-Marrow-BM-30m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GNT9 ABCA1 AXL HEPACAM2 CSMD1 CREB3L2

4.30e-051811566c7d12c7de227c9433ec2303b8929e957b833f59b
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FN1 ADAMTS1 CECR2 PIEZO2 PAPPA GREB1

4.43e-0518215663dfa9187e9d2bab1d199079d29209c4648220ada
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Nefm_(MGE-derived_cortical_interneurons--basket_cells)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

HEPACAM2 BTN2A2 TEX38 USH2A

4.44e-05561564ac776a6e8d0b5596dc492a05235e518cbfc7b5ed
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Nefm_(MGE-derived_cortical_interneurons--basket_cells)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

HEPACAM2 BTN2A2 TEX38 USH2A

4.44e-055615640417516b9241a756fb2bcd611691c675ca98030d
ToppCelldroplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3TC2 STAB2 LAMA4 PARD3B ADARB1 PLXNC1

4.57e-051831566709a486154b3157427deb3b8886b63ac39ea42dd
ToppCelldroplet-Liver-nan-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3TC2 STAB2 LAMA4 PARD3B ADARB1 PLXNC1

4.57e-051831566dc06f19f6f80f4c7f13f1f990c1fe0f91ba64ea7
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA1 ADAMTS1 LAMA4 KIAA0825 PAPPA GREB1

4.57e-0518315665377b4fbd8fdfe68933b4c0965aa9525f7f31591
ToppCelldroplet-Liver-Npc-21m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX10 SPIB SCRN1 HEPACAM2 PIEZO2 CELSR2

4.57e-05183156699ab7a43527eb226027efbcd8c0b6a8e46fc3c93
ToppCelldroplet-Liver-Npc-21m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX10 SPIB SCRN1 HEPACAM2 PIEZO2 CELSR2

4.57e-05183156628916f0597690ff534578be2cb715b485cb1de1a
Diseasecystitis (is_marker_for)

MUC2 MUC5AC

2.60e-0521512DOID:1679 (is_marker_for)
Diseasevon Willebrand factor measurement, coronary artery disease

STAB2 VWF HECTD4 SEMA5A CELSR2 PMFBP1

3.34e-051181516EFO_0001645, EFO_0004629
Diseasesputum mucin-5B amount

MUC2 MUC5AC

7.78e-0531512OBA_2050332
Diseasemyocardial infarction

PAPPA2 FN1 SASH1 INPP5B HECTD4 ZNF831 DENND2B PPP2R3A CELSR2

8.46e-053501519EFO_0000612
Diseasefactor VIII measurement, Ischemic stroke

STAB2 VWF HECTD4

1.20e-04191513EFO_0004630, HP_0002140
Diseasemucinous adenocarcinoma (is_marker_for)

MUC2 MUC5AC

2.58e-0451512DOID:3030 (is_marker_for)
DiseaseDiffuse interstitial pulmonary fibrosis

MUC5B PARN

3.85e-0461512cv:C0085786
Diseaseinterstitial lung disease

MUC5B NTM-AS1 CSMD1 MUC5AC

3.93e-04671514EFO_0004244
Diseasetonsillectomy risk measurement

HECTD4 ETV3 PARD3B HEPACAM2 SLCO1B1 DENND2B TRPM3

4.00e-042601517EFO_0007924
DiseaseIschemic stroke, von Willebrand factor measurement

STAB2 VWF HECTD4

4.82e-04301513EFO_0004629, HP_0002140
Diseasehypothyroidism

SASH1 INPP5B MBIP SESN1 STAT4 PLXNC1 TLR3

6.75e-042841517EFO_0004705
Diseasecoronary aneurysm

TIFAB CSMD2 CSMD1

7.62e-04351513EFO_1000881
Diseasebringing up phlegm, sputum or mucus on most days, self-reported

MUC2 MUC5AC

9.15e-0491512EFO_0009824
Diseasecataract (implicated_via_orthology)

DNASE2B TRPM3 VPS13B

9.72e-04381513DOID:83 (implicated_via_orthology)
Diseaseresponse to carboplatin, response to antineoplastic agent

AKNAD1 CSMD1

1.14e-03101512GO_0097327, GO_0097328
Diseasegastric adenocarcinoma (is_implicated_in)

ABCA13 RNF43

1.39e-03111512DOID:3717 (is_implicated_in)
Diseasepulmonary fibrosis

MUC5B MUC5AC

1.39e-03111512EFO_0009448
Diseaseserum IgG glycosylation measurement

CDO1 STAB2 DSCAM LRP1B DNASE2B USF3 GPR158 CSMD1 USH2A

1.54e-035231519EFO_0005193
Diseaseepilepsy (implicated_via_orthology)

UNC13B LRP1B RHOG SLC13A4 BSN

1.55e-031631515DOID:1826 (implicated_via_orthology)
Diseasetriacylglycerol 44:1 measurement

DSCAM CSMD1

1.66e-03121512EFO_0010399
DiseaseAcute Confusional Senile Dementia

MPO ADAMTS1 CR1 DHCR24

1.70e-03991514C0546126
DiseaseAlzheimer's Disease, Focal Onset

MPO ADAMTS1 CR1 DHCR24

1.70e-03991514C0750900
DiseaseAlzheimer Disease, Early Onset

MPO ADAMTS1 CR1 DHCR24

1.70e-03991514C0750901
DiseasePresenile dementia

MPO ADAMTS1 CR1 DHCR24

1.70e-03991514C0011265
DiseaseAlzheimer Disease, Late Onset

MPO ADAMTS1 CR1 DHCR24

1.70e-03991514C0494463
DiseaseFamilial Alzheimer Disease (FAD)

MPO ADAMTS1 CR1 DHCR24

1.77e-031001514C0276496
DiseaseAlzheimer's Disease

MPO ADAMTS1 CR1 DHCR24

1.83e-031011514C0002395
DiseaseDNA methylation

ABCA1 SASH1 ABCA13 PARD3B LRP1B RNF43 NOCT CSMD1 USH2A PMFBP1

2.09e-0365615110GO_0006306
DiseaseHamman-Rich syndrome

MUC5B PARN

2.27e-03141512C0085786
Disease3-hydroxyphenylacetic acid measurement

PIEZO2 PAPPA

2.27e-03141512EFO_0010448
Diseaseresponse to statin, LDL cholesterol change measurement

SLCO1B1 CELSR2

2.61e-03151512EFO_0007804, GO_0036273
Diseasefactor VIII measurement, coronary artery disease

STAB2 VWF SEMA5A CELSR2

2.75e-031131514EFO_0001645, EFO_0004630
Diseasemaximal oxygen uptake measurement, response to exercise

SASH1 ADAMTS1

2.98e-03161512EFO_0004887, EFO_0007768
Diseaselevel of Phosphatidylcholine (18:0_20:3) in blood serum

NOMO1 PARN

2.98e-03161512OBA_2045093
Diseaseperinatal necrotizing enterocolitis (biomarker_via_orthology)

TLR3 MUC2

3.36e-03171512DOID:8677 (biomarker_via_orthology)
DiseaseColorectal Carcinoma

AKAP6 UNC13B MPO CDO1 ABCA1 FN1 ABCA13 RTN4 RNF43 PRPS1

3.40e-0370215110C0009402
Diseasecortical thickness change measurement

PARD3B CSMD1

3.77e-03181512EFO_0021501
Diseasecystic fibrosis (is_marker_for)

MUC5B MUC2 MUC5AC

3.98e-03621513DOID:1485 (is_marker_for)
Diseaseparental longevity

ADAMTS1 HECTD4 ADGRB2 LRP1B CELSR2 AP5Z1 CSMD1 BSN

4.04e-034941518EFO_0007796
Diseaseasthma (is_marker_for)

MPO MUC5B TLR3 MUC5AC

4.07e-031261514DOID:2841 (is_marker_for)
Diseaseautoimmune thyroid disease

SASH1 INPP5B STAT4 TLR3

4.07e-031261514EFO_0006812
DiseaseUsual Interstitial Pneumonia

MUC5B PARN

4.20e-03191512C4721509
DiseaseHamman-Rich Disease

MUC5B PARN

4.20e-03191512C4721508
Diseasecarotid artery disease (is_marker_for)

VWF PAPPA

4.20e-03191512DOID:3407 (is_marker_for)
Diseaseanorectal malformation

MUC5B CSMD2

4.20e-03191512MONDO_0019938
Diseaseglomerulonephritis (is_marker_for)

MPO FN1

4.20e-03191512DOID:2921 (is_marker_for)
Diseaselevel of Sterol ester (27:1/20:3) in blood serum

NOMO1 PARN

4.20e-03191512OBA_2045199
Diseaseinferior parietal cortex volume measurement

DENND2B GREB1

4.20e-03191512EFO_0010307
Diseaseage at onset, smoking initiation

MYCBP2 GRIP1

4.20e-03191512EFO_0004847, EFO_0005670
Diseasecholangiocarcinoma (is_marker_for)

MUC5B MUC2 MUC5AC

4.36e-03641513DOID:4947 (is_marker_for)
Diseasesphingomyelin 16:0 measurement

ABCA1 PARD3B

4.65e-03201512EFO_0010391
DiseaseFamilial Idiopathic Pulmonary Fibrosis

MUC5B PARN

4.65e-03201512C4721952
Diseaseintraocular pressure measurement

CDO1 ABCA1 ADGRB2 RTL10 PARD3B KLHL38 PPP2R3A GPR158

4.82e-035091518EFO_0004695
Diseasevenous thromboembolism, fibrinogen measurement

VWF HECTD4 PMFBP1

4.95e-03671513EFO_0004286, EFO_0004623

Protein segments in the cluster

PeptideGeneStartEntry
DHYLVNFTCLRPSPE

ADGRB2

101

O60241
VHLTPYTVDSPICDF

CCAR2

226

Q8N163
SPHFPSEYENNADCT

CSMD1

221

Q96PZ7
FSYRSSVSFSCHPPL

CSMD2

3086

Q7Z408
RQASFHCKESYLPVP

CXorf49;

241

A8MYA2
VLHLTESPSECYFPS

TBC1D32

976

Q96NH3
VLAFAASPRPNHSYI

FAM117A

321

Q9C073
LFPAPTEYFARVSCS

FAM220BP

101

B1ANY3
ACSVFNYHLSPRTFP

ETV3

306

P41162
HNSGEFAYPCRPQTE

FBXW10

826

Q5XX13
SVRLSYPPYEQHECH

ABCA1

41

O95477
DPNSFAEYHAVVTCP

RTL10

181

Q7L3V2
TSLQYRHPTSEQPSC

CCNJ

286

Q5T5M9
TQAAPYPCHTSDLFL

ABCA13

3551

Q86UQ4
AYCEAHSPPGAATAR

BRPF3

381

Q9ULD4
FVLTPSTEVCSPRYH

AP5Z1

766

O43299
EKPYCQVTTRSFPAH

CELSR2

1361

Q9HCU4
PLSDSETSACRYPSH

DENND2B

46

P78524
FTYFANHTCPERLPS

B4GALT5

106

O43286
FYELEPLASHSCTAP

DISP1

1191

Q96F81
SHFQPRAYSSPVAAL

CECR2

1376

Q9BXF3
HAYPRFTRPSFPSCN

CIRBP-AS1

81

Q8TBR5
SSEFICRNTFDHPYP

DCAF7

56

P61962
IKVSDPSQPCDFHYE

MUC5B

5056

Q9HC84
DCQYSTSHPCFVSRP

NOTCH2NLA

61

Q7Z3S9
VTPRSCHRFEQAFYT

NOMO3

636

P69849
RYEHASFIPSCTPDR

RABEPK

86

Q7Z6M1
SETPLPETDLAHCFY

ADAMTS1

111

Q9UHI8
VPQSCDSLPRYETTH

KAT2A

301

Q92830
TVHQFYCPLPADLSE

PARN

296

O95453
FCSRCSSHSAPLPRY

ZFYVE28

846

Q9HCC9
YCFRDSAQPSAIPEA

BCAN

351

Q96GW7
PAASVFQTCFYRKPH

NTM-AS1

116

Q6ZSK4
PNYARVNHFREPCTS

PARD3B

951

Q8TEW8
VTPRSCHRFEQAFYT

NOMO2

636

Q5JPE7
TQPTVRSHACEVDPY

LRP1B

466

Q9NZR2
NGTTPCAFPTHYEEA

MAGEB2

296

O15479
IHDTVPSAFPSCYEE

MAGEB18

291

Q96M61
TPAAAHSIPYNSCRE

MAVS

121

Q7Z434
ASFPACPQRSYSTEE

MAIP1

86

Q8WWC4
CISHFYPSLLRTPSA

KIAA0825

776

Q8IV33
VPAQYICAPDSKHTF

GREB1

1791

Q4ZG55
FETYHTGCSPDPRTV

LRIG3

941

Q6UXM1
DCQPRAFYLKAHSSP

LRIG3

1061

Q6UXM1
LCYAVRTVPSAFHEP

GPR158

596

Q5T848
EELHRSSCSEYSPSP

BSN

1116

Q9UPA5
AYCPPRFFNHTRLVT

PCSK4

621

Q6UW60
IHPFTACDPSDYERN

PLXNC1

616

O60486
NCSVPFTPVDFHYIR

NXF5

36

Q9H1B4
PTDSQSHCYRTCFSP

PCDHGC5

766

Q9Y5F6
TPFGRCHSAVDPAEY

MUC2

596

Q02817
NSYPRDFVNCSTLPA

MPO

721

P05164
HVEDYSRILCPSSSP

EVPLL

286

A8MZ36
RTCSPTPHFQSDSEY

DDIAS

746

Q8IXT1
VTPRSCHRFEQAFYT

NOMO1

636

Q15155
PHTFAVHSYTRPTIC

PRKD3

271

O94806
PTAVQCFVYSRATFP

GGACT

111

Q9BVM4
TPCFTLHYAAPELLN

RPS6KA5

581

O75582
PTFAACHAHVEPARY

MUC5AC

1101

P98088
RAYPSDHRITTFQSC

HOXA1

26

P49639
RTLPYSYNPCAASHS

PCDHGB3

746

Q9Y5G1
VTQTCFDPDSPHRAY

PAPPA

481

Q13219
IEAACYPRDASPANT

HECTD4

2636

Q9Y4D8
PPGYTRFVCVSDTHS

MPPED1

86

O15442
QFHLYISTSPCGDAR

ADARB1

441

P78563
PYSSLVSCRTHQEVP

ITGB4

1206

P16144
DCQYSTSHPCFVSRP

NOTCH2NLC

61

P0DPK4
RFYFPEGLPDTCSNH

PPP2R3A

711

Q06190
TERPPCTTKDYFQIH

ELAPOR2

341

A8MWY0
CRPHATIAPSAYNNA

PROSER1

206

Q86XN7
DPLYCESVHNFTLPS

ACP3

211

P15309
VPDPSLVNYANFSCS

PAPPA2

1466

Q9BXP8
CYPRNFSAHFVHPAT

GAL3ST3

106

Q96A11
FTDSCSSHPLYNPAE

IDI2

81

Q9BXS1
YTPSSRLSPLEACAH

GSK3A

386

P49840
DFPAHRAVLAAASPY

KLHL21

46

Q9UJP4
FLYHCSDSPLPESAH

BLCAP

66

P62952
PNVYSCSIPATFHQE

DNASE2B

191

Q8WZ79
VNYTCDPHPDRGTSF

CR1

446

P17927
VNYTCDPHPDRGTSF

CR1

896

P17927
VEVPTVSPICRFTYH

ERVK-6

181

Q69384
SHPCTLAFPSYLNDH

DBF4B

571

Q8NFT6
PFQDTSEYIISCHPV

FN1

2216

P02751
QPTDDSCFDPYTVSH

FN1

2291

P02751
AVSLHLYSPPFDTCH

CDO1

151

Q16878
LYSPPFDTCHAFDQR

CDO1

156

Q16878
RCTPSENSDLFYAVP

DHCR24

201

Q15392
QTFISCAPYPHSNEL

GRPR

191

P30550
DNPPVFSSDHYNTCV

FAT3

3126

Q8TDW7
LESASHPNVDRTYFP

DIDO1

916

Q9BTC0
SDPATPSPHFYSCRI

AKNAD1

761

Q5T1N1
ENSCARTDAIFTPYP

MBIP

191

Q9NS73
ESLPEPVICYSTYHN

INPP5B

891

P32019
TSPSQSYRSRFCHPI

KRTAP13-3

136

Q3SY46
HFECPPYNSSTIRSI

DBR1

136

Q9UK59
ILFDCSADSHPPNTY

HEPACAM2

266

A8MVW5
SLAEGYSSRCHPVFQ

ERMARD

421

Q5T6L9
NTYHPDHCRVPALTF

GRIP1

376

Q9Y3R0
SHIYTCPRSAFTVPV

BTN2A2

466

Q8WVV5
LPVLHPSSEASCAYV

SLC13A4

26

Q9UKG4
HNIYPCAFIDSPEFR

BVES

191

Q8NE79
PSFNYPSDHLSLVCD

NOCT

406

Q9UK39
HSYSLCEEPRAQSPF

CREB3L2

81

Q70SY1
HTSLYECPIESSPLF

LAMA4

1396

Q16363
QADFASCTATHRYPP

PMFBP1

281

Q8TBY8
CSHPYPTVISEFEAS

DSCAM

1226

O60469
SDHSETFYECPSTAP

RTL1

601

A6NKG5
YITCAPFNPAATESI

RTN4

461

Q9NQC3
QDCPYRSSHPTYTAL

USH2A

86

O75445
SYELQFHVACPPDSA

USH2A

4861

O75445
INYPLSPTRFTHCEQ

TRIM47

456

Q96LD4
HTFRPPSVSNYCICD

SESN1

231

Q9Y6P5
HYSHPCPRFSQVLLT

BPY2

16

O14599
SFHCRATAEPQPEIY

LRRN3

441

Q9H3W5
CFSIASPPSYENVRH

RHOG

81

P84095
NYPSTASQTNHCPRA

SEC24A

141

O95486
DATVHPACQIFPHYT

RNF43

671

Q68DV7
SFPAQDPCTTIYVAA

SLAMF1

296

Q13291
FFAYFQCTPSLDTHP

THNSL2

236

Q86YJ6
SSVSPNPEACITYHE

SH3TC2

971

Q8TF17
FTACFHSFYPTPALQ

MYCBP2

1546

O75592
AAFSHPQAAQLCYEP

SPIB

66

Q01892
SASRVTAVIPCFPYA

PRPS1L1

81

P21108
ARPSDQVFCYNPATD

KBTBD11

376

O94819
NPVTSHRDVPLSYCN

SLCO1B1

446

Q9Y6L6
RPISHTPSYCDESLF

RITA1

101

Q96K30
VLPQNRSSPCIHYFT

SCRN1

281

Q12765
CPYSPQHNSTALLTA

SEMA5A

161

Q13591
FSVRKTAYCDIHTPP

BRPF1

436

P55201
AAPHLSTFDPCFYRE

B3GNT9

346

Q6UX72
PNSPSAASQSYECLH

AKAP6

446

Q13023
ACEEAPPSAAHFRFY

CILP

901

O75339
PPEFIHLYISNCIST

CNOT11

421

Q9UKZ1
TNIPELSSHYLCNTP

TLR3

666

O15455
SKNTCEHIYDFPPLS

UNC119

186

Q13432
TFEACHRAVSPLPYL

VWF

591

P04275
ISSFCYRPRPDSYHL

SLC5A2

251

P31639
YPVCTVRYFPSTAEH

UBA7

596

P41226
FGKHYSSQPCEVSRP

STAT4

671

Q14765
SFSSDYTHLPECQNP

TRPM3

1496

Q9HCF6
FRSIPNCTVFYPSDA

TKTL2

441

Q9H0I9
PHCARTFTHPSRLTY

ZNF398

401

Q8TD17
AFPSISRPQFDYSDH

SOX10

391

P56693
SQHNPVPDFIHCRSY

PIEZO2

1271

Q9H5I5
NFTLSPTGDVYCTRH

WDFY4

2421

Q6ZS81
PHTPYHIRVACTSSQ

AXL

301

P30530
SLEAFVCYFHVSPSP

TIFAB

121

Q6ZNK6
CGRARVHTDFTPSPY

SASH1

556

O94885
NSEPTALFTHRCVYS

STAB2

691

Q8WWQ8
CYPVPANTSASFLNH

TTC14

536

Q96N46
SSAIEYNCPPTHENV

USF3

1851

Q68DE3
QALIYPISCTTPHNF

UNC13B

466

O14795
FSHVYTCAQVPARSP

ZNF862

1096

O60290
SHFEPERPYQCAFSG

ZXDA

381

P98168
SVCNPHSGKEYFRVP

VPS13B

3126

Q7Z7G8
SASRVTAVIPCFPYA

PRPS1

81

P60891
YLSRSDSAEQPHAPC

ZNF831

346

Q5JPB2
VSTLCYFTRSPPSLH

VN1R3

241

Q9BXE9
HFSSDAVPHPRFYCV

UBR4

921

Q5T4S7
FYPATRDIFPSAHAS

WDR87

2666

Q6ZQQ6
QCTRPDCTFYHPTIN

ZC3H14

706

Q6PJT7
SYPLATCPERNVLFH

TEX38

171

Q6PEX7
SPHDSHTCVTYPERN

USP54

1286

Q70EL1
FIPVYPCHQTASQAD

WNK3

1001

Q9BYP7
PCHRNVLASSSPYFR

KLHL38

46

Q2WGJ6
AHTNTTVAPIYCASP

LGI3

186

Q8N145