Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransporter activity

RHCG SLC37A1 CIDEB CACNA1D SCN11A SLC16A13 ABCA2 GJD2 SLC11A2 SLC16A9 SLC38A4 SLC2A7 SLC22A15 SLC2A14 SLC19A3 TCIRG1 SLCO1B3 GRIA3 SLCO1B1 AQP7 SLC7A14 MFSD12 SLC2A3 SLC30A7 SLC7A8 CNNM3 GJA5 SLC35A3 P2RX7 SLC22A16 KCND1 KCND2 KCND3 SLC19A1 SLC2A6 KCNK15 NPC1L1 ABCB11 KCNS1 ATP12A SLC26A11 SLC25A28 SLC2A12 SLC16A7 M6PR SLC38A3 SLC25A31

6.73e-22128914047GO:0005215
GeneOntologyMolecularFunctiontransmembrane transporter activity

RHCG SLC37A1 CACNA1D SCN11A SLC16A13 ABCA2 GJD2 SLC11A2 SLC16A9 SLC38A4 SLC2A7 SLC22A15 SLC2A14 SLC19A3 TCIRG1 SLCO1B3 GRIA3 SLCO1B1 AQP7 SLC7A14 MFSD12 SLC2A3 SLC30A7 SLC7A8 CNNM3 GJA5 SLC35A3 P2RX7 SLC22A16 KCND1 KCND2 KCND3 SLC19A1 SLC2A6 KCNK15 ABCB11 KCNS1 ATP12A SLC26A11 SLC25A28 SLC2A12 SLC16A7 SLC38A3 SLC25A31

8.52e-21118014044GO:0022857
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC37A1 SLC16A13 SLC16A9 SLC38A4 SLC2A14 SLC19A3 SLCO1B3 GRIA3 SLCO1B1 SLC7A14 MFSD12 SLC2A3 SLC7A8 SLC35A3 SLC19A1 SLC2A6 ABCB11 SLC26A11 SLC16A7 SLC38A3 SLC25A31

1.51e-1529314021GO:0008514
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC37A1 SLC16A13 ABCA2 SLC11A2 SLC16A9 SLC38A4 TCIRG1 SLCO1B3 SLCO1B1 MFSD12 SLC7A8 SLC35A3 SLC19A1 ABCB11 ATP12A SLC26A11 SLC2A12 SLC16A7 SLC38A3 SLC25A31

1.45e-1047714020GO:0022804
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC16A13 SLC16A9 SLC38A4 SLC19A3 SLCO1B3 GRIA3 SLCO1B1 SLC7A14 MFSD12 SLC7A8 SLC19A1 ABCB11 SLC16A7 SLC38A3

2.20e-1020714014GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC16A13 SLC16A9 SLC38A4 SLC19A3 SLCO1B3 GRIA3 SLCO1B1 SLC7A14 MFSD12 SLC7A8 SLC19A1 ABCB11 SLC16A7 SLC38A3

2.35e-1020814014GO:0005342
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC37A1 SLC16A13 SLC11A2 SLC16A9 SLC38A4 SLCO1B3 SLCO1B1 MFSD12 SLC7A8 SLC35A3 SLC19A1 SLC26A11 SLC2A12 SLC16A7 SLC38A3 SLC25A31

2.97e-1029614016GO:0015291
GeneOntologyMolecularFunctioncarbohydrate transmembrane transporter activity

SLC2A7 SLC2A14 AQP7 SLC2A3 SLC2A6 ABCB11 SLC2A12

1.57e-08421407GO:0015144
GeneOntologyMolecularFunctionorganic cation transmembrane transporter activity

SLC16A9 SLC38A4 SLC22A15 SLC19A3 MFSD12 SLC7A8 SLC22A16 SLC38A3

1.21e-07831408GO:0015101
GeneOntologyMolecularFunctionamide transmembrane transporter activity

SLC19A3 SLCO1B3 SLCO1B1 AQP7 SLC19A1 SLC38A3

4.55e-07421406GO:0042887
GeneOntologyMolecularFunctionhexose transmembrane transporter activity

SLC2A7 SLC2A14 SLC2A3 SLC2A6 SLC2A12

7.48e-07251405GO:0015149
GeneOntologyMolecularFunctionD-glucose transmembrane transporter activity

SLC2A7 SLC2A14 SLC2A3 SLC2A6 SLC2A12

7.48e-07251405GO:0055056
GeneOntologyMolecularFunctionmonosaccharide transmembrane transporter activity

SLC2A7 SLC2A14 SLC2A3 SLC2A6 SLC2A12

1.12e-06271405GO:0015145
GeneOntologyMolecularFunctionA-type (transient outward) potassium channel activity

KCND1 KCND2 KCND3

1.34e-0641403GO:0005250
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

RHCG SLC37A1 CACNA1D SCN11A SLC11A2 SLC38A4 TCIRG1 GRIA3 AQP7 SLC30A7 KCND1 KCND2 KCND3 KCNK15 KCNS1 ATP12A SLC26A11 SLC25A28 SLC38A3

1.49e-0675814019GO:0015318
GeneOntologyMolecularFunctionsugar transmembrane transporter activity

SLC2A7 SLC2A14 SLC2A3 SLC2A6 SLC2A12

1.64e-06291405GO:0051119
GeneOntologyMolecularFunctionmodified amino acid transmembrane transporter activity

SLC16A9 SLC22A15 SLC19A3 SLC22A16 SLC19A1

3.20e-06331405GO:0072349
GeneOntologyMolecularFunctionmonocarboxylic acid transmembrane transporter activity

SLC16A13 SLC16A9 SLCO1B3 SLCO1B1 SLC7A14 ABCB11 SLC16A7

3.30e-06901407GO:0008028
GeneOntologyMolecularFunctionvitamin transmembrane transporter activity

SLC2A14 SLC19A3 SLC2A3 SLC19A1 SLC2A6

4.99e-06361405GO:0090482
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

CACNA1D SCN11A SLC11A2 SLC38A4 GRIA3 SLC30A7 KCND1 KCND2 KCND3 KCNK15 KCNS1 ATP12A SLC25A28 SLC38A3

5.09e-0646514014GO:0046873
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

RHCG CACNA1D SCN11A SLC11A2 SLC38A4 TCIRG1 GRIA3 SLC30A7 KCND1 KCND2 KCND3 KCNK15 KCNS1 ATP12A SLC25A28 SLC38A3

8.56e-0662714016GO:0022890
GeneOntologyMolecularFunctionmicrotubule motor activity

KIF27 CENPE KIF21A KIF4A KIF2A DNAH11

9.67e-06701406GO:0003777
GeneOntologyMolecularFunctionsymporter activity

SLC16A13 SLC11A2 SLC16A9 SLC38A4 MFSD12 SLC2A12 SLC16A7 SLC38A3

1.09e-051501408GO:0015293
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

CACNA1D SCN11A SLC11A2 SLC38A4 TCIRG1 GRIA3 SLC30A7 P2RX7 KCND1 KCND2 KCND3 SLC19A1 KCNK15 KCNS1 ATP12A SLC26A11 SLC25A28 SLC38A3

1.12e-0579314018GO:0015075
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

CACNA1D SCN11A SLC11A2 SLC38A4 TCIRG1 GRIA3 SLC30A7 P2RX7 KCND1 KCND2 KCND3 KCNK15 KCNS1 ATP12A SLC25A28 SLC38A3

1.74e-0566414016GO:0008324
GeneOntologyMolecularFunctiondehydroascorbic acid transmembrane transporter activity

SLC2A14 SLC2A3 SLC2A6

1.84e-0581403GO:0033300
GeneOntologyMolecularFunctionchannel activity

RHCG CACNA1D SCN11A GJD2 GRIA3 AQP7 GJA5 P2RX7 KCND1 KCND2 KCND3 KCNK15 KCNS1 SLC26A11

1.99e-0552514014GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

RHCG CACNA1D SCN11A GJD2 GRIA3 AQP7 GJA5 P2RX7 KCND1 KCND2 KCND3 KCNK15 KCNS1 SLC26A11

2.04e-0552614014GO:0022803
GeneOntologyMolecularFunctionfructose transmembrane transporter activity

SLC2A7 SLC2A3 SLC2A6

2.75e-0591403GO:0005353
GeneOntologyMolecularFunctionoutward rectifier potassium channel activity

KCND1 KCND2 KCND3 KCNK15

3.58e-05271404GO:0015271
GeneOntologyMolecularFunctionxylose binding

SLC2A14 SLC2A3

4.88e-0521402GO:0033222
GeneOntologyMolecularFunctionantiporter activity

SLC37A1 SLC7A8 SLC35A3 SLC19A1 SLC26A11 SLC38A3 SLC25A31

5.41e-051381407GO:0015297
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

SLC38A4 GRIA3 SLC7A14 MFSD12 SLC7A8 SLC38A3

9.72e-051051406GO:0015171
GeneOntologyMolecularFunctionD-glucose binding

SLC2A14 SLC2A3 UGP2

1.16e-04141403GO:0005536
GeneOntologyMolecularFunctionorganic hydroxy compound transmembrane transporter activity

SLCO1B3 SLCO1B1 AQP7 ABCB11 SLC16A7

1.32e-04701405GO:1901618
GeneOntologyMolecularFunctionquaternary ammonium group transmembrane transporter activity

SLC16A9 SLC22A15 SLC22A16

1.44e-04151403GO:0015651
GeneOntologyMolecularFunctionN-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity

GCNT2 GCNT4

1.46e-0431402GO:0008109
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

STAB2 LRP1 SORL1

1.77e-04161403GO:0005041
GeneOntologyMolecularFunctionalanine transmembrane transporter activity

SLC38A4 SLC7A8 SLC38A3

1.77e-04161403GO:0022858
GeneOntologyMolecularFunctioncytoskeletal motor activity

KIF27 CENPE KIF21A KIF4A KIF2A DNAH11

1.85e-041181406GO:0003774
GeneOntologyMolecularFunctionneutral L-amino acid transmembrane transporter activity

SLC38A4 MFSD12 SLC7A8 SLC38A3

1.92e-04411404GO:0015175
GeneOntologyMolecularFunctionATP-dependent activity

ABCA2 KIF27 CENPE KIF21A TCIRG1 KIF4A FBH1 ABCB11 KIF2A ATP12A HSP90AA4P HSP90AA2P DNAH11

3.91e-0461414013GO:0140657
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

STAB2 LRP1 SORL1

4.09e-04211403GO:0030228
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

CACNA1D KCND1 KCND2 KCND3 KCNK15 KCNS1

7.16e-041521406GO:0022843
GeneOntologyMolecularFunctionmonoatomic cation channel activity

CACNA1D SCN11A GRIA3 P2RX7 KCND1 KCND2 KCND3 KCNK15 KCNS1

7.16e-043431409GO:0005261
GeneOntologyMolecularFunctioncarnitine transmembrane transporter activity

SLC16A9 SLC22A16

7.19e-0461402GO:0015226
GeneOntologyMolecularFunctiongalactose transmembrane transporter activity

SLC2A14 SLC2A3

7.19e-0461402GO:0005354
GeneOntologyMolecularFunctionfolic acid transmembrane transporter activity

SLC19A3 SLC19A1

7.19e-0461402GO:0008517
GeneOntologyMolecularFunctionferrous iron transmembrane transporter activity

SLC11A2 SLC25A28

7.19e-0461402GO:0015093
GeneOntologyMolecularFunctionvoltage-gated potassium channel activity

KCND1 KCND2 KCND3 KCNK15 KCNS1

7.62e-041021405GO:0005249
GeneOntologyMolecularFunctioncarbohydrate derivative transmembrane transporter activity

SLC37A1 SLC35A3 SLC19A1 SLC25A31

7.81e-04591404GO:1901505
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCA2 KIF27 KIF21A FBH1 ABCB11 KIF2A ATP12A HSP90AA4P HSP90AA2P DNAH11

1.11e-0344114010GO:0016887
GeneOntologyMolecularFunctionpotassium ion transmembrane transporter activity

KCND1 KCND2 KCND3 KCNK15 KCNS1 ATP12A

1.17e-031671406GO:0015079
GeneOntologyMolecularFunctionneutral L-amino acid:sodium symporter activity

SLC38A4 SLC38A3

1.33e-0381402GO:0005295
GeneOntologyMolecularFunctionmonoatomic ion channel activity

CACNA1D SCN11A GRIA3 P2RX7 KCND1 KCND2 KCND3 KCNK15 KCNS1 SLC26A11

1.50e-0345914010GO:0005216
GeneOntologyMolecularFunctionthyroid hormone transmembrane transporter activity

SLCO1B1 SLC7A8

1.70e-0391402GO:0015349
GeneOntologyMolecularFunctionamine transmembrane transporter activity

SLC7A8 SLC22A16

1.70e-0391402GO:0005275
GeneOntologyMolecularFunctionL-alanine transmembrane transporter activity

SLC7A8 SLC38A3

1.70e-0391402GO:0015180
GeneOntologyMolecularFunctiongalactoside binding

SLC2A14 SLC2A3

1.70e-0391402GO:0016936
GeneOntologyMolecularFunctionbile acid transmembrane transporter activity

SLCO1B3 SLCO1B1 ABCB11

1.72e-03341403GO:0015125
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

CACNA1D KCND1 KCND2 KCND3 KCNK15 KCNS1

1.81e-031821406GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

CACNA1D KCND1 KCND2 KCND3 KCNK15 KCNS1

1.91e-031841406GO:0022832
GeneOntologyMolecularFunctionpotassium channel activity

KCND1 KCND2 KCND3 KCNK15 KCNS1

2.09e-031281405GO:0005267
GeneOntologyMolecularFunctionretromer complex binding

SLC11A2 M6PR

2.12e-03101402GO:1905394
GeneOntologyMolecularFunctiongated channel activity

CACNA1D GRIA3 P2RX7 KCND1 KCND2 KCND3 KCNK15 KCNS1

2.49e-033341408GO:0022836
GeneOntologyMolecularFunctiondisordered domain specific binding

GJA5 HSP90AA4P HSP90AA2P

2.56e-03391403GO:0097718
GeneOntologyMolecularFunctionorganophosphate ester transmembrane transporter activity

SLC37A1 SLC19A1 SLC25A31

2.56e-03391403GO:0015605
GeneOntologyMolecularFunctionstructural constituent of myelin sheath

GPM6B PLP1

2.58e-03111402GO:0019911
GeneOntologyMolecularFunctioniron ion transmembrane transporter activity

SLC11A2 SLC25A28

2.58e-03111402GO:0005381
GeneOntologyMolecularFunctionlipid transporter activity

CIDEB ABCA2 SLCO1B3 SLCO1B1 NPC1L1 ABCB11

2.62e-031961406GO:0005319
GeneOntologyMolecularFunctiontransition metal ion transmembrane transporter activity

SLC11A2 SLC30A7 SLC25A28

3.62e-03441403GO:0046915
GeneOntologyMolecularFunctionazole transmembrane transporter activity

SLC19A3 SLC38A3

4.20e-03141402GO:1901474
GeneOntologyMolecularFunctionprostaglandin transmembrane transporter activity

SLCO1B3 SLCO1B1

4.20e-03141402GO:0015132
GeneOntologyMolecularFunctionalpha-mannosidase activity

MAN2B2 MANEA

4.83e-03151402GO:0004559
GeneOntologyMolecularFunctionicosanoid transmembrane transporter activity

SLCO1B3 SLCO1B1

4.83e-03151402GO:0071714
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC11A2 SLC38A4 TCIRG1 SLC19A1 ATP12A SLC26A11 SLC38A3

5.39e-033011407GO:0022853
GeneOntologyMolecularFunctionoligopeptide transmembrane transporter activity

SLCO1B3 SLCO1B1

5.49e-03161402GO:0035673
GeneOntologyMolecularFunctionmannosidase activity

MAN2B2 MANEA

5.49e-03161402GO:0015923
GeneOntologyMolecularFunctionsodium-independent organic anion transmembrane transporter activity

SLCO1B3 SLCO1B1

6.94e-03181402GO:0015347
GeneOntologyMolecularFunctionlow-density lipoprotein particle binding

STAB2 SORL1

6.94e-03181402GO:0030169
GeneOntologyBiologicalProcessorganic anion transport

SLC37A1 SLC16A13 SLC16A9 SLC38A4 SLC2A14 SLC19A3 SLCO1B3 SLCO1B1 SLC7A14 MFSD12 SLC2A3 SLC7A8 SLC35A3 P2RX7 SLC19A1 SLC2A6 ABCB11 SLC26A11 SLC16A7 SLC38A3 SLC25A31

3.37e-1151513821GO:0015711
GeneOntologyBiologicalProcesscarboxylic acid transport

SLC16A13 SLC16A9 SLC38A4 SLC19A3 SLCO1B3 SLCO1B1 SLC7A14 MFSD12 SLC7A8 P2RX7 SLC19A1 ABCB11 SLC26A11 SLC16A7 SLC38A3

1.09e-0741013815GO:0046942
GeneOntologyBiologicalProcessorganic acid transport

SLC16A13 SLC16A9 SLC38A4 SLC19A3 SLCO1B3 SLCO1B1 SLC7A14 MFSD12 SLC7A8 P2RX7 SLC19A1 ABCB11 SLC26A11 SLC16A7 SLC38A3

1.16e-0741213815GO:0015849
GeneOntologyBiologicalProcesscarbohydrate transport

SLC37A1 SLC2A7 SLC2A14 AQP7 MFSD12 SLC2A3 SLC35A3 SLC2A6 ABCB11 SLC2A12

5.09e-0718613810GO:0008643
GeneOntologyBiologicalProcessaction potential

CACNA1D SCN11A GJD2 GJA5 P2RX7 KCND1 KCND2 KCND3 KCNS1 CNR2

1.03e-0620113810GO:0001508
GeneOntologyBiologicalProcesstransport across blood-brain barrier

ABCA2 SLC2A3 SLC7A8 SLC19A1 LRP1 SLC16A7 SLC38A3

1.93e-06871387GO:0150104
GeneOntologyBiologicalProcessvitamin transport

SLC2A14 SLC19A3 SLC2A3 SLC19A1 SLC2A6 NPC1L1

1.98e-06561386GO:0051180
GeneOntologyBiologicalProcessvascular transport

ABCA2 SLC2A3 SLC7A8 SLC19A1 LRP1 SLC16A7 SLC38A3

2.08e-06881387GO:0010232
GeneOntologyBiologicalProcessmonoatomic ion transport

CACNA1D SCN11A SLC11A2 SLC38A4 SLC22A15 TCIRG1 SLCO1B3 GRIA3 SLCO1B1 SLC30A7 CNNM3 GJA5 P2RX7 SLC22A16 KCND1 KCND2 KCND3 SLC19A1 KCNK15 KCNS1 ATP12A SLC26A11 SLC25A28 PLP1 SLC38A3

4.20e-06137413825GO:0006811
GeneOntologyBiologicalProcesssphingosine metabolic process

ABCA2 ASAH2 SPTLC1 PLPP2

1.05e-05211384GO:0006670
GeneOntologyBiologicalProcessmodified amino acid transport

SLC16A9 SLC22A15 SLC19A3 SLC22A16 SLC19A1

1.10e-05441385GO:0072337
GeneOntologyBiologicalProcesssphingoid metabolic process

ABCA2 ASAH2 SPTLC1 PLPP2

1.54e-05231384GO:0046519
GeneOntologyBiologicalProcessdehydroascorbic acid transport

SLC2A14 SLC2A3 SLC2A6

2.39e-0591383GO:0070837
GeneOntologyBiologicalProcessimport across plasma membrane

CACNA1D SLC11A2 SLC38A4 SLC2A3 SLC7A8 KCND3 SLC19A1 ATP12A SLC38A3

2.51e-052301389GO:0098739
GeneOntologyBiologicalProcessfructose transmembrane transport

SLC2A7 SLC2A3 SLC2A6

3.40e-05101383GO:0015755
GeneOntologyBiologicalProcessL-alanine transport

SLC38A4 SLC7A8 SLC38A3

4.65e-05111383GO:0015808
GeneOntologyBiologicalProcessorganic cation transport

SLC16A9 SLC38A4 SLC19A3 MFSD12 SLC7A8 SLC22A16 SLC38A3

5.52e-051451387GO:0015695
GeneOntologyBiologicalProcessdiol metabolic process

ABCA2 ASAH2 SPTLC1 PLPP2

7.61e-05341384GO:0034311
GeneOntologyBiologicalProcessimport into cell

GPM6B CACNA1D ABCA2 STAB2 SLC11A2 TM9SF4 SLC38A4 SLC2A3 SLC7A8 P2RX7 LMBR1L KCND3 SLC19A1 LRP1 RAB39A ATP12A M6PR SLC38A3 SORL1

9.96e-05107413819GO:0098657
GeneOntologyBiologicalProcessamino-acid betaine transport

SLC16A9 SLC22A15 SLC22A16

1.01e-04141383GO:0015838
GeneOntologyBiologicalProcessceramide metabolic process

ABCA2 ASAH2 SPTLC1 P2RX7 PLPP2 CERS4

1.13e-041131386GO:0006672
GeneOntologyBiologicalProcesscarboxylic acid transmembrane transport

SLC16A9 SLC38A4 MFSD12 SLC7A8 SLC19A1 SLC16A7 SLC38A3

1.15e-041631387GO:1905039
GeneOntologyBiologicalProcessamide transport

CACNA1D ABCA2 SLC19A3 TCIRG1 SLCO1B3 SSTR5 SLCO1B1 AQP7 SLC19A1 LRP1 SLC38A3

1.24e-0442013811GO:0042886
GeneOntologyBiologicalProcesssphingosine biosynthetic process

ABCA2 ASAH2 SPTLC1

1.26e-04151383GO:0046512
GeneOntologyBiologicalProcesssphingoid biosynthetic process

ABCA2 ASAH2 SPTLC1

1.26e-04151383GO:0046520
GeneOntologyBiologicalProcessorganic acid transmembrane transport

SLC16A9 SLC38A4 MFSD12 SLC7A8 SLC19A1 SLC16A7 SLC38A3

1.34e-041671387GO:1903825
GeneOntologyBiologicalProcesscarbohydrate transmembrane transport

SLC2A7 SLC2A14 AQP7 SLC2A3 SLC2A6 ABCB11 SLC2A12

1.39e-041681387GO:0034219
GeneOntologyBiologicalProcessorganic hydroxy compound transport

GPM6B ABCA2 SLC19A3 SLCO1B3 SLCO1B1 AQP7 NPC1L1 LRP1 ABCB11 SLC16A7

1.51e-0435813810GO:0015850
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

RHCG SLC37A1 CACNA1D SCN11A SLC11A2 SLC38A4 TCIRG1 SLC30A7 P2RX7 KCND1 KCND2 KCND3 KCNK15 KCNS1 ATP12A SLC26A11 SLC25A28 PLP1

1.53e-04101713818GO:0098660
GeneOntologyBiologicalProcesssphingolipid metabolic process

ABCA2 ASAH2 SPTLC1 P2RX7 PLPP2 M6PR CERS4

1.85e-041761387GO:0006665
GeneOntologyBiologicalProcessalanine transport

SLC38A4 SLC7A8 SLC38A3

2.22e-04181383GO:0032328
GeneOntologyBiologicalProcessquaternary ammonium group transport

SLC16A9 SLC22A15 SLC22A16

2.63e-04191383GO:0015697
GeneOntologyBiologicalProcessL-alanine import across plasma membrane

SLC38A4 SLC7A8

2.64e-0441382GO:1904273
GeneOntologyBiologicalProcessprotein K27-linked deubiquitination

YOD1 USP15

2.64e-0441382GO:1990167
GeneOntologyBiologicalProcesscardiac muscle cell action potential

CACNA1D SCN11A GJA5 KCND2 KCND3

2.97e-04871385GO:0086001
GeneOntologyBiologicalProcessamino acid transport

SLC38A4 SLC22A15 SLC7A14 MFSD12 SLC7A8 P2RX7 SLC38A3

3.46e-041951387GO:0006865
GeneOntologyBiologicalProcessprotein exit from endoplasmic reticulum

TM9SF4 HM13 YOD1 SORL1

3.76e-04511384GO:0032527
GeneOntologyBiologicalProcessregulation of membrane potential

CACNA1D SCN11A GJD2 GRIA3 GJA5 P2RX7 KCND1 KCND2 KCND3 KCNK15 KCNS1 CNR2

3.84e-0455913812GO:0042391
GeneOntologyBiologicalProcessL-alanine transmembrane transport

SLC38A4 SLC7A8

4.39e-0451382GO:1904557
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

RHCG CACNA1D SCN11A SLC11A2 SLC38A4 TCIRG1 SLC30A7 P2RX7 KCND1 KCND2 KCND3 KCNK15 KCNS1 ATP12A SLC25A28 PLP1

4.53e-0492213816GO:0098662
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

CACNA1D SCN11A SLC11A2 SLC38A4 TCIRG1 GRIA3 SLC30A7 P2RX7 KCND1 KCND2 KCND3 SLC19A1 KCNK15 KCNS1 ATP12A SLC26A11 SLC25A28 PLP1

4.67e-04111513818GO:0034220
GeneOntologyBiologicalProcesscarbohydrate derivative transport

SLC37A1 SLC35A3 P2RX7 SLC19A1 SLC25A31

4.68e-04961385GO:1901264
GeneOntologyBiologicalProcesspotassium ion transport

CACNA1D GJA5 KCND1 KCND2 KCND3 KCNK15 KCNS1 ATP12A

5.00e-042721388GO:0006813
GeneOntologyBiologicalProcessvascular process in circulatory system

ARHGAP42 ABCA2 SLC2A3 SLC7A8 GJA5 SLC19A1 LRP1 SLC16A7 SLC38A3

5.23e-043441389GO:0003018
GeneOntologyBiologicalProcessmembrane repolarization

CACNA1D GJA5 KCND2 KCND3

5.38e-04561384GO:0086009
GeneOntologyBiologicalProcessmonocarboxylic acid transport

SLC16A13 SLC16A9 SLCO1B3 SLCO1B1 P2RX7 ABCB11 SLC16A7

5.87e-042131387GO:0015718
GeneOntologyBiologicalProcessdiol biosynthetic process

ABCA2 ASAH2 SPTLC1

6.05e-04251383GO:0034312
GeneOntologyBiologicalProcessneutral amino acid transport

SLC38A4 MFSD12 SLC7A8 SLC38A3

7.00e-04601384GO:0015804
GeneOntologyBiologicalProcessregulation of protein exit from endoplasmic reticulum

TM9SF4 YOD1 SORL1

7.62e-04271383GO:0070861
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

CACNA1D SCN11A GJA5 KCND3

7.92e-04621384GO:0086002
GeneOntologyBiologicalProcessneuronal action potential

SCN11A GJD2 P2RX7 KCND2

8.42e-04631384GO:0019228
GeneOntologyBiologicalProcessprotein catabolic process in the vacuole

TCIRG1 LRP1 RNF128

8.49e-04281383GO:0007039
GeneOntologyBiologicalProcessmembrane lipid metabolic process

ABCA2 ASAH2 SPTLC1 P2RX7 PLPP2 M6PR CERS4

8.98e-042291387GO:0006643
GeneOntologyBiologicalProcesspositive regulation of protein catabolic process in the vacuole

LRP1 RNF128

9.13e-0471382GO:1904352
GeneOntologyBiologicalProcessphagosome acidification

TCIRG1 RAB39A

9.13e-0471382GO:0090383
GeneOntologyBiologicalProcesscarnitine transmembrane transport

SLC16A9 SLC22A16

9.13e-0471382GO:1902603
GeneOntologyBiologicalProcesspotassium ion transmembrane transport

CACNA1D KCND1 KCND2 KCND3 KCNK15 KCNS1 ATP12A

9.69e-042321387GO:0071805
GeneOntologyCellularComponentbasal part of cell

RHCG SLC11A2 SLCO1B3 SLCO1B1 AQP7 SLC7A8 SLC19A1 LRP1 ABCB11 ATP12A SLC26A11 SLC16A7 SLC38A3

1.63e-0637814013GO:0045178
GeneOntologyCellularComponentbasolateral plasma membrane

RHCG SLCO1B3 SLCO1B1 AQP7 SLC7A8 SLC19A1 LRP1 ABCB11 ATP12A SLC26A11 SLC16A7 SLC38A3

1.71e-0632014012GO:0016323
GeneOntologyCellularComponentbasal plasma membrane

RHCG SLCO1B3 SLCO1B1 AQP7 SLC7A8 SLC19A1 LRP1 ABCB11 ATP12A SLC26A11 SLC16A7 SLC38A3

4.83e-0635414012GO:0009925
GeneOntologyCellularComponentapical part of cell

RHCG CACNA1D FAT4 SLC11A2 SLC2A7 TMEM114 TCIRG1 SLC7A8 SLC19A1 NPC1L1 LRP1 ABCB11 ATP12A SLC26A11 SLC38A3

1.06e-0559214015GO:0045177
GeneOntologyCellularComponentapical plasma membrane

RHCG CACNA1D SLC11A2 SLC2A7 TMEM114 TCIRG1 SLC7A8 SLC19A1 NPC1L1 ABCB11 ATP12A SLC26A11 SLC38A3

2.48e-0548714013GO:0016324
GeneOntologyCellularComponentcaveola

ASAH2 SLC2A14 SLC2A3 PLPP2 KCND2 KCND3

1.03e-041111406GO:0005901
GeneOntologyCellularComponentlysosomal membrane

ABCA2 SLC11A2 TM9SF1 TCIRG1 SLC7A14 MFSD12 SLC2A6 LRP1 SLC26A11 M6PR VPS13B

2.87e-0446214011GO:0005765
GeneOntologyCellularComponentlytic vacuole membrane

ABCA2 SLC11A2 TM9SF1 TCIRG1 SLC7A14 MFSD12 SLC2A6 LRP1 SLC26A11 M6PR VPS13B

2.87e-0446214011GO:0098852
GeneOntologyCellularComponentlysosome

ABCA2 SLC11A2 MAN2B2 TM9SF1 TCIRG1 SLC7A14 MFSD12 BPI SLC2A6 LRP1 RAB39A KIF2A SLC26A11 M6PR VPS13B

3.60e-0481114015GO:0005764
GeneOntologyCellularComponentlytic vacuole

ABCA2 SLC11A2 MAN2B2 TM9SF1 TCIRG1 SLC7A14 MFSD12 BPI SLC2A6 LRP1 RAB39A KIF2A SLC26A11 M6PR VPS13B

3.60e-0481114015GO:0000323
GeneOntologyCellularComponentvacuole

ABCA2 SLC11A2 MAN2B2 TM9SF1 TCIRG1 SLC7A14 MFSD12 MEFV BPI SLC2A6 LRP1 RAB39A KIF2A SLC26A11 M6PR VPS13B

4.13e-0491314016GO:0005773
GeneOntologyCellularComponentplasma membrane raft

ASAH2 SLC2A14 SLC2A3 PLPP2 KCND2 KCND3

4.73e-041471406GO:0044853
GeneOntologyCellularComponentvacuolar membrane

ABCA2 SLC11A2 TM9SF1 TCIRG1 SLC7A14 MFSD12 SLC2A6 LRP1 SLC26A11 M6PR VPS13B

6.25e-0450714011GO:0005774
GeneOntologyCellularComponentmicrotubule associated complex

KIF27 KIF21A KIF4A MEFV KIF2A DNAH11

7.63e-041611406GO:0005875
GeneOntologyCellularComponenttransmembrane transporter complex

CACNA1D SCN11A ABCA2 TCIRG1 GRIA3 KCND1 KCND2 KCND3 KCNK15 KCNS1 ATP12A

8.06e-0452314011GO:1902495
GeneOntologyCellularComponentcytoplasmic vesicle membrane

CIDEB ABCA2 STAB2 SLC11A2 SLC2A14 TCIRG1 GRIA3 AQP7 MFSD12 SLC2A3 RHO PLPP2 NPC1L1 LRP1 ABCB11 RAB39A M6PR VPS13B SORL1

1.16e-03130714019GO:0030659
GeneOntologyCellularComponenttransporter complex

CACNA1D SCN11A ABCA2 TCIRG1 GRIA3 KCND1 KCND2 KCND3 KCNK15 KCNS1 ATP12A

1.21e-0355014011GO:1990351
GeneOntologyCellularComponentvesicle membrane

CIDEB ABCA2 STAB2 SLC11A2 SLC2A14 TCIRG1 GRIA3 AQP7 MFSD12 SLC2A3 RHO PLPP2 NPC1L1 LRP1 ABCB11 RAB39A M6PR VPS13B SORL1

1.36e-03132514019GO:0012506
GeneOntologyCellularComponentsynaptic membrane

CACNA1D SCN11A SLC2A14 GRIA3 TENM2 SLC2A3 KCND1 KCND2 KCND3 LRP1 SLC16A7

1.92e-0358314011GO:0097060
GeneOntologyCellularComponentacrosomal membrane

SLC2A14 SLC2A3 VPS13B

2.09e-03381403GO:0002080
GeneOntologyCellularComponentbrush border membrane

SLC11A2 AQP7 SLC19A1 NPC1L1

2.35e-03831404GO:0031526
GeneOntologyCellularComponentmembrane protein complex

CIDEB CACNA1D SCN11A ABCA2 GJD2 SPCS1 TCIRG1 GRIA3 HM13 STT3B GJA5 KCND1 KCND2 KCND3 KCNK15 LRP1 KCNS1 ATP12A PLP1 SLC25A31

2.36e-03149814020GO:0098796
GeneOntologyCellularComponentplasma membrane protein complex

CACNA1D SCN11A ABCA2 GJD2 GRIA3 GJA5 KCND1 KCND2 KCND3 LRP1 KCNS1 ATP12A PLP1

2.40e-0378514013GO:0098797
GeneOntologyCellularComponentendocytic vesicle membrane

STAB2 TCIRG1 GRIA3 LRP1 RAB39A M6PR

3.09e-032121406GO:0030666
GeneOntologyCellularComponentvoltage-gated potassium channel complex

KCND1 KCND2 KCND3 KCNS1

3.28e-03911404GO:0008076
GeneOntologyCellularComponentGolgi membrane

SLC16A13 ASAH2 MANEA GCNT2 GCNT4 RHO SLC30A7 SLC35A3 ABCB11 RAB39A VPS13B SORL1

3.38e-0372114012GO:0000139
DomainMFS_dom

SLC37A1 SLC16A13 SLC16A9 SLC2A7 SLC22A15 SLC2A14 SLC19A3 SLCO1B3 SLCO1B1 MFSD12 SLC2A3 SLC22A16 SLC19A1 SLC2A6 SLC2A12 SLC16A7

2.49e-1513413616IPR020846
DomainMFS

SLC37A1 SLC16A13 SLC16A9 SLC2A7 SLC22A15 SLC2A14 SLCO1B3 SLCO1B1 MFSD12 SLC2A3 SLC22A16 SLC2A6 SLC2A12 SLC16A7

4.65e-1410813614PS50850
DomainMFS_sugar_transport-like

SLC2A7 SLC22A15 SLC2A14 SLC2A3 SLC22A16 SLC2A6 SLC2A12

6.50e-09361367IPR005828
DomainSugar_tr

SLC2A7 SLC22A15 SLC2A14 SLC2A3 SLC22A16 SLC2A6 SLC2A12

6.50e-09361367PF00083
DomainSugar/inositol_transpt

SLC2A7 SLC2A14 SLC2A3 SLC2A6 SLC2A12

3.61e-08141365IPR003663
DomainSUGAR_TRANSPORT_2

SLC2A7 SLC2A14 SLC2A3 SLC2A6 SLC2A12

1.10e-07171365PS00217
DomainShal-type_N

KCND1 KCND2 KCND3

3.78e-0731363IPR021645
DomainK_chnl_volt-dep_Kv4_C

KCND1 KCND2 KCND3

3.78e-0731363IPR024587
DomainDUF3399

KCND1 KCND2 KCND3

3.78e-0731363PF11879
DomainK_chnl_volt-dep_Kv4

KCND1 KCND2 KCND3

3.78e-0731363IPR003975
DomainShal-type

KCND1 KCND2 KCND3

3.78e-0731363PF11601
DomainSUGAR_TRANSPORT_1

SLC2A7 SLC2A14 SLC2A3 SLC2A6 SLC2A12

7.23e-07241365PS00216
DomainSugar_transporter_CS

SLC2A7 SLC2A14 SLC2A3 SLC2A6 SLC2A12

3.27e-06321365IPR005829
DomainChannel_four-helix_dom

CACNA1D SCN11A KCND1 KCND2 KCND3 KCNS1

3.57e-06571366IPR027359
Domain-

CACNA1D SCN11A KCND1 KCND2 KCND3 KCNS1

3.57e-065713661.20.120.350
DomainKinesin_motor_CS

KIF27 CENPE KIF21A KIF4A KIF2A

1.15e-05411365IPR019821
DomainKinesin-like_fam

KIF27 CENPE KIF21A KIF4A KIF2A

1.47e-05431365IPR027640
Domain-

KIF27 CENPE KIF21A KIF4A KIF2A

1.64e-054413653.40.850.10
DomainKinesin

KIF27 CENPE KIF21A KIF4A KIF2A

1.64e-05441365PF00225
DomainKISc

KIF27 CENPE KIF21A KIF4A KIF2A

1.64e-05441365SM00129
DomainKINESIN_MOTOR_1

KIF27 CENPE KIF21A KIF4A KIF2A

1.64e-05441365PS00411
DomainKinesin_motor_dom

KIF27 CENPE KIF21A KIF4A KIF2A

1.64e-05441365IPR001752
DomainKINESIN_MOTOR_2

KIF27 CENPE KIF21A KIF4A KIF2A

1.64e-05441365PS50067
DomainK_chnl_volt-dep_Kv

KCND1 KCND2 KCND3 KCNS1

4.14e-05271364IPR003968
DomainGlc_transpt_3

SLC2A14 SLC2A3

5.26e-0521362IPR002945
DomainEGF

FAT4 FRAS1 STAB2 FAT3 LAMA1 TENM2 THBS2 LRP1 SORL1

5.68e-052351369SM00181
DomainEGF-like_dom

FAT4 FRAS1 STAB2 FAT3 LAMA1 TENM2 THBS2 LRP1 SORL1

8.86e-052491369IPR000742
DomainVG_K_chnl

KCND1 KCND2 KCND3 KCNS1

9.34e-05331364IPR028325
DomainMYELIN_PLP_1

GPM6B PLP1

1.57e-0431362PS00575
DomainMyelin_PLP

GPM6B PLP1

1.57e-0431362IPR001614
DomainMyelin_PLP_CS

GPM6B PLP1

1.57e-0431362IPR018237
DomainMyelin_PLP

GPM6B PLP1

1.57e-0431362PF01275
DomainMYELIN_PLP_2

GPM6B PLP1

1.57e-0431362PS01004
DomainPLP

GPM6B PLP1

1.57e-0431362SM00002
DomainIon_trans_dom

CACNA1D SCN11A KCND1 KCND2 KCND3 KCNS1

1.87e-041141366IPR005821
DomainIon_trans

CACNA1D SCN11A KCND1 KCND2 KCND3 KCNS1

1.87e-041141366PF00520
DomainMFS_1

SLC37A1 SLC16A13 SLC16A9 MFSD12 SLC16A7

2.47e-04771365PF07690
DomainMFS

SLC37A1 SLC16A13 SLC16A9 MFSD12 SLC16A7

2.47e-04771365IPR011701
DomainEGF_CA

FAT4 STAB2 FAT3 TENM2 THBS2 LRP1

2.70e-041221366SM00179
DomainEGF-like_Ca-bd_dom

FAT4 STAB2 FAT3 TENM2 THBS2 LRP1

2.95e-041241366IPR001881
DomainFolate_carrier

SLC19A3 SLC19A1

3.13e-0441362PF01770
DomainFolate_carrier

SLC19A3 SLC19A1

3.13e-0441362IPR002666
DomainEMP70

TM9SF4 TM9SF1

3.13e-0441362PF02990
DomainEMP70

TM9SF4 TM9SF1

3.13e-0441362IPR004240
DomainBPI/LBP

BPI BPIFB2

5.19e-0451362IPR030675
DomainBTB_2

KCND1 KCND2 KCND3 KCNS1

5.97e-04531364PF02214
DomainT1-type_BTB

KCND1 KCND2 KCND3 KCNS1

5.97e-04531364IPR003131
DomainEGF-like_CS

FAT4 STAB2 FAT3 LAMA1 TENM2 THBS2 LRP1 SORL1

6.60e-042611368IPR013032
DomainEGF_2

FAT4 STAB2 FAT3 LAMA1 TENM2 THBS2 LRP1 SORL1

7.29e-042651368PS01186
DomainLaminin_G

FAT4 FAT3 LAMA1 THBS2

8.42e-04581364IPR001791
DomainGlyco_trans_14

GCNT2 GCNT4

1.43e-0381362IPR003406
DomainBranch

GCNT2 GCNT4

1.43e-0381362PF02485
DomainEGF_3

FAT4 STAB2 FAT3 TENM2 THBS2 LRP1 SORL1

1.69e-032351367PS50026
DomainBPI2

BPI BPIFB2

1.83e-0391362SM00329
DomainLBP_BPI_CETP

BPI BPIFB2

1.83e-0391362PS00400
DomainLBP_BPI_CETP_C

BPI BPIFB2

2.28e-03101362PF02886
DomainLAM_G_DOMAIN

FAT4 FAT3 LAMA1

2.64e-03381363PS50025
DomainEGF_1

FAT4 STAB2 FAT3 LAMA1 TENM2 THBS2 LRP1

2.67e-032551367PS00022
DomainHlyIII

PAQR5 PAQR7

2.77e-03111362PF03006
DomainAdipoR/HlyIII-related

PAQR5 PAQR7

2.77e-03111362IPR004254
Domain-

TENM2 LRP1 SORL1

2.85e-033913632.120.10.30
DomainLaminin_G_2

FAT4 FAT3 LAMA1

3.06e-03401363PF02210
DomainEGF_dom

STAB2 THBS2

3.31e-03121362IPR024731
DomainOA_transporter

SLCO1B3 SLCO1B1

3.31e-03121362IPR004156
DomainEGF_3

STAB2 THBS2

3.31e-03121362PF12947
DomainLipid-bd_serum_glycop_C

BPI BPIFB2

3.31e-03121362IPR001124
DomainOATP

SLCO1B3 SLCO1B1

3.31e-03121362PF03137
DomainEGF_CA

FAT4 FAT3 THBS2 LRP1

3.60e-03861364PF07645
DomainAA_permease_2

SLC7A14 SLC7A8

3.90e-03131362PF13520
DomainLBP_BPI_CETP

BPI BPIFB2

3.90e-03131362PF01273
DomainBPI/LBP/Plunc

BPI BPIFB2

3.90e-03131362IPR032942
DomainAA/rel_permease1

SLC7A14 SLC7A8

3.90e-03131362IPR002293
DomainBactericidal_perm-incr_a/b_dom

BPI BPIFB2

3.90e-03131362IPR017943
DomainLipid-bd_serum_glycop_N

BPI BPIFB2

3.90e-03131362IPR017942
DomainLamG

FAT4 FAT3 LAMA1

4.02e-03441363SM00282
DomainLdl_recept_b

LRP1 SORL1

4.52e-03141362PF00058
DomainLDLRB

LRP1 SORL1

4.52e-03141362PS51120
Domain6-blade_b-propeller_TolB-like

TENM2 LRP1 SORL1

4.56e-03461363IPR011042
Domain-

FAT4 FAT3 LAMA1 THBS2

5.14e-039513642.60.120.200
DomainLY

LRP1 SORL1

5.19e-03151362SM00135
DomainLDLR_classB_rpt

LRP1 SORL1

5.19e-03151362IPR000033
DomainConA-like_dom

FAT4 FAT3 LAMA1 MEFV BTN3A3 THBS2

5.40e-032191366IPR013320
DomainGrowth_fac_rcpt_

FAT4 FRAS1 STAB2 LAMA1 LRP1

5.71e-031561365IPR009030
DomainAa_trans

SLC38A4 SLC38A3

6.66e-03171362PF01490
DomainAA_transpt_TM

SLC38A4 SLC38A3

6.66e-03171362IPR013057
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

RHCG SLC11A2 SLC38A4 SLC2A7 SLC22A15 SLC2A14 SLCO1B3 SLCO1B1 SLC2A3 SLC7A8 SLC35A3 SLC22A16 SLC2A6 SLC26A11 SLC2A12 SLC16A7 SLC38A3

6.23e-1223811317MM15076
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

RHCG SLC11A2 SLC38A4 SLC2A7 SLC22A15 SLC2A14 SLCO1B3 SLCO1B1 SLC2A3 SLC7A8 SLC35A3 SLC22A16 SLC2A6 SLC26A11 SLC2A12 SLC16A7 SLC38A3

1.28e-1124911317M5988
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

RHCG ABCA2 SLC11A2 SLC38A4 SLC2A7 SLC22A15 SLC2A14 TCIRG1 SLCO1B3 SLCO1B1 AQP7 SLC2A3 SLC7A8 SLC35A3 SLC22A16 SLC2A6 ATP12A SLC26A11 SLC2A12 SLC16A7 SLC38A3

9.02e-0868111321MM14985
PathwayREACTOME_CELLULAR_HEXOSE_TRANSPORT

SLC2A7 SLC2A14 SLC2A3 SLC2A6 SLC2A12

3.22e-07191135MM14718
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

RHCG ABCA2 SLC11A2 SLC38A4 SLC2A7 SLC22A15 SLC2A14 TCIRG1 SLCO1B3 SLCO1B1 AQP7 SLC2A3 SLC7A8 SLC35A3 SLC22A16 SLC2A6 ATP12A SLC26A11 SLC2A12 SLC16A7 SLC38A3

3.30e-0773611321M27287
PathwayREACTOME_CELLULAR_HEXOSE_TRANSPORT

SLC2A7 SLC2A14 SLC2A3 SLC2A6 SLC2A12

5.56e-07211135M27058
PathwayREACTOME_PHASE_1_INACTIVATION_OF_FAST_NA_CHANNELS

KCND1 KCND2 KCND3

1.71e-0571133M27457
PathwayREACTOME_PHASE_1_INACTIVATION_OF_FAST_NA_CHANNELS

KCND1 KCND2 KCND3

1.71e-0571133MM15199
PathwayREACTOME_KINESINS

KIF27 CENPE KIF21A KIF4A KIF2A

9.10e-05571135MM15714
PathwayWP_ENTEROHEPATIC_CIRCULATION_OF_BILE_ACIDS

SLCO1B3 SLCO1B1 ABCB11

1.05e-04121133M48096
PathwayREACTOME_KINESINS

KIF27 CENPE KIF21A KIF4A KIF2A

1.26e-04611135M977
PathwayREACTOME_INTRA_GOLGI_AND_RETROGRADE_GOLGI_TO_ER_TRAFFIC

KIF27 CENPE KIF21A KIF4A RAB3GAP2 RAB39A KIF2A M6PR

1.39e-041891138MM15356
PathwayREACTOME_INTRA_GOLGI_AND_RETROGRADE_GOLGI_TO_ER_TRAFFIC

KIF27 CENPE KIF21A KIF4A RAB3GAP2 RAB39A KIF2A M6PR

2.26e-042031138M27654
PathwayWP_DRAVET_SYNDROME_SCN1AA1783V_POINT_MUTATION_MODEL

SLC2A14 GRIA3 SLC2A3 SLC16A7 SLC38A3

2.95e-04731135MM16641
PathwayREACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS

KCND1 KCND2 KCND3 KCNS1

3.15e-04411134MM14546
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

RHCG SLC11A2 SLC22A15 SLC22A16 SLC16A7

3.56e-04761135MM15072
PathwayREACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS

SLCO1B3 SLCO1B1 ABCB11

3.75e-04181133M4862
PathwayREACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS

KCND1 KCND2 KCND3 KCNS1

3.80e-04431134M1056
PathwayREACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS

SLCO1B3 SLCO1B1 ABCB11

4.43e-04191133MM14612
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

RHCG SLC11A2 SLC22A15 SLC22A16 SLC16A7

5.65e-04841135M27334
PathwayREACTOME_GOLGI_TO_ER_RETROGRADE_TRANSPORT

KIF27 CENPE KIF21A KIF4A RAB3GAP2 KIF2A

6.44e-041311136MM15497
PathwayREACTOME_GOLGI_TO_ER_RETROGRADE_TRANSPORT

KIF27 CENPE KIF21A KIF4A RAB3GAP2 KIF2A

7.25e-041341136M27751
PathwayREACTOME_SPHINGOLIPID_METABOLISM

ASAH2 SPTLC1 PLPP2 M6PR CERS4

8.55e-04921135MM15086
PathwayREACTOME_COPI_DEPENDENT_GOLGI_TO_ER_RETROGRADE_TRAFFIC

KIF27 CENPE KIF21A KIF4A KIF2A

1.14e-03981135MM15352
PathwayWP_SPHINGOLIPID_METABOLISM_INTEGRATED_PATHWAY

SPTLC1 PLPP2 CERS4

1.14e-03261133M39784
PathwayREACTOME_SLC_TRANSPORTER_DISORDERS

SLC11A2 SLCO1B3 NUP214 SLCO1B1 SLC35A3

1.19e-03991135M27474
PathwayREACTOME_COPI_DEPENDENT_GOLGI_TO_ER_RETROGRADE_TRAFFIC

KIF27 CENPE KIF21A KIF4A KIF2A

1.24e-031001135M27650
PathwayWP_SPHINGOLIPID_METABOLISM_OVERVIEW

SPTLC1 PLPP2 CERS4

1.27e-03271133M39863
PathwayWP_DISORDERS_OF_BILE_ACID_SYNTHESIS_AND_BILIARY_TRANSPORT

SLCO1B3 SLCO1B1 ABCB11

1.57e-03291133M45551
PathwayREACTOME_SPHINGOLIPID_METABOLISM

ASAH2 SPTLC1 PLPP2 M6PR CERS4

1.68e-031071135M14857
PathwayREACTOME_ORGANIC_CATION_TRANSPORT

SLC22A15 SLC22A16

1.73e-0381132MM15191
PathwayWP_SPHINGOLIPID_PATHWAY

ASAH2 SPTLC1 CERS4

1.74e-03301133M39501
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

RCE1 FAT4 FRAS1 ABCA2 MAN2B2 MAT2B SPCS1 TM9SF4 TM9SF1 LAMA1 SPTLC1 KIF4A MANEA HM13 STT3B SLC30A7 CNNM3 CLPTM1 LRP1 KIF2A USP15 ALG6 M6PR SORL1

9.21e-1112011402435696571
Pubmed

Unique clustering of A-type potassium channels on different cell types of the main olfactory bulb.

KCND1 KCND2 KCND3

6.38e-083140318371079
Pubmed

Gene structures and expression profiles of three human KCND (Kv4) potassium channels mediating A-type currents I(TO) and I(SA).

KCND1 KCND2 KCND3

6.38e-083140310729221
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

CACNA1D SCN11A GJA5 P2RX7 KCND1 KCND2 KCND3 KCNS1

1.02e-07139140816985003
Pubmed

Organization of the mouse microfibril-associated glycoprotein-2 (MAGP-2) gene.

SLC2A14 SLC2A3 M6PR

6.35e-075140310723723
Pubmed

Adaptation of nutrient supply to fetal demand in the mouse involves interaction between the Igf2 gene and placental transporter systems.

SLC38A4 SLC2A14 SLC2A3

6.35e-075140316365304
Pubmed

Complex patterns of cell growth in the placenta in normal pregnancy and as adaptations to maternal diet restriction.

SLC38A4 SLC2A14 SLC2A3 UGP2

7.37e-0718140431917811
Pubmed

Analysis of DNA methylation and histone modification profiles of liver-specific transporters.

SLCO1B3 SLCO1B1 ABCB11

1.27e-066140319047482
Pubmed

Nutrient Transporter Gene Expression in the Early Conceptus-Implications From Two Mouse Models of Diabetic Pregnancy.

SLC2A14 SLC2A3 SLC2A6 SLC2A12

2.98e-0625140435478964
Pubmed

Blood-Brain Barrier: From Physiology to Disease and Back.

ABCA2 CLDN12 SLC7A8 SLC19A1 LRP1 SLC38A3

4.43e-06105140630280653
Pubmed

Altered placental function of 11beta-hydroxysteroid dehydrogenase 2 knockout mice.

SLC38A4 SLC2A14 SLC2A3

5.27e-069140318845627
Pubmed

Neural Deletion of Glucose Transporter Isoform 3 Creates Distinct Postnatal and Adult Neurobehavioral Phenotypes.

SLC2A14 SLC2A3 SLC16A7

1.03e-0511140330232223
Pubmed

Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference.

CENPE KIF4A KIF2A

1.03e-0511140315843429
Pubmed

All kinesin superfamily protein, KIF, genes in mouse and human.

CENPE KIF21A KIF4A KIF2A

1.50e-0537140411416179
Pubmed

Reprogramming- and pluripotency-associated membrane proteins in mouse stem cells revealed by label-free quantitative proteomics.

SLC2A14 SLC2A3

1.61e-052140223615220
Pubmed

The extended GLUT-family of sugar/polyol transport facilitators: nomenclature, sequence characteristics, and potential function of its novel members (review).

SLC2A7 SLC2A12

1.61e-052140211780753
Pubmed

Modulation of transporter activity of OATP1B1 and OATP1B3 by the major active components of Radix Ophiopogonis.

SLCO1B3 SLCO1B1

1.61e-052140229944058
Pubmed

Copy-Number Variation of the Glucose Transporter Gene SLC2A3 and Congenital Heart Defects in the 22q11.2 Deletion Syndrome.

SLC2A14 SLC2A3

1.61e-052140225892112
Pubmed

SLCO1B1 and SLCO1B3 genetic mutations in Taiwanese patients with Rotor syndrome.

SLCO1B3 SLCO1B1

1.61e-052140236964102
Pubmed

CD205+ polymorphonuclear myeloid-derived suppressor cells suppress antitumor immunity by overexpressing GLUT3.

SLC2A14 SLC2A3

1.61e-052140233368883
Pubmed

Contribution of OATP1B1 and OATP1B3 to the disposition of sorafenib and sorafenib-glucuronide.

SLCO1B3 SLCO1B1

1.61e-052140223340295
Pubmed

Neuronal functions, feeding behavior, and energy balance in Slc2a3+/- mice.

SLC2A14 SLC2A3

1.61e-052140218780771
Pubmed

Further Studies to Support the Use of Coproporphyrin I and III as Novel Clinical Biomarkers for Evaluating the Potential for Organic Anion Transporting Polypeptide 1B1 and OATP1B3 Inhibition.

SLCO1B3 SLCO1B1

1.61e-052140229777022
Pubmed

Down-regulation of OATP1B proteins correlates with hyperbilirubinemia in advanced cholestasis.

SLCO1B3 SLCO1B1

1.61e-052140226191226
Pubmed

Utility of Oatp1a/1b-knockout and OATP1B1/3-humanized mice in the study of OATP-mediated pharmacokinetics and tissue distribution: case studies with pravastatin, atorvastatin, simvastatin, and carboxydichlorofluorescein.

SLCO1B3 SLCO1B1

1.61e-052140224194513
Pubmed

Expression of mouse-GLUT3 and human-GLUT3 glucose transporter proteins in brain.

SLC2A14 SLC2A3

1.61e-05214021734877
Pubmed

Sevoflurane Induces Learning and Memory Impairment in Young Mice Through a Reduction in Neuronal Glucose Transporter 3.

SLC2A14 SLC2A3

1.61e-052140231884568
Pubmed

Evaluation of organic anion transporting polypeptide 1B1 and 1B3 humanized mice as a translational model to study the pharmacokinetics of statins.

SLCO1B3 SLCO1B1

1.61e-052140224855184
Pubmed

A study on altered expression of serine palmitoyltransferase and ceramidase in psoriatic skin lesion.

ASAH2 SPTLC1

1.61e-052140217982236
Pubmed

Preclinical Mouse Models To Study Human OATP1B1- and OATP1B3-Mediated Drug-Drug Interactions in Vivo.

SLCO1B3 SLCO1B1

1.61e-052140226474710
Pubmed

Effects of anthocyans on the expression of organic anion transporting polypeptides (SLCOs/OATPs) in primary human hepatocytes.

SLCO1B3 SLCO1B1

1.61e-052140225578040
Pubmed

Temporal and spatial distribution of murine placental and brain GLUT3-luciferase transgene as a readout of in vivo transcription.

SLC2A14 SLC2A3

1.61e-052140223193055
Pubmed

PLP1 and GPM6B intragenic copy number analysis by MAPH in 262 patients with hypomyelinating leukodystrophies: Identification of one partial triplication and two partial deletions of PLP1.

GPM6B PLP1

1.61e-052140216416265
Pubmed

Mutations in the genes KCND2 and KCND3 encoding the ion channels Kv4.2 and Kv4.3, conducting the cardiac fast transient outward current (ITO,f), are not a frequent cause of long QT syndrome.

KCND2 KCND3

1.61e-052140215563876
Pubmed

Prediction of organic anion-transporting polypeptide 1B1- and 1B3-mediated hepatic uptake of statins based on transporter protein expression and activity data.

SLCO1B3 SLCO1B1

1.61e-052140224989890
Pubmed

Gene expression of GLUT3 glucose transporter regulated by glucose in vivo in mouse brain and in vitro in neuronal cell cultures from rat embryos.

SLC2A14 SLC2A3

1.61e-05214028198523
Pubmed

S-glutathionylation of an auxiliary subunit confers redox sensitivity to Kv4 channel inactivation.

KCND1 KCND2

1.61e-052140224675763
Pubmed

Kv4.3-Encoded Fast Transient Outward Current Is Presented in Kv4.2 Knockout Mouse Cardiomyocytes.

KCND2 KCND3

1.61e-052140226196737
Pubmed

Genomic organisation and chromosomal localisation of two members of the KCND ion channel family, KCND2 and KCND3.

KCND2 KCND3

1.61e-052140210942109
Pubmed

Expression of organic anion-transporting polypeptides 1B1 and 1B3 in ovarian cancer cells: relevance for paclitaxel transport.

SLCO1B3 SLCO1B1

1.61e-052140221719246
Pubmed

Organic anion transporting polypeptide 1B1 (OATP1B1) and OATP1B3: genetic variability and haplotype analysis in white Canadians.

SLCO1B3 SLCO1B1

1.61e-052140220877131
Pubmed

Transport of fluorescent chenodeoxycholic acid via the human organic anion transporters OATP1B1 and OATP1B3.

SLCO1B3 SLCO1B1

1.61e-052140216534140
Pubmed

Altered lactate metabolism in Huntington's disease is dependent on GLUT3 expression.

SLC2A14 SLC2A3

1.61e-052140229582588
Pubmed

Participation of the lipoprotein receptor LRP1 in hypoxia-HSP90alpha autocrine signaling to promote keratinocyte migration.

LRP1 HSP90AA2P

1.61e-052140219383717
Pubmed

Effect of pregnane X receptor ligands on transport mediated by human OATP1B1 and OATP1B3.

SLCO1B3 SLCO1B1

1.61e-052140218321482
Pubmed

Placental glucose and amino acid transport in calorie-restricted wild-type and Glut3 null heterozygous mice.

SLC2A14 SLC2A3

1.61e-052140222700768
Pubmed

Glucose transporter isoform-3-null heterozygous mutation causes sexually dimorphic adiposity with insulin resistance.

SLC2A14 SLC2A3

1.61e-052140218445753
Pubmed

Interaction of oral antidiabetic drugs with hepatic uptake transporters: focus on organic anion transporting polypeptides and organic cation transporter 1.

SLCO1B3 SLCO1B1

1.61e-052140218314419
Pubmed

Sex-Specific Life Course Changes in the Neuro-Metabolic Phenotype of Glut3 Null Heterozygous Mice: Ketogenic Diet Ameliorates Electroencephalographic Seizures and Improves Sociability.

SLC2A14 SLC2A3

1.61e-052140228324109
Pubmed

OATP 1B1/1B3 expression in hepatocellular carcinomas treated with orthotopic liver transplantation.

SLCO1B3 SLCO1B1

1.61e-052140221691816
Pubmed

Dendritic Kv4.2 potassium channels selectively mediate spatial pattern separation in the dentate gyrus.

KCND2 KCND3

1.61e-052140234386734
Pubmed

Expression of the brain-type glucose transporter is restricted to brain and neuronal cells in mice.

SLC2A14 SLC2A3

1.61e-05214021516757
Pubmed

Glucose Transporter 3 Potentiates Degranulation and Is Required for Platelet Activation.

SLC2A14 SLC2A3

1.61e-052140228663252
Pubmed

Linking organic anion transporting polypeptide 1B1 and 1B3 (OATP1B1 and OATP1B3) interaction profiles to hepatotoxicity - The hyperbilirubinemia use case.

SLCO1B3 SLCO1B1

1.61e-052140228063966
Pubmed

Membrane progestin receptors alpha and gamma in renal epithelium.

PAQR5 PAQR7

1.61e-052140218722485
Pubmed

Neuronal glucose transporter isoform 3 deficient mice demonstrate features of autism spectrum disorders.

SLC2A14 SLC2A3

1.61e-052140219506559
Pubmed

Long-lasting inhibitory effects of cyclosporin A, but not tacrolimus, on OATP1B1- and OATP1B3-mediated uptake.

SLCO1B3 SLCO1B1

1.61e-052140222240838
Pubmed

Human organic anion transporter 1B1 and 1B3 function as bidirectional carriers and do not mediate GSH-bile acid cotransport.

SLCO1B3 SLCO1B1

1.61e-052140217412826
Pubmed

Isolation and characterization of the human gene encoding Ito: further diversity by alternative mRNA splicing.

KCND2 KCND3

1.61e-05214029843794
Pubmed

Canine brain glucose transporter 3: gene sequence, phylogenetic comparisons and analysis of functional sites.

SLC2A14 SLC2A3

1.61e-05214028654954
Pubmed

A critical role for the cholesterol-associated proteolipids PLP and M6B in myelination of the central nervous system.

GPM6B PLP1

1.61e-052140223322581
Pubmed

Visualization of hepatic uptake transporter function in healthy subjects by using gadoxetic acid-enhanced MR imaging.

SLCO1B3 SLCO1B1

1.61e-052140222771883
Pubmed

Establishment of a set of double transfectants coexpressing organic anion transporting polypeptide 1B3 and hepatic efflux transporters for the characterization of the hepatobiliary transport of telmisartan acylglucuronide.

SLCO1B3 SLCO1B1

1.61e-052140218180273
Pubmed

Structure of human drug transporters OATP1B1 and OATP1B3.

SLCO1B3 SLCO1B1

1.61e-052140237723174
Pubmed

Adult glut3 homozygous null mice survive to demonstrate neural excitability and altered neurobehavioral responses reminiscent of neurodevelopmental disorders.

SLC2A14 SLC2A3

1.61e-052140233482226
Pubmed

Effects of Rifampin, a potent inducer of drug-metabolizing enzymes and an inhibitor of OATP1B1/3 transport, on the single dose pharmacokinetics of anacetrapib.

SLCO1B3 SLCO1B1

1.61e-052140223670789
Pubmed

Differential expression of I(A) channel subunits Kv4.2 and Kv4.3 in mouse visual cortical neurons and synapses.

KCND2 KCND3

1.61e-052140217122053
Pubmed

Bosentan is a substrate of human OATP1B1 and OATP1B3: inhibition of hepatic uptake as the common mechanism of its interactions with cyclosporin A, rifampicin, and sildenafil.

SLCO1B3 SLCO1B1

1.61e-052140217496208
Pubmed

Rotor Syndrome

SLCO1B3 SLCO1B1

1.61e-052140223236639
Pubmed

Expression Patterns of Organic Anion Transporting Polypeptides 1B1 and 1B3 Protein in Human Pediatric Liver.

SLCO1B3 SLCO1B1

1.61e-052140227098745
Pubmed

Introduction of aromatic ring-containing substituents in cyclic nucleotides is associated with inhibition of toxin uptake by the hepatocyte transporters OATP 1B1 and 1B3.

SLCO1B3 SLCO1B1

1.61e-052140224740327
Pubmed

Glucose Transporter 3 is Essential for the Survival of Breast Cancer Cells in the Brain.

SLC2A14 SLC2A3

1.61e-052140231817208
Pubmed

Brain glucose transporter (Glut3) haploinsufficiency does not impair mouse brain glucose uptake.

SLC2A14 SLC2A3

1.61e-052140221316350
Pubmed

UGT-dependent regioselective glucuronidation of ursodeoxycholic acid and obeticholic acid and selective transport of the consequent acyl glucuronides by OATP1B1 and 1B3.

SLCO1B3 SLCO1B1

1.61e-052140231299240
Pubmed

In vitro OATP1B1 and OATP1B3 inhibition is associated with observations of benign clinical unconjugated hyperbilirubinemia.

SLCO1B3 SLCO1B1

1.61e-052140223886114
Pubmed

OATP1B1/1B3 activity in plated primary human hepatocytes over time in culture.

SLCO1B3 SLCO1B1

1.61e-052140221787759
Pubmed

The Diet1 locus confers protection against hypercholesterolemia through enhanced bile acid metabolism.

SLCO1B3 SLCO1B1 ABCB11

1.77e-0513140311682476
Pubmed

International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels.

KCND1 KCND2 KCND3 KCNS1

2.05e-0540140416382104
Pubmed

FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.

SPCS1 SPTLC1 HM13 STT3B SLC30A7 CNNM3 BTN3A3 RAB3GAP2 CLPTM1 CERS4

2.14e-054681401031056421
Pubmed

Functional suppression of Kcnq1 leads to early sodium channel remodelling and cardiac conduction system dysmorphogenesis.

GJA5 KCND2 KCND3

2.25e-0514140323542581
Pubmed

The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond.

SLC16A13 SLC16A9 SLC16A7

2.25e-0514140312739169
Pubmed

The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.

SLCO1B3 SLCO1B1 SLC35A3 SLC19A1 SLC26A11 SLC2A12 SORL1

2.56e-05212140719521566
Pubmed

Neuronal interleukin-16 (NIL-16): a dual function PDZ domain protein.

KCND1 KCND2 KCND3

2.80e-0515140310479680
Pubmed

Placental and fetal characteristics of the Ohia mouse line recapitulate outcomes in human hypoplastic left heart syndrome.

SLC2A14 SLC2A3 SLC7A8

3.44e-0516140334890862
Pubmed

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.

GPM6B SLC2A14 SLC2A3 SLC7A8 CNNM3 KCND2 KCND3 SLC16A7 SLC38A3

4.12e-05405140938187761
Pubmed

Preincubation With Everolimus and Sirolimus Reduces Organic Anion-Transporting Polypeptide (OATP)1B1- and 1B3-Mediated Transport Independently of mTOR Kinase Inhibition: Implication in Assessing OATP1B1- and OATP1B3-Mediated Drug-Drug Interactions.

SLCO1B3 SLCO1B1

4.81e-053140231047942
Pubmed

NFκB up-regulation of glucose transporter 3 is essential for hyperactive mammalian target of rapamycin-induced aerobic glycolysis and tumor growth.

SLC2A14 SLC2A3

4.81e-053140225578782
Pubmed

Multiple Genetic Modifiers of Bilirubin Metabolism Involvement in Significant Neonatal Hyperbilirubinemia in Patients of Chinese Descent.

SLCO1B3 SLCO1B1

4.81e-053140226146841
Pubmed

SLCO1B1, SLCO2B1, and SLCO1B3 polymorphisms and susceptibility to bladder cancer risk.

SLCO1B3 SLCO1B1

4.81e-053140224762081
Pubmed

Glucose transporter GLUT3: ontogeny, targeting, and role in the mouse blastocyst.

SLC2A14 SLC2A3

4.81e-05314029108057
Pubmed

Linking supply to demand: the neuronal monocarboxylate transporter MCT2 and the alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionic acid receptor GluR2/3 subunit are associated in a common trafficking process.

GRIA3 SLC16A7

4.81e-053140219453627
Pubmed

Characterization of organic anion transporting polypeptide 1b2-null mice: essential role in hepatic uptake/toxicity of phalloidin and microcystin-LR.

SLCO1B3 SLCO1B1

4.81e-053140218296417
Pubmed

Effects of tuberculosis, race, and human gene SLCO1B1 polymorphisms on rifampin concentrations.

SLCO1B3 SLCO1B1

4.81e-053140220660695
Pubmed

Rod and cone contributions to horizontal cell light responses in the mouse retina.

GJD2 RHO

4.81e-053140218596157
Pubmed

Molecular dissection of I(A) in cortical pyramidal neurons reveals three distinct components encoded by Kv4.2, Kv4.3, and Kv1.4 alpha-subunits.

KCND2 KCND3

4.81e-053140220371829
Pubmed

Toll-like receptor 3 controls QT interval on the electrocardiogram by targeting the degradation of Kv4.2/4.3 channels in the endoplasmic reticulum.

KCND2 KCND3

4.81e-053140230758987
Pubmed

Influence of genomic ancestry on the distribution of SLCO1B1, SLCO1B3 and ABCB1 gene polymorphisms among Brazilians.

SLCO1B3 SLCO1B1

4.81e-053140222136368
Pubmed

Significant reduction of the GLUT3 level, but not GLUT1 level, was observed in the brain tissues of several scrapie experimental animals and scrapie-infected cell lines.

SLC2A14 SLC2A3

4.81e-053140224243341
Pubmed

Impact of regulatory polymorphisms in organic anion transporter genes in the human liver.

SLCO1B3 SLCO1B1

4.81e-053140219620935
Pubmed

Role of heteromultimers in the generation of myocardial transient outward K+ currents.

KCND2 KCND3

4.81e-053140211909823
InteractionFXYD6-FXYD2 interactions

TMPPE SLC16A13 SPCS1 SLC19A3 SLC7A8 CERS4

1.22e-07351376int:FXYD6-FXYD2
InteractionSLC22A9 interactions

TMPPE ABCA2 TM9SF4 MANEA MFSD12 STT3B CNNM3 ALG6

1.65e-061201378int:SLC22A9
GeneFamilySolute carriers

RHCG SLC37A1 SLC16A13 SLC11A2 SLC16A9 SLC38A4 SLC2A7 SLC22A15 SLC2A14 SLC19A3 SLCO1B3 SLCO1B1 SLC7A14 SLC2A3 SLC30A7 SLC7A8 SLC35A3 SLC22A16 SLC19A1 SLC2A6 SLC26A11 SLC25A28 SLC2A12 SLC16A7 SLC38A3 SLC25A31

2.37e-2039510626752
GeneFamilyKinesins|Pleckstrin homology domain containing

KIF27 CENPE KIF21A KIF4A KIF2A

7.13e-06461065622
GeneFamilyPotassium voltage-gated channels

KCND1 KCND2 KCND3 KCNS1

8.67e-05401064274
GeneFamilyTransmembrane 9 superfamily members

TM9SF4 TM9SF1

2.03e-04410621239
GeneFamilyGlucosaminyl (N-acetyl) transferases/xylosyltransferases

GCNT2 GCNT4

9.32e-0481062441
GeneFamilyProgestin and adipoQ receptor family

PAQR5 PAQR7

1.81e-03111062930
GeneFamilyBPI fold containing

BPI BPIFB2

3.87e-03161062456
GeneFamilyCadherin related

FAT4 FAT3

4.37e-0317106224
ToppCellmetastatic_Brain-Endothelial_cells-Lymphatic_ECs|Endothelial_cells / Location, Cell class and cell subclass

STAB2 SLC38A4 PAQR5 SLC7A8 BPI LRP1 QSER1 SLC2A12

8.05e-08176138842541dfe20eb29625d47c0bb79bf3c21a2460340
ToppCellmetastatic_Brain-Endothelial_cells-Lymphatic_ECs|metastatic_Brain / Location, Cell class and cell subclass

STAB2 SLC38A4 TM9SF1 PAQR5 CNNM3 BPI SLC2A12

1.47e-06179138756fe381ffbaba3a4f2f587a3e367b0d11fbd4a2a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1D SLC22A15 LAMA1 SLC19A3 GCNT2 TMEM101 SLC16A7

2.03e-061881387bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1D SLC22A15 LAMA1 SLC19A3 GCNT2 TMEM101 SLC16A7

2.03e-061881387eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1D SLC22A15 LAMA1 SLC19A3 PAQR5 GCNT2 SLC16A7

2.10e-061891387977a813e5d7a5a561c1fced2bbf21c20056b88d8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1D SLC22A15 LAMA1 SLC19A3 PAQR5 GCNT2 SLC16A7

2.18e-061901387e252e925600e6457fa6e362a55217f4cffa75cdb
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

ARHGAP42 FAT4 GRIA3 ODC1 PLXNA4 LRP1 PLP1

3.06e-062001387a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCellfacs-Heart-LV-18m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GCNT2 MEFV SLC2A3 SLC2A6 SORL1 DNAH11

7.72e-0615113865893a51585a65f1902cf85124a5ed9f02b4eb82a
ToppCellfacs-Heart-LV-18m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GCNT2 MEFV SLC2A3 SLC2A6 SORL1 DNAH11

7.72e-061511386771224e0d6fccfa4225b3adccd7bc22a89a40793
ToppCellfacs-Heart-Unknown-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 COL28A1 KCND2 RNF128 PLP1 SLC38A3

9.64e-0615713868d30d8e6fae93afcada6bd68799439335cd65b69
ToppCellfacs-Heart-Unknown-3m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 COL28A1 KCND2 RNF128 PLP1 SLC38A3

9.64e-0615713862ac4695d9e4ca8d4ba19c555e9a1d86ac8f398ab
ToppCellfacs-Heart-Unknown-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 COL28A1 KCND2 RNF128 PLP1 SLC38A3

9.64e-0615713868a393eece90fb9a1b7c356736bdb36277261fbd3
ToppCellfacs-Trachea-18m-Hematologic-myeloid-granulocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCN11A CCRL2 MEFV RHO SLC7A8 RNF128

1.11e-051611386d1f2e5245c7c247b684f48f9f877e149a3ee7c06
ToppCellfacs-Trachea-nan-18m-Myeloid-granulocyte|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN11A CCRL2 MEFV RHO SLC7A8 RNF128

1.32e-0516613867f8b4cf63c3e292ae421f111edaa4572717f4db1
ToppCellfacs-Heart-RV-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6B LAMA1 SLFN14 THBS2 LRP1 ABCB11

1.37e-0516713863e3d8f6df2feefafad5b44ba0ebf5b5a0fe4ed58
ToppCellfacs-Heart-RV-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6B LAMA1 SLFN14 THBS2 LRP1 ABCB11

1.37e-0516713863ad9f3122dbe96580f640388ef920ea209fc2349
ToppCellfacs-Aorta-Heart-3m-Endothelial-endocardial_endothelial_cells|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL10 STAB2 SLC38A4 PAQR5 GRIA3 GJA5

1.37e-051671386a4a795751644b22af616335379e64ae95175180c
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPM6B COL28A1 KIF21A LAMA1 ANKRD53 PLP1

1.42e-051681386948d9e9972bd2a4b503d55fa69b70dd568a35a67
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 FAT3 SPTLC1 PLXNA4 ATP12A DNAH11

1.47e-05169138612bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell343B-Fibroblasts-Fibroblast-B_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CIDEB FAT4 YOD1 P2RX7 KIF2A PLP1

1.62e-051721386c6bc78fd63c9479a84ec0552b55c89750cad0fa5
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPM6B FRAS1 KIF21A P2RX7 PLPP2 PLP1

1.62e-051721386bc3ed05fdd94d5e1f19285aea867b1453292baec
ToppCell343B-Fibroblasts-Fibroblast-B_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CIDEB FAT4 YOD1 P2RX7 KIF2A PLP1

1.62e-051721386bfb87a281a9cf6ad45b310bf8104fc0ab382b549
ToppCellfacs-Heart-RV-18m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC37A1 CACNA1D BPI LMBR1L SLC2A6 CNR2

1.62e-0517213862dcc9d67d6ecc35940eabbc8ed528f5f884f6976
ToppCellfacs-Heart-RV-18m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC37A1 CACNA1D BPI LMBR1L SLC2A6 CNR2

1.62e-05172138664d2edbd8e2640b76225597883b1a524e6b1dd3b
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC16A9 TM9SF4 SPTLC1 KCNK15 BPIFB2 CNR2

1.67e-051731386e4d9a9a781acc531bc81c3fcee24d637e805c8e1
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1D FRAS1 GJD2 ANKRD53 PCNX1 SLC2A12

1.73e-051741386f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPM6B CACNA1D FAT3 GJA5 PLXNA4 LRP1

2.09e-05180138608ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1D FAT3 GRIA3 ODC1 PLXNA4 LRP1

2.30e-0518313867eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 FRAS1 STAB2 FAT3 LAMA1 DNAH11

2.37e-0518413862cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 FRAS1 STAB2 FAT3 LAMA1 DNAH11

2.37e-051841386ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 FRAS1 STAB2 FAT3 LAMA1 DNAH11

2.37e-0518413862b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Parm1|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

FRAS1 MAS1 GCNT4 ATP12A SORL1

2.49e-0511113851847dde68d349114286bc3317be6339666df4aa2
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RHCG FRAS1 SLC11A2 SLC38A4 NPC1L1 SORL1

2.59e-051871386b7689e7f6511920cd2beff27389555fddf685f61
ToppCellCOVID-19-kidney-DCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1D FRAS1 LAMA1 SLC19A3 PAQR5 TMEM101

2.67e-0518813861d56cd409793f05cca20757ab26e91f1a1ee67b5
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FRAS1 KIF21A LAMA1 SLC19A3 GCNT2 SORL1

2.75e-0518913865d9da836ce4308b8458bb3be3871a0aca734b6cd
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STAB2 ASAH2 SLC38A4 SLC19A3 APOLD1 ZMYND12

2.84e-051901386f50b9814a1beac67dc042a8c27dfd085ceeda3a6
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHCG MBOAT1 PAQR5 ARL15 ATP12A SLC16A7

2.84e-051901386c408d4033a130c0168159a5b6f286fd2b2a9a39d
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STAB2 ASAH2 SLC38A4 SLC19A3 APOLD1 ZMYND12

2.84e-051901386a22a510b4a257eb0eaf09c7ae7978d3d2f07a58c
ToppCell(5)_Fibroblasts-(5)_Fibroblast-C_(Myofibroblast)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

GPM6B CACNA1D FRAS1 FAT3 GJA5 SORL1

2.84e-05190138671e112dfb8c3190fe0286b45a046ea789eb6a8db
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHCG MBOAT1 PAQR5 ARL15 ATP12A SLC16A7

2.84e-051901386d4910c37045a8b8bb53b37625263bc0a47b6e3f8
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STAB2 ASAH2 SLC38A4 SLC19A3 APOLD1 ZMYND12

2.84e-05190138657c136bf6d7feafb4a220877bed0cc8fdf314db2
ToppCellLV-04._Ventricular_Cardiomyocyte_I|LV / Chamber and Cluster_Paper

KIF21A GCNT2 TENM2 AQP7 KCND3 SLC16A7

3.01e-051921386ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARHGAP42 FAT4 SLC16A9 FAT3 GRIA3 PLXNA4

3.01e-05192138672881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP42 CACNA1D FAT3 THBS2 PLXNA4 LRP1

3.01e-051921386162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP42 GPM6B CACNA1D FAT3 PLXNA4 LRP1

3.01e-0519213863d0cb19f037f604253d7d728689aeaa94251e92b
ToppCellLPS-IL1RA-Stromal_mesenchymal|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP42 CACNA1D FAT3 THBS2 PLXNA4 LRP1

3.01e-0519213864e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCellBronchial-10x5prime-Stromal-Schwann-Schwann_nonmyelinating|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

GPM6B SLC22A15 SLC19A1 PLXNA4 PLP1

3.08e-051161385b0a3c109c5f20ab699e53bf8ab3903d102f5f315
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPM6B CACNA1D FAT3 GRIA3 GJA5 LRP1

3.10e-0519313864c74a3f69b2cbdf139e7e66b44bd86869ac34dc0
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPM6B CACNA1D FAT3 GRIA3 GJA5 LRP1

3.10e-051931386ff8ceeb3cfd1bef7239df490c19d181091750833
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GPM6B ABCA2 SLC7A14 PLPP2 KCND3 PLP1

3.10e-051931386947200ef6c3a2e35ad7e6b4af29d92384bdf73f5
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

CACNA1D FAT4 FRAS1 FAT3 TENM2 GJA5

3.10e-051931386acad568621ed677031797b8c2e34dafea798d681
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RHCG FRAS1 SLC38A4 ARL15 GCNT4 ATP12A

3.10e-051931386d994b2f2707877288f88cab7cd6002ef91962c50
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 SLC11A2 SLC38A4 GCNT4 ATP12A SORL1

3.10e-0519313865da60321bcf761913eb30779b6d8b1e933c5e51e
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLC11A2 SLC22A15 P2RX7 SLC22A16 LRP1 SLC26A11

3.28e-0519513869d649ac7d2af313481069c95349efc0c68449e2b
ToppCelldistal-Hematologic-Classical_Monocyte-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NUP214 MEFV SLC2A3 BPI USP15 SORL1

3.28e-05195138632c34741e35006b7238896fd04a497011297dd22
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ARHGAP42 CACNA1D FAT4 FAT3 PAQR5 TENM2

3.28e-0519513860e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCellmyeloid-Monocyte-CD14+_Monocyte|myeloid / Lineage, cell class and subclass

SLC22A15 NUP214 SLC2A3 BPI LRP1 PCNX1

3.28e-05195138615ba9c5f6ecb6ae2c603e6b036eb92b00b46f13f
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC19A3 GCNT2 SLC7A14 TMEM101 SLC2A12 SLC16A7

3.28e-051951386a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARHGAP42 FAT4 OR5V1 FAT3 GRIA3 TENM2

3.28e-051951386f5e91ce20a7ce528dc4c1a968c7bf096bf45c528
ToppCell367C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

GPM6B CACNA1D FRAS1 FAT3 GJA5 SORL1

3.38e-0519613866730743cf088c419ccc2d28765769fc09d3ba6a7
ToppCell367C-Fibroblasts-Fibroblast-C_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

GPM6B CACNA1D FRAS1 FAT3 GJA5 SORL1

3.38e-05196138621dab89f3699037138a9c7a0e4dc98739a9fad9c
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPM6B FRAS1 COL28A1 KIF21A P2RX7 PLP1

3.47e-051971386bb35a2b7320fda92e9cd42f536b7bd54e3a73a32
ToppCellfacs-Brain_Non-Myeloid|facs / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6B KIF21A TOB1 APOLD1 PLP1 SLC38A3

3.47e-051971386a1f7eec1aca03432caa8fe817ff6d24b29d4062d
ToppCellCOVID-19-lung-Macrophage_VCANhi_FCN1hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

TCIRG1 MEFV SLC2A3 P2RX7 USP15 SORL1

3.57e-051981386ea34096bee852a7e996f097fa279381afa8f86ff
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ARHGAP42 FAT4 GRIA3 PLXNA4 LRP1 PLP1

3.67e-05199138638cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPM6B FRAS1 COL28A1 KIF21A LAMA1 PLP1

3.67e-051991386a76aa30fb264bdcbc0cb09113f814fc5a89e7319
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPM6B FRAS1 COL28A1 KIF21A P2RX7 PLP1

3.67e-0519913861761669ec514fdb4175042f11b9a31fa5687fc2b
ToppCellLPS_anti-TNF-Hematopoietic_Erythro-Megakary-Erythro-Mega-Platelets|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SLC37A1 SPCS1 ODC1 YOD1 UGP2 KIF2A

3.78e-052001386e4be88bcef2738915f711b32c95e9c613e7edf96
ToppCellBronchial-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1D FAT4 FAT3 THBS2 KCND2 LRP1

3.78e-052001386cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RHCG FRAS1 TMEM114 KCND1 ATP12A

8.35e-051431385990844ca674d30b2924c74b45bed4fdfb8463fa7
ToppCellCOVID-19-Heart-Adipocyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

GPM6B SLC19A3 AQP7 KCND2 PLXNA4

1.15e-04153138593958bd9c951222ba5b740d1cb83fd5d78a10e1e
ToppCellfacs-Liver-Hepatocytes|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A4 CLDN12 ABCB11 SLC16A7 SLC38A3

1.26e-041561385e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1D KIF27 MBOAT1 SLC19A3 REV1

1.26e-0415613854d2679e7639758c49fc25a2deb9109b08f0a3e57
ToppCelldroplet-Heart-nan-3m-Endothelial-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC37A1 SLC16A13 NUP214 AQP7 GJA5

1.29e-041571385d85a2f56ae313baa9738e81d2756ce1fe1ba50db
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL10 STAB2 GCNT4 TENM2 SLC2A12

1.33e-041581385f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL10 STAB2 GCNT4 TENM2 SLC2A12

1.33e-0415813858c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCellPND07-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC19A3 SLCO1B3 AK7 PLPP2 DNAH11

1.41e-041601385028b5261a1da832d52f66fb620db83e5fbbd874a
ToppCellPND07-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC19A3 SLCO1B3 AK7 PLPP2 DNAH11

1.41e-0416013851f4ee446436726c3d373f56d87dd80b6a12e8b9e
ToppCellPND01-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CIDEB ODC1 SLFN14 SLC2A3 PLXNA4

1.46e-04161138552556b89808e551540f33a13f57417a6696c2438
ToppCellPND01-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CIDEB ODC1 SLFN14 SLC2A3 PLXNA4

1.46e-04161138554f156cf2bd5a6ba9a78ec4e3ee28b89998aec2e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC19A3 AQP7 THBS2 KCND2 LRP1

1.46e-041611385a006491c991e6a134be20ad75092a91f3b7c3c91
ToppCellfacs-MAT-Fat-24m-Myeloid-myeloid_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCRL2 GCNT2 MEFV SLC2A6 SORL1

1.46e-04161138565888250b8c1da6a8f9b5376e086a3769a1cbbd8
ToppCellPND01-Immune-Immune_Myeloid-Megakaryocyte/Platelet|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CIDEB ODC1 SLFN14 SLC2A3 PLXNA4

1.46e-041611385242891be849a4398fe8bea44875ae1ba57950944
ToppCelldroplet-Fat-Gat|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCRL2 GCNT2 SLC2A3 SLC2A6 SORL1

1.59e-041641385c7ad946829c655038b33748dddd7d68c15489034
ToppCelldroplet-Fat-Gat-18m|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCRL2 GCNT2 SLC2A3 SLC2A6 SORL1

1.59e-0416413853aae702a23fbf1d36a6f18596c23e985581de815
ToppCelldroplet-Fat-Mat-18m-Myeloid-monocyte|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCRL2 GCNT2 SLC2A3 SLC2A6 SORL1

1.59e-041641385a27b9b3380f29bb17c9f787423f2591f2b9cf33e
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid-neutrophil|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GCNT2 SLC2A3 SLC2A6 PLP1 SORL1

1.59e-0416413858e6dbddacd56a07769163813e3ebfad13302bb62
ToppCellfacs-BAT-Fat-3m-Myeloid-myeloid_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCRL2 GCNT2 MEFV SLC2A6 SORL1

1.63e-041651385bfe330751d34813af7540765b490406078c40da7
ToppCellfacs-BAT-Fat-3m-Myeloid|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCRL2 GCNT2 MEFV SLC2A6 SORL1

1.63e-0416513858bdeacbb47948fabae2575689f811a9fad47f779
ToppCellfacs-Lung-3m-Hematologic-myeloid-neutrophil-neutrophil|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GCNT2 MEFV SLC2A3 SLC2A6 SORL1

1.68e-0416613853195035445d35d820f5e00dd03b029730478b024
ToppCellfacs-Spleen-nan-18m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPE FAT3 KIF4A SLFN14 MEFV

1.68e-0416613858d535fab019356894b4dad3fbdbc4d2ad3e16082
ToppCellfacs-Spleen-nan-18m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPE FAT3 KIF4A SLFN14 MEFV

1.68e-041661385f56b1c0d6cb5353a16a2598bda905287f16d2c39
ToppCellfacs-Lung-3m-Hematologic-myeloid-neutrophil|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GCNT2 MEFV SLC2A3 SLC2A6 SORL1

1.68e-0416613856b6ecd70264b6bfbd8a3a378c965702829e2ecf1
ToppCellfacs-Spleen-nan-18m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPE FAT3 KIF4A SLFN14 MEFV

1.68e-041661385a5074c96c6561273029aceb93402a7e038140f50
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RHCG MBOAT1 PAQR5 ARL15 TMEM101

1.73e-041671385edc5f04584b44f99ff9a62bbe0dab6fc044fb334
ToppCelldroplet-Marrow-BM-1m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC16A13 P2RX7 LRP1 SLC26A11 DNAH11

1.78e-0416813852e88d9cb7c80a4656fab290db8b45a5a0599d769
ToppCell(3)_MNP-(3)_DC_plasmacytoid|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)

GPM6B GRIA3 ANKRD53 PLXNA4 UXT

1.78e-04168138513c160ea1a19b47d2e7e2dae818c8dcde4e3e377
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PLPP2 KCNK15 BPIFB2 ATP12A CERS4

1.83e-041691385db73dae011ff3749b3706e50ab46d03b775dd6bb
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PLPP2 KCNK15 BPIFB2 ATP12A CERS4

1.83e-04169138597b7047b87ce0052d8580565c9b44fd2aa6f0d5c
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PLPP2 KCNK15 BPIFB2 ATP12A CERS4

1.83e-0416913851a684471dbda42e1470e5a889648666e14f25982
Drugsodium

CACNA1D SLC16A13 SLC38A4 SLC2A7 SPTLC1 SLC2A14 TCIRG1 SLCO1B3 GRIA3 ODC1 SLCO1B1 SLC7A14 SLC2A3 SLC7A8 P2RX7 SLC22A16 KCND2 KCND3 ABCB11 ATP12A SLC26A11 SLC2A12 SLC38A3

1.05e-0894413723CID000000923
DrugNSC-327434

SLC2A7 SLC2A14 SLC2A3 SLC2A12

8.62e-0881374CID000332025
DrugL-I TC

SLC2A7 SLC2A14 SLC2A3 SLC2A12

8.62e-0881374CID000129434
Drugheptanol

GJD2 TM9SF1 GRIA3 GJA5 P2RX7 KCND2

1.87e-07421376CID000008129
Drugethylidene glucose

SLC2A7 SLC2A14 SLC2A3 SLC2A12

4.01e-07111374CID000093075
DrugIAPS-forskolin

SLC2A7 SLC2A14 SLC2A3 SLC2A12

5.98e-07121374CID000163853
Drugrifamycin SV

SLCO1B3 SLCO1B1 ABCB11

8.49e-0741373ctd:C023808
Drugsodium chloride

GPM6B MAN2B2 SLC2A7 SLC2A14 TCIRG1 MANEA GCNT2 HM13 SLC2A3 STT3B RHO PLPP2 SLC2A6 UGP2 SLC2A12 ALG6 M6PR PAQR7 HSP90AA2P

1.09e-0686513719CID000000206
DrugATB-BMPA

SLC2A7 SLC2A14 SLC2A3 SLC2A12

1.20e-06141374CID000122117
Drug3-iodothyronamine

RHCG SLC37A1 SLC7A14 SLC26A11 SLC16A7

1.52e-06331375ctd:C487948
Drug4,6-O-ethylidene-D-glucose

SLC2A7 SLC2A14 SLC2A3 SLC2A12

2.16e-06161374CID000114511
DrugPCMBS

SLC37A1 SLC2A7 SLC2A14 AQP7 SLC2A3 SLC2A12 SLC16A7

3.41e-061051377CID000011136
DrugT 1095

SLC2A7 SLC2A14 SLC2A3 SLC2A12

5.64e-06201374CID006918410
Drugthiazolidinedione

ABCA2 SLC2A7 SLC2A14 SLCO1B3 SSTR5 SLCO1B1 AQP7 SLC2A3 ABCB11 SLC2A12

6.48e-0627413710CID000005437
Drugoctylglucopyranoside

RHCG SLC2A7 TM9SF1 SLC2A14 AQP7 SLC2A3 RHO SLC2A12

6.64e-061631378CID000062080
Drugirbesartan

CACNA1D GJA5 KCND2 KCND3 ABCB11

7.38e-06451375ctd:C081309
Drugphlorizine

CACNA1D SLC2A7 SLC2A14 AQP7 SLC2A3 SLC2A12

8.24e-06791376CID000004789
DrugTAK-875

SLCO1B3 SLCO1B1 ABCB11

1.17e-0581373ctd:C557331
DrugFusidic Acid

SLCO1B3 SLCO1B1 ABCB11

1.17e-0581373ctd:D005672
DrugTetracycline

CIDEB ERCC4 MAN2B2 MAT2B SPTLC1 SLCO1B3 ODC1 SLC2A3 RHO KCNK15 NPC1L1 ABCB11 SLC16A7 PAQR7 SORL1

1.25e-0566813715ctd:D013752
Drugphloretin

CACNA1D SLC2A7 SLC2A14 AQP7 SLC2A3 SLC2A12 SLC16A7

1.47e-051311377CID000004788
DrugMan5GlcNAc2

MAN2B2 MANEA GCNT2 ZP2 ALG6

2.00e-05551375CID003081562
Drug3-O-methyl-alpha-D-glucopyranose

SLC2A7 SLC2A14 ODC1 SLC2A3 SLC2A12

2.39e-05571375CID000083246
DrugDequalinium dichloride [522-51-0]; Down 200; 7.6uM; PC3; HT_HG-U133A

GPM6B SLC11A2 TM9SF4 TCIRG1 SLC19A1 PCNX1 USP15 MAP2K5

2.63e-0519713786296_DN
Drugrubidium

SLC11A2 P2RX7 KCND2 ATP12A CERS4

3.33e-05611375CID000105153
Drugrepaglinide

SLCO1B3 SLCO1B1 ABCB11

3.39e-05111373ctd:C072379
Drugpotassium

RHCG CACNA1D GJD2 SLC38A4 TCIRG1 ODC1 SLC7A8 TOB1 P2RX7 KCND1 KCND2 KCND3 KCNK15 CLPTM1 KCNS1 ATP12A SLC38A3 CERS4

3.56e-05100813718CID000000813
Drug(5-(3-(4-(2-bromo-5-fluorophenoxy)piperidin-1-yl)isoxazol-5-yl)-2H-tetrazol-2-yl)acetic acid

SLCO1B3 SLCO1B1

3.59e-0521372ctd:C561635
Drug3-OMG

SLC2A7 SLC2A14 SLC2A3 SLC2A12

4.48e-05331374CID000097217
Drugglimepiride

SLCO1B3 SLCO1B1 ABCB11

4.51e-05121373ctd:C057619
Drugchromium picolinate

SLC2A7 SLC2A14 SLC2A3 SLC2A12

5.06e-05341374CID000151932
DrugNSC740136

SLC2A7 SLC2A14 SLCO1B3 SLCO1B1 SLC2A3 SLC2A12

5.18e-051091376CID000003706
DrugPhalloidine

SLCO1B3 SLCO1B1 ABCB11

5.83e-05131373ctd:D010590
DrugHNCs

SLC2A14 HM13 SLC2A3

7.39e-05141373CID000062481
Drugandrost-5-en-17-one

PLPP2 M6PR SLC38A3

7.39e-05141373CID000151432
Drug3-O-methyl-D-glucose

GJD2 SLC2A7 SLC2A14 SLC2A3 SLC2A12

7.42e-05721375CID000008973
DrugZidovudine

SLC37A1 SLC38A4 SLC22A15 SLC2A14 SLC19A3 SLC2A3 SLC30A7 SLC7A8 SLC2A6 ABCB11 SLC26A11 SLC38A3

7.58e-0552113712ctd:D015215
DrugRubidium chromate

P2RX7 KCND1 KCND2 ATP12A CERS4

8.46e-05741375CID000061605
Drugbutamben

KCND1 KCND2 KCND3

9.20e-05151373CID000002482
DrugCephalothin

SLCO1B3 NPC1L1 ABCB11

9.20e-05151373ctd:D002512
Drugdolichols

MAN2B2 MANEA GCNT2 STT3B UGP2 ALG6

9.70e-051221376CID000439223
Drug6-o-phosphonohexose

SLC2A7 SLC2A14 AK7 SLC2A3 SLC2A12 M6PR CNR2

1.32e-041851377CID000099058
Diseasearachidonoylcarnitine (C20:4) measurement

SLC16A9 SLCO1B1 SLC22A16

2.00e-05121353EFO_0800544
DiseaseHYPERBILIRUBINEMIA, ROTOR TYPE, DIGENIC

SLCO1B3 SLCO1B1

2.08e-0521352C4016905
DiseaseRotor Syndrome

SLCO1B3 SLCO1B1

2.08e-0521352C0220991
DiseaseRotor syndrome

SLCO1B3 SLCO1B1

2.08e-0521352cv:C0220991
DiseaseHYPERBILIRUBINEMIA, ROTOR TYPE

SLCO1B3 SLCO1B1

2.08e-0521352237450
Diseasedihomo-linolenoylcarnitine (C20:3n3 or 6) measurement

SLC16A9 SLCO1B1 SLC22A16

2.59e-05131353EFO_0800547
Diseaseglycochenodeoxycholate glucuronide (1) measurement

SLCO1B3 SLCO1B1 SLC25A28

2.59e-05131353EFO_0800474
Diseasedihomo-linoleoylcarnitine (C20:2) measurement

SLCO1B1 SLC22A16

6.21e-0531352EFO_0800546
Diseasehypokalemia (biomarker_via_orthology)

RHCG ATP12A

6.21e-0531352DOID:4500 (biomarker_via_orthology)
DiseaseColorectal Carcinoma

SLC11A2 SLC22A15 LAMA1 SLCO1B3 ODC1 P2RX7 KCND3 SLC19A1 LRP1 ABCB11 BPIFB2 SORL1

9.64e-0570213512C0009402
Diseaseceramide measurement

SPTLC1 SLCO1B3 ARL15 SLCO1B1 PLXNA4 M6PR CERS4

1.08e-042351357EFO_0010222
Diseaseuric acid measurement

FAT4 FRAS1 SLC16A9 FAT3 GCNT2 ARL15 SLCO1B1 TENM2 AK7 MFSD12 CERS4

1.19e-0461013511EFO_0004761
Diseaseurate measurement, bone density

RHCG FRAS1 ERCC4 MBOAT1 TENM2 SLC7A8 APOLD1 PLXNA4 SLC2A12 SLC38A3 DNAH11

1.36e-0461913511EFO_0003923, EFO_0004531
Diseasemetabolic acidosis (biomarker_via_orthology)

RHCG SLC38A3

2.06e-0451352DOID:0050758 (biomarker_via_orthology)
Diseasebilirubin metabolic disorder (implicated_via_orthology)

SLCO1B3 SLCO1B1

2.06e-0451352DOID:2741 (implicated_via_orthology)
Diseasehereditary sensory neuropathy (implicated_via_orthology)

SCN11A SPTLC1

2.06e-0451352DOID:0050548 (implicated_via_orthology)
Diseaselinoleoylcarnitine (C18:2) measurement

SLC16A9 SLC22A16

2.06e-0451352EFO_0800338
Diseasebilirubin metabolic disorder (is_implicated_in)

SLCO1B3 SLCO1B1

3.08e-0461352DOID:2741 (is_implicated_in)
Diseaseclubfoot (implicated_via_orthology)

FRAS1 TCIRG1

3.08e-0461352DOID:11836 (implicated_via_orthology)
Diseasedeoxycholic acid glucuronide measurement

SLCO1B3 SLCO1B1

5.71e-0481352EFO_0800575
DiseaseSudden Cardiac Arrest

KCND2 KCND3

5.71e-0481352C1720824
Diseasethreonine measurement

SLC38A4 MANEA SLC7A8

6.49e-04371353EFO_0009775
Diseasesleep latency

FRAS1 ERCC4 SLC38A3

6.49e-04371353EFO_0005280
Diseasehexadecenedioate (C16:1-DC) measurement

SLCO1B3 SLCO1B1

7.32e-0491352EFO_0800562
Diseaseegg allergy measurement

ERCC4 ABCB11

7.32e-0491352EFO_0007018
DiseaseX-21467 measurement

SLCO1B3 SLCO1B1

7.32e-0491352EFO_0020007
Diseasesmoking behavior

CACNA1D ERCC4 TENM2 PLXNA4 MAP2K5 SLC38A3 SORL1

1.01e-033411357EFO_0004318
Diseasecholestasis (biomarker_via_orthology)

SLCO1B3 SLCO1B1 ABCB11

1.48e-03491353DOID:13580 (biomarker_via_orthology)
Diseasecataract (biomarker_via_orthology)

SLC2A14 SLC2A3

1.57e-03131352DOID:83 (biomarker_via_orthology)
DiseaseColorectal Neoplasms

SLC22A15 LAMA1 SLCO1B3 ODC1 SLC19A1 ABCB11

1.77e-032771356C0009404
DiseaseGerm Cell Cancer

ERCC4 SLC2A3

2.10e-03151352C0740345
DiseaseEmbryonal Neoplasm

ERCC4 SLC2A3

2.10e-03151352C0027654
DiseaseNeoplasms, Germ Cell and Embryonal

ERCC4 SLC2A3

2.10e-03151352C0027658
DiseaseGerm cell tumor

ERCC4 SLC2A3

2.10e-03151352C0205851
DiseaseNeoplasms, Embryonal and Mixed

ERCC4 SLC2A3

2.10e-03151352C0205852
DiseaseCancer, Embryonal

ERCC4 SLC2A3

2.10e-03151352C0751364
DiseaseCancer, Embryonal and Mixed

ERCC4 SLC2A3

2.10e-03151352C0751365
DiseaseSinus Node Dysfunction (disorder)

CACNA1D KCND3

2.10e-03151352C0428908
Diseaseadverse effect, response to xenobiotic stimulus

ABCA2 STAB2 LAMA1

2.53e-03591353EFO_0009658, GO_0009410
Diseasesmoking status measurement

CACNA1D ERCC4 MAT2B FAT3 SLFN14 TENM2 KCND2 RAB3GAP2 PLXNA4 QSER1 USP15 MAP2K5 SORL1

2.61e-03116013513EFO_0006527
Diseasediet measurement, HOMA-B

FAT3 PLXNA4

3.38e-03191352EFO_0004469, EFO_0008111
Diseasesensorineural hearing loss (implicated_via_orthology)

SLC7A14 SLC7A8

3.38e-03191352DOID:10003 (implicated_via_orthology)
Diseaseanorectal malformation

CIDEB THBS2

3.38e-03191352MONDO_0019938
Diseasehydrocephalus (implicated_via_orthology)

KIF27 AK7

3.38e-03191352DOID:10908 (implicated_via_orthology)
Diseasefatty acid measurement

KIF27 SPCS1 MAS1 GCNT4 SLCO1B1 CLPTM1 PLXNA4

4.02e-034361357EFO_0005110
DiseaseHbA1c measurement, response to sulfonylurea

SLC16A9 SLCO1B1

4.12e-03211352EFO_0004541, EFO_0007922
Diseasedepressive disorder (implicated_via_orthology)

GPM6B PLP1

4.52e-03221352DOID:1596 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
LIGLYFVGLYSETFF

CCRL2

106

O00421
LFYLSSFVGGLSVLY

CERS4

141

Q9HA82
YYQGSQGVIFVLDSA

ARL15

96

Q9NXU5
VGIFLDYETGEISFY

BTN3A3

461

O00478
IGFLVGQYFLYGFSV

GJD2

211

Q9UKL4
YGHFQYNSVSLGFAL

ALG6

161

Q9Y672
VAYSFVVFENVALGY

FAT4

796

Q6V0I7
GFFNYLTYFLAAGAV

C1orf185

6

Q5T7R7
DGKIVYSYFIGLFSS

DNAH11

2226

Q96DT5
FASYYAGIAVAVLIT

ABCB11

141

O95342
LFIAFLFSGIIYTYG

CNR2

196

P34972
SYYRNSVGGFLVFDI

RAB39A

81

Q14964
GQREFAATNSYLGYF

QSER1

1401

Q2KHR3
VPYASVAFYIFTHQG

RHO

266

P08100
VIGILSAYISNYAFA

SLC2A12

176

Q8TD20
YFLDYGAVNLFSLGS

PAQR5

116

Q9NXK6
LFTSVYYVVEGGVLN

YOD1

161

Q5VVQ6
VGFINYLFYGVTVAG

SLC7A8

391

Q9UHI5
SIALYNSVYFIVFFG

APOLD1

191

Q96LR9
IGSYYQLFAAAVGNV

ANKRD53

106

Q8N9V6
IVVGFTSGYVRFYTE

RAB3GAP2

156

Q9H2M9
NIYFLFFSYGIVVGL

SLC16A9

101

Q7RTY1
LDYVGVAVYQFGSAL

PAQR7

141

Q86WK9
LVFYYVTGFFIAVSV

KCND1

186

Q9NSA2
LALVFYYVTGFFIAV

KCND3

181

Q9UK17
YYVTGFFIAVSVITN

KCND3

186

Q9UK17
STFTYQDILAGLVGY

FRAS1

2026

Q86XX4
TFLFGYNTGLYLLTA

MAS1

111

P04201
AVGAFLIYISSDYVF

MAT2B

126

Q9NZL9
AFGSAFQYGYNLSVV

SLC2A7

31

Q6PXP3
YYCFITLTTIGFGDF

KCNK15

191

Q9H427
YFGTAYVALTRDFAN

GCNT2

261

Q8N0V5
GFIYFADTTSYLIGR

LRP1

571

Q07954
HSGPAGYFQYTVFVI

ASAH2

196

Q9NR71
GYFQYTVFVIASEGF

ASAH2

201

Q9NR71
QALGAFLVYFTVYAQ

ATP12A

876

P54707
CSQFSRGVYAIFGFY

GRIA3

91

P42263
YTAVFGAYTAFLFIR

RCE1

236

Q9Y256
SLIEGYNATVFAYGQ

KIF27

71

Q86VH2
LYTLVGFVGFVTHYV

PCNX1

1296

Q96RV3
YGFSSGNFVYFLTLQ

PLXNA4

246

Q9HCM2
SSYIIGFYGAFFVEN

MAP2K5

221

Q13163
AFRTVYQVGGVTAYF

SLC25A28

311

Q96A46
VFYYVTGFFIAVSVI

KCND2

186

Q9NZV8
DYTSLVLYAVFFGLG

SLC16A7

336

O60669
TYVFAIVYAAADGTL

NUP214

251

P35658
AAVVSVAYLGFVFYL

SLC11A2

511

P49281
FYTSFAAYIFGLGLT

HM13

291

Q8TCT9
LYLAVGVSVFSGVAY

KCNS1

381

Q96KK3
FVDYRVGSISFYNVT

MEFV

721

O15553
YSLFYTAILHFSGGQ

AQP7

131

O14520
TSTYLVAFVVGEYDF

NPEPPSL1

241

A6NEC2
YVAAVYKVLGTFLFG

PLPP2

91

O43688
YGIILLAEGFYTTSA

GPM6B

101

Q13491
LSGINAVFYYSTGIF

SLC2A14

306

Q8TDB8
AVFYYSTGIFKDAGV

SLC2A14

311

Q8TDB8
VLGNFSFGYALVYTS

SLC2A6

46

Q9UGQ3
DILQSGFDGIYTYFA

MANEA

311

Q5SRI9
LFYGTVIAVYFQATS

OR1K1

251

Q8NGR3
IKDISGASFAGFYYI

GID4

246

Q8IVV7
AIVFLFYGSAIFTYV

OR5V1

246

Q9UGF6
SVFSLFYGTAFGVYI

OR7G1

246

Q8NGA0
FYGTAFGVYISSAVA

OR7G1

251

Q8NGA0
VGAPVYFVTTLGYNF

NPC1L1

896

Q9UHC9
QVYATFFEIYSGKVF

KIF2A

361

O00139
YIGSTLSYFGLAAVF

P2RX7

336

Q99572
TALFGLGYFYNIHSF

SLC37A1

141

P57057
VSVQGIIVYRASYFG

SLC25A31

191

Q9H0C2
FYLTQSFRFGVEIAY

FBH1

696

Q8NFZ0
VYIIGGFDSVDYFNS

KLHL10

341

Q6JEL2
GYFTFANLTFYEVRA

LACTBL1

386

A8MY62
LIGQGTFSYYAISNA

COL28A1

126

Q2UY09
GSAYFVLSQAFVKYI

GCNT4

301

Q9P109
YLGLSDYFFNTAGLV

BPI

286

P17213
GFIVGQYFIYGIFLT

GJA5

166

P36382
GTYGQISYAIINDFA

FAT3

2526

Q8TDW7
TAFGLGSKYFALYEV

ABCA2

856

Q9BZC7
IYIFHYGILTTDFSG

MBOAT1

126

Q6ZNC8
LGVSVQYATLGDYFR

MAN2B2

316

Q9Y2E5
QLSGINAVFYYSTGI

SLC2A3

281

P11169
NAVFYYSTGIFKDAG

SLC2A3

286

P11169
VFKGYNATVLAYGQT

KIF4A

76

O95239
IGQFSVGFYSAYSVA

HSP90AA4P

71

Q58FG1
FDYAVYVTIASAGGL

CLDN12

171

P56749
FFAVGIAQYALLGYF

SLC22A15

206

Q8IZD6
SIQFLVYGSYFAVIA

SLC19A3

436

Q9BZV2
YAFTVVANITVYGAA

MFSD12

171

Q6NUT3
NTILGYFDYAFTAIF

CACNA1D

916

Q01668
IDSAIQGYNGTIFAY

CENPE

71

Q02224
GRYYVASAFTLAVNI

ODC1

276

P11926
IGQFGVSFYSAYLVA

HSP90AA2P

131

Q14568
SVVVLFYGTAIAVYF

OR1C1

246

Q15619
RNVVYGIFYATSFLD

SORL1

1866

Q92673
YVSAFANTQGGYVLI

SLFN14

231

P0C7P3
AALFGYLTFYNGVES

SLC38A3

336

Q99624
IDILIFYGTFSYEFG

TMEM150A

216

Q86TG1
GNFYIVFLYNAAFAG

LMBR1L

431

Q6UX01
LSFLQGLFTFYHEGY

ARHGAP42

201

A6NI28
KFAIGAAFGLIYLYT

SLC22A16

451

Q86VW1
IASTYVYGFTVGLVQ

OR5AL1

161

P0C617
TAFGGFLKYTVSYDI

LAMA1

581

P25391
FIITAATVGYFIFYS

RNF128

216

Q8TEB7
VYGLSDAVVSVGFEY

TENM2

1136

Q9NT68
LAALFGYLTFYGEVE

SLC38A4

381

Q969I6
ASAGLYFFVVILSYA

SSTR5

281

P35346
LLQVSSYIGAFTYVF

SLCO1B1

346

Q9Y6L6
AYGGAFYAFVTAEKL

L3HYPDH

186

Q96EM0
AIIYSYGFATIASAI

SPTLC1

161

O15269
IFVYEGYVVISSGLF

BPIFB2

441

Q8N4F0
LFGSLNVKATFYGLY

CIDEB

146

Q9UHD4
NGSIYIHVYFTKSGF

CLPTM1

161

O96005
KFENGAFTYYGVSAL

CNNM3

576

Q8NE01
TYSYVTVGEFVAFFI

SLC7A14

121

Q8TBB6
IYASFYNSGLLDTFI

UGP2

226

Q16851
TSRIYVALGYGFFLE

UXT

86

Q9UBK9
NFLVSGGSAFYVLVY

TM9SF4

571

Q92544
FASLVAVYVVGGFLY

M6PR

196

P20645
GYLRDVTGNYTASFV

SLC16A13

361

Q7RTY0
STIFSGVAIYVNGYT

REV1

46

Q9UBZ9
ALVAYSFEVTGYQPF

SLC26A11

256

Q86WA9
CFEGYNATVFAYGQT

KIF21A

76

Q7Z4S6
VFVALYAISAVYFAG

STT3B

441

Q8TCJ2
YAAFVLFRGSYQFLV

SLC19A1

366

P41440
YNSVFFGRVYLGLSI

SLCO1B3

616

Q9NPD5
YVLFYQRQDTFSGTG

USP15

926

Q9Y4E8
LFSAIVGFIYGYVAE

SPCS1

96

Q9Y6A9
VTGAVALAAYSYFRI

STAB2

2471

Q8WWQ8
LAGISVYIAYSAAAF

TMEM114

151

B3SHH9
TFGAYFGLTVTRILY

RHCG

186

Q9UBD6
LQYSNAFDVFAAYGG

TOB1

301

P50616
FSYGYVRAEVLAGFV

SLC30A7

96

Q8NEW0
IRTSGGYFHLANIFY

ZMYND12

211

Q9H0C1
QGTQVVFLTGFGYVY

VPS13B

3336

Q7Z7G8
GAILVITATFLYGYD

SLC35A3

301

Q9Y2D2
NSLGYIYFVVFIIFG

SCN11A

1281

Q9UI33
SRYEVYTQGGVIFAT

ERCC4

96

Q92889
GFVFGYQSSSRFYVV

THBS2

1026

P35442
QYLRYVASAVFGVIG

WDR3

6

Q9UNX4
AAFAGVVATLGFIYY

ZP2

721

Q05996
GSQVYVTFAVSFYLV

TMEM127

166

O75204
GLFSIYTGFIYNECF

TCIRG1

451

Q13488
TVEFFGYSLLTGYVF

TM9SF1

566

O15321
ALAFLSGYYVTLAAQ

TMEM101

191

Q96IK0
FAGLYQVAQATFVYV

TMPPE

411

Q6ZT21
KFAAYVVAAGLQYGA

AK7

206

Q96M32
VIYGTASFFFLYGAL

PLP1

71

P60201