Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainHELP

EML4 EML1

3.25e-046882PF03451
DomainDUSP

USP32 USP33

3.25e-046882PF06337
DomainDUSP

USP32 USP33

3.25e-046882SM00695
DomainHELP

EML4 EML1

3.25e-046882IPR005108
DomainDUSP

USP32 USP33

4.54e-047882PS51283
Domain-

USP32 USP33

4.54e-0478823.30.2230.10
DomainPept_C19_DUSP

USP32 USP33

4.54e-047882IPR006615
DomainLAM_G_DOMAIN

CNTNAP3B FAT3 CNTNAP3

7.57e-0438883PS50025
DomainLaminin_G_2

CNTNAP3B FAT3 CNTNAP3

8.80e-0440883PF02210
DomainEFh

CAPN8 CABP5 PPP3R1 USP32 RYR2

9.05e-04158885SM00054
DomainCENP-B_N

TIGD7 TIGD2

9.64e-0410882PF04218
DomainLamG

CNTNAP3B FAT3 CNTNAP3

1.16e-0344883SM00282
DomainHTH_Psq

TIGD7 TIGD2

1.40e-0312882IPR007889
DomainHTH_PSQ

TIGD7 TIGD2

1.40e-0312882PS50960
DomainCENPB

TIGD7 TIGD2

1.40e-0312882SM00674
DomainDDE_1

TIGD7 TIGD2

1.40e-0312882PF03184
DomainDDE_SF_endonuclease_dom

TIGD7 TIGD2

1.40e-0312882IPR004875
DomainHTH_CENPB

TIGD7 TIGD2

1.66e-0313882PS51253
DomainHTH_Tnp_Tc5

TIGD7 TIGD2

1.66e-0313882PF03221
DomainHTH_CenpB_DNA-bd_dom

TIGD7 TIGD2

1.66e-0313882IPR006600
DomainuDENN

DENND4A DENND1B

1.93e-0314882SM00800
DomainuDENN

DENND4A DENND1B

2.21e-0315882PF03456
DomainDENN

DENND4A DENND1B

2.52e-0316882SM00799
DomainDENN

DENND4A DENND1B

2.52e-0316882PF02141
DomaindDENN

DENND4A DENND1B

2.52e-0316882PF03455
DomainUDENN

DENND4A DENND1B

2.52e-0316882PS50946
DomainDDENN

DENND4A DENND1B

2.52e-0316882PS50947
DomaindDENN

DENND4A DENND1B

2.52e-0316882SM00801
DomaindDENN_dom

DENND4A DENND1B

2.52e-0316882IPR005112
DomainuDENN_dom

DENND4A DENND1B

2.52e-0316882IPR005113
DomainDENN

DENND4A DENND1B

2.52e-0316882PS50211
DomainDENN_dom

DENND4A DENND1B

2.52e-0316882IPR001194
DomainLaminin_G

CNTNAP3B FAT3 CNTNAP3

2.59e-0358883IPR001791
DomainUSP_CS

USP32 USP9Y USP33

3.73e-0366883IPR018200
DomainConA-like_dom

CNTNAP3B FAT3 CNTNAP3 HNRNPUL1 RYR2

3.77e-03219885IPR013320
DomainFA58C

CNTNAP3B CNTNAP3

4.35e-0321882SM00231
DomainFA58C_3

CNTNAP3B CNTNAP3

4.35e-0321882PS50022
DomainFA58C_1

CNTNAP3B CNTNAP3

4.35e-0321882PS01285
DomainFA58C_2

CNTNAP3B CNTNAP3

4.35e-0321882PS01286
DomainUSP_1

USP32 USP9Y USP33

4.41e-0370883PS00972
DomainUCH

USP32 USP9Y USP33

4.59e-0371883PF00443
DomainUSP_2

USP32 USP9Y USP33

4.59e-0371883PS00973
DomainEF_HAND_2

CAPN8 CABP5 PPP3R1 USP32 RYR2

4.72e-03231885PS50222
DomainUSP_3

USP32 USP9Y USP33

4.77e-0372883PS50235
DomainUSP_dom

USP32 USP9Y USP33

4.77e-0372883IPR028889
DomainPeptidase_C19_UCH

USP32 USP9Y USP33

4.77e-0372883IPR001394
DomainEF_hand_dom

CAPN8 CABP5 PPP3R1 USP32 RYR2

4.81e-03232885IPR002048
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

TRIM66 WIZ SUGP2 SH3TC1 MTHFR FAT3 SMARCA1 QTRT2 DDX56 CSMD1 KIF18B DNA2 PCCA ANKRD52 CREBBP

2.01e-071116911531753913
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

RAB10 ARRB2 DENND1B SUGP2 SH3TC1 TBC1D1 XPNPEP3 TBC1D14 SPACA6 DDX56 CACNA1H PRKD1 CHD6 CSMD1 PCCA CREBBP HPS3

2.84e-071489911728611215
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

TET2 TRIM66 WIZ PPP3R1 RTRAF USP32 ARFGEF2 CHD6 ADAMTS8 HNRNPUL1 USP9Y CREBBP SLC4A3 ARCN1 USP33

1.19e-061285911535914814
Pubmed

HIV latency. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection.

C2CD3 HNRNPUL1 CREBBP

3.75e-061291325011556
Pubmed

MTHFR C677T, MTHFR A1298C, and OPG A163G polymorphisms in Mexican patients with rheumatoid arthritis and osteoporosis.

MTHFR TNFRSF11B

6.77e-06291222377704
Pubmed

Osteoprotegerin and MTHFR gene variations in rheumatoid arthritis: association with disease susceptibility and markers of subclinical atherosclerosis.

MTHFR TNFRSF11B

6.77e-06291235680906
Pubmed

Deubiquitinase USP33 promotes the glycolysis and growth of osteosarcoma by modifying PFKFB3 ubiquitination and degradation.

PFKFB3 USP33

6.77e-06291237034227
Pubmed

Caspr3-Deficient Mice Exhibit Low Motor Learning during the Early Phase of the Accelerated Rotarod Task.

CNTNAP3B CNTNAP3

6.77e-06291226807827
Pubmed

Prognostic significance of USP33 in advanced colorectal cancer patients: new insights into β-arrestin-dependent ERK signaling.

ARRB2 USP33

6.77e-06291227835898
Pubmed

MST4 Phosphorylation of ATG4B Regulates Autophagic Activity, Tumorigenicity, and Radioresistance in Glioblastoma.

ATG4B STK26

6.77e-06291229232556
Pubmed

The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice.

CNTNAP3B CNTNAP3

6.77e-06291231150793
Pubmed

Stomach-specific calpain, nCL-2, localizes in mucus cells and proteolyzes the beta-subunit of coatomer complex, beta-COP.

CAPN8 ARCN1

6.77e-06291216476741
Pubmed

β-Arrestin-Dependent Dopaminergic Regulation of Calcium Channel Activity in the Axon Initial Segment.

ARRB2 CACNA1H

6.77e-06291227452469
Pubmed

Identification of androgen-selective androgen-response elements in the human aquaporin-5 and Rad9 genes.

AQP5 RAD9A

6.77e-06291218215141
Pubmed

TET2 and CSMD1 genes affect SBP response to hydrochlorothiazide in never-treated essential hypertensives.

TET2 CSMD1

6.77e-06291225695618
Pubmed

Co-regulated pendrin and aquaporin 5 expression and trafficking in Type-B intercalated cells under potassium depletion.

SLC26A4 AQP5

6.77e-06291224429825
Pubmed

Deubiquitinases and their emerging roles in β-arrestin-mediated signaling.

ARRB2 USP33

2.03e-05391224377933
Pubmed

Sp1 and CREB regulate basal transcription of the human SNF2L gene.

SMARCA1 CREBBP

2.03e-05391218243132
Pubmed

The deubiquitinases USP33 and USP20 coordinate beta2 adrenergic receptor recycling and resensitization.

ARRB2 USP33

4.05e-05491219424180
Pubmed

Beta-arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2.

ARRB2 USP33

4.05e-05491219363159
Pubmed

HIV/AIDS. Persistence by proliferation?

C2CD3 HNRNPUL1 CREBBP

4.31e-052691325013050
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

ATG4B ARRB2 SUGP2 EML4 SMARCA1 DDX56 DGKD LTF HNRNPUL1 KIF18B ANKRD52 CREBBP ARCN1

5.04e-051353911329467282
Pubmed

Expression of aquaporin 1 and 5 in the developing mouse inner ear and audiovestibular assessment of an Aqp5 null mutant.

SLC26A4 AQP5

6.74e-05591212943377
Pubmed

Novel roles of TLR3 tyrosine phosphorylation and PI3 kinase in double-stranded RNA signaling.

TLR3 CREBBP

6.74e-05591215502848
Pubmed

ROS inhibits RORα degradation by decreasing its arginine methylation in liver cancer.

RORA CREBBP

6.74e-05591236114756
Pubmed

In trans neuregulin3-Caspr3 interaction controls DA axonal bassoon cluster development.

CNTNAP3B CNTNAP3

1.01e-04691234143959
Pubmed

Gene polymorphisms and osteoporotic fractures: a study in postmenopausal French women.

MTHFR TNFRSF11B

1.01e-04691219299182
Pubmed

Crystal structure of EML1 reveals the basis for Hsp90 dependence of oncogenic EML4-ALK by disruption of an atypical β-propeller domain.

EML4 EML1

1.01e-04691224706829
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

TET2 ARRB2 WIZ ATG2B CHD6 PCCA ANKRD52

1.17e-0441891734709266
Pubmed

Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors.

RAB10 DENND4A DENND1B

1.26e-043791320937701
Pubmed

MARCH2 promotes endocytosis and lysosomal sorting of carvedilol-bound β(2)-adrenergic receptors.

ARRB2 USP33

1.41e-04791223166351
Pubmed

Microtubule association of EML proteins and the EML4-ALK variant 3 oncoprotein require an N-terminal trimerization domain.

EML4 EML1

1.41e-04791225740311
Pubmed

Ca(2+)-binding proteins in the retina: from discovery to etiology of human disease(1).

CABP5 PPP3R1

1.41e-04791211108966
Pubmed

Functional proteomics mapping of a human signaling pathway.

ARRB2 TBC1D1 ARFGEF2 CHD6 HNRNPUL1 CCDC181 CREBBP RYR2

1.64e-0459191815231748
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

RAB10 SLC9C1 DENND4A EML4 TBC1D1 XPNPEP3 ATG2B QTRT2 PRKD1 HNRNPUL1 KIF18B CREBBP

1.70e-041321911227173435
Pubmed

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.

PIK3AP1 TBC1D14 PRKD1 CSMD1 RYR2

1.82e-0419991523382691
Pubmed

Downregulation of ten-eleven translocation-2 triggers epithelial differentiation during organogenesis.

TET2 AQP5

1.88e-04891235569195
Pubmed

Atoh1-lineal neurons are required for hearing and for the survival of neurons in the spiral ganglion and brainstem accessory auditory nuclei.

ACAN RORA

1.88e-04891219741118
Pubmed

DNA methyltransferase 3b regulates articular cartilage homeostasis by altering metabolism.

TET2 ACAN

1.88e-04891228614801
Pubmed

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.

C2CD3 SUGP2 RTRAF PRKD1 HNRNPUL1 DNA2 RYR2

2.16e-0446291731138677
Pubmed

Molecular determinants of response kinetics of mouse M1 intrinsically-photosensitive retinal ganglion cells.

ARRB2 RGS2

2.41e-04991234873237
Pubmed

Toll-like receptors differentially regulate GPCR kinases and arrestins in primary macrophages.

ARRB2 TLR3

2.41e-04991218180038
Pubmed

Interaction of TAGLN and USP1 promotes ZEB1 ubiquitination degradation in UV-induced skin photoaging.

USP32 USP9Y

2.41e-04991237149635
Pubmed

Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.

WIZ SUGP2 STK26 ATG2B ARFGEF2

2.60e-0421591535973513
Pubmed

Cav3.2 T-type calcium channel is required for the NFAT-dependent Sox9 expression in tracheal cartilage.

ACAN CACNA1H

3.01e-041091224778262
Pubmed

SUMOylation of pontin chromatin-remodeling complex reveals a signal integration code in prostate cancer cells.

RORA CREBBP

3.01e-041091218087039
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

DENND4A USP32 ATG2B ARFGEF2 ARMCX3 HPS3 USP33

3.65e-0450491734432599
Pubmed

Loss of betaarrestin1 and betaarrestin2 contributes to pulmonary hypoplasia and neonatal lethality in mice.

ARRB2 AQP5

5.18e-041391220060823
Pubmed

Genome-wide SNP associations with rubella-specific cytokine responses in measles-mumps-rubella vaccine recipients.

RNASE9 SLC4A3

6.04e-041491224811271
Pubmed

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.

TET2 WIZ MTMR14 RTRAF XPNPEP3 PFKFB3 HNRNPUL1

6.20e-0455191734728620
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

C2CD3 WIZ SUGP2 MTMR14 SH3TC1 MTHFR ARFGEF2 DDX56 CACNA1H RAD9A

6.31e-041105911035748872
Pubmed

Defining epithelial cell dynamics and lineage relationships in the developing lacrimal gland.

LTF AQP5

8.98e-041791228576768
Pubmed

Cell adhesion molecule contactin-associated protein 3 is expressed in the mouse basal ganglia during early postnatal stages.

CNTNAP3B CNTNAP3

8.98e-041791226389685
Pubmed

Calcium handling precedes cardiac differentiation to initiate the first heartbeat.

CACNA1H RYR2

8.98e-041791227725084
Pubmed

Loss of bone sialoprotein leads to impaired endochondral bone development and mineralization.

ACAN TNFRSF11B

8.98e-041791225464126
Pubmed

BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.

DENND4A WIZ MTMR14 USP32 USP33

9.34e-0428591534369648
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

WIZ SUGP2 ARFGEF2 HNRNPUL1 PCCA ARMCX3 ARCN1 RYR2

9.97e-0477791835844135
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

STK26 ATG2B SMARCA1 DNA2 ANKRD52 ARMCX3 ARCN1

1.08e-0360691736538041
Pubmed

Follow-up examination of linkage and association to chromosome 1q43 in multiple sclerosis.

RGS2 RYR2

1.25e-032091219626040
Pubmed

Ectodysplasin-A signaling is a key integrator in the lacrimal gland-cornea feedback loop.

LTF AQP5

1.38e-032191231221639
Pubmed

FoxP1 orchestration of ASD-relevant signaling pathways in the striatum.

CNTNAP3B CNTNAP3

1.51e-032291226494785
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

RAB10 C2CD3 ARRB2 ATG2B CHD6 KIF18B CREBBP

1.54e-0364591725281560
Pubmed

Genomic variants in an inbred mouse model predict mania-like behaviors.

HPS3 DNAH11

1.65e-032391229768498
Pubmed

Snf2h-mediated chromatin organization and histone H1 dynamics govern cerebellar morphogenesis and neural maturation.

SMARCA1 CREBBP

1.80e-032491224946904
Pubmed

Avoiding mouse traps in schizophrenia genetics: lessons and promises from current and emerging mouse models.

PPP3R1 MTHFR

1.80e-032491221821099
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

RAB10 DENND4A ATG4B ARRB2 EML4 DDX56 LTF PFKFB3 HNRNPUL1 RGS2

1.94e-031284911017353931
Pubmed

Essential pro-Bmp roles of crossveinless 2 in mouse organogenesis.

ACAN AQP5

1.95e-032591217035289
Pubmed

The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors.

ARRB2 SLC26A4 TNFRSF11B

2.27e-039991319730683
Pubmed

In Vitro Identification of Histatin 5 Salivary Complexes.

PIK3AP1 LTF

2.28e-032791226544073
Pubmed

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

CHD6 CREBBP

2.28e-032791217525332
Pubmed

β-catenin activity in late hypertrophic chondrocytes locally orchestrates osteoblastogenesis and osteoclastogenesis.

ACAN TNFRSF11B

2.28e-032791227621061
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

ACAN ATG2B DGKD CACNA1H PFKFB3 HNRNPUL1

2.32e-0351391625798074
Pubmed

Genetic association with overall survival of taxane-treated lung cancer patients - a genome-wide association study in human lymphoblastoid cell lines followed by a clinical association study.

SEZ6L2 RYR2

2.45e-032891223006423
Pubmed

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.

WIZ SMARCA1 DDX56

2.54e-0310391332744500
GeneFamilyHelix-turn-helix CENPB type domain containing

TIGD7 TIGD2

1.09e-0313692533
GeneFamilyUbiquitin specific peptidases

USP32 USP9Y USP33

1.28e-0356693366
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

ACAN CSMD1 SEZ6L2

1.34e-03576931179
GeneFamilyEF-hand domain containing

CAPN8 CABP5 PPP3R1 USP32 RYR2

1.49e-03219695863
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP42 CNTNAP3B ACAN SLC26A4 CNTNAP3 DGKD SLC4A3

1.24e-0718991778cf414b98bcb19deb934409acddaad1cd51b67f
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CNTNAP3B CNTNAP3 LTF EML1 EPB41L4A TNFRSF11B

1.23e-06167916d7fe24cdc4b55a9555ce9e20699f5036b88148e9
ToppCellhuman_hepatoblastoma-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

TET2 CNTNAP3B XIRP2 CNTNAP3 DNAI3 RYR2

1.84e-0617991614fc8ccb6b215063d747643f47d780d2b237eb67
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP42 CNTNAP3B SLC26A4 CNTNAP3 DGKD DNAI3

1.96e-06181916bd7e9437839bca543ca5945df43d6525e6a312a8
ToppCellCOVID-19_Mild-gd_T|COVID-19_Mild / Disease condition and Cell class

PIK3AP1 DGKD RORA EPB41L4A RGS2 CD160

2.09e-06183916f593a89b0aa8fffdfa403769916facfd30358521
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP42 CNTNAP3B ACAN SLC26A4 CNTNAP3 DGKD

2.09e-0618391604d3cc76038b8192c915f1c08c3e26f2ad3b3779
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPN8 XIRP2 FAT3 CSMD1 RYR2 DNAH11

2.15e-061849162cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPN8 XIRP2 FAT3 CSMD1 RYR2 DNAH11

2.15e-06184916ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPN8 XIRP2 FAT3 CSMD1 RYR2 DNAH11

2.15e-061849162b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP42 CNTNAP3B ACAN SLC26A4 CNTNAP3 DGKD

2.29e-06186916948815663c212c4311329d503b5991cbbbff9808
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP42 CNTNAP3B ACAN SLC26A4 CNTNAP3 DGKD

2.44e-061889168de5a07301f9b5984680c873e5a92395b5ed3dd3
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP42 CNTNAP3B ACAN SLC26A4 CNTNAP3 DGKD

2.59e-061909163f22c118d552345f731d4d49f0bcb5765d93de3b
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP42 CNTNAP3B ACAN SLC26A4 CNTNAP3 DGKD

2.59e-0619091639ab890104b4264c68a968f920f4ccd84f0bc681
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP42 CNTNAP3B ACAN SLC26A4 CNTNAP3 DGKD

2.59e-061909160acf1d5da68db449d8c9e70519a236ce825f9d11
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP42 CNTNAP3B ACAN SLC26A4 CNTNAP3 DGKD

2.59e-06190916e58e4b6fbeb4368f738adac67ec10879c0966f0f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP42 CNTNAP3B ACAN SLC26A4 CNTNAP3 DGKD

2.84e-06193916c4b22b62f3cc7bf0ec0eba76e1504c236290bbc9
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

PIK3AP1 ARRB2 SH3TC1 TBC1D14 PFKFB3 RGS2

2.92e-06194916663e7e7fe48157e808b4f1a0ea6ad41944e857a2
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-WFDC2--L2-4|Neuronal / cells hierarchy compared to all cells using T-Statistic

ARHGAP42 CNTNAP3B ACAN SLC26A4 CNTNAP3 DGKD

3.48e-06200916c65e6336725856c4b5f6aeba1cf86a23ec815d34
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-WFDC2-|Neuronal / cells hierarchy compared to all cells using T-Statistic

ARHGAP42 CNTNAP3B ACAN SLC26A4 CNTNAP3 DGKD

3.48e-06200916117a25b3b9cdbc2e198381350a8362bee25e82e7
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-WFDC2|Neuronal / cells hierarchy compared to all cells using T-Statistic

ARHGAP42 CNTNAP3B ACAN SLC26A4 CNTNAP3 DGKD

3.48e-06200916d459e51507bf26865e6e7e04411379ec82a3edf8
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TET2 ARRB2 ARFGEF2 LTF RAB44

7.94e-06133915f6e9a1301a3379847b215303a9b0c028841e2cc0
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TET2 ARRB2 ARFGEF2 LTF RAB44

7.94e-06133915292ecfcadbaf15e0d34a3ab9bf511ab1065888bd
ToppCell3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

CAPN8 DENND1B EML4 CNTNAP3 RORA

8.54e-06135915ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 MTHFR TBC1D1 ADAMTS8 CSMD1

2.06e-05162915c7114e24cb5525abb9780ca3d35dbcc4eabd4b64
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 MTHFR TBC1D1 ADAMTS8 CSMD1

2.06e-05162915f1851a173d3bcca2981d934161ec85d1cc0af5a2
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 MTHFR TBC1D1 ADAMTS8 CSMD1

2.06e-051629155d902bb31e691aea9749617cc88303c2448f24b8
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LRRIQ1 CCDC181 DNAI3 SEZ6L2 DNAH11

2.45e-051689159a8709d34865cfa668d8f3335dc34fc86fc32482
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT3 ATP13A5 LTF RYR2 DNAH11

2.52e-0516991512bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellfacs-Marrow-T-cells-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3TC1 TLR3 USP9Y DNA2 HPS3

2.60e-05170915a78d9789c3e7c84a36e1bd380192d7aba4a4d443
ToppCellASK428-Epithelial-Secretory|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

CAPN8 ATP13A5 LTF EPB41L4A AQP5

2.60e-051709159e275c4a70f9866f770fbdb0fe14a577287fe290
ToppCellfacs-Marrow-T-cells-3m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3TC1 TLR3 USP9Y DNA2 HPS3

2.60e-05170915ff68600b945b3a5437b14e5411b3db800d0ccbe5
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND1B ASIC1 EPB41L4A SLC4A3 RGS2

2.75e-051729153f784aed340b50ddbec3f7dc0a5279180d38a2bb
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3B SLC26A4 CNTNAP3 DGKD SLC4A3

3.07e-05176915682a1dfcc507ec540f5fadf08e872533ea9f0291
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND1B ASIC1 TBC1D1 EPB41L4A SLC4A3

3.07e-051769155e46a09a36b9645b1b1fcb0b64bd0898561af3a9
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L1-3_PVALB_WFDC2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP42 CNTNAP3B SLC26A4 CNTNAP3 DGKD

3.15e-05177915c20df760b25caa772278397b02fc36521927cbfc
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND1B ASIC1 TBC1D1 EPB41L4A SLC4A3

3.15e-0517791514fb8d182775dfd0e49aa7e4e12543a85b3b8bd6
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP42 CNTNAP3B SLC26A4 CNTNAP3 DGKD

3.24e-051789156ad46b0720298bcb927fd53468bb4ea0c199ad35
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TBC1D1 SLC26A4 TBC1D14 RORA DNAH11

3.41e-05180915cfc8bfbfd3617aabbb49f9730c29b673ca157e74
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP42 CNTNAP3B ACAN CNTNAP3 DGKD

3.41e-051809158f774dcacc1626e4e6492f1eb927b0ed56fbe686
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CNTNAP3B CNTNAP3 EML1 EPB41L4A TNFRSF11B

3.41e-0518091527e8bbee388e64dd79d70b160b76d45b1f398006
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3AP1 LRRIQ1 PFKFB3 TNFRSF11B DNAH11

3.50e-051819156a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
ToppCellCOVID-19-Epithelial-Ionocytes|Epithelial / Condition, Lineage and Cell class

SLC9C1 SH3TC1 TBC1D1 CACNA1H PDE11A

3.50e-051819154a8d4f2709c1b25f908867f1b2fae1d2d0abf1d4
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TET2 ARRB2 MTMR14 PFKFB3 RGS2

3.60e-05182915dc32f8f6a3b13918eb8e93c018f5823d86344080
ToppCellCOVID-19-Heart-CM_3|Heart / Disease (COVID-19 only), tissue and cell type

SLC9C1 XIRP2 DGKD TNFRSF11B RYR2

3.60e-05182915287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP42 CNTNAP3B SLC26A4 CNTNAP3 DGKD

3.69e-05183915121791ef84e7ce377ed6f5b7953af8865e04958e
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP42 CNTNAP3B SLC26A4 CNTNAP3 DGKD

3.79e-051849152ba98708dfd7f1b2a661578a334684094ff453ad
ToppCellCV-Healthy-7|CV / Virus stimulation, Condition and Cluster

TIGD7 DENND1B XPNPEP3 TLR3 ZMYM6

3.79e-051849150e5cc77aaa73ceb791f8be7456177577fd2e5586
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 TRABD2B MTHFR RORA RYR2

3.79e-05184915d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCellCV-Healthy-7|Healthy / Virus stimulation, Condition and Cluster

TIGD7 DENND1B XPNPEP3 TLR3 ZMYM6

3.89e-051859151979d189c204f4c2893e3170a514ee7d5523406c
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L1-3_PVALB_WFDC2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3B ACAN SLC26A4 CNTNAP3 DGKD

3.89e-05185915e87e6e097dc29ece8aea671935bde281b99b93ea
ToppCellPCW_07-8.5-Endothelial-Endothelial_mature-lymphatic|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CNTNAP3B SH3TC1 SLC26A4 CNTNAP3 LTF

3.99e-051869155d94e6dd2c92e0c46badeb1e6eb54b69af855a66
ToppCellPCW_07-8.5-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CNTNAP3B SH3TC1 SLC26A4 CNTNAP3 LTF

3.99e-051869151da52e13096dfe4eb08bd0e7461cb3809b3b3deb
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP42 CNTNAP3B SLC26A4 CNTNAP3 DGKD

3.99e-051869156379609b7ace80683f5754b16aa77f11b43766ae
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP42 CNTNAP3B SLC26A4 CNTNAP3 DGKD

4.09e-05187915d413fb4b1531b297af5012a392b88128510c2de8
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein|Children_(3_yrs) / Lineage, Cell type, age group and donor

CNTNAP3B CNTNAP3 EML1 EPB41L4A TNFRSF11B

4.09e-05187915e35716f8b482be3bf5ab79f087a9caf67a9d197a
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

FAT3 RORA PRKD1 ADAMTS8 RYR2

4.09e-0518791592d468dde81125d51daf7abd4703741abe1ab91c
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP42 SLC9C1 TRABD2B FAT3 RYR2

4.20e-051889153177b2c1723268d330d3e9f24f9e24492ace6286
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3AP1 FAT3 PFKFB3 TNFRSF11B DNAH11

4.31e-05189915904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT3 PRKD1 ADAMTS8 DNAI3 RYR2

4.31e-051899152a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3B SLC26A4 CNTNAP3 DGKD SLC4A3

4.41e-0519091526843ec1d19ac85a50990705353b802745d33e4d
ToppCellControl-Myeloid-Transitioning_MDM|Control / group, cell type (main and fine annotations)

TET2 ARRB2 SH3TC1 PFKFB3 RGS2

4.41e-05190915d6fd8c23cde4a10cc1517b6899a5a855fdfff2e2
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP42 CNTNAP3B SLC26A4 CNTNAP3 DGKD

4.41e-05190915305fbef734c350cfbf786ca7ff6e07093aab56ea
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP42 ACAN CACNA1H CSMD1 RYR2

4.41e-0519091573d94fbae92029745989a8712eed8b99fd84c193
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARHGAP42 ACAN CACNA1H CSMD1 RYR2

4.41e-05190915d6b3a92119b210974a32af3fe9875d60eb02761e
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP42 CNTNAP3B SLC26A4 CNTNAP3 DGKD

4.41e-051909158c9c230a509afaeee50644153974a5642b01a2b8
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

EML4 FAT3 RORA ADAMTS8 RYR2

4.53e-0519191508720998aa55131d7377c4c67c4c935865bd7d79
ToppCellMesenchymal-vascular_smooth_muscle_cell|World / Lineage, Cell type, age group and donor

ARHGAP42 ACAN CACNA1H CSMD1 RYR2

4.53e-05191915fd89fbc62aa1c73e0f659991e3bd726a0c97bd68
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FAT3 RORA PRKD1 ADAMTS8 RYR2

4.53e-051919156688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FAT3 RORA PRKD1 ADAMTS8 RYR2

4.64e-0519291599ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP42 FAT3 PRKD1 ADAMTS8 RYR2

4.64e-051929153d0cb19f037f604253d7d728689aeaa94251e92b
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP42 CNTNAP3B SLC26A4 CNTNAP3 DGKD

4.64e-051929150003d7ef9a8e521e70ac33c63aad843d9b6215c2
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT3 PRKD1 ADAMTS8 DNAI3 RYR2

4.64e-05192915deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAT3 RORA PRKD1 ADAMTS8 RYR2

4.76e-0519391599525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAT3 RORA PRKD1 ADAMTS8 RYR2

4.76e-05193915b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCellFetal_29-31_weeks-Immune-alveolar_macrophage_(MARCO_positive)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PIK3AP1 ARRB2 SH3TC1 TBC1D14 PFKFB3

4.87e-051949153043f6230fa723037c8cf7123f611ae847b39fd4
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAT3 RORA PRKD1 ADAMTS8 RYR2

4.87e-05194915e93de9428c986b8943fc169258847c650cfab0e5
ToppCellLPS-antiTNF-Stromal_mesenchymal|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP42 FAT3 PRKD1 ADAMTS8 RYR2

4.87e-051949156e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRRIQ1 SLC26A4 CCDC181 DNAI3 DNAH11

4.99e-05195915d211a836cf711fdb91b10d512f09d462be937cc5
ToppCellCOVID-19-lung-Macrophage_CD163hi_MERTKhi|lung / Disease (COVID-19 only), tissue and cell type

PIK3AP1 TET2 ARRB2 SH3TC1 TBC1D14

4.99e-05195915148fff8c3c9ba45ec36e98dff1be57e3f8294506
ToppCellChildren_(3_yrs)-Immune-monocyte-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PIK3AP1 ARRB2 TBC1D1 PFKFB3 RGS2

4.99e-0519591581a28289eda1a8a1a31b7357106f64ac5000e172
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

FAT3 RORA PRKD1 ADAMTS8 RYR2

4.99e-05195915603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCellControl-Lymphoid-T|Lymphoid / Disease state, Lineage and Cell class

SH3TC1 EML4 RORA PFKFB3 RYR2

4.99e-051959156687e579582d7a239bee80846de0cf827a6f6a62
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CAPN8 ARHGAP42 SLC26A4 EPB41L4A AQP5

4.99e-05195915e7230a849ea31e6eef9bc6f5468938499450582d
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D122|Adult / Lineage, Cell type, age group and donor

FAT3 RORA PRKD1 ADAMTS8 RYR2

4.99e-05195915aa0add081881d349099d12efca5cdee098038d4e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CAPN8 SLC9C1 DENND1B FAT3 PFKFB3

5.12e-05196915c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCell367C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ARRB2 EML4 RORA PFKFB3 HNRNPUL1

5.12e-05196915e38036a5dbaed1488e01616bdc7678b28968470b
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_EM-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TRIM66 ASTE1 EID2B CCDC181 DNAH11

5.12e-051969157e98380d815fbf6254289ace2af37aac6fef51e8
ToppCellIPF-Lymphoid-T|Lymphoid / Disease state, Lineage and Cell class

SH3TC1 EML4 RORA PFKFB3 RYR2

5.12e-051969156e70c48a63d9673eb16b0847c1bd88eecc2f7a3c
ToppCellCOPD-Lymphoid-T|Lymphoid / Disease state, Lineage and Cell class

SH3TC1 EML4 RORA PFKFB3 RYR2

5.12e-05196915c9bdd505c3ab380ed7b272aa518df31a0a706a06
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CPSF4L TRABD2B TBC1D1 CACNA1H RYR2

5.37e-05198915f261a37dd07976548b897af86df1d1a0dc069889
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PIK3AP1 SLC26A4 LTF PFKFB3 RGS2

5.37e-05198915963f028bf5491fa2b38982828a32ab96dcc34bf4
ToppCellCOPD-Myeloid-Macrophage|Myeloid / Disease state, Lineage and Cell class

TET2 TBC1D14 PFKFB3 CSMD1 RGS2

5.50e-051999151cf1b2d6debf9e3389f1829dcaa2857e9533a080
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TBC1D1 ACAN CACNA1H ADAMTS8 RYR2

5.50e-05199915c2903b1a4b91e94bbdaa909bacefe901255cf248
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intravascular|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PIK3AP1 ARRB2 SH3TC1 TBC1D14 RGS2

5.63e-05200915179afc4bee7a2fd85a3b5dadf32544a63807c164
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)|Neuronal / cells hierarchy compared to all cells using T-Statistic

ARHGAP42 CNTNAP3B SLC26A4 CNTNAP3 DGKD

5.63e-052009151276bfa911fddada4235e12e3081baa53164574b
ToppCellChildren_(3_yrs)-Immune-monocyte-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

PIK3AP1 TET2 ARRB2 SH3TC1 TBC1D14

5.63e-05200915881ab995c90d75fd987d6e8f1f926a4bfcc4235f
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PIK3AP1 ARRB2 SH3TC1 TBC1D14 RGS2

5.63e-05200915ad52b38df5c71f28829b04cd0e6b97f0f9f7610a
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ARHGAP42 ACAN DGKD ADAMTS8 RYR2

5.63e-052009154e1e19214aeebbdca004de7faaf4cc9d18498591
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-BMP_responsible_cell|6m / Sample Type, Dataset, Time_group, and Cell type.

LRRIQ1 CCDC181 EPB41L4A DNAI3 PDE11A

5.63e-052009155fb90118d3abc28d72bc483e68317255090a04c7
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_submucosal-gland|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CAPN8 PRKD1 LTF AQP5 PDE11A

5.63e-0520091568b0f987c4fb8078675475f4f1e71302f832ef69
Diseasebrain connectivity measurement

LRRIQ1 DENND1B TIGD2 FAT3 ADAMTS8 EML1 PCCA TNFRSF11B

2.66e-05400888EFO_0005210
DiseaseDuchenne muscular dystrophy (implicated_via_orthology)

CAPN8 EML4 EML1

1.70e-0436883DOID:11723 (implicated_via_orthology)
DiseaseMastocytosis

ARHGAP42 TRABD2B CACNA1H

2.17e-0439883EFO_0009001
Diseaseautosomal recessive intellectual developmental disorder (implicated_via_orthology)

CNTNAP3B CNTNAP3

2.43e-048882DOID:0060308 (implicated_via_orthology)
Diseasecortical surface area measurement, neuroimaging measurement

SLC25A20 FAT3 RORA EML1 DNAH11

6.01e-04227885EFO_0004346, EFO_0010736
Diseasetriacylglycerol 52:1 measurement

RORA CSMD1

7.82e-0414882EFO_0010413
Diseasediastolic blood pressure, systolic blood pressure

C2CD3 DENND1B TBC1D1 ACAN CHD6 ADAMTS8 RYR2 PDE11A

8.84e-04670888EFO_0006335, EFO_0006336
DiseaseLymphoma, Follicular, Grade 2

MTHFR CREBBP

9.00e-0415882C1956132
DiseaseLymphoma, Follicular, Grade 3

MTHFR CREBBP

9.00e-0415882C1956131
DiseaseLymphoma, Follicular, Grade 1

MTHFR CREBBP

9.00e-0415882C1956130
Diseasemyelodysplastic syndrome (implicated_via_orthology)

TET2 CREBBP

9.00e-0415882DOID:0050908 (implicated_via_orthology)
DiseaseLymphoma, Large-Cell, Follicular

MTHFR CREBBP

9.00e-0415882C0079745
DiseaseLymphoma, Small Cleaved-Cell, Follicular

MTHFR CREBBP

9.00e-0415882C0079765
DiseaseLymphoma, Mixed-Cell, Follicular

MTHFR CREBBP

9.00e-0415882C0079758
Diseaselipid metabolism disorder (implicated_via_orthology)

SLC25A20 MTHFR

9.00e-0415882DOID:3146 (implicated_via_orthology)
Diseaseautism spectrum disorder (implicated_via_orthology)

CNTNAP3B CNTNAP3 CHD6 CREBBP

1.13e-03152884DOID:0060041 (implicated_via_orthology)
Diseasebrain measurement, neuroimaging measurement

LRRIQ1 DENND1B FAT3 RORA ADAMTS8 EML1 DNAH11

1.30e-03550887EFO_0004346, EFO_0004464
DiseaseLymphoma, Follicular

MTHFR CREBBP

1.61e-0320882C0024301
Diseasecortical thickness

LRRIQ1 DENND1B MTHFR FAT3 ARFGEF2 RORA ADAMTS8 EML1 PCCA RAB44

1.76e-0311138810EFO_0004840
Diseasealcohol drinking

FAT3 SLC26A4 RORA

1.85e-0381883EFO_0004329
Diseasehippocampal volume

TRABD2B EML1 RYR2 PDE11A DNAH11

1.98e-03297885EFO_0005035
Diseaseacute myeloid leukemia (is_implicated_in)

TET2 MTHFR CREBBP

2.05e-0384883DOID:9119 (is_implicated_in)
DiseaseCoronary heart disease

MTHFR DNAH11

2.33e-0324882C0010068
DiseaseProstatic Neoplasms

TET2 MTHFR SLC26A4 SMARCA1 CHD6 ADAMTS8 CREBBP

2.47e-03616887C0033578
DiseaseMalignant neoplasm of prostate

TET2 MTHFR SLC26A4 SMARCA1 CHD6 ADAMTS8 CREBBP

2.47e-03616887C0376358
Diseasebirth weight, parental genotype effect measurement

TET2 MTHFR ARFGEF2 RORA

2.65e-03192884EFO_0004344, EFO_0005939
DiseaseSezary Syndrome

TET2 CREBBP

2.94e-0327882C0036920

Protein segments in the cluster

PeptideGeneStartEntry
EDSLFSEFCDVVRKA

C21orf140

101

B9A014
LLVFEEAFFKFCRAQ

SLC4A3

771

P48751
SDAFKFIVFLACLGV

ATP13A5

396

Q4VNC0
GELTADVCFFFKTTV

CNTNAP3

811

Q9BZ76
GFAIEFKEKPREACF

CSMD1

1551

Q96PZ7
AGLERFTFAFEKDVE

CPSF4L

6

A6NMK7
EEAEGFVVFLCKDRS

CD160

51

O95971
FCRARGRSEFKVFEA

ADAMTS8

626

Q9UP79
DFCEKEFVSALRTFL

ARFGEF2

716

Q9Y6D5
LFAFEEIDGVDVCFF

CREBBP

1396

Q92793
EFDRRLGTIICEAFF

DNAH11

546

Q96DT5
FEPFKDGEFCLRVFS

CAPN8

491

A6NHC0
DKDGDGRISFEEFCA

PPP3R1

141

P63098
RKEAFFCLEFLLDNG

ANKRD52

526

Q8NB46
PIDDFCTKFFVGTEE

DNAI3

626

Q8IWG1
LLCGVRDSEEFLDFF

PIK3AP1

101

Q6ZUJ8
GSLFFFLKEFQVCAD

ARMCX3

331

Q9UH62
DTGKACGVDFEIRAF

ARRB2

136

P32121
FADVVQKFFESLFAC

ASTE1

56

Q2TB18
VAFFTCIEKIDPARF

ATG2B

541

Q96BY7
SIAVGFFCKTEDDFN

ATG4B

316

Q9Y4P1
CSVAFLKAVFAEFLA

AQP5

6

P55064
IRFIEECSFVSDKDA

DENND4A

626

Q7Z401
GKTCVLFRFSDDAFN

RAB10

21

P61026
FFQDCGAKERGFVTR

RAB44

51

Q7Z6P3
TFCLKEFRGLLSFAE

RAD9A

216

Q99638
FEADTFFRFVKACTD

MTHFR

231

P42898
CDFGFARIIGEKSFR

PRKD1

726

Q15139
DRLSKGEEIFFFCFN

MTMR14

381

Q8NCE2
RRFSDLGFEVKCFND

CASP6

76

P55212
LFSFGFEEELKSLLC

DDX56

171

Q9NY93
AFLEFDKDRDGFISC

CABP5

36

Q9NP86
FVEGCKAREAAFDAD

EID2B

121

Q96D98
ECFFIFLDVSRDFVA

FBXW5

471

Q969U6
DADQRLFEAFVIFCG

PDE11A

541

Q9HCR9
FKAFFIESVCDDPTV

PFKFB3

146

Q16875
FDCFRKTLFREGITG

SLC25A20

56

O43772
EFARCLAAEDVVFIG

PCCA

151

P05165
KDLTFVFDRVFGEAA

KIF18B

66

Q86Y91
SFFLEEKLVDNAGFC

LRRIQ1

901

Q96JM4
CFVDRLEGEVFFATR

ACAN

571

P16112
LECIERGVDLFESFF

QTRT2

261

Q9H974
CLFFLKGTEGRERAF

CCDC181

441

Q5TID7
CFLAELLEFAEVIFA

C2CD3

1281

Q4AC94
AIDRFCKPDSDRFVF

CHD6

841

Q8TD26
FFKAEEVIIADFCFL

FAT3

91

Q8TDW7
FQKFDTFRILVCGGD

DGKD

366

Q16760
IGFFDRAVTCIAFSK

EML1

321

O00423
TFERGVGCLDFSKAD

EML4

361

Q9HC35
LFCSFLDEGIVAKFK

GRK1

121

Q15835
KFFQSCADVLAEEGE

FDXACB1

106

Q9BRP7
ERCNILEAFDAFIFA

CACNA1H

131

O95180
FSRKIFDFCIVDEAS

DNA2

751

P51530
FVLTDIESKQRFGFC

DENND1B

71

Q6P3S1
VLGKDCNETSFFFEA

EPB41L4A

261

Q9HCS5
KLEECEEAFTAAFQG

SPACA6

51

W5XKT8
FLRFAVFCNGESVEE

RYR2

2301

Q92736
CFDLIFAFDEIVALG

ARCN1

106

P48444
GELTADVCFFFKTTV

CNTNAP3B

811

Q96NU0
DKFAENDVIGCFADF

HNRNPUL1

321

Q9BUJ2
GFNCKDETEFRNFIV

RTRAF

16

Q9Y224
AFRAFLKSEFCEENI

RGS2

96

P41220
ICFVGDKDARAAFIR

SMARCA1

261

P28370
AKVVTFDCGNDIFEE

SLC9C1

886

Q4G0N8
FRCLAENAGDVAFVK

LTF

551

P02788
DALFVAAGCKVEAFA

HPS3

31

Q969F9
DKRFCFDIEVVERHG

ARHGAP42

336

A6NI28
GDFTKSFKEFIDACL

STK26

241

Q9P289
IFLNEEEKSFFSEGC

SH3TC1

376

Q8TE82
EFCGEFFENRKGLSS

WIZ

1046

O95785
KEEFEECLEKFFSTG

RNASE9

41

P60153
FEAFEEDRCFAPFLA

SEZ6L2

456

Q6UXD5
GEVCSAEDFKVVFTR

ASIC1

176

P78348
VFCRDGEEFLFRTAL

TBC1D14

606

Q9P2M4
DVRKGCFIFETFSLD

XIRP2

1096

A4UGR9
AAREFCGSFQEFVEK

TIGD2

151

Q4W5G0
GIDVTLCEEAFFRFA

TNFRSF11B

196

O00300
LCEEAFFRFAVPTKF

TNFRSF11B

201

O00300
FCLEERDFEAGVFEL

TLR3

786

O15455
CGFFDDNIRKDTFFL

SLC26A4

706

O43511
FKSLGCEDFISFVFE

RORA

391

P35398
CEDFISFVFEFGKSL

RORA

396

P35398
RENEDKICFFAFGAG

TRABD2B

316

A6NFA1
FDIIDKSDVFSRFGI

SUGP2

316

Q8IX01
DDTFSKKFEVLFCGR

TBC1D1

166

Q86TI0
DVKSEACQRFFRDGL

USP9Y

111

O00507
SEVCKFLSARDFGER

ZMYM6

496

O95789
FLYAKFEFECRARGA

XPNPEP3

281

Q9NQH7
DSEVAEAGRCLEVFF

TRIM66

1126

O15016
REGSFFGQTKVEECF

TET2

771

Q6N021
AAERFARCFGRTDFK

TIGD7

106

Q6NT04
FCFKVFDVDRDGVLS

USP32

271

Q8NFA0
DCLAAFFARDELKGD

USP33

571

Q8TEY7