Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionfatty acid omega-hydroxylase activity

CYP4V2 CYP4F2 CYP4F3 CYP4F11

1.26e-07101014GO:0120250
GeneOntologyMolecularFunctionlong-chain fatty acid omega-hydroxylase activity

CYP4V2 CYP4F2 CYP4F3 CYP4F11

1.26e-07101014GO:0102033
GeneOntologyMolecularFunctionalpha-tocopherol omega-hydroxylase activity

CYP4F2 CYP4F3 CYP4F11

1.25e-0651013GO:0052871
GeneOntologyMolecularFunctionleukotriene-B4 20-monooxygenase activity

CYP4F2 CYP4F3 CYP4F11

4.33e-0671013GO:0050051
GeneOntologyMolecularFunctionalkane 1-monooxygenase activity

CYP4F2 CYP4F3 CYP4F11

4.33e-0671013GO:0018685
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

CYP4V2 CYP4Z1 CYP4F2 CYP4F3 CYP4F11

4.79e-06491015GO:0016712
GeneOntologyMolecularFunctionarachidonate epoxygenase activity

CYP4Z1 CYP4F2 CYP4F3 CYP4F11

6.06e-06241014GO:0008392
GeneOntologyMolecularFunctionarachidonate monooxygenase activity

CYP4Z1 CYP4F2 CYP4F3 CYP4F11

9.89e-06271014GO:0008391
GeneOntologyMolecularFunctionarachidonate omega-hydroxylase activity

CYP4F2 CYP4F3 CYP4F11

1.47e-05101013GO:0052869
GeneOntologyMolecularFunction20-hydroxy-leukotriene B4 omega oxidase activity

CYP4F2 CYP4F3

2.53e-0521012GO:0097258
GeneOntologyMolecularFunction20-aldehyde-leukotriene B4 20-monooxygenase activity

CYP4F2 CYP4F3

2.53e-0521012GO:0097259
GeneOntologyMolecularFunctionmonooxygenase activity

CYP4V2 CYP4Z1 CYP4F2 CYP4Z2P CYP4F3 CYP4F11

2.60e-051151016GO:0004497
GeneOntologyMolecularFunctionaromatase activity

CYP4Z1 CYP4F2 CYP4F3 CYP4F11

2.86e-05351014GO:0070330
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen

CYP4F2 CYP4F3 CYP4F11

3.46e-05131013GO:0016713
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

CYP4Z1 CYP4F2 CYP4F3 CYP4F11

4.90e-05401014GO:0016709
GeneOntologyMolecularFunctionL-aspartate:2-oxoglutarate aminotransferase activity

GOT1 GOT2

7.57e-0531012GO:0004069
GeneOntologyMolecularFunctionlipid binding

AGAP5 SNX4 BSPRY SPTBN1 STARD7 CYP4F2 CLEC4F CIDEC AGAP9 AGAP7P AGAP4 CYP4F11 AGAP6 DGAT1 GOT2

1.29e-0498810115GO:0008289
GeneOntologyMolecularFunctionheme binding

CYP4V2 CYP4Z1 CYP4F2 CYP4Z2P CYP4F3 CYP4F11

1.32e-041541016GO:0020037
GeneOntologyMolecularFunctionintracellularly calcium-gated channel activity

CLCA4 CLCA1 ANO3

1.35e-04201013GO:0141147
GeneOntologyMolecularFunctionintracellularly calcium-gated chloride channel activity

CLCA4 CLCA1 ANO3

1.35e-04201013GO:0005229
GeneOntologyMolecularFunctiontetrapyrrole binding

CYP4V2 CYP4Z1 CYP4F2 CYP4Z2P CYP4F3 CYP4F11

1.86e-041641016GO:0046906
GeneOntologyMolecularFunctioniron ion binding

CYP4V2 CYP4Z1 CYP4F2 CYP4Z2P CYP4F3 CYP4F11

1.99e-041661016GO:0005506
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

AGAP5 ELMO1 ARHGEF10L LLGL2 TNK2 PLCG1 AGAP9 AGAP7P AGAP4 AGAP6

2.48e-0450710110GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

AGAP5 ELMO1 ARHGEF10L LLGL2 TNK2 PLCG1 AGAP9 AGAP7P AGAP4 AGAP6

2.48e-0450710110GO:0030695
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

CYP4V2 CYP4Z1 CYP4F2 CYP4Z2P CYP4F3 CYP4F11

4.59e-041941016GO:0016705
GeneOntologyMolecularFunctionGTPase activator activity

AGAP5 ARHGEF10L LLGL2 AGAP9 AGAP7P AGAP4 AGAP6

5.42e-042791017GO:0005096
GeneOntologyMolecularFunctionfructose transmembrane transporter activity

SLC2A7 SLC2A5

8.91e-0491012GO:0005353
GeneOntologyMolecularFunctionchloride channel activity

CLCA4 CLCA1 CLCNKB ANO3

9.53e-04861014GO:0005254
GeneOntologyMolecularFunctioncarboxylic acid binding

CYP4F2 SLC7A6 CYP4F11 GOT1 DGAT1 GOT2

1.36e-032391016GO:0031406
GeneOntologyMolecularFunctionphospholipid binding

AGAP5 SNX4 SPTBN1 CIDEC AGAP9 AGAP7P AGAP4 AGAP6 GOT2

1.84e-035481019GO:0005543
GeneOntologyMolecularFunctionorganic acid binding

CYP4F2 SLC7A6 CYP4F11 GOT1 DGAT1 GOT2

1.85e-032541016GO:0043177
GeneOntologyMolecularFunctionmonoatomic anion channel activity

CLCA4 CLCA1 CLCNKB ANO3

1.86e-031031014GO:0005253
GeneOntologyMolecularFunctionligand-gated monoatomic anion channel activity

CLCA4 CLCA1 ANO3

2.07e-03501013GO:0099095
GeneOntologyMolecularFunctionarachidonate binding

CYP4F2 CYP4F11

2.55e-03151012GO:0050544
GeneOntologyMolecularFunctionicosanoid binding

CYP4F2 CYP4F11

2.90e-03161012GO:0050542
GeneOntologyMolecularFunctionicosatetraenoic acid binding

CYP4F2 CYP4F11

2.90e-03161012GO:0050543
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

CLCA4 CLCA1 CLCNKB ANO3

3.74e-031251014GO:0015108
GeneOntologyBiologicalProcessleukotriene B4 catabolic process

CYP4F2 CYP4F3 CYP4F11

2.12e-066993GO:0036101
GeneOntologyBiologicalProcessleukotriene B4 metabolic process

CYP4F2 CYP4F3 CYP4F11

3.70e-067993GO:0036102
GeneOntologyBiologicalProcessleukotriene catabolic process

CYP4F2 CYP4F3 CYP4F11

5.90e-068993GO:0036100
GeneOntologyBiologicalProcessicosanoid catabolic process

CYP4F2 CYP4F3 CYP4F11

1.72e-0511993GO:1901523
GeneOntologyBiologicalProcessglutamate catabolic process to aspartate

GOT1 GOT2

2.28e-052992GO:0019550
GeneOntologyBiologicalProcesslong-chain fatty acid catabolic process

CYP4F2 CYP4F3 CYP4F11

2.29e-0512993GO:0042758
GeneOntologyBiologicalProcessmenaquinone catabolic process

CYP4F2 CYP4F11

6.82e-053992GO:0042361
GeneOntologyBiologicalProcessaspartate biosynthetic process

GOT1 GOT2

6.82e-053992GO:0006532
GeneOntologyBiologicalProcessaspartate catabolic process

GOT1 GOT2

6.82e-053992GO:0006533
GeneOntologyBiologicalProcessfumarate metabolic process

GOT1 GOT2

6.82e-053992GO:0006106
GeneOntologyBiologicalProcessmenaquinone metabolic process

CYP4F2 CYP4F11

1.36e-044992GO:0009233
GeneOntologyBiologicalProcessphylloquinone metabolic process

CYP4F2 CYP4F11

1.36e-044992GO:0042374
GeneOntologyBiologicalProcessphylloquinone catabolic process

CYP4F2 CYP4F11

1.36e-044992GO:0042376
GeneOntologyBiologicalProcessvitamin K catabolic process

CYP4F2 CYP4F11

1.36e-044992GO:0042377
GeneOntologyBiologicalProcessfatty acid derivative catabolic process

CYP4F2 CYP4F3 CYP4F11

1.55e-0422993GO:1901569
GeneOntologyBiologicalProcessactivation of GTPase activity

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

1.81e-04109995GO:0090630
GeneOntologyBiologicalProcessfatty acid omega-oxidation

CYP4V2 CYP4F2

2.26e-045992GO:0010430
GeneOntologyBiologicalProcessarachidonate metabolic process

CYP4Z1 CYP4F2 CYP4F3 CYP4F11

3.21e-0468994GO:0019369
GeneOntologyBiologicalProcessprostaglandin catabolic process

CYP4F2 CYP4F11

3.38e-046992GO:1905344
GeneOntologyBiologicalProcesslipid droplet fusion

CLSTN3 CIDEC

3.38e-046992GO:0160077
GeneOntologyBiologicalProcessprostanoid catabolic process

CYP4F2 CYP4F11

3.38e-046992GO:0062232
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

CYP4V2 PIGN CLSTN3 CYP4Z1 DOLK SMPD4 HACD4 CYP4F2 EXTL1 HM13 GHRHR NAV3 ATP11A CYP4F3 CYP4F11 TM4SF20 DGAT1

1.98e-04132710117GO:0042175
GeneOntologyCellularComponentapical part of cell

CLCA4 DYNC2H1 SLC2A7 CLDND1 CYP4F2 SLC2A5 CYP4F3 ATP1B2 USH2A CYP4F11

5.86e-0459210110GO:0045177
GeneOntologyCellularComponentapical plasma membrane

CLCA4 SLC2A7 CLDND1 CYP4F2 SLC2A5 CYP4F3 ATP1B2 USH2A CYP4F11

5.89e-044871019GO:0016324
GeneOntologyCellularComponentnuclear outer membrane

SMPD4 GHRHR NAV3

9.50e-04401013GO:0005640
GeneOntologyCellularComponentspecific granule membrane

SLC2A5 PTPRB ATP11A DGAT1

9.94e-04911014GO:0035579
GeneOntologyCellularComponentcell projection membrane

SPTBN1 ACE ADCY6 SLC9C1 BBS7 PLCG1 ATP1B2 USH2A

1.16e-034311018GO:0031253
GeneOntologyCellularComponentendoplasmic reticulum membrane

CYP4V2 PIGN CLSTN3 CYP4Z1 DOLK SMPD4 HACD4 CYP4F2 EXTL1 HM13 ATP11A CYP4F3 CYP4F11 TM4SF20 DGAT1

1.34e-03129310115GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

CYP4V2 PIGN CLSTN3 CYP4Z1 DOLK SMPD4 HACD4 CYP4F2 EXTL1 HM13 ATP11A CYP4F3 CYP4F11 TM4SF20 DGAT1

1.41e-03129910115GO:0098827
MousePhenofused cornea and lens

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

2.54e-0724835MP:0001307
MousePhenoabnormal potassium level

AGAP5 ACE ADCY6 CLCNKB AGAP9 AGAP7P AGAP4 AGAP6

2.08e-05196838MP:0020887
MousePhenoabnormal potassium ion homeostasis

AGAP5 ACE ADCY6 CLCNKB AGAP9 AGAP7P AGAP4 AGAP6

2.24e-05198838MP:0011978
MousePhenoabnormal eye development

PIGN AGAP5 LAMB2 CYP4F2 HM13 CIDEC ATP11A AGAP9 AGAP7P AGAP4 CYP4F11 AGAP6

2.58e-054828312MP:0001286
MousePhenoabnormal vitreous body morphology

PIGN AGAP5 CYP4F2 MALRD1 CIDEC AGAP9 AGAP7P AGAP4 CYP4F11 AGAP6 GOT2

4.42e-054298311MP:0002699
MousePhenoabnormal photoreceptor inner segment morphology

CYP4V2 LAMB2 BBS7 ATP1B2 USH2A

5.08e-0568835MP:0003730
MousePhenopersistence of hyaloid vascular system

AGAP5 CYP4F2 CIDEC AGAP9 AGAP7P AGAP4 CYP4F11 AGAP6

5.22e-05223838MP:0001289
MousePhenoabnormal lens morphology

AGAP5 CYP4F2 PKD1L2 SLC2A5 ATG4B ANAPC1 BBS7 ATP11A AGAP9 AGAP7P AGAP4 CYP4F11 AGAP6 GOT2

5.74e-056998314MP:0001303
MousePhenoabnormal lens development

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

9.82e-0578835MP:0005545
MousePhenoabsent pinna reflex

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

1.83e-0489835MP:0006358
MousePhenoabnormal enzyme/coenzyme level

NCAPD3 AGAP5 SPTBN1 CYP4F2 ACE ADCY6 GHRHR SIDT2 ATG4B CLCNKB ANAPC1 BBS7 CIDEC AGAP9 AGAP7P AGAP4 CYP4F11 AGAP6 ANO3 NR1D2

2.49e-0414518320MP:0005319
MousePhenoabsent kidney

FRAS1 DYNC2H1 HM13 UNK

2.71e-0453834MP:0000520
MousePhenoabnormal pinna reflex

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

3.31e-04101835MP:0001485
MousePhenocornea opacity

AGAP5 TRIM33 AGAP9 AGAP7P AGAP4 AGAP6

3.61e-04159836MP:0001314
MousePhenoabnormal coronary vessel morphology

DYNC2H1 SPTBN1 JARID2 ATP11A

4.10e-0459834MP:0010551
DomainArfGap

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

3.48e-0729965SM00105
DomainArfGap

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

3.48e-0729965PF01412
DomainARFGAP

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

3.48e-0729965PS50115
DomainArfGAP

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

3.48e-0729965IPR001164
DomainCyt_P450_E_grp-I

CYP4V2 CYP4Z1 CYP4F2 CYP4F3 CYP4F11

3.35e-0645965IPR002401
DomainCyt_P450_CS

CYP4V2 CYP4Z1 CYP4F2 CYP4F3 CYP4F11

7.62e-0653965IPR017972
DomainCYTOCHROME_P450

CYP4V2 CYP4Z1 CYP4F2 CYP4F3 CYP4F11

1.09e-0557965PS00086
Domain-

CYP4V2 CYP4Z1 CYP4F2 CYP4F3 CYP4F11

1.19e-05589651.10.630.10
Domainp450

CYP4V2 CYP4Z1 CYP4F2 CYP4F3 CYP4F11

1.19e-0558965PF00067
DomainPH

AGAP5 SPTBN1 ELMO1 PLCG1 AGAP9 AGAP7P AGAP4 AGAP6 SNTB2

1.32e-05278969SM00233
DomainPH_DOMAIN

AGAP5 SPTBN1 ELMO1 PLCG1 AGAP9 AGAP7P AGAP4 AGAP6 SNTB2

1.36e-05279969PS50003
DomainPH_domain

AGAP5 SPTBN1 ELMO1 PLCG1 AGAP9 AGAP7P AGAP4 AGAP6 SNTB2

1.40e-05280969IPR001849
DomainCyt_P450

CYP4V2 CYP4Z1 CYP4F2 CYP4F3 CYP4F11

1.41e-0560965IPR001128
DomainFru_transpt_5

SLC2A7 SLC2A5

2.61e-052962IPR002442
DomainEGF

CNTNAP3B FRAS1 CNTNAP3 LAMB2 CNTNAP5 MALRD1 BRINP2 PROC

2.85e-05235968SM00181
DomainLAM_G_DOMAIN

CNTNAP3B CNTNAP3 CNTNAP5 USH2A

4.23e-0538964PS50025
DomainEGF-like_dom

CNTNAP3B FRAS1 CNTNAP3 LAMB2 CNTNAP5 MALRD1 HMCN2 PROC

4.30e-05249968IPR000742
DomainEGF_1

CNTNAP3B CNTNAP3 LAMB2 CNTNAP5 MALRD1 HMCN2 USH2A PROC

5.09e-05255968PS00022
DomainLaminin_G_2

CNTNAP3B CNTNAP3 CNTNAP5 USH2A

5.20e-0540964PF02210
DomainPH_dom-like

AGAP5 SPTBN1 ELMO1 ARHGEF10L PLCG1 AGAP9 AGAP7P AGAP4 AGAP6 SNTB2

6.73e-054269610IPR011993
DomainLamG

CNTNAP3B CNTNAP3 CNTNAP5 USH2A

7.60e-0544964SM00282
DomainCLCA_chordata

CLCA4 CLCA1

7.82e-053962IPR004727
DomainNHTrfase_class1_PyrdxlP-BS

GOT1 GOT2

7.82e-053962IPR004838
DomainCLCA

CLCA4 CLCA1

7.82e-053962PF08434
DomainCLCA

CLCA4 CLCA1

7.82e-053962IPR013642
DomainAsp_trans

GOT1 GOT2

7.82e-053962IPR000796
DomainConA-like_dom

CNTNAP3B CLSTN3 BSPRY CNTNAP3 CNTNAP5 MALRD1 USH2A

1.36e-04219967IPR013320
DomainFA58C

CNTNAP3B CNTNAP3 CNTNAP5

1.64e-0421963SM00231
DomainFA58C_3

CNTNAP3B CNTNAP3 CNTNAP5

1.64e-0421963PS50022
DomainFA58C_1

CNTNAP3B CNTNAP3 CNTNAP5

1.64e-0421963PS01285
DomainFA58C_2

CNTNAP3B CNTNAP3 CNTNAP5

1.64e-0421963PS01286
DomainLaminin_G

CNTNAP3B CNTNAP3 CNTNAP5 USH2A

2.25e-0458964IPR001791
DomainF5_F8_type_C

CNTNAP3B CNTNAP3 CNTNAP5

2.46e-0424963PF00754
DomainFA58C

CNTNAP3B CNTNAP3 CNTNAP5

2.46e-0424963IPR000421
Domain-

FBXW12 ARHGEF10L LLGL2 WDR6 BBS7 KCTD3 CORO7 CFAP44

3.19e-043339682.130.10.10
DomainWD40/YVTN_repeat-like_dom

FBXW12 ARHGEF10L LLGL2 WDR6 BBS7 KCTD3 CORO7 CFAP44

3.32e-04335968IPR015943
DomainAA_TRANSFER_CLASS_1

GOT1 GOT2

3.87e-046962PS00105
DomainEGF_2

CNTNAP3B CNTNAP3 LAMB2 CNTNAP5 MALRD1 HMCN2 PROC

4.35e-04265967PS01186
DomainFIBRINOGEN_C_1

CNTNAP3B CNTNAP3 CNTNAP5

5.86e-0432963PS00514
DomainFibrinogen_a/b/g_C_dom

CNTNAP3B CNTNAP3 CNTNAP5

5.86e-0432963IPR002181
DomainFIBRINOGEN_C_2

CNTNAP3B CNTNAP3 CNTNAP5

5.86e-0432963PS51406
DomainWD40_repeat_dom

ARHGEF10L LLGL2 WDR6 BBS7 KCTD3 CORO7 CFAP44

8.54e-04297967IPR017986
Domain-

AGAP5 SPTBN1 ELMO1 ARHGEF10L PLCG1 AGAP9 AGAP4 AGAP6

9.16e-043919682.30.29.30
DomainEGF_3

CNTNAP3B CNTNAP3 CNTNAP5 MALRD1 HMCN2 PROC

1.34e-03235966PS50026
DomainGalactose-bd-like

CNTNAP3B CNTNAP3 LAMB2 CNTNAP5

1.40e-0394964IPR008979
Domain-

CLSTN3 CNTNAP3 CNTNAP5 USH2A

1.46e-03959642.60.120.200
DomainVWF_A

CLCA4 CLCA1 HMCN2 ANAPC1

1.70e-0399964IPR002035
DomainAA_permease_2

SLC7A6 SLC7A10

1.97e-0313962PF13520
DomainAA/rel_permease1

SLC7A6 SLC7A10

1.97e-0313962IPR002293
DomainAnkyrin_rpt-contain_dom

AGAP5 ANKRD50 AGAP9 AGAP7P AGAP4 AGAP6

1.99e-03254966IPR020683
DomainANK_REP_REGION

AGAP5 ANKRD50 AGAP9 AGAP7P AGAP4 AGAP6

1.99e-03254966PS50297
DomainSugar/inositol_transpt

SLC2A7 SLC2A5

2.29e-0314962IPR003663
DomainWD40_repeat

FBXW12 LLGL2 WDR6 KCTD3 CORO7 CFAP44

2.80e-03272966IPR001680
DomainLaminin_N

LAMB2 USH2A

2.99e-0316962IPR008211
DomainLAMININ_NTER

LAMB2 USH2A

2.99e-0316962PS51117
DomainLaminin_N

LAMB2 USH2A

2.99e-0316962PF00055
DomainLamNT

LAMB2 USH2A

2.99e-0316962SM00136
DomainWD_REPEATS_1

FBXW12 LLGL2 WDR6 KCTD3 CORO7 CFAP44

3.12e-03278966PS00678
DomainWD_REPEATS_2

FBXW12 LLGL2 WDR6 KCTD3 CORO7 CFAP44

3.18e-03279966PS50082
DomainWD_REPEATS_REGION

FBXW12 LLGL2 WDR6 KCTD3 CORO7 CFAP44

3.18e-03279966PS50294
DomainAminotransferase_I/II

GOT1 GOT2

3.38e-0317962IPR004839
DomainSUGAR_TRANSPORT_2

SLC2A7 SLC2A5

3.38e-0317962PS00217
DomainAminotran_1_2

GOT1 GOT2

3.38e-0317962PF00155
PathwayWP_OXIDATION_BY_CYTOCHROME_P450

CYP4V2 CYP4Z1 CYP4F2 CYP4F3 CYP4F11

1.09e-0562675M39653
PathwayREACTOME_EICOSANOIDS

CYP4F2 CYP4F3 CYP4F11

2.19e-0512673M27129
PathwayREACTOME_MISCELLANEOUS_SUBSTRATES

CYP4F2 CYP4F3 CYP4F11

2.19e-0512673M27128
PathwayREACTOME_EICOSANOIDS

CYP4F2 CYP4F3 CYP4F11

2.19e-0512673MM14845
PathwayREACTOME_ION_CHANNEL_TRANSPORT

CLCA4 SLC9C1 CLCA1 CLCNKB ATP11A ATP1B2 ANO3

2.50e-05183677M997
PathwayWP_EICOSANOID_METABOLISM_VIA_CYTOCHROME_P450_MONOOXYGENASES

CYP4F2 CYP4F3 CYP4F11

3.60e-0514673MM15842
PathwayREACTOME_FATTY_ACIDS

CYP4F2 CYP4F3 CYP4F11

4.48e-0515673M27126
PathwayREACTOME_MISCELLANEOUS_SUBSTRATES

CYP4F2 CYP4F3 CYP4F11

7.96e-0518673MM14843
PathwayREACTOME_FATTY_ACIDS

CYP4F2 CYP4F3 CYP4F11

7.96e-0518673MM14841
PathwayREACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

CYP4F2 CYP4F3 CYP4F11

1.28e-0421673M27137
PathwayREACTOME_STIMULI_SENSING_CHANNELS

CLCA4 SLC9C1 CLCA1 CLCNKB ANO3

1.46e-04106675M27200
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

CLCA4 SLC2A7 SLC7A6 ADCY6 SLC9C1 CLCA1 CLCNKB CIDEC ATP11A ATP1B2 SLC7A10 ANO3

1.59e-047366712M27287
PathwayREACTOME_ION_CHANNEL_TRANSPORT

CLCA4 CLCA1 CLCNKB ATP11A ATP1B2 ANO3

1.85e-04176676MM15718
PathwayREACTOME_BASIGIN_INTERACTIONS

SLC7A6 ATP1B2 SLC7A10

1.93e-0424673MM17215
PathwayREACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

CYP4F2 CYP4F3 CYP4F11

2.19e-0425673MM14858
PathwayREACTOME_BASIGIN_INTERACTIONS

SLC7A6 ATP1B2 SLC7A10

2.19e-0425673M4974
PathwayREACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE

CYP4V2 CYP4F2 CYP4F3 CYP4F11

2.39e-0464674M5650
PathwayREACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE

CYP4V2 CYP4F2 CYP4F3 CYP4F11

2.69e-0466674MM14839
PathwayWP_EICOSANOID_METABOLISM_VIA_CYCLOOXYGENASES_COX

CYP4F2 CYP4F3 CYP4F11

5.06e-0433673MM15918
PathwayWP_EICOSANOID_METABOLISM_VIA_LIPOXYGENASES_LOX

CYP4F2 CYP4F3 CYP4F11

5.06e-0433673MM15963
PathwayREACTOME_MALATE_ASPARTATE_SHUTTLE

GOT1 GOT2

7.84e-049672M48269
PathwayREACTOME_MALATE_ASPARTATE_SHUTTLE

GOT1 GOT2

7.84e-049672MM17242
PathwayREACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL

SLC7A6 PLCG1 ATP1B2 SLC7A10 PROC

9.16e-04158675MM14812
PathwayWP_OXIDATION_BY_CYTOCHROME_P450

CYP4V2 CYP4Z1 CYP4F3

1.11e-0343673MM15873
PathwayREACTOME_SYNTHESIS_OF_16_20_HYDROXYEICOSATETRAENOIC_ACIDS_HETE

CYP4F2 CYP4F11

1.19e-0311672MM14863
PathwayREACTOME_ASPARTATE_AND_ASPARAGINE_METABOLISM

GOT1 GOT2

1.19e-0311672M27836
PathwayREACTOME_STIMULI_SENSING_CHANNELS

CLCA4 CLCA1 CLCNKB ANO3

1.25e-0399674MM14910
PathwayWP_GLYCOLYSIS_AND_GLUCONEOGENESIS

SLC2A5 GOT1 GOT2

1.26e-0345673M39474
PathwayWP_ALANINE_AND_ASPARTATE_METABOLISM

GOT1 GOT2

1.42e-0312672M39331
PathwayREACTOME_ASPARTATE_AND_ASPARAGINE_METABOLISM

GOT1 GOT2

1.42e-0312672MM15556
PathwayREACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS

CYP4V2 CYP4F2 CYP4F3 CYP4F11

1.50e-03104674M738
PathwayREACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS

CYP4V2 CYP4F2 CYP4F3 CYP4F11

1.55e-03105674MM14842
PathwayWP_METAPATHWAY_BIOTRANSFORMATION_PHASE_I_AND_II

CYP4V2 CYP4Z1 CYP4F2 CYP4F3 CYP4F11

1.76e-03183675M39588
PathwayWP_GLYCOLYSIS_AND_GLUCONEOGENESIS

SLC2A5 GOT1 GOT2

1.82e-0351673MM15928
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

NCAPD3 AGAP5 DOLK SMPD4 CHD8 ICE1 ANKRD50 SLC7A6 ARHGEF10L TRIM33 ATG4B MRC2 UNK AGAP9 AGAP7P AGAP4 AGAP6

2.38e-135291011714621295
Pubmed

GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins.

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

2.33e-119101512640130
Pubmed

AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

4.65e-1110101520664521
Pubmed

AGAP1, a novel binding partner of nitric oxide-sensitive guanylyl cyclase.

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

8.51e-1111101515381706
Pubmed

The Endosome Localized Arf-GAP AGAP1 Modulates Dendritic Spine Morphology Downstream of the Neurodevelopmental Disorder Factor Dysbindin.

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

2.36e-1013101527713690
Pubmed

GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity.

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

3.66e-1014101522453919
Pubmed

The cytochrome P450 4 (CYP4) family.

CYP4Z1 CYP4F2 CYP4F3 CYP4F11

1.00e-09610149068972
Pubmed

Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants.

CYP4V2 CYP4Z1 CYP4F2 CYP4Z2P CYP4F3 CYP4F11

5.82e-0870101615128046
Pubmed

Omega oxidation of 3-hydroxy fatty acids by the human CYP4F gene subfamily enzyme CYP4F11.

CYP4F2 CYP4F3 CYP4F11

9.49e-084101318065749
Pubmed

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

AGAP5 DOLK ATG4B UNK AGAP9 AGAP7P AGAP4 AGAP6

2.57e-07218101833378226
Pubmed

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.

DPP6 AGAP5 SPTBN1 NAV3 AGAP9 AGAP7P ATP1B2 AGAP4 AGAP6 GOT1

3.07e-074051011038187761
Pubmed

Highly variable penetrance of abnormal phenotypes in embryonic lethal knockout mice.

SMPD4 HM13 UNK ATP11A

5.65e-0640101427996060
Pubmed

Nucleotide sequence and tissue distribution of the human mitochondrial aspartate aminotransferase mRNA.

GOT1 GOT2

8.35e-06210123207426
Pubmed

Cytochrome P450-dependent catabolism of vitamin K: ω-hydroxylation catalyzed by human CYP4F2 and CYP4F11.

CYP4F2 CYP4F11

8.35e-062101224138531
Pubmed

The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice.

CNTNAP3B CNTNAP3

8.35e-062101231150793
Pubmed

Structural and genetic relationships between cytosolic and mitochondrial isoenzymes.

GOT1 GOT2

8.35e-06210126397370
Pubmed

Effects of therapeutic coronary reperfusion on aspartate aminotransferase isoenzymes in sera of patients with acute myocardial infarction.

GOT1 GOT2

8.35e-06210122731362
Pubmed

Cloning and expression of a novel form of leukotriene B4 omega-hydroxylase from human liver.

CYP4F2 CYP4F3

8.35e-06210128026587
Pubmed

The 3'UTR of the pseudogene CYP4Z2P promotes tumor angiogenesis in breast cancer by acting as a ceRNA for CYP4Z1.

CYP4Z1 CYP4Z2P

8.35e-062101225701119
Pubmed

The competing endogenous RNA network of CYP4Z1 and pseudogene CYP4Z2P exerts an anti-apoptotic function in breast cancer.

CYP4Z1 CYP4Z2P

8.35e-062101228236635
Pubmed

Recurrent PTPRB and PLCG1 mutations in angiosarcoma.

PTPRB PLCG1

8.35e-062101224633157
Pubmed

Caspr3-Deficient Mice Exhibit Low Motor Learning during the Early Phase of the Accelerated Rotarod Task.

CNTNAP3B CNTNAP3

8.35e-062101226807827
Pubmed

Identification of a novel mammary-restricted cytochrome P450, CYP4Z1, with overexpression in breast carcinoma.

CYP4Z1 CYP4Z2P

8.35e-062101215059886
Pubmed

Angiogenesis-related gene mutations drive a subset of angiosarcomas.

PTPRB PLCG1

8.35e-062101224795022
Pubmed

Expression and characterization of human cytochrome P450 4F11: Putative role in the metabolism of therapeutic drugs and eicosanoids.

CYP4F3 CYP4F11

8.35e-062101215364545
Pubmed

New automated measurement of mitochondrial aspartate aminotransferase with use of protease 401.

GOT1 GOT2

8.35e-06210122182221
Pubmed

Cloning and sequence analysis of mRNA for mouse aspartate aminotransferase isoenzymes.

GOT1 GOT2

8.35e-06210123782150
Pubmed

The CLCA gene locus as a modulator of the gastrointestinal basic defect in cystic fibrosis.

CLCA4 CLCA1

8.35e-062101215490240
Pubmed

Chromosomal localization of human aspartate aminotransferase genes by in situ hybridization.

GOT1 GOT2

8.35e-06210122777255
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

AGAP5 FBXW12 SPTBN1 SMPD4 HM13 ELMO1 JARID2 FRRS1 UNK ATP11A AGAP9 AGAP7P AGAP4 AGAP6

1.45e-0512421011430973865
Pubmed

Oncogenic functions of protein kinase D2 and D3 in regulating multiple cancer-related pathways in breast cancer.

AGAP5 GIGYF2 AGAP9 AGAP4 AGAP6

2.32e-05116101530652415
Pubmed

Human CYP4F3s are the main catalysts in the oxidation of fatty acid epoxides.

CYP4F2 CYP4F3

2.50e-053101215145985
Pubmed

Glutamate oxalate transaminase (GOT) genetics in Mus musculus: linkage, polymorphism, and phenotypes of the Got-2 and Got-1 loci.

GOT1 GOT2

2.50e-05310124193185
Pubmed

Expression analysis of the CLCA gene family in mouse and human with emphasis on the nervous system.

CLCA4 CLCA1

2.50e-053101219210762
Pubmed

Differential patterns of inhibition of the sugar transporters GLUT2, GLUT5 and GLUT7 by flavonoids.

SLC2A7 SLC2A5

2.50e-053101229548810
Pubmed

Genetic segregation of airway disease traits despite redundancy of calcium-activated chloride channel family members.

CLCA4 CLCA1

2.50e-053101216569774
Pubmed

Identification of three novel members of the calcium-dependent chloride channel (CaCC) family predominantly expressed in the digestive tract and trachea.

CLCA4 CLCA1

2.50e-053101210437792
Pubmed

Serum aminotransferases in nonalcoholic fatty liver disease are a signature of liver metabolic perturbations at the amino acid and Krebs cycle level.

GOT1 GOT2

2.50e-053101226791191
Pubmed

Genetic analysis of indel markers in three loci associated with Parkinson's disease.

ACE GIGYF2

2.50e-053101228873462
Pubmed

Transcriptional factor six2 promotes the competitive endogenous RNA network between CYP4Z1 and pseudogene CYP4Z2P responsible for maintaining the stemness of breast cancer cells.

CYP4Z1 CYP4Z2P

2.50e-053101230832689
Pubmed

Segmental and restricted localization pattern of Fras1 in the developing meningeal basement membrane in mouse.

FRAS1 LAMB2

4.99e-054101224101214
Pubmed

Adenylyl cyclase 6 plays a minor role in the mouse inner ear and retina.

ADCY6 USH2A

4.99e-054101237127773
Pubmed

Disruption of mouse cytochrome p450 4f14 (Cyp4f14 gene) causes severe perturbations in vitamin E metabolism.

CYP4F2 CYP4F11

4.99e-054101222665481
Pubmed

CLSTN3β enforces adipocyte multilocularity to facilitate lipid utilization.

CLSTN3 CIDEC

4.99e-054101236477540
Pubmed

Expression and catalytic activity of mouse leukotriene B4 omega-hydroxylase, CYP4F14.

CYP4F2 CYP4F11

4.99e-054101211185557
Pubmed

Phospholipid transfer protein activity is determined by type 2 diabetes mellitus and metabolic syndrome, and is positively associated with serum transaminases.

GOT1 GOT2

4.99e-054101217877759
Pubmed

Interactions between pyruvate carboxylase and other mitochondrial enzymes.

GOT1 GOT2

4.99e-05410128349677
Pubmed

Molecular characteristics and functional diversity of CLCA family members.

CLCA4 CLCA1

4.99e-054101211071307
Pubmed

Reassessment of GLUT7 and GLUT9 as Putative Fructose and Glucose Transporters.

SLC2A7 SLC2A5

4.99e-054101228083649
Pubmed

Disruption of P450-mediated vitamin E hydroxylase activities alters vitamin E status in tocopherol supplemented mice and reveals extra-hepatic vitamin E metabolism.

CYP4F2 CYP4F11

8.30e-055101222969154
Pubmed

Cytochrome P4504f, a potential therapeutic target limiting neuroinflammation.

CYP4F2 CYP4F11

8.30e-055101221466787
Pubmed

Cytochromes P450 from family 4 are the main omega hydroxylating enzymes in humans: CYP4F3B is the prominent player in PUFA metabolism.

CYP4F2 CYP4F3

8.30e-055101218577768
Pubmed

Condensin II and GAIT complexes cooperate to restrict LINE-1 retrotransposition in epithelial cells.

EPRS1 NCAPD3

8.30e-055101229028794
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

EPRS1 NCAPD3 FRAS1 CHD8 ANKRD50 ADCY6 LLGL2 WDR6 GIGYF2

1.19e-04650101938777146
Pubmed

A genome-wide association study of self-rated health.

NAV3 PROC

1.24e-046101220707712
Pubmed

Genetic variations associated with diabetic nephropathy and type II diabetes in a Japanese population.

ACE ELMO1

1.24e-046101217653210
Pubmed

In trans neuregulin3-Caspr3 interaction controls DA axonal bassoon cluster development.

CNTNAP3B CNTNAP3

1.24e-046101234143959
Pubmed

An evaluation of nine genetic variants related to metabolism and mechanism of action of warfarin as applied to stable dose prediction.

CYP4F2 PROC

1.24e-046101220499136
Pubmed

Aspartate availability limits hematopoietic stem cell function during hematopoietic regeneration.

GOT1 GOT2

1.74e-047101234450065
Pubmed

Role of ω-hydroxylase in adenosine-mediated aortic response through MAP kinase using A2A-receptor knockout mice.

CYP4F2 CYP4F11

1.74e-047101222160543
Pubmed

Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.

AGAP5 JARID2 SIDT2 ATP11A AGAP9 AGAP7P AGAP4 AGAP6

1.74e-04536101815840001
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

AGAP5 SPTBN1 AGAP9 AGAP7P AGAP4 AGAP6

1.76e-04281101628706196
Pubmed

Exchangeable gene trap using the Cre/mutated lox system.

AGAP5 JARID2 SIDT2 ATP11A AGAP9 AGAP7P AGAP4 AGAP6

1.79e-04538101810512203
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

FRAS1 CLSTN3 ADCY6 ZBED4 NAV3 BRINP2 GIGYF2

1.91e-04407101712693553
Pubmed

Genetic factors (VKORC1, CYP2C9, EPHX1, and CYP4F2) are predictor variables for warfarin response in very elderly, frail inpatients.

CYP4F2 PROC

2.31e-048101219794411
Pubmed

Placentation defects are highly prevalent in embryonic lethal mouse mutants.

SMPD4 HM13 UNK ATP11A

2.38e-04103101429539633
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

CNTNAP3B NCAPD3 DYNC2H1 DOLK CNTNAP3 SMPD4 CHD8 SLC7A6 ADCY6 MALL MRC2

2.63e-0410611011133845483
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

AGAP5 KCTD3 TNK2 AGAP9 AGAP7P AGAP4 AGAP6

2.67e-04430101732581705
Pubmed

Metabolic activation-related CD147-CD98 complex.

SLC7A6 SLC7A10

2.97e-049101215901826
Pubmed

Knockout mice with pituitary malformations help identify human cases of hypopituitarism.

SPTBN1 JARID2 ATP11A

3.09e-0445101338822427
Pubmed

A staging system for correct phenotype interpretation of mouse embryos harvested on embryonic day 14 (E14.5).

SMPD4 JARID2 ATP11A

4.47e-0451101328185240
Pubmed

Guanylate binding protein 1-mediated interaction of T cell antigen receptor signaling with the cytoskeleton.

EPRS1 SPTBN1

4.51e-0411101224337748
Pubmed

The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets.

AGAP5 SPTBN1 KCTD3 AGAP7P AGAP4

5.19e-04225101525277244
Pubmed

De novo genic mutations among a Chinese autism spectrum disorder cohort.

CHD8 GIGYF2

5.41e-0412101227824329
Pubmed

Chd8 Mutation Leads to Autistic-like Behaviors and Impaired Striatal Circuits.

CHD8 CNTNAP5

6.38e-0413101228402856
Pubmed

Genetic determinants of warfarin dosing in the Han-Chinese population.

CYP4F2 PROC

6.38e-0413101219958090
Pubmed

HIV-1 gp120 and chemokines activate ion channels in primary macrophages through CCR5 and CXCR4 stimulation.

CLCA4 CLCA1

7.43e-0414101210758170
Pubmed

Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning.

ADCY6 USH2A

9.76e-0416101217567809
Pubmed

Transcriptional intermediary factor 1γ binds to the anaphase-promoting complex/cyclosome and promotes mitosis.

TRIM33 ANAPC1

1.10e-0317101223160376
Pubmed

Systematic analysis of candidate genes for Alzheimer's disease in a French, genome-wide association study.

ACE SORCS1

1.10e-0317101220413850
Pubmed

Cell adhesion molecule contactin-associated protein 3 is expressed in the mouse basal ganglia during early postnatal stages.

CNTNAP3B CNTNAP3

1.10e-0317101226389685
Pubmed

Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells.

ICE1 JARID2

1.24e-0318101220064376
Pubmed

The ubiquitin E3 ligase ARIH1 regulates hnRNP E1 protein stability, EMT and breast cancer progression.

EPRS1 GIGYF2 CORO7

1.33e-0374101335102251
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

SMPD4 ICE1 HM13 ANAPC1 WDR6 BBS7 UNK CORO7

1.36e-03733101834672954
Pubmed

TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.

CNTNAP3B FRAS1 SPTBN1 LAMB2

1.36e-03164101432409323
Pubmed

A genome-wide assessment of variability in human serum metabolism.

CYP4F2 ACE

1.38e-0319101223281178
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FRAS1 LAMB2 CHD8 ICE1 ARHGEF10L LLGL2 ZBED4 TNK2 PLCG1 FUT1

1.42e-0311051011035748872
Pubmed

Genome-wide association study of ancestry-specific TB risk in the South African Coloured population.

DYNC2H1 NAV3

1.69e-0321101224057671
Pubmed

FoxP1 orchestration of ASD-relevant signaling pathways in the striatum.

CNTNAP3B CNTNAP3

1.86e-0322101226494785
Pubmed

Assessment of Alzheimer's disease case-control associations using family-based methods.

ACE SORCS1

1.86e-0322101218830724
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

NCAPD3 BSPRY LAMB2 ANKRD50 WDR6 KCTD3 PLCG1 CORO7 SNTB2

2.14e-03974101928675297
Pubmed

An atlas of genetic influences on human blood metabolites.

SLC7A6 ACE CYP4Z2P GOT2

2.33e-03190101424816252
Pubmed

Intermediate phenotypes identify divergent pathways to Alzheimer's disease.

ACE SORCS1

2.40e-0325101220574532
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

EPRS1 DYNC2H1 SPTBN1 CHD8 ACE CLEC4F LLGL2 GOT2

2.47e-03807101830575818
Pubmed

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.

DPP6 ELMO1 CNTNAP5 USH2A

2.76e-03199101423382691
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

EPRS1 NCAPD3 DYNC2H1 SPTBN1 JARID2 ANAPC1 WDR6 GIGYF2 PLCG1 GOT2 TMEM117

2.87e-0314251011130948266
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

EPRS1 NCAPD3 SPTBN1 CHD8 ANAPC1

2.89e-03332101532786267
InteractionTRGV3 interactions

CNTNAP3B FRAS1 CLSTN3 CNTNAP3 LAMB2

6.36e-0655965int:TRGV3
InteractionCDHR4 interactions

CNTNAP3B FRAS1 CLSTN3 LAMB2 MRC2

1.82e-0568965int:CDHR4
Cytoband1p36.2

SLC2A7 SLC2A5

3.68e-041310121p36.2
Cytoband1q41

EPRS1 KCTD3 USH2A

4.28e-046610131q41
CytobandEnsembl 112 genes in cytogenetic band chr10q11

AGAP9 AGAP7P AGAP4 AGAP6

8.16e-041881014chr10q11
CytobandEnsembl 112 genes in cytogenetic band chr1q41

EPRS1 KCTD3 USH2A

1.16e-03931013chr1q41
Cytoband3q13.2

SLC9C1 CFAP44

2.14e-033110123q13.2
Cytoband10q11.23

AGAP7P AGAP6

2.42e-0333101210q11.23
Cytoband1p33

CYP4Z1 CYP4Z2P

2.72e-033510121p33
GeneFamilyCytochrome P450 family 4

CYP4V2 CYP4Z1 CYP4F2 CYP4Z2P CYP4F3 CYP4F11

4.40e-09366961003
GeneFamilyArfGAPs

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

1.53e-0733695395
GeneFamilyX-linked mental retardation|Rho GTPase activating proteins|BAR-PH domain containing

AGAP5 AGAP9 AGAP4 AGAP6

4.45e-07176941291
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

AGAP5 SPTBN1 PLCG1 AGAP9 AGAP7P AGAP4 AGAP6

1.34e-05206697682
GeneFamilyChloride channel accessory

CLCA4 CLCA1

8.57e-054692867
GeneFamilyAnkyrin repeat domain containing

AGAP5 ANKRD50 AGAP9 AGAP7P AGAP4 AGAP6

3.20e-04242696403
GeneFamilyWD repeat domain containing

FBXW12 LLGL2 WDR6 CORO7 CFAP44

3.25e-03262695362
CoexpressionTHEODOROU_MAMMARY_TUMORIGENESIS

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

2.61e-0737985MM1121
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_F_DN

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

6.38e-0744985MM485
CoexpressionBUSSLINGER_DUODENAL_MATURE_ENTEROCYTES

CYP4F2 ACE SLC2A5 ATG4B MALL CIDEC TM4SF20 DGAT1

5.96e-06259988M40029
CoexpressionAtlassmall intestine

SLC2A7 CYP4F2 ACE SLC2A5 MALRD1 CLCA1 CYP4F11 TM4SF20 DGAT1

2.13e-05339959small intestine
ToppCell5'-Adult-SmallIntestine-Epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CYP4F2 ACE SLC2A5 MALRD1 MALL CIDEC TM4SF20 DGAT1

1.74e-0819810188d629492d2199de8e036c19e9dacceb9c9e721a0
ToppCell5'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CYP4F2 ACE SLC2A5 MALRD1 MALL CIDEC TM4SF20 DGAT1

1.74e-0819810186e6af8fad09f8e48b3f2ce463d5773b6a69864d1
ToppCell5'-Adult-SmallIntestine-Epithelial-mature_enterocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CYP4F2 ACE SLC2A5 MALRD1 MALL CIDEC TM4SF20 DGAT1

1.81e-08199101801c2721bc82cd672e9477029b4a7ecc77e2f1b00
ToppCellEnterocyte|World / shred on cell type and cluster

CYP4F2 ACE SLC2A5 MALL CIDEC TM4SF20 DGAT1

3.37e-0719710171dd980fd066aef21694395a4b69df938501d9631
ToppCellC_01|World / shred on cell type and cluster

CYP4F2 ACE SLC2A5 MALL CIDEC TM4SF20 DGAT1

3.49e-07198101771d38084d09a96331877384ce6346f0de4bdcef9
ToppCellEnterocyte-C_01|Enterocyte / shred on cell type and cluster

CYP4F2 ACE SLC2A5 MALL CIDEC TM4SF20 DGAT1

3.49e-0719810174e2c30d6fd1d59db98a52bfcc3206b4c4ac5abe2
ToppCell5'-Adult-SmallIntestine|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CYP4F2 ACE SLC2A5 MALRD1 CIDEC TM4SF20 DGAT1

3.61e-071991017a5fffe381be1ba7d192b68d1d3937ce47663658e
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CNTNAP3B CNTNAP3 CYP4F2 PTPRB CYP4F3 FUT1

8.80e-071421016191a13bba143ecdfc2bfd797c3ac191481388298
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CNTNAP3B CNTNAP3 CYP4F2 PTPRB CYP4F3 FUT1

9.17e-071431016b405dba9a83a99cc7b53ce71772bc52a0bbb0d4e
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 PKD1L2 SORCS1 NAV3 USH2A ANO3

3.96e-0618410162cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 PKD1L2 SORCS1 NAV3 USH2A ANO3

3.96e-061841016ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 PKD1L2 SORCS1 NAV3 USH2A ANO3

3.96e-0618410162b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell3'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CYP4F2 ACE MALRD1 CIDEC TM4SF20 DGAT1

4.34e-0618710169042bd0f57213a51503d9df2e4dce3209b7772d3
ToppCellTracheal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CNTNAP3B CNTNAP3 ACE PTPRB MALL PLCG1

6.21e-061991016bd43a84e84d8acb8e1008b98a235cc5bd5f43586
ToppCellfacs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPP6 FRAS1 SORCS1 BRINP2 PROC

1.75e-0514110154aa4b3476dc5abefbd348353cfe711cd5fe3d52f
ToppCellfacs-Heart-Unknown-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPP6 FRAS1 SORCS1 BRINP2 PROC

1.75e-051411015e40c6f1b7fbaa46b3eaa55f1b37ef360b04370a8
ToppCellkidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CYP4V2 CYP4F2 ADCY6 SLC2A5 MALL

2.00e-05145101547a3bb973a508d3097213a2d86ad1ce697af9bae
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Mesenchymal|GW19 / Sample Type, Dataset, Time_group, and Cell type.

CHD8 SHQ1 JARID2 PTPRB CIDEC

3.12e-051591015f34f2729a3872fbb2939e76ad35d7e25f71b8f57
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Mesenchymal-Unfolded_protein_responsible_cell|GW19 / Sample Type, Dataset, Time_group, and Cell type.

CHD8 SHQ1 JARID2 PTPRB CIDEC

3.12e-051591015929ed98f6c2ad14e8d5af5c6f11a5a3d4b388cf7
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE SLC2A5 ATP11A USH2A PROC

3.94e-051671015ed7e785dcd25777f64e0c2596ada4f5a5ea17121
ToppCell3'-Adult-LargeIntestine-Epithelial-goblet-Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DPP6 CYP4F2 CLCA1 ATP1B2 PROC

4.06e-0516810152163e6774eb7a3d010422e4d59be5e45b4158329
ToppCelldroplet-Kidney-nan-18m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE SLC2A5 ATP11A USH2A PROC

4.17e-051691015f00741203efa0b948db7223ee8c19bdd0918258a
ToppCellfacs-Brain_Myeloid-Cortex-24m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCA4 BSPRY SLC2A5 CLEC4F TMEM117

5.48e-0517910150cef6d2eab2015cac0dd340532b24bfec9707330
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CNTNAP3B SPTBN1 ELMO1 PTPRB NAV3

5.48e-0517910158f9e538c822940785130297712b75131812a4603
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMB2 ACE ADCY6 PTPRB MALL

5.93e-051821015c7f2d24697affa530b748ab32b1d40bdc1bdc20a
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMB2 ACE ADCY6 PTPRB MALL

5.93e-051821015d95635b74e8cd8bc00bfe40340806b59fb9bee43
ToppCellIPF-Epithelial-ATI|World / Disease state, Lineage and Cell class

CYP4Z1 LAMB2 CYP4Z2P SLC9C1 MALL

6.09e-05183101531fef35ecf30162662f24d335d8f0cceacc07039
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CNTNAP3B SPTBN1 CNTNAP3 LAMB2 NAV3

6.09e-0518310154d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DPP6 FRAS1 LLGL2 MALL ATP11A

6.25e-05184101542ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCell3'-Adult-SmallIntestine-Epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ACE MALRD1 CIDEC TM4SF20 DGAT1

6.25e-051841015ed7a8e79e5723a5f5a03f542203d9e50bdef5f50
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DPP6 FRAS1 LLGL2 MALL ATP11A

6.41e-051851015c82eab551f65ecebe6db908eda9f9eb3414693c7
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

FRAS1 ADCY6 JARID2 LLGL2 TMEM117

6.57e-051861015de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCell3'-Adult-SmallIntestine-Epithelial-mature_enterocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ACE MALRD1 CIDEC TM4SF20 DGAT1

6.57e-051861015bdd9d3a432aab46e733469b362f0064d35c1ac49
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DPP6 FRAS1 LLGL2 MALL ATP11A

6.57e-0518610154e94158db52df41d71e67b02b9895a358eebee0f
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DPP6 FRAS1 LLGL2 MALL ATP11A

6.57e-0518610153aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

DPP6 FRAS1 SORCS1 CNTNAP5 NAV3

6.57e-0518610158915436d09775f2828a7678af203b1082b36e21c
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

FRAS1 ADCY6 JARID2 LLGL2 TMEM117

6.57e-0518610150b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

DPP6 FRAS1 ELMO1 NAV3 ANO3

6.74e-05187101592d468dde81125d51daf7abd4703741abe1ab91c
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DPP6 FRAS1 LLGL2 MALL ATP11A

6.74e-05187101558d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CNTNAP3B SPTBN1 ACE PTPRB NAV3

6.91e-051881015117dc80fa940e6aa1b0187a43fdde33f3fcb578f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CNTNAP3B CNTNAP3 ELMO1 PTPRB HMCN2

7.09e-0518910156463890d8dbee4bc198f91628a5f784970de786a
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

DPP6 FRAS1 CNTNAP3 CNTNAP5 NAV3

7.45e-051911015156b467187331ac6ca390d6ca861d9670bb7b956
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

SLC9C1 LLGL2 MALRD1 MALL ATP11A

7.45e-051911015d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCellCOVID-19-Heart-EC_(POSTN)|Heart / Disease (COVID-19 only), tissue and cell type

CNTNAP3B CNTNAP3 ANKRD50 ELMO1 PTPRB

7.64e-051921015c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCellhuman_hepatoblastoma-Tumor_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

FRAS1 ARHGEF10L FRRS1 LLGL2 TMEM117

7.82e-051931015503a979328c68b096680b71359a26f02fafdff35
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)|Children_(3_yrs) / Lineage, Cell type, age group and donor

CNTNAP3B SPTBN1 PTPRB NAV3 FUT1

8.02e-05194101571ac69cdf7a08ca3ddfb5b492b14ac56b6cd5e5d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CNTNAP3B SPTBN1 ELMO1 PTPRB NAV3

8.02e-05194101574a9fdb73f279bebb6337510deab9aaaf9f7e957
ToppCell3'-Child09-12|3' / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CYP4F2 ACE CIDEC TM4SF20 DGAT1

8.41e-0519610151bcc4ffff51cdb6211824686c2422c43b09e24b2
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CNTNAP3B SPTBN1 ELMO1 PTPRB NAV3

8.41e-05196101522767bcf0095d9eb0cbed7cdc74e4d32d9357e1b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CNTNAP3B SPTBN1 ELMO1 PTPRB NAV3

8.41e-051961015adee900dcd16dbaba15c58bdcace09ba20214950
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ACE MALL CIDEC TM4SF20 DGAT1

8.83e-051981015c48b3f026b16d48b8eca9f74dc1e3f3f39a89322
ToppCellControl-Control-Lymphocyte-T/NK-CD4+_T_activated|Control / Disease, condition lineage and cell class

SPTBN1 CNTNAP3 PTPRB MRC2 PLCG1

8.83e-051981015ee71543559836fd59adc0da877b2ca538cba60cb
ToppCellControl_saline|World / Treatment groups by lineage, cell group, cell type

FRAS1 SPTBN1 LAMB2 ANKRD50 ACE

9.04e-05199101511c9c1779caceb725ecccf3f23b7d4e6dbd1af64
ToppCellsevere-NK_CD56bright|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

DPP6 FRAS1 CLSTN3 CLDND1 ZBED4

9.25e-05200101582818ab1796fdd0b8be02b341818897595eed841
ToppCellsevere-NK_CD56bright|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

DPP6 FRAS1 CLSTN3 CLDND1 ZBED4

9.25e-0520010152e67068b98696c313b815a2f0c98643f892e8bc0
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DPP6 EXTL1 CNTNAP5 TNK2 SLC7A10

9.25e-052001015ad777683adeb2ce45ade570386235e311fa7ea2d
Drughydrazinosuccinate

GOT1 GOT2

1.83e-052982CID000124897
Drugbeta-Ethylideneaspartate

GOT1 GOT2

1.83e-052982CID006444096
Drugnitrosomethoxymethylamine

GOT1 GOT2

1.83e-052982CID000027827
DrugBAPM

GOT1 GOT2

1.83e-052982CID000191773
Drugperfluorosuccinate

GOT1 GOT2

1.83e-052982CID000067833
Drugcystinedisulfoxide

GOT1 GOT2

1.83e-052982CID000121714
Drugthreo-alpha-cycloglutamic acid

GOT1 GOT2

1.83e-052982CID000193353
Drug6-fluoropyridoxamine 5'-phosphate

GOT1 GOT2

1.83e-052982CID006451848
DrugTa 4

GOT1 GOT2

1.83e-052982CID000203778
DrugPD 123244-15

GOT1 GOT2

1.83e-052982CID000132851
Drugpyridoxal 5'-sulfate

GOT1 GOT2

1.83e-052982CID000162410
DrugAzathioprine [446-86-6]; Up 200; 14.4uM; MCF7; HT_HG-U133A

ADCY6 SLC2A5 GHRHR SIDT2 CLCA1 BRINP2 CYP4F11

2.32e-051979875262_UP
Drugtienilic acid

CYP4Z1 CYP4F2 ADCY6 CYP4F3 CYP4F11

5.13e-0593985CID000038409
Drugpyridoxamine-5-thiophosphate

GOT1 GOT2

5.49e-053982CID000198275
Drug5-hydroxyindolepyruvate

GOT1 GOT2

5.49e-053982CID000440742
Druggossypitrin

GOT1 GOT2

5.49e-053982CID006452123
Drugbromobenzene

CYP4Z1 GHRHR CYP4F11 GOT1 GOT2

6.28e-0597985CID000007961
Diseasecerebral palsy (implicated_via_orthology)

AGAP5 AGAP9 AGAP7P AGAP4 AGAP6

8.60e-1110975DOID:1969 (implicated_via_orthology)
Diseaseautosomal recessive intellectual developmental disorder (implicated_via_orthology)

CNTNAP3B CNTNAP3 CNTNAP5

1.91e-068973DOID:0060308 (implicated_via_orthology)
Diseasehexadecanedioate measurement

CYP4F2 CYP4Z2P

1.06e-045972EFO_0021055
Diseaseproteinuria (implicated_via_orthology)

LAMB2 ACE SORCS1

1.31e-0430973DOID:576 (implicated_via_orthology)
Diseaseneuritic plaque measurement

DPP6 DYNC2H1 CYP4F2 ICE1 CLCA1 CYP4F11 GOT2

1.57e-04349977EFO_0006798
DiseaseAutism Spectrum Disorders

DPP6 CHD8 JARID2 USH2A

1.81e-0485974C1510586
Disease10-undecenoate 11:1n1 measurement

CYP4Z1 CYP4Z2P

2.22e-047972EFO_0021099
Diseaseoctadecanedioylcarnitine (C18-DC) measurement

CYP4V2 CYP4F2

2.22e-047972EFO_0800371
Diseasenephrosis (implicated_via_orthology)

LAMB2 ACE

2.22e-047972DOID:2527 (implicated_via_orthology)
Diseasehoarding disorder

CNTNAP5 MRC2 SLC7A10

2.27e-0436973EFO_0803361
Diseaseresponse to darapladib, cardiovascular event measurement

ANKRD50 ANO3

2.96e-048972EFO_0006919, EFO_0008395
Diseasehexadecenedioate (C16:1-DC) measurement

CYP4F2 CYP4F11

3.79e-049972EFO_0800562
Diseasemetabolite measurement

CYP4F2 ICE1 PKD1L2 SLC7A6 ACE SORCS1 CYP4Z2P GOT2

5.27e-04560978EFO_0004725
Diseasecongenital left-sided heart lesions

FRAS1 PKD1L2 GHRHR

5.35e-0448973EFO_0005938
Diseasetoxic shock syndrome (is_implicated_in)

ACE PROC

8.15e-0413972DOID:14115 (is_implicated_in)
Diseasebasophil count, eosinophil count

ELMO1 SLC9C1 ANAPC1 UNK SLC7A10

1.22e-03241975EFO_0004842, EFO_0005090
Diseaseprotein C measurement

ELMO1 PROC

1.41e-0317972EFO_0004633
DiseaseHemangiosarcoma

PTPRB PLCG1

1.58e-0318972C0018923
Diseaseautism spectrum disorder (implicated_via_orthology)

CNTNAP3B CNTNAP3 CHD8 CNTNAP5

1.62e-03152974DOID:0060041 (implicated_via_orthology)
Diseasenucleotide measurement

DPP6 DOLK PTPRB

1.81e-0373973EFO_0010513
Diseasepre-eclampsia (is_implicated_in)

ACE PROC

3.05e-0325972DOID:10591 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
NNFMIVSATGQTWHF

AGAP4

386

Q96P64
FMFAGHDTTTTAISW

CYP4Z2P

311

Q8N1L4
LTGQFSFAEVHSWVV

BBS7

511

Q8IWZ6
VWMAFSSGTSIRLFH

ARHGEF10L

1026

Q9HCE6
WTEMNTIVYHGSLAS

CHD8

881

Q9HCK8
VSFSAKWSHMNVVVD

CNTNAP3

456

Q9BZ76
MDHGIVSWDTFSVAF

ELMO1

166

Q92556
FMIVSATGQTWHFEA

AGAP9

456

Q5VTM2
SDHFTLSFWMKHGVT

CLSTN3

371

Q9BQT9
GWNATHMFRVAEEFF

ACE

316

P12821
NAFAFWMTPSVGHLA

SLC7A10

221

Q9NS82
HSFRQDSMWVVSYVV

ADCY6

201

O43306
MGHASVVNTLLFWGA

ANKRD50

791

Q9ULJ7
WMARTGVFLASAFFH

DGAT1

401

O75907
SGSGHIKFWEMAFTF

CFAP44

291

Q96MT7
AVFDTWSSLAVHIAM

ATG4B

156

Q9Y4P1
TFSHASDTWMFGVTL

TNK2

306

Q07912
NNFMIVSATGQTWHF

AGAP6

386

Q5VW22
GTVFFAIFMAIWATV

ANO3

471

Q9BYT9
VMTYDAVQNVHSVWT

ANAPC1

256

Q9H1A4
SASWMGGFVHSIVQI

OR4D11

146

Q8NGI4
HVANQGMTSSLFTNW

PTPRB

561

P23467
GWASLEHHTEMEFSF

FRAS1

3486

Q86XX4
FIMGNHARESAVWAF

MAGEE1

846

Q9HCI5
VFMDSGTWASSIFFH

DOLK

246

Q9UPQ8
AAGSRQNAHFSTMEW

LLGL2

406

Q6P1M3
IFGFLVWTMVAATHI

MALL

36

Q13021
SLTQMEFAAHTWTGQ

FAM149A

731

A5PLN7
IQFCGHSWIFTNMTV

HACD4

26

Q5VWC8
AAFMVDGAVHWLTNF

SLC2A7

416

Q6PXP3
ATLAFVFDVTGSMWD

HMCN2

36

Q8NDA2
THQFMGRTGTSWAFI

ATP1B2

26

P14415
MGTWEHLVSTGFNQM

CORO7

221

P57737
GTMIWSSPVQEFHFS

FBXW12

136

Q6X9E4
MGFSNSWDIQIVHAA

OR14L1P

16

Q8NHC6
FQMWLIHSFQAIESG

OR52A5

101

Q9H2C5
VAASWMGGFVHSTVQ

OR4Q2

146

P0C623
VHSFTSGGLVWAANM

NAV3

1336

Q8IVL0
MNFEWSDGSLVSFTH

MRC2

451

Q9UBG0
TGVLGAFESSFWHMQ

LAMB2

1221

P55268
FWVFGTNVMVTVAKS

HM13

221

Q8TCT9
HSFLSWLGFSSMDTN

SMPD4

621

Q9NXE4
FFMKTSAGFQDGHIW

PKD1L2

1521

Q7Z442
WSFSVAEEMQSGSFV

PCDHB11

31

Q9Y5F2
MVASFHGTWFLVGLV

PROC

406

P04070
TLVFWTHMNGATVGS

MALRD1

1176

Q5VYJ5
TVEAQGFQASDMHAW

DYNC2H1

731

Q8NCM8
FIANMWHDIFLSQSV

ICE1

2031

Q9Y2F5
LAATSFQNGLHAWMV

BSPRY

276

Q5W0U4
VWGMNHSTLHSVFQT

GIGYF2

1231

Q6Y7W6
AMTGFVAWHVGTEVV

FRRS1

516

Q6ZNA5
MFEGHDTTASGLSWV

CYP4F11

326

Q9HBI6
WNHITDQIGMFSFTG

GOT1

351

P17174
NNFMIVSATGQTWHF

AGAP7P

386

Q5VUJ5
FMFEGHDTTAAAINW

CYP4V2

326

Q6ZWL3
MFEGHDTTASGLSWV

CYP4F2

326

P78329
VAASHFATMTNFSWL

GHRHR

206

Q02643
FEEHFVASSVGEMWQ

LLCFC1

51

Q96L11
MFEGHDTTASGLSWV

CYP4F3

326

Q08477
FEVSWETVMVSSHGA

DPP6

641

P42658
FTGHTNGSIQMWDLT

KCTD3

556

Q9Y597
IWTFAGNMNADSVVH

CNTNAP5

126

Q8WYK1
VSFSAKWSHMNVVVD

CNTNAP3B

456

Q96NU0
FTFSGSAMHWVRQAS

IGHV3-73

46

A0A0B4J1V6
SETVHFATTQWTSMG

JARID2

1026

Q92833
KSGHEIWEEFSMSFT

NR1D2

396

Q14995
NHTIMTIGTFGFWAA

FUT1

301

P19526
FGSAHSSWIPFMTAE

USH2A

2516

O75445
ESSGVDTMTHNNFWL

SNX4

41

O95219
HVMNFTNWAIASGSS

TRIM33

411

Q9UPN9
EFLWQEGHSAFATME

EPRS1

1166

P07814
HDIWHFLSSIAMFGS

SIDT2

796

Q8NBJ9
QFWMSTVFGDDVNHI

SLC9C1

231

Q4G0N8
AFMVGGSVHWLSNFT

SLC2A5

411

P22732
FETWTNVHDIMVSFG

SHQ1

311

Q6PI26
MVGFLTSSHFWDEAH

EXTL1

521

Q92935
FMHSVGRVFSKWGES

OSM

201

P13725
HNFTTSWRDGMAFNA

SPTBN1

196

Q01082
MASGWRASSFHFDSE

TM4SF20

166

Q53R12
SHSESWFMPVNEGSF

BRINP2

596

Q9C0B6
WQHITDQIGMFCFTG

GOT2

371

P00505
FMIVSATGQTWHFEA

AGAP5

411

A6NIR3
QFMASALFIWAAHTN

CLDND1

226

Q9NY35
EAFRWALFSMQATGH

CIDEC

186

Q96AQ7
TFKGHMENSSAWVVE

CLEC4F

106

Q8N1N0
GSWVGMVTFDSAAHV

CLCA1

341

A8K7I4
TGEHGSMESIWTFFI

NCAPD3

66

P42695
GSWVGMVHFDSTATI

CLCA4

341

Q14CN2
LFSIEVMSSHFSVWD

CLCNKB

221

P51801
NWTFGTLVFTVMVFT

ATP11A

1001

P98196
FMFAGHDTTSSAISW

CYP4Z1

311

Q86W10
FSSTQSHMDWGKVAF

UBTFL6

41

P0CB48
VFSISMASVAHWSLD

PLCG1

896

P19174
SMVILGFHANEFVVW

WDR6

626

Q9NNW5
TFIFTSDHGMTDWGS

PIGN

256

O95427
VTFADQTFGMFSWTI

SLC7A6

306

Q92536
HASALMAALAGVFVW

STARD7

71

Q9NQZ5
FREDHGSWMTMFFST

TMEM117

101

Q9H0C3
MTVFGHFSHRSEWQL

SORCS1

646

Q8WY21
ATAHSWFVAIHTNIM

SNTB2

286

Q13425
GMNSSIWEHFASGSF

UNK

616

Q9C0B0
GVIHFTSGIWMSNQT

ZBED4

726

O75132