| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | RNA polymerase I general transcription initiation factor activity | 3.05e-04 | 9 | 59 | 2 | GO:0001181 | |
| GeneOntologyMolecularFunction | RNA polymerase I core promoter sequence-specific DNA binding | 4.64e-04 | 11 | 59 | 2 | GO:0001164 | |
| GeneOntologyMolecularFunction | semaphorin receptor activity | 5.56e-04 | 12 | 59 | 2 | GO:0017154 | |
| GeneOntologyMolecularFunction | RNA polymerase I transcription regulatory region sequence-specific DNA binding | 6.56e-04 | 13 | 59 | 2 | GO:0001163 | |
| GeneOntologyBiologicalProcess | olfactory nerve formation | 7.77e-06 | 2 | 58 | 2 | GO:0021628 | |
| GeneOntologyBiologicalProcess | olfactory nerve morphogenesis | 2.33e-05 | 3 | 58 | 2 | GO:0021627 | |
| GeneOntologyBiologicalProcess | gonadotrophin-releasing hormone neuronal migration to the hypothalamus | 1.62e-04 | 7 | 58 | 2 | GO:0021828 | |
| GeneOntologyBiologicalProcess | hypothalamic tangential migration using cell-axon interactions | 1.62e-04 | 7 | 58 | 2 | GO:0021856 | |
| GeneOntologyBiologicalProcess | olfactory nerve development | 2.15e-04 | 8 | 58 | 2 | GO:0021553 | |
| GeneOntologyBiologicalProcess | hypothalamus cell migration | 2.76e-04 | 9 | 58 | 2 | GO:0021855 | |
| GeneOntologyBiologicalProcess | hypothalamus gonadotrophin-releasing hormone neuron differentiation | 2.76e-04 | 9 | 58 | 2 | GO:0021886 | |
| GeneOntologyBiologicalProcess | hypothalamus gonadotrophin-releasing hormone neuron development | 2.76e-04 | 9 | 58 | 2 | GO:0021888 | |
| Domain | - | 5.23e-05 | 333 | 55 | 7 | 2.130.10.10 | |
| Domain | WD40/YVTN_repeat-like_dom | 5.44e-05 | 335 | 55 | 7 | IPR015943 | |
| Domain | PSI | 1.13e-04 | 32 | 55 | 3 | PF01437 | |
| Domain | Plexin_repeat | 1.13e-04 | 32 | 55 | 3 | IPR002165 | |
| Domain | PSI | 2.94e-04 | 44 | 55 | 3 | IPR016201 | |
| Domain | Plexin_cytopl | 3.02e-04 | 9 | 55 | 2 | PF08337 | |
| Domain | Plexin_cytoplasmic_RasGAP_dom | 3.02e-04 | 9 | 55 | 2 | IPR013548 | |
| Domain | Plexin | 3.02e-04 | 9 | 55 | 2 | IPR031148 | |
| Domain | PSI | 3.35e-04 | 46 | 55 | 3 | SM00423 | |
| Domain | WD40 | 9.75e-04 | 259 | 55 | 5 | PF00400 | |
| Domain | WD40 | 1.14e-03 | 268 | 55 | 5 | SM00320 | |
| Domain | WD40_repeat | 1.21e-03 | 272 | 55 | 5 | IPR001680 | |
| Domain | WD_REPEATS_1 | 1.34e-03 | 278 | 55 | 5 | PS00678 | |
| Domain | WD_REPEATS_2 | 1.36e-03 | 279 | 55 | 5 | PS50082 | |
| Domain | WD_REPEATS_REGION | 1.36e-03 | 279 | 55 | 5 | PS50294 | |
| Domain | WD40_repeat_dom | 1.79e-03 | 297 | 55 | 5 | IPR017986 | |
| Domain | Ubiquitin-rel_dom | 2.10e-03 | 184 | 55 | 4 | IPR029071 | |
| Domain | IPT | 2.85e-03 | 27 | 55 | 2 | SM00429 | |
| Domain | Spectrin_repeat | 3.29e-03 | 29 | 55 | 2 | IPR002017 | |
| Domain | TIG | 3.75e-03 | 31 | 55 | 2 | PF01833 | |
| Domain | RA | 3.75e-03 | 31 | 55 | 2 | SM00314 | |
| Domain | Sema | 3.75e-03 | 31 | 55 | 2 | SM00630 | |
| Domain | Semap_dom | 3.75e-03 | 31 | 55 | 2 | IPR001627 | |
| Domain | Sema | 3.75e-03 | 31 | 55 | 2 | PF01403 | |
| Domain | SEMA | 3.75e-03 | 31 | 55 | 2 | PS51004 | |
| Domain | Spectrin/alpha-actinin | 3.99e-03 | 32 | 55 | 2 | IPR018159 | |
| Domain | IPT | 3.99e-03 | 32 | 55 | 2 | IPR002909 | |
| Domain | SPEC | 3.99e-03 | 32 | 55 | 2 | SM00150 | |
| Domain | RA | 5.31e-03 | 37 | 55 | 2 | PS50200 | |
| Domain | WHTH_DNA-bd_dom | 5.59e-03 | 242 | 55 | 4 | IPR011991 | |
| Domain | RA_dom | 6.18e-03 | 40 | 55 | 2 | IPR000159 | |
| Domain | HMG_box | 1.07e-02 | 53 | 55 | 2 | PF00505 | |
| Domain | Quinoprotein_ADH-like_supfam | 1.07e-02 | 53 | 55 | 2 | IPR011047 | |
| Domain | HMG_BOX_2 | 1.10e-02 | 54 | 55 | 2 | PS50118 | |
| Domain | HMG | 1.10e-02 | 54 | 55 | 2 | SM00398 | |
| Pathway | WP_DNA_IRDAMAGE_AND_CELLULAR_RESPONSE_VIA_ATR | 4.62e-05 | 81 | 35 | 4 | M39490 | |
| Pathway | REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION | 2.13e-04 | 9 | 35 | 2 | MM15030 | |
| Pathway | REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION | 5.35e-04 | 14 | 35 | 2 | MM15029 | |
| Pathway | REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION | 5.35e-04 | 14 | 35 | 2 | M7578 | |
| Pathway | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | 6.16e-04 | 15 | 35 | 2 | MM15031 | |
| Pathway | REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION | 7.03e-04 | 16 | 35 | 2 | M16498 | |
| Pathway | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | 7.03e-04 | 16 | 35 | 2 | M8245 | |
| Pathway | BIOCARTA_CCR3_PATHWAY | 9.97e-04 | 19 | 35 | 2 | MM1361 | |
| Pathway | BIOCARTA_CCR3_PATHWAY | 9.97e-04 | 19 | 35 | 2 | M9152 | |
| Pubmed | 9.07e-06 | 3 | 61 | 2 | 8806646 | ||
| Pubmed | GSK3-β Stimulates Claspin Degradation via β-TrCP Ubiquitin Ligase and Alters Cancer Cell Survival. | 9.07e-06 | 3 | 61 | 2 | 31362447 | |
| Pubmed | 9.07e-06 | 3 | 61 | 2 | 23910567 | ||
| Pubmed | Differential expression of plexin-A subfamily members in the mouse nervous system. | 9.07e-06 | 3 | 61 | 2 | 11241833 | |
| Pubmed | 9.07e-06 | 3 | 61 | 2 | 20138877 | ||
| Pubmed | CHD1 acts via the Hmgpi pathway to regulate mouse early embryogenesis. | 9.07e-06 | 3 | 61 | 2 | 26092847 | |
| Pubmed | 9.07e-06 | 3 | 61 | 2 | 27277682 | ||
| Pubmed | 1.81e-05 | 4 | 61 | 2 | 16885022 | ||
| Pubmed | 1.81e-05 | 4 | 61 | 2 | 16885021 | ||
| Pubmed | 1.81e-05 | 4 | 61 | 2 | 10725340 | ||
| Pubmed | 1.81e-05 | 4 | 61 | 2 | 11306810 | ||
| Pubmed | Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis. | 1.81e-05 | 4 | 61 | 2 | 19270156 | |
| Pubmed | PlexinA polymorphisms mediate the developmental trajectory of human corpus callosum microstructure. | 1.81e-05 | 4 | 61 | 2 | 25518740 | |
| Pubmed | A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor. | 1.81e-05 | 4 | 61 | 2 | 8570614 | |
| Pubmed | 3.02e-05 | 5 | 61 | 2 | 21478680 | ||
| Pubmed | 3.02e-05 | 5 | 61 | 2 | 25313870 | ||
| Pubmed | 4.52e-05 | 6 | 61 | 2 | 19915186 | ||
| Pubmed | Expression and function of semaphorin 3A and its receptors in human monocyte-derived macrophages. | 4.52e-05 | 6 | 61 | 2 | 19480842 | |
| Pubmed | Semaphorin-6A controls guidance of corticospinal tract axons at multiple choice points. | 6.32e-05 | 7 | 61 | 2 | 19063725 | |
| Pubmed | Increased proximal bifurcation of CA1 pyramidal apical dendrites in sema3A mutant mice. | 6.32e-05 | 7 | 61 | 2 | 19655386 | |
| Pubmed | Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors. | 6.32e-05 | 7 | 61 | 2 | 10520994 | |
| Pubmed | 8.42e-05 | 8 | 61 | 2 | 15661641 | ||
| Pubmed | Integration of opposing semaphorin guidance cues in cortical axons. | 8.42e-05 | 8 | 61 | 2 | 22368082 | |
| Pubmed | PlexinA2 and semaphorin signaling during cardiac neural crest development. | 1.08e-04 | 9 | 61 | 2 | 11688557 | |
| Pubmed | 1.08e-04 | 9 | 61 | 2 | 19909241 | ||
| Pubmed | 1.08e-04 | 9 | 61 | 2 | 19966799 | ||
| Pubmed | Cdh1 regulates cell cycle through modulating the claspin/Chk1 and the Rb/E2F1 pathways. | 1.08e-04 | 9 | 61 | 2 | 19477924 | |
| Pubmed | Plexin A3 and plexin A4 convey semaphorin signals during facial nerve development. | 1.35e-04 | 10 | 61 | 2 | 18804103 | |
| Pubmed | Semaphorin-5B Controls Spiral Ganglion Neuron Branch Refinement during Development. | 1.65e-04 | 11 | 61 | 2 | 31209173 | |
| Pubmed | 1.97e-04 | 12 | 61 | 2 | 25839327 | ||
| Pubmed | The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpoint. | 1.97e-04 | 12 | 61 | 2 | 18662541 | |
| Pubmed | 1.97e-04 | 12 | 61 | 2 | 31690636 | ||
| Pubmed | On and off retinal circuit assembly by divergent molecular mechanisms. | 1.97e-04 | 12 | 61 | 2 | 24179230 | |
| Pubmed | 1.97e-04 | 12 | 61 | 2 | 28407732 | ||
| Pubmed | Transmembrane semaphorin signalling controls laminar stratification in the mammalian retina. | 1.97e-04 | 12 | 61 | 2 | 21270798 | |
| Pubmed | 1.97e-04 | 12 | 61 | 2 | 23991118 | ||
| Pubmed | 1.97e-04 | 12 | 61 | 2 | 24785407 | ||
| Pubmed | 2.33e-04 | 13 | 61 | 2 | 11604131 | ||
| Pubmed | Functional assembly of accessory optic system circuitry critical for compensatory eye movements. | 2.33e-04 | 13 | 61 | 2 | 25959730 | |
| Pubmed | 2.33e-04 | 13 | 61 | 2 | 10520995 | ||
| Pubmed | Semaphorin3A, Neuropilin-1, and PlexinA1 are required for lymphatic valve formation. | 2.33e-04 | 13 | 61 | 2 | 22723296 | |
| Pubmed | A midline switch of receptor processing regulates commissural axon guidance in vertebrates. | 2.72e-04 | 14 | 61 | 2 | 20159958 | |
| Pubmed | CUL2LRR1 , TRAIP and p97 control CMG helicase disassembly in the mammalian cell cycle. | 3.13e-04 | 15 | 61 | 2 | 33590678 | |
| Pubmed | 3.13e-04 | 15 | 61 | 2 | 19436707 | ||
| Pubmed | Expression of the semaphorins Sema 3D and Sema 3F in the developing parathyroid and thymus. | 3.57e-04 | 16 | 61 | 2 | 18489001 | |
| Pubmed | 3.57e-04 | 16 | 61 | 2 | 17356169 | ||
| Pubmed | 4.05e-04 | 17 | 61 | 2 | 11683995 | ||
| Pubmed | Genome-wide association analysis of age-at-onset in Alzheimer's disease. | 4.05e-04 | 17 | 61 | 2 | 22005931 | |
| Pubmed | Semaphorin signaling facilitates cleft formation in the developing salivary gland. | 4.05e-04 | 17 | 61 | 2 | 17626059 | |
| Pubmed | Identification of proteins that may directly interact with human RPA. | 4.05e-04 | 17 | 61 | 2 | 20679368 | |
| Pubmed | Human claspin is a ring-shaped DNA-binding protein with high affinity to branched DNA structures. | 5.08e-04 | 19 | 61 | 2 | 15226314 | |
| Pubmed | Class 5 transmembrane semaphorins control selective Mammalian retinal lamination and function. | 6.22e-04 | 21 | 61 | 2 | 21835343 | |
| Pubmed | DNA-dependent phosphorylation of Chk1 and Claspin in a human cell-free system. | 6.83e-04 | 22 | 61 | 2 | 15707391 | |
| Pubmed | mTOR drives its own activation via SCF(βTrCP)-dependent degradation of the mTOR inhibitor DEPTOR. | 7.48e-04 | 23 | 61 | 2 | 22017875 | |
| Pubmed | A semaphorin code defines subpopulations of spinal motor neurons during mouse development. | 8.15e-04 | 24 | 61 | 2 | 15869472 | |
| Pubmed | A radial axis defined by semaphorin-to-neuropilin signaling controls pancreatic islet morphogenesis. | 8.15e-04 | 24 | 61 | 2 | 28893946 | |
| Pubmed | 1.11e-03 | 28 | 61 | 2 | 18617019 | ||
| Pubmed | 1.16e-03 | 117 | 61 | 3 | 17145500 | ||
| Pubmed | Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1. | 1.31e-03 | 270 | 61 | 4 | 24366813 | |
| Pubmed | Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery. | 1.45e-03 | 32 | 61 | 2 | 16964240 | |
| Pubmed | FBXO38 Ubiquitin Ligase Controls Centromere Integrity via ZXDA/B Stability. | 1.45e-03 | 32 | 61 | 2 | 35813202 | |
| Pubmed | Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. | 1.64e-03 | 34 | 61 | 2 | 12791985 | |
| Cytoband | 1p32.1 | 7.76e-05 | 10 | 61 | 2 | 1p32.1 | |
| Cytoband | 11q14.3 | 8.40e-04 | 32 | 61 | 2 | 11q14.3 | |
| Cytoband | 10q26.3 | 2.12e-03 | 51 | 61 | 2 | 10q26.3 | |
| Cytoband | 1p34.2 | 2.64e-03 | 57 | 61 | 2 | 1p34.2 | |
| GeneFamily | WD repeat domain containing | 1.05e-04 | 262 | 33 | 5 | 362 | |
| GeneFamily | Plexins | 1.15e-04 | 9 | 33 | 2 | 683 | |
| GeneFamily | Ras association domain family | 1.44e-04 | 10 | 33 | 2 | 1198 | |
| GeneFamily | WD repeat domain containing|DDB1 and CUL4 associated factors | 4.85e-04 | 18 | 33 | 2 | 498 | |
| Computational | Genes in the cancer module 397. | 2.54e-04 | 121 | 28 | 4 | MODULE_397 | |
| Drug | Felbinac [5728-52-9]; Down 200; 18.8uM; MCF7; HT_HG-U133A | 9.50e-06 | 196 | 57 | 6 | 5700_DN | |
| Drug | indomethacin, USP; Down 200; 100uM; MCF7; HG-U133A | 1.01e-05 | 198 | 57 | 6 | 453_DN | |
| Drug | Melatonin [73-31-4]; Up 200; 17.2uM; MCF7; HT_HG-U133A | 1.01e-05 | 198 | 57 | 6 | 5393_UP | |
| Disease | peripheral neuropathy, response to docetaxel trihydrate | 6.36e-04 | 19 | 58 | 2 | EFO_0003100, GO_1902519 | |
| Disease | alcoholic pancreatitis | 9.60e-04 | 98 | 58 | 3 | EFO_1002013 | |
| Disease | Malignant neoplasm of breast | 1.14e-03 | 1074 | 58 | 8 | C0006142 | |
| Disease | peptic ulcer disease | 1.93e-03 | 33 | 58 | 2 | MONDO_0004247 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| MNKSRWQSRRRHGRR | 1 | Q8WV16 | |
| REWQRFGVRMLRERA | 606 | Q9H981 | |
| RMVRTDSLWRGLAER | 231 | Q9Y297 | |
| REQMERRLRTWLERE | 626 | Q8IY63 | |
| WASLRRREMVRSGAR | 41 | Q49A88 | |
| RRKLRDWSLEQMVRG | 141 | Q8N0U7 | |
| QRWMRRRQEELAARE | 356 | A6NK89 | |
| RWNGRILQMLNRLRE | 481 | Q9H4I0 | |
| WGLRRPIRLQMQDDR | 61 | Q9H2L5 | |
| VRGWLERKRLQRVMT | 301 | A0A1B0GVH7 | |
| EAAPSRRWLERMRRT | 146 | Q8TAE7 | |
| WMRRPEQRQGRACIR | 291 | P26572 | |
| PQSRRRMKRVWDRAV | 451 | Q8NC56 | |
| RQNRRSGEVERLRMW | 206 | Q9ULI0 | |
| WQKLRATDQEMRRER | 1026 | Q96MR6 | |
| SCWASRRREQLLREM | 1306 | O75882 | |
| VMWRLFRRRDPQETR | 61 | P27539 | |
| LEWRQGRMARIILQD | 1556 | Q9UIW2 | |
| LEWRQGRMTRIILQD | 1531 | P51805 | |
| MCDRNGGRRLRQWLI | 1 | Q02556 | |
| RARVWEMLNRERTAR | 1536 | Q92817 | |
| RRVRENPRDTQLWMA | 316 | Q9H7Z3 | |
| ERRASTWQRNAMRRR | 576 | Q96JK2 | |
| MWGRRRKLRRLNDVT | 1 | A8MQ11 | |
| PWVRRRRQAEMGTQE | 431 | Q9BRS8 | |
| WRQEERLREQEGKMR | 296 | Q8N9W4 | |
| MRWLRPAGRRREQES | 1 | Q8IXW0 | |
| VNRALGRWRQRMLRA | 351 | O15297 | |
| MERGRERADTRRWRF | 56 | Q9ULW8 | |
| MAVRSLWAGRLRVQR | 1 | Q8TAA5 | |
| EQTMRRRQRREWEAR | 166 | O75419 | |
| VDRQNRRSNIMWLDR | 451 | O75054 | |
| HWEARRRQMALDRRR | 6 | A0A1B0GVQ3 | |
| ALQAMRAAIERRWRR | 401 | H7BZ55 | |
| RIEQMVARWLRRSRD | 16 | Q5SYB0 | |
| RRRVLRPVLSWMDRE | 36 | Q9H9V9 | |
| MDRRSRAQQWRRARH | 1 | O95467 | |
| RRRTWSRDEVMGDNL | 111 | Q96L14 | |
| MPWRRRRNRVSALEG | 1 | Q49MI3 | |
| WSLRRRQQLARQARM | 201 | Q9BXC0 | |
| GEEQSRGQWARRRRR | 91 | Q8WUQ7 | |
| ERCNIMRLVDRRWAG | 266 | Q5TDH0 | |
| RWVRLRRRDLSQMEA | 1041 | O75923 | |
| GDELHQRTMWRRRAR | 41 | O00198 | |
| RERKMQWVQRQRLER | 311 | Q8N490 | |
| RALQEWRERAQRMRK | 361 | Q9C0I9 | |
| RLEKEWMRNRSAARR | 251 | O95255 | |
| RMREEESQRLSWLRA | 661 | Q9UPV0 | |
| WGTERIGRRMKRQDQ | 61 | A8MTZ7 | |
| RIEREQWLRDMAQQG | 1176 | Q9HAW4 | |
| MDSLALGRWRQRRAE | 1 | A0A1B0GUT2 | |
| ERMVEIGRRWQRIPQ | 256 | P0CB48 | |
| SVRERMVEIGRRWQR | 246 | P0CB47 | |
| RLWDFLRQMVAARRE | 511 | O15020 | |
| MVTRWRRNEDGAICR | 1351 | O94759 | |
| RGIQRWMRNLREACR | 331 | P0DKB5 | |
| WNKALMENRRRSRQD | 601 | O15050 | |
| SWRRRVGTQMERVRE | 2691 | O15050 | |
| MLARRWQDRCLEVRE | 1011 | Q9Y4E6 | |
| VRGWMARRHFQRLRD | 871 | Q9ULV0 | |
| RMRRAEQLRRWRGSL | 16 | O60237 | |
| QSMRTRRRRVRDPWG | 496 | Q5VVJ2 |