Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	histone H3K9 methyltransferase activity	PRDM2 ASH1L	1.36e-04	13	27	2	GO:0046974
GeneOntologyMolecularFunction	chromatin binding	KDM3B CHD8 MACROH2A2 STAG2 TOP2B ASH1L	3.83e-04	739	27	6	GO:0003682
GeneOntologyMolecularFunction	ATP-dependent activity, acting on DNA	CHD8 RFC1 TOP2B	6.57e-04	127	27	3	GO:0008094
GeneOntologyMolecularFunction	histone H3 methyltransferase activity	PRDM2 ASH1L	1.61e-03	44	27	2	GO:0140938
GeneOntologyMolecularFunction	histone modifying activity	KDM3B PRDM2 ASH1L	3.55e-03	229	27	3	GO:0140993
GeneOntologyMolecularFunction	protein-lysine N-methyltransferase activity	PRDM2 ASH1L	3.80e-03	68	27	2	GO:0016279
GeneOntologyMolecularFunction	lysine N-methyltransferase activity	PRDM2 ASH1L	3.91e-03	69	27	2	GO:0016278
GeneOntologyMolecularFunction	histone methyltransferase activity	PRDM2 ASH1L	4.13e-03	71	27	2	GO:0042054
GeneOntologyMolecularFunction	catalytic activity, acting on DNA	CHD8 RFC1 TOP2B	5.18e-03	262	27	3	GO:0140097
GeneOntologyBiologicalProcess	sister chromatid cohesion	PDS5B STAG2 MEIKIN	1.01e-04	67	28	3	GO:0007062
GeneOntologyBiologicalProcess	negative regulation of protein depolymerization	MAP1B ADD2 ADD3	2.35e-04	89	28	3	GO:1901880
GeneOntologyBiologicalProcess	regulation of protein polymerization	CCL21 MAP1B ADD2 ADD3	2.54e-04	231	28	4	GO:0032271
GeneOntologyBiologicalProcess	chromosome organization	PDS5B CHD8 RFC1 STAG2 TOP2B MEIKIN	2.67e-04	686	28	6	GO:0051276
GeneOntologyBiologicalProcess	negative regulation of protein-containing complex disassembly	MAP1B ADD2 ADD3	3.32e-04	100	28	3	GO:0043242
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase III	CHD8 ELL	3.33e-04	20	28	2	GO:0045945
GeneOntologyBiologicalProcess	regulation of protein depolymerization	MAP1B ADD2 ADD3	3.83e-04	105	28	3	GO:1901879
GeneOntologyBiologicalProcess	chromatin remodeling	KDM3B CHD8 MACROH2A2 IFI16 PRDM2 ASH1L	4.03e-04	741	28	6	GO:0006338
HumanPheno	Delayed speech and language development	KDM3B CHD8 RFC1 MAP1B STAG2 NEXMIF ADD3 ASH1L	5.47e-06	1123	8	8	HP:0000750
HumanPheno	Language impairment	KDM3B CHD8 RFC1 MAP1B STAG2 NEXMIF ADD3 ASH1L	8.03e-06	1178	8	8	HP:0002463
HumanPheno	Hyperactivity	KDM3B CHD8 MAP1B STAG2 NEXMIF ASH1L	3.89e-05	558	8	6	HP:0000752
HumanPheno	Pica	CHD8 ASH1L	6.02e-05	8	8	2	HP:0011856
HumanPheno	Autistic behavior	KDM3B CHD8 MAP1B STAG2 NEXMIF ASH1L	1.20e-04	678	8	6	HP:0000729
HumanPheno	Attention deficit hyperactivity disorder	KDM3B CHD8 MAP1B STAG2 NEXMIF	1.56e-04	413	8	5	HP:0007018
HumanPheno	Diagnostic behavioral phenotype	KDM3B CHD8 MAP1B STAG2 NEXMIF ASH1L	2.10e-04	747	8	6	HP:0025783
HumanPheno	Abnormality of upper lip vermillion	KDM3B CHD8 MAP1B STAG2 NEXMIF	2.73e-04	464	8	5	HP:0011339
HumanPheno	Abnormal response to social norms	KDM3B CHD8 MAP1B STAG2 NEXMIF ASH1L	3.26e-04	807	8	6	HP:5200123
HumanPheno	Social disinhibition	KDM3B CHD8 MAP1B STAG2 NEXMIF ASH1L	3.26e-04	807	8	6	HP:5200029
HumanPheno	Disinhibition	KDM3B CHD8 MAP1B STAG2 NEXMIF ASH1L	3.26e-04	807	8	6	HP:0000734
HumanPheno	Inappropriate behavior	KDM3B CHD8 MAP1B STAG2 NEXMIF ASH1L	3.26e-04	807	8	6	HP:0000719
HumanPheno	Short attention span	KDM3B CHD8 MAP1B STAG2 NEXMIF	4.56e-04	517	8	5	HP:0000736
HumanPheno	Reduced attention regulation	KDM3B CHD8 MAP1B STAG2 NEXMIF	4.95e-04	526	8	5	HP:5200044
HumanPheno	Abnormally increased volition	KDM3B CHD8 MAP1B STAG2 NEXMIF ASH1L	4.97e-04	869	8	6	HP:5200263
HumanPheno	Abnormal social development	KDM3B CHD8 MAP1B STAG2 NEXMIF ASH1L	6.38e-04	908	8	6	HP:0025732
HumanPheno	Open mouth	CHD8 NEXMIF ASH1L	7.21e-04	124	8	3	HP:0000194
HumanPheno	Abnormal eating behavior	CHD8 NEXMIF ASH1L	7.91e-04	128	8	3	HP:0100738
HumanPheno	Sleep abnormality	CHD8 RFC1 STAG2 NEXMIF ASH1L	8.92e-04	596	8	5	HP:0002360
HumanPheno	Recurrent hand flapping	CHD8 NEXMIF	9.19e-04	30	8	2	HP:0100023
HumanPheno	Abnormal upper lip morphology	KDM3B CHD8 MAP1B STAG2 NEXMIF ASH1L	9.80e-04	980	8	6	HP:0000177
HumanPheno	Reduced impulse control	KDM3B CHD8 MAP1B STAG2 NEXMIF ASH1L	1.31e-03	1032	8	6	HP:5200045
HumanPheno	Restricted or repetitive behaviors or interests	CHD8 MAP1B NEXMIF ASH1L	1.48e-03	368	8	4	HP:0031432
HumanPheno	Perseverative thought	CHD8 MAP1B NEXMIF ASH1L	1.63e-03	377	8	4	HP:0030223
HumanPheno	Disordered formal thought process	CHD8 MAP1B NEXMIF ASH1L	1.78e-03	386	8	4	HP:0025769
HumanPheno	Hypothyroidism	CHD8 STAG2 NEXMIF ASH1L	1.99e-03	398	8	4	HP:0000821
HumanPheno	Duodenal atresia	KDM3B STAG2	2.07e-03	45	8	2	HP:0002247
HumanPheno	Sleep-wake cycle disturbance	CHD8 STAG2	2.07e-03	45	8	2	HP:0006979
HumanPheno	Abnormal thought pattern	CHD8 MAP1B NEXMIF ASH1L	2.11e-03	404	8	4	HP:5200269
HumanPheno	Abnormality of the chin	KDM3B CHD8 STAG2 NEXMIF	2.21e-03	409	8	4	HP:0000306
HumanPheno	Abnormality of the philtrum	CHD8 MAP1B STAG2 NEXMIF ASH1L	2.24e-03	726	8	5	HP:0000288
HumanPheno	Impairment in personality functioning	KDM3B CHD8 MAP1B STAG2 NEXMIF ASH1L	2.29e-03	1141	8	6	HP:0031466
HumanPheno	Overweight	CHD8 ASH1L	2.45e-03	49	8	2	HP:0025502
MousePheno	absent subplate	MAP1B TOP2B	1.55e-05	4	23	2	MP:0008443
MousePheno	abnormal subplate morphology	MAP1B TOP2B	9.26e-05	9	23	2	MP:0008440
Domain	-	ADD2 ADD3	1.12e-05	4	26	2	3.40.225.10
Domain	Aldolase_II/adducin_N	ADD2 ADD3	1.12e-05	4	26	2	IPR001303
Domain	Aldolase_II	ADD2 ADD3	1.12e-05	4	26	2	PF00596
Domain	Aldolase_II	ADD2 ADD3	1.12e-05	4	26	2	SM01007
Domain	AT_hook	PDS5B ASH1L	6.40e-04	27	26	2	SM00384
Domain	AT_hook_DNA-bd_motif	PDS5B ASH1L	6.40e-04	27	26	2	IPR017956
Domain	SET	PRDM2 ASH1L	1.48e-03	41	26	2	PF00856
Domain	SET	PRDM2 ASH1L	1.86e-03	46	26	2	SM00317
Domain	SET_dom	PRDM2 ASH1L	2.19e-03	50	26	2	IPR001214
Domain	SET	PRDM2 ASH1L	2.19e-03	50	26	2	PS50280
Domain	NA-bd_OB-fold	PDCD11 IFI16	5.92e-03	83	26	2	IPR012340
Pathway	KEGG_MEDICUS_REFERENCE_ESTABLISHMENT_OF_COHESION	PDS5B STAG2	4.00e-05	7	20	2	M47869
Pathway	REACTOME_COHESIN_LOADING_ONTO_CHROMATIN	PDS5B STAG2	8.55e-05	10	20	2	M27178
Pathway	REACTOME_COHESIN_LOADING_ONTO_CHROMATIN	PDS5B STAG2	8.55e-05	10	20	2	MM14892
Pathway	REACTOME_ESTABLISHMENT_OF_SISTER_CHROMATID_COHESION	PDS5B STAG2	1.04e-04	11	20	2	M27177
Pathway	REACTOME_ESTABLISHMENT_OF_SISTER_CHROMATID_COHESION	PDS5B STAG2	1.04e-04	11	20	2	MM14891
Pathway	REACTOME_MITOTIC_TELOPHASE_CYTOKINESIS	PDS5B STAG2	1.48e-04	13	20	2	M27661
Pathway	REACTOME_MITOTIC_TELOPHASE_CYTOKINESIS	PDS5B STAG2	1.48e-04	13	20	2	MM15363
Pathway	REACTOME_IRF3_MEDIATED_INDUCTION_OF_TYPE_I_IFN	IFI16 DTX4	1.48e-04	13	20	2	M27240
Pathway	REACTOME_STING_MEDIATED_INDUCTION_OF_HOST_IMMUNE_RESPONSES	IFI16 DTX4	2.27e-04	16	20	2	M27045
Pathway	REACTOME_MISCELLANEOUS_TRANSPORT_AND_BINDING_EVENTS	ADD2 ADD3	5.63e-04	25	20	2	MM15172
Pathway	REACTOME_MISCELLANEOUS_TRANSPORT_AND_BINDING_EVENTS	ADD2 ADD3	6.09e-04	26	20	2	M27424
Pathway	WP_COHESIN_COMPLEX_CORNELIA_DE_LANGE_SYNDROME	PDS5B STAG2	1.04e-03	34	20	2	M42555
Pathway	REACTOME_S_PHASE	PDS5B RFC1 STAG2	1.09e-03	146	20	3	MM15378
Pathway	REACTOME_S_PHASE	PDS5B RFC1 STAG2	1.50e-03	163	20	3	M3158
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	KDM3B RBM6 PDS5B SCAF1 RFC1 RAPH1 IFI16 PRPF40A STAG2 TOP2B PRDM2	9.41e-12	774	28	11	15302935
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	RBM6 PDS5B PDCD11 CHD8 BBX RFC1 MAP1B PRPF40A STAG2 ELL TOP2B	8.76e-11	954	28	11	36373674
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	KDM3B RBM6 PDS5B PDCD11 PRPF40A STAG2 TOP2B	1.70e-09	272	28	7	31010829
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	PDS5B CHD8 MACROH2A2 BBX RFC1 PRPF40A TOP2B ASH1L	6.85e-09	533	28	8	30554943
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	KDM3B PDCD11 CHD8 MAP1B RAPH1 ZNF598 PRPF40A ADD3	8.63e-09	549	28	8	38280479
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	KDM3B PDS5B CHD8 BBX RFC1 STAG2 TOP2B PRDM2	1.90e-08	608	28	8	36089195
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	RBM6 PDS5B PDCD11 CHD8 RFC1 MAP1B PRPF40A STAG2	3.30e-08	653	28	8	22586326
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	PDCD11 SCAF1 BBX RFC1 IFI16 PRPF40A STAG2 TRAM1 TOP2B PRDM2	3.49e-08	1294	28	10	30804502
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	KDM3B CHD8 MAP1B IFI16 PRPF40A TOP2B ADD3	4.95e-08	444	28	7	34795231
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	KDM3B RFC1 MAP1B RAPH1 ZNF598 PRPF40A TOP2B ADD3	5.06e-07	934	28	8	33916271
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	KDM3B PDS5B PDCD11 SCAF1 CHD8 RFC1 PRPF40A TOP2B ADD2	5.65e-07	1318	28	9	30463901
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	PDS5B PDCD11 CHD8 RFC1 MAP1B STAG2	6.21e-07	394	28	6	27248496
Pubmed	Expression of adducin genes during erythropoiesis: a novel erythroid promoter for ADD2.	ADD2 ADD3	6.25e-07	2	28	2	15963851
Pubmed	Targeted deletion of the gamma-adducin gene (Add3) in mice reveals differences in alpha-adducin interactions in erythroid and nonerythroid cells.	ADD2 ADD3	6.25e-07	2	28	2	19425068
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	KDM3B PDS5B CHD8 RFC1 IFI16 PRPF40A STAG2 TOP2B	9.40e-07	1014	28	8	32416067
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	PDS5B PDCD11 SCAF1 MACROH2A2 MAP1B PRPF40A STAG2 TOP2B	1.01e-06	1024	28	8	24711643
Pubmed	Elf5-centered transcription factor hub controls trophoblast stem cell self-renewal and differentiation through stoichiometry-sensitive shifts in target gene networks.	RFC1 MAP1B PRPF40A TOP2B	1.35e-06	102	28	4	26584622
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	RBM6 PDS5B MACROH2A2 BBX MAP1B PRPF40A TOP2B ADD2	1.53e-06	1082	28	8	38697112
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	KDM3B PDS5B CHD8 RFC1 IFI16 STAG2 TOP2B PRDM2	1.76e-06	1103	28	8	34189442
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	RBM6 PDS5B PDCD11 MACROH2A2 RFC1 MAP1B TOP2B	1.82e-06	759	28	7	35915203
Pubmed	Immunofluorescence localization of an adducin-like protein in the chromosomes of mouse oocytes.	ADD2 ADD3	1.87e-06	3	28	2	1864459
Pubmed	Arterial properties in relation to genetic variations in the adducin subunits in a white population.	ADD2 ADD3	1.87e-06	3	28	2	18787518
Pubmed	Epistatic interaction between alpha- and gamma-adducin influences peripheral and central pulse pressures in white Europeans.	ADD2 ADD3	1.87e-06	3	28	2	15834281
Pubmed	Role of the adducin family genes in human essential hypertension.	ADD2 ADD3	1.87e-06	3	28	2	15716695
Pubmed	Gly460Trp alpha-adducin mutation as a possible mechanism leading to endolymphatic hydrops in Ménière's syndrome.	ADD2 ADD3	1.87e-06	3	28	2	18667944
Pubmed	Targeted disruption of the beta adducin gene (Add2) causes red blood cell spherocytosis in mice.	ADD2 ADD3	1.87e-06	3	28	2	10485892
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	CHD8 BBX RFC1 IFI16 TOP2B	2.90e-06	283	28	5	30585729
Pubmed	KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.	KDM3B MAP1B IFI16 PRPF40A	3.56e-06	130	28	4	35545047
Pubmed	beta-adducin (Add2) KO mice show synaptic plasticity, motor coordination and behavioral deficits accompanied by changes in the expression and phosphorylation levels of the alpha- and gamma-adducin subunits.	ADD2 ADD3	3.75e-06	4	28	2	19900187
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	PDCD11 RFC1 IFI16 PRPF40A TRAM1 ELL TOP2B	3.75e-06	847	28	7	35850772
Pubmed	ZBTB2 protein is a new partner of the Nucleosome Remodeling and Deacetylase (NuRD) complex.	PDCD11 SCAF1 MACROH2A2 PRPF40A TOP2B	6.13e-06	330	28	5	33301849
Pubmed	Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.	PDCD11 MACROH2A2 IFI16 PRPF40A TOP2B	6.31e-06	332	28	5	25693804
Pubmed	PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.	BBX RFC1 ZNF598 PRPF40A TOP2B	7.08e-06	340	28	5	24332808
Pubmed	Analysis of Ku70 S155 Phospho-Specific BioID2 Interactome Identifies Ku Association with TRIP12 in Response to DNA Damage.	CHD8 MACROH2A2 RFC1 MAP1B	7.33e-06	156	28	4	37108203
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	PDS5B PDCD11 CHD8 MACROH2A2 RFC1 MAP1B IFI16 TOP2B	7.96e-06	1353	28	8	29467282
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	PDS5B PDCD11 SCAF1 RFC1 PRPF40A STAG2 TOP2B PRDM2	1.16e-05	1425	28	8	30948266
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	PDS5B BBX MAP1B RAPH1 STAG2 EFCAB12 TOP2B ASH1L	1.27e-05	1442	28	8	35575683
Pubmed	Functional contribution of Pds5 to cohesin-mediated cohesion in human cells and Xenopus egg extracts.	PDS5B STAG2	1.31e-05	7	28	2	15855230
Pubmed	New nomenclature for chromatin-modifying enzymes.	KDM3B PRDM2 ASH1L	1.33e-05	57	28	3	18022353
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	RBM6 PDCD11 SCAF1 CHD8 BBX ZNF598 STAG2 TRAM1	1.66e-05	1497	28	8	31527615
Pubmed	Distinct roles of cohesin-SA1 and cohesin-SA2 in 3D chromosome organization.	PDS5B STAG2	1.74e-05	8	28	2	29867216
Pubmed	Quantitative analysis of cohesin complex stoichiometry and SMC3 modification-dependent protein interactions.	PDS5B STAG2	1.74e-05	8	28	2	21699228
Pubmed	Sororin is required for stable binding of cohesin to chromatin and for sister chromatid cohesion in interphase.	PDS5B STAG2	2.24e-05	9	28	2	17349791
Pubmed	Human Scc4 is required for cohesin binding to chromatin, sister-chromatid cohesion, and mitotic progression.	PDS5B STAG2	2.24e-05	9	28	2	16682347
Pubmed	Human Wapl is a cohesin-binding protein that promotes sister-chromatid resolution in mitotic prophase.	PDS5B STAG2	2.24e-05	9	28	2	17112726
Pubmed	Targeting SKA3 suppresses the proliferation and chemoresistance of laryngeal squamous cell carcinoma via impairing PLK1-AKT axis-mediated glycolysis.	RFC1 PRPF40A STAG2	2.69e-05	72	28	3	33106477
Pubmed	Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome.	CHD8 MACROH2A2 RFC1 MAP1B	2.78e-05	219	28	4	31353912
Pubmed	Scc1 sumoylation by Mms21 promotes sister chromatid recombination through counteracting Wapl.	PDS5B STAG2	2.80e-05	10	28	2	22751501
Pubmed	Phosphorylation-enabled binding of SGO1-PP2A to cohesin protects sororin and centromeric cohesion during mitosis.	PDS5B STAG2	2.80e-05	10	28	2	23242214
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	RBM6 PDS5B PDCD11 ELL	2.93e-05	222	28	4	37071664
Pubmed	The mouse adducin gene family: alternative splicing and chromosomal localization.	ADD2 ADD3	3.42e-05	11	28	2	10602987
Pubmed	Wapl controls the dynamic association of cohesin with chromatin.	PDS5B STAG2	3.42e-05	11	28	2	17113138
Pubmed	Phosphoproteomic analysis of the developing mouse brain.	PDS5B MAP1B PCDH1 ADD2	4.38e-05	246	28	4	15345747
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	SCAF1 CHD8 MACROH2A2 TOP2B	4.73e-05	251	28	4	31076518
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	MACROH2A2 BBX MAP1B ZNF598 STAG2 TOP2B	5.21e-05	857	28	6	25609649
Pubmed	Aurora B and Cdk1 mediate Wapl activation and release of acetylated cohesin from chromosomes by phosphorylating Sororin.	PDS5B STAG2	6.52e-05	15	28	2	23901111
Pubmed	Ku antigen, an origin-specific binding protein that associates with replication proteins, is required for mammalian DNA replication.	RFC1 TOP2B	6.52e-05	15	28	2	12393188
Pubmed	Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.	MACROH2A2 RAPH1 PCDH1 ADD2 ADD3	7.56e-05	558	28	5	35063084
Pubmed	The functional interactome landscape of the human histone deacetylase family.	PDCD11 BBX STAG2 ADD3	8.17e-05	289	28	4	23752268
Pubmed	Human transcription factor protein interaction networks.	RBM6 PDCD11 CHD8 BBX RFC1 PRPF40A PRDM2	1.08e-04	1429	28	7	35140242
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	PDCD11 RFC1 MAP1B IFI16 STAG2 TRAM1 TOP2B	1.13e-04	1440	28	7	30833792
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	RBM6 PDCD11 SCAF1 RFC1 PRPF40A TOP2B	1.15e-04	989	28	6	36424410
Pubmed	STING-Mediated IFI16 Degradation Negatively Controls Type I Interferon Production.	PDCD11 RFC1 MAP1B IFI16	1.15e-04	316	28	4	31665637
Pubmed	Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice.	ADD2 ADD3	1.18e-04	20	28	2	18723693
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	KDM3B PDCD11 CHD8 BBX	1.51e-04	339	28	4	30415952
Pubmed	NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.	RFC1 IFI16 TOP2B	1.53e-04	129	28	3	23022380
Pubmed	Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.	PDCD11 PRPF40A STAG2 TOP2B	1.53e-04	340	28	4	29478914
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	KDM3B PDS5B CHD8 TOP2B	1.54e-04	341	28	4	32971831
Pubmed	The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.	PDCD11 MACROH2A2 MAP1B IFI16	1.69e-04	349	28	4	25665578
Pubmed	The WW domain-containing proteins interact with the early spliceosome and participate in pre-mRNA splicing in vivo.	CHD8 PRPF40A	1.85e-04	25	28	2	15456888
Pubmed	SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice.	PDS5B RFC1 STAG2	2.38e-04	150	28	3	30154076
Pubmed	Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.	RBM6 MACROH2A2 MAP1B PRPF40A TOP2B	2.39e-04	714	28	5	28302793
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	KDM3B CHD8 ASH1L	2.72e-04	157	28	3	30186101
Pubmed	Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress.	PDCD11 IFI16 TOP2B	2.82e-04	159	28	3	22751105
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	CHD8 BBX MAP1B IFI16	3.11e-04	410	28	4	26949251
Pubmed	Proteomic analysis of SRm160-containing complexes reveals a conserved association with cohesin.	PRPF40A STAG2 TOP2B	3.44e-04	170	28	3	16159877
Pubmed	Gfi1b regulates the level of Wnt/β-catenin signaling in hematopoietic stem cells and megakaryocytes.	KDM3B CHD8	3.45e-04	34	28	2	30894540
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	KDM3B PDS5B BBX ZNF598 ASH1L	4.21e-04	808	28	5	20412781
Pubmed	Large-scale identification of mammalian proteins localized to nuclear sub-compartments.	RBM6 RFC1	4.32e-04	38	28	2	11555636
Pubmed	SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response.	PDCD11 PRPF40A STAG2 ELL	4.93e-04	463	28	4	34901782
Pubmed	Systematic identification and analysis of mammalian small ubiquitin-like modifier substrates.	TOP2B ADD3	5.03e-04	41	28	2	15561718
Pubmed	In vitro nuclear interactome of the HIV-1 Tat protein.	PDS5B CHD8 RFC1	5.13e-04	195	28	3	19454010
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	PDS5B CHD8 RFC1 TOP2B	5.17e-04	469	28	4	27634302
Pubmed	Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes.	KDM3B TOP2B	5.28e-04	42	28	2	35705031
Pubmed	Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies.	KDM3B RBM6	6.33e-04	46	28	2	21102462
Pubmed	Phosphoproteome analysis of the human mitotic spindle.	RFC1 TRAM1 TOP2B	6.36e-04	210	28	3	16565220
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	MACROH2A2 MAP1B RAPH1 STAG2	6.47e-04	498	28	4	36634849
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	RBM6 CHD8 RFC1 IFI16	6.72e-04	503	28	4	16964243
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	KDM3B RAPH1 PRPF40A ADD3	6.87e-04	506	28	4	30890647
Pubmed	A genome-wide short hairpin RNA screening of jurkat T-cells for human proteins contributing to productive HIV-1 replication.	PDS5B PRDM2 ADD2	7.09e-04	218	28	3	19460752
Pubmed	Characterizing WW domain interactions of tumor suppressor WWOX reveals its association with multiprotein networks.	KDM3B ZNF598 PRPF40A	7.28e-04	220	28	3	24550385
Pubmed	TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.	KDM3B PRPF40A TOP2B	7.28e-04	220	28	3	35785414
Pubmed	GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.	PDCD11 RFC1 TOP2B	7.37e-04	221	28	3	29991511
Interaction	NUP43 interactions	PDS5B PDCD11 SCAF1 CHD8 BBX RFC1 IFI16 TOP2B PRDM2 ASH1L	6.07e-09	625	28	10	int:NUP43
Interaction	PDS5A interactions	KDM3B RBM6 PDS5B PDCD11 RFC1 STAG2 TOP2B	3.43e-08	245	28	7	int:PDS5A
Interaction	SMC5 interactions	RBM6 PDS5B PDCD11 CHD8 BBX RFC1 MAP1B PRPF40A STAG2 ELL TOP2B	4.19e-08	1000	28	11	int:SMC5
Interaction	DDX23 interactions	RBM6 PDS5B PDCD11 SCAF1 MAP1B IFI16 PRPF40A TOP2B	2.00e-07	480	28	8	int:DDX23
Interaction	POLR1G interactions	PDS5B PDCD11 CHD8 BBX RFC1 STAG2 TOP2B PRDM2	2.30e-07	489	28	8	int:POLR1G
Interaction	BRD3 interactions	PDS5B SCAF1 CHD8 MACROH2A2 BBX RFC1 PRPF40A TOP2B	2.49e-07	494	28	8	int:BRD3
Interaction	H3C3 interactions	KDM3B PDS5B CHD8 BBX RFC1 STAG2 TOP2B PRDM2	2.53e-07	495	28	8	int:H3C3
Interaction	H3-3A interactions	KDM3B PDS5B CHD8 BBX RFC1 STAG2 TOP2B PRDM2 ASH1L	4.72e-07	749	28	9	int:H3-3A
Interaction	CENPA interactions	PDS5B PDCD11 BBX RFC1 STAG2 TOP2B PRDM2	6.40e-07	377	28	7	int:CENPA
Interaction	PARP1 interactions	PDS5B PDCD11 SCAF1 MACROH2A2 BBX RFC1 IFI16 PRPF40A STAG2 TOP2B PRDM2	6.74e-07	1316	28	11	int:PARP1
Interaction	WWTR1 interactions	PDCD11 CHD8 MAP1B RAPH1 ZNF598 PRPF40A ADD3	1.36e-06	422	28	7	int:WWTR1
Interaction	H1-4 interactions	PDCD11 SCAF1 BBX RFC1 IFI16 PRPF40A EFCAB12 TOP2B	2.11e-06	656	28	8	int:H1-4
Interaction	H3C1 interactions	PDS5B CHD8 MACROH2A2 BBX RFC1 STAG2 TOP2B PRDM2 ASH1L	2.20e-06	901	28	9	int:H3C1
Interaction	H2BC21 interactions	PDS5B CHD8 MACROH2A2 RFC1 MAP1B IFI16 TOP2B PRDM2	3.27e-06	696	28	8	int:H2BC21
Interaction	H2BC12 interactions	PDS5B SCAF1 MACROH2A2 MAP1B STAG2 TOP2B	4.45e-06	322	28	6	int:H2BC12
Interaction	SIRT7 interactions	RBM6 PDS5B PDCD11 CHD8 RFC1 MAP1B PRPF40A STAG2	5.36e-06	744	28	8	int:SIRT7
Interaction	MEN1 interactions	KDM3B PDS5B PDCD11 CHD8 RFC1 IFI16 PRPF40A TRAM1 TOP2B	6.52e-06	1029	28	9	int:MEN1
Interaction	POLR1E interactions	PDCD11 CHD8 BBX IFI16 ELL TOP2B	7.17e-06	350	28	6	int:POLR1E
Interaction	COIL interactions	PDS5B PDCD11 CHD8 BBX IFI16 STAG2 TOP2B	7.99e-06	552	28	7	int:COIL
Interaction	MACROH2A2 interactions	PDCD11 MACROH2A2 BBX RFC1 IFI16	9.69e-06	211	28	5	int:MACROH2A2
Interaction	H2BC8 interactions	PDS5B CHD8 MACROH2A2 BBX RFC1 STAG2 TOP2B	1.05e-05	576	28	7	int:H2BC8
Interaction	NUCKS1 interactions	KDM3B MACROH2A2 RFC1 PRPF40A TOP2B	1.19e-05	220	28	5	int:NUCKS1
Interaction	CIT interactions	PDS5B PDCD11 SCAF1 CHD8 MACROH2A2 IFI16 PRPF40A STAG2 TOP2B ASH1L	1.42e-05	1450	28	10	int:CIT
Interaction	SMC1A interactions	PDS5B PDCD11 MACROH2A2 RFC1 ZNF598 STAG2	1.97e-05	418	28	6	int:SMC1A
Interaction	OBSL1 interactions	PDS5B PDCD11 SCAF1 MACROH2A2 RFC1 PRPF40A STAG2 TOP2B	2.18e-05	902	28	8	int:OBSL1
Interaction	CBX3 interactions	PDS5B CHD8 BBX RFC1 IFI16 STAG2 TOP2B	2.21e-05	646	28	7	int:CBX3
Interaction	NIFK interactions	PDCD11 SCAF1 BBX RFC1 IFI16 TOP2B	2.34e-05	431	28	6	int:NIFK
Interaction	FGFBP1 interactions	PDCD11 SCAF1 BBX RFC1 ASH1L	2.51e-05	257	28	5	int:FGFBP1
Interaction	H2BC4 interactions	SCAF1 MACROH2A2 MAP1B STAG2 TOP2B	2.60e-05	259	28	5	int:H2BC4
Interaction	RRP8 interactions	PDCD11 SCAF1 MACROH2A2 RFC1 IFI16	2.60e-05	259	28	5	int:RRP8
Interaction	XRCC6 interactions	CHD8 MACROH2A2 BBX RFC1 MAP1B IFI16 PRPF40A TOP2B	2.68e-05	928	28	8	int:XRCC6
Interaction	PML interactions	KDM3B CHD8 MACROH2A2 MAP1B IFI16 PRPF40A TOP2B ADD3	2.78e-05	933	28	8	int:PML
Interaction	ZNF330 interactions	PDS5B PDCD11 BBX RFC1 STAG2 TOP2B	2.83e-05	446	28	6	int:ZNF330
Interaction	CEBPA interactions	KDM3B PDS5B PDCD11 CHD8 RFC1 IFI16 STAG2 TOP2B PRDM2	3.01e-05	1245	28	9	int:CEBPA
Interaction	APEX1 interactions	PDS5B PDCD11 BBX RFC1 RAPH1 ZNF598 STAG2 TOP2B PRDM2	3.55e-05	1271	28	9	int:APEX1
Interaction	TOP1 interactions	RBM6 SCAF1 MACROH2A2 RFC1 IFI16 PRPF40A TOP2B	3.57e-05	696	28	7	int:TOP1
Interaction	MAU2 interactions	PDCD11 PRPF40A STAG2 TOP2B	3.58e-05	136	28	4	int:MAU2
Interaction	ENO1 interactions	MACROH2A2 MAP1B ZNF598 IFI16 STAG2 NEXMIF PRDM2	3.74e-05	701	28	7	int:ENO1
Interaction	NAA40 interactions	KDM3B RFC1 MAP1B RAPH1 ZNF598 PRPF40A TOP2B ADD3	3.90e-05	978	28	8	int:NAA40
Interaction	MECP2 interactions	RBM6 PDS5B PDCD11 MACROH2A2 BBX MAP1B PRPF40A TOP2B ADD2	3.91e-05	1287	28	9	int:MECP2
Interaction	HECTD1 interactions	RBM6 PDS5B PDCD11 MACROH2A2 RFC1 MAP1B PRPF40A TOP2B	4.07e-05	984	28	8	int:HECTD1
Interaction	IFI16 interactions	PDCD11 MACROH2A2 RFC1 MAP1B IFI16 PRPF40A TOP2B	4.20e-05	714	28	7	int:IFI16
Interaction	H2BC15 interactions	PDS5B MACROH2A2 MAP1B ZNF598	4.48e-05	144	28	4	int:H2BC15
Interaction	ADARB1 interactions	PDCD11 SCAF1 CHD8 BBX RFC1 TOP2B	4.73e-05	489	28	6	int:ADARB1
Interaction	ELF5 interactions	RFC1 MAP1B PRPF40A TOP2B	4.85e-05	147	28	4	int:ELF5
Interaction	TUBA1B interactions	PDS5B MAP1B ZNF598 IFI16 PRPF40A STAG2	5.24e-05	498	28	6	int:TUBA1B
Interaction	SENP3 interactions	PDCD11 BBX RFC1 IFI16 TOP2B	5.33e-05	301	28	5	int:SENP3
Interaction	KIF23 interactions	PDCD11 MACROH2A2 RFC1 IFI16 PRPF40A STAG2 TOP2B ADD2	5.67e-05	1031	28	8	int:KIF23
Interaction	NR2C2 interactions	KDM3B PDS5B PDCD11 SCAF1 CHD8 RFC1 PRPF40A TOP2B ADD2	7.69e-05	1403	28	9	int:NR2C2
Interaction	CRISP3 interactions	ADD2 ADD3	8.32e-05	10	28	2	int:CRISP3
Interaction	DOT1L interactions	PDCD11 RFC1 IFI16 PRPF40A TRAM1 ELL TOP2B	9.11e-05	807	28	7	int:DOT1L
Interaction	TERF2IP interactions	KDM3B PDS5B CHD8 BBX RFC1 PRPF40A	9.26e-05	552	28	6	int:TERF2IP
Interaction	STK38 interactions	PDS5B MAP1B ZNF598 IFI16	1.11e-04	182	28	4	int:STK38
Interaction	SLX4 interactions	KDM3B RBM6 PDS5B PDCD11 CHD8 ELL	1.13e-04	572	28	6	int:SLX4
Interaction	AKR7L interactions	RBM6 PDCD11 RFC1	1.34e-04	72	28	3	int:AKR7L
Interaction	WFDC5 interactions	PDS5B STAG2	1.44e-04	13	28	2	int:WFDC5
Interaction	PRG4 interactions	MAP1B PRPF40A	1.68e-04	14	28	2	int:PRG4
Interaction	GNL2 interactions	BBX RFC1 IFI16 ADD2 ADD3	1.72e-04	386	28	5	int:GNL2
Interaction	H2BC13 interactions	PDS5B SCAF1 MAP1B IFI16	1.93e-04	210	28	4	int:H2BC13
Interaction	SNRNP40 interactions	RBM6 PDCD11 SCAF1 RFC1 PRPF40A TOP2B	2.03e-04	637	28	6	int:SNRNP40
Interaction	KLHL20 interactions	PDS5B MACROH2A2 STAG2 TOP2B	2.15e-04	216	28	4	int:KLHL20
Interaction	H2BC3 interactions	PDS5B CHD8 RFC1 MAP1B STAG2	2.17e-04	406	28	5	int:H2BC3
Interaction	SMC3 interactions	PDS5B PDCD11 ZNF598 STAG2 TOP2B	2.22e-04	408	28	5	int:SMC3
Interaction	CHD4 interactions	PDCD11 MACROH2A2 RFC1 ZNF598 IFI16 PRPF40A TOP2B	2.32e-04	938	28	7	int:CHD4
Interaction	NOP2 interactions	PDCD11 MACROH2A2 BBX IFI16 ASH1L	2.43e-04	416	28	5	int:NOP2
Interaction	RPLP0 interactions	PDCD11 SCAF1 MACROH2A2 BBX IFI16 PRPF40A	2.45e-04	660	28	6	int:RPLP0
Interaction	NLE1 interactions	PDCD11 MACROH2A2 IFI16 TOP2B	2.64e-04	228	28	4	int:NLE1
Interaction	ZSCAN31 interactions	PDCD11 BBX	2.81e-04	18	28	2	int:ZSCAN31
Interaction	RPL31 interactions	PDS5B PDCD11 SCAF1 BBX RFC1 TOP2B	2.88e-04	680	28	6	int:RPL31
Interaction	SSRP1 interactions	SCAF1 MACROH2A2 RFC1 IFI16 PRPF40A TOP2B	3.00e-04	685	28	6	int:SSRP1
Interaction	GAPDH interactions	KDM3B RFC1 MAP1B ZNF598 PRPF40A TOP2B	3.02e-04	686	28	6	int:GAPDH
Interaction	SNRNP70 interactions	SCAF1 BBX RFC1 MAP1B IFI16 PRPF40A TOP2B	3.11e-04	984	28	7	int:SNRNP70
Interaction	GLYR1 interactions	MACROH2A2 RFC1 IFI16 TOP2B	3.16e-04	239	28	4	int:GLYR1
Interaction	ANKRD29 interactions	ADD2 ADD3	3.48e-04	20	28	2	int:ANKRD29
Interaction	ZBTB2 interactions	PDCD11 SCAF1 MACROH2A2 PRPF40A TOP2B	3.49e-04	450	28	5	int:ZBTB2
Interaction	DHX40 interactions	RBM6 PDCD11 SCAF1 PRDM2	3.69e-04	249	28	4	int:DHX40
Interaction	SRPK2 interactions	PDCD11 SCAF1 MACROH2A2 PRPF40A EFCAB12 TOP2B	3.83e-04	717	28	6	int:SRPK2
Interaction	DDX21 interactions	PDCD11 MACROH2A2 MAP1B IFI16 PRPF40A STAG2	3.86e-04	718	28	6	int:DDX21
Interaction	PIPSL interactions	MACROH2A2 STAG2 TOP2B ASH1L	3.86e-04	252	28	4	int:PIPSL
Interaction	FEM1A interactions	RBM6 ADD2 ADD3	4.10e-04	105	28	3	int:FEM1A
Interaction	H1-0 interactions	CHD8 MACROH2A2 MAP1B IFI16	4.10e-04	256	28	4	int:H1-0
Interaction	MYCN interactions	RBM6 PDS5B PDCD11 SCAF1 MACROH2A2 BBX MAP1B PRPF40A	4.13e-04	1373	28	8	int:MYCN
Interaction	HNRNPU interactions	PDCD11 RFC1 IFI16 PRPF40A STAG2 ELL PRDM2	4.22e-04	1035	28	7	int:HNRNPU
Interaction	H2AB2 interactions	PDCD11 SCAF1 BBX	4.33e-04	107	28	3	int:H2AB2
Interaction	RBM39 interactions	RBM6 MACROH2A2 MAP1B IFI16 PRPF40A STAG2 TOP2B	4.40e-04	1042	28	7	int:RBM39
Interaction	ACTB interactions	MAP1B RAPH1 IFI16 STAG2 TOP2B ADD2 ADD3	5.55e-04	1083	28	7	int:ACTB
Interaction	SCARNA22 interactions	PDCD11 IFI16 TOP2B	5.76e-04	118	28	3	int:SCARNA22
Interaction	ELL3 interactions	ELL ADD3	5.93e-04	26	28	2	int:ELL3
Interaction	RBBP7 interactions	MAP1B ZNF598 PRPF40A STAG2 ASH1L	6.01e-04	507	28	5	int:RBBP7
Interaction	EPRS1 interactions	PDCD11 MAP1B RAPH1 ZNF598 DTX4	6.34e-04	513	28	5	int:EPRS1
Interaction	HDAC1 interactions	CHD8 BBX RFC1 RAPH1 STAG2 ELL TOP2B	6.36e-04	1108	28	7	int:HDAC1
Interaction	CBX1 interactions	KDM3B IFI16 NEXMIF TOP2B	6.38e-04	288	28	4	int:CBX1
Interaction	PSPC1 interactions	RFC1 ZNF598 IFI16 PRPF40A TOP2B	6.46e-04	515	28	5	int:PSPC1
Interaction	DHX8 interactions	RBM6 SCAF1 IFI16 PRPF40A	6.72e-04	292	28	4	int:DHX8
Interaction	TOP2A interactions	PDS5B MACROH2A2 RFC1 IFI16 TOP2B	6.75e-04	520	28	5	int:TOP2A
Interaction	MFAP1 interactions	RBM6 PRPF40A ELL TOP2B	6.98e-04	295	28	4	int:MFAP1
Interaction	CEP164 interactions	PDS5B PDCD11 TOP2B	7.30e-04	128	28	3	int:CEP164
Interaction	RPL15 interactions	PDCD11 MACROH2A2 BBX IFI16 ASH1L	7.35e-04	530	28	5	int:RPL15
Interaction	PNN interactions	RBM6 SCAF1 IFI16 PRPF40A	7.62e-04	302	28	4	int:PNN
Interaction	RPL8 interactions	PDCD11 SCAF1 MACROH2A2 ZNF598 IFI16	7.93e-04	539	28	5	int:RPL8
Cytoband	1q22	IFI16 ASH1L	5.61e-04	57	28	2	1q22
Cytoband	Ensembl 112 genes in cytogenetic band chr5q31	KDM3B PCDH1 MEIKIN	7.86e-04	298	28	3	chr5q31
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	PRDM2 ASH1L	6.38e-04	34	20	2	487
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	MAP1B ELL	1.68e-02	181	20	2	694
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	PDS5B BBX IFI16 PRPF40A STAG2 TRAM1 ELL TOP2B PRDM2 ASH1L	1.77e-06	1492	28	10	M40023
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	PDS5B BBX RFC1 IFI16 STAG2 TOP2B ADD3	4.46e-06	656	28	7	M18979
Coexpression	PUJANA_ATM_PCC_NETWORK	KDM3B RBM6 PDS5B RFC1 IFI16 PRPF40A STAG2 TOP2B PRDM2	9.13e-06	1394	28	9	M9585
Coexpression	SMID_BREAST_CANCER_LUMINAL_B_DN	CCL21 MAP1B IFI16 DTX4 ADD2 ADD3	3.04e-05	587	28	6	M17572
Coexpression	GSE21360_PRIMARY_VS_QUATERNARY_MEMORY_CD8_TCELL_DN	BBX STAG2 TOP2B ADD3	5.61e-05	198	28	4	M7610
Coexpression	SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX1_UP	KDM3B PRPF40A	9.93e-05	14	28	2	M1353
Coexpression	SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX1_UP	KDM3B PRPF40A	9.93e-05	14	28	2	MM565
Coexpression	STEINER_ERYTHROCYTE_MEMBRANE_GENES	ADD2 ADD3	9.93e-05	14	28	2	M2442
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_top-relative-expression-ranked_1000	PDS5B RFC1 MAP1B IFI16 PRPF40A TOP2B ADD3 ASH1L	6.89e-06	811	28	8	gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#5_top-relative-expression-ranked_1000	PDS5B RFC1 MAP1B TOP2B ADD3 ASH1L	1.09e-05	397	28	6	gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000_k5
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_k-means-cluster#4_top-relative-expression-ranked_500	MAP1B TOP2B ADD3	6.04e-05	58	28	3	gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_500_k4
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_k-means-cluster#4_top-relative-expression-ranked_200	MAP1B IFI16	7.50e-05	10	28	2	gudmap_developingLowerUrinaryTract_P1_bladder_J_200_k4
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#4	PDS5B MAP1B RAPH1 STAG2 DTX4 PRDM2	1.05e-04	595	28	6	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K4
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_top-relative-expression-ranked_500	MACROH2A2 MAP1B IFI16 TOP2B ADD3	2.00e-04	420	28	5	gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_top-relative-expression-ranked_500	PDS5B MAP1B IFI16 PRPF40A TOP2B	2.04e-04	422	28	5	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k-means-cluster#4_top-relative-expression-ranked_500	PDS5B MAP1B TOP2B	2.38e-04	92	28	3	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k4_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_k-means-cluster#1_top-relative-expression-ranked_1000	MAP1B TOP2B ADD3	3.14e-04	101	28	3	gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_1000_k1
CoexpressionAtlas	FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_1000_k-means-cluster#1	RBM6 MAP1B PRPF40A DTX4	3.52e-04	259	28	4	Facebase_RNAseq_e8.5_Floor Plate_1000_K1
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#2_top-relative-expression-ranked_200	CHD8 ASH1L	4.17e-04	23	28	2	gudmap_developingGonad_e18.5_epididymis_200_k2
CoexpressionAtlas	DevelopingGonad_P2_ovary_emap-30224_top-relative-expression-ranked_1000	CHD8 BBX RFC1 NEXMIF ADD3 ASH1L	4.24e-04	770	28	6	gudmap_developingGonad_P2_ovary_1000
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_1000	CHD8 BBX RFC1 NEXMIF ADD3 ASH1L	4.48e-04	778	28	6	gudmap_developingGonad_e18.5_ovary_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_k-means-cluster#5_top-relative-expression-ranked_500	MAP1B IFI16	4.55e-04	24	28	2	gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_500_k5
CoexpressionAtlas	DevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_1000	RBM6 CHD8 BBX RFC1 NEXMIF ASH1L	5.40e-04	806	28	6	gudmap_developingGonad_e12.5_epididymis_1000
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3	RBM6 BBX MAP1B PRPF40A DTX4	5.91e-04	532	28	5	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlas	DevelopingGonad_e14.5_ testes_emap-6710_top-relative-expression-ranked_1000	RBM6 CHD8 BBX RFC1 PRPF40A NEXMIF	5.99e-04	822	28	6	gudmap_developingGonad_e14.5_ testes_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_k-means-cluster#5_top-relative-expression-ranked_500	MAP1B IFI16	7.61e-04	31	28	2	gudmap_developingLowerUrinaryTract_P1_bladder_J_500_k5
CoexpressionAtlas	DevelopingGonad_P2_ovary_emap-30224_k-means-cluster#1_top-relative-expression-ranked_1000	BBX RFC1 ADD3	8.31e-04	141	28	3	gudmap_developingGonad_P2_ovary_1000_k1
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#2_top-relative-expression-ranked_1000	PDS5B MAP1B TOP2B ASH1L	8.73e-04	330	28	4	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k2_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_ureter_emap-30363_k-means-cluster#4_top-relative-expression-ranked_1000	MAP1B IFI16 TOP2B	1.01e-03	151	28	3	gudmap_developingLowerUrinaryTract_P1_ureter_1000_k4
CoexpressionAtlas	DevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_200	CHD8 NEXMIF ASH1L	1.09e-03	155	28	3	gudmap_developingGonad_e16.5_ovary_200
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRPF40A STAG2 TOP2B ASH1L	5.95e-06	191	28	4	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRPF40A STAG2 TOP2B ASH1L	5.95e-06	191	28	4	09db184cb90fe282a14474d7217068c58092c6f8
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRPF40A STAG2 TOP2B ASH1L	5.95e-06	191	28	4	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	ASK452-Endothelial-Lymphatic\|Endothelial / Donor, Lineage and Cell class of Lung cells from Dropseq	CCL21 MAP1B RAPH1 ADD3	6.46e-06	195	28	4	20f492299a684ac1b7dd1bbc36a533cd6f9a1c93
ToppCell	10x5'v1-week_14-16-Lymphocytic_B\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	BBX IFI16 TRAM1 TOP2B	6.72e-06	197	28	4	31dfd9842410b5c629f39b5130233995dceb0aef
ToppCell	10x5'v1-week_14-16-Lymphocytic_B-B_lineage\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	BBX IFI16 TRAM1 TOP2B	6.72e-06	197	28	4	7290f05d0b8465637420119941bcbf2fae44a7e4
ToppCell	10x3'2.3-week_17-19-Lymphocytic_B\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	BBX TRAM1 TOP2B PRDM2	6.86e-06	198	28	4	5f465cf5c7493e32d9afe9e9d05757d0a95acc33
ToppCell	10x3'2.3-week_17-19-Lymphocytic_B-B_lineage\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	BBX TRAM1 TOP2B PRDM2	6.86e-06	198	28	4	77ce3fe1ab161c0faf8987e73a64ab61294b9255
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	BBX RFC1 MAP1B STAG2	7.00e-06	199	28	4	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	metastatic_Lymph_Node-Endothelial_cells-Lymphatic_ECs\|Endothelial_cells / Location, Cell class and cell subclass	CCL21 ADD3	1.30e-04	27	28	2	84a4a582ec4fcf9d3ab92b553814eada10d0e452
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CCL21 MAP1B RAPH1	1.68e-04	172	28	3	1ef243bce63d841c25e4b74d029d1377f84bcc3d
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CCL21 MAP1B RAPH1	1.68e-04	172	28	3	ab1c81be29f93ca8920c6ab5ab92f497a9256d3f
ToppCell	ASK452-Endothelial-Lymphatic\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	CCL21 RAPH1 ADD2	1.79e-04	176	28	3	b4d280ecc07701d526f50d44c45ea91b3eeb00b1
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	CHD8 IFI16 ASH1L	2.01e-04	183	28	3	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_mature-Lymphatic_EC_mature_L.2.5.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCL21 MAP1B ADD2	2.04e-04	184	28	3	e5756afa3181186f9b65552b8df5359ef4024bee
ToppCell	droplet-Tongue-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP1B PRPF40A ASH1L	2.18e-04	188	28	3	d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCell	367C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CCL21 MAP1B ADD3	2.32e-04	192	28	3	5f4f44f15d3a2846981e68296643a4634930a211
ToppCell	367C-Endothelial_cells-Endothelial-F_(Lymphatics)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CCL21 MAP1B ADD3	2.32e-04	192	28	3	5e709c0714e8eba27e03a6def0544256bedb3ced
ToppCell	(6)_Endothelial_cells-(6)_Endothelial-F_(Lymphatics)\|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	CCL21 MAP1B ADD3	2.39e-04	194	28	3	9441202d6fa2ffbef9277d48ae9bc98876c26ec5
ToppCell	COPD-Endothelial-Lymphatic\|Endothelial / Disease state, Lineage and Cell class	CCL21 MAP1B ADD3	2.42e-04	195	28	3	e91ce548ae7224661ee5d2f2639794a5f69798ee
ToppCell	10x5'v1-week_14-16-Lymphocytic_B-B_lineage-pro_B_progenitor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	BBX IFI16 TOP2B	2.42e-04	195	28	3	dc84a910b6f6eb9994cd683aa4fd813a82198e5f
ToppCell	(1)_T_cells-(1)_T_CD4_naive\|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	RBM6 ADD2 ASH1L	2.42e-04	195	28	3	d3fa551bc6f5ee5890af1040415e61ecd5d46201
ToppCell	IPF-Endothelial-Lymphatic\|Endothelial / Disease state, Lineage and Cell class	CCL21 MAP1B ADD3	2.42e-04	195	28	3	de88e9d22044b4b3e29676ad02b3e9299cc920ad
ToppCell	343B-Endothelial_cells-Endothelial-F_(Lymphatics)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CCL21 MAP1B ADD3	2.42e-04	195	28	3	fc75f04eb475c8139cc5c35e6be22e73fb2be9e6
ToppCell	343B-Endothelial_cells-Endothelial-F_(Lymphatics)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CCL21 MAP1B ADD3	2.42e-04	195	28	3	83d45ff5e5bc704448431149fffb2e4c1278f279
ToppCell	Control-Endothelial-Lymphatic\|Endothelial / Disease state, Lineage and Cell class	CCL21 MAP1B ADD3	2.46e-04	196	28	3	e0cf617b0f5d9c3c19574f587a3d0ccbf93d8ca4
ToppCell	facs-Bladder-nan-3m\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRAM1 TOP2B ADD3	2.46e-04	196	28	3	44f5b1b474399c9316729155f2ea95a82ca66e30
ToppCell	356C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CCL21 MAP1B ADD3	2.46e-04	196	28	3	b04ca69b0ed44e09c989b575f747e1e819cd8008
ToppCell	356C-Endothelial_cells-Endothelial-F_(Lymphatics)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CCL21 MAP1B ADD3	2.46e-04	196	28	3	a31e227de2dc077b81881295b012d22fedbd65ed
ToppCell	facs-Bladder-nan-3m-Epithelial\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRAM1 TOP2B ADD3	2.46e-04	196	28	3	c0e90d964baa2eb4fbd18a52379ccec5d3bf59a8
ToppCell	Endothelial_cells-Endothelial-B\|Endothelial_cells / lung cells shred on cell class, cell subclass, sample id	CCL21 MAP1B ADD3	2.46e-04	196	28	3	36f95f9ef74eb951e41ef46fd136ceaef45208fc
ToppCell	390C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CCL21 MAP1B ADD3	2.50e-04	197	28	3	c84e988c2ad06087aafda9e3b68e9e72fd0e75f1
ToppCell	normal_Lung-Endothelial_cells-Lymphatic_ECs\|Endothelial_cells / Location, Cell class and cell subclass	CCL21 MAP1B ADD3	2.50e-04	197	28	3	c838d0f64e3b43a616a9e381b8139bfe9aa32da7
ToppCell	390C-Endothelial_cells-Endothelial-F_(Lymphatics)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CCL21 MAP1B ADD3	2.50e-04	197	28	3	6195f945b3fd6da07907619267d49e96d1044f8f
ToppCell	tumor_Lung-Endothelial_cells-Lymphatic_ECs\|Endothelial_cells / Location, Cell class and cell subclass	CCL21 MAP1B ADD3	2.50e-04	197	28	3	a05237ee6d31d9eab491dd7007859d6285cf1424
ToppCell	distal-Endothelial-Lymphatic-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CCL21 MAP1B ADD3	2.50e-04	197	28	3	8f2e19409ebe9a490d5a245fa82c765ed6d77c3e
ToppCell	Transplant_Alveoli_and_parenchyma-Endothelial-Lymphatic\|Endothelial / Tissue, Lineage and Cell class of Lung Cells from 10X	CCL21 MAP1B ADD3	2.54e-04	198	28	3	7a99c341736a4a2ac48ef8e2f7951f21a7378946
ToppCell	systemic_lupus_erythematosus-flare\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	IFI16 ADD3 ASH1L	2.54e-04	198	28	3	4c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCell	LAM-Endothelial-LymEndo\|Endothelial / Condition, Lineage and Cell class	CCL21 MAP1B ADD3	2.54e-04	198	28	3	ba64b1c95dfaa995045239d412e725596f6c482e
ToppCell	ILEUM-inflamed-(8)_Fibroblast-(8)_Pericytes\|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CCL21 MAP1B PCDH1	2.54e-04	198	28	3	5e274c5597d8720290d452465f0bd40637cb3f27
ToppCell	(05)_Secretory-(2)_GFP_FOXI1\|(05)_Secretory / shred by cell type by condition	PRPF40A STAG2 TRAM1	2.57e-04	199	28	3	d72d87e1e530ed894c0ad5e7b5b2b1d6b59fa098
ToppCell	NS-control-d_0-4-Epithelial-Secretory\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RAPH1 IFI16 DTX4	2.57e-04	199	28	3	32bdfff40fd442b88489c8b0f79af3927a51a03c
ToppCell	(10)_Ciliated-(2)_GFP_FOXI1\|(10)_Ciliated / shred by cell type by condition	PRPF40A STAG2 TRAM1	2.57e-04	199	28	3	61b1ed2db71b96157b92b7535d1955a4033098da
ToppCell	control-Epithelial-Secretory\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RAPH1 IFI16 DTX4	2.57e-04	199	28	3	262e5b8a52c8ddb0b47048c786e8bdb7158e1b9a
ToppCell	368C-Fibroblasts-Fibroblast-D-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	IFI16 TRAM1 ADD3	2.57e-04	199	28	3	8766796041965a1ba40ad7abdbc244bf1418c209
ToppCell	(09)_Interm._secr.>cil.-(2)_GFP_FOXI1\|(09)_Interm._secr.>cil. / shred by cell type by condition	PRPF40A STAG2 TRAM1	2.57e-04	199	28	3	fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell	Frontal_cortex-Neuronal\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	MAP1B NEXMIF ADD2	2.57e-04	199	28	3	f88039d862f3bfa01dc39d2de4f3f548dc5a0e61
ToppCell	356C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	CCL21 IFI16 ADD2	2.57e-04	199	28	3	f4fdf94c561dca35bb17766d908c5030655f43eb
ToppCell	Caecum-T_cell-Activated_CD4_T\|T_cell / Region, Cell class and subclass	ADD2 ADD3 ASH1L	2.57e-04	199	28	3	13173cc4dcc8e856680372b0a4ad4f36afa892c1
ToppCell	368C-Fibroblasts-Fibroblast-D\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	IFI16 TRAM1 ADD3	2.57e-04	199	28	3	d39b40d84c72bdde756b805063317ecfad3784f8
ToppCell	356C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	CCL21 IFI16 ADD2	2.57e-04	199	28	3	c0fe99ed906d0eb99cccdab9a1fa32c17b3542e7
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	IFI16 ADD3 ASH1L	2.61e-04	200	28	3	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Neuronal-Neuron\|3m / Sample Type, Dataset, Time_group, and Cell type.	MACROH2A2 BBX MAP1B	2.61e-04	200	28	3	3d134ae3c48ff4d1849db4fbe44ff73fb6c8c779
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	IFI16 PRDM2 ASH1L	2.61e-04	200	28	3	12f1685ce8f218433068e090c9d839cd5a1910bf
Computational	Genes upregulated in subsets of cells of a given type within various tumors	RBM6 PRDM2 ASH1L	8.71e-05	50	19	3	GAVISH_3CA_METAPROGRAM_B_CELLS_B_CELLS_1
Drug	9-chloroacridine	CCL21 TOP2B	2.18e-05	6	28	2	CID000071013
Drug	liriodenine	PDS5B TOP2B	5.22e-05	9	28	2	CID000010144
Drug	ICI 182,780; Down 200; 1uM; MCF7; HT_HG-U133A_EA	PDS5B PRPF40A STAG2 ADD3	6.25e-05	177	28	4	985_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	KDM3B PDS5B MACROH2A2 IFI16	6.53e-05	179	28	4	6609_DN
Drug	Captopril [62571-86-2]; Down 200; 17.2uM; PC3; HT_HG-U133A	BBX PRPF40A STAG2 ADD3	6.53e-05	179	28	4	4585_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	PDS5B MACROH2A2 IFI16 STAG2	6.67e-05	180	28	4	6886_DN
Drug	Neostigmine bromide [114-80-7]; Down 200; 13.2uM; PC3; HT_HG-U133A	BBX IFI16 PRPF40A PRDM2	7.89e-05	188	28	4	6735_DN
Drug	Acetohexamide [968-81-0]; Up 200; 12.4uM; PC3; HT_HG-U133A	IFI16 PCDH1 PRDM2 ADD3	8.56e-05	192	28	4	1829_UP
Drug	AG-013608 [351320-38-2]; Up 200; 10uM; MCF7; HT_HG-U133A	CCL21 IFI16 PCDH1 ADD2	8.74e-05	193	28	4	5904_UP
Drug	Fenbufen [36330-85-5]; Down 200; 15.8uM; MCF7; HT_HG-U133A	RBM6 MACROH2A2 ELL DTX4	9.09e-05	195	28	4	2308_DN
Drug	sulfosuccinimidobiotin	CCL21 MAP1B	9.55e-05	12	28	2	CID000083894
Drug	pioglitazone HCl; Up 200; 10uM; MCF7; HT_HG-U133A	MAP1B PCDH1 ELL PRDM2	9.65e-05	198	28	4	7083_UP
Disease	spastic quadriplegic cerebral palsy 3 (implicated_via_orthology)	ADD2 ADD3	2.60e-06	3	28	2	DOID:0081361 (implicated_via_orthology)
Disease	cerebral palsy (implicated_via_orthology)	ADD2 ADD3	3.89e-05	10	28	2	DOID:1969 (implicated_via_orthology)
Disease	Intellectual Disability	KDM3B CHD8 MAP1B STAG2 ASH1L	5.75e-05	447	28	5	C3714756
Disease	mean reticulocyte volume	RBM6 PDS5B RFC1 RAPH1 STAG2 NEXMIF	8.75e-05	799	28	6	EFO_0010701
Disease	Myeloid Leukemia	STAG2 TOP2B	1.32e-04	18	28	2	C0023470
Disease	Leukemia, Monocytic, Chronic	STAG2 TOP2B	1.32e-04	18	28	2	C0023466
Disease	periodontal measurement	IFI16 ASH1L	2.37e-04	24	28	2	EFO_0007780
Disease	autism spectrum disorder (implicated_via_orthology)	CHD8 NEXMIF ASH1L	3.99e-04	152	28	3	DOID:0060041 (implicated_via_orthology)
Disease	osteoarthritis	RBM6 RAPH1 PRDM2	1.20e-03	222	28	3	MONDO_0005178
Disease	serum albumin measurement	SCAF1 BBX RAPH1 ELL	2.24e-03	592	28	4	EFO_0004535
Disease	age at menarche	KDM3B RBM6 PRPF40A PRDM2	2.27e-03	594	28	4	EFO_0004703
Disease	Neurodevelopmental Disorders	NEXMIF ASH1L	3.52e-03	93	28	2	C1535926
Disease	puberty onset measurement	PRPF40A PRDM2	6.26e-03	125	28	2	EFO_0005677
Disease	hypertension (implicated_via_orthology)	ADD2 ADD3	6.56e-03	128	28	2	DOID:10763 (implicated_via_orthology)
Disease	Global developmental delay	KDM3B STAG2	7.06e-03	133	28	2	C0557874
Disease	Bladder Neoplasm	STAG2 PRDM2	7.79e-03	140	28	2	C0005695
Disease	Malignant neoplasm of urinary bladder	STAG2 PRDM2	7.90e-03	141	28	2	C0005684
Disease	fibrinogen measurement, coronary artery disease	RAPH1 ELL	9.36e-03	154	28	2	EFO_0001645, EFO_0004623

Protein segments in the cluster

Peptide	Gene	Start	Entry
KSSKTKPKKLGTGTT	ASH1L	231	Q9NR48
KTGKKGKGSKGCKRT	CCL21	111	O00585
PKKSKTSGASKTKGK	CHD8	516	Q9HCK8
GSPSRSKPKKKSKKH	ELL	441	P55199
GTSGSKKFKKTKPKE	BBX	666	Q8WY36
GSPSKSPSKKKKKFR	ADD3	676	Q9UEY8
GKKSKAAKPRTSKKS	MACROH2A2	146	Q9P0M6
SRKTTKKQAKKGKTP	DTX4	376	Q9Y2E6
GKSKRTDKKTPKKSK	EFCAB12	461	Q6NXP0
PGKKTSKTSSPGGKK	RAPH1	956	Q70E73
PTMKTSKKGSKKKSG	PDS5B	1306	Q9NTI5
EKTKTKKPGTKTKSS	MAP1B	2241	P46821
KKPGTKTKSSSPVKK	MAP1B	2246	P46821
SKGNKSKGKKSKSPK	PCDH1	906	Q08174
GGTLKAVKSSKGKKK	KDM3B	261	Q7LBC6
KKKKTNSSTPGKKNR	MEIKIN	256	A0A087WXM9
RSESKHKSPKKKTGK	PRPF40A	911	O75400
KSTKEKAGPKGSKVS	IFI16	131	Q16666
SKRSSPKSRKGKKKS	PRDM2	161	Q13029
KEKKPTSQGKSSSKK	RBM6	831	P78332
GRKTSKTTSKKPKKT	TOP2B	1561	Q02880
KLKGETKTPKKTKSS	RFC1	346	P35251
KVSKSRKKSSPSKSG	NEXMIF	1171	Q5QGS0
GSPSKSPSKKKKKFR	ADD2	696	P35612
STKRKKSQKGPAKTK	PDCD11	41	Q14690
RSKKSKPSTGKRKVV	STAG2	1071	Q8N3U4
AGAKKTKGTKGKTKP	SCAF1	906	Q9H7N4
TKGTKGKTKPSKTRK	SCAF1	911	Q9H7N4
GKTKPSKTRKKVRSG	SCAF1	916	Q9H7N4
KVGKKKKVGSEKPGT	ZNF598	586	Q86UK7
KKPTVTKGRSSKKGT	TRAM1	336	Q15629