Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	voltage-gated chloride channel activity	CLCNKA CLCNKB	1.63e-04	11	35	2	GO:0005247
GeneOntologyMolecularFunction	voltage-gated monoatomic anion channel activity	CLCNKA CLCNKB	3.99e-04	17	35	2	GO:0008308
GeneOntologyMolecularFunction	D-glucose transmembrane transporter activity	SLC2A3 SLC2A4	8.73e-04	25	35	2	GO:0055056
GeneOntologyMolecularFunction	hexose transmembrane transporter activity	SLC2A3 SLC2A4	8.73e-04	25	35	2	GO:0015149
GeneOntologyMolecularFunction	monosaccharide transmembrane transporter activity	SLC2A3 SLC2A4	1.02e-03	27	35	2	GO:0015145
GeneOntologyMolecularFunction	sugar transmembrane transporter activity	SLC2A3 SLC2A4	1.18e-03	29	35	2	GO:0051119
GeneOntologyMolecularFunction	ubiquitin conjugating enzyme activity	UBE2O UBE2G2	1.91e-03	37	35	2	GO:0061631
GeneOntologyMolecularFunction	carbohydrate transmembrane transporter activity	SLC2A3 SLC2A4	2.46e-03	42	35	2	GO:0015144
GeneOntologyMolecularFunction	ubiquitin-like protein conjugating enzyme activity	UBE2O UBE2G2	2.58e-03	43	35	2	GO:0061650
GeneOntologyBiologicalProcess	D-glucose import	ACE SLC2A3 SLC2A4 C2CD5	2.33e-05	102	34	4	GO:0046323
GeneOntologyBiologicalProcess	dehydroascorbic acid transport	SLC2A3 SLC2A4	9.43e-05	9	34	2	GO:0070837
GeneOntologyBiologicalProcess	negative regulation of retrograde protein transport, ER to cytosol	UBAC2 UBE2G2	9.43e-05	9	34	2	GO:1904153
GeneOntologyBiologicalProcess	D-glucose transmembrane transport	ACE SLC2A3 SLC2A4 C2CD5	9.98e-05	148	34	4	GO:1904659
GeneOntologyBiologicalProcess	hexose transmembrane transport	ACE SLC2A3 SLC2A4 C2CD5	1.08e-04	151	34	4	GO:0008645
GeneOntologyBiologicalProcess	monosaccharide transmembrane transport	ACE SLC2A3 SLC2A4 C2CD5	1.16e-04	154	34	4	GO:0015749
GeneOntologyBiologicalProcess	transepithelial chloride transport	CLCNKA CLCNKB	1.18e-04	10	34	2	GO:0030321
GeneOntologyBiologicalProcess	negative regulation of protein exit from endoplasmic reticulum	UBAC2 UBE2G2	1.18e-04	10	34	2	GO:0070862
GeneOntologyBiologicalProcess	carbohydrate transmembrane transport	ACE SLC2A3 SLC2A4 C2CD5	1.63e-04	168	34	4	GO:0034219
GeneOntologyBiologicalProcess	regulation of retrograde protein transport, ER to cytosol	UBAC2 UBE2G2	2.37e-04	14	34	2	GO:1904152
GeneOntologyBiologicalProcess	carbohydrate transport	ACE SLC2A3 SLC2A4 C2CD5	2.40e-04	186	34	4	GO:0008643
HumanPheno	Hypokalemic hypochloremic metabolic alkalosis	CLCNKA CLCNKB	1.27e-05	3	11	2	HP:0004909
HumanPheno	Hypochloremic metabolic alkalosis	CLCNKA CLCNKB	2.54e-05	4	11	2	HP:0005977
HumanPheno	Abnormal urine chloride concentration	CLCNKA CLCNKB	4.22e-05	5	11	2	HP:0012600
HumanPheno	Hyperchloriduria	CLCNKA CLCNKB	4.22e-05	5	11	2	HP:0002914
HumanPheno	Hyperprostaglandinuria	CLCNKA CLCNKB	6.33e-05	6	11	2	HP:0003527
HumanPheno	Abnormal circulating prostaglandin circulation	CLCNKA CLCNKB	6.33e-05	6	11	2	HP:0011023
HumanPheno	Hypochloremia	CLCNKA CLCNKB	8.85e-05	7	11	2	HP:0003113
HumanPheno	Impaired renal concentrating ability	CLCNKA CLCNKB	8.85e-05	7	11	2	HP:0004727
HumanPheno	Hyperactive renin-angiotensin system	CLCNKA CLCNKB	1.18e-04	8	11	2	HP:0000841
HumanPheno	Abnormal circulating unsaturated fatty acid concentration	CLCNKA CLCNKB	1.18e-04	8	11	2	HP:0011022
HumanPheno	Abnormal circulating eicosanoid concentration	CLCNKA CLCNKB	1.18e-04	8	11	2	HP:0030361
HumanPheno	Impaired renal function	CLCNKA CLCNKB	1.51e-04	9	11	2	HP:0000087
HumanPheno	Hypokalemic metabolic alkalosis	CLCNKA CLCNKB	1.51e-04	9	11	2	HP:0001960
HumanPheno	Increased urinary potassium	CLCNKA CLCNKB	1.51e-04	9	11	2	HP:0003081
HumanPheno	Hypernatriuria	CLCNKA CLCNKB	1.89e-04	10	11	2	HP:0012605
HumanPheno	Hypokalemic alkalosis	CLCNKA CLCNKB	2.77e-04	12	11	2	HP:0001949
HumanPheno	Fetal polyuria	CLCNKA CLCNKB	2.77e-04	12	11	2	HP:0001563
HumanPheno	Abnormal urine output	CLCNKA ACE CLCNKB	3.63e-04	69	11	3	HP:0012590
HumanPheno	Abnormality of renal excretion	CLCNKA ACE CLCNKB	4.65e-04	75	11	3	HP:0011036
HumanPheno	Digenic inheritance	CLCNKA CLCNKB	5.00e-04	16	11	2	HP:0010984
HumanPheno	Delayed ability to stand	CLCNKA CLCNKB	5.67e-04	17	11	2	HP:0025335
HumanPheno	Severe failure to thrive	CLCNKA CLCNKB	5.67e-04	17	11	2	HP:0001525
HumanPheno	Abnormal drinking behavior	CLCNKB BBS9 SLC2A3	5.83e-04	81	11	3	HP:0030082
HumanPheno	Metabolic alkalosis	CLCNKA CLCNKB	6.37e-04	18	11	2	HP:0200114
HumanPheno	Abnormal urine sodium concentration	CLCNKA CLCNKB	6.37e-04	18	11	2	HP:0012603
HumanPheno	Abnormal urine potassium concentration	CLCNKA CLCNKB	6.37e-04	18	11	2	HP:0012598
HumanPheno	Clumsiness	CLCNKA CLCNKB SLC2A3	6.95e-04	86	11	3	HP:0002312
HumanPheno	Increased circulating renin concentration	CLCNKA CLCNKB	7.11e-04	19	11	2	HP:0000848
MousePheno	hypotension	ADRA1A ACE CLCNKB	8.02e-06	28	20	3	MP:0001596
MousePheno	decreased urine osmolality	CLCNKA ACE CLCNKB	5.93e-05	54	20	3	MP:0002988
MousePheno	abnormal urine osmolality	CLCNKA ACE CLCNKB	1.03e-04	65	20	3	MP:0002987
MousePheno	abnormal sinus arrhythmia	PCYOX1L ADRA1A TMTC3	1.78e-04	78	20	3	MP:0004122
MousePheno	abnormal kidney arterial blood vessel morphology	ACE CLCNKB	2.31e-04	16	20	2	MP:0011309
MousePheno	polyuria	CLCNKA ACE CLCNKB	2.63e-04	89	20	3	MP:0001762
MousePheno	increased urine potassium level	ACE CLCNKB	2.93e-04	18	20	2	MP:0005619
MousePheno	abnormal systemic arterial blood pressure	ADRA1A ACE CLCNKB SLC2A4	3.58e-04	245	20	4	MP:0000230
MousePheno	decreased adipocyte glucose uptake	SLC2A4 C2CD5	3.64e-04	20	20	2	MP:0030017
MousePheno	decreased systemic arterial blood pressure	ADRA1A ACE CLCNKB	4.16e-04	104	20	3	MP:0002843
MousePheno	increased circulating renin level	ACE CLCNKB	4.83e-04	23	20	2	MP:0003352
MousePheno	decreased heart weight	PCYOX1L ACE CLCNKB	6.02e-04	118	20	3	MP:0002834
MousePheno	abnormal circulating renin level	ACE CLCNKB	7.71e-04	29	20	2	MP:0003349
Domain	Cl_channel-K	CLCNKA CLCNKB	2.67e-06	2	31	2	IPR002250
Domain	Cl-channel_core	CLCNKA CLCNKB	9.53e-05	9	31	2	IPR014743
Domain	-	CLCNKA CLCNKB	9.53e-05	9	31	2	1.10.3080.10
Domain	Voltage_CLC	CLCNKA CLCNKB	9.53e-05	9	31	2	PF00654
Domain	Cl-channel_volt-gated	CLCNKA CLCNKB	9.53e-05	9	31	2	IPR001807
Domain	Sugar/inositol_transpt	SLC2A3 SLC2A4	2.40e-04	14	31	2	IPR003663
Domain	CBS	CLCNKA CLCNKB	3.15e-04	16	31	2	SM00116
Domain	SUGAR_TRANSPORT_2	SLC2A3 SLC2A4	3.57e-04	17	31	2	PS00217
Domain	CBS_dom	CLCNKA CLCNKB	4.97e-04	20	31	2	IPR000644
Domain	CBS	CLCNKA CLCNKB	4.97e-04	20	31	2	PF00571
Domain	CBS	CLCNKA CLCNKB	4.97e-04	20	31	2	PS51371
Domain	SUGAR_TRANSPORT_1	SLC2A3 SLC2A4	7.19e-04	24	31	2	PS00216
Domain	Sugar_transporter_CS	SLC2A3 SLC2A4	1.28e-03	32	31	2	IPR005829
Domain	Sugar_tr	SLC2A3 SLC2A4	1.62e-03	36	31	2	PF00083
Domain	MFS_sugar_transport-like	SLC2A3 SLC2A4	1.62e-03	36	31	2	IPR005828
Domain	UQ_con	UBE2O UBE2G2	1.90e-03	39	31	2	PF00179
Domain	UBIQUITIN_CONJUGAT_1	UBE2O UBE2G2	2.00e-03	40	31	2	PS00183
Domain	UBIQUITIN_CONJUGAT_2	UBE2O UBE2G2	2.10e-03	41	31	2	PS50127
Domain	UBQ-conjugat_E2	UBE2O UBE2G2	2.10e-03	41	31	2	IPR000608
Domain	-	UBE2O UBE2G2	3.23e-03	51	31	2	3.10.110.10
Domain	UBQ-conjugating_enzyme/RWD	UBE2O UBE2G2	3.49e-03	53	31	2	IPR016135
Domain	C1-set	MICA IGHG4	3.62e-03	54	31	2	PF07654
Domain	IGc1	MICA IGHG4	3.88e-03	56	31	2	SM00407
Domain	Ig_C1-set	MICA IGHG4	4.16e-03	58	31	2	IPR003597
Domain	MFS	SLC2A3 SLC2A4	1.38e-02	108	31	2	PS50850
Pubmed	Cloning, tissue distribution, and intrarenal localization of ClC chloride channels in human kidney.	CLCNKA CLCNKB	9.84e-07	2	35	2	8544406
Pubmed	The ClC-K2 Chloride Channel Is Critical for Salt Handling in the Distal Nephron.	CLCNKA CLCNKB	9.84e-07	2	35	2	27335120
Pubmed	Cloning and characterization of Ehox, a novel homeobox gene essential for embryonic stem cell differentiation.	RHOXF2B RHOXF2	9.84e-07	2	35	2	12087094
Pubmed	Assignment of the genes encoding the human chloride channels, CLCNKA and CLCNKB, to 1p36 and of CLCN3 to 4q32-q33 by in situ hybridization.	CLCNKA CLCNKB	9.84e-07	2	35	2	8812470
Pubmed	Immunohistochemical Evaluation of GLUT-3 and GLUT-4 in Oral Epithelial Dysplasia and Oral Squamous Cell Carcinoma.	SLC2A3 SLC2A4	9.84e-07	2	35	2	30049187
Pubmed	Associations between CLCNKA_B tag SNPs with essential hypertension and interactions between genetic and environmental factors in an island population in China.	CLCNKA CLCNKB	9.84e-07	2	35	2	25919862
Pubmed	Targeting kidney CLC-K channels: pharmacological profile in a human cell line versus Xenopus oocytes.	CLCNKA CLCNKB	9.84e-07	2	35	2	24863058
Pubmed	Overt nephrogenic diabetes insipidus in mice lacking the CLC-K1 chloride channel.	CLCNKA CLCNKB	9.84e-07	2	35	2	9916798
Pubmed	Kidney kinetics and chloride ion pumps.	CLCNKA CLCNKB	9.84e-07	2	35	2	9916791
Pubmed	Expanding Genotype-Phenotype Correlation of CLCNKA and CLCNKB Variants Linked to Hearing Loss.	CLCNKA CLCNKB	9.84e-07	2	35	2	38069401
Pubmed	A regulatory calcium-binding site at the subunit interface of CLC-K kidney chloride channels.	CLCNKA CLCNKB	9.84e-07	2	35	2	20805576
Pubmed	Mammalian Glucose Transporter Activity Is Dependent upon Anionic and Conical Phospholipids.	SLC2A3 SLC2A4	9.84e-07	2	35	2	27302065
Pubmed	Rhox homeobox gene cluster: recent duplication of three family members.	RHOXF2B RHOXF2	9.84e-07	2	35	2	16496311
Pubmed	Apolipoprotein B and angiotensin-converting enzyme polymorphisms and aerobic interval training: randomized controlled trial in coronary artery disease patients.	APOB ACE	9.84e-07	2	35	2	29846435
Pubmed	Salt wasting and deafness resulting from mutations in two chloride channels.	CLCNKA CLCNKB	9.84e-07	2	35	2	15044642
Pubmed	Identification of a tandem duplicated array in the Rhox alpha locus on mouse chromosome X.	RHOXF2B RHOXF2	9.84e-07	2	35	2	16465597
Pubmed	Cloning and characterization of the 5'-flanking region of the Ehox gene.	RHOXF2B RHOXF2	9.84e-07	2	35	2	16414020
Pubmed	Two highly homologous members of the ClC chloride channel family in both rat and human kidney.	CLCNKA CLCNKB	9.84e-07	2	35	2	8041726
Pubmed	A cytoplasmic domain mutation in ClC-Kb affects long-distance communication across the membrane.	CLCNKA CLCNKB	9.84e-07	2	35	2	18648499
Pubmed	Cl(-) channels in basolateral TAL membranes XV. Molecular heterogeneity between cortical and medullary channels.	CLCNKA CLCNKB	9.84e-07	2	35	2	11014860
Pubmed	A microarray minisequencing system for pharmacogenetic profiling of antihypertensive drug response.	APOB ADRA1A ACE	2.11e-06	25	35	3	12544508
Pubmed	Human CLC-K Channels Require Palmitoylation of Their Accessory Subunit Barttin to Be Functional.	CLCNKA CLCNKB	2.95e-06	3	35	2	26013830
Pubmed	Barttin increases surface expression and changes current properties of ClC-K channels.	CLCNKA CLCNKB	2.95e-06	3	35	2	12111250
Pubmed	Common genetic variants and haplotypes in renal CLCNKA gene are associated to salt-sensitive hypertension.	CLCNKA CLCNKB	2.95e-06	3	35	2	17510212
Pubmed	The rhox homeobox gene family shows sexually dimorphic and dynamic expression during mouse embryonic gonad development.	RHOXF2B RHOXF2	2.95e-06	3	35	2	18562707
Pubmed	Sustained hypoglycemia affects glucose transporter expression of human blood leukocytes.	SLC2A3 SLC2A4	2.95e-06	3	35	2	12064911
Pubmed	C2 domain-containing phosphoprotein CDP138 regulates GLUT4 insertion into the plasma membrane.	SLC2A4 C2CD5	2.95e-06	3	35	2	21907143
Pubmed	Population genetic analysis of the genes APOE, APOB(3'VNTR) and ACE in some black and Amerindian communities from Colombia.	APOB ACE	2.95e-06	3	35	2	11359065
Pubmed	The RHOX5 homeodomain protein mediates transcriptional repression of the netrin-1 receptor gene Unc5c.	RHOXF2B RHOXF2	2.95e-06	3	35	2	18077458
Pubmed	IGF-I increases the recruitment of GLUT4 and GLUT3 glucose transporters on cell surface in hyperthyroidism.	SLC2A3 SLC2A4	2.95e-06	3	35	2	18299470
Pubmed	Triiodothyronine acutely stimulates glucose transport into L6 muscle cells without increasing surface GLUT4, GLUT1, or GLUT3.	SLC2A3 SLC2A4	2.95e-06	3	35	2	22663547
Pubmed	Expression of glucose transporters in epithelial ovarian carcinoma: correlation with clinical characteristics and tumor angiogenesis.	SLC2A3 SLC2A4	2.95e-06	3	35	2	17611657
Pubmed	Five polymorphisms in gene candidates for cardiovascular disease in Afro-Brazilian individuals.	APOB ACE	2.95e-06	3	35	2	15543563
Pubmed	The role of angiotensin-converting enzyme and apolipoprotein-E gene polymorphisms on lipid compositions in newborn infants with intrauterine growth restriction.	APOB ACE	2.95e-06	3	35	2	15223114
Pubmed	Barttin is a Cl- channel beta-subunit crucial for renal Cl- reabsorption and inner ear K+ secretion.	CLCNKA CLCNKB	2.95e-06	3	35	2	11734858
Pubmed	Barttin modulates trafficking and function of ClC-K channels.	CLCNKA CLCNKB	2.95e-06	3	35	2	16849430
Pubmed	Mechanisms of Disease: the kidney-specific chloride channels ClCKA and ClCKB, the Barttin subunit, and their clinical relevance.	CLCNKA CLCNKB	2.95e-06	3	35	2	18094726
Pubmed	Transcriptional regulation of the CLC-K1 promoter by myc-associated zinc finger protein and kidney-enriched Krüppel-like factor, a novel zinc finger repressor.	CLCNKA CLCNKB	2.95e-06	3	35	2	10982849
Pubmed	Cytoprotective effects of hesperetin and hesperidin against amyloid β-induced impairment of glucose transport through downregulation of neuronal autophagy.	SLC2A3 SLC2A4	5.90e-06	4	35	2	22383310
Pubmed	Haplotype diversity in four genes (CLCNKA, CLCNKB, BSND, NEDD4L) involved in renal salt reabsorption.	CLCNKA CLCNKB	5.90e-06	4	35	2	17652939
Pubmed	Changes in Expression of Follicular Glucose Transporters May Be Involved in Ovarian Function Impairment during Diabetic Hyperglycemia.	SLC2A3 SLC2A4	5.90e-06	4	35	2	31882430
Pubmed	Structural analysis of the GLUT1 facilitative glucose transporter (review).	SLC2A3 SLC2A4	5.90e-06	4	35	2	11681785
Pubmed	Kinetic analysis of the liver-type (GLUT2) and brain-type (GLUT3) glucose transporters in Xenopus oocytes: substrate specificities and effects of transport inhibitors.	SLC2A3 SLC2A4	5.90e-06	4	35	2	8457197
Pubmed	Placental glucose transfer and fetal growth.	SLC2A3 SLC2A4	5.90e-06	4	35	2	12583599
Pubmed	In vitro analysis of the glucose-transport system in GLUT4-null skeletal muscle.	SLC2A3 SLC2A4	5.90e-06	4	35	2	10455018
Pubmed	Cloning and characterization of the major insulin-responsive glucose transporter expressed in human skeletal muscle and other insulin-responsive tissues.	SLC2A3 SLC2A4	5.90e-06	4	35	2	2656669
Pubmed	α1A-Adrenergic receptor prevents cardiac ischemic damage through PKCδ/GLUT1/4-mediated glucose uptake.	ADRA1A SLC2A4	5.90e-06	4	35	2	26832303
Pubmed	Prenatal Exposure to Sodium Arsenite Alters Placental Glucose 1, 3, and 4 Transporters in Balb/c Mice.	SLC2A3 SLC2A4	5.90e-06	4	35	2	26339590
Pubmed	Immunohistochemical localization and quantification of glucose transporters in the mouse brain.	SLC2A3 SLC2A4	5.90e-06	4	35	2	11955709
Pubmed	Rhox: a new homeobox gene cluster.	RHOXF2B RHOXF2	5.90e-06	4	35	2	15707895
Pubmed	Leptin at gender-specific concentrations does not affect glucose transport, expression of glucose transporters and leptin receptors in human lymphocytes.	SLC2A3 SLC2A4	9.82e-06	5	35	2	25306890
Pubmed	Genetic associations with mountain sickness in Han and Tibetan residents at the Qinghai-Tibetan Plateau.	APOB ACE	9.82e-06	5	35	2	20570668
Pubmed	Developmental expression and cellular localization of glucose transporter molecules during mouse preimplantation development.	SLC2A3 SLC2A4	9.82e-06	5	35	2	1638987
Pubmed	The glucose transporter family: structure, function and tissue-specific expression.	SLC2A3 SLC2A4	9.82e-06	5	35	2	8240230
Pubmed	Prenatal expression of the GLUT4 glucose transporter in the mouse.	SLC2A3 SLC2A4	9.82e-06	5	35	2	10965149
Pubmed	Expression of a novel homeobox gene Ehox in trophoblast stem cells and pharyngeal pouch endoderm.	RHOXF2B RHOXF2	9.82e-06	5	35	2	14648851
Pubmed	Differential screening of a PCR-generated mouse embryo cDNA library: glucose transporters are differentially expressed in early postimplantation mouse embryos.	SLC2A3 SLC2A4	9.82e-06	5	35	2	1289053
Pubmed	Glucose uptake mediated by glucose transporter 1 is essential for early tooth morphogenesis and size determination of murine molars.	SLC2A3 SLC2A4	1.47e-05	6	35	2	22226978
Pubmed	Impairment in renal medulla development underlies salt wasting in Clc-k2 channel deficiency.	CLCNKA CLCNKB	2.06e-05	7	35	2	34499620
Pubmed	[Population study of the Udmurt population: analysis of ten polymorphic DNA loci of the nuclear genome].	APOB ACE	2.06e-05	7	35	2	17633563
Pubmed	Intrarenal and cellular localization of CLC-K2 protein in the mouse kidney.	CLCNKA CLCNKB	2.06e-05	7	35	2	11423561
Pubmed	Candidate gene polymorphism in cardiovascular disease: the BIP cohort.	APOB ACE	2.74e-05	8	35	2	16544732
Pubmed	Impact of genetic polymorphisms on platelet function and aspirin resistance.	APOB ACE	3.53e-05	9	35	2	19923980
Pubmed	Expression of hexokinases and glucose transporters in treated and untreated oesophageal adenocarcinoma.	SLC2A3 SLC2A4	3.53e-05	9	35	2	19554504
Pubmed	Gene-load score of the renin-angiotensin-aldosterone system is associated with coronary heart disease in familial hypercholesterolaemia.	ADRA1A ACE	3.53e-05	9	35	2	18413308
Pubmed	Changing expression of chloride channels during preimplantation mouse development.	CLCNKA CLCNKB	3.53e-05	9	35	2	23115349
Pubmed	A prospective case-control study analyzes 12 thrombophilic gene mutations in Turkish couples with recurrent pregnancy loss.	APOB ACE	4.40e-05	10	35	2	19906129
Pubmed	Vascular at-risk genotypes and disease severity in Lebanese sickle cell disease patients.	APOB ACE	4.40e-05	10	35	2	20425806
Pubmed	Prevalence of prothrombotic polymorphisms in Greece.	APOB ACE	4.40e-05	10	35	2	19072566
Pubmed	A comprehensive analysis of 12 thrombophilic mutations and related parameters in patients with inflammatory bowel disease: data from Turkey.	APOB ACE	4.40e-05	10	35	2	17111197
Pubmed	Cell-cell adhesion defects in Mrj mutant trophoblast cells are associated with failure to pattern the chorion during early placental development.	RHOXF2B RHOXF2	4.40e-05	10	35	2	21972064
Pubmed	Neural Deletion of Glucose Transporter Isoform 3 Creates Distinct Postnatal and Adult Neurobehavioral Phenotypes.	SLC2A3 SLC2A4	5.38e-05	11	35	2	30232223
Pubmed	Nutrigenetics: links between genetic background and response to Mediterranean-type diets.	APOB ACE	5.38e-05	11	35	2	19689828
Pubmed	Frequencies of polymorphisms in cytokines, neurotransmitters and adrenergic receptors in patients with complex regional pain syndrome type I after distal radial fracture.	ADRA1A ACE	5.38e-05	11	35	2	20173430
Pubmed	A major X-linked locus affects kidney function in mice.	RHOXF2B RHOXF2	6.45e-05	12	35	2	23011808
Pubmed	Deletion of the Syncytin A receptor Ly6e impairs syncytiotrophoblast fusion and placental morphogenesis causing embryonic lethality in mice.	RHOXF2B RHOXF2	6.45e-05	12	35	2	29500366
Pubmed	Genetic influences on lipid metabolism trait variability within the Stanislas Cohort.	APOB ACE	6.45e-05	12	35	2	11714857
Pubmed	Intestinal maturation in mice lacking CCAAT/enhancer-binding protein alpha (C/EPBalpha).	APOB SLC2A4	7.62e-05	13	35	2	9494081
Pubmed	Genetic influences on blood pressure within the Stanislas Cohort.	APOB ACE	7.62e-05	13	35	2	15076187
Pubmed	The environmental and genetic evidence for the association of hyperlipidemia and hypertension.	APOB ACE	7.62e-05	13	35	2	19155782
Pubmed	Genetic cardiovascular risk factors and age-related macular degeneration.	APOB ACE	7.62e-05	13	35	2	19860767
Pubmed	Candidate gene polymorphisms in cardiovascular disease: a comparative study of frequencies between a French and an Italian population.	APOB ACE	1.02e-04	15	35	2	11341749
Pubmed	Molecular variation at functional genes and the history of human populations--data on candidate genes for cardiovascular risk in the Mediterranean.	APOB ACE	1.02e-04	15	35	2	14746139
Pubmed	Association of sixty-one non-synonymous polymorphisms in forty-one hypertension candidate genes with blood pressure variation and hypertension.	APOB CLCNKB	1.17e-04	16	35	2	17137217
Pubmed	The thiazide-sensitive Na(+)-Cl(-) cotransporter gene, C1784T, and adrenergic receptor-beta3 gene, T727C, may be gene polymorphisms susceptible to the antihypertensive effect of thiazide diuretics.	ADRA1A ACE	1.17e-04	16	35	2	15824464
Pubmed	Lp(a) and risk of recurrent cardiac events in obese postinfarction patients.	APOB ACE	1.33e-04	17	35	2	18927546
Pubmed	Glucose transporter gene expression in early mouse embryos.	SLC2A3 SLC2A4	1.49e-04	18	35	2	1765007
Pubmed	ARHGEF18/p114RhoGEF Coordinates PKA/CREB Signaling and Actomyosin Remodeling to Promote Trophoblast Cell-Cell Fusion During Placenta Morphogenesis.	RHOXF2B RHOXF2	1.49e-04	18	35	2	33842485
Pubmed	Identification of ERAD components essential for dislocation of the null Hong Kong variant of α-1-antitrypsin (NHK).	UBAC2 UBE2G2	1.66e-04	19	35	2	25660456
Pubmed	Can we predict top-level sports performance in power vs endurance events? A genetic approach.	APOB ACE	1.85e-04	20	35	2	20459474
Pubmed	AMPK Interactome Reveals New Function in Non-homologous End Joining DNA Repair.	PPP1R3D UBE2O TMTC3	2.48e-04	121	35	3	31900314
Pubmed	DNA methylation regulates long-range gene silencing of an X-linked homeobox gene cluster in a lineage-specific manner.	RHOXF2B RHOXF2	2.68e-04	24	35	2	17182866
Pubmed	Genetic variation in healthy oldest-old.	APOB TRDMT1	2.68e-04	24	35	2	19680556
Pubmed	Phosphorylation of Parkin at Serine65 is essential for activation: elaboration of a Miro1 substrate-based assay of Parkin E3 ligase activity.	UBE2O UBE2G2	2.68e-04	24	35	2	24647965
Pubmed	TMUB1 is an endoplasmic reticulum-resident escortase that promotes the p97-mediated extraction of membrane proteins for degradation.	UBAC2 RNF170	3.15e-04	26	35	2	35961308
Pubmed	Maternal DNA Methylation Regulates Early Trophoblast Development.	RHOXF2B RHOXF2	3.66e-04	28	35	2	26812015
Pubmed	Specification of jaw identity by the Hand2 transcription factor.	RHOXF2B RHOXF2	3.66e-04	28	35	2	27329940
Pubmed	An evaluation of the assembly of an approximately 15-Mb region on human chromosome 13q32-q33 linked to bipolar disorder and schizophrenia.	UBAC2 BIVM	3.93e-04	29	35	2	11991713
Pubmed	Identification of translationally controlled tumor protein in promotion of DNA homologous recombination repair in cancer cells by affinity proteomics.	UBAC2 UBE2O UBE2G2	4.21e-04	145	35	3	28846114
Pubmed	Population based allele frequencies of disease associated polymorphisms in the Personalized Medicine Research Project.	APOB ACE	8.66e-04	43	35	2	20565774
Cytoband	1p36	CLCNKA CLCNKB	5.97e-04	47	35	2	1p36
Cytoband	Xq24	RHOXF2B RHOXF2	1.10e-03	64	35	2	Xq24
Cytoband	Ensembl 112 genes in cytogenetic band chrXq24	RHOXF2B RHOXF2	1.76e-03	81	35	2	chrXq24
GeneFamily	Chloride voltage-gated channels	CLCNKA CLCNKB	8.89e-05	10	26	2	302
Coexpression	GSE21927_SPLENIC_VS_TUMOR_MONOCYTES_FROM_C26GM_TUMOROUS_MICE_BALBC_UP	CFAP47 SNED1 C2orf81 ANKRD40 SAMD11	4.93e-06	194	34	5	M7587
ToppCell	TCGA-Head_and_Esophagus-Solid_Tissue_Normal-Head_and_Neck-Head_and_Neck_normal_tissue-2\|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9	ADRA1A UGT2B28 CLCNKB SLC2A4	7.96e-06	163	35	4	2dfd11f5803822ba01b92adf4395a3b3adda68f5
ToppCell	PCW_07-8.5-Epithelial-Epithelial_ciliated\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CFAP47 CLCNKB DNAH7 ENTPD3	8.36e-06	165	35	4	82530f96aaefe28a13bad0474bbad043f127a86c
ToppCell	PCW_07-8.5-Epithelial-Epithelial_ciliated-epi_ciliated_(14)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CFAP47 CLCNKB DNAH7 ENTPD3	8.36e-06	165	35	4	0c714e852f912b5749de4cb0895406673979b2e6
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP47 SNED1 CLCNKA DNAH7	9.18e-06	169	35	4	fba841664939c771881ba97f14ef1df6635c04ff
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.4\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CLCNKA CLCNKB C2orf81 DNAH7	1.43e-05	189	35	4	cd4746ea6ae48a7dd14a2960d38d9445a738cf2c
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TMTC3 CLCNKA CLCNKB RNF170	1.58e-05	194	35	4	ea5b7727ffef6cb454c501979a51bc1d4108d0e4
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MROH7 DSCAM CLCNKA CLCNKB	1.65e-05	196	35	4	50aaca81b593ff71790bb75403b2e4c3ab03a6d2
ToppCell	Skin-Tubules\|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.	CFAP47 CLCNKA CLCNKB DNAH7	1.65e-05	196	35	4	12e21cc310a261407b46e034108e8c93ea16e045
ToppCell	facs-Marrow-KLS-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBE2O SAMD11 SLC2A4	2.56e-04	158	35	3	0edd9b005875f9a4f5446f5d5161f8ba63860793
ToppCell	facs-Marrow-KLS-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBE2O SAMD11 SLC2A4	2.56e-04	158	35	3	9fd77ebdd1babf1c85a85d38d9a15858ab08bc84
ToppCell	facs-Lung-EPCAM-3m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R3D SLC2A3 ENTPD3	2.66e-04	160	35	3	b73f07a0088936fbc3656a05710a67f38b4ae551
ToppCell	facs-Lung-EPCAM-3m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R3D SLC2A3 ENTPD3	2.66e-04	160	35	3	b88876a58fea2066468e74dcc439c8561130a910
ToppCell	facs-Marrow-T-cells-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBE2O SAMD11 SLC2A4	2.71e-04	161	35	3	1ce40a6d0f0b9870e7ddb3d607668adcbd3dd1d3
ToppCell	facs-Marrow-T-cells-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBE2O SAMD11 SLC2A4	2.71e-04	161	35	3	79a4a81963c92ade5b6910816a440dc3c233ead2
ToppCell	3'-Distal_airway-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DSCAM CLCNKA CLCNKB	2.76e-04	162	35	3	9522af31f6b2f3cb81b6b84bd08353eea504d1d6
ToppCell	3'-Distal_airway-Epithelial-Neuro-endocrine/ionocytic-ionocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DSCAM CLCNKA CLCNKB	2.76e-04	162	35	3	9a18286e361e1dd18e6f943ce27db58b199fb6e4
ToppCell	3'-Distal_airway-Epithelial-Neuro-endocrine/ionocytic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DSCAM CLCNKA CLCNKB	2.76e-04	162	35	3	40265af9b36fd144a8577b8dacccd4fc0888a593
ToppCell	3'-Distal_airway-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DSCAM CLCNKA CLCNKB	2.76e-04	162	35	3	3395e4dffdb9304d157c325e1fc0f12b433c7bd3
ToppCell	TCGA-Uterus-Primary_Tumor-Uterine_Carcinoma-Uterine_Carcinosarcoma-3\|TCGA-Uterus / Sample_Type by Project: Shred V9	TMTC3 ACE ENTPD3	2.81e-04	163	35	3	d64dd39b077105c73e570ccef70f0e74a2c586ac
ToppCell	facs-Marrow-B-cells-24m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBE2O SAMD11 SLC2A4	2.86e-04	164	35	3	18eeda51e69722992c3a7f699be293535a90868b
ToppCell	droplet-Spleen-nan-21m-Lymphocytic-NK_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SNED1 UBE2G2 DSCAM	3.01e-04	167	35	3	92ddabbe55315856d8ea6f8db1560b6d97636bac
ToppCell	facs-Marrow-B-cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBE2O SAMD11 SLC2A4	3.07e-04	168	35	3	17fb9426eeea407b26fb895b8397faca95b7552d
ToppCell	facs-Marrow-B-cells-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBE2O SAMD11 SLC2A4	3.07e-04	168	35	3	d4053b2fffb19e0376b8ceb92e87ec4447d96a3e
ToppCell	facs-Marrow-B-cells-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBE2O SAMD11 SLC2A4	3.07e-04	168	35	3	08fe8fa43c343c03f9a2f0b982192fde04a7c027
ToppCell	facs-Marrow-B-cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBE2O SAMD11 SLC2A4	3.07e-04	168	35	3	a61b39884851384cffd430079040546d125b2b40
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_T_CD8-Tnaive/CM_CD8\|GI_small-bowel / Manually curated celltypes from each tissue	PCYOX1L BBS9 BIVM	3.07e-04	168	35	3	c51244b4bdbfd961e2725306aa9cb25dd66d58bd
ToppCell	facs-Marrow-Granulocytes-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBE2O SAMD11 SLC2A4	3.17e-04	170	35	3	37c647f67505aa1ff12a198df1eeddd9f406fe15
ToppCell	facs-Marrow-Granulocytes-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBE2O SAMD11 SLC2A4	3.17e-04	170	35	3	b180ec9a1b79025a180c8559c27c31272410dea8
ToppCell	facs-Kidney-nan-18m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCNKA CLCNKB SLC2A4	3.28e-04	172	35	3	87a30a219b0a6979abb5fba292a2d8ea946fd849
ToppCell	facs-Kidney-nan-18m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCNKA CLCNKB SLC2A4	3.28e-04	172	35	3	5030ac31709cac236bb58f4ef9d545d24690411a
ToppCell	Bronchial_Biopsy-Epithelial-Ionocytes\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	APOB CLCNKA CLCNKB	3.40e-04	174	35	3	7e7b13de916cd4fa0fa6fb06e6b4942877afa9fb
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1-3_PAX6_NABP1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CFAP47 ADRA1A ENTPD3	3.45e-04	175	35	3	f7f8c16e81b26748a5323d70c542d06c02eccdff
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADRA1A TNXA ENTPD3	3.45e-04	175	35	3	9d09636a103daa8f622c3dbfd1f1536aaec3b6bb
ToppCell	Bronchial_Biopsy-Epithelial-Ionocytes\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	APOB CLCNKA CLCNKB	3.45e-04	175	35	3	13b8f7dc38c90b74d4a20a84a8705d8e2ec244f6
ToppCell	COVID-19-kidney-CD-IC-A\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DSCAM CLCNKA CLCNKB	3.51e-04	176	35	3	45028197364c64e93e3ffe86aff773d47a477d49
ToppCell	droplet-Marrow-nan-24m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBE2O SAMD11 SLC2A4	3.51e-04	176	35	3	f92063b72ebfeb9b192281dc63d6bf2759c78554
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SNED1 ANKRD40 SLC2A3	3.63e-04	178	35	3	375156ba1c7b8592bf733c75f24968161f7cfa09
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCNKA CLCNKB SLC2A4	3.75e-04	180	35	3	0b653b1b653b40f3b8711d1312029a4a8a4961db
ToppCell	droplet-Kidney-nan-18m-Epithelial-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APOB CLCNKA CLCNKB	3.75e-04	180	35	3	cd743f81838ba210e5bb63fe0870918d7d2b0112
ToppCell	droplet-Heart-4Chambers-18m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSCAM ACE CLCNKB	3.87e-04	182	35	3	f4b74c2756989812abe4e7055ec8918f69d56025
ToppCell	COVID-19-kidney-CD-IC-A\|kidney / Disease (COVID-19 only), tissue and cell type	DSCAM CLCNKA CLCNKB	3.94e-04	183	35	3	5c7597a5b2bf6a481ca2c7e68560179214150fa0
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCNKA CLCNKB SLC2A4	3.94e-04	183	35	3	6b5fa169477821355d1ab7aa11935cdfde1c339c
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCNKA CLCNKB SLC2A4	4.06e-04	185	35	3	af86e75096c1812ae27a78405355957ee8043d84
ToppCell	NS-moderate-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP47 C2orf81 DNAH7	4.06e-04	185	35	3	5e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell	droplet-Bladder-Unstain-18m-Endothelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACE SAMD11 SLC2A3	4.13e-04	186	35	3	e3a14f3ccadbf3211822c67b8956ee01f563307a
ToppCell	droplet-Heart-4Chambers-18m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSCAM ACE CLCNKB	4.13e-04	186	35	3	35c88cc4eb388811fcac4323b549e5897fa8dc27
ToppCell	droplet-Heart-4Chambers-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSCAM ACE CLCNKB	4.13e-04	186	35	3	d998c5b00083cf2a7cd5341a98b7374b4de73c63
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l39\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PPP1R3D ADRA1A SLC2A4	4.26e-04	188	35	3	a5e7a363fbd5ae4d9312cf6f9941413d6a5c0b4d
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCNKA CLCNKB SLC2A4	4.26e-04	188	35	3	14e120b20e76baa07b6510a94f0c2dcdfdd52357
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCNKA CLCNKB SLC2A4	4.33e-04	189	35	3	443359d90fafae0c1de6bdcce9e8c95df6ea4de8
ToppCell	facs-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCNKA CLCNKB SLC2A4	4.39e-04	190	35	3	68ba1934b2b3f0cec8efd229fe1db6e8be8a26b0
ToppCell	droplet-Kidney-nan-21m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCNKA CLCNKB SLC2A4	4.39e-04	190	35	3	c247562df3e1aa3173c9f01a74d5831f0764a1b2
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCNKA CLCNKB SLC2A4	4.39e-04	190	35	3	5cea8298c8336c136ba009630c9e48d4bc832cb2
ToppCell	facs-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCNKA CLCNKB SLC2A4	4.39e-04	190	35	3	010d7d13a3c16e614c36720ef690a505b9f3f7aa
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCNKA CLCNKB SLC2A4	4.46e-04	191	35	3	5a5b5402a077b3189ca156f2bac5f47ad780aebf
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCNKA CLCNKB SLC2A4	4.46e-04	191	35	3	78bcce497920cc5b3bef083eab50deb1cc82cd2e
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCNKA CLCNKB SLC2A4	4.46e-04	191	35	3	297bc79adc5fef211497819b4861b52cd26ac754
ToppCell	droplet-Kidney-nan-3m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCNKA CLCNKB SLC2A4	4.46e-04	191	35	3	e1ec165ba6578cefd88895e7e183190e79f733a4
ToppCell	droplet-Kidney-nan-18m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCNKA CLCNKB SLC2A4	4.53e-04	192	35	3	61c2caf6c838132ed5faa8791c288f2149eba2c8
ToppCell	droplet-Kidney-nan-18m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCNKA CLCNKB SLC2A4	4.53e-04	192	35	3	e19e3e8edcc08e4a67873bfb6e46489ca6c8756a
ToppCell	IPF-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	CFAP47 BBS9 DNAH7	4.60e-04	193	35	3	ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCell	droplet-Bladder-Unstain-18m-Endothelial-endothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADRA1A ACE SLC2A3	4.67e-04	194	35	3	9d7cbbcf995274019ca10be0562f114513ec197a
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_neuro-secretory\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	DSCAM CLCNKA CLCNKB	4.81e-04	196	35	3	a4cc02ea41479d24044bd2ca6441f85d683c0ca9
ToppCell	droplet-Bladder-nan-24m-Endothelial\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADRA1A SLC2A3 SLC2A4	4.81e-04	196	35	3	9a90dd26e7a43e3fd55e7c5d8354cfa4cdd5a6cc
ToppCell	COPD-Stromal-Fibroblast\|Stromal / Disease state, Lineage and Cell class	SNED1 TNXA SLC2A3	4.81e-04	196	35	3	4930eeb303d174c28fd91021723e26fdf1af9170
ToppCell	droplet-Bladder-nan-24m-Endothelial-endothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADRA1A SLC2A3 SLC2A4	4.81e-04	196	35	3	04dfef1bd4ebb0e9469ae80024dc177e469a2560
ToppCell	proximal-Epithelial-Ionocyte\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TMTC3 CLCNKA CLCNKB	4.88e-04	197	35	3	e5d5accefaacea5ed2e22f906f5bcbc75083f287
ToppCell	mLN-B_cell-B_cell_IgG_Plasma\|B_cell / Region, Cell class and subclass	SAMD11 IGHG4 ENTPD3	4.88e-04	197	35	3	bd1d01d6c49f68f5c85d84df96c90dd04b9de09b
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_airway_neuro-secretory\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	DSCAM CLCNKA CLCNKB	4.88e-04	197	35	3	ff4df77117165b6b25315e29b0722cc136eba607
ToppCell	proximal-Epithelial-Ionocyte-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TMTC3 CLCNKA CLCNKB	4.88e-04	197	35	3	f65c35761da7c168d5c6e4d7edf5dafa26652fe4
ToppCell	proximal-3-Epithelial-Ionocyte\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TMTC3 CLCNKA CLCNKB	4.88e-04	197	35	3	288492fc67d8e81349d38e82caf1f1890276b299
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	DSCAM CLCNKA CLCNKB	4.88e-04	197	35	3	8f009a15f154b3bb184b489da4722b7c27de7e11
ToppCell	droplet-Bladder-nan-24m-Endothelial-endothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADRA1A SLC2A3 SLC2A4	4.88e-04	197	35	3	488e85991c5e668afb7672942726d9295b8fc7d8
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_neuro-secretory\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	DSCAM CLCNKA CLCNKB	4.95e-04	198	35	3	2591e08e3fbee86ac40f11becd8147d6d39fded6
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	DSCAM CLCNKA CLCNKB	4.95e-04	198	35	3	62059185afdf66126a6fbc899ce611c47e7a0feb
ToppCell	Caecum-T_cell-Tfh\|Caecum / Region, Cell class and subclass	ACE SLC2A3 ENTPD3	5.03e-04	199	35	3	fb40f37d842f170ed101dfa3bffdb8f3b2c94f19
ToppCell	Caecum-(1)_T_cell-(16)_Tfh\|Caecum / shred on region, Cell_type, and subtype	ACE SLC2A3 ENTPD3	5.03e-04	199	35	3	d07d77ae426dd1164d80d7031f14befa0369d3e5
ToppCell	(07)_Ionocytes\|World / shred by cell type by condition	TMTC3 CLCNKA CLCNKB	5.03e-04	199	35	3	8194777d367405a7840787e977854b5c07e3bd6b
Disease	Bartter disease type 4B	CLCNKA CLCNKB	9.99e-07	2	30	2	cv:C4310805
Disease	BARTTER SYNDROME, TYPE 4B	CLCNKA CLCNKB	9.99e-07	2	30	2	C2751312
Disease	BARTTER SYNDROME, TYPE 4B, NEONATAL, WITH SENSORINEURAL DEAFNESS	CLCNKA CLCNKB	9.99e-07	2	30	2	C4310805
Disease	Bartter disease type 3 (implicated_via_orthology)	CLCNKA CLCNKB	9.99e-07	2	30	2	DOID:0110144 (implicated_via_orthology)
Disease	Bartter disease type 4b (is_implicated_in)	CLCNKA CLCNKB	9.99e-07	2	30	2	DOID:0110146 (is_implicated_in)
Disease	BARTTER SYNDROME, TYPE 4B, NEONATAL, WITH SENSORINEURAL DEAFNESS	CLCNKA CLCNKB	9.99e-07	2	30	2	613090
Disease	Bartter disease (implicated_via_orthology)	CLCNKA CLCNKB	9.99e-07	2	30	2	DOID:445 (implicated_via_orthology)
Disease	Bartter syndrome	CLCNKA CLCNKB	1.50e-05	6	30	2	cv:C0004775
Disease	nephrogenic diabetes insipidus (implicated_via_orthology)	CLCNKA CLCNKB	4.47e-05	10	30	2	DOID:12387 (implicated_via_orthology)
Disease	Streptozotocin Diabetes	ADRA1A ACE SLC2A4	1.80e-04	108	30	3	C0038433
Disease	Diabetes Mellitus, Experimental	ADRA1A ACE SLC2A4	1.80e-04	108	30	3	C0011853
Disease	Alloxan Diabetes	ADRA1A ACE SLC2A4	1.80e-04	108	30	3	C0002152
Disease	hypertension (is_implicated_in)	ADRA1A ACE CLCNKB	2.52e-04	121	30	3	DOID:10763 (is_implicated_in)
Disease	Coronary heart disease	APOB ACE	2.72e-04	24	30	2	C0010068
Disease	Behcet Syndrome	UBAC2 APOB	2.72e-04	24	30	2	C0004943
Disease	amino acid measurement	MOXD2P PCYOX1L ADRA1A DNAH7 SLC2A4	5.59e-04	678	30	5	EFO_0005134
Disease	Cardiovascular Diseases	APOB ACE	6.16e-04	36	30	2	C0007222
Disease	type 2 diabetes mellitus (is_implicated_in)	APOB ACE SLC2A4	6.92e-04	171	30	3	DOID:9352 (is_implicated_in)
Disease	diabetes mellitus (is_marker_for)	APOB SLC2A3	7.99e-04	41	30	2	DOID:9351 (is_marker_for)
Disease	Celiac Disease	APOB ACE	1.05e-03	47	30	2	C0007570
Disease	myopathy (implicated_via_orthology)	CLCNKA CLCNKB	1.09e-03	48	30	2	DOID:423 (implicated_via_orthology)
Disease	triglycerides to total lipids in medium LDL percentage	MICA APOB	1.19e-03	50	30	2	EFO_0022334
Disease	cholesteryl esters to total lipids in IDL percentage	MICA APOB	1.19e-03	50	30	2	EFO_0022247
Disease	diabetic retinopathy (is_implicated_in)	APOB ACE	1.19e-03	50	30	2	DOID:8947 (is_implicated_in)
Disease	triglycerides to total lipids in large LDL percentage	MICA APOB	1.24e-03	51	30	2	EFO_0022331
Disease	cholesterol to total lipids in large LDL percentage	MICA APOB	1.49e-03	56	30	2	EFO_0022235
Disease	hypertension (biomarker_via_orthology)	ADRA1A ACE SLC2A3	1.56e-03	227	30	3	DOID:10763 (biomarker_via_orthology)
Disease	cholesterol to total lipids in IDL percentage	MICA APOB	1.71e-03	60	30	2	EFO_0022233
Disease	triglycerides to total lipids in IDL percentage	MICA APOB	1.88e-03	63	30	2	EFO_0022329

Protein segments in the cluster

Peptide	Gene	Start	Entry
DFFTSLGLLPVPPEF	ACE	926	P12821
LPFFLVMPIGSFFPD	ADRA1A	286	P35348
ILGFQPPFEDIRFGP	BIVM	246	Q86UB2
PAPAFQPFFFTGAFP	ANKRD40	241	Q6AI12
PIEPPVFVGTLAFFT	ENTPD3	481	O75355
FILLGFFPPSRIGLF	OR2L3	11	Q8NG85
TLPFFMPLGFPALGL	MROH7	596	Q68CQ1
VFLLLAGIFPFAPPG	MICA	6	Q29983
FVAFFEIGPGPIPWF	SLC2A4	391	P14672
FGFPDPKLFPFANIL	PCYOX1L	346	Q8NBM8
FGRFLPGFLLPGPLA	BBS9	171	Q3SYG4
FLNFPRFQFPGKPGI	APOB	4196	P04114
EVGPPPVFWLSGFFF	DNAH7	3866	Q8WXX0
LVFVAFFEIGPGPIP	SLC2A3	371	P11169
VSPAAFFPLRPGIPF	C2orf81	396	A6NN90
APEFLGGPSVFLFPP	IGHG4	111	P01861
LFDPPFIFFTPVPLD	CFAP47	1306	Q6ZTR5
REFPFFTLTAFPPGF	C2CD5	346	Q86YS7
QLGFFTFPIHFIPPG	MOXD2P	341	A6NHM9
PPFIQPFEFPRFSIG	DSCAM	596	O60469
LLGFPPEFGFPEKIT	TRDMT1	351	O14717
PLDFVPEALFGILGF	RNF170	216	Q96K19
LFPGSTLPLGFPYAV	SAMD11	501	Q96NU1
EFGPFPFVIVPSFTF	RHOXF2B	271	P0C7M4
SGLRPLSVPFPFFGA	SNED1	51	Q8TER0
PFDLPEIFFFVALGG	CLCNKA	276	P51800
PFDLPEIFFFVALGG	CLCNKB	276	P51801
YPDIGFPLFPLSKGF	UBE2O	1251	Q9C0C9
FTFGFPVPPFLLELG	PPP1R3D	236	O95685
EFGPFPFVIVPSFTF	RHOXF2	271	Q9BQY4
PPGAFDSFLLRFGVP	TNXA	166	Q16473
LPSGFLAPVFALFVP	UBAC2	126	Q8NBM4
FPHPFLPNIDFVGGL	UGT2B28	266	Q9BY64
ALPFIPASNLFFPVG	TMTC3	356	Q6ZXV5
FGVFPAILSFPLDYP	UBE2G2	51	P60604