Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix structural constituent conferring tensile strength

COL4A2 COL4A4 COL6A6 COL27A1 COL6A5

5.57e-05461795GO:0030020
GeneOntologyMolecularFunctionenoyl-[acyl-carrier-protein] reductase activity (NAD(P)H)

FASN MECR

7.99e-0521792GO:0016631
GeneOntologyMolecularFunctionenoyl-[acyl-carrier-protein] reductase (NADPH) activity

FASN MECR

7.99e-0521792GO:0141148
GeneOntologyMolecularFunctionNADH oxidase H202-forming activity

DUOX2 DUOX1

7.99e-0521792GO:0106293
GeneOntologyMolecularFunctionbenzodiazepine receptor activity

TSPO GABRA4 GABRA6

1.11e-04111793GO:0008503
GeneOntologyMolecularFunctionextracellular matrix structural constituent

COL4A2 COL4A4 COL6A6 COL27A1 EMID1 COL6A5 ELN MUC4

3.02e-041881798GO:0005201
GeneOntologyMolecularFunctionGABA-A receptor activity

GABRD GABRA4 GABRA6

6.18e-04191793GO:0004890
GeneOntologyMolecularFunctiontRNA (uridine) methyltransferase activity

TRMT2B TRMT44

7.85e-0451792GO:0016300
GeneOntologyMolecularFunctionNADPH oxidase H202-forming activity

DUOX2 DUOX1

7.85e-0451792GO:0106294
GeneOntologyCellularComponentcollagen trimer

COL4A2 COL4A4 COL6A6 COL27A1 EMID1 COL6A5

1.10e-04881796GO:0005581
GeneOntologyCellularComponentUSH2 complex

PDZD7 USH2A

4.33e-0441792GO:1990696
GeneOntologyCellularComponentGABA-A receptor complex

GABRD GABRA4 GABRA6

5.41e-04191793GO:1902711
GeneOntologyCellularComponentextracellular matrix

COL4A2 COL4A4 ADAMTS4 LRRC24 COL6A6 COL27A1 EMID1 MMP27 COL6A5 ANGPTL1 ELN MMP14 USH2A MUC4 ALPL

5.42e-0465617915GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

COL4A2 COL4A4 ADAMTS4 LRRC24 COL6A6 COL27A1 EMID1 MMP27 COL6A5 ANGPTL1 ELN MMP14 USH2A MUC4 ALPL

5.59e-0465817915GO:0030312
GeneOntologyCellularComponentGABA receptor complex

GABRD GABRA4 GABRA6

7.33e-04211793GO:1902710
GeneOntologyCellularComponentcomplex of collagen trimers

COL4A2 COL4A4 COL27A1

7.33e-04211793GO:0098644
GeneOntologyCellularComponentstereocilia ankle link

PDZD7 USH2A

1.07e-0361792GO:0002141
GeneOntologyCellularComponentstereocilia ankle link complex

PDZD7 USH2A

1.07e-0361792GO:0002142
GeneOntologyCellularComponentcollagen type IV trimer

COL4A2 COL4A4

1.07e-0361792GO:0005587
GeneOntologyCellularComponentpericiliary membrane compartment

KIFAP3 USH2A

1.07e-0361792GO:1990075
GeneOntologyCellularComponentglycogen granule

PPP1CA FASN

1.97e-0381792GO:0042587
GeneOntologyCellularComponentstereocilia coupling link

PDZD7 USH2A

1.97e-0381792GO:0002139
GeneOntologyCellularComponentbasement membrane collagen trimer

COL4A2 COL4A4

1.97e-0381792GO:0098651
GeneOntologyCellularComponentnetwork-forming collagen trimer

COL4A2 COL4A4

1.97e-0381792GO:0098642
GeneOntologyCellularComponentcollagen network

COL4A2 COL4A4

1.97e-0381792GO:0098645
DomainDUOX1

DUOX2 DUOX1

8.93e-0521772IPR029595
DomainCollagen

COL4A2 COL4A4 COL6A6 COL27A1 EMID1 COL6A5

1.57e-04851776IPR008160
DomainCollagen

COL4A2 COL4A4 COL6A6 COL27A1 EMID1 COL6A5

1.57e-04851776PF01391
DomainEGF_LAM_2

STAB2 CELSR1 MEGF8 USH2A

1.76e-04301774PS50027
DomainEGF_LAM_1

STAB2 CELSR1 MEGF8 USH2A

1.76e-04301774PS01248
DomainConA-like_dom

PTX4 TMPRSS15 COL27A1 MAMDC4 CELSR1 NRXN2 SEL1L3 MDGA1 USH2A

2.48e-042191779IPR013320
DomainEGF_Lam

STAB2 CELSR1 MEGF8 USH2A

3.25e-04351774SM00180
DomainMAM_1

TMPRSS15 MAMDC4 MDGA1

4.28e-04161773PS00740
DomainLAM_G_DOMAIN

COL27A1 CELSR1 NRXN2 USH2A

4.47e-04381774PS50025
DomainLaminin_EGF

STAB2 CELSR1 MEGF8 USH2A

4.47e-04381774IPR002049
DomainAAA

VPS4A ABCA7 ABCA9 DMC1 DNAH12 AFG3L2 NAV3

4.51e-041441777SM00382
DomainAAA+_ATPase

VPS4A ABCA7 ABCA9 DMC1 DNAH12 AFG3L2 NAV3

4.51e-041441777IPR003593
DomainMAM

TMPRSS15 MAMDC4 MDGA1

5.16e-04171773SM00137
DomainSUZ

R3HDM2 R3HDM1

5.29e-0441772IPR024771
DomainAlk_phosphatase

ALPL ALPP

5.29e-0441772PF00245
DomainAlkaline_phosphatase_AS

ALPL ALPP

5.29e-0441772IPR018299
DomainSUZ

R3HDM2 R3HDM1

5.29e-0441772PS51673
DomainAlkaline_phosphatase

ALPL ALPP

5.29e-0441772IPR001952
DomainalkPPc

ALPL ALPP

5.29e-0441772SM00098
DomainALKALINE_PHOSPHATASE

ALPL ALPP

5.29e-0441772PS00123
DomainMAM

TMPRSS15 MAMDC4 MDGA1

6.15e-04181773PF00629
DomainMAM_dom

TMPRSS15 MAMDC4 MDGA1

6.15e-04181773IPR000998
DomainMAM_2

TMPRSS15 MAMDC4 MDGA1

6.15e-04181773PS50060
DomainCUB

TMPRSS15 CSMD2 CSMD3 MEGF8

1.18e-03491774PF00431
DomainCUB

TMPRSS15 CSMD2 CSMD3 MEGF8

1.28e-03501774SM00042
DomainGABAA/Glycine_rcpt

GABRD GABRA4 GABRA6

1.29e-03231773IPR006028
DomainC4

COL4A2 COL4A4

1.31e-0361772SM00111
DomainCollagen_VI_NC

COL4A2 COL4A4

1.31e-0361772IPR001442
DomainNC1_IV

COL4A2 COL4A4

1.31e-0361772PS51403
Domain-

COL4A2 COL4A4

1.31e-03617722.170.240.10
DomainC4

COL4A2 COL4A4

1.31e-0361772PF01413
DomainGABAAa_rcpt

GABRA4 GABRA6

1.31e-0361772IPR001390
PathwayREACTOME_NCAM1_INTERACTIONS

COL4A2 COL4A4 COL6A6 COL6A5

2.81e-05201284MM15061
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL4A2 COL4A4 COL6A6 COL27A1 COL6A5

4.67e-05441285M27812
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

COL4A2 COL4A4 COL6A6 COL6A5 ITGA2B ITGAL

6.48e-05761286MM14867
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

COL4A2 COL4A4 ADAMTS4 COL6A6 COL6A5 ELN MMP14

7.94e-051141287MM14571
PathwayBIOCARTA_NPP1_PATHWAY

COL4A2 COL4A4 ALPL

8.38e-05101283M22040
PathwayBIOCARTA_NPP1_PATHWAY

COL4A2 COL4A4 ALPL

8.38e-05101283MM1560
PathwayREACTOME_COLLAGEN_DEGRADATION

COL4A2 COL4A4 COL6A6 COL6A5 MMP14

1.16e-04531285MM14566
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

COL4A2 COL4A4 COL6A6 COL6A5 ITGA2B ITGAL

1.21e-04851286M16441
PathwayWP_GABA_RECEPTOR_SIGNALING

GABRD SLC6A1 GABRA4 GABRA6

1.69e-04311284M39369
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

COL4A2 COL4A4 COL6A6 COL27A1 COL6A5

2.26e-04611285M27103
PathwayREACTOME_COLLAGEN_DEGRADATION

COL4A2 COL4A4 COL6A6 COL6A5 MMP14

2.83e-04641285M26953
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

COL4A2 COL4A4 ADAMTS4 COL6A6 COL6A5 ELN MMP14

2.85e-041401287M587
PathwayREACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES

COL4A2 COL4A4 COL6A6 COL27A1 COL6A5

3.51e-04671285M26999
PathwayREACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH

COL4A2 COL4A4 COL6A6 COL6A5

3.77e-04381284MM14969
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

COL4A2 COL4A4 ADAMTS4 COL6A6 COL27A1 COL6A5 ITGA2B ITGAL ELN MMP14

4.07e-0430012810M610
PathwayKEGG_FOCAL_ADHESION

COL4A2 COL4A4 FLNB FLNC COL6A6 ITGA2B PPP1CA CTNNB1

4.61e-041991288M7253
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL4A2 COL4A4 COL6A6 COL6A5

5.06e-04411284MM15538
PathwayREACTOME_NCAM1_INTERACTIONS

COL4A2 COL4A4 COL6A6 COL6A5

5.56e-04421284M7169
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

COL4A2 COL4A4 ADAMTS4 COL6A6 COL6A5 ITGA2B ITGAL ELN MMP14

5.75e-042581289MM14572
PathwayREACTOME_ECM_PROTEOGLYCANS

COL4A2 COL4A4 COL6A6 COL6A5 ITGA2B

6.30e-04761285M27219
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MON2 DGCR2 SEMA4F FLNC RHBDF1 LRRC24 PCNX3 EMID1 FBRS CEP192 PRAG1 ABCA7 CCDC142 FASN CELSR1 AATK PNPLA6 MEGF8 SLC45A3 ZNRF1 MMP14 RAI1

8.21e-0811051812235748872
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MON2 MBTPS1 ZNF536 R3HDM2 CEP192 CSMD3 USP19 MEGF8 SEL1L3 NAV3 CHPF2 R3HDM1

1.69e-064071811212693553
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

FLNB RBM45 MAGI3 OAZ1 SHANK3 SRRT RPIA MEGF8 DACH2 CHRD CTNNB1 R3HDM1 PCCB

8.41e-065601811321653829
Pubmed

Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.

COL4A2 VPS4A ITGA2B CPS1 GGCX SEMA4C FASN MEGF8 AFG3L2 SEL1L3 CHPF2 ALPL ALPP

2.17e-056131811322268729
Pubmed

FASN-dependent de novo lipogenesis is required for brain development.

FASN CTNNB1 EMX1

2.22e-0511181334996870
Pubmed

USP19 deubiquitinating enzyme supports cell proliferation by stabilizing KPC1, a ubiquitin ligase for p27Kip1.

FLNB FLNC USP19

2.22e-0511181319015242
Pubmed

Digenic DUOX1 and DUOX2 Mutations in Cases With Congenital Hypothyroidism.

DUOX2 DUOX1

2.69e-052181228633507
Pubmed

A critical role for alpha4betadelta GABAA receptors in shaping learning deficits at puberty in mice.

GABRD GABRA4

2.69e-052181220299596
Pubmed

Vps4A mediates the localization and exosome release of β-catenin to inhibit epithelial-mesenchymal transition in hepatocellular carcinoma.

VPS4A CTNNB1

2.69e-052181231059752
Pubmed

Translocator protein (18 kDa) regulates the microglial phenotype in Parkinson's disease through P47.

NSFL1C TSPO

2.69e-052181235475466
Pubmed

Planar cell polarity cadherin Celsr1 regulates skin hair patterning in the mouse.

CELSR1 EMX1

2.69e-052181219357712
Pubmed

Reactive oxygen species regulate the levels of dual oxidase (Duox1-2) in human neuroblastoma cells.

DUOX2 DUOX1

2.69e-052181222523549
Pubmed

Expression of dual oxidases and secreted cytokines in chronic rhinosinusitis.

DUOX2 DUOX1

2.69e-052181223281318
Pubmed

Chronic administration of XBD173 ameliorates cognitive deficits and neuropathology via 18 kDa translocator protein (TSPO) in a mouse model of Alzheimer's disease.

GABRD TSPO

2.69e-052181237891168
Pubmed

MUC4-induced nuclear translocation of β-catenin: a novel mechanism for growth, metastasis and angiogenesis in pancreatic cancer.

CTNNB1 MUC4

2.69e-052181224374017
Pubmed

Dual oxidase 1 and NADPH oxidase 2 exert favorable effects in cervical cancer patients by activating immune response.

DUOX2 DUOX1

2.69e-052181231706280
Pubmed

Structures of collagen IV globular domains: insight into associated pathologies, folding and network assembly.

COL4A2 COL4A4

2.69e-052181230443360
Pubmed

A novel human actin-binding protein homologue that binds to platelet glycoprotein Ibalpha.

FLNB FLNC

2.69e-05218129694715
Pubmed

Dual oxidase-2 has an intrinsic Ca2+-dependent H2O2-generating activity.

DUOX2 DUOX1

2.69e-052181215972824
Pubmed

Regulation of MT1-MMP activity by β-catenin in MDCK non-cancer and HT1080 cancer cells.

CTNNB1 MMP14

2.69e-052181220589835
Pubmed

Conserved cysteine residues provide a protein-protein interaction surface in dual oxidase (DUOX) proteins.

DUOX2 DUOX1

2.69e-052181223362256
Pubmed

Activation of dual oxidases Duox1 and Duox2: differential regulation mediated by camp-dependent protein kinase and protein kinase C-dependent phosphorylation.

DUOX2 DUOX1

2.69e-052181219144650
Pubmed

Expression of nicotinamide adenine dinucleotide phosphate oxidase flavoprotein DUOX genes and proteins in human papillary and follicular thyroid carcinomas.

DUOX2 DUOX1

2.69e-052181211762710
Pubmed

Characterization of ThOX proteins as components of the thyroid H(2)O(2)-generating system.

DUOX2 DUOX1

2.69e-052181211822874
Pubmed

Dual oxidase 1 and 2 expression in airway epithelium of smokers and patients with mild/moderate chronic obstructive pulmonary disease.

DUOX2 DUOX1

2.69e-052181218177232
Pubmed

Ketamine, but not phencyclidine, selectively modulates cerebellar GABA(A) receptors containing alpha6 and delta subunits.

GABRD GABRA6

2.69e-052181218480294
Pubmed

Influence of β-catenin small interfering RNA on human osteosarcoma cells.

CTNNB1 MMP14

2.69e-052181221671177
Pubmed

α6-Containing GABAA Receptors Are the Principal Mediators of Inhibitory Synapse Strengthening by Insulin in Cerebellar Granule Cells.

GABRD GABRA6

2.69e-052181226134650
Pubmed

Dual oxidases represent novel hydrogen peroxide sources supporting mucosal surface host defense.

DUOX2 DUOX1

2.69e-052181212824283
Pubmed

Tonic inhibition of accumbal spiny neurons by extrasynaptic α4βδ GABAA receptors modulates the actions of psychostimulants.

GABRD GABRA4

2.69e-052181224431441
Pubmed

Altered markers of tonic inhibition in the dorsolateral prefrontal cortex of subjects with schizophrenia.

GABRD GABRA4

2.69e-052181219289452
Pubmed

Identification of phostensin, a PP1 F-actin cytoskeleton targeting subunit.

PPP1CA PPP1R18

2.69e-052181217374523
Pubmed

Congenital Hypothyroidism due to Oligogenic Mutations in Two Sudanese Families.

DUOX2 DUOX1

2.69e-052181230375286
Pubmed

Expression of collagen VI α5 and α6 chains in human muscle and in Duchenne muscular dystrophy-related muscle fibrosis.

COL6A6 COL6A5

2.69e-052181222226732
Pubmed

Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family.

DUOX2 DUOX1

2.69e-052181210806195
Pubmed

Tyrosine cross-linking of extracellular matrix is catalyzed by Duox, a multidomain oxidase/peroxidase with homology to the phagocyte oxidase subunit gp91phox.

DUOX2 DUOX1

2.69e-052181211514595
Pubmed

Roles of DUOX-mediated hydrogen peroxide in metabolism, host defense, and signaling.

DUOX2 DUOX1

2.69e-052181224161126
Pubmed

Modifications in a flexible surface loop modulate the isozyme-specific properties of mammalian alkaline phosphatases.

ALPL ALPP

2.69e-05218128244974
Pubmed

A new naturally occurring GABA(A) receptor subunit partnership with high sensitivity to ethanol.

GABRD GABRA4

2.69e-052181217159992
Pubmed

The limits of promiscuity: isoform-specific dimerization of filamins.

FLNB FLNC

2.69e-052181212525170
Pubmed

Expression of reduced nicotinamide adenine dinucleotide phosphate oxidase (ThoX, LNOX, Duox) genes and proteins in human thyroid tissues.

DUOX2 DUOX1

2.69e-052181211443211
Pubmed

Purification of a novel flavoprotein involved in the thyroid NADPH oxidase. Cloning of the porcine and human cdnas.

DUOX2 DUOX1

2.69e-052181210601291
Pubmed

Profound desensitization by ambient GABA limits activation of δ-containing GABAA receptors during spillover.

GABRD GABRA6

2.69e-052181221228184
Pubmed

Neurosteroids promote phosphorylation and membrane insertion of extrasynaptic GABAA receptors.

GABRD GABRA4

2.69e-052181224778259
Pubmed

Mammalian alkaline phosphatase catalysis requires active site structure stabilization via the N-terminal amino acid microenvironment.

ALPL ALPP

2.69e-052181216893177
Pubmed

Expression of the collagen VI α5 and α6 chains in normal human skin and in skin of patients with collagen VI-related myopathies.

COL6A6 COL6A5

2.69e-052181220882040
Pubmed

The extracellular A-loop of dual oxidases affects the specificity of reactive oxygen species release.

DUOX2 DUOX1

2.69e-052181225586178
Pubmed

α4βδ GABA(A) receptors are high-affinity targets for γ-hydroxybutyric acid (GHB).

GABRD GABRA4

2.69e-052181222753476
Pubmed

Inhibition of β-catenin dependent WNT signalling upregulates the transcriptional repressor NR0B1 and downregulates markers of an A9 phenotype in human embryonic stem cell-derived dopaminergic neurons: Implications for Parkinson's disease.

NR0B1 CTNNB1

2.69e-052181234941945
Pubmed

Conditional deletion of Neurexin-2 alters neuronal network activity in hippocampal circuitries and leads to spontaneous seizures.

NRXN2 EMX1

2.69e-052181236941261
Pubmed

Shank3 Exons 14-16 Deletion in Glutamatergic Neurons Leads to Social and Repetitive Behavioral Deficits Associated With Increased Cortical Layer 2/3 Neuronal Excitability.

SHANK3 EMX1

2.69e-052181231649512
Pubmed

Differential regulation of dual NADPH oxidases/peroxidases, Duox1 and Duox2, by Th1 and Th2 cytokines in respiratory tract epithelium.

DUOX2 DUOX1

2.69e-052181216111680
Pubmed

Tumour Suppressor Neuron Navigator 3 and Matrix Metalloproteinase 14 are Co-expressed in Most Melanomas but Downregulated in Thick Tumours.

NAV3 MMP14

2.69e-052181236883877
Pubmed

Increased seizure susceptibility and cortical malformation in beta-catenin mutant mice.

CTNNB1 EMX1

2.69e-052181215219872
Pubmed

The canonical Wnt pathway regulates the metastasis-promoting mucin MUC4 in pancreatic ductal adenocarcinoma.

CTNNB1 MUC4

2.69e-052181226526617
Pubmed

Nox/Duox family of nicotinamide adenine dinucleotide (phosphate) oxidases.

DUOX2 DUOX1

2.69e-052181211753072
Pubmed

Silencing of DUOX NADPH oxidases by promoter hypermethylation in lung cancer.

DUOX2 DUOX1

2.69e-052181218281478
Pubmed

Structural and functional characterization of the two human ThOX/Duox genes and their 5'-flanking regions.

DUOX2 DUOX1

2.69e-052181215062544
Pubmed

Regulated hydrogen peroxide production by Duox in human airway epithelial cells.

DUOX2 DUOX1

2.69e-052181215677770
Pubmed

Mucosal reactive oxygen species are required for antiviral response: role of Duox in influenza a virus infection.

DUOX2 DUOX1

2.69e-052181224128054
Pubmed

Biallelic mutations in FLNB cause a skeletal dysplasia with 46,XY gonadal dysgenesis by activating β-catenin.

FLNB CTNNB1

2.69e-052181229095481
Pubmed

MAGI3 negatively regulates Wnt/β-catenin signaling and suppresses malignant phenotypes of glioma cells.

MAGI3 CTNNB1

2.69e-052181226452219
Pubmed

TNAP limits TGF-β-dependent cardiac and skeletal muscle fibrosis by inactivating the SMAD2/3 transcription factors.

SGCA ALPL ALPP

2.95e-0512181331289197
Pubmed

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

SPTLC2 PDK4 CPS1 ABCA9 LDHD FASN MECR HIBCH GLDC AFG3L2 TSPO LIPT2 PISD ELN PCCB ATPAF1

3.01e-059261811620877624
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

COL4A2 COL4A4 COL6A6 COL27A1 COL6A5 ELN MUC4

3.90e-05175181728071719
Pubmed

Semaphorin 4C and 4G are ligands of Plexin-B2 required in cerebellar development.

SEMA4F SEMA4C GABRA6

6.02e-0515181321122816
Pubmed

Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus.

CELSR1 EMX1 MDGA1

6.02e-0515181320473291
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

ATF5 TAF1C GLIS3 REL ZNF688 HOXB8 GTF2H3 DACH2 HOXD12 NFATC4 CTNNB1 EMX1 RAI1 ZNF513 FOXE3

6.02e-058771811520211142
Pubmed

Bone marrow sinusoidal endothelium controls terminal erythroid differentiation and reticulocyte maturation.

STAB2 CTNNB1

8.05e-053181234845225
Pubmed

Targeted disruption of the GABA(A) receptor delta subunit gene leads to an up-regulation of gamma 2 subunit-containing receptors in cerebellar granule cells.

GABRD GABRA6

8.05e-053181211136737
Pubmed

Identification of two new members of the CSMD gene family.

CSMD2 CSMD3

8.05e-053181212906867
Pubmed

Identification and functional characterization of a novel human misshapen/Nck interacting kinase-related kinase, hMINK beta.

MINK1 CTNNB1

8.05e-053181215469942
Pubmed

PDZD7 is a modifier of retinal disease and a contributor to digenic Usher syndrome.

PDZD7 USH2A

8.05e-053181220440071
Pubmed

SOX30, a target gene of miR-653-5p, represses the proliferation and invasion of prostate cancer cells through inhibition of Wnt/β-catenin signaling.

SOX30 CTNNB1

8.05e-053181231889959
Pubmed

NADPH oxidase DUOX1 and DUOX2 but not NOX4 are independent predictors in hepatocellular carcinoma after hepatectomy.

DUOX2 DUOX1

8.05e-053181221915726
Pubmed

Idiopathic Restrictive Cardiomyopathy Is Primarily a Genetic Disease.

FLNC MYBPC3

8.05e-053181227339502
Pubmed

CBX8 Exhibits Oncogenic Activity via AKT/β-Catenin Activation in Hepatocellular Carcinoma.

CTNNB1 CBX8

8.05e-053181229066512
Pubmed

Filamin A and Filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact.

FLNB FLNC

8.05e-053181212393796
Pubmed

DAX1 promotes cervical cancer cell growth and tumorigenicity through activation of Wnt/β-catenin pathway via GSK3β.

NR0B1 CTNNB1

8.05e-053181229497051
Pubmed

Cellular expression, localization and interactions of the product of the human MOST-1 gene associated with breast and prostate cancers.

TSPO FTL

8.05e-053181217143515
Pubmed

SOX30 Inhibits Tumor Metastasis through Attenuating Wnt-Signaling via Transcriptional and Posttranslational Regulation of β-Catenin in Lung Cancer.

SOX30 CTNNB1

8.05e-053181229739711
Pubmed

Extrasynaptic GABA(A) receptors couple presynaptic activity to postsynaptic inhibition in the somatosensory thalamus.

GABRD GABRA4

8.05e-053181224027285
Pubmed

PRC1 components exhibit different binding kinetics in Polycomb bodies.

PRC1 CBX8

8.05e-053181224460908
Pubmed

Genomic structure and fine mapping of the two human filamin gene paralogues FLNB and FLNC and comparative analysis of the filamin gene family.

FLNB FLNC

8.05e-053181211153914
Pubmed

The defect seen in the phosphatidylinositol hydrolysis pathway in HIV-infected lymphocytes and lymphoblastoid cells is due to inhibition of the inositol 1,4,5-trisphosphate 1,3,4,5-tetrakisphosphate 5-phosphomonoesterase.

ALPL ALPP

8.05e-05318121321014
Pubmed

Physical and functional crosstalk between Fanconi anemia core components and the GINS replication complex.

FANCF GINS2

8.05e-053181221109493
Pubmed

Shank3 Binds to and Stabilizes the Active Form of Rap1 and HRas GTPases via Its NTD-ANK Tandem with Distinct Mechanisms.

RAP1GAP SHANK3

8.05e-053181231879129
Pubmed

Filamins as integrators of cell mechanics and signalling.

FLNB FLNC

8.05e-053181211252955
Pubmed

Collagen types in various layers of the human aorta and their changes with the atherosclerotic process.

COL4A2 COL4A4

8.05e-05318123089234
Pubmed

NADPH oxidase-dependent acid production in airway epithelial cells.

DUOX2 DUOX1

8.05e-053181215210697
Pubmed

Synaptic pruning in the female hippocampus is triggered at puberty by extrasynaptic GABAA receptors on dendritic spines.

GABRD GABRA4

8.05e-053181227136678
Pubmed

Role of nicotinamide adenine dinucleotide phosphate oxidase in mediating vesicant-induced interleukin-6 secretion in human airway epithelial cells.

DUOX2 DUOX1

8.05e-053181224164541
Pubmed

Modulation of GABAA receptor signaling increases neurogenesis and suppresses anxiety through NFATc4.

NFATC4 GABRA4

8.05e-053181224948817
Pubmed

DUOX enzyme activity promotes AKT signalling in prostate cancer cells.

DUOX2 DUOX1

8.05e-053181223225414
Pubmed

Spatiotemporal specificity of GABAA receptor-mediated regulation of adult hippocampal neurogenesis.

GABRD GABRA4

8.05e-053181221722213
Pubmed

Assembly rules for GABAA receptor complexes in the brain.

GABRD GABRA6

8.05e-053181228816653
Pubmed

Association of duoxes with thyroid peroxidase and its regulation in thyrocytes.

DUOX2 DUOX1

8.05e-053181219952225
Pubmed

Sustained generation of neurons destined for neocortex with oxidative metabolic upregulation upon filamin abrogation.

FLNB EMX1

8.05e-053181238989458
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

GABRD ZNF609 R3HDM2 OAZ1 SYBU KIFAP3 MEGF8 NR0B1 CHRD R3HDM1 UBE2E3 MIEF2

8.95e-056081811216713569
Pubmed

Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.

PDK4 SYBU CPS1 TRMT2B HPDL LDHD RPIA MECR HIBCH GLDC AFG3L2 TSPO LIPT2 PISD PCCB MIEF2 ATPAF1

9.97e-0511361811734800366
GeneFamilyCollagens

COL4A2 COL4A4 COL6A6 COL27A1 COL6A5

1.11e-05461165490
GeneFamilyGamma-aminobutyric acid type A receptor subunits

GABRD GABRA4 GABRA6

2.31e-04191163563
GeneFamilyFibronectin type III domain containing|USH2 complex

PDZD7 USH2A

2.43e-04411621244
GeneFamilyAlkaline phosphatases

ALPL ALPP

2.43e-04411621072
CoexpressionGSE2405_0H_VS_1.5H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN

PCNX3 TAF1C FBRS ANGPTL1 GGCX TBC1D10C FANCF ZNRF1 ATPAF1 RAI1 TBX6

1.41e-0719918011M6211
CoexpressionNABA_BASEMENT_MEMBRANES

COL4A2 COL4A4 COL6A6 COL6A5 USH2A

7.82e-06401805M5887
CoexpressionNABA_MATRISOME

COL4A2 COL4A4 SEMA4F TMPRSS15 ADAMTS4 COL6A6 PRSS12 NTF4 COL27A1 EMID1 MMP27 COL6A5 ANGPTL1 SEMA4C MEGF8 CHRD LTB ELN MMP14 USH2A MUC4

8.33e-06102618021M5889
CoexpressionGSE3982_EOSINOPHIL_VS_MAST_CELL_UP

PELI1 GAL3ST4 ITGAL ABCA7 USP19 DMC1 CHRD MSLN SLC27A3

1.02e-051991809M5397
CoexpressionNABA_COLLAGENS

COL4A2 COL4A4 COL6A6 COL27A1 COL6A5

1.13e-05431805MM17060
CoexpressionNABA_COLLAGENS

COL4A2 COL4A4 COL6A6 COL27A1 COL6A5

1.26e-05441805M3005
CoexpressionGSE21033_CTRL_VS_POLYIC_STIM_DC_6H_DN

R3HDM2 ITGAL ANGPTL1 GGCX TBC1D10C MEGF8 ZNRF1 R3HDM1

1.35e-051571808M7733
CoexpressionNABA_MATRISOME

COL4A2 COL4A4 SEMA4F TMPRSS15 ADAMTS4 COL6A6 PRSS12 NTF4 COL27A1 EMID1 MMP27 COL6A5 ANGPTL1 SEMA4C MEGF8 CHRD LTB ELN MMP14 MUC4

2.16e-05100818020MM17056
CoexpressionGSE8515_IL1_VS_IL6_4H_STIM_MAC_DN

GABRD SGCA SOX30 PIDD1 SYBU USP19 USH2A TBX6

6.15e-051941808M5767
CoexpressionAtlasfacebase_RNAseq_e14.5_palate_poster_nasal_Tgfbr2_WT_2500_K2

ZMYND15 FLNB FLNC MBTPS1 RAP1GAP ADAMTS4 COL6A6 COL27A1 OAZ1 NXN MAMDC4 SHANK3 GGCX TYRO3 LDHD FASN NFATC4 HECW2 NAV3 DCHS1 FTL ELN MMP14 MDGA1 CBX8 RAI1 SLC27A3 ALPL

1.17e-06122817728facebase_RNAseq_e14.5_palate_poster_nasal_Tgfbr2_WT_2500_K2
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STAB2 EMID1 GLIS3 DUOX2 NXN CELSR1 UBE2E2 NRXN2 SLC45A3 NAV3

5.53e-0919017910f50b9814a1beac67dc042a8c27dfd085ceeda3a6
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STAB2 EMID1 GLIS3 DUOX2 NXN CELSR1 UBE2E2 NRXN2 SLC45A3 NAV3

5.53e-0919017910a22a510b4a257eb0eaf09c7ae7978d3d2f07a58c
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STAB2 EMID1 GLIS3 DUOX2 NXN CELSR1 UBE2E2 NRXN2 SLC45A3 NAV3

5.53e-091901791057c136bf6d7feafb4a220877bed0cc8fdf314db2
ToppCellfacs-Marrow-T_cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATF5 MINK1 MAMDC4 SLC6A1 TYRO3 NAV3 DCHS1 NXPH4 GABRA4

1.47e-081561799758f57dc10fc5cad200bf5b310c10ec9b1405f23
ToppCellfacs-Marrow-T_cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATF5 MINK1 MAMDC4 SLC6A1 TYRO3 NAV3 DCHS1 NXPH4 GABRA4

1.47e-0815617995caefdc6cc86f2ac52abe8c8da821db14f476915
ToppCellfacs-Lung-Endomucin-24m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS15 NWD1 STAB2 EMID1 NXN CELSR1 SLC45A3 NAV3 MMP14

4.19e-081761799057d2759fdc67176c25802b57a78064d8cc93205
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS15 NWD1 STAB2 EMID1 NXN CELSR1 SLC45A3 NAV3 MMP14

4.19e-081761799b81e5d23b31cefc8d374ef403e21acc390c14a80
ToppCellP28-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FLNC STAB2 EMID1 DUOX2 NXN CELSR1 SLC45A3 LTB MMP14

4.40e-081771799e96a7e4544710aaab8bd2800ecff9667880a8bf4
ToppCellP28-Endothelial-lymphatic_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FLNC STAB2 EMID1 DUOX2 NXN CELSR1 SLC45A3 LTB MMP14

4.40e-0817717996e330aa3c87fd640526b746a9deb3b2250d2518c
ToppCelldroplet-Lung-nan-21m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 EMID1 GLIS3 DUOX2 NXN CELSR1 NRXN2 SLC45A3 NAV3

6.43e-0818517993a4ae836e882e8d29eb0a2dfab5677f10f2d365f
ToppCelldroplet-Lung-nan-21m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 EMID1 GLIS3 DUOX2 NXN CELSR1 NRXN2 SLC45A3 NAV3

6.43e-081851799224f0b022c21dd40bf1f7503f00b3107ef958975
ToppCell3'-Adult-Appendix-Epithelial-mature_enterocytic-Colonocyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZMYND15 COL4A4 NWD1 SH3BGR TAF1C CPS1 GTF2H3 HIBCH

5.90e-07176179823fa02d4c39e0b8faa1658116d50b6233a952ccc
ToppCell3'-Adult-Appendix-Epithelial-mature_enterocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZMYND15 COL4A4 NWD1 SH3BGR TAF1C CPS1 GTF2H3 HIBCH

5.90e-07176179830adf8f1638c6244586f8101c2590bb964dfae00
ToppCell10x3'2.3-week_12-13-Mesenchymal_myocytic-stroma-muscle|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

GABRD COL4A2 FLNC SGCA TYRO3 FAM218A OTUD7A ELN

8.61e-0718517980094f9baddb20214d2a2c166f1637d1a9cf1169a
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_3|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ATF5 PELI1 MAGI3 GAL3ST4 SLC18B1 HIBCH CHPF2 ALPL

9.33e-071871798689b3cc76f1e04bd35a7d3ce19e9f08744a7835b
ToppCelldroplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNC STAB2 EMID1 NXN CELSR1 SLC45A3 NAV3 MMP14

1.05e-061901798e80d66ba0d5c263e94c1ab0b89d1dc7b837af3e1
ToppCelldroplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNC STAB2 EMID1 NXN CELSR1 SLC45A3 NAV3 MMP14

1.05e-061901798f32d66c0e74e0a2a23ecb857c4daf0d8573a806c
ToppCelldroplet-Lung-18m-Endothelial-lymphatic_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNC STAB2 EMID1 NXN CELSR1 SLC45A3 NAV3 MMP14

1.05e-061901798b79ffd05806244a9790cd04c66fb4f92c824e69f
ToppCellfacs-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC STAB2 EMID1 DUOX2 NXN CELSR1 SLC45A3 NAV3

1.09e-06191179848823a97c38263f2c6e58348214f5b62773a6368
ToppCelldroplet-Lung-30m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNC STAB2 EMID1 NXN GGCX NRXN2 SLC45A3 NAV3

1.09e-06191179851cff0594ac7ad8c065c8ea2301f8c149bd062b4
ToppCelldroplet-Lung-30m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNC STAB2 EMID1 NXN GGCX NRXN2 SLC45A3 NAV3

1.09e-061911798a55b6f0a7ec1a8852ffca593cfdccd7edea09b7b
ToppCellfacs-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC STAB2 EMID1 DUOX2 NXN CELSR1 SLC45A3 NAV3

1.09e-0619117980eedc66e967b1837ce2c14f8c14b3c1eba868c76
ToppCelldroplet-Lung-30m-Endothelial-lymphatic_endothelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNC STAB2 EMID1 NXN GGCX NRXN2 SLC45A3 NAV3

1.09e-06191179838681a1b182d6af5cce85db5431b6eba4b20ad96
ToppCellCOVID-19-kidney-FLT1+PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

COL4A2 ADAMTS4 PELI1 NXN SHANK3 HECW2 FTL CTNNB1

1.18e-061931798479abb1cd2eb978b8a4fdb900069a6329fc8cade
ToppCellAT1-AT2_cells|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 COL4A4 MAGI3 NXN ABCA7 AATK MSLN ALPP

1.43e-061981798a5b3617ea2ed4bffba59edcf6284799c2b3bbb29
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FLNB PRSS12 MAGI3 NXN CELSR1 SEL1L3 ZNRF1 MUC4

1.43e-0619817981408e02e053ad3406229bfe8189da03be6366e81
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

RAP1GAP SYBU CSMD2 SLC6A1 FASN NRXN2 R3HDM1 MDGA1

1.54e-0620017985c7263c862093ad9dbc81d06b16b6f74e8a6b634
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.

RAP1GAP SYBU CSMD2 SLC6A1 FASN NRXN2 R3HDM1 MDGA1

1.54e-06200179861d7dd0a78942b069c3f5e75044368dc00e6e8e6
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-MyoFB-3|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ZNF536 SYT3 SH3BGR NXN UBE2E2 GMPPA SLC27A3

1.69e-0614117977ae8ead02e5aeb4106c4a30c08a7a061da3a5d6a
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular-6|TCGA-Stomach / Sample_Type by Project: Shred V9

ZMYND15 FLNB AKAP8 PCNX3 SPTLC2 HPDL MUC4

3.76e-061591797655c0749c238bd68cb797adb83e25a23b8a3cc9d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLNC STAB2 ADAMTS4 NXN HECW2 ELN SLC27A3

4.25e-0616217972ac02523348660e514d464f8f2434ee0c312d784
ToppCellAdult-Mesenchymal-myofibroblast_cell-D231|Adult / Lineage, Cell type, age group and donor

ZNF536 ABCA9 SEMA4C DMC1 DCHS1 TIGD5 ELN

4.61e-0616417973d8ff70fe5582d1fb56b338be8b76fa1428b3657
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STAB2 EMID1 DUOX2 SHANK3 NRXN2 SLC45A3 NAV3

4.80e-061651797347b59aa625a8a960828b8620824d8ac48990e07
ToppCellPND03-Endothelial-Endothelial_lymphatic|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STAB2 EMID1 DUOX2 SHANK3 NRXN2 SLC45A3 NAV3

4.80e-0616517971890f9c33b0c5b381d57f97042da2610a093a6de
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STAB2 EMID1 DUOX2 SHANK3 NRXN2 SLC45A3 NAV3

4.80e-061651797507c89ece0a336b8e9c65b79889a714e17ddca27
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STAB2 EMID1 DUOX2 SHANK3 NRXN2 SLC45A3 NAV3

4.80e-06165179739a25be081a5d59c7cf107a997d352793d5025fb
ToppCellICU-SEP-Lymphocyte-T_NK-dnT|ICU-SEP / Disease, Lineage and Cell Type

BEX5 MBLAC1 FASN TRMT44 GINS2 MMP14 MDGA1

5.00e-06166179796d92316cee20b722fe782db9dafcceb8f2c220b
ToppCellPosterior_cortex-Macroglia-ASTROCYTE-Gja1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

NWD1 PDK4 GLIS3 PAQR6 CELSR1 GLDC

6.15e-061121796e30cd0b7b755c63081bbeed4e1a884b6640d34f8
ToppCellPosterior_cortex-Macroglia-ASTROCYTE|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

NWD1 PDK4 GLIS3 PAQR6 CELSR1 GLDC

6.15e-0611217961c0bcc6c972c50a9d950cd56b65efb8d778ec25a
ToppCellfacs-MAT-Fat-18m-Lymphocytic-T_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4F TBC1D10C DACH2 ZNRF1 LSS LTB RINL

6.55e-06173179797391a763c17ce0107c9e2386e88c417ac75a72e
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-Alox5+_Lymphocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 SYT3 DCDC2B TBC1D10C LTB PCCB MSLN

6.55e-0617317974c788c1dad1da495b3b5c10f95e779848dfe85dc
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-lymphocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 SYT3 DCDC2B TBC1D10C LTB PCCB MSLN

6.55e-0617317976e92983d9f8a2a37f23e60a0d5bb1738217897bc
ToppCellP15-Endothelial-lymphatic_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

STAB2 EMID1 DUOX2 NXN SLC45A3 LTB MMP14

7.06e-061751797a00c6fa9b33640710dd05a3799031147196f0986
ToppCellP15-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

STAB2 EMID1 DUOX2 NXN SLC45A3 LTB MMP14

7.06e-06175179784d252f3e432231687613299bbea14978bb4b06b
ToppCellsevere-B_memory|World / disease stage, cell group and cell class

COL4A4 PELI1 REL SYBU ARID5B SEL1L3 LTB

7.33e-0617617974e5c6b1aa5ffd13593a6bcd1e1253c1737c5c2b4
ToppCellHealthy-B_memory|World / disease group, cell group and cell class

COL4A4 SYBU ANGPTL1 ARID5B SEL1L3 LTB NXPH4

7.89e-061781797b4848b95f2b449c9fac9b5560d959af1788a6f3b
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAP1GAP LRRC24 EMID1 ANGPTL1 NRXN2 NAV3 MMP14

8.49e-061801797907cd510fd2e21532ce04ba687e8894f7af71f27
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RBM45 PDK4 PAQR6 CFAP210 TRMT44 ELN ALPL

8.49e-061801797e9785ac2806103f725f5a5208495826354ec6e22
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAP1GAP LRRC24 EMID1 ANGPTL1 NRXN2 NAV3 MMP14

8.49e-061801797fa819df81fca95c2cc602fede635cb03e3f35fad
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OAZ1 PPP1CA TBC1D10C PPP1R18 FTL LTB RINL

8.49e-061801797de87503d9caac3ebc80ab8090c1a9ee5a925b2a0
ToppCellHealthy-B_memory|Healthy / disease group, cell group and cell class

COL4A4 SYBU ANGPTL1 ARID5B SEL1L3 LTB NXPH4

8.80e-0618117977b903076efb90026b9845af0c7a840901451193a
ToppCellAT1-AT2_cells-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 COL4A4 MAGI3 SYBU ABCA7 MSLN ALPP

8.80e-061811797ca23ce4f2c7b684d8ddd0e8619b3b696023d75e3
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STAB2 EMID1 NXN CELSR1 SLC45A3 NAV3 MMP14

9.12e-0618217972cc434e46985c66fc36de05344a67aa96d90abc9
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STAB2 EMID1 NXN CELSR1 SLC45A3 NAV3 MMP14

9.12e-0618217970cde2775bdaaa2172499925bd59b0ac2d545eb27
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STAB2 EMID1 NXN CELSR1 SLC45A3 NAV3 MMP14

9.12e-0618217973e7457b2a70b45735fb75d6617b7f34cef28758e
ToppCelldroplet-Lung-LUNG-1m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAP1GAP FOXO6 NTF4 LDHD FASN CELSR1 SEL1L3

9.12e-061821797c1e0be27064e14043b78ae501b02d4e9542267a3
ToppCelldroplet-Lung-LUNG-1m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAP1GAP FOXO6 NTF4 LDHD FASN CELSR1 SEL1L3

9.12e-0618217973c9b4869d357884ae4bcd22a9872faf83a5cfc6d
ToppCellP03-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

STAB2 EMID1 DUOX2 CELSR1 NRXN2 SLC45A3 LTB

9.45e-06183179789727b4f65949ed2dce9d2e0228c79fe4280230c
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l44-58|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PTX4 FOXO6 PRSS12 CCDC142 AATK SEL1L3 CARNS1

9.45e-061831797dc9602bed3136db91faeffef177006246dc92743
ToppCellP03-Endothelial-lymphatic_endothelial_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

STAB2 EMID1 DUOX2 CELSR1 NRXN2 SLC45A3 LTB

9.45e-061831797113e6d8d4bb271be984af06cd6c22b180425dcfc
ToppCelldroplet-Limb_Muscle-nan-18m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4F ZNF536 RAP1GAP PAQR6 CSMD3 LDHD AATK

9.80e-061841797a7399a72f065d68800e3e0b2031d9894e0cc0ba4
ToppCelldroplet-Lung-1m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RAP1GAP FOXO6 NTF4 LDHD FASN CELSR1 SEL1L3

9.80e-06184179724cbe9f2461ea920954e44bf3b2c2a6a5d4debfb
ToppCelldroplet-Lung-1m-Epithelial-alveolar_epithelial-type_II_pneumocyte|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RAP1GAP FOXO6 NTF4 LDHD FASN CELSR1 SEL1L3

9.80e-06184179798079fd048a63b51bbdf3833b6f15bf0ae99ea90
ToppCellPericytes-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 FLNC ADAMTS4 SGCA CPS1 CHRD ELN

9.80e-0618417973d2d55d0f22874be21665ab37da710482f77fc36
ToppCelldroplet-Lung-1m-Epithelial-alveolar_epithelial|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RAP1GAP FOXO6 NTF4 LDHD FASN CELSR1 SEL1L3

9.80e-06184179786c1551c4f7c7d0c35c14852b01b1e602fa5092a
ToppCellEndothelial-B-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 FLNB FLNC STAB2 ADAMTS4 GLDC ELN

1.01e-051851797133c9dc64d564dae4aeeeca22f386aa3f13fa980
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-2|TCGA-Kidney / Sample_Type by Project: Shred V9

GABRD COL4A2 ADAMTS4 SGCA HECW2 DCHS1 ELN

1.05e-0518617971e6526fc9e9381b7ace864588cc7bd80194338d6
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC STAB2 EMID1 NXN NRXN2 SLC45A3 NAV3

1.05e-0518617970de87109da9324c597fadf2eb782f0f158afe832
ToppCelldroplet-Lung-LUNG-30m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC STAB2 EMID1 NXN NRXN2 SLC45A3 NAV3

1.05e-051861797f23f21781a758541f59c06efa7739d26a03fb478
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D175|Adult / Lineage, Cell type, age group and donor

FLNC STAB2 ADAMTS4 EMID1 SHANK3 HECW2 ELN

1.09e-0518717971e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCellAdult-Epithelial-club_cell-D231|Adult / Lineage, Cell type, age group and donor

PRSS12 GLIS3 NXN SLC6A1 CELSR1 SEL1L3 MUC4

1.09e-051871797ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCelldroplet-Fat-Scat-21m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC ATF5 COL6A5 DUOX1 SEL1L3 ELN MMP14

1.13e-0518817977fc9810ab14354cb512e2b1285562009c10203f5
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_memory-B_memory-0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

COL4A4 PELI1 REL SYBU SEL1L3 LTB NXPH4

1.13e-051881797229108e7e3db49e1cfd747d69e338394139d95b3
ToppCelldroplet-Lung-nan-18m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC STAB2 EMID1 NXN CELSR1 SLC45A3 NAV3

1.13e-051881797a6ed43fdd42d681c9fbb2fb368947ab7e41d8d7c
ToppCelldroplet-Lung-nan-18m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC STAB2 EMID1 NXN CELSR1 SLC45A3 NAV3

1.13e-05188179754550313db78b3b5b572fa1e67092c8f6f33aab5
ToppCelldroplet-Limb_Muscle-nan-18m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4F ZNF536 RAP1GAP PAQR6 CSMD3 LDHD AATK

1.13e-051881797cb9d0b48e2fd9cc576132803273b9c0382900944
ToppCelldroplet-Fat-Scat-21m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC ATF5 COL6A5 DUOX1 SEL1L3 ELN MMP14

1.13e-051881797e54e09d34e263d5709c337914809e61e74e20591
ToppCelldroplet-Limb_Muscle-nan-18m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4F ZNF536 RAP1GAP PAQR6 CSMD3 LDHD AATK

1.13e-0518817978385fd384fc55e3b17802bb6698eb93b2c16d7f2
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

COL4A4 SYBU ANGPTL1 CELSR1 SEL1L3 LTB NXPH4

1.13e-0518817975707786cc4452dc34f95db2b3cd29f6e025c0622
ToppCellRA-14._Fibroblast_III|RA / Chamber and Cluster_Paper

COL4A2 COL4A4 ADAMTS4 GLIS3 REL NXN ALPL

1.17e-05189179746e9a58aacd79db5a02898a8c7244e1884adcfd1
ToppCellRA-14._Fibroblast_III|World / Chamber and Cluster_Paper

COL4A2 COL4A4 ADAMTS4 GLIS3 REL NXN ALPL

1.17e-051891797b6e12d24d2b0735730bdc625f8318c1c9c2a9b3b
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-bronchial_smooth_muscle_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A4 FLNC SH3BGR GAL3ST4 SYBU HOXB8 MYBPC3

1.17e-0518917974dc32b463546bbe7250dddd281b92ad17ec22da1
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-Airway_Smooth_Muscle|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A4 FLNC SH3BGR GAL3ST4 SYBU HOXB8 MYBPC3

1.17e-0518917970d06bf0d7191d13a1c4f30a7881e7ea1093bfd6f
ToppCellIPF-Epithelial-Club|IPF / Disease state, Lineage and Cell class

GLIS3 MAGI3 SYBU NXN MUC4 MSLN ALPL

1.17e-051891797f3fcef008ef252b29ac6d567fef27f9acf9cd70f
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNC STAB2 EMID1 DUOX2 NXN CELSR1 SLC45A3

1.21e-05190179726e2237f65cb43723c5da853831b40df2982d6e4
ToppCelldroplet-Limb_Muscle-nan-18m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF536 RAP1GAP COL27A1 EMID1 PAQR6 CSMD3 CARNS1

1.21e-051901797e2481bd5166fde2cdc0c3824894f2bccb8294fdd
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNC STAB2 EMID1 DUOX2 NXN CELSR1 SLC45A3

1.21e-051901797a1514d2186eb4fe569971ab22dc0c17d353fb94a
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNC STAB2 EMID1 DUOX2 NXN CELSR1 SLC45A3

1.21e-0519017970bb954a94317cfc742b9b6221bb80f8baa6d3ff1
ToppCellIPF-Epithelial-Club|World / Disease state, Lineage and Cell class

GLIS3 MAGI3 SYBU NXN CELSR1 MUC4 MSLN

1.25e-0519117973c88a6f1d74bb3b9173cd0ea3a63c6d9570e3954
ToppCellLAM-Epithelial-AT1|Epithelial / Condition, Lineage and Cell class

COL4A2 COL4A4 NXN ABCA7 MIEF2 MSLN ALPP

1.25e-0519117973457e15d1e9b36a78363d46b320c4ec46b40290a
ToppCell10x5'v1-week_14-16-Mesenchymal_fibro-stroma-endosteal_fibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FLNC COL6A6 COL27A1 SYBU ANGPTL1 SLC6A1 ELN

1.25e-05191179744b1f62fdee03b157fe545f2ae6ff84f8929a8ac
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A2 ADAMTS4 COL6A6 GLIS3 COL6A5 ELN MMP14

1.29e-051921797162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCellEpithelial-club_cell|World / Lineage, Cell type, age group and donor

PRSS12 GLIS3 MAGI3 SYBU CELSR1 SEL1L3 MUC4

1.34e-0519317972bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-IPC_like-IPCs|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

NXN PRAG1 ARID5B SEL1L3 EMX1 UBE2E3 NXPH4

1.34e-0519317972088f1d210c73f74685492c63065c62ac3f553e9
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-IPC_like|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

NXN PRAG1 ARID5B SEL1L3 EMX1 UBE2E3 NXPH4

1.34e-051931797f24bae40f5cbcfece04fbefe4e3de1b88ac90de4
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

COL4A4 PELI1 REL ANGPTL1 ARID5B SEL1L3 LTB

1.38e-0519417975cd72330c9d9bb21b6c9d5d35085eade101486d1
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GGCX DMC1 MEGF8 GINS2 LIPT2 R3HDM1 MDGA1

1.38e-0519417970e9830ad070c47acaa952400bf2a3ddbff664a2f
ToppCellwk_20-22-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

NWD1 DCDC2B CFAP210 DUOX1 CELSR1 DNAH12 MUC4

1.38e-051941797756082a0f5953b52229bb60d40b84701cb6cb23d
ToppCell(0)_Myeloid-(00)_Monocyte-(001)_CD16+_Monocyte|(00)_Monocyte / immune cells in Peripheral Blood (logTPM normalization)

PDK4 ITGAL SEMA4C TBC1D10C ARID5B FTL LTB

1.38e-05194179789cb262e04d7105012e957e0add44c73de6c1ed0
ToppCell(0)_Myeloid-(001)_CD16+_Monocyte|(0)_Myeloid / immune cells in Peripheral Blood (logTPM normalization)

PDK4 ITGAL SEMA4C TBC1D10C ARID5B FTL LTB

1.38e-0519417974240d0b3cf264f51dcf0cb4d0a18641d85d38638
Drugvigabatrin

GABRD SLC6A1 TSPO ELN GABRA4 GABRA6

2.37e-06491806CID000005665
Drugflurazepam

GABRD SLC6A1 TSPO GABRA4 GABRA6

7.82e-06351805CID000003393
DrugFlunitrazepam

TSPO GABRA4 GABRA6

9.55e-0661803DB01544
Drugsecobarbital

GABRD SLC6A1 TSPO GABRA4 GABRA6

1.04e-05371805CID000005193
DrugDMCM

GABRD SLC6A1 TSPO GABRA4 GABRA6

1.19e-05381805CID000104999
Drugzaleplon

GABRD SLC6A1 TSPO GABRA4 GABRA6

1.35e-05391805CID000005719
Druggaboxadol

GABRD SLC6A1 TSPO GABRA4 GABRA6

1.74e-05411805CID000003448
Drugbicuculline methochloride

SLC6A1 TSPO GABRA4 GABRA6

2.04e-05211804CID000123659
DrugFenoprofen calcium salt dihydrate [53746-45-5]; Up 200; 7.2uM; PC3; HT_HG-U133A

DGCR2 ZNF609 TAF1C MINK1 SRRT MEGF8 LSS ELN MMP14

2.13e-0519018094274_UP
Drugzolpidem

GABRD SLC6A1 TSPO GABRA4 GABRA6

2.20e-05431805CID000005732
DrugDiethylstilbestrol [56-53-1]; Down 200; 15uM; HL60; HT_HG-U133A

ZNF609 SPTLC2 OAS2 CPS1 SRRT ELN CBX8 GABRA4 TBX6

2.41e-0519318092567_DN
DrugFlumazenil

TSPO GABRA4 GABRA6

2.64e-0581803ctd:D005442
DrugLomefloxacin hydrochloride [98079-52-8]; Up 200; 10.4uM; PC3; HT_HG-U133A

DGCR2 ZNF536 STAB2 EMID1 NR0B1 DCHS1 LSS MMP14 TBX6

2.94e-0519818093723_UP
Drugthymol

GABRD ALPL ALPP GABRA4 GABRA6

3.08e-05461805CID000006989
Drugaspirin, USP; Down 200; 100uM; HL60; HT_HG-U133A

PADI4 PRSS12 TAF1C MINK1 FBRS MEGF8 LSS ELN EMX1

3.19e-0520018092664_DN
Drugisonipecotic acid

SLC6A1 TSPO GABRA4 GABRA6

4.20e-05251804CID000003773
Disease1-ribosyl-imidazoleacetate measurement

CPS1 TIGD5 CARNS1

1.57e-0591713EFO_0800034
DiseaseUsher syndrome type 2A (is_implicated_in)

PDZD7 USH2A

3.34e-0521712DOID:0110838 (is_implicated_in)
DiseaseUSHER SYNDROME, TYPE IIA

PDZD7 USH2A

3.34e-0521712276901
DiseaseUSHER SYNDROME, TYPE IIA

PDZD7 USH2A

3.34e-0521712C1848634
DiseaseUsher syndrome type 2A

PDZD7 USH2A

3.34e-0521712cv:C1848634
Diseasemyofibrillar myopathy 5 (implicated_via_orthology)

FLNB FLNC

9.98e-0531712DOID:0080096 (implicated_via_orthology)
Diseasedistal muscular dystrophy 4 (implicated_via_orthology)

FLNB FLNC

9.98e-0531712DOID:0111190 (implicated_via_orthology)
DiseaseUsher syndrome type 2

PDZD7 USH2A

9.98e-0531712C0339534
Diseasephenylketonuria (implicated_via_orthology)

DUOX2 DUOX1

1.99e-0441712DOID:9281 (implicated_via_orthology)
Diseaseglycine encephalopathy (implicated_via_orthology)

GLDC LIPT2

1.99e-0441712DOID:9268 (implicated_via_orthology)
Diseaseclubfoot (is_implicated_in)

FLNB HOXD12

3.30e-0451712DOID:11836 (is_implicated_in)
DiseaseUsher Syndrome, Type II

PDZD7 USH2A

3.30e-0451712C1568249
Disease3-methylglutaconate measurement

CPS1 GLDC

4.93e-0461712EFO_0800047
Disease2,3-dihydroxy-5-methylthio-4-pentenoate (DMTPA) measurement

CPS1 CARNS1

4.93e-0461712EFO_0800111
Diseasehexanoylglycine measurement

CPS1 GLDC

6.88e-0471712EFO_0800233
Diseaseresponse to platinum based chemotherapy, response to antineoplastic agent

ZNF536 ALPL

6.88e-0471712EFO_0004647, GO_0097327
Diseasealkaline phosphatase measurement

COL4A2 RAP1GAP AKAP8 MINK1 CPS1 PRAG1 SRRT SLC12A9 NFATC4 CHPF2 PCCB UBE2E3 RAI1 ALPL MYBPC3

8.74e-04101517115EFO_0004533
Diseasecommon bile duct neoplasm (is_marker_for)

MUC4 MSLN

9.14e-0481712DOID:4608 (is_marker_for)
DiseaseSarcomatoid Renal Cell Carcinoma

ZNF536 PIDD1 CSMD3 NAV3 MUC4

9.18e-041281715C1266043
DiseaseChromophobe Renal Cell Carcinoma

ZNF536 PIDD1 CSMD3 NAV3 MUC4

9.18e-041281715C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

ZNF536 PIDD1 CSMD3 NAV3 MUC4

9.18e-041281715C1266044
DiseasePapillary Renal Cell Carcinoma

ZNF536 PIDD1 CSMD3 NAV3 MUC4

9.18e-041281715C1306837
DiseaseRenal Cell Carcinoma

ZNF536 PIDD1 CSMD3 NAV3 MUC4

9.18e-041281715C0007134
Diseaseprimary bacterial infectious disease (implicated_via_orthology)

DUOX2 DUOX1

1.17e-0391712DOID:0050338 (implicated_via_orthology)
DiseaseHepatocellular Adenoma

UBE2E2 CTNNB1

1.17e-0391712C0206669
Diseaseaspirin use measurement

COL4A2 MIA3 PCNX3

1.50e-03391713EFO_0007013
DiseaseAutism Spectrum Disorders

SHANK3 NRXN2 USH2A RAI1

1.53e-03851714C1510586
Diseasealanine measurement

LRRC24 PDK4 GLIS3 CPS1

1.60e-03861714EFO_0009765
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

ZNF536 PIDD1 CSMD3 NAV3 MUC4

1.75e-031481715C0279702
Disease3-methylglutarylcarnitine (2) measurement

CPS1 GLDC

1.77e-03111712EFO_0800074
Diseasethrombin generation potential measurement

COL27A1 MYBPC3

1.77e-03111712EFO_0005538
Diseasedecanoylcarnitine measurement

COL27A1 SLC6A1

2.12e-03121712EFO_0021039
DiseaseAL amyloidosis

FBRS CHPF2

2.12e-03121712MONDO_0019438
Diseasecortical thickness

MON2 COL4A2 FLNB ZNF536 PRSS12 GLIS3 SYBU MBLAC1 DUOX1 CELSR1 NAV3 ELN PCCB MIEF2 CBX8

2.15e-03111317115EFO_0004840
DiseaseCongenital Hypothyroidism

GLIS3 DUOX2

2.50e-03131712C0010308
Diseasehypothyroidism (implicated_via_orthology)

DUOX2 DUOX1

2.50e-03131712DOID:1459 (implicated_via_orthology)
Diseasecaudate nucleus measurement, functional brain measurement, response to reward

CSMD3 NXN CELSR1

2.57e-03471713EFO_0007849, EFO_0008387, EFO_0008396
Diseasealcohol consumption measurement, high density lipoprotein cholesterol measurement

R3HDM2 CPS1 DPEP3 PCCB MYBPC3

2.59e-031621715EFO_0004612, EFO_0007878
Diseasemyopathy (implicated_via_orthology)

COL4A4 FLNB FLNC

2.73e-03481713DOID:423 (implicated_via_orthology)
Diseasecongenital hypothyroidism (implicated_via_orthology)

DUOX2 DUOX1

2.90e-03141712DOID:0050328 (implicated_via_orthology)
Diseasethyroid gland papillary carcinoma (is_marker_for)

RAP1GAP CTNNB1

2.90e-03141712DOID:3969 (is_marker_for)
Diseasealcohol drinking, high density lipoprotein cholesterol measurement

R3HDM2 CPS1 DPEP3 PCCB MYBPC3

3.03e-031681715EFO_0004329, EFO_0004612
DiseaseCardiomyopathy, Familial Idiopathic

FASN CTNNB1 PCCB

3.07e-03501713C1449563
Diseasetestosterone measurement

COL4A2 ZNF536 MIA3 EMID1 ZNF629 GLIS3 R3HDM2 CSMD3 FASN UBE2E2 NR0B1 ARID5B USH2A PCCB CBX8 RAI1

3.13e-03127517116EFO_0004908
Diseaseperiprosthetic osteolysis, disease progression measurement

GLIS3 OTUD7A

3.34e-03151712EFO_0008336, EFO_0009761
DiseaseSchizoaffective disorder-bipolar type

STAB2 PURB

3.80e-03161712EFO_0009965
Diseasephosphorus measurement

RAP1GAP ALPL

3.80e-03161712EFO_0004861
DiseaseAutistic Disorder

NTF4 TAF1C CSMD3 SHANK3 NRXN2 GABRA4

4.27e-032611716C0004352
Diseaseschizophrenia, sex interaction measurement

SYBU ABCA9 NAV3

5.14e-03601713EFO_0008343, MONDO_0005090
Diseaseresponse to methotrexate, neurotoxicity

NXN PNPLA6

5.35e-03191712EFO_0011057, GO_0031427
DiseaseSchizophrenia

GABRD DGCR2 CSMD2 SHANK3 PITPNM1 SLC6A1 NRXN2 CTNNB1 MDGA1 RAI1 GABRA4 GABRA6

5.53e-0388317112C0036341

Protein segments in the cluster

PeptideGeneStartEntry
YPFQILLAGQTGPGG

MAMDC4

396

Q6UXC1
PEPFANGIVRGAGYN

CSMD2

2126

Q7Z408
DPGTPLYGIREGDGF

CSMD3

666

Q7Z407
GGVGPGEQPCLRTLY

AFG3L2

26

Q9Y4W6
ELNYVGGRGLGGPSP

AKAP8

226

O43823
GGGEPLGFLGYCPQE

ABCA9

1356

Q8IUA7
GLRGFIGFPGLPGDQ

COL4A4

1036

P53420
RYRGEPGEPGLVGFQ

COL4A2

181

P08572
YFLAGLGLGPGRGRE

CARNS1

51

A5YM72
TLGGRGPSPEGYLVG

CCDC142

706

Q17RM4
PGLLGGNEIQRDPGY

ANGPTL1

231

O95841
SGPNGRLLYTFQGGD

CELSR1

921

Q9NYQ6
TGLAVGLDPQGYGNP

CELSR1

2586

Q9NYQ6
PGAGGYPGGKIIFID

DMC1

146

Q14565
AGVPGGLFRAEPLYS

DACH2

16

Q96NX9
EVRYGGFSLGGRDPG

ABCA7

1411

Q8IZY2
PLAPYEVLGGALEGG

ATF5

36

Q9Y2D1
IGPAFVALIGDQYGP

NWD1

61

Q149M9
RRGIQQLYGGESGFP

MMP14

276

P50281
PQYLGLRPAAAGAGA

NXPH4

31

O95158
FVPGQGDSRYPLLGQ

R3HDM1

921

Q15032
RPGGPAQGDGRYSLL

R3HDM2

796

Q9Y2K5
LQGRPAFPGYGVQDS

RAI1

91

Q7Z5J4
LQPGRPSLGGGVDFY

RAB26

46

Q9ULW5
YPPGNRIGVSFIDDG

RBM45

311

Q8IUH3
LGEVPAAGGSPLRQY

NTF4

121

P34130
AIGLFPDVGGGYFLP

HIBCH

171

Q6NVY1
PDVGGGYFLPRLQGK

HIBCH

176

Q6NVY1
NSRNAPLAGFGYGLP

PDK4

321

Q16654
PATGQNGPRGLYAFG

DUOX1

221

Q9NRD9
IPYEGFASLRGSNGP

HECW2

1506

Q9P2P5
GPFQIIFEGVRGPGY

MDGA1

886

Q8NFP4
IFEGVRGPGYLGDIA

MDGA1

891

Q8NFP4
GPDFGYVTRGPQTGG

PADI4

386

Q9UM07
GRCPRYFDGPLGVLG

MMP27

166

Q9H306
LPERGVSLFPYGAGA

MUC4

4311

Q99102
SGPQDPFSVGRYGGR

DCHS1

2316

Q96JQ0
LGQGDYVFRPGQPDA

PNPLA6

216

Q8IY17
LGLDIGAQGEPLGYR

CTNNB1

696

P35222
YPGGEGHRLSLGFPV

PRSS12

486

P56730
GSVGRLSQFPPYGLG

FOXB2

236

Q5VYV0
GFGYRVGGVGVPAAP

KRT84

121

Q9NSB2
GFGRGPVPGLANFQA

FANCF

71

Q9NPI8
EFPYLGRLREEPGGG

MAGI3

41

Q5TCQ9
PILGLYQIPAEGGGR

MBTPS1

826

Q14703
GGPEAGLGEYLFERL

FTL

156

P02792
GFYISTPTGPGGRQE

TMPRSS15

391

P98073
PALGGGEYQEPGGNV

BEX5

21

Q5H9J7
DPATGQNGPRGLYAF

DUOX2

226

Q9NRD8
GGYNPDLVRAYGPGL

FLNB

641

O75369
AGGYQPLDRRGSGEP

PCNX3

276

Q9H6A9
RGGFYLLPVNGFPEE

PDZD7

671

Q9H5P4
LQAGDAPSLGAGYPR

NAV3

751

Q8IVL0
GLPNRPYTLTGGRHG

FAM218A

41

Q96MZ4
DYDVNITFGGRPIPG

FLNC

1416

Q14315
QAGDPGLVSAYGPGL

FLNC

2501

Q14315
GLLDGAQDAYGPRPA

FOXO6

321

A8MYZ6
GDYGGPLFLLPGLLI

LSS

96

P48449
LYLGGLPEGGRVDLP

NRXN2

626

Q9P2S2
GAFYLNLGGAPEGPA

DNAH12

1241

Q6ZR08
FGGLGLPQGLLGNLY

MEGF8

1526

Q7Z7M0
RFYLLLLGVGDPSGP

MEGF8

2611

Q7Z7M0
LRPPGGGSNFSLGFD

JPT1

21

Q9UK76
RGPPGEGALFVNDYL

LRRC24

436

Q50LG9
SILIGAPGGPAGYLR

PKLR

26

P30613
PLGPATQGGTYRCFG

KIR2DS3

186

Q14952
LDGYDNRLRPGFGGP

GABRA4

56

P48169
EGYDNRLRPGFGGAV

GABRA6

41

Q16445
GLIAGYARNFRPGIG

GABRD

46

O14764
EAARAALQGGGPPYG

MSLN

221

Q13421
TLGLGLQGGIPNGYL

MSLN

581

Q13421
GGEAFAPIPFGGIYL

OTUD7A

331

Q8TE49
GGGVTLLPAFEYRGT

MON2

436

Q7Z3U7
LLALAGGPGFRAEPY

PAQR6

66

Q6TCH4
KPRPFAGGGYRLGAA

NSFL1C

146

Q9UNZ2
FPLVQGVAIGGSYGR

OAS2

51

P29728
GGSLYIEIPGGALPE

OAZ1

136

P54368
VKGYRPQGGGTQLPF

GAL3ST4

116

Q96RP7
PGNFPGANFTLYRGG

HIDE1

41

A8MVS5
TLLERAGYRGPFLPG

HPDL

131

Q96IR7
DLGGRPTVVYGPSSG

HOXB8

31

P17481
YFAQRPGGKEALPGG

NR0B1

176

P51843
GFLPGTAQEYGGIIR

PCCB

396

P05166
GNGPGYVLKDGARPD

ALPP

416

P05187
YGQFSGLNPGGRPIT

PPP1CA

306

P62136
GGYTPRGNSIFGLAP

ALPL

386

P05186
RYLQEFAPLGTGGGL

GMPPA

81

Q96IJ6
YDGILIAGGPGNPAL

CPS1

256

P31327
YLGQAPELLGGAEPG

ADAMTS4

111

O75173
PELLGGAEPGTYLTG

ADAMTS4

116

O75173
GPGAVAAARLYGLEP

FBRS

386

Q9HAH7
SQRPLGEPSAGLGEY

CBX8

211

Q9HC52
DGAIGRQLPAGAPSY

DCDC2B

116

A2VCK2
GAGPAVLQVAGLYRG

ATPAF1

11

Q5TC12
PGSRGAPGQYGEKGF

COL6A5

1496

A8TX70
GVLVAPGGLALPAYG

GLIS3

216

Q8NEA6
PGGLALPAYGEDGAL

GLIS3

221

Q8NEA6
YRQGVPIIPFGTGTG

LDHD

86

Q86WU2
GFSQPYLAGSGPLGL

HOXD12

71

P35452
GPKGSRGYIGLPGLF

COL27A1

751

Q8IZC6
RGYIGLPGLFGLPGS

COL27A1

756

Q8IZC6
LIGDLGVLGPIGYPG

COL27A1

821

Q8IZC6
GDPGYPGQEGVQGLR

COL27A1

1361

Q8IZC6
PCYGALFGPRGVNIG

CRIP3

56

Q6Q6R5
LFGPRGVNIGGVGSY

CRIP3

61

Q6Q6R5
NLGRRIPGFDYGPDG

DGCR2

391

P98153
GGRYLPHGLGEGQPL

MBLAC1

141

A4D2B0
QPGIKFTIPLSGYGG

CEP192

1866

Q8TEP8
QGNYGFLPELPAVGG

MECR

91

Q9BV79
GAGRSLYGGPELVFP

EMX1

106

Q04741
IGLYEPELGSGAGPA

EMID1

396

Q96A84
IGGNYDGTGRFPQGL

DPEP3

356

Q9H4B8
AAPLGQARAVGYPGA

GJA3

276

Q9Y6H8
PFRGYAVLGGERGGP

FASN

466

P49327
AGQFPLGGVAARPGF

ELN

751

P15502
RLFYGVKAGPGVGAP

PPP1R18

451

Q6NYC8
RGPPGFKGSEGYLGE

COL6A6

1406

A6NMZ7
QPVGILGRPATAYGF

KIFAP3

766

Q92845
PGGGLYGELPEGTSI

PURB

211

Q96QR8
EPAGPVYTAGLRGGL

LIPT2

51

A6NK58
PFLGGNRLSLDLYPG

PIDD1

31

Q9HB75
GSRFREGYEIPPGGS

PTX4

386

Q96A99
IVLGYNGSLPNGDRG

PELI1

21

Q96FA3
DLGIYQPGGSGDSIP

MINK1

956

Q8N4C8
FVPGGPLYDGLQAGA

MIEF2

176

Q96C03
YGRVLAPLPGRAGGA

RPIA

11

P49247
KPELYQGTGPGGRRS

SYT3

271

Q9BQG1
GDNTGVFLGGLPRSY

USH2A

1641

O75445
NRGPDGNPKTVGFYL

TRMT2B

161

Q96GJ1
RTGISYPGALLPQGF

TRMT44

6

Q8IYL2
FPGVPGRNQTLAGEY

SEL1L3

811

Q68CR1
PYLCGKNGGGAFLIP

SLC6A1

71

P30531
RPELGAGTPIFYGIF

SEMA4F

316

O95754
GSLGPREYFIPGTRL

MIA3

1846

Q5JRA6
LGLILGPPVGGFLYQ

SLC18B1

176

Q6NT16
GPSGGQPRALDSGYD

AATK

926

Q6ZMQ8
PYGGRGSSFSLGLPF

NFATC4

791

Q14934
FYGRLRGDAAAGPGP

NXN

56

Q6DKJ4
GRTPQFGQLVYPAGG

TAF1C

221

Q15572
IYLIGGDLGPFNPGL

GINS2

26

Q9Y248
PGEAYLRQPGFASGL

FOXE3

301

Q13461
LSGGYPGSAPLQRNF

PRC1

556

O43663
LPYRAEVGPAGSQFG

RHBDF1

711

Q96CC6
QAEGGGPDGPLYKVS

RAP1GAP

321

P47736
AVAAPYGGPSGRGQV

ITGA2B

406

P08514
YGGPSGRGQVLVFLG

ITGA2B

411

P08514
QGDPGYPLGRFGEAI

ITGAL

511

P20701
GGRDLPAEQPGSFLY

SEMA4C

591

Q9C0C4
EELSRYRGGPGDPGL

CYB5D2

41

Q8WUJ1
YRGGPGDPGLYLALL

CYB5D2

46

Q8WUJ1
PGFLYGSATPEDRGL

SGCA

86

Q16586
VGEGLYQGVPRAEPG

SLC45A3

296

Q96JT2
VKLEGPGPALGYFRG

SOX30

166

O94993
YGPLPEGTVGLILGR

ERVK-9

691

P63128
LGYGAGAVRPAVPTG

SRRT

806

Q9BXP5
GLNYTPLLYSRGNPG

ARID5B

671

Q14865
YPLVKAVQEGPGGGR

CFAP210

491

Q0VFZ6
LLVYGPREGGRGAPD

CHPF2

526

Q9P2E5
GTPGPRRLLKGFYGS

CHRD

591

Q9H2X0
EILANRPYTDGPGGS

PITPNM1

41

O00562
SYIRAVFGSRGPGLP

RINL

321

Q6ZS11
GDSLGARPGLPYGLS

ZNF513

71

Q8N8E2
GAFPDRGVLGGVLFP

SH3BGR

46

P55822
PEGGGGSARPRYSLL

STK35

191

Q8TDR2
YNNPLGTGGRLAIGF

USP19

536

O94966
RDGRTGELGYLNPGV

GGCX

416

P38435
ILGPPGSVYEGGVFF

UBE2E2

91

Q96LR5
YRPPGGSGIGRSSEL

SRRM5

196

B3KS81
GAAGLYEPGAALGPL

SHANK3

866

Q9BYB0
SPFLGYAGGPELAQG

SLC27A3

496

Q5K4L6
ALGPTGRGVVEYFGL

SPTLC2

351

O15270
GGTDPVYNIGALLRG

SYBU

631

Q9NX95
NRGLKLTSTGPGPGY

STPG1

216

Q5TH74
PGPYRQADRYGFIGG

TBC1D10C

31

Q8IV04
PLPILLVTGGGYAGY

PISD

66

Q9UG56
TILGPPGSVYEGGVF

UBE2E3

96

Q969T4
GSHYRGLVPGEPAGR

TSPO

26

B1AH88
ATGPSGLRVLPQGYG

SLC12A9

151

Q9BXP2
LQPVPLGGRGGQYDG

ZNF609

186

O15014
GSGVVGIVDYGPRPN

STAB2

2266

Q8WWQ8
LGAGYRLGPAQPGAD

TBX6

11

O95947
PRPGLLGSIGEGRYF

REL

346

Q04864
VYLGSFRGVQKPAGP

PRAG1

131

Q86YV5
QETYGHLGALGFPGP

ZNF688

56

P0C7X2
AFKGLPGIDFRGGPA

ZNF536

841

O15090
RRLGGIGHTPAGPYD

TIGD5

626

Q53EQ6
LFPDYRIGLGEGAGP

ZNF629

691

Q9UEG4
RGGDPYQLLQGDGTA

ZMYND15

431

Q9H091
YPGKNGRLGDFFGDP

GTF2H3

71

Q13889
GGSLELPGRDQPYSG

TYRO3

816

Q06418
LPGRDQPYSGAGDGS

TYRO3

821

Q06418
GVPFGLYTPASRGTG

ZNRF1

66

Q8ND25
DGEAPRGISSGYPFL

ZNF662

41

Q6ZS27
RGILLFGPPGTGKSY

VPS4A

161

Q9UN37
AGGAYGPGTPELLLE

LTB

166

Q06643
SSQRFGVPLGYGGPH

GLDC

316

P23378
RPPERVGAGGLDGYS

MYBPC3

891

Q14896