Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	serine-type endopeptidase activity	PCSK5 BMP1 ADAM17 CFI PCSK6	1.21e-05	190	32	5	GO:0004252
GeneOntologyMolecularFunction	serine-type peptidase activity	PCSK5 BMP1 ADAM17 CFI PCSK6	1.83e-05	207	32	5	GO:0008236
GeneOntologyMolecularFunction	serine hydrolase activity	PCSK5 BMP1 ADAM17 CFI PCSK6	2.05e-05	212	32	5	GO:0017171
GeneOntologyMolecularFunction	histone H3K27 methyltransferase activity	EZH2 EHMT2	3.72e-05	6	32	2	GO:0046976
GeneOntologyMolecularFunction	endopeptidase activity	PCSK5 BMP1 ADAM17 CFI ADAM21 PCSK6	5.43e-05	430	32	6	GO:0004175
GeneOntologyMolecularFunction	transcription corepressor binding	BCL6 EZH2 EHMT2	1.14e-04	59	32	3	GO:0001222
GeneOntologyMolecularFunction	extracellular matrix structural constituent	LAMA2 POMZP3 VWF LAMA1	2.23e-04	188	32	4	GO:0005201
GeneOntologyMolecularFunction	cell adhesion molecule binding	ADAM17 VWF TENM4 TENM3 TENM2 ITGB5	3.31e-04	599	32	6	GO:0050839
GeneOntologyMolecularFunction	peptidase activity	PCSK5 BMP1 ADAM17 CFI ADAM21 PCSK6	5.28e-04	654	32	6	GO:0008233
GeneOntologyMolecularFunction	Notch binding	ADAM17 MEGF10	8.52e-04	27	32	2	GO:0005112
GeneOntologyMolecularFunction	metalloendopeptidase activity	BMP1 ADAM17 ADAM21	9.24e-04	120	32	3	GO:0004222
GeneOntologyMolecularFunction	transcription coregulator binding	BCL6 EZH2 EHMT2	1.44e-03	140	32	3	GO:0001221
GeneOntologyMolecularFunction	histone H3 methyltransferase activity	EZH2 EHMT2	2.26e-03	44	32	2	GO:0140938
GeneOntologyMolecularFunction	integrin binding	ADAM17 VWF ITGB5	2.72e-03	175	32	3	GO:0005178
GeneOntologyMolecularFunction	metallopeptidase activity	BMP1 ADAM17 ADAM21	3.96e-03	200	32	3	GO:0008237
GeneOntologyMolecularFunction	protein-lysine N-methyltransferase activity	EZH2 EHMT2	5.31e-03	68	32	2	GO:0016279
GeneOntologyMolecularFunction	lysine N-methyltransferase activity	EZH2 EHMT2	5.46e-03	69	32	2	GO:0016278
GeneOntologyMolecularFunction	histone methyltransferase activity	EZH2 EHMT2	5.77e-03	71	32	2	GO:0042054
GeneOntologyMolecularFunction	calcium ion binding	BMP1 MEGF6 MEGF8 LRP1B TENM2	6.36e-03	749	32	5	GO:0005509
GeneOntologyMolecularFunction	promoter-specific chromatin binding	EZH2 EHMT2	7.81e-03	83	32	2	GO:1990841
GeneOntologyMolecularFunction	cargo receptor activity	LRP1B MEGF10	8.18e-03	85	32	2	GO:0038024
GeneOntologyMolecularFunction	protein methyltransferase activity	EZH2 EHMT2	1.18e-02	103	32	2	GO:0008276
GeneOntologyMolecularFunction	N-methyltransferase activity	EZH2 EHMT2	1.23e-02	105	32	2	GO:0008170
GeneOntologyMolecularFunction	structural molecule activity	LAMA2 KRTAP29-1 POMZP3 VWF LAMA1	1.29e-02	891	32	5	GO:0005198
GeneOntologyBiologicalProcess	positive regulation of integrin-mediated signaling pathway	LAMA2 PCSK5 LAMA1	1.22e-06	14	32	3	GO:2001046
GeneOntologyBiologicalProcess	regulation of integrin-mediated signaling pathway	LAMA2 PCSK5 LAMA1	5.88e-06	23	32	3	GO:2001044
GeneOntologyBiologicalProcess	integrin-mediated signaling pathway	LAMA2 PCSK5 ITGB5 LAMA1	3.93e-05	124	32	4	GO:0007229
GeneOntologyBiologicalProcess	signaling receptor ligand precursor processing	PCSK5 ADAM17 PCSK6	4.92e-05	46	32	3	GO:0140448
GeneOntologyBiologicalProcess	axon guidance	LAMA2 ADAM17 MEGF8 TENM2 LAMA1	7.21e-05	285	32	5	GO:0007411
GeneOntologyBiologicalProcess	neuron projection guidance	LAMA2 ADAM17 MEGF8 TENM2 LAMA1	7.33e-05	286	32	5	GO:0097485
GeneOntologyBiologicalProcess	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	TENM4 TENM3 TENM2	1.26e-04	63	32	3	GO:0007157
GeneOntologyBiologicalProcess	regulation of basement membrane organization	LAMA2 LAMA1	1.27e-04	11	32	2	GO:0110011
GeneOntologyBiologicalProcess	cell-cell adhesion	POMZP3 TENM4 BCL6 TENM3 TENM2 ITGB5 MEGF11 MEGF10	1.84e-04	1077	32	8	GO:0098609
GeneOntologyBiologicalProcess	morphogenesis of an epithelial sheet	MEGF8 ITGB5 LAMA1	2.04e-04	74	32	3	GO:0002011
GeneOntologyBiologicalProcess	positive regulation of cell adhesion	LAMA2 PCSK5 POMZP3 BCL6 MEGF10 LAMA1	2.32e-04	579	32	6	GO:0045785
GeneOntologyBiologicalProcess	regulation of muscle cell differentiation	LAMA2 EZH2 MEGF10 LAMA1	2.45e-04	199	32	4	GO:0051147
GeneOntologyBiologicalProcess	germinal center formation	ADAM17 BCL6	3.13e-04	17	32	2	GO:0002467
GeneOntologyBiologicalProcess	regulation of cell adhesion	LAMA2 PCSK5 POMZP3 BCL6 TENM3 MEGF10 LAMA1	4.54e-04	927	32	7	GO:0030155
GeneOntologyBiologicalProcess	regulation of embryonic development	LAMA2 TENM4 LAMA1	4.81e-04	99	32	3	GO:0045995
GeneOntologyBiologicalProcess	transforming growth factor beta receptor superfamily signaling pathway	KCP ADAM17 MEGF8 ITGB5 PCSK6	5.69e-04	445	32	5	GO:0141091
GeneOntologyCellularComponent	collagen-containing extracellular matrix	LAMA2 BMP1 POMZP3 VWF MEGF6 PCSK6 LAMA1	1.00e-05	530	31	7	GO:0062023
GeneOntologyCellularComponent	keratin filament	KRTAP29-1 KRTAP4-9 KRTAP4-1 KRTAP4-8	1.25e-05	97	31	4	GO:0045095
GeneOntologyCellularComponent	intermediate filament	KRTAP29-1 KRTAP4-9 KRTAP4-1 KRTAP4-8 KRTAP17-1	1.95e-05	227	31	5	GO:0005882
GeneOntologyCellularComponent	intermediate filament cytoskeleton	KRTAP29-1 KRTAP4-9 KRTAP4-1 KRTAP4-8 KRTAP17-1	3.95e-05	263	31	5	GO:0045111
GeneOntologyCellularComponent	extracellular matrix	LAMA2 BMP1 POMZP3 VWF MEGF6 PCSK6 LAMA1	3.96e-05	656	31	7	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	LAMA2 BMP1 POMZP3 VWF MEGF6 PCSK6 LAMA1	4.03e-05	658	31	7	GO:0030312
GeneOntologyCellularComponent	protein complex involved in cell adhesion	LAMA2 ITGB5 LAMA1	9.07e-05	59	31	3	GO:0098636
GeneOntologyCellularComponent	protein complex involved in cell-matrix adhesion	LAMA2 LAMA1	2.85e-04	17	31	2	GO:0098637
HumanPheno	Wide distal femoral metaphysis	BMP1 EZH2	3.60e-05	4	13	2	HP:0006387
HumanPheno	Abnormal distal femoral metaphysis morphology	BMP1 EZH2	5.99e-05	5	13	2	HP:0030299
HumanPheno	Wide femoral metaphysis	BMP1 EZH2	8.97e-05	6	13	2	HP:0006417
Domain	EGF	LAMA2 PCSK5 BMP1 TENM4 MEGF6 MEGF8 TENM3 LRP1B TENM2 ITGB5 MEGF11 MEGF10 PCSK6 LAMA1	6.51e-19	235	32	14	SM00181
Domain	EGF-like_dom	LAMA2 PCSK5 BMP1 TENM4 MEGF6 MEGF8 TENM3 LRP1B ADAM21 TENM2 MEGF11 MEGF10 PCSK6 LAMA1	1.48e-18	249	32	14	IPR000742
Domain	EGF-like_CS	LAMA2 BMP1 ADAM17 TENM4 MEGF6 MEGF8 TENM3 LRP1B ADAM21 TENM2 ITGB5 MEGF11 MEGF10 LAMA1	2.88e-18	261	32	14	IPR013032
Domain	EGF_1	LAMA2 BMP1 TENM4 MEGF6 MEGF8 TENM3 LRP1B ADAM21 TENM2 ITGB5 MEGF11 MEGF10 LAMA1	1.16e-16	255	32	13	PS00022
Domain	EGF_2	LAMA2 BMP1 TENM4 MEGF6 MEGF8 TENM3 LRP1B ADAM21 TENM2 ITGB5 MEGF11 MEGF10 LAMA1	1.92e-16	265	32	13	PS01186
Domain	EGF_3	BMP1 TENM4 MEGF6 MEGF8 TENM3 LRP1B ADAM21 TENM2 MEGF11 MEGF10	4.16e-12	235	32	10	PS50026
Domain	EGF_extracell	TENM4 MEGF6 TENM3 LRP1B ITGB5 MEGF11 MEGF10	7.77e-12	60	32	7	IPR013111
Domain	EGF_2	TENM4 MEGF6 TENM3 LRP1B ITGB5 MEGF11 MEGF10	7.77e-12	60	32	7	PF07974
Domain	Laminin_EGF	LAMA2 MEGF6 MEGF8 MEGF11 MEGF10 LAMA1	2.41e-11	35	32	6	PF00053
Domain	EGF_Lam	LAMA2 MEGF6 MEGF8 MEGF11 MEGF10 LAMA1	2.41e-11	35	32	6	SM00180
Domain	Laminin_EGF	LAMA2 MEGF6 MEGF8 MEGF11 MEGF10 LAMA1	4.09e-11	38	32	6	IPR002049
Domain	Rhs_assc_core	TENM4 TENM3 TENM2	4.57e-09	3	32	3	IPR022385
Domain	Growth_fac_rcpt_	PCSK5 BMP1 MEGF6 MEGF8 LRP1B PCSK6 LAMA1	7.00e-09	156	32	7	IPR009030
Domain	Tox-GHH_dom	TENM4 TENM3 TENM2	1.83e-08	4	32	3	IPR028916
Domain	TENEURIN_N	TENM4 TENM3 TENM2	1.83e-08	4	32	3	PS51361
Domain	Ten_N	TENM4 TENM3 TENM2	1.83e-08	4	32	3	IPR009471
Domain	Tox-GHH	TENM4 TENM3 TENM2	1.83e-08	4	32	3	PF15636
Domain	Ten_N	TENM4 TENM3 TENM2	1.83e-08	4	32	3	PF06484
Domain	YD	TENM4 TENM3 TENM2	4.56e-08	5	32	3	IPR006530
Domain	KAP	KRTAP29-1 KRTAP4-7 KRTAP4-9 KRTAP4-1 KRTAP4-8	4.57e-08	58	32	5	IPR002494
Domain	-	TENM4 TENM3 LRP1B TENM2	5.60e-07	39	32	4	2.120.10.30
Domain	Keratin_B2	KRTAP4-7 KRTAP4-9 KRTAP4-1 KRTAP4-8	6.21e-07	40	32	4	PF01500
Domain	6-blade_b-propeller_TolB-like	TENM4 TENM3 LRP1B TENM2	1.10e-06	46	32	4	IPR011042
Domain	NHL	TENM4 TENM3 TENM2	1.29e-06	13	32	3	PS51125
Domain	EGF_CA	BMP1 MEGF6 MEGF8 LRP1B TENM2	1.91e-06	122	32	5	SM00179
Domain	EGF-like_Ca-bd_dom	BMP1 MEGF6 MEGF8 LRP1B TENM2	2.07e-06	124	32	5	IPR001881
Domain	EMI_domain	MEGF6 MEGF11 MEGF10	2.52e-06	16	32	3	IPR011489
Domain	CarboxyPept-like_regulatory	TENM4 TENM3 TENM2	3.06e-06	17	32	3	IPR008969
Domain	EMI	MEGF6 MEGF11 MEGF10	3.06e-06	17	32	3	PS51041
Domain	EGF_CA	BMP1 MEGF6 MEGF8 LRP1B	1.37e-05	86	32	4	PF07645
Domain	hEGF	MEGF6 MEGF11 MEGF10	1.45e-05	28	32	3	PF12661
Domain	EGF_LAM_2	LAMA2 MEGF8 LAMA1	1.80e-05	30	32	3	PS50027
Domain	EGF_LAM_1	LAMA2 MEGF8 LAMA1	1.80e-05	30	32	3	PS01248
Domain	Galactose-bd-like	LAMA2 PCSK5 PCSK6 LAMA1	1.94e-05	94	32	4	IPR008979
Domain	EGF_Ca-bd_CS	BMP1 MEGF6 MEGF8 LRP1B	2.20e-05	97	32	4	IPR018097
Domain	EGF_CA	BMP1 MEGF6 MEGF8 LRP1B	2.38e-05	99	32	4	PS01187
Domain	ASX_HYDROXYL	BMP1 MEGF6 MEGF8 LRP1B	2.48e-05	100	32	4	PS00010
Domain	Laminin_aI	LAMA2 LAMA1	2.83e-05	5	32	2	IPR009254
Domain	Laminin_I	LAMA2 LAMA1	2.83e-05	5	32	2	PF06008
Domain	Laminin_II	LAMA2 LAMA1	2.83e-05	5	32	2	PF06009
Domain	Laminin_domII	LAMA2 LAMA1	2.83e-05	5	32	2	IPR010307
Domain	EGF-type_Asp/Asn_hydroxyl_site	BMP1 MEGF6 MEGF8 LRP1B	3.12e-05	106	32	4	IPR000152
Domain	Keratin_B2_2	KRTAP29-1 KRTAP4-1 KRTAP4-8	4.00e-05	39	32	3	PF13885
Domain	GF_recep_IV	PCSK5 PCSK6	4.25e-05	6	32	2	PF14843
Domain	GF_recep_IV	PCSK5 PCSK6	4.25e-05	6	32	2	IPR032778
Domain	Peptidase_S8_Asp-AS	PCSK5 PCSK6	4.25e-05	6	32	2	IPR023827
Domain	LDLR_class-A_CS	CFI LRP1B MAMDC4	4.32e-05	40	32	3	IPR023415
Domain	PrprotnconvertsP	PCSK5 PCSK6	5.94e-05	7	32	2	IPR002884
Domain	P_proprotein	PCSK5 PCSK6	5.94e-05	7	32	2	PF01483
Domain	S8_pro-domain	PCSK5 PCSK6	5.94e-05	7	32	2	IPR032815
Domain	-	PCSK5 PCSK6	5.94e-05	7	32	2	3.30.70.850
Domain	S8_pro-domain	PCSK5 PCSK6	5.94e-05	7	32	2	PF16470
Domain	EGF	BMP1 MEGF6 LRP1B ITGB5	6.13e-05	126	32	4	PF00008
Domain	Ldl_recept_a	CFI LRP1B MAMDC4	6.17e-05	45	32	3	PF00057
Domain	-	CFI LRP1B MAMDC4	6.60e-05	46	32	3	4.10.400.10
Domain	LDLRA_1	CFI LRP1B MAMDC4	7.50e-05	48	32	3	PS01209
Domain	LAMININ_IVA	LAMA2 LAMA1	7.91e-05	8	32	2	PS51115
Domain	Laminin_B	LAMA2 LAMA1	7.91e-05	8	32	2	PF00052
Domain	LamB	LAMA2 LAMA1	7.91e-05	8	32	2	SM00281
Domain	Laminin_IV	LAMA2 LAMA1	7.91e-05	8	32	2	IPR000034
Domain	LDrepeatLR_classA_rpt	CFI LRP1B MAMDC4	7.98e-05	49	32	3	IPR002172
Domain	LDLa	CFI LRP1B MAMDC4	7.98e-05	49	32	3	SM00192
Domain	LDLRA_2	CFI LRP1B MAMDC4	7.98e-05	49	32	3	PS50068
Domain	Peptidase_S8_His-AS	PCSK5 PCSK6	1.02e-04	9	32	2	IPR022398
Domain	PSI_integrin	MEGF8 ITGB5	1.02e-04	9	32	2	PF17205
Domain	Integin_beta_N	MEGF8 ITGB5	1.02e-04	9	32	2	IPR033760
Domain	Peptidase_S8_Ser-AS	PCSK5 PCSK6	1.02e-04	9	32	2	IPR023828
Domain	Peptidase_S8_subtilisin-rel	PCSK5 PCSK6	1.27e-04	10	32	2	IPR015500
Domain	SUBTILASE_ASP	PCSK5 PCSK6	1.27e-04	10	32	2	PS00136
Domain	SUBTILASE_HIS	PCSK5 PCSK6	1.27e-04	10	32	2	PS00137
Domain	SUBTILASE_SER	PCSK5 PCSK6	1.27e-04	10	32	2	PS00138
Domain	Peptidase_S8	PCSK5 PCSK6	1.55e-04	11	32	2	PF00082
Domain	Laminin_G_1	LAMA2 LAMA1	1.55e-04	11	32	2	PF00054
Domain	-	PCSK5 PCSK6	1.55e-04	11	32	2	3.40.50.200
Domain	Peptidase_S8/S53_dom	PCSK5 PCSK6	1.55e-04	11	32	2	IPR000209
Domain	Unchr_dom_Cys-rich	KCP VWF	2.19e-04	13	32	2	IPR014853
Domain	C8	KCP VWF	2.19e-04	13	32	2	SM00832
Domain	PLAC	PCSK5 PCSK6	2.55e-04	14	32	2	PF08686
Domain	TIL_dom	KCP VWF	2.55e-04	14	32	2	IPR002919
Domain	-	LAMA2 PCSK5 PCSK6	2.62e-04	73	32	3	2.60.120.260
Domain	LAMININ_NTER	LAMA2 LAMA1	3.36e-04	16	32	2	PS51117
Domain	VWFD	KCP VWF	3.36e-04	16	32	2	PS51233
Domain	Laminin_N	LAMA2 LAMA1	3.36e-04	16	32	2	PF00055
Domain	VWD	KCP VWF	3.36e-04	16	32	2	SM00216
Domain	VWF_type-D	KCP VWF	3.36e-04	16	32	2	IPR001846
Domain	Laminin_N	LAMA2 LAMA1	3.36e-04	16	32	2	IPR008211
Domain	VWD	KCP VWF	3.36e-04	16	32	2	PF00094
Domain	LamNT	LAMA2 LAMA1	3.36e-04	16	32	2	SM00136
Domain	MetalloPept_cat_dom	BMP1 ADAM17 ADAM21	3.56e-04	81	32	3	IPR024079
Domain	-	BMP1 ADAM17 ADAM21	3.56e-04	81	32	3	3.40.390.10
Domain	Propept_inh	PCSK5 PCSK6	3.81e-04	17	32	2	IPR009020
Domain	Furin_repeat	PCSK5 PCSK6	4.28e-04	18	32	2	IPR006212
Domain	FU	PCSK5 PCSK6	4.28e-04	18	32	2	SM00261
Domain	VWC_out	KCP VWF	4.78e-04	19	32	2	SM00215
Domain	PLAC	PCSK5 PCSK6	4.78e-04	19	32	2	IPR010909
Domain	PLAC	PCSK5 PCSK6	4.78e-04	19	32	2	PS50900
Domain	-	ADAM17 ADAM21	5.30e-04	20	32	2	4.10.70.10
Domain	DISIN	ADAM17 ADAM21	5.85e-04	21	32	2	SM00050
Domain	Disintegrin	ADAM17 ADAM21	5.85e-04	21	32	2	PF00200
Domain	ZINC_PROTEASE	BMP1 ADAM17 ADAM21	6.22e-04	98	32	3	PS00142
Pathway	REACTOME_KERATINIZATION	KRTAP29-1 KRTAP4-7 KRTAP4-9 KRTAP4-1 KRTAP4-8 PCSK6 KRTAP17-1	3.70e-08	217	23	7	M27640
Pathway	REACTOME_DEVELOPMENTAL_BIOLOGY	LAMA2 KRTAP29-1 KRTAP4-7 KRTAP4-9 DPF2 EZH2 KRTAP4-1 KRTAP4-8 PCSK6 LAMA1 KRTAP17-1	4.87e-06	1432	23	11	M509
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	LAMA2 BMP1 ADAM17 VWF ITGB5 LAMA1	6.57e-06	300	23	6	M610
Pathway	KEGG_ECM_RECEPTOR_INTERACTION	LAMA2 VWF ITGB5 LAMA1	9.53e-06	84	23	4	M7098
Pathway	REACTOME_KERATINIZATION	KRTAP29-1 KRTAP4-9 KRTAP4-1 KRTAP4-8	1.01e-04	153	23	4	MM15343
Pathway	REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS	LAMA2 ITGB5 LAMA1	1.16e-04	59	23	3	M27218
Pathway	REACTOME_PLASMA_LIPOPROTEIN_ASSEMBLY_REMODELING_AND_CLEARANCE	PCSK5 BMP1 PCSK6	1.35e-04	62	23	3	MM14686
Pathway	REACTOME_ASSEMBLY_OF_ACTIVE_LPL_AND_LIPC_LIPASE_COMPLEXES	PCSK5 PCSK6	1.39e-04	11	23	2	MM15559
Pathway	PID_INTEGRIN4_PATHWAY	LAMA2 LAMA1	1.39e-04	11	23	2	M158
Pathway	REACTOME_INTERACTION_WITH_CUMULUS_CELLS_AND_THE_ZONA_PELLUCIDA	POMZP3 ADAM21	1.39e-04	11	23	2	MM14897
Pathway	WP_FOCAL_ADHESION	LAMA2 VWF ITGB5 LAMA1	2.18e-04	187	23	4	MM15913
Pathway	REACTOME_PLASMA_LIPOPROTEIN_ASSEMBLY_REMODELING_AND_CLEARANCE	PCSK5 BMP1 PCSK6	2.37e-04	75	23	3	M27032
Pathway	REACTOME_ECM_PROTEOGLYCANS	LAMA2 ITGB5 LAMA1	2.47e-04	76	23	3	M27219
Pathway	KEGG_FOCAL_ADHESION	LAMA2 VWF ITGB5 LAMA1	2.76e-04	199	23	4	M7253
Pathway	WP_FOCAL_ADHESION	LAMA2 VWF ITGB5 LAMA1	2.76e-04	199	23	4	M39402
Pathway	REACTOME_ASSEMBLY_OF_ACTIVE_LPL_AND_LIPC_LIPASE_COMPLEXES	PCSK5 PCSK6	4.28e-04	19	23	2	M27839
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_E2F6	EZH2 EHMT2	7.47e-04	25	23	2	MM15546
Pathway	REACTOME_PLASMA_LIPOPROTEIN_REMODELING	PCSK5 PCSK6	7.47e-04	25	23	2	MM15562
Pathway	KEGG_MEDICUS_REFERENCE_ACTIVATION_OF_PRC2.2_BY_UBIQUITINATION_OF_H2AK119_IN_GERMLINE_GENES	EZH2 EHMT2	8.72e-04	27	23	2	M47941
Pathway	REACTOME_MET_ACTIVATES_PTK2_SIGNALING	LAMA2 LAMA1	1.08e-03	30	23	2	M27772
Pathway	REACTOME_LAMININ_INTERACTIONS	LAMA2 LAMA1	1.08e-03	30	23	2	M27216
Pathway	REACTOME_REPRODUCTION	POMZP3 ADAM21	1.08e-03	30	23	2	MM17211
Pathway	BIOCARTA_AGR_PATHWAY	LAMA2 LAMA1	1.15e-03	31	23	2	MM1343
Pathway	WP_TUMOR_SUPPRESSOR_ACTIVITY_OF_SMARCB1	DPF2 EZH2	1.15e-03	31	23	2	M39522
Pathway	WP_FBXL10_ENHANCEMENT_OF_MAPERK_SIGNALING_IN_DIFFUSE_LARGE_BCELL_LYMPHOMA	BCL6 EZH2	1.30e-03	33	23	2	M39800
Pathway	WP_ALPHA_6_BETA_4_SIGNALING	LAMA2 LAMA1	1.30e-03	33	23	2	M39503
Pathway	WP_FOCAL_ADHESION_PI3KAKTMTORSIGNALING	LAMA2 VWF ITGB5 LAMA1	1.33e-03	302	23	4	M39719
Pathway	REACTOME_PLASMA_LIPOPROTEIN_REMODELING	PCSK5 PCSK6	1.38e-03	34	23	2	M27842
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_E2F6	EZH2 EHMT2	1.38e-03	34	23	2	M27826
Pathway	REACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES	LAMA2 PCSK5 ADAM17 PCSK6 LAMA1	1.44e-03	532	23	5	M27870
Pathway	WP_FOCAL_ADHESION_PI3KAKTMTOR_SIGNALING_PATHWAY	LAMA2 VWF ITGB5 LAMA1	1.76e-03	326	23	4	MM15917
Pathway	REACTOME_MET_PROMOTES_CELL_MOTILITY	LAMA2 LAMA1	2.01e-03	41	23	2	M27778
Pathway	WP_PI3KAKT_SIGNALING	LAMA2 VWF ITGB5 LAMA1	2.03e-03	339	23	4	M39736
Pathway	REACTOME_PKMTS_METHYLATE_HISTONE_LYSINES	EZH2 EHMT2	2.52e-03	46	23	2	MM14933
Pathway	WP_MECP2_AND_ASSOCIATED_RETT_SYNDROME	BCL6 EZH2	2.52e-03	46	23	2	MM15949
Pathway	PID_A6B1_A6B4_INTEGRIN_PATHWAY	LAMA2 LAMA1	2.52e-03	46	23	2	M239
Pathway	WP_COMPLEMENT_AND_COAGULATION_CASCADES	VWF CFI	3.98e-03	58	23	2	M39649
Pathway	WP_DENGUE2_INTERACTIONS_WITH_COMPLEMENT_AND_COAGULATION_CASCADES	VWF CFI	4.12e-03	59	23	2	M48343
Pathway	WP_HISTONE_MODIFICATIONS	EZH2 EHMT2	4.98e-03	65	23	2	M39374
Pathway	WP_ALPHA_6_BETA_4_INTEGRIN_SIGNALING_PATHWAY	LAMA2 LAMA1	5.13e-03	66	23	2	MM15925
Pathway	PID_INTEGRIN1_PATHWAY	LAMA2 LAMA1	5.13e-03	66	23	2	M18
Pathway	KEGG_COMPLEMENT_AND_COAGULATION_CASCADES	VWF CFI	5.59e-03	69	23	2	M16894
Pathway	REACTOME_PKMTS_METHYLATE_HISTONE_LYSINES	EZH2 EHMT2	5.75e-03	70	23	2	M27231
Pathway	WP_MECP2_AND_ASSOCIATED_RETT_SYNDROME	BCL6 EZH2	6.24e-03	73	23	2	M39401
Pathway	WP_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY	LAMA2 ITGB5	6.40e-03	74	23	2	M39462
Pathway	KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC	LAMA2 ITGB5	6.40e-03	74	23	2	M16376
Pathway	REACTOME_SIGNALING_BY_NTRKS	PCSK5 PCSK6	6.57e-03	75	23	2	MM14652
Pathway	REACTOME_SIGNALING_BY_MET	LAMA2 LAMA1	7.27e-03	79	23	2	M27643
Pathway	REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION	DPF2 EZH2 EHMT2	7.84e-03	254	23	3	M27131
Pathway	KEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM	LAMA2 ITGB5	8.00e-03	83	23	2	M8728
Pathway	KEGG_SMALL_CELL_LUNG_CANCER	LAMA2 LAMA1	8.18e-03	84	23	2	M3228
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	BMP1 VWF MEGF6	8.19e-03	258	23	3	MM14572
Pathway	REACTOME_DEVELOPMENTAL_BIOLOGY	KRTAP29-1 KRTAP4-9 KRTAP4-1 KRTAP4-8	8.21e-03	502	23	4	MM14537
Pathway	REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS	VWF ITGB5	8.37e-03	85	23	2	M16441
Pubmed	Characterization of a cluster of human high/ultrahigh sulfur keratin-associated protein genes embedded in the type I keratin gene domain on chromosome 17q12-21.	KRTAP4-7 KRTAP4-9 KRTAP4-1 KRTAP4-8 KRTAP17-1	2.39e-10	37	33	5	11279113
Pubmed	Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.	PCSK5 VWF MEGF6 MEGF8 EHMT2 PCSK6	1.38e-09	118	33	6	21078624
Pubmed	Mouse ten-m/Odz is a new family of dimeric type II transmembrane proteins expressed in many tissues.	TENM4 TENM3 TENM2	3.11e-09	4	33	3	10225957
Pubmed	All four members of the Ten-m/Odz family of transmembrane proteins form dimers.	TENM4 TENM3 TENM2	3.11e-09	4	33	3	12000766
Pubmed	Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.	LAMA2 PCSK5 BMP1 ADAM17 VWF CFI LAMA1	3.14e-09	248	33	7	24006456
Pubmed	The mammalian Odz gene family: homologs of a Drosophila pair-rule gene with expression implying distinct yet overlapping developmental roles.	TENM4 TENM3 TENM2	2.72e-08	7	33	3	10625539
Pubmed	The murine Ten-m/Odz genes show distinct but overlapping expression patterns during development and in adult brain.	TENM4 TENM3 TENM2	2.72e-08	7	33	3	12915301
Pubmed	Distinct alpha 7A beta 1 and alpha 7B beta 1 integrin expression patterns during mouse development: alpha 7A is restricted to skeletal muscle but alpha 7B is expressed in striated muscle, vasculature, and nervous system.	LAMA2 VWF LAMA1	2.72e-08	7	33	3	8950511
Pubmed	Size polymorphisms in the human ultrahigh sulfur hair keratin-associated protein 4, KAP4, gene family.	KRTAP4-7 KRTAP4-1 KRTAP4-8	4.34e-08	8	33	3	15955084
Pubmed	Mapping homologs of Drosophila odd Oz (odz): Doc4/Odz4 to mouse chromosome 7, Odz1 to mouse chromosome 11; and ODZ3 to human chromosome Xq25.	TENM4 TENM3 TENM2	4.34e-08	8	33	3	10331952
Pubmed	Cartography of teneurin and latrophilin expression reveals spatiotemporal axis heterogeneity in the mouse hippocampus during development.	TENM4 TENM3 TENM2	9.30e-08	10	33	3	38713721
Pubmed	Binary Fate Choice between Closely Related Interneuronal Types Is Determined by a Fezf1-Dependent Postmitotic Transcriptional Switch.	TENM3 MEGF11 MEGF10	3.51e-07	15	33	3	31812516
Pubmed	Molecular evolution of the keratin associated protein gene family in mammals, role in the evolution of mammalian hair.	KRTAP29-1 KRTAP4-1 KRTAP4-8 KRTAP17-1	5.56e-07	69	33	4	18721477
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	LAMA2 BMP1 VWF MEGF6 LAMA1	6.45e-07	175	33	5	28071719
Pubmed	Transgenic overexpression of laminin alpha1 chain in laminin alpha2 chain-deficient mice rescues the disease throughout the lifespan.	LAMA2 LAMA1	8.73e-07	2	33	2	20544910
Pubmed	Conserved neuron promoting activity in Drosophila and vertebrate laminin alpha1.	LAMA2 LAMA1	8.73e-07	2	33	2	8663504
Pubmed	Laminin α1 reduces muscular dystrophy in dy2J mice.	LAMA2 LAMA1	8.73e-07	2	33	2	29544677
Pubmed	Laminin 2 attachment selects myofibroblasts from fetal mouse lung.	LAMA2 LAMA1	8.73e-07	2	33	2	9728058
Pubmed	Cell-surface processing of extracellular human immunodeficiency virus type 1 Vpr by proprotein convertases.	PCSK5 PCSK6	8.73e-07	2	33	2	18061232
Pubmed	Teneurins assemble into presynaptic nanoclusters that promote synapse formation via postsynaptic non-teneurin ligands.	TENM4 TENM3	8.73e-07	2	33	2	35484136
Pubmed	Identification of an isoform with an extremely large Cys-rich region of PC6, a Kex2-like processing endoprotease.	PCSK5 PCSK6	8.73e-07	2	33	2	8335106
Pubmed	The mammalian Ced-1 ortholog MEGF10/KIAA1780 displays a novel adhesion pattern.	MEGF11 MEGF10	8.73e-07	2	33	2	17498693
Pubmed	Identification and functional expression of a new member of the mammalian Kex2-like processing endoprotease family: its striking structural similarity to PACE4.	PCSK5 PCSK6	8.73e-07	2	33	2	8468318
Pubmed	Differential gene expression between sensory neocortical areas: potential roles for Ten_m3 and Bcl6 in patterning visual and somatosensory pathways.	BCL6 TENM3	8.73e-07	2	33	2	17478416
Pubmed	Distinct roles for laminin globular domains in laminin alpha1 chain mediated rescue of murine laminin alpha2 chain deficiency.	LAMA2 LAMA1	8.73e-07	2	33	2	20657839
Pubmed	Multiple Histone Lysine Methyltransferases Are Required for the Establishment and Maintenance of HIV-1 Latency.	EZH2 EHMT2	8.73e-07	2	33	2	28246360
Pubmed	Impaired fetal muscle development and JAK-STAT activation mark disease onset and progression in a mouse model for merosin-deficient congenital muscular dystrophy.	LAMA2 BCL6 LAMA1	1.18e-06	22	33	3	28334989
Pubmed	Putative complement control protein CSMD3 dysfunction impairs synaptogenesis and induces neurodevelopmental disorders.	LAMA2 TENM3 LAMA1	1.18e-06	22	33	3	35245678
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TENM4 MEGF8 TENM3 TENM2 MEGF11 KIAA0232	2.10e-06	407	33	6	12693553
Pubmed	Differential expression of laminin isoforms and alpha 6-beta 4 integrin subunits in the developing human and mouse intestine.	LAMA2 LAMA1	2.62e-06	3	33	2	7803849
Pubmed	Comparative cellular processing of the human immunodeficiency virus (HIV-1) envelope glycoprotein gp160 by the mammalian subtilisin/kexin-like convertases.	PCSK5 PCSK6	2.62e-06	3	33	2	8670066
Pubmed	Interplay between EZH2 and G9a Regulates CXCL10 Gene Repression in Idiopathic Pulmonary Fibrosis.	EZH2 EHMT2	2.62e-06	3	33	2	29053336
Pubmed	Expression of laminin chains during myogenic differentiation.	LAMA2 LAMA1	2.62e-06	3	33	2	7510707
Pubmed	Dystroglycan is a binding protein of laminin and merosin in peripheral nerve.	LAMA2 LAMA1	2.62e-06	3	33	2	7925941
Pubmed	Maturation of HIV envelope glycoprotein precursors by cellular endoproteases.	PCSK5 PCSK6	2.62e-06	3	33	2	11063880
Pubmed	Laminin alpha1 chain mediated reduction of laminin alpha2 chain deficient muscular dystrophy involves integrin alpha7beta1 and dystroglycan.	LAMA2 LAMA1	2.62e-06	3	33	2	16504180
Pubmed	Control of cognition and adaptive behavior by the GLP/G9a epigenetic suppressor complex.	EZH2 EHMT2	2.62e-06	3	33	2	20005824
Pubmed	The histone H3 lysine 9 methyltransferases G9a and GLP regulate polycomb repressive complex 2-mediated gene silencing.	EZH2 EHMT2	2.62e-06	3	33	2	24389103
Pubmed	A central role for G9a and EZH2 in the epigenetic silencing of cyclooxygenase-2 in idiopathic pulmonary fibrosis.	EZH2 EHMT2	2.62e-06	3	33	2	24652950
Pubmed	Brain alpha-dystroglycan displays unique glycoepitopes and preferential binding to laminin-10/11.	LAMA2 LAMA1	2.62e-06	3	33	2	16709410
Pubmed	MEGF10 and MEGF11 mediate homotypic interactions required for mosaic spacing of retinal neurons.	ITGB5 MEGF11 MEGF10	4.99e-06	35	33	3	22407321
Pubmed	CDMP1/GDF5 has specific processing requirements that restrict its action to joint surfaces.	PCSK5 PCSK6	5.23e-06	4	33	2	16829522
Pubmed	Ezh2 programs TFH differentiation by integrating phosphorylation-dependent activation of Bcl6 and polycomb-dependent repression of p19Arf.	BCL6 EZH2	5.23e-06	4	33	2	30575739
Pubmed	Cellular processing of the nerve growth factor precursor by the mammalian pro-protein convertases.	PCSK5 PCSK6	5.23e-06	4	33	2	8615794
Pubmed	Neurotrophin secretion: current facts and future prospects.	PCSK5 PCSK6	5.23e-06	4	33	2	12787574
Pubmed	Beta1 integrins control the formation of cell chains in the adult rostral migratory stream.	LAMA2 ITGB5	5.23e-06	4	33	2	17344408
Pubmed	Laminin alpha 1, alpha 2, alpha 4 and beta 1 chain mRNA expression in mouse embryonic, neonatal, and adult hearts.	LAMA2 LAMA1	5.23e-06	4	33	2	9201115
Pubmed	Organisation of extracellular matrix proteins laminin and agrin in pericapillary basal laminae in mouse brain.	LAMA2 LAMA1	5.23e-06	4	33	2	32072250
Pubmed	BCL-6 promotes the methylation of miR-34a by recruiting EZH2 and upregulating CTRP9 to protect ischemic myocardial injury.	BCL6 EZH2	5.23e-06	4	33	2	33502806
Pubmed	Distribution and isolation of four laminin variants; tissue restricted distribution of heterotrimers assembled from five different subunits.	LAMA2 LAMA1	5.23e-06	4	33	2	2099832
Pubmed	Desialylation of O-glycans on glycoprotein Ibα drives receptor signaling and platelet clearance.	ADAM17 VWF	5.23e-06	4	33	2	31974202
Pubmed	The proprotein convertases furin and PACE4 play a significant role in tumor progression.	PCSK5 PCSK6	5.23e-06	4	33	2	10900462
Pubmed	Retroviral envelope glycoprotein processing: structural investigation of the cleavage site.	PCSK5 PCSK6	5.23e-06	4	33	2	9521771
Pubmed	Molecular recognition by LARGE is essential for expression of functional dystroglycan.	LAMA2 LAMA1	5.23e-06	4	33	2	15210115
Pubmed	CHD4 Has Oncogenic Functions in Initiating and Maintaining Epigenetic Suppression of Multiple Tumor Suppressor Genes.	EZH2 EHMT2	5.23e-06	4	33	2	28486105
Pubmed	BMP1-like proteinases are essential to the structure and wound healing of skin.	LAMA2 BMP1	5.23e-06	4	33	2	27363389
Pubmed	Expression and distribution of laminin alpha1 and alpha2 chains in embryonic and adult mouse tissues: an immunochemical approach.	LAMA2 LAMA1	8.72e-06	5	33	2	11969289
Pubmed	PRC2 and EHMT1 regulate H3K27me2 and H3K27me3 establishment across the zygote genome.	EZH2 EHMT2	8.72e-06	5	33	2	33311485
Pubmed	Dynamic patterns of histone lysine methylation in the developing retina.	EZH2 EHMT2	8.72e-06	5	33	2	20671280
Pubmed	Regulation of prohepcidin processing and activity by the subtilisin-like proprotein convertases Furin, PC5, PACE4 and PC7.	PCSK5 PCSK6	8.72e-06	5	33	2	18664504
Pubmed	Differential expression of five laminin alpha (1-5) chains in developing and adult mouse kidney.	LAMA2 LAMA1	8.72e-06	5	33	2	9415429
Pubmed	Expression of laminin isoforms in mouse myogenic cells in vitro and in vivo.	LAMA2 LAMA1	8.72e-06	5	33	2	8719886
Pubmed	Processing of prothyrotropin-releasing hormone by the family of prohormone convertases.	PCSK5 PCSK6	8.72e-06	5	33	2	9242664
Pubmed	Complete sequence, recombinant analysis and binding to laminins and sulphated ligands of the N-terminal domains of laminin alpha3B and alpha5 chains.	LAMA2 LAMA1	8.72e-06	5	33	2	11829758
Pubmed	Proprotein convertase expression and localization in epidermis: evidence for multiple roles and substrates.	PCSK5 PCSK6	8.72e-06	5	33	2	11380615
Pubmed	Laminin alpha 2 chain (M chain) is found within the pathway of avian and murine retinal projections.	LAMA2 LAMA1	8.72e-06	5	33	2	8613743
Pubmed	Differential expression of laminin alpha chains during murine tooth development.	LAMA2 LAMA1	8.72e-06	5	33	2	9389447
Pubmed	Genome-wide characterization of Foxa2 targets reveals upregulation of floor plate genes and repression of ventrolateral genes in midbrain dopaminergic progenitors.	LAMA2 BCL6 ITGB5	1.07e-05	45	33	3	22696295
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	VWF MEGF6 MEGF8 MEGF11 KIAA0232 MEGF10	1.30e-05	560	33	6	21653829
Pubmed	Cross-linking of laminin-nidogen complexes by tissue transglutaminase. A novel mechanism for basement membrane stabilization.	LAMA2 LAMA1	1.31e-05	6	33	2	1678389
Pubmed	Structural elucidation of full-length nidogen and the laminin-nidogen complex in solution.	LAMA2 LAMA1	1.31e-05	6	33	2	23948589
Pubmed	Essential role of alpha 6 integrins in cortical and retinal lamination.	LAMA2 LAMA1	1.31e-05	6	33	2	9742403
Pubmed	Entactin: structure and function.	LAMA2 LAMA1	1.31e-05	6	33	2	2119632
Pubmed	HIV-protein-mediated alterations in T cell interactions with the extracellular matrix proteins and endothelium.	LAMA2 LAMA1	1.31e-05	6	33	2	9597096
Pubmed	Ethanol increases fetal human neurosphere size and alters adhesion molecule gene expression.	ITGB5 LAMA1	1.31e-05	6	33	2	18162078
Pubmed	Absence of post-phosphoryl modification in dystroglycanopathy mouse models and wild-type tissues expressing non-laminin binding form of α-dystroglycan.	LAMA2 LAMA1	1.31e-05	6	33	2	22270369
Pubmed	Identification of the paired basic convertases implicated in HIV gp160 processing based on in vitro assays and expression in CD4(+) cell lines.	PCSK5 PCSK6	1.31e-05	6	33	2	8940009
Pubmed	Murine subtilisin-like proteinase SPC6 is expressed during embryonic implantation, somitogenesis, and skeletal formation.	PCSK5 PCSK6	1.31e-05	6	33	2	9291583
Pubmed	The cysteine-rich domain of the secreted proprotein convertases PC5A and PACE4 functions as a cell surface anchor and interacts with tissue inhibitors of metalloproteinases.	PCSK5 PCSK6	1.31e-05	6	33	2	16135528
Pubmed	Impaired primary mouse myotube formation on crosslinked type I collagen films is enhanced by laminin and entactin.	LAMA2 LAMA1	1.31e-05	6	33	2	26555376
Pubmed	Protein kinase C signaling dysfunction in von Willebrand disease (p.V1316M) type 2B platelets.	ADAM17 VWF	1.31e-05	6	33	2	29925524
Pubmed	Effect of basement membrane entactin on epidermal cell attachment and growth.	LAMA2 LAMA1	1.31e-05	6	33	2	3794389
Pubmed	Laminin regulates PDGFRβ(+) cell stemness and muscle development.	LAMA2 LAMA1	1.31e-05	6	33	2	27138650
Pubmed	Laminin-nidogen complex. Extraction with chelating agents and structural characterization.	LAMA2 LAMA1	1.31e-05	6	33	2	3109910
Pubmed	Potential target genes of EMX2 include Odz/Ten-M and other gene families with implications for cortical patterning.	TENM4 TENM3 TENM2	1.57e-05	51	33	3	16919471
Pubmed	Glial precursors clear sensory neuron corpses during development via Jedi-1, an engulfment receptor.	MEGF11 MEGF10	1.83e-05	7	33	2	19915564
Pubmed	Proteolytic processing in the secretory pathway.	PCSK5 PCSK6	1.83e-05	7	33	2	10409610
Pubmed	The family of subtilisin/kexin like pro-protein and pro-hormone convertases: divergent or shared functions.	PCSK5 PCSK6	1.83e-05	7	33	2	7819324
Pubmed	Laminin isoforms in fetal and adult human adrenal cortex.	LAMA2 LAMA1	1.83e-05	7	33	2	14557481
Pubmed	Abscence of laminin alpha1 chain in the skeletal muscle of dystrophic dy/dy mice.	LAMA2 LAMA1	1.83e-05	7	33	2	9390664
Pubmed	Chromosomal assignment of the genes for proprotein convertases PC4, PC5, and PACE 4 in mouse and human.	PCSK5 PCSK6	2.44e-05	8	33	2	7782070
Pubmed	Laminin-1 promotes differentiation of fetal mouse pancreatic beta-cells.	LAMA2 LAMA1	2.44e-05	8	33	2	10102687
Pubmed	Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases.	PCSK5 PCSK6	2.44e-05	8	33	2	9885250
Pubmed	Cellular localization and role of prohormone convertases in the processing of pro-melanin concentrating hormone in mammals.	PCSK5 PCSK6	2.44e-05	8	33	2	10037747
Pubmed	Reduced Dnmt3a increases Gdf5 expression with suppressed satellite cell differentiation and impaired skeletal muscle regeneration.	EZH2 EHMT2	2.44e-05	8	33	2	29146735
Pubmed	Roles for laminin in embryogenesis: exencephaly, syndactyly, and placentopathy in mice lacking the laminin alpha5 chain.	LAMA2 LAMA1	2.44e-05	8	33	2	9852162
Pubmed	Cloning and expression analyses of mouse dystroglycan gene: specific expression in maternal decidua at the peri-implantation stage.	LAMA2 LAMA1	2.44e-05	8	33	2	8872465
Pubmed	Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening.	MEGF6 MEGF8	3.13e-05	9	33	2	9693030
Pubmed	Expression of laminin alpha1, alpha2, alpha4, and alpha5 chains, fibronectin, and tenascin-C in skeletal muscle of dystrophic 129ReJ dy/dy mice.	LAMA2 LAMA1	3.13e-05	9	33	2	9882526
Pubmed	The activation and physiological functions of the proprotein convertases.	PCSK5 PCSK6	3.13e-05	9	33	2	18343183
Interaction	CACNA1A interactions	PCSK5 VWF BCL6 MEGF6 MEGF8 EHMT2 PCSK6	4.81e-10	123	30	7	int:CACNA1A
Interaction	LCE3D interactions	PCSK5 TENM4 TRIM42 KRTAP4-1 KRTAP17-1	7.21e-08	73	30	5	int:LCE3D
Interaction	FBXO2 interactions	PCSK5 BMP1 ADAM17 MEGF8 TENM3 LRP1B ITGB5 LAMA1	1.10e-07	411	30	8	int:FBXO2
Interaction	MSTN interactions	BMP1 MEGF8 ADAM21 PCSK6	1.58e-07	33	30	4	int:MSTN
Interaction	HOXA1 interactions	PCSK5 KRTAP4-7 VWF MEGF6 MEGF8 TRIM42 KRTAP4-1	7.26e-07	356	30	7	int:HOXA1
Interaction	IL5RA interactions	PCSK5 BMP1 MEGF8 TENM3 PCSK6	1.02e-06	124	30	5	int:IL5RA
Interaction	TRGV3 interactions	BMP1 MEGF8 ITGB5 PCSK6	1.29e-06	55	30	4	int:TRGV3
Interaction	LYPD1 interactions	PCSK5 MEGF8 ADAM21 ITGB5	1.60e-06	58	30	4	int:LYPD1
Interaction	LCE3C interactions	PCSK5 TRIM42 KRTAP4-1 KRTAP17-1	2.86e-06	67	30	4	int:LCE3C
Interaction	OTX1 interactions	PCSK5 KRTAP4-7 TRIM42 KRTAP4-1 KRTAP17-1	3.08e-06	155	30	5	int:OTX1
Interaction	LCE3A interactions	PCSK5 TRIM42 KRTAP4-1 KRTAP17-1	4.75e-06	76	30	4	int:LCE3A
Interaction	SMCP interactions	PCSK5 KRTAP4-7 TRIM42 KRTAP4-1	5.55e-06	79	30	4	int:SMCP
Interaction	LCE2C interactions	PCSK5 TRIM42 KRTAP4-1 KRTAP17-1	8.53e-06	88	30	4	int:LCE2C
Interaction	SHFL interactions	PCSK5 TENM4 TRIM42 KRTAP17-1	1.26e-05	97	30	4	int:SHFL
Interaction	NCR3 interactions	PCSK5 BMP1 ADAM17 PCSK6	2.91e-05	120	30	4	int:NCR3
Interaction	NUFIP2 interactions	PCSK5 VWF MEGF6 TRIM42 KRTAP4-1 MEGF11	2.95e-05	417	30	6	int:NUFIP2
Interaction	CFC1 interactions	PCSK5 BMP1 MEGF8 PCSK6	3.52e-05	126	30	4	int:CFC1
Interaction	CATSPER1 interactions	KRTAP4-7 TRIM42 KRTAP4-1 KRTAP17-1	3.52e-05	126	30	4	int:CATSPER1
Interaction	PATE1 interactions	LRP1B ADAM21 ITGB5	5.24e-05	49	30	3	int:PATE1
Interaction	SLURP1 interactions	PCSK5 BMP1 MEGF8 ADAM21	5.93e-05	144	30	4	int:SLURP1
Interaction	MFAP5 interactions	VWF MEGF6 KIAA0232	6.26e-05	52	30	3	int:MFAP5
Interaction	ITGB5 interactions	BCL6 EHMT2 ADAM21 ITGB5	6.42e-05	147	30	4	int:ITGB5
Interaction	KLK15 interactions	BMP1 ADAM21 ITGB5 PCSK6	7.13e-05	151	30	4	int:KLK15
Interaction	BTNL2 interactions	BMP1 MEGF8 ADAM21 ITGB5	7.89e-05	155	30	4	int:BTNL2
Interaction	INSL5 interactions	PCSK5 ADAM17 ITGB5	8.69e-05	58	30	3	int:INSL5
Interaction	SDF2L1 interactions	PCSK5 BMP1 ADAM17 MEGF8 PCSK6	1.04e-04	322	30	5	int:SDF2L1
Interaction	DOCK2 interactions	PCSK5 TENM4 KRTAP17-1	1.28e-04	66	30	3	int:DOCK2
Interaction	CCL3 interactions	PCSK5 BMP1 BCL6 LAMA1	1.35e-04	178	30	4	int:CCL3
Interaction	LCE1D interactions	PCSK5 TRIM42 KRTAP4-1	1.52e-04	70	30	3	int:LCE1D
Interaction	FIBIN interactions	BMP1 MEGF8 PCSK6	1.59e-04	71	30	3	int:FIBIN
Interaction	ATN1 interactions	PCSK5 MEGF6 MEGF8 MEGF11	1.63e-04	187	30	4	int:ATN1
Interaction	GLRX3 interactions	PCSK5 KRTAP4-7 BCL6 TRIM42	1.77e-04	191	30	4	int:GLRX3
Interaction	LCE2D interactions	TRIM42 KRTAP4-1 KRTAP17-1	1.80e-04	74	30	3	int:LCE2D
Interaction	PLSCR4 interactions	PCSK5 TENM4 TRIM42	1.87e-04	75	30	3	int:PLSCR4
Interaction	IGFL3 interactions	PCSK5 LRP1B LAMA1	1.87e-04	75	30	3	int:IGFL3
Interaction	RELB interactions	DPF2 EZH2 EHMT2	2.10e-04	78	30	3	int:RELB
Interaction	KRTAP3-2 interactions	PCSK5 TRIM42 ITGB5	2.18e-04	79	30	3	int:KRTAP3-2
Interaction	LCE1B interactions	TRIM42 KRTAP4-1 KRTAP17-1	2.71e-04	85	30	3	int:LCE1B
Interaction	SIRPD interactions	MEGF8 ADAM21 PCSK6	2.80e-04	86	30	3	int:SIRPD
Interaction	MAZ interactions	DPF2 EZH2 EHMT2	2.80e-04	86	30	3	int:MAZ
Interaction	LY86 interactions	PCSK5 BMP1 ADAM21 PCSK6	2.88e-04	217	30	4	int:LY86
Interaction	KRTAP10-8 interactions	PCSK5 KRTAP4-7 TRIM42 ITGB5 KRTAP17-1	2.88e-04	401	30	5	int:KRTAP10-8
Interaction	OS9 interactions	BMP1 TENM3 LRP1B LAMA1	2.98e-04	219	30	4	int:OS9
Interaction	LRRC3 interactions	ADAM17 ADAM21	3.23e-04	18	30	2	int:LRRC3
Interaction	ELSPBP1 interactions	BMP1 MEGF8 PCSK6	3.42e-04	92	30	3	int:ELSPBP1
Interaction	LCE1F interactions	PCSK5 TRIM42 KRTAP4-1	3.42e-04	92	30	3	int:LCE1F
Interaction	RLN1 interactions	ADAM17 LRP1B ADAM21	3.53e-04	93	30	3	int:RLN1
Interaction	MX2 interactions	EZH2 EHMT2	3.61e-04	19	30	2	int:MX2
Interaction	KRTAP5-6 interactions	TRIM42 KRTAP4-1 KRTAP17-1	3.64e-04	94	30	3	int:KRTAP5-6
Interaction	KRTAP10-9 interactions	PCSK5 EZH2 TRIM42 ITGB5	4.28e-04	241	30	4	int:KRTAP10-9
Interaction	LCOR interactions	VWF EZH2 EHMT2 LRP1B	4.35e-04	242	30	4	int:LCOR
Interaction	GGH interactions	BMP1 MEGF8 ADAM21 PCSK6	4.42e-04	243	30	4	int:GGH
Interaction	ZNF518B interactions	EZH2 EHMT2	4.86e-04	22	30	2	int:ZNF518B
Interaction	GNE interactions	TRIM42 KRTAP4-1 KRTAP17-1	4.90e-04	104	30	3	int:GNE
Interaction	YY1 interactions	BCL6 EZH2 TRIM42 EHMT2 KRTAP17-1	5.08e-04	454	30	5	int:YY1
Interaction	EDN3 interactions	BMP1 MEGF8 PCSK6	5.47e-04	108	30	3	int:EDN3
Interaction	ATXN7 interactions	VWF MEGF6 MEGF8	5.62e-04	109	30	3	int:ATXN7
Interaction	LMAN2L interactions	ADAM17 EZH2 TENM3	5.92e-04	111	30	3	int:LMAN2L
Interaction	PCSK5 interactions	PCSK5 TRIM42 PCSK6	6.08e-04	112	30	3	int:PCSK5
Interaction	COL7A1 interactions	BMP1 LAMA1	6.29e-04	25	30	2	int:COL7A1
Interaction	SPP1 interactions	BCL6 EZH2 ITGB5	6.40e-04	114	30	3	int:SPP1
Interaction	PSMA1 interactions	DPF2 BCL6 TRIM42 KRTAP4-1 EHMT2	6.54e-04	480	30	5	int:PSMA1
Interaction	PMCH interactions	PCSK5 PCSK6	6.81e-04	26	30	2	int:PMCH
Interaction	ADAMTS13 interactions	VWF KIAA0232	6.81e-04	26	30	2	int:ADAMTS13
Interaction	PPARD interactions	BCL6 EHMT2 ITGB5	6.91e-04	117	30	3	int:PPARD
Interaction	LYZL1 interactions	BMP1 ADAM21 PCSK6	7.08e-04	118	30	3	int:LYZL1
Interaction	CEACAM8 interactions	PCSK5 TENM3 ITGB5	7.25e-04	119	30	3	int:CEACAM8
Interaction	DNASE1L1 interactions	BMP1 ADAM17 MEGF8	7.43e-04	120	30	3	int:DNASE1L1
Interaction	PRG2 interactions	PCSK5 BMP1 ADAM21 PCSK6	8.03e-04	285	30	4	int:PRG2
Interaction	HOXB9 interactions	PCSK5 TENM4 KRTAP17-1	8.18e-04	124	30	3	int:HOXB9
Interaction	CBLN4 interactions	BMP1 MEGF8 PCSK6	8.76e-04	127	30	3	int:CBLN4
Interaction	MBD3 interactions	DPF2 BCL6 EZH2 EHMT2	9.13e-04	295	30	4	int:MBD3
Interaction	RCN3 interactions	EZH2 PCSK6	9.70e-04	31	30	2	int:RCN3
Interaction	GPIHBP1 interactions	PCSK5 BMP1 PCSK6	1.00e-03	133	30	3	int:GPIHBP1
Interaction	TALDO1 interactions	DPF2 BCL6 EZH2	1.05e-03	135	30	3	int:TALDO1
Interaction	GFI1B interactions	MEGF6 MEGF8 EHMT2	1.07e-03	136	30	3	int:GFI1B
Interaction	ASPHD2 interactions	MAMDC4 ADAM21	1.17e-03	34	30	2	int:ASPHD2
Interaction	FSTL4 interactions	BMP1 PCSK6	1.17e-03	34	30	2	int:FSTL4
Interaction	BTLA interactions	BMP1 PCSK6	1.24e-03	35	30	2	int:BTLA
Interaction	EDIL3 interactions	EZH2 ITGB5	1.24e-03	35	30	2	int:EDIL3
Interaction	ZNF408 interactions	LRP1B KIAA0232 LAMA1	1.28e-03	145	30	3	int:ZNF408
Interaction	CLEC2B interactions	ADAM17 ADAM21 ITGB5	1.34e-03	147	30	3	int:CLEC2B
Interaction	CCL26 interactions	LRP1B KIAA0232	1.38e-03	37	30	2	int:CCL26
Cytoband	17q21.2	KRTAP29-1 KRTAP4-7 KRTAP4-9 KRTAP4-8	1.96e-07	70	33	4	17q21.2
Cytoband	Ensembl 112 genes in cytogenetic band chr17q21	KRTAP29-1 KRTAP4-7 KRTAP4-9 KRTAP4-1 KRTAP4-8 KRTAP17-1	1.01e-06	473	33	6	chr17q21
Cytoband	17q12-q21	KRTAP4-1 KRTAP17-1	2.45e-04	32	33	2	17q12-q21
GeneFamily	Keratin associated proteins	KRTAP29-1 KRTAP4-7 KRTAP4-9 KRTAP4-1 KRTAP4-8 KRTAP17-1	3.88e-09	109	23	6	619
GeneFamily	Proprotein convertase subtilisin/kexin family	PCSK5 PCSK6	5.54e-05	9	23	2	973
GeneFamily	Laminin subunits	LAMA2 LAMA1	1.01e-04	12	23	2	626
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	ADAM17 ADAM21	5.33e-04	27	23	2	47
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	EZH2 EHMT2	8.47e-04	34	23	2	487
Coexpression	NABA_MATRISOME	LAMA2 PCSK5 KCP BMP1 POMZP3 ADAM17 VWF MEGF6 MEGF8 ADAM21 MEGF11 MEGF10 PCSK6 LAMA1	5.86e-12	1008	33	14	MM17056
Coexpression	NABA_MATRISOME	LAMA2 PCSK5 KCP BMP1 POMZP3 ADAM17 VWF MEGF6 MEGF8 ADAM21 MEGF11 MEGF10 PCSK6 LAMA1	7.42e-12	1026	33	14	M5889
Coexpression	NABA_MATRISOME_ASSOCIATED	PCSK5 BMP1 ADAM17 MEGF6 MEGF8 ADAM21 MEGF11 MEGF10 PCSK6	2.23e-07	738	33	9	MM17058
Coexpression	NABA_MATRISOME_ASSOCIATED	PCSK5 BMP1 ADAM17 MEGF6 MEGF8 ADAM21 MEGF11 MEGF10 PCSK6	2.58e-07	751	33	9	M5885
Coexpression	NABA_ECM_GLYCOPROTEINS	LAMA2 KCP POMZP3 VWF LAMA1	3.92e-06	191	33	5	MM17059
Coexpression	NABA_ECM_GLYCOPROTEINS	LAMA2 KCP POMZP3 VWF LAMA1	4.45e-06	196	33	5	M3008
Coexpression	NABA_ECM_REGULATORS	PCSK5 BMP1 ADAM17 ADAM21 PCSK6	1.14e-05	238	33	5	M3468
Coexpression	NABA_ECM_REGULATORS	PCSK5 BMP1 ADAM17 ADAM21 PCSK6	1.24e-05	242	33	5	MM17062
Coexpression	NABA_CORE_MATRISOME	LAMA2 KCP POMZP3 VWF LAMA1	2.09e-05	270	33	5	MM17057
Coexpression	NABA_CORE_MATRISOME	LAMA2 KCP POMZP3 VWF LAMA1	2.29e-05	275	33	5	M5884
Coexpression	HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	LAMA2 BMP1 ITGB5 LAMA1	1.13e-04	200	33	4	M5930
Coexpression	GAO_ESOPHAGUS_25W_C4_FGFR1HIGH_EPITHELIAL_CELLS	LAMA2 BMP1 TENM4 PCSK6	1.32e-04	208	33	4	M39139
CoexpressionAtlas	facebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K4	LAMA2 PCSK5 KCP BMP1 VWF TENM4 MEGF8 TENM3 ITGB5	1.04e-05	1148	28	9	facebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K4
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#1_top-relative-expression-ranked_1000	LAMA2 PCSK5 TENM4 TENM3 LAMA1	4.79e-05	310	28	5	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k1_1000
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000	LAMA2 PCSK5 TENM4 TENM3 ITGB5 PCSK6 LAMA1	4.80e-05	768	28	7	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000	LAMA2 PCSK5 TENM4 TENM3 ITGB5 PCSK6 LAMA1	5.16e-05	777	28	7	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_1000
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000	LAMA2 PCSK5 TENM4 TENM3 ITGB5 PCSK6 LAMA1	5.88e-05	793	28	7	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#4_top-relative-expression-ranked_500	TENM4 TENM2 MEGF10	8.11e-05	64	28	3	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_500_k4
CoexpressionAtlas	FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#2	VWF MEGF6 MAMDC4 PCSK6	1.44e-04	205	28	4	Facebase_RNAseq_e10.5_Mandibular Arch_2500_K2
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_k-means-cluster#4_top-relative-expression-ranked_200	BCL6 TENM2	1.99e-04	16	28	2	gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_200_k4
CoexpressionAtlas	FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#1	VWF MEGF6 MAMDC4 PCSK6	2.16e-04	228	28	4	Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_2500_K1
CoexpressionAtlas	Stromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4	LAMA2 BMP1 TENM3 ITGB5 PCSK6	2.40e-04	437	28	5	GSM777046_500
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#1_top-relative-expression-ranked_1000	BMP1 TENM4 TENM3 LAMA1	2.63e-04	240	28	4	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k1_1000
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#2_top-relative-expression-ranked_1000	BMP1 TENM4 TENM3 LAMA1	3.83e-04	265	28	4	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k2_1000
CoexpressionAtlas	Progenitor-Cell-Biology-Consortium_inducedDefinitiveEndoderm_fromFibroblast-derived-iPSC_top-relative-expression-ranked_500	KCP VWF TENM4 MEGF10 LAMA1	4.14e-04	492	28	5	PCBC_DE_fibroblast_500
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000	LAMA2 TENM4 TENM3 ITGB5 PCSK6 LAMA1	4.33e-04	773	28	6	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#1_top-relative-expression-ranked_1000	TENM4 TENM2 MEGF10	5.20e-04	120	28	3	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k1
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	BMP1 TENM4 CFI TENM3 ITGB5 MEGF10	6.55e-09	197	33	6	2ca5ebb708935a90b12b8e98a22ae2d664ed002e
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-6\|TCGA-Skin / Sample_Type by Project: Shred V9	KRTAP29-1 KRTAP4-9 KRTAP4-1 KRTAP4-8 KRTAP17-1	7.41e-08	146	33	5	522c32103c24fc26836bb5b642083904682d9292
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_3\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	KCP POMZP3 MEGF6 EHMT2 ITGB5	1.99e-07	178	33	5	9d575902d3dbe33437c9d4200df093a741269803
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 KCP BMP1 MEGF10 PCSK6	3.37e-07	198	33	5	5e70246a9ce199cb2fb5379912b8ab59456219e4
ToppCell	facs-Trachea-nan-3m-Mesenchymal-fibroblast\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 PCSK5 BMP1 ITGB5 PCSK6	3.37e-07	198	33	5	0dc7d59a07428a7b7e8bdc81f0e2417dd4ce3cf2
ToppCell	droplet-Tongue-Unstain-18m-Epithelial-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRTAP4-7 KRTAP4-9 KRTAP4-1 KRTAP4-8	2.79e-06	133	33	4	f7d0763b5eec2db33044d6850fd57462494038c1
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK5 KRTAP4-9 MEGF6 TENM2	5.53e-06	158	33	4	f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK5 KRTAP4-9 MEGF6 TENM2	5.53e-06	158	33	4	8c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 KCP LRP1B LAMA1	5.82e-06	160	33	4	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 KCP LRP1B LAMA1	5.82e-06	160	33	4	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	356C-Fibroblasts-Fibroblast-D-\|356C / Donor, Lineage, Cell class and subclass (all cells)	LAMA2 TENM3 PCSK6 LAMA1	6.73e-06	166	33	4	7c2eee0a4f45795a956acf936b85bdb35f1b1624
ToppCell	356C-Fibroblasts-Fibroblast-D\|356C / Donor, Lineage, Cell class and subclass (all cells)	LAMA2 TENM3 PCSK6 LAMA1	6.73e-06	166	33	4	7286a37b2827f3747469ffd0d76cbe81116db7ee
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EHMT2 KIAA0232 MEGF10 LAMA1	7.92e-06	173	33	4	23e50492bc673aff9df95d97f0b9be4ce57cbf01
ToppCell	facs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 BMP1 TENM4 PCSK6	8.47e-06	176	33	4	f25251abd4ef9fb077a978f9f9f658af58e4e0d2
ToppCell	facs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 BMP1 TENM4 PCSK6	8.47e-06	176	33	4	fee4e0f32aaf77294040c7af6c1f503571750d43
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_3\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	KCP POMZP3 MEGF6 EHMT2	8.67e-06	177	33	4	eb0cfe8e9a91910f9979608ed47add48d98ce4dd
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_3\|368C / Donor, Lineage, Cell class and subclass (all cells)	KCP POMZP3 EHMT2 ITGB5	8.86e-06	178	33	4	536a601abcc60867949ea06e9aafb6c7b799b56b
ToppCell	5'-Adult-Appendix-Neuronal-Glial_mature\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TENM4 MEGF6 TENM3 MEGF10	9.46e-06	181	33	4	3aa81ac64d0cc9a74fbfa71e2176740548e7cd06
ToppCell	5'-Adult-Appendix-Neuronal-Glial_mature-Adult_Glia\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TENM4 MEGF6 TENM3 MEGF10	9.46e-06	181	33	4	997ba1be2824b00d684f2163d0114656ed11fa53
ToppCell	5'-Adult-Appendix-Neuronal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TENM4 MEGF6 TENM3 MEGF10	9.46e-06	181	33	4	e6b7e8dd5c13cc10ba22f2f5a8c669486f934bdc
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF MEGF6 CFI MAMDC4	9.88e-06	183	33	4	b0b5a41f1a40f9c946d0dc8b67eaccdd9f9b73a5
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 KCP TENM3 ITGB5	1.05e-05	186	33	4	96f6603cc75fa1ffc2a2fdb94ec0ec09498e540a
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 KCP TENM3 ITGB5	1.08e-05	187	33	4	85f1678338a47d91e296f0620d4887f057eb7e70
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 BMP1 ITGB5 PCSK6	1.10e-05	188	33	4	7191087d8754f5e8700e3d744cd920ee26db1e57
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TENM4 LRP1B MEGF11 LAMA1	1.15e-05	190	33	4	bf4511395fa97efd1c1cd17cc9bebb0271ee7f0e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TENM4 LRP1B MEGF11 LAMA1	1.15e-05	190	33	4	b6b8964b4910083499681b5fdf554e127b6a4c4e
ToppCell	COVID-19-kidney-TAL\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TENM4 LRP1B MEGF11 LAMA1	1.17e-05	191	33	4	fe55475ce0666ab5122447a813dc2369e24947b8
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KCP TENM4 MEGF11 LAMA1	1.17e-05	191	33	4	9032aa974aa1b7b1095b8d1b58dcb087358a5001
ToppCell	facs-Heart-LV-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 KCP ITGB5 PCSK6	1.17e-05	191	33	4	b7a57691a4742070cee640e285c1f4d0da95baf1
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TENM4 LRP1B MEGF11 LAMA1	1.17e-05	191	33	4	2fa1b9e76a0ed2d2f0de74349e266cf4a5f51aad
ToppCell	COVID-19-kidney-Mito-rich_Distal\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TENM4 LRP1B MEGF11 LAMA1	1.17e-05	191	33	4	0965f621ebcd92ccdeb21cc27022180ce3cfe910
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KCP TENM4 MEGF11 LAMA1	1.17e-05	191	33	4	5717809a1476c20f65bce722c5a57cff92ee0d7a
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	LAMA2 PCSK5 VWF TENM4	1.19e-05	192	33	4	60b1312e84f6d6448365a952469c506c00b5fe93
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 KCP BMP1 PCSK6	1.19e-05	192	33	4	671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_2-SCMF\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	LAMA2 TENM4 ITGB5 MEGF10	1.19e-05	192	33	4	67e845e513e76e820f55e2f0d15eb16f2944d05c
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 KCP BMP1 PCSK6	1.19e-05	192	33	4	840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	TENM4 TENM3 LRP1B TENM2	1.19e-05	192	33	4	d0649410cf5eacdb0c1dce70e37c7473ef5fddfa
ToppCell	Control-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	PCSK5 VWF LRP1B ITGB5	1.19e-05	192	33	4	7e89b9125e8b85f6be85eeccef5c8644647ab0e1
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 BMP1 ITGB5 PCSK6	1.19e-05	192	33	4	beac6b3c191b11add8e39e8d04562b478ea8929e
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LAMA2 TENM4 ADAM21 TENM2	1.22e-05	193	33	4	549a0b750c860b615aff767ad04c9a9d20f802f0
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 BMP1 ITGB5 PCSK6	1.22e-05	193	33	4	eff718664fe0aaf89050efd9cc7b6dfb1df46666
ToppCell	facs-MAT-Fat-3m-Mesenchymal-mesenchymal_progenitor\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 PCSK5 BMP1 ITGB5	1.22e-05	193	33	4	85faf6c5ce4769615a4eca036e2ba307e176bb52
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 BMP1 ITGB5 PCSK6	1.22e-05	193	33	4	49600db68ed65cafc67bd45a285b364e4f5f88af
ToppCell	facs-MAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 PCSK5 BMP1 ITGB5	1.22e-05	193	33	4	f95b95c58a6edb8a03dd15ae166f47f9f33d8bd6
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 KCP TENM3 ITGB5	1.22e-05	193	33	4	e74fdc8718fe0933e1f4dd3fe37e2134983b99b6
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 KCP TENM3 ITGB5	1.22e-05	193	33	4	658c2b30a4d806c5ce78ea4392fe8eb86b8d1e99
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Mesenchymal-mesenchymal_stem_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 BMP1 ITGB5 PCSK6	1.22e-05	193	33	4	160691b671710be10220803d788c2c961c236af1
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 BMP1 ITGB5 PCSK6	1.22e-05	193	33	4	428b1a3ad87dff7f65de5161d40f102572a9341b
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 BMP1 ITGB5 PCSK6	1.22e-05	193	33	4	45b5cab4dfeb0ed3b13631db5963740a792b810f
ToppCell	facs-MAT-Fat-3m-Mesenchymal\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 PCSK5 BMP1 ITGB5	1.22e-05	193	33	4	110a7d2ba7d066c2be38be98b643b76c520dd980
ToppCell	facs-Heart-RA-18m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 TENM3 ITGB5 PCSK6	1.24e-05	194	33	4	bc945450b350f597c3ff910d3a14a533d90086a8
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 KCP TENM3 ITGB5	1.24e-05	194	33	4	1bcb3fafd498614f7bac2b1c9b7de56e39110f65
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 KCP TENM3 ITGB5	1.24e-05	194	33	4	83863da11dfbe59b2d0a2c08db40b537c150588c
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	TENM4 CFI TENM3 LRP1B	1.24e-05	194	33	4	85e00861c5068a27d0cf0ae677f420c8245baa9a
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LAMA2 PCSK5 TENM4 MEGF10	1.27e-05	195	33	4	b0d408f8bc1701a87596ed55efcd90749fee33e6
ToppCell	facs-Heart-RA-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 TENM3 ITGB5 PCSK6	1.27e-05	195	33	4	690d6e15d7c863fc8f2d33b1f7bf86f019f415c9
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LAMA2 PCSK5 TENM4 MEGF10	1.27e-05	195	33	4	a486a7acea0e91048cc48afa0dbd3926d30bc217
ToppCell	facs-Heart-RA-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 TENM3 ITGB5 PCSK6	1.27e-05	195	33	4	5c05e2bcea3d5d7ebe6325f7187ccf83301053d8
ToppCell	facs-Lung-nan\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 BMP1 ITGB5 PCSK6	1.29e-05	196	33	4	b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCell	facs-Lung-nan-3m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 BMP1 ITGB5 PCSK6	1.29e-05	196	33	4	787c6cd92035e0b1108c2c086c42a229016e476b
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-tRG-25\|World / Primary Cells by Cluster	ITGB5 MEGF10 PCSK6 LAMA1	1.32e-05	197	33	4	9d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-tRG\|World / Primary Cells by Cluster	ITGB5 MEGF10 PCSK6 LAMA1	1.32e-05	197	33	4	61749ccafeb938c310cff1de5ff924a1c794325a
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-ADGRG6-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PCSK5 KCP TENM3 ITGB5	1.40e-05	200	33	4	a9cdddc4e985dae59521e557479c24fcc2ac727d
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PCSK5 KCP TENM3 ITGB5	1.40e-05	200	33	4	347a510755374c6a66acee326565dfc447993f18
ToppCell	10x5'v1-week_14-16-Mesenchymal_osteo-stroma-early_osteoblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	BMP1 TENM3 ITGB5 MEGF10	1.40e-05	200	33	4	16a7c398626b6e82b394eb3ef013bda3a788659d
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-ADGRG6--L3-5\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PCSK5 KCP TENM3 ITGB5	1.40e-05	200	33	4	33b9199e0dfc267e2cea20b82d1c167f8adcc635
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-ADGRG6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PCSK5 KCP TENM3 ITGB5	1.40e-05	200	33	4	9719fabddc34051949468a7520289e3c750de4f8
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Vwf_(Vwf)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	KCP VWF CFI	3.65e-05	87	33	3	cc89f4176b70d4eb5b5bf0ff2319b5f1f9e292c0
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Vwf_(Vwf)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	KCP VWF CFI	3.65e-05	87	33	3	4274e04fa4aca85c2cefd8c5e03d0fa4a4f15536
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	KCP VWF CFI	3.65e-05	87	33	3	54cbdf80aae3595eaace20c7cbac763282558213
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Vwf_(Vwf)--\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	KCP VWF CFI	3.65e-05	87	33	3	8b1a0bd5d6af32afaca19e9c69f86530bbaa309d
ToppCell	Striatum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)-\|Striatum / BrainAtlas - Mouse McCarroll V32	VWF CFI MAMDC4	4.60e-05	94	33	3	9d1dfd534871da30bc25a42e36bed9826f6127d8
ToppCell	Striatum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)--\|Striatum / BrainAtlas - Mouse McCarroll V32	VWF CFI MAMDC4	4.60e-05	94	33	3	858dda192747e71533736247bc9e135f763a8860
ToppCell	Striatum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)\|Striatum / BrainAtlas - Mouse McCarroll V32	VWF CFI MAMDC4	4.60e-05	94	33	3	901c4908d27a06c81853a02042cd331549e0e27d
ToppCell	PND01-03-samps-Mesenchymal-Myofibroblast-MyoFB-3\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	LAMA2 TENM3 TRIM42	1.35e-04	135	33	3	5b13ff740d9f7d96274aebb6b389a80f6004adc7
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_VISp_C1ql2_Cdh13\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PCSK5 BCL6 TENM3	1.38e-04	136	33	3	1f3000d5f105c87c80f8ae1dd2264bcd7f757a9c
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PCSK5 BCL6 TENM3	1.50e-04	140	33	3	7cc891d676555609add6fc7880735d948a2ad801
ToppCell	COVID-19-Heart-Adipocyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TENM4 TENM3 MEGF10	1.95e-04	153	33	3	93958bd9c951222ba5b740d1cb83fd5d78a10e1e
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Myocytic\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LAMA2 KCP ITGB5	2.07e-04	156	33	3	6365b69ede98bc866e996bc52736b00401aacf6f
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LAMA2 KCP ITGB5	2.11e-04	157	33	3	bfec34182f052cf1c0d847ba53ea335d4d1190de
ToppCell	droplet-Marrow-BM-30m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMP1 VWF KIAA0232	2.31e-04	162	33	3	75df7ff779a3b9159ba97d852da1f8df650b9ce5
ToppCell	368C-Fibroblasts-Fibroblast-E\|368C / Donor, Lineage, Cell class and subclass (all cells)	LAMA2 BMP1 ITGB5	2.31e-04	162	33	3	e17632778a57c71d6005d3abca3a0443a92040e7
ToppCell	368C-Fibroblasts-Fibroblast-E-\|368C / Donor, Lineage, Cell class and subclass (all cells)	LAMA2 BMP1 ITGB5	2.31e-04	162	33	3	ac4a80fd72c9311ea2b3e574c6284bbce4f2756c
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_STALK\|Cerebellum / BrainAtlas - Mouse McCarroll V32	KCP VWF MEGF6	2.44e-04	165	33	3	7d319a112b9062efee428bef6f4534d2ce782e04
ToppCell	facs-Heart-RV-24m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 PCSK6 LAMA1	2.52e-04	167	33	3	3e3d8f6df2feefafad5b44ba0ebf5b5a0fe4ed58
ToppCell	facs-Heart-RV-24m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA2 PCSK6 LAMA1	2.52e-04	167	33	3	3ad9f3122dbe96580f640388ef920ea209fc2349
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TENM3 MEGF10 LAMA1	2.57e-04	168	33	3	948d9e9972bd2a4b503d55fa69b70dd568a35a67
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-8\|TCGA-Liver / Sample_Type by Project: Shred V9	VWF CFI MAMDC4	2.71e-04	171	33	3	c4a919fe3d56ae6df2fcab6686abacc10befc053
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TENM4 MEGF6 TENM3	2.80e-04	173	33	3	30d67738633493d47f06ae452424382f069b6c0a
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMA2 TENM3 MEGF10	2.80e-04	173	33	3	922356a5b4c84607318ac24d7caa2e235b72b066
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCP BMP1 PCSK6	2.85e-04	174	33	3	68a6ed81e7e1f95b61f7ee20403980fa3a8db4d0
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TENM4 LRP1B LAMA1	2.90e-04	175	33	3	e5467dacf81f1f913b1719931cf1a7331434a7e7
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-stromal_related\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMA2 BCL6 MEGF6	2.90e-04	175	33	3	b8995e7ada85ba959f06264a0295b61e390c4e6c
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-stromal_related-T_reticular\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMA2 BCL6 MEGF6	2.90e-04	175	33	3	7ae76bd3b4f610b2f98716a4456437cd3696b686
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VWF MEGF6 EZH2	2.90e-04	175	33	3	d43ae33a6256606ce848247cad32d74f21b38988
ToppCell	COVID-19-Heart-CM_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	LAMA2 KCP TENM2	2.95e-04	176	33	3	9df7a124ebafb0087da0cda133a394275d7bed81
ToppCell	wk_15-18-Mesenchymal-Chondrocyte-Resting_chondrocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	TENM3 ITGB5 LAMA1	2.99e-04	177	33	3	b01d7a6a78169962123ddfb0bb588f51d138ad02
ToppCell	PBMC-Convalescent-Hematopoietic-Platelet-Platelet-plt_3\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	VWF ITGB5 PCSK6	3.04e-04	178	33	3	850fcd368c4478c57eaedc74544773ea220f41f3
ToppCell	RV-11._Adipocyte\|RV / Chamber and Cluster_Paper	PCSK5 TENM4 TENM3	3.04e-04	178	33	3	278bbea5cf8f0589f71675c7a3d00679391b5253
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KCP TENM4 LAMA1	3.04e-04	178	33	3	4df6218b20c2f076c22346d23260964cc0d73e65
Disease	B-cell lymphoma (is_implicated_in)	BCL6 EZH2	2.24e-05	7	31	2	DOID:707 (is_implicated_in)
Disease	diffuse large B-cell lymphoma (is_marker_for)	BCL6 EZH2	2.98e-05	8	31	2	DOID:0050745 (is_marker_for)
Disease	triacylglycerol 58:6 measurement	LRP1B TENM2	2.98e-05	8	31	2	EFO_0010440
Disease	adverse effect, response to xenobiotic stimulus	BCL6 LRP1B LAMA1	3.28e-05	59	31	3	EFO_0009658, GO_0009410
Disease	severe acute respiratory syndrome, COVID-19	MEGF6 LRP1B TENM2 MEGF11 PCSK6	9.58e-05	447	31	5	EFO_0000694, MONDO_0100096
Disease	Chromosome Breaks	EZH2 EHMT2	9.64e-05	14	31	2	C0333704
Disease	Chromosome Breakage	EZH2 EHMT2	9.64e-05	14	31	2	C0376628
Disease	Child Behaviour Checklist assessment	TENM4 TENM3	1.62e-04	18	31	2	EFO_0005661
Disease	Lymphoma, Follicular	BCL6 EZH2	2.01e-04	20	31	2	C0024301
Disease	sleep quality	LAMA2 TENM4 LRP1B	2.58e-04	118	31	3	EFO_0005272
Disease	Takayasu arteritis	PCSK5 EHMT2 LRP1B	5.01e-04	148	31	3	EFO_1001857
Disease	visceral heterotaxy (implicated_via_orthology)	PCSK5 MEGF8	6.95e-04	37	31	2	DOID:0050545 (implicated_via_orthology)
Disease	autoimmune disease	KCP BCL6 EHMT2	7.89e-04	173	31	3	EFO_0005140
Disease	interleukin 2 measurement	ITGB5 MEGF11	8.54e-04	41	31	2	EFO_0008331
Disease	rectum cancer	LRP1B MEGF10	8.96e-04	42	31	2	EFO_1000657

Protein segments in the cluster

Peptide	Gene	Start	Entry
CNFVCDCRDCSDEAQ	MAMDC4	36	Q6UXC1
DCGDQSDELCCKACQ	CFI	246	P05156
DCGSVQQCEQDACCL	ADAM21	421	Q9UKJ8
CVDDCSSSNCLCGQL	EHMT2	976	Q96KQ7
ECSKDNGGCQQDCVN	BMP1	706	P13497
NCSQECQCHNGGTCD	MEGF10	276	Q96KG7
NCSSRCGCKNDAVCS	MEGF10	451	Q96KG7
QDCAQLCSCANNGTC	MEGF11	661	A6BM72
GCQQLCECMNNSTCD	MEGF11	791	A6BM72
CADASDEKNCNNTDC	LRP1B	2616	Q9NZR2
NFCEKFCQCSSECQN	EZH2	541	Q15910
ECKACDSNCGSCDQN	PCSK5	1081	Q92824
CDENCLSCAGSSRNC	PCSK6	901	P29122
CEEEINNFCGCKAGC	KIAA0232	1236	Q92628
CSEAACGAADCEQCT	MEGF8	1991	Q7Z7M0
SDQGCDQGLCQETCC	KRTAP4-1	11	Q9BYQ7
RCECEHNTCGDSCDQ	LAMA2	306	P24043
GDCSCNQCSCFESEF	ITGB5	526	P18084
SSCENGAFFCNECDC	BCL6	511	P41182
SDQGCSQDLCQETCC	KRTAP4-7	11	Q9BYR0
SDQGCGQDLCQETCC	KRTAP4-8	11	Q9BYQ9
SDQGCGQDLCQETCC	KRTAP4-9	11	Q9BYQ8
GDCFTCCTQEQNCCE	KRTAP17-1	6	Q9BYP8
CQEKCCDASPCQQSS	KRTAP29-1	116	A8MX34
CRSACNCTAGAACDA	MEGF6	956	O75095
ANDPNCKCCCTASSN	TRIM42	71	Q8IWZ5
CSCQAGEVSCEEQEC	KCP	396	Q6ZWJ8
QCEHNTCGESCNRCC	LAMA1	291	P25391
AASDCDCKNDVNCNC	TENM2	1516	Q9NT68
CCNSDCTLKEGVQCS	ADAM17	501	P78536
TQCCDEYECACNCVN	VWF	2386	P04275
ECKCCNICGTSENDD	DPF2	326	Q92785
SGCDCKNDANCDCFS	TENM4	1511	Q6N022
SECDCKNDANCDCYQ	TENM3	1446	Q9P273
EGLADICQCCNKGDC	POMZP3	151	Q6PJE2