Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	4-hydroxybutyrate receptor activity	SLC52A1 SLC52A2	1.51e-05	2	78	2	GO:0062124
GeneOntologyMolecularFunction	riboflavin transmembrane transporter activity	SLC52A1 SLC52A2	2.24e-04	6	78	2	GO:0032217
GeneOntologyBiologicalProcess	detection of mechanical stimulus involved in sensory perception	BACE1 ADGRV1 STRC STRCP1	6.42e-05	57	78	4	GO:0050974
GeneOntologyBiologicalProcess	detection of mechanical stimulus involved in sensory perception of sound	ADGRV1 STRC STRCP1	8.72e-05	23	78	3	GO:0050910
GeneOntologyBiologicalProcess	flavin-containing compound biosynthetic process	SLC52A1 SLC52A2	1.40e-04	5	78	2	GO:0042727
GeneOntologyBiologicalProcess	riboflavin metabolic process	SLC52A1 SLC52A2	1.40e-04	5	78	2	GO:0006771
GeneOntologyBiologicalProcess	flavin adenine dinucleotide biosynthetic process	SLC52A1 SLC52A2	1.40e-04	5	78	2	GO:0072388
GeneOntologyBiologicalProcess	detection of mechanical stimulus	BACE1 ADGRV1 STRC STRCP1	1.88e-04	75	78	4	GO:0050982
GeneOntologyBiologicalProcess	flavin-containing compound metabolic process	SLC52A1 SLC52A2	2.10e-04	6	78	2	GO:0042726
GeneOntologyBiologicalProcess	flavin adenine dinucleotide metabolic process	SLC52A1 SLC52A2	2.10e-04	6	78	2	GO:0072387
GeneOntologyBiologicalProcess	riboflavin transport	SLC52A1 SLC52A2	2.10e-04	6	78	2	GO:0032218
MousePheno	abnormal synaptic transmission	HSPG2 TTC28 CTC1 ICAM5 CASKIN1 DYRK1B BACE1 DUOX2 DLG4 FAM53B ADGRV1 PREX1 NEURL4 SHISA7 RYR2 TASOR2	2.24e-05	1070	65	16	MP:0003635
MousePheno	abnormal synaptic physiology	HSPG2 TTC28 CTC1 ICAM5 CASKIN1 DYRK1B BACE1 DUOX2 DLG4 FAM53B ADGRV1 PREX1 NEURL4 SHISA7 RYR2 TASOR2	2.40e-05	1076	65	16	MP:0021009
MousePheno	abnormal CNS synaptic transmission	TTC28 CTC1 ICAM5 CASKIN1 DYRK1B BACE1 DUOX2 DLG4 FAM53B ADGRV1 PREX1 NEURL4 SHISA7 RYR2 TASOR2	3.46e-05	985	65	15	MP:0002206
Domain	Riboflavin_transptr	SLC52A1 SLC52A2	4.89e-05	3	76	2	IPR009357
Domain	DUF1011	SLC52A1 SLC52A2	4.89e-05	3	76	2	PF06237
Domain	EGF_LAM_2	HSPG2 CELSR2 LAMA3	2.43e-04	30	76	3	PS50027
Domain	EGF_LAM_1	HSPG2 CELSR2 LAMA3	2.43e-04	30	76	3	PS01248
Domain	ConA-like_dom	HSPG2 CELSR2 LAMA3 ADGRV1 NEURL4 RYR2	2.68e-04	219	76	6	IPR013320
Domain	Laminin_EGF	HSPG2 CELSR2 LAMA3	3.86e-04	35	76	3	PF00053
Domain	EGF_Lam	HSPG2 CELSR2 LAMA3	3.86e-04	35	76	3	SM00180
Domain	LAMININ_IVA	HSPG2 LAMA3	4.50e-04	8	76	2	PS51115
Domain	Laminin_B	HSPG2 LAMA3	4.50e-04	8	76	2	PF00052
Domain	LamB	HSPG2 LAMA3	4.50e-04	8	76	2	SM00281
Domain	Laminin_IV	HSPG2 LAMA3	4.50e-04	8	76	2	IPR000034
Domain	LAM_G_DOMAIN	HSPG2 CELSR2 LAMA3	4.93e-04	38	76	3	PS50025
Domain	Laminin_EGF	HSPG2 CELSR2 LAMA3	4.93e-04	38	76	3	IPR002049
Domain	Laminin_G_2	HSPG2 CELSR2 LAMA3	5.74e-04	40	76	3	PF02210
Domain	Acyl-CoA_DH_CS	ACAD8 GCDH	5.77e-04	9	76	2	IPR006089
Domain	-	HSPG2 CELSR2 LAMA3 ADGRV1	6.09e-04	95	76	4	2.60.120.200
Domain	ACYL_COA_DH_1	ACAD8 GCDH	7.20e-04	10	76	2	PS00072
Domain	ACYL_COA_DH_2	ACAD8 GCDH	7.20e-04	10	76	2	PS00073
Domain	LamG	HSPG2 CELSR2 LAMA3	7.61e-04	44	76	3	SM00282
Domain	Acyl-CoA_dh_N	ACAD8 GCDH	8.78e-04	11	76	2	PF02771
Domain	AcylCoA_DH/ox_N	ACAD8 GCDH	1.24e-03	13	76	2	IPR013786
Domain	-	ACAD8 GCDH	1.24e-03	13	76	2	1.10.540.10
Domain	Acyl-CoA_dh_1	ACAD8 GCDH	1.24e-03	13	76	2	PF00441
Domain	Acyl-CoA_Oxase/DH_cen-dom	ACAD8 GCDH	1.66e-03	15	76	2	IPR006091
Domain	Acyl-CoA_dh_M	ACAD8 GCDH	1.66e-03	15	76	2	PF02770
Domain	AcylCoA_DH/oxidase_NM_dom	ACAD8 GCDH	1.66e-03	15	76	2	IPR009100
Domain	Laminin_G	HSPG2 CELSR2 LAMA3	1.70e-03	58	76	3	IPR001791
Domain	Ank_2	GLS2 ASPG CASKIN1 ANKRD34C ANKS3	1.84e-03	215	76	5	PF12796
Domain	AcylCo_DH/oxidase_C	ACAD8 GCDH	1.89e-03	16	76	2	IPR009075
Domain	Fd_Rdtase_FAD-bd	DUOX2 OXNAD1	2.67e-03	19	76	2	IPR017927
Domain	FAD_FR	DUOX2 OXNAD1	2.67e-03	19	76	2	PS51384
Domain	Riboflavin_synthase-like_b-brl	DUOX2 OXNAD1	2.67e-03	19	76	2	IPR017938
Domain	-	GLS2 ASPG CASKIN1 ANKRD34C ANKS3	3.40e-03	248	76	5	1.25.40.20
Domain	ANK	GLS2 ASPG CASKIN1 ANKRD34C ANKS3	3.58e-03	251	76	5	SM00248
Domain	ANK_REPEAT	GLS2 ASPG CASKIN1 ANKRD34C ANKS3	3.71e-03	253	76	5	PS50088
Domain	Ankyrin_rpt-contain_dom	GLS2 ASPG CASKIN1 ANKRD34C ANKS3	3.77e-03	254	76	5	IPR020683
Domain	ANK_REP_REGION	GLS2 ASPG CASKIN1 ANKRD34C ANKS3	3.77e-03	254	76	5	PS50297
Domain	G_patch	AGGF1 GPKOW	3.91e-03	23	76	2	SM00443
Domain	G_patch_dom	AGGF1 GPKOW	3.91e-03	23	76	2	IPR000467
Domain	G_PATCH	AGGF1 GPKOW	3.91e-03	23	76	2	PS50174
Domain	G-patch	AGGF1 GPKOW	3.91e-03	23	76	2	PF01585
Domain	Ankyrin_rpt	GLS2 ASPG CASKIN1 ANKRD34C ANKS3	4.30e-03	262	76	5	IPR002110
Domain	FERM_C	FRMPD2 FARP2	4.99e-03	26	76	2	PF09380
Domain	FERM_C	FRMPD2 FARP2	5.37e-03	27	76	2	SM01196
Domain	FERM_PH-like_C	FRMPD2 FARP2	5.37e-03	27	76	2	IPR018980
Pubmed	Mutations in a new gene encoding a protein of the hair bundle cause non-syndromic deafness at the DFNB16 locus.	STRC STRCP1	5.23e-06	2	80	2	11687802
Pubmed	Distribution of Caskin1 protein and phenotypic characterization of its knockout mice using a comprehensive behavioral test battery.	ICAM5 CASKIN1	5.23e-06	2	80	2	30359304
Pubmed	Riboflavin uptake transporter Slc52a2 (RFVT2) is upregulated in the mouse mammary gland during lactation.	SLC52A1 SLC52A2	5.23e-06	2	80	2	26791833
Pubmed	Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss.	STRC STRCP1	5.23e-06	2	80	2	34910522
Pubmed	The AMPA receptor-associated protein Shisa7 regulates hippocampal synaptic function and contextual memory.	DLG4 SHISA7	5.23e-06	2	80	2	29199957
Pubmed	Complete Deletion of Slc52a2 Causes Embryonic Lethality in Mice.	SLC52A1 SLC52A2	5.23e-06	2	80	2	33518683
Pubmed	Identification of receptors for pig endogenous retrovirus.	SLC52A1 SLC52A2	5.23e-06	2	80	2	12740431
Pubmed	Involvement of riboflavin transporter RFVT2/Slc52a2 in hepatic homeostasis of riboflavin in mice.	SLC52A1 SLC52A2	5.23e-06	2	80	2	23911957
Pubmed	Madras motor neuron disease (MMND) is distinct from the riboflavin transporter genetic defects that cause Brown-Vialetto-Van Laere syndrome.	SLC52A1 SLC52A2	1.57e-05	3	80	2	24139842
Pubmed	Cochlear outer hair cell horizontal top connectors mediate mature stereocilia bundle mechanics.	STRC STRCP1	1.57e-05	3	80	2	30801007
Pubmed	SLC52A3, A Brown-Vialetto-van Laere syndrome candidate gene is essential for mouse development, but dispensable for motor neuron differentiation.	SLC52A1 SLC52A2	1.57e-05	3	80	2	26976849
Pubmed	The Expression of Riboflavin Transporters in Human Colorectal Cancer.	SLC52A1 SLC52A2	1.57e-05	3	80	2	29715086
Pubmed	Riboflavin Transporter Deficiency	SLC52A1 SLC52A2	1.57e-05	3	80	2	26072523
Pubmed	Novel riboflavin transporter family RFVT/SLC52: identification, nomenclature, functional characterization and genetic diseases of RFVT/SLC52.	SLC52A1 SLC52A2	1.57e-05	3	80	2	23506902
Pubmed	Identification and comparative functional characterization of a new human riboflavin transporter hRFT3 expressed in the brain.	SLC52A1 SLC52A2	1.57e-05	3	80	2	20463145
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	PABIR1 PDE3B TTC28 PI4KB DYRK1B FAM53B PFKP CDC25B PC DENND2B	2.83e-05	861	80	10	36931259
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PLCH2 CASKIN1 FAM53B ADGRV1 KBTBD2 SHOC2 ANKS3 SMG6	3.02e-05	529	80	8	14621295
Pubmed	Stereocilin-deficient mice reveal the origin of cochlear waveform distortions.	STRC STRCP1	3.13e-05	4	80	2	18849963
Pubmed	Cell mixing at a neural crest-mesoderm boundary and deficient ephrin-Eph signaling in the pathogenesis of craniosynostosis.	MSX2 EFNA4	5.20e-05	5	80	2	16540516
Pubmed	An unusually powerful mode of low-frequency sound interference due to defective hair bundles of the auditory outer hair cells.	STRC STRCP1	5.20e-05	5	80	2	24920589
Pubmed	Synaptic NMDA receptor activation stimulates alpha-secretase amyloid precursor protein processing and inhibits amyloid-beta production.	BACE1 DLG4	5.20e-05	5	80	2	19357271
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CELSR2 HECW1 ICAM5 CASKIN1 WDR18 DLG4 NEURL4 SHISA7 PRRC2B SMG6	7.22e-05	963	80	10	28671696
Pubmed	Detection of mutations in LRPAP1, CTSH, LEPREL1, ZNF644, SLC39A5, and SCO2 in 298 families with early-onset high myopia by exome sequencing.	SCO2 SLC39A5	7.79e-05	6	80	2	25525168
Pubmed	Stereocilin connects outer hair cell stereocilia to one another and to the tectorial membrane.	STRC STRCP1	1.45e-04	8	80	2	21165971
Pubmed	Activity-dependent and graded BACE1 expression in the olfactory epithelium is mediated by the retinoic acid metabolizing enzyme CYP26B1.	BACE1 KIRREL2	1.45e-04	8	80	2	24797530
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	HECW1 TTC28 ADGRV1 PREX1 SMG6	1.76e-04	225	80	5	12168954
Pubmed	Ctip2/Bcl11b controls ameloblast formation during mammalian odontogenesis.	MSX2 LAMA3	1.86e-04	9	80	2	19251658
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MSX2 HSPG2 CELSR2 CTC1 CASKIN1 SLC52A2 PC PREX1 PRRC2B SMG6	2.21e-04	1105	80	10	35748872
Pubmed	Clarin-2 is essential for hearing by maintaining stereocilia integrity and function.	STRC STRCP1	2.84e-04	11	80	2	31448880
Pubmed	Otogelin, otogelin-like, and stereocilin form links connecting outer hair cell stereocilia to each other and the tectorial membrane.	STRC STRCP1	2.84e-04	11	80	2	31776257
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	ACAD8 CTC1 AGGF1 WDR18 CDC25B SHOC2 GPKOW NEURL4 PRRC2B TASOR2	3.14e-04	1155	80	10	20360068
Pubmed	Molecular dissection of laminin alpha 5 in vivo reveals separable domain-specific roles in embryonic development and kidney function.	HSPG2 LAMA3	3.40e-04	12	80	2	16750824
Pubmed	Effect of riboflavin deficiency on development of the cerebral cortex in Slc52a3 knockout mice.	SLC52A1 SLC52A2	3.40e-04	12	80	2	33116204
Pubmed	Evidence for complex multigenic inheritance of radiation AML susceptibility in mice revealed using a surrogate phenotypic assay.	MSX2 LAMA3	4.01e-04	13	80	2	16093251
Pubmed	Kirrel3 is required for the coalescence of vomeronasal sensory neuron axons into glomeruli and for male-male aggression.	DLG4 KIRREL2	4.01e-04	13	80	2	23637329
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	TTC28 PI4KB KBTBD2 AGPS PC RYR2 PRRC2B TASOR2	4.21e-04	777	80	8	35844135
Pubmed	Genetic and physical delineation of the region overlapping the progressive motor neuropathy (pmn) locus on mouse chromosome 13.	HECW1 RYR2	4.67e-04	14	80	2	11472062
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	TTC28 DYRK1B WDR18 GCDH PFKP GTPBP3 PC	4.99e-04	606	80	7	36538041
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	TTC28 TAF1C AGGF1 WDR18 DPP3 PFKP CDC25B NEURL4 PRRC2B	5.01e-04	1005	80	9	19615732
Pubmed	Basement membrane composition in the early mouse embryo day 7.	HSPG2 LAMA3	5.38e-04	15	80	2	15895400
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	CPAMD8 PDE3B TDH LOXL2 FRMPD2 LAMA3 ADGRV1 DENND2B TASOR2 SMG6 FARP2	5.93e-04	1489	80	11	28611215
Pubmed	No replication of genetic association between candidate polymorphisms and Alzheimer's disease.	HSPG2 BACE1	6.14e-04	16	80	2	19889475
Pubmed	ADAMTS18 Deficiency Affects Neuronal Morphogenesis and Reduces the Levels of Depression-like Behaviors in Mice.	LAMA3 DLG4	6.14e-04	16	80	2	30579834
Pubmed	Breakdown of the reciprocal stabilization of QBRICK/Frem1, Fras1, and Frem2 at the basement membrane provokes Fraser syndrome-like defects.	HSPG2 LAMA3	6.14e-04	16	80	2	16880404
Pubmed	Mammalian Otolin: a multimeric glycoprotein specific to the inner ear that interacts with otoconial matrix protein Otoconin-90 and Cerebellin-1.	STRC STRCP1	6.95e-04	17	80	2	20856818
Pubmed	TRIM67 Implicates in Regulating the Homeostasis and Synaptic Development of Mitral Cells in the Olfactory Bulb.	PLXNC1 DLG4	8.71e-04	19	80	2	37686246
Pubmed	Laminin and integrin expression in the ventral ectodermal ridge of the mouse embryo: implications for regulation of BMP signalling.	MSX2 LAMA3	9.66e-04	20	80	2	22911573
Pubmed	An atlas of genetic influences on human blood metabolites.	GLS2 ASPG GCDH F12	9.87e-04	190	80	4	24816252
Pubmed	Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells.	PABIR1 PNMT DPP3 PFKP GPKOW	1.00e-03	330	80	5	21044950
Pubmed	Comprehensive proteomic characterization of stem cell-derived extracellular matrices.	HSPG2 GDF15 LOXL2	1.05e-03	86	80	3	28327460
Pubmed	Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.	PDE3B DLG4	1.07e-03	21	80	2	22479202
Pubmed	PDGFRβ regulates craniofacial development through homodimers and functional heterodimers with PDGFRα.	HSPG2 LAMA3	1.07e-03	21	80	2	27856617
Pubmed	Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.	SCO2 CRYZ ACAD8 GLS2 MTHFD2L OXNAD1 GCDH GTPBP3 PC	1.19e-03	1136	80	9	34800366
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	AMER2 CELSR2 HECW1 CASKIN1 DLG4 PC SHOC2 SHISA7 RYR2	1.21e-03	1139	80	9	36417873
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	AMER2 CASKIN1 DYRK1B GPR37L1 DLG4	1.25e-03	347	80	5	17114649
Pubmed	Oct4 links multiple epigenetic pathways to the pluripotency network.	HSPG2 TDH SHOC2 PRRC2B	1.26e-03	203	80	4	22083510
Pubmed	Uncovering quantitative protein interaction networks for mouse PDZ domains using protein microarrays.	GLS2 DLG4	1.28e-03	23	80	2	16637659
Pubmed	Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.	ACAD8 GLS2 MTHFD2L OXNAD1 GCDH AGPS GTPBP3 PC	1.31e-03	926	80	8	20877624
Pubmed	The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.	DLG4 SHOC2 PRRC2B SMG6	1.64e-03	218	80	4	33378226
Pubmed	Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.	PI4KB FAM53B DENND2B	1.71e-03	102	80	3	15778465
Pubmed	Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.	FAM83E DPP3 PC	1.71e-03	102	80	3	21926972
Pubmed	Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.	HSPG2 LAMA3	2.04e-03	29	80	2	22613833
Pubmed	Neurotransmitter release regulated by a MALS-liprin-alpha presynaptic complex.	CASKIN1 DLG4	2.18e-03	30	80	2	16186258
Cytoband	15q15.3	DUOX2 STRC STRCP1	1.14e-05	25	80	3	15q15.3
Cytoband	19p13.11	CPAMD8 GDF15 GTPBP3	2.90e-04	73	80	3	19p13.11
Cytoband	Ensembl 112 genes in cytogenetic band chr17p13	SLC52A1 CTC1 DLG4 NEURL4 SMG6	3.58e-04	346	80	5	chr17p13
Cytoband	Ensembl 112 genes in cytogenetic band chr19p13	CPAMD8 GDF15 ICAM5 WDR18 GCDH GTPBP3	2.72e-03	797	80	6	chr19p13
GeneFamily	Acyl-CoA dehydrogenase family	ACAD8 GCDH	3.74e-04	11	48	2	974
GeneFamily	Ankyrin repeat domain containing	GLS2 ASPG CASKIN1 ANKRD34C ANKS3	4.41e-04	242	48	5	403
GeneFamily	G-patch domain containing\|Minor histocompatibility antigens	AGGF1 GPKOW	1.54e-03	22	48	2	579
GeneFamily	PDZ domain containing	FRMPD2 DLG4 PREX1	7.64e-03	152	48	3	1220
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	FRMPD2 FARP2	7.80e-03	50	48	2	1293
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	HSPG2 KIRREL2 LRIT1	8.94e-03	161	48	3	593
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PREX1 FARP2	1.33e-02	66	48	2	722
GeneFamily	Immunoglobulin like domain containing	HSPG2 ICAM5 KIRREL2	1.46e-02	193	48	3	594
GeneFamily	EF-hand domain containing	PLCH2 DUOX2 RYR2	2.03e-02	219	48	3	863
GeneFamily	Sterile alpha motif domain containing	CASKIN1 ANKS3	2.29e-02	88	48	2	760
Coexpression	VECCHI_GASTRIC_CANCER_EARLY_UP	MSX2 EFNA4 GDF15 LAMA3 DPP3 SLC52A2 TMEM68 PFKP CDC25B F12	7.58e-07	436	79	10	M18855
ToppCell	wk_15-18-Epithelial-Distal_epithelial-type_I_pneumocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	HSPG2 CPAMD8 CELSR2 ASPG GDF15 LAMA3 ADGRV1	2.87e-08	174	80	7	2cd6638b361ca05ab83d09ce657194aed97873b7
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	HSPG2 CPAMD8 ASPG GDF15 ICAM5 LAMA3 ADGRV1	4.71e-08	187	80	7	4ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCell	Hippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Nxph3-Excitatory_Neuron.Slc17a7.Nxph3-Cplx3-Hs6st2_(Entorhinal_cortex)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	DUOX2 STRC SLC39A5 F12	6.92e-06	68	80	4	75e81b353ef313d5e98d5c98d584335f1d1fa658
ToppCell	Hippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Nxph3-Excitatory_Neuron.Slc17a7.Nxph3-Cplx3-Hs6st2_(Entorhinal_cortex)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	DUOX2 STRC SLC39A5 F12	6.92e-06	68	80	4	01ba0ccc5732189a5c0c32cb7819289102711b93
ToppCell	Hippocampus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Myoc_(Myoc)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	MSX2 ASPG FAM83E RAX	1.39e-05	81	80	4	2c58dbad21e0fbe46b005bcaf45139d098a2057a
ToppCell	Hippocampus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Myoc_(Myoc)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	MSX2 ASPG FAM83E RAX	1.39e-05	81	80	4	a0b45dc22077805eba94689568b874415f515d61
ToppCell	Hippocampus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Myoc_(Myoc)--\|Hippocampus / BrainAtlas - Mouse McCarroll V32	MSX2 ASPG FAM83E RAX	1.39e-05	81	80	4	571884bcf4282053c6170609ae0c794a6df05cd9
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CELSR2 GDF15 ICAM5 LAMA3 ADGRV1	1.78e-05	179	80	5	cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCell	Fetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PDE3B AMER2 LINC00472 PREX1 DENND2B	2.20e-05	187	80	5	97b2463fb37e7196dd2f92553acf8e7bc3ec40dd
ToppCell	Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|World / Lineage, Cell type, age group and donor	CPAMD8 CELSR2 GDF15 LAMA3 ADGRV1	2.43e-05	191	80	5	d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	CPAMD8 PDE3B FAM53B KIRREL2 F12	3.03e-05	200	80	5	be83f442179ba4217d12f0458059586ff3130991
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-Treg_6\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HECW1 FRMPD2 LINC00472 RAX	3.19e-05	100	80	4	60c2bdee5d37dedf9be1e03b6b52b539a2277df3
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-Treg_6\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	HECW1 FRMPD2 LINC00472 RAX	3.32e-05	101	80	4	de49feca7548640f85d206ebc56a58ab0bf7ac16
Drug	flavin adenine dinucleotide sodium	CRYZ ACAD8 ICAM5 LOXL2 BACE1 DUOX2 GCDH SIRT7 AGPS NEURL4	3.77e-07	356	78	10	CID000000703
Disease	autosomal recessive nonsyndromic deafness 16 (implicated_via_orthology)	STRC STRCP1	6.72e-06	2	77	2	DOID:0110471 (implicated_via_orthology)
Disease	Brown-Vialetto-Van Laere syndrome (implicated_via_orthology)	SLC52A1 SLC52A2	2.01e-05	3	77	2	DOID:0050694 (implicated_via_orthology)
Disease	ovarian carcinoma	SLC52A1 TTC28 RCCD1 FRMPD2 LAMA3 ADGRV1	1.96e-04	321	77	6	EFO_0001075
Disease	ovarian serous carcinoma	TTC28 RCCD1 LAMA3	2.39e-04	46	77	3	EFO_1001516
Disease	glutamine measurement, amino acid measurement	GLS2 ASPG	3.64e-04	11	77	2	EFO_0005134, EFO_0009768
Disease	myopia (is_implicated_in)	SCO2 SLC39A5	7.88e-04	16	77	2	DOID:11830 (is_implicated_in)
Disease	apolipoprotein B measurement	PDE3B CELSR2 BACE1 DLG4 EPS8L3 F12 FARP2	1.73e-03	663	77	7	EFO_0004615
Disease	L-arginine measurement	GCDH F12	2.26e-03	27	77	2	EFO_0006524
Disease	hypertrophic cardiomyopathy (implicated_via_orthology)	SCO2 GTPBP3	2.61e-03	29	77	2	DOID:11984 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
LRGRGRGILILPAHT	SMG6	401	Q86US8
GTQHGIRLPLRSGLG	BACE1	21	P56817
GPTGLVRSRTHDGLA	AMER2	96	Q8N7J2
GSGTLLLDRISHTRP	ANKRD34C	446	P0C6C1
VHLLQSVGGGTRRPV	CTC1	406	Q2NKJ3
LPGGLRVLVQTGHRS	ACAD8	16	Q9UKU7
IRTSGPASGHALRIL	GTPBP3	51	Q969Y2
ATGGAVLGRHLVSRI	ADGRV1	4491	Q8WXG9
LQLRRTHAGLGTGKP	AGGF1	651	Q8N302
GPRLHGLHLSNITVG	CELSR2	1731	Q9HCU4
RPRQHGLLLSGALGT	DNHD1	2881	Q96M86
GPRGVLLTRTGTRAH	DENND2B	146	P78524
TLGPHLGLRGVPQST	DYRK1B	611	Q9Y463
LGSGRGRQVHSPSPL	RCCD1	21	A6NED2
GGSLPSRHQIVGSRL	HSPG2	2571	P98160
LLSHGGRVIVVGSRG	CRYZ	236	Q08257
LSGPVTGLLATARRG	CASKIN1	1066	Q8WXD9
IRPRSLTGILIHIGS	LAMA3	3186	Q16787
LLLAVRGRHPGVIGL	ASPG	471	Q86U10
RGASLLARPGHSLVA	HECW1	1086	Q76N89
GLGVSRAPLHLLLGV	LINC02872	6	A2RU37
VTGSRLGQGIGPIHL	LOXL2	376	Q9Y4K0
GIAGLPSLHNRTVLG	DUOX2	91	Q9NRD8
LALSGTRARGHLPPG	CYP2S1	21	Q96SQ9
HPVGGGRLDLQRSLS	FAM53B	216	Q14153
GHPDGRRLLLSSSLV	PLXNC1	286	O60486
GAGPRASLTLTLLRG	ICAM5	146	Q9UMF0
HVGLRRAGVLSSLSP	PDE3B	501	Q13370
RVTILGHVQRGGTPS	PFKP	301	Q01813
LGSPLRGGSSLRHVV	EFNA4	16	P52798
LGSLTGSQLLRIRPG	EPS8L3	551	Q8TE67
HGPTRRLRGLGVLAG	FUT7	6	Q11130
GLHIATNSGIRLPSG	KBTBD2	476	Q8IY47
GLLLGSHGLLGSPVR	CDC25B	31	P30305
PRLRHLGLGKEGITT	DPP3	156	Q9NY33
LGPQTGRVGHLLSRD	GPKOW	426	Q92917
PSRSPLLGGGVRHHL	GLS2	26	Q9UI32
VRILTPEVRLGSGGH	GDF15	86	Q99988
PEVRLGSGGHLHLRI	GDF15	91	Q99988
GLRRSNSAPLIHGLS	PABIR1	31	Q96E09
LHPGVASIRSLLGGT	LRIT1	256	Q9P2V4
AGGVGINPLLSILRH	OXNAD1	176	Q96HP4
SVRGLPHLGLRISGT	LINC00472	106	Q9H8W2
VSVRLLSRGPGLHVL	GCDH	6	Q92947
PAGLHIRRLVGLVLG	FRMPD2	171	Q68DX3
AVGLSRVSGGAPLHL	GPR37L1	16	O60883
SGRVVGAHRPGLLSP	CPAMD8	1846	Q8IZJ3
PRRIVIHRGSTGLGF	DLG4	311	P78352
HEGPRALARITGIGL	ANKS3	266	Q6ZW76
ESRGGLGPGLISVLH	KIRREL2	456	Q6UWL6
GTSHFRIRGLLPLQG	FARP2	791	O94887
VLPGTLGGQALHLRS	SCO2	21	O43819
HGLPGIGLSTSLRPR	RYR2	1746	Q92736
GGELHPRTGRLVSLS	NEURL4	41	Q96JN8
SAGATLRPLLLSGHG	MSX2	71	P35548
TRVVGGLVALRGAHP	F12	371	P00748
VIGGLQRGRSPHRVS	FAM83E	301	Q2M2I3
ILGGPILGTSVASHL	TAF1C	176	Q15572
VAASSLLHGGGRPAL	SLC52A2	391	Q9HAB3
LPSRLEGGASLRLHT	PREX1	1451	Q8TCU6
LPRGIGHLTNLTHLG	SHOC2	486	Q9UQ13
LLAHLRRLTGALTGG	SHISA7	36	A6NL88
EPRHGGLTLRLGLHQ	WDR18	351	Q9BV38
GLHLRSGLPRTAISE	SIRT7	171	Q9NRC8
LLHGGVAVSSRGTPL	PI4KB	61	Q9UBF8
GLGPGHARHVLRSLV	STRC	901	Q7RTU9
GGLARLLHSLGLGRV	SLC39A5	56	Q6ZMH5
LLRSPGGSTSRLHSI	RAX	21	Q9Y2V3
LSGHLLGRPREALST	AGPS	41	O00116
ITTLLRPGGHLLLIG	PNMT	201	P11086
ILRSGHLLAISPGGV	TMEM68	186	Q96MH6
ASSLLHGGGRPALLA	SLC52A1	396	Q9NWF4
LSHSLGLPGGTRRVS	PLCH2	1276	O75038
PVGHEGGLRGSSRLL	PRRC2B	151	Q5JSZ5
SLGNRRPHLSIILVG	MTHFD2L	76	Q9H903
SSGPVGRHRQLILVL	TTC28	1411	Q96AY4
GLGPGHARHVLRSLV	STRCP1	901	A6NGW2
LILTDHPGRTGRPTL	TASOR2	1481	Q5VWN6
TVHGGLRLLGIRRTS	PC	6	P11498
VHGLPGSGKTILALR	SLFN5	576	Q08AF3
HPRVLITGALGQLGV	TDH	51	Q8IZJ6