Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19 ERVK-25

1.99e-07371396GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19 ERVK-25

2.35e-07381396GO:0070001
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH2 CCDC88B DNAH7 DNAH17

4.04e-05281394GO:0051959
GeneOntologyMolecularFunctionRNA-DNA hybrid ribonuclease activity

ERVK-6 NYNRIN ERVK-8

5.23e-05111393GO:0004523
GeneOntologyMolecularFunctiondihydrofolic acid binding

DHFR DHFR2

1.44e-0431392GO:0051871
GeneOntologyMolecularFunctiondihydrofolate reductase activity

DHFR DHFR2

1.44e-0431392GO:0004146
GeneOntologyMolecularFunctionphosphatidate cytidylyltransferase activity

CDS1 CDS2

1.44e-0431392GO:0004605
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH2 DNAH7 DNAH17

2.49e-04181393GO:0008569
GeneOntologyMolecularFunctionRNA nuclease activity

ERVK-6 XRN2 TSEN2 NYNRIN ERVK-8 HELZ2

3.82e-041361396GO:0004540
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

ERVK-6 XRN2 DHX57 VARS2 TSEN2 LIG3 CHTF18 NYNRIN RECQL5 ERVK-8 HELZ2 DDX24 TOP3A

5.79e-0464513913GO:0140640
GeneOntologyBiologicalProcesscell-cell fusion

ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19 ERVS71-1

2.37e-05851396GO:0140253
GeneOntologyBiologicalProcesssyncytium formation by plasma membrane fusion

ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19 ERVS71-1

2.37e-05851396GO:0000768
GeneOntologyBiologicalProcesssyncytium formation

ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19 ERVS71-1

3.09e-05891396GO:0006949
GeneOntologyBiologicalProcessDNA integration

ERVK-6 NYNRIN ERVK-8

8.15e-05131393GO:0015074
MousePhenoabnormal sternum morphology

PDS5B ASH1L PGBD1 FGFRL1 FHIP1B MTMR11 IGF2R TULP4 PAH CPLANE1

1.82e-0525510310MP:0000157
DomainCUT

CUX2 ONECUT1 ONECUT3 CUX1

8.72e-0871344PS51042
DomainCUT

CUX2 ONECUT1 ONECUT3 CUX1

8.72e-0871344PF02376
DomainCUT_dom

CUX2 ONECUT1 ONECUT3 CUX1

8.72e-0871344IPR003350
DomainCUT

CUX2 ONECUT1 ONECUT3 CUX1

8.72e-0871344SM01109
DomainLRRC37AB_C

LRRC37A3 LRRC37A2 LRRC37A

1.44e-0641343IPR029423
DomainLRRC37AB_C

LRRC37A3 LRRC37A2 LRRC37A

1.44e-0641343PF14914
DomainLRRC37_N

LRRC37A3 LRRC37A2 LRRC37A

1.44e-0641343IPR032754
DomainLRRC37

LRRC37A3 LRRC37A2 LRRC37A

1.44e-0641343PF15779
DomainLRRC37A/B-like

LRRC37A3 LRRC37A2 LRRC37A

1.44e-0641343IPR015753
Domain-

CUX2 ONECUT1 ONECUT3 CUX1

3.91e-052713441.10.260.40
DomainPC_trans

CDS1 CDS2

5.11e-0521342IPR000374
DomainDHFR_1

DHFR DHFR2

5.11e-0521342PF00186
DomainDHFR_1

DHFR DHFR2

5.11e-0521342PS00075
DomainPC_Trfase_euk

CDS1 CDS2

5.11e-0521342IPR016720
DomainDHFR_dom

DHFR DHFR2

5.11e-0521342IPR001796
DomainCDS

CDS1 CDS2

5.11e-0521342PS01315
DomainDHFR_2

DHFR DHFR2

5.11e-0521342PS51330
Domain-

DHFR DHFR2

5.11e-05213423.40.430.10
DomainDHFR-like_dom

DHFR DHFR2

5.11e-0521342IPR024072
DomainDHFR

DHFR DHFR2

5.11e-0521342IPR012259
DomainLambda_DNA-bd_dom

CUX2 ONECUT1 ONECUT3 CUX1

5.23e-05291344IPR010982
DomainTECPR

HERC2 TECPR1

1.53e-0431342SM00706
DomainBeta-propeller_rpt_TECPR

HERC2 TECPR1

1.53e-0431342IPR006624
Domain-

IBTK HERC2 TECPR1

5.03e-042213432.130.10.30
DomainINTEGRASE

ERVK-6 NYNRIN

5.04e-0451342PS50994
DomainIntegrase_cat-core

ERVK-6 NYNRIN

5.04e-0451342IPR001584
DomainRCC1/BLIP-II

IBTK HERC2 TECPR1

5.76e-04231343IPR009091
DomainAT_hook

PDS5B ASH1L FAM171B

9.31e-04271343SM00384
DomainAT_hook_DNA-bd_motif

PDS5B ASH1L FAM171B

9.31e-04271343IPR017956
DomainAPC_su10/DOC_dom

ZZEF1 HERC2

1.05e-0371342IPR004939
DomainDOC

ZZEF1 HERC2

1.05e-0371342PS51284
DomainANAPC10

ZZEF1 HERC2

1.05e-0371342PF03256
DomainAPC10

ZZEF1 HERC2

1.05e-0371342SM01337
Pubmed

Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.

ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19 ERVS71-1

4.28e-1212145614557543
Pubmed

Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins.

ERVK-6 ERVK-21 ERVK-19 ERVS71-1

5.97e-0810145412970426
Pubmed

A revised nomenclature for transcribed human endogenous retroviral loci.

ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19 ERVK-25 ERVS71-1

1.43e-0794145721542922
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

AKNA FGFRL1 IRS1 EDC4 FHIP1B ZZEF1 NPHP4 TLK1 C2CD3 IGF2R DST TULP4 HELZ2 CPSF1 HERC2 ZC3H7B TOP3A AHNAK2 BAHCC1

1.89e-0711051451935748872
Pubmed

Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region.

LRRC37A3 LRRC37A2 LRRC37A

2.83e-074145322419166
Pubmed

Genetic mapping of the mouse ferritin light chain gene and 11 pseudogenes on 11 mouse chromosomes.

CD1D VCAN DHFR DHFR2 ALDH3A2

3.99e-073614559457670
Pubmed

Quantitation of HERV-K env gene expression and splicing in human breast cancer.

ERVK-6 ERVK-21 ERVK-19

7.05e-075145312629516
Pubmed

Human endogenous retrovirus HERV-K(HML-2) proviruses with Rec protein coding capacity and transcriptional activity.

ERVK-6 ERVK-9 ERVK-19

1.41e-066145315063128
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

PDS5B ZNF184 RAD51AP1 LIG3 RIF1 NFATC2IP RECQL5 KDM2B SGO2 HERC2 DDX24 ZHX1 CUX1

1.77e-066081451336089195
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

MXRA5 LRRC37A3 CDS2 DNAH2 LMOD2 AP3M1 DNAH7 NOSIP LIG3 SALL1 KDM2B CUX1 AHNAK2

2.99e-066381451331182584
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

TNIK CCDC50 FHIP1B DNAH7 ZC3H7A IBTK C2CD3 IGF2R IQCC CAPN7 HERC2 PIBF1 CPLANE1 PPP6R3 BORA

3.06e-068531451528718761
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

PDS5B XRN2 DHX57 EDC4 RIF1 IGF2R DST HELZ2 CPSF1 HERC2 EIF4G3 DDX24 PPP6R3

3.84e-066531451322586326
Pubmed

The Cspg2 gene, disrupted in the hdf mutant, is required for right cardiac chamber and endocardial cushion formation.

VCAN DHFR DHFR2

3.91e-06814539758703
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

DNAH2 AKNA CCDC50 DNAH7 RIF1 DST NYNRIN TECPR1

6.52e-06233145837704626
Pubmed

A human MAP kinase interactome.

CCDC88B ZC3H7A RIF1 TLK1 DST YY1AP1 HERC2 PIBF1 CPLANE1 ZHX1 CUX1

6.68e-064861451120936779
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

XRN2 NOSIP ZC3H7A SALL1 NFATC2IP IQCC RECQL5 KDM2B YY1AP1 ALDH3A2 TOP3A PPP6R3

7.17e-065881451238580884
Pubmed

Human transcription factor protein interaction networks.

XRN2 GON4L EDC4 ZNF691 NOSIP LIG3 RIF1 DST SALL1 RECQL5 CPSF1 KDM2B YY1AP1 HERC2 DDX24 ZHX1 CUX1 PPP6R3 BRMS1

8.28e-0614291451935140242
Pubmed

The C-terminal domain of Mad-like signal transducers is sufficient for biological activity in the Xenopus embryo and transcriptional activation.

VCAN DHFR DHFR2

8.34e-061014539076683
Pubmed

Evolutionary dynamism of the primate LRRC37 gene family.

LRRC37A3 LRRC37A2 LRRC37A

8.34e-0610145323064749
Pubmed

Dihydrofolate reductase activity controls neurogenic transitions in the developing neocortex.

DHFR DHFR2 CUX1

1.52e-0512145337665322
Pubmed

Cux1 and Cux2 selectively target basal and apical dendritic compartments of layer II-III cortical neurons.

CUX2 CUX1

1.73e-052145225059644
Pubmed

Cux-1 and Cux-2 control the development of Reelin expressing cortical interneurons.

CUX2 CUX1

1.73e-052145218327765
Pubmed

A unique variant of a homeobox gene related to Drosophila cut is expressed in mouse testis.

CUX2 CUX1

1.73e-05214528879483
Pubmed

The Justy mutation identifies Gon4-like as a gene that is essential for B lymphopoiesis.

GON4L YY1AP1

1.73e-052145220530203
Pubmed

Isolation and characterization of murine Cds (CDP-diacylglycerol synthase) 1 and 2.

CDS1 CDS2

1.73e-052145216023307
Pubmed

CUX2 deficiency causes facilitation of excitatory synaptic transmission onto hippocampus and increased seizure susceptibility to kainate.

CUX2 CUX1

1.73e-052145235581205
Pubmed

Distinct properties of the two isoforms of CDP-diacylglycerol synthase.

CDS1 CDS2

1.73e-052145225375833
Pubmed

Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.

ERVK-6 ERVK-19

1.73e-05214529060628
Pubmed

Newly identified Gon4l/Udu-interacting proteins implicate novel functions.

GON4L YY1AP1

1.73e-052145232848183
Pubmed

Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses.

ERVK-6 ERVK-19

1.73e-05214529460924
Pubmed

CDP-DAG synthase 1 and 2 regulate lipid droplet growth through distinct mechanisms.

CDS1 CDS2

1.73e-052145231548309
Pubmed

The transcriptional regulator GON4L is required for viability and hematopoiesis in mice.

GON4L YY1AP1

1.73e-052145233864850
Pubmed

A gene mutated in nephronophthisis and retinitis pigmentosa encodes a novel protein, nephroretinin, conserved in evolution.

NPHP1 NPHP4

1.73e-052145212205563
Pubmed

Isolation and chromosomal localization of two human CDP-diacylglycerol synthase (CDS) genes.

CDS1 CDS2

1.73e-05214529806839
Pubmed

CDP-diacylglycerol synthases regulate the growth of lipid droplets and adipocyte development.

CDS1 CDS2

1.73e-052145226946540
Pubmed

Expression of a cut-related homeobox gene in developing and polycystic mouse kidney.

CUX2 CUX1

1.73e-05214528840273
Pubmed

Functional characterization of the C. elegans nephrocystins NPHP-1 and NPHP-4 and their role in cilia and male sensory behaviors.

NPHP1 NPHP4

1.73e-052145215817158
Pubmed

Nephrocystin-1 and nephrocystin-4 are required for epithelial morphogenesis and associate with PALS1/PATJ and Par6.

NPHP1 NPHP4

1.73e-052145219755384
Pubmed

Cross Talk Between GH-Regulated Transcription Factors HNF6 and CUX2 in Adult Mouse Liver.

CUX2 ONECUT1

1.73e-052145226218442
Pubmed

Cux1 Enables Interhemispheric Connections of Layer II/III Neurons by Regulating Kv1-Dependent Firing.

CUX2 CUX1

1.73e-052145226804994
Pubmed

Identification of a tissue-specific putative transcription factor in breast tissue by serological screening of a breast cancer library.

ANKRD30B ANKRD30A

1.73e-052145211280766
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

TNIK PDS5B EPS15 KDM4C APOOL MBD1 CDS2 ZNF184 PHTF2 EDC4 SNAP47 CBLIF DNAH17 RNF10 TMEM30A SGO2 ARAP2

1.78e-0512421451730973865
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

XRN2 GON4L DHX57 ZZEF1 LIG3 IBTK DST CHTF18 OSBPL10 YY1AP1 ZC3H7B TOP3A

1.94e-056501451238777146
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH2 DNAH7 DNAH17

2.50e-051414539373155
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

PDS5B CUX2 ASH1L DNAH2 ANKRD30B CCDC50 DHX57 ZC3H7A RAD51AP1 TLK1 C2CD3 DST FAM161A FAM186A ANKRD30A EIF4G3 CUX1 BAHCC1

3.35e-0514421451835575683
Pubmed

Translocation of a long amino-terminal domain through ER membrane by following signal-anchor sequence.

DHFR DHFR2

5.16e-053145216107879
Pubmed

Assignment of two rat dihydrofolate (DHFR) genes to chromosomes 2 and 4.

DHFR DHFR2

5.16e-05314522323224
Pubmed

Dihydrofolate reductase deficiency causing megaloblastic anemia in two families.

DHFR DHFR2

5.16e-05314521060915
Pubmed

Early B Cell Progenitors Deficient for GON4L Fail To Differentiate Due to a Block in Mitotic Cell Division.

GON4L YY1AP1

5.16e-053145228381640
Pubmed

New polymorphic markers in the vicinity of the pearl locus on mouse chromosome 13.

DHFR DHFR2

5.16e-05314528903722
Pubmed

The gene mutated in juvenile nephronophthisis type 4 encodes a novel protein that interacts with nephrocystin.

NPHP1 NPHP4

5.16e-053145212244321
Pubmed

An active second dihydrofolate reductase enzyme is not a feature of rat and mouse, but they do have activity in their mitochondria.

DHFR DHFR2

5.16e-053145225980602
Pubmed

Isolation and characterization of a variant dihydrofolate reductase cDNA from methotrexate-resistant murine L5178Y cells.

DHFR DHFR2

5.16e-05314522263462
Pubmed

Isolation and expression of an altered mouse dihydrofolate reductase cDNA.

DHFR DHFR2

5.16e-05314526573667
Pubmed

Expression and amplification of engineered mouse dihydrofolate reductase minigenes.

DHFR DHFR2

5.16e-05314526835212
Pubmed

Arrested Hematopoiesis and Vascular Relaxation Defects in Mice with a Mutation in Dhfr.

DHFR DHFR2

5.16e-053145226830229
Pubmed

Role of the AAA protease Yme1 in folding of proteins in the intermembrane space of mitochondria.

DHFR DHFR2

5.16e-053145222993211
Pubmed

Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.

ERVK-6 ERVK-19

5.16e-053145210516026
Pubmed

New insights into DHFR interactions: analysis of Pneumocystis carinii and mouse DHFR complexes with NADPH and two highly potent 5-(omega-carboxy(alkyloxy) trimethoprim derivatives reveals conformational correlations with activity and novel parallel ring stacking interactions.

DHFR DHFR2

5.16e-053145217019704
Pubmed

Dihydrofolate reductase protects endothelial nitric oxide synthase from uncoupling in tetrahydrobiopterin deficiency.

DHFR DHFR2

5.16e-053145221402147
Pubmed

Unbalanced growth in mouse cells with amplified dhfr genes.

DHFR DHFR2

5.16e-05314529650531
Pubmed

Structure and genomic organization of the mouse dihydrofolate reductase gene.

DHFR DHFR2

5.16e-05314526244105
Pubmed

Nephrocystin-4 regulates Pyk2-induced tyrosine phosphorylation of nephrocystin-1 to control targeting to monocilia.

NPHP1 NPHP4

5.16e-053145221357692
Pubmed

Human RecQ5beta, a large isomer of RecQ5 DNA helicase, localizes in the nucleoplasm and interacts with topoisomerases 3alpha and 3beta.

RECQL5 TOP3A

5.16e-053145210710432
Pubmed

Transgenic mice expressing the tyr22 variant of murine DHFR: protection of transgenic marrow transplant recipients from lethal doses of methotrexate.

DHFR DHFR2

5.16e-05314529357973
Pubmed

OC-2, a novel mammalian member of the ONECUT class of homeodomain transcription factors whose function in liver partially overlaps with that of hepatocyte nuclear factor-6.

ONECUT1 ONECUT3

5.16e-05314529915796
Pubmed

SENIOR-LØKEN SYNDROME: A Case Series and Review of the Renoretinal Phenotype and Advances of Molecular Diagnosis.

NPHP1 NPHP4

5.16e-053145233512896
Pubmed

Phenotypic expression in E. coli of a DNA sequence coding for mouse dihydrofolate reductase.

DHFR DHFR2

5.16e-0531452360074
Pubmed

Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirus.

ERVK-6 ERVK-9

5.16e-05314529971820
Pubmed

OC-3, a novel mammalian member of the ONECUT class of transcription factors.

ONECUT1 ONECUT3

5.16e-053145211944891
Pubmed

Gene amplification and drug resistance in cultured murine cells.

DHFR DHFR2

5.16e-0531452715457
Pubmed

Selective multiplication of dihydrofolate reductase genes in methotrexate-resistant variants of cultured murine cells.

DHFR DHFR2

5.16e-0531452627542
Pubmed

The Justy mutant mouse strain produces a spontaneous murine model of salivary gland cancer with myoepithelial and basal cell differentiation.

GON4L YY1AP1

5.16e-053145223608756
Pubmed

Structure of amplified normal and variant dihydrofolate reductase genes in mouse sarcoma S180 cells.

DHFR DHFR2

5.16e-05314526282858
Pubmed

In vitro mutations in dihydrofolate reductase that confer resistance to methotrexate: potential for clinical application.

DHFR DHFR2

5.16e-05314529554740
Pubmed

ONECUT transcription factors induce neuronal characteristics and remodel chromatin accessibility.

ONECUT1 ONECUT3

5.16e-053145231049588
Pubmed

The HIP1 binding site is required for growth regulation of the dihydrofolate reductase gene promoter.

DHFR DHFR2

5.16e-05314521545788
Pubmed

Relation of folic acid reductase to amethopterin resistance in cultured mammalian cells.

DHFR DHFR2

5.16e-053145213710631
Pubmed

Knockout of dihydrofolate reductase in mice induces hypertension and abdominal aortic aneurysm via mitochondrial dysfunction.

DHFR DHFR2

5.16e-053145230954686
Pubmed

Assignment of the human dihydrofolate reductase gene to the q11----q22 region of chromosome 5.

DHFR DHFR2

5.16e-05314526504041
Pubmed

Influence of substrate binding on the mechanical stability of mouse dihydrofolate reductase.

DHFR DHFR2

5.16e-053145216183885
Pubmed

The former annotated human pseudogene dihydrofolate reductase-like 1 (DHFRL1) is expressed and functional.

DHFR DHFR2

5.16e-053145221876184
Pubmed

Evidence of oligogenic inheritance in nephronophthisis.

NPHP1 NPHP4

5.16e-053145217855640
Pubmed

Interaction of ciliary disease protein retinitis pigmentosa GTPase regulator with nephronophthisis-associated proteins in mammalian retinas.

NPHP1 NPHP4

5.16e-053145220664800
Pubmed

Nucleotide sequence surrounding multiple polyadenylation sites in the mouse dihydrofolate reductase gene.

DHFR DHFR2

5.16e-05314526121807
Pubmed

Transcriptional regulation of the dihydrofolate reductase/rep-3 locus.

DHFR DHFR2

5.16e-05314527987046
Pubmed

The amino acid sequence of dihydrofolate reductase from the mouse lymphoma L1210.

DHFR DHFR2

5.16e-0531452762074
Pubmed

Glucocorticoids regulate expression of dihydrofolate reductase cDNA in mouse mammary tumour virus chimaeric plasmids.

DHFR DHFR2

5.16e-05314526272123
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

EPS15 MBD1 GON4L CCDC50 DHX57 EDC4 ZC3H7A RIF1 DST RECQL5 HELZ2 KDM2B HERC2 EIF4G3 ZC3H7B ALDH3A2 ZHX1 PPP6R3

5.43e-0514971451831527615
Pubmed

Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.

ERVK-21 ERVK-9 ERVK-25

5.53e-0518145318664271
Pubmed

An integrated genetic map of the pearl locus of mouse chromosome 13.

VCAN DHFR DHFR2

6.55e-051914538828042
Pubmed

Congenital Hepatic Fibrosis Overview ─ RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY

NPHP1 EVC2 NPHP4 CPLANE1

6.72e-0552145420301743
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

MBD1 IRS1 EDC4 DNAH7 C2CD3 DST RNF10 OSBPL10 NCOA7 EIF4G3 PIBF1 ARAP2 AHNAK2

6.89e-058611451336931259
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

TNIK NPHP4 DNAH7 NOSIP MTMR11 FAM186A DHFR SERTAD4 HERC2

7.16e-05420145928065597
Pubmed

Two Pairs of ON and OFF Retinal Ganglion Cells Are Defined by Intersectional Patterns of Transcription Factor Expression.

KCNIP3 ONECUT1 SALL1 ONECUT3

7.24e-0553145427210758
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

PDS5B XRN2 DHX57 ZC3H7A LIG3 IBTK RIF1 SGO2 HERC2 EIF4G3 ZC3H7B DDX24

8.59e-057591451235915203
Pubmed

Characterization of the nephrocystin/nephrocystin-4 complex and subcellular localization of nephrocystin-4 to primary cilia and centrosomes.

NPHP1 NPHP4

1.03e-044145215661758
Pubmed

Biochemical characterization of the mammalian Cux2 protein.

CUX2 CUX1

1.03e-044145215656993
Pubmed

Endothelial Nitric Oxide Synthase-Derived Nitric Oxide Prevents Dihydrofolate Reductase Degradation via Promoting S-Nitrosylation.

DHFR DHFR2

1.03e-044145226381869
Pubmed

Assignment of genes encoding dihydrofolate reductase and hexosaminidase B to Mus musculus chromosome 13.

DHFR DHFR2

1.03e-04414522947337
Cytoband6q14.1

ERVK-9 IBTK TMEM30A

5.71e-052414336q14.1
GeneFamilyCUT class homeoboxes and pseudogenes

CUX2 ONECUT1 ONECUT3 CUX1

2.87e-089724527
GeneFamilyDyneins, axonemal

DNAH2 DNAH7 DNAH17

3.96e-0517723536
GeneFamilyZinc fingers CXXC-type

MBD1 KDM2B

1.01e-0312722136
GeneFamilyEF-hand domain containing

EPS15 KCNIP3 ZZEF1 DNAH7 DST

1.80e-03219725863
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

ZZEF1 HERC2

2.30e-031872291
GeneFamilyAnkyrin repeat domain containing

ANKRD30B IBTK ANKRD30A TRPV4 ARAP2

2.78e-03242725403
GeneFamilyImmunoglobulin like domain containing|Semaphorins

SEMA6D SEMA3B

2.84e-0320722736
GeneFamilyPHD finger proteins|Lysine demethylases

KDM4C KDM2B

4.08e-0324722485
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

PDS5B EPS15 KDM4C CDS2 IRS1 ZZEF1 IBTK RIF1 TLK1 C2CD3 IGF2R DST EIF4G3 PIBF1 CUX1 ARAP2

1.19e-0585613816M4500
CoexpressionWANG_RESPONSE_TO_BEXAROTENE_DN

EPS15 MSC MAP6 RAD51AP1

1.81e-05301384M1264
CoexpressionWANG_RESPONSE_TO_BEXAROTENE_DN

EPS15 MSC MAP6 RAD51AP1

1.81e-05301384MM532
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#2_top-relative-expression-ranked_1000

PDS5B ASH1L CCDC50 FAM171B IBTK RIF1 NFATC2IP VCAN MME HERC2 CPLANE1 CUX1

1.47e-0633013612DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k2_1000
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_top-relative-expression-ranked_1000

TNIK PDS5B CUX2 CCDC50 FAM171B KCNIP3 RAD51AP1 IBTK C2CD3 IGF2R DST VCAN NCOA7 SGO2 CPLANE1 ZHX1 CUX1 BORA

2.21e-0677213618gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#3_top-relative-expression-ranked_1000

CCDC50 FAM171B NEDD9 LIG3 IBTK C2CD3 NFATC2IP VCAN MME HERC2 CPLANE1 CUX1

4.66e-0636913612DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k3_1000
CoexpressionAtlasDevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#5_top-relative-expression-ranked_1000

APOOL CCDC50 NEDD9 LIG3 IBTK RIF1 TLK1 C2CD3 MME CPLANE1 CUX1

1.20e-0533913611gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_1000_k5
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#5_top-relative-expression-ranked_500

CCDC50 NEDD9 IBTK VCAN MME HERC2 CPLANE1 CUX1

3.65e-051941368DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k5_500
CoexpressionAtlasDevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#5_top-relative-expression-ranked_1000

CCDC50 IBTK RIF1 C2CD3 VCAN NCOA7 CUX1

4.38e-051461367gudmap_developingKidney_e15.5_Cap mesenchyme_1000_k5
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_top-relative-expression-ranked_500

CCDC50 FAM171B NEDD9 IBTK DST SALL1 VCAN MME HERC2 CPLANE1 CUX1

6.54e-0540813611DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_500
CoexpressionAtlasDevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#5_top-relative-expression-ranked_500

CCDC50 NEDD9 IBTK C2CD3 MME CPLANE1 CUX1

6.67e-051561367gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_500_k5
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_1000

PDS5B CUX2 ASH1L CCDC50 FAM171B IBTK RIF1 SALL1 NFATC2IP VCAN SERTAD4 MME HERC2 CPLANE1 CUX1 ARAP2

7.11e-0581813616DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_1000
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#4_top-relative-expression-ranked_200

CCDC50 VCAN CPLANE1 CUX1

1.23e-04401364gudmap_developingKidney_e15.5_Ureteral Smooth Musc_200_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_e15.5_Urothelium_emap-28091_k-means-cluster#1_top-relative-expression-ranked_1000

CCDC50 IBTK C2CD3 NFATC2IP HERC2 CPLANE1 CUX1

1.27e-041731367gudmap_developingLowerUrinaryTract_e15.5_Urothelium_1000_k1
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#4_top-relative-expression-ranked_1000

CCDC50 LIG3 IBTK C2CD3 TULP4 VCAN MME HERC2 CPLANE1 CUX1

1.92e-0438513610gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_top-relative-expression-ranked_1000

CCDC50 FAM171B NEDD9 LIG3 IBTK C2CD3 DST SALL1 NFATC2IP VCAN MME HERC2 CPLANE1 CUX1 ARAP2

2.08e-0480613615DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_1000
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_top-relative-expression-ranked_500

TNIK CCDC50 KCNIP3 IBTK VCAN NCOA7 CPLANE1 ZHX1 CUX1 BORA

2.26e-0439313610gudmap_developingKidney_e15.5_Ureteral Smooth Musc_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#5_top-relative-expression-ranked_1000

PDS5B ASH1L CCDC50 IBTK TULP4 VCAN SNX27 HERC2 CPLANE1 CUX1

2.45e-0439713610gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000_k5
CoexpressionAtlasDevelopingKidney_e15.5_Medullary collecting duct_emap-28063_k-means-cluster#4_top-relative-expression-ranked_1000

GON4L CCDC50 LIG3 IBTK C2CD3 VCAN CPLANE1 CUX1

2.84e-042611368gudmap_developingKidney_e15.5_Medullary collecting duct_1000_k4
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-BM_CD8_+_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRK4 DHX57 PRRT3 OSBPL10 PIBF1 CPLANE1 TECPR1

6.91e-07160138755f599df6e3b7a5a505df4b094c834281311d94a
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-mature_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRK4 DHX57 PRRT3 OSBPL10 PIBF1 CPLANE1 TECPR1

6.91e-071601387296e53e1e0786346d38db2d4188b9a1c0430627b
ToppCellfacs-Lung-EPCAM-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKNA MTMR11 PTAR1 TBCK OSBPL10 NCOA7 ZHX1

8.16e-0716413871d0d88132baaa3154c3e6e4ef0aff795afab08a2
ToppCellfacs-Lung-EPCAM-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKNA MTMR11 PTAR1 TBCK OSBPL10 NCOA7 ZHX1

8.16e-071641387bd2e10b015d5e6a338675500ec5d81dc39583b3e
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAD51AP1 RIF1 CHTF18 DHFR HELZ2 OSBPL10 SGO2

1.12e-0617213872b6cd84c946b1e800caba452ae70145ea285fec1
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNIK XRN2 NOSIP ZC3H7A TLK1 NCOA7 ARAP2

2.18e-06190138791ba66d4b56c59523485b17738e93f14bb00afa4
ToppCellNS-moderate-d_16-33-Epithelial-FOXN4+|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NPHP1 DNAH7 IQCC FAM161A DHFR SERTAD4 SGO2

2.18e-061901387250ca4a605c1cccd77d23383e4fe6f91cf3609ba
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.Cadm2_(Cadm2_state)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

PGBD1 C1orf105 SEMA3B VSIG10L ZC3H7B

5.70e-0682138501a4d47d9e0dee68a5277ed1534338cec80f75d1
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.Cadm2_(Cadm2_state)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

PGBD1 C1orf105 SEMA3B VSIG10L ZC3H7B

5.70e-06821385c1489097c291f413f3cfa5e26f8182ec872328fd
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

DNAH7 NEDD9 IGF2R C1orf105 SERTAD4 ARAP2

7.72e-0615113860cc2f4aec3dae4603fa831f22c40f897e68b34e2
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

DNAH7 NEDD9 IGF2R C1orf105 SERTAD4 ARAP2

7.72e-061511386b545823113a3450c5f841f7de48bf0937593544f
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th|T/NK_cells / Location, Cell class and cell subclass

GRK4 NEDD9 VCAN DHFR2 OSBPL10 JRKL

1.67e-05173138642c911ed16fabdabef063830e8407192d8bde950
ToppCellnormal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells|normal_Lymph_Node / Location, Cell class and cell subclass

CUX2 KCTD19 LRRC37A3 CCDC50 LRRC37A CSF2RB

1.79e-05175138629fbdfe1d3bfcb063be2bced0128a33176c5b78f
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CUX2 COL11A1 CCDC168 DNAH7 SEMA6D MME

1.97e-0517813860e1bedf991189d0ef9b40dac9281bdf4739333a1
ToppCellCOVID-19-kidney-tDL|COVID-19 / Disease (COVID-19 only), tissue and cell type

HGD MYO7B SLC13A3 PAH OSBPL10 MME

2.09e-051801386864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK MYO7B SLC13A3 PAH TRPV4 MME

2.16e-0518113869542c19edc9bd2cba68c01c2a8407705398e3011
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK MYO7B SLC13A3 PAH TRPV4 MME

2.16e-0518113868f04f8cac5d705dc5f6cf6f4516d6e45b0aa4ae5
ToppCellwk_20-22-Mesenchymal-Chondrocyte-Resting_chondrocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

COL11A1 MXRA5 FGFRL1 ENTPD5 SERTAD4 TRPV4

2.23e-05182138603a5a02acd48f0eb210485348bfe0cd21f486215
ToppCellCOVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type

HGD MYO7B SLC13A3 DNAH7 SALL1 OSBPL10

2.30e-0518313866878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

ASH1L OAS2 RIF1 DST HELZ2 NCOA7

2.30e-0518313868f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellCOVID-19-kidney-PCT-S1/S2|kidney / Disease (COVID-19 only), tissue and cell type

HGD MYO7B SLC13A3 PAH ENTPD5 MME

2.37e-051841386dc71f22583fc54b89b242cbb602f4bbe86f576ec
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CCDC168|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HGD CDS1 CUX2 CCDC168 HERC2P3 CUX1

2.44e-0518513865a0340c25196453f19e424d346efbf66d2c53ac3
ToppCellNS-moderate-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NPHP1 MARCHF10 MAP6 DNAH2 SLC13A3 DNAH7

2.52e-05186138685787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCellCOVID-19-kidney-Mito-rich_PCT|kidney / Disease (COVID-19 only), tissue and cell type

TNIK MYO7B SLC13A3 DHFR PAH MME

2.59e-051871386738ec2611b4be6a08eedad16b57fba84e1f11fef
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO7B SLC13A3 PAH TRPV4 MME CUX1

2.67e-051881386f3edcefeef2ce19086032d98b243c02a6d542b38
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK ENOSF1 MYO7B SLC13A3 PAH OSBPL10

2.92e-0519113863c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK ENOSF1 MYO7B SLC13A3 PAH OSBPL10

2.92e-0519113861c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

COL11A1 MXRA5 FGFRL1 SERTAD4 LOXL4 TRPV4

3.01e-0519213863a6f2c255da46a0b0f5b657b0f56f3d7798ae85a
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MARCHF10 DNAH2 DNAH7 FAM161A CPLANE1 AHNAK2

3.10e-051931386ea345d34440b25f65358a53dc72831998d1c3620
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TNIK KDM4C AKNA NFATC2IP DDX24 ARAP2

3.10e-0519313869337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ENOSF1 SLC13A3 DNAH7 TRPV4 MME CUX1

3.10e-05193138682e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCellmoderate-Epithelial-FOXN4+|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

NPHP1 DNAH7 FAM161A DHFR SGO2 CPLANE1

3.19e-0519413865dffa578149104dda33774361e9e77b227b5f1ce
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-4|TCGA-Prostate / Sample_Type by Project: Shred V9

EVC2 KCNIP3 MTMR11 DST NYNRIN TRPV4

3.28e-0519513865562665dd3beb70e2358aa32611a337bef5731c1
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

NPHP1 MARCHF10 MAP6 DNAH2 SLC13A3 DNAH7

3.28e-0519513863486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

NPHP1 MARCHF10 MAP6 DNAH2 SLC13A3 DNAH7

3.28e-051951386e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_submucosal-gland|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

NYNRIN DHFR RECQL5 OSBPL10 MME JRKL

3.78e-05200138668b0f987c4fb8078675475f4f1e71302f832ef69
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_submucosal-gland-SMG_Duct|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

NYNRIN DHFR RECQL5 OSBPL10 MME JRKL

3.78e-0520013861b527bebbca1ef8c52449e40beb9358e37494e04
ToppCellNS-critical-d_0-4-Myeloid-pDC|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CUX2 KCTD19 MYO7B IRS1 SGO2

8.63e-0514413850fde5cd82df9b90aefde19275cff6c2ec3c9d5cb
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF184 ANKRD30B RAD51AP1 CHTF18 C1orf105

9.51e-051471385c0f62ed3312a33921476e89844486e09326485b7
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-7|TCGA-Liver / Sample_Type by Project: Shred V9

SRARP SLC13A3 IRS1 ASPSCR1 MME

1.37e-04159138570288df54adab167c0f50675128619299077db11
ToppCelldroplet-Liver-Hepatocytes-21m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGD PAH LOXL4 MME ALDH3A2

1.59e-041641385c9866a289e120be4066e66275c3beb97ba67cca4
ToppCelldroplet-Liver-Hepatocytes-21m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGD PAH LOXL4 MME ALDH3A2

1.59e-04164138590afae3cca108ebfb44ff2ec4adcbb8c68a0bdf2
ToppCelldroplet-Liver-Hepatocytes-21m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGD PAH LOXL4 MME ALDH3A2

1.68e-0416613854b63ecedf21285974f0d188979fcdced27bf9ef9
ToppCelldroplet-Liver-Hepatocytes-21m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGD PAH LOXL4 MME ALDH3A2

1.68e-041661385d6d29b0dc1ef471b1227495f349963ab37f22ec4
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CUX2 DNAH2 SLC13A3 PAH MME

1.73e-0416713853edb0570e583bb527165bcd8a4c25a042054043b
ToppCell343B-Myeloid-Dendritic-cDC_proliferating_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PGBD1 RAD51AP1 IQCC DHFR ONECUT3

1.73e-0416713853461d14e36f09ddc6ee5549ca4797e16d3f37fcc
ToppCellB_cells-pDCs|World / Immune cells in Kidney/Urine in Lupus Nephritis

CUX2 KCTD19 CCDC50 CSF2RB RECQL5

1.78e-041681385dc8f94424f60ab56facdcffa969e7f3466ee1b6e
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PGBD1 LIG3 VCAN CPLANE1 ZHX1

1.78e-041681385d69452e2cfeb74023b5cf3d09064d7dcad0008ec
ToppCell10x5'-lymph-node_spleen-Myeloid_Dendritic-pDC|lymph-node_spleen / Manually curated celltypes from each tissue

CUX2 KCTD19 CCDC50 CSF2RB BAHCC1

1.78e-041681385cfed36fece51871a5abbcde71f6bd5e7212357ff
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL11A1 MSC VCAN DHFR LOXL4

1.83e-041691385335619507857383c3b0b507cdf05d786ed59e585
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPHP1 ENOSF1 MARCHF10 DNAH7 CPLANE1

1.83e-041691385fba841664939c771881ba97f14ef1df6635c04ff
ToppCellNS-critical-LOC-Epithelial-FOXN4+|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NPHP1 MXRA5 DNAH7 IQCC SERTAD4

1.88e-041701385f6a0162bb690dbc19ff1cec64cb933744ad3b496
ToppCellBasal_cells-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

MXRA5 EVC2 GRK4 TRPV4 ARAP2

1.88e-041701385776d4224a682b6c648041827efd69794f88906f0
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_HSPB3|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CUX2 COL11A1 CCDC168 DNAH7 SEMA6D

1.88e-041701385985c6c9e3c593ed0628a481f06c2c91b2ab5d746
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MXRA5 DST SERTAD4 LOXL4 AHNAK2

1.88e-0417013850cc20322cb3e3e7bbd4daad8785c99f80e355c16
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-Lgr5+_undifferentiated_cell_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEP57L1 DNAH2 PGBD1 NFATC2IP LOXL4

1.88e-04170138545de83a2231208b8e1f21061d0b91644b4a3ba93
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MXRA5 DST SERTAD4 LOXL4 AHNAK2

1.88e-0417013852d880223d01bde4bf777bd6f50b7d2768489075f
ToppCell356C-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

EPS15 CSF2RB KDM2B ONECUT3 ARAP2

1.88e-041701385513d9036aa41d4d902da8baa66a66206abb6f3b0
ToppCellwk_20-22-Mesenchymal-Chondrocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

COL11A1 MXRA5 FGFRL1 SLC13A3 TRPV4

1.93e-041711385d2938639e9a7c349e5a6ec61724222f9d127c89f
ToppCellCOVID-pDC|COVID / Condition, Cell_class and T cell subcluster

CUX2 KCTD19 CCDC50 IGHD MME

1.98e-0417213853ecbb000495dde32f6153ef6bdea9c8802ff3985
ToppCellCOVID-pDC-|COVID / Condition, Cell_class and T cell subcluster

CUX2 KCTD19 CCDC50 IGHD MME

1.98e-041721385a7827faa1afab51fdaf0cb1a2babcd2e00d411e5
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

FGFRL1 CCDC50 DHFR2 ENTPD5 ZC3H7B

2.04e-0417313857e2149205e119cec4f5099c83c85d1e13470137a
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP6 STAP2 LOXL4 SGO2 ALDH3A2

2.09e-0417413859d5dcd46cf346c381dea68ada6665f7fb68114a3
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP6 STAP2 LOXL4 SGO2 ALDH3A2

2.09e-04174138553cec5c666c45278a71c21dd9c62a052a97e0fdf
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CUX2 CCDC168 SEMA6D PAH MME

2.09e-041741385b3cd22e717d178269e6d5bd5ed7b2d945cd8ea25
ToppCellCOVID-19_Mild-Neu_3|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients

KDM4C MBD1 GON4L NOSIP CD1D

2.20e-0417613852049767fd591045cfcf5b1071d80798e52843f27
ToppCell3'_v3-blood-Mast-Mast_cells|blood / Manually curated celltypes from each tissue

CEP57L1 KCNIP3 CSF2RB VSIG10L RNF10

2.20e-041761385b9da3deaf62622d47eb30b6be7548253eee95597
ToppCellwk_08-11-Mesenchymal-Chondrocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

COL11A1 MXRA5 FGFRL1 SERTAD4 MME

2.20e-0417613851af28b701c4598ce761f85adbd5d79e4918d265a
ToppCellAT1_cells-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

ANKRD30B NEDD9 DST SEMA3B AHNAK2

2.26e-0417713853128b8d04687acee1ac4190b2569d6328b98eaf3
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HGD CUX2 CCDC168 PAH CUX1

2.26e-041771385f902600c639087664316b3cf30cab243bc3d1c5c
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-chondrocyte|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

COL11A1 FGFRL1 SERTAD4 LOXL4 TRPV4

2.26e-041771385915b848d789051a1c3bc6f6dc86955bb752276ab
ToppCellSomatosensory_Cortex_(S1)|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HGD CUX2 CCDC168 SEMA6D CUX1

2.38e-04179138582348bf56a4525b2f485696cab5b2ea6e96c2f91
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPHP1 CDS1 IQCC DHFR SGO2

2.45e-0418013850c146e80d55d18b6988dd21b1da635801bd3140c
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPHP1 CDS1 IQCC DHFR SGO2

2.45e-041801385e9af22beae2f3c7fe213b4e19df84abfd2453433
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPHP1 CDS1 IQCC DHFR SGO2

2.45e-04180138511455ba704ac73f69b474845136cfecec6a88349
ToppCellCOVID-19-kidney-Stressed_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

HGD MYO7B SLC13A3 PAH MME

2.51e-0418113856980ea624151da32b7f537f263e40fcb87a02e81
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSC CHTF18 DHFR SGO2 BORA

2.57e-0418213853948422707d6d5e021bcd7158e2eb69143613f62
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-Proliferating_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSC CHTF18 DHFR SGO2 BORA

2.57e-041821385fe46819c153a81911864473badc794f243705f98
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MARCHF10 MAP6 DNAH2 SLC13A3 DNAH7

2.77e-0418513855e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellCOVID-19-kidney-Mito-rich_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

HGD SLC13A3 DHFR PAH MME

2.77e-0418513851bbc2ba8a20f72f61981b1301cdd6018cdd9150d
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NPHP1 MARCHF10 MAP6 DNAH2 DNAH7

2.84e-04186138576033438426d8f9c72cd6691a7baf92104c9f03d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO7B SLC13A3 TRPV4 MME CUX1

2.84e-041861385a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC28A3 ONECUT1 PAH SEMA3B MME

2.91e-0418713859aa411ae9b5a923378a5daebb8bb2fc2613f2510
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-23|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TNIK MSC LMOD2 PRRT3 CUX1

2.91e-04187138569b47f00598d647e2a99427ebddf42c339428e47
ToppCellCOVID-19-kidney-tDL|kidney / Disease (COVID-19 only), tissue and cell type

TNIK MYO7B SLC13A3 OSBPL10 MME

2.91e-041871385d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCellhuman_hepatoblastoma-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

HGD CUX2 SLC13A3 TBCK PAH

2.91e-041871385f3e37c18ac6471c7992609bbddfa4975571c815c
ToppCellCOVID-19-kidney-Stressed_PCT|kidney / Disease (COVID-19 only), tissue and cell type

TNIK MYO7B SLC13A3 PAH MME

2.91e-041871385acd305475f3609800af0d7bc68d83ef41228080b
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7|TCGA-Colorectal / Sample_Type by Project: Shred V9

COL11A1 MXRA5 LRRC37A3 IGF2R VCAN

2.99e-04188138514bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-chondrocyte|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL11A1 FGFRL1 SERTAD4 LOXL4 TRPV4

2.99e-0418813855a89587ee6f2b4dc14244bd88bb31efb81c50dbe
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO7B SLC13A3 PAH TRPV4 MME

2.99e-0418813850792432cd4c564dea1102241ea9884f7ced7658c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK MYO7B SLC13A3 PAH MME

3.06e-041891385204ab61ae606b2d9be0cb6bf6a83a011740693a8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK MYO7B SLC13A3 PAH MME

3.06e-04189138513fd07cc408a9486f61a7b2c3a132c52d14b438d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK MYO7B VCAN PAH OSBPL10

3.06e-04189138528b502611829e4a24caff2562545c7db97686099
ToppCellCOVID-19-kidney-PCT-S2|kidney / Disease (COVID-19 only), tissue and cell type

TNIK MYO7B SLC13A3 PAH OSBPL10

3.06e-0418913850be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPHP1 IQCC FAM161A DHFR SGO2

3.14e-0419013850adb24dafa077156bbc73a8d8cbf3d9eeb6e08df
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPHP1 IQCC FAM161A DHFR SGO2

3.14e-04190138505455775845f4ded5c27e7b83242078d23162aaf
ToppCellpdx-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

PDS5B RAD51AP1 NFATC2IP CHTF18 SGO2

3.14e-041901385d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCellCOPD-Lymphoid-T_Regulatory|Lymphoid / Disease state, Lineage and Cell class

TNIK PHTF2 HERC2P3 ZC3H7A TULP4

3.21e-0419113853ae18bc4e3dff49b5d5958da8ebc3f747274b69c
ToppCellControl-Epithelial-Ciliated_cells|Control / Condition, Lineage and Cell class

MAP6 DNAH2 SLC13A3 DNAH7 AHNAK2

3.21e-041911385ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

COL11A1 MXRA5 FGFRL1 SERTAD4 TRPV4

3.21e-041911385273c4a757292a9301de0eaeacdec91c9866be229
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

COL11A1 MXRA5 ASH1L RIF1 DST

1.71e-0550705GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CAF_4
Drugcolchicine; Down 200; 1uM; SKMEL5; HG-U133A

ENOSF1 ASH1L ZZEF1 VCAN CPSF1 ZC3H7B AHNAK2 BAHCC1

2.44e-051951378630_DN
DrugGanciclovir [82410-32-0]; Down 200; 15.6uM; HL60; HT_HG-U133A

GRK4 PHTF2 CBLIF TLK1 RECQL5 ASPSCR1 TMCO3 ZC3H7B

2.63e-0519713783030_DN
DrugEpirizole [18694-40-1]; Down 200; 17uM; MCF7; HT_HG-U133A

PDS5B KDM4C ZNF184 GON4L LIG3 RIF1 NFATC2IP SEMA3B

2.93e-0520013781681_DN
DrugNSC-107146

DHFR DHFR2

3.59e-0521372CID000267616
Druggamma-tBAMT

DHFR DHFR2

3.59e-0521372CID000125341
Drugaditoprim

DHFR DHFR2

3.59e-0521372CID000068755
Drug2,4-diamino-5-benzylpyrimidine

DHFR DHFR2

3.59e-0521372CID000081752
Drugmethotrexate-alpha-aspartate

DHFR DHFR2

3.59e-0521372CID000100376
Drugethyl isocyanatoacetate

DHFR DHFR2

3.59e-0521372CID000076283
Drug3'-fluoroaminopterin

DHFR DHFR2

3.59e-0521372CID000128780
DrugDIVEMA-MTX

DHFR DHFR2

3.59e-0521372CID000430857
Drug4-ethylacetophenone

DHFR DHFR2

3.59e-0521372CID000013642
Drug2,4-diamino-5-phenylpyrimidine

DHFR DHFR2

3.59e-0521372CID000134761
DrugAC1O3EGO

ENOSF1 SALL1

3.59e-0521372CID006326449
Diseasesalivary gland cancer (implicated_via_orthology)

GON4L YY1AP1

2.17e-0521382DOID:8850 (implicated_via_orthology)
DiseaseJoubert syndrome 4 (is_implicated_in)

NPHP1 NPHP4

6.49e-0531382DOID:0110999 (is_implicated_in)
DiseaseR-6-hydroxywarfarin measurement

CDS2 DNAH2 FGFRL1 SLC28A3 SEMA6D

2.03e-041141385EFO_0803327
DiseaseHbA1c measurement, polycystic ovary syndrome

CUX2 LMOD2

2.15e-0451382EFO_0000660, EFO_0004541
Diseasecancer (implicated_via_orthology)

CDS1 CUX2 CDS2 DST DHFR DHFR2 CUX1

2.78e-042681387DOID:162 (implicated_via_orthology)
Diseasenephronophthisis (is_implicated_in)

NPHP1 NPHP4

3.22e-0461382DOID:12712 (is_implicated_in)
Diseaseserum gamma-glutamyl transferase measurement

TNIK CUX2 SRARP ASH1L GON4L CCDC50 SLC28A3 SALL1 SEMA6D KDM2B YY1AP1 ARAP2 BAHCC1

3.72e-0491413813EFO_0004532
DiseaseNephronophthisis, familial juvenile

NPHP1 NPHP4

4.49e-0471382C1855681
DiseaseSenior-Loken syndrome (is_implicated_in)

NPHP1 NPHP4

4.49e-0471382DOID:0050576 (is_implicated_in)
DiseaseRenal dysplasia and retinal aplasia

NPHP1 NPHP4

4.49e-0471382cv:C0403553
Diseasevitamin k-dependent protein S measurement

AKNA DHFR2

4.49e-0471382EFO_0020850
DiseaseDisorder of eye

NPHP1 COL11A1 NPHP4 FAM161A VCAN CPLANE1

5.01e-042121386C0015397
Diseaseserum metabolite measurement

TNIK ENOSF1 KDM4C SLC28A3 SLC13A3 TLK1 IGF2R SALL1 DNAH17 PAH NCOA7 LOXL4 PPP6R3

5.08e-0494513813EFO_0005653
DiseaseNephronophthisis

NPHP1 NPHP4

7.65e-0491382cv:C0687120
Diseasenephronophthisis (implicated_via_orthology)

NPHP1 NPHP4

7.65e-0491382DOID:12712 (implicated_via_orthology)
Diseasecarpal tunnel syndrome

COL11A1 SNAP47 MTMR11 VCAN

8.22e-04891384EFO_0004143
Diseasegastric carcinoma

CUX2 ASH1L PGBD1 GON4L

8.22e-04891384EFO_0000178
Diseasesubiculum volume

TNIK SEMA6D VCAN

1.08e-03431383EFO_0009399
Diseaseblood phosphate measurement

EPS15 CUX2 RAD51AP1 EIF4G3 CUX1

1.39e-031741385EFO_0010972
DiseaseRenal dysplasia and retinal aplasia (disorder)

NPHP1 NPHP4

1.39e-03121382C0403553
DiseaseADHD symptom measurement

LMOD2 CUX1

1.39e-03121382EFO_0007860
Diseasehematologic cancer (implicated_via_orthology)

CUX2 CUX1

1.64e-03131382DOID:2531 (implicated_via_orthology)
DiseaseNephronophthisis

NPHP1 NPHP4

1.64e-03131382C0687120
DiseaseCiliopathies

NPHP1 EVC2 NPHP4 CPLANE1

1.80e-031101384C4277690
Diseasewaist-hip ratio

CUX2 COL11A1 PHTF2 SLC28A3 SLC13A3 ZZEF1 ONECUT1 TSEN2 NOSIP NEDD9 DNAH17 SEMA3B ASPSCR1 CUX1

1.86e-03122613814EFO_0004343
DiseasePolydactyly

EVC2 C2CD3 SALL1 CPLANE1

2.26e-031171384C0152427
Diseasegout

CUX2 SLC28A3 SLC13A3 DST PIBF1

2.33e-031961385EFO_0004274
DiseaseSpondyloepiphyseal Dysplasia

COL11A1 TRPV4

2.50e-03161382C0038015
DiseaseSpondyloepiphyseal Dysplasia Tarda, X-Linked

COL11A1 TRPV4

2.50e-03161382C3541456
DiseaseSchwartz-Jampel Syndrome, Type 1

COL11A1 TRPV4

2.50e-03161382C4551479
DiseaseSchwartz-Jampel Syndrome

COL11A1 TRPV4

2.50e-03161382C0036391
DiseaseMelnick-Needles Syndrome

COL11A1 TRPV4

2.50e-03161382C0025237
Diseasetestosterone measurement

CUX2 DNAH2 AKNA FGFRL1 SLC28A3 VARS2 ONECUT1 NEDD9 ZC3H7A SEMA6D FAM186A NYNRIN YY1AP1 MME

2.66e-03127513814EFO_0004908
DiseaseVan Buchem disease

COL11A1 TRPV4

2.82e-03171382C0432272
DiseaseCharcot-Marie-Tooth disease type 2

TRPV4 MME

2.82e-03171382cv:C0270914
DiseaseCongenital hernia of foramen of Morgagni

FGFRL1 IGF2R

3.52e-03191382C0265699
DiseaseCongenital hernia of foramen of Bochdalek

FGFRL1 IGF2R

3.52e-03191382C0265700
DiseaseOsteochondrodysplasias

COL11A1 TRPV4

3.52e-03191382C0029422
DiseaseDyschondroplasias

COL11A1 TRPV4

3.52e-03191382C0013366
Diseasecomparative body size at age 10, self-reported

KDM4C ZNF184 LRRC37A2 MTMR11 SEMA6D ZC3H7B PPP6R3

3.70e-034201387EFO_0009819
Diseasereaction time measurement

TNIK CUX2 ZNF184 LRRC37A2 SLC28A3 CCDC88B SEMA6D DHFR EIF4G3

3.88e-036581389EFO_0008393
DiseaseMultiple Epiphyseal Dysplasia

COL11A1 TRPV4

3.90e-03201382C0026760
DiseaseFamilial aplasia of the vermis

NPHP1 CPLANE1

3.90e-03201382cv:C0431399
DiseaseCongenital diaphragmatic hernia

FGFRL1 IGF2R

4.30e-03211382C0235833
DiseaseHIV-1 infection, Susceptibility to viral and mycobacterial infections

KDM4C NEDD9

4.30e-03211382EFO_0000180, Orphanet_391311
DiseaseJoubert syndrome 1

PIBF1 CPLANE1

4.30e-03211382C4551568
DiseaseC-reactive protein measurement

CUX2 CCDC168 ZZEF1 ONECUT1 TLK1 SALL1 NYNRIN DNAH17 RNF10 KDM2B EIF4G3 CUX1 FAM177A1

4.39e-03120613813EFO_0004458
Diseasemean reticulocyte volume

PDS5B KDM4C MBD1 DNAH2 CHTF18 NYNRIN C1orf105 HELZ2 TMCO3 BORA

4.43e-0379913810EFO_0010701
DiseaseMalignant neoplasm of breast

CDS1 COL11A1 SRARP LRRC37A2 KCNIP3 RIF1 LRRC37A DHFR ANKRD30A MME HERC2 CUX1

4.65e-03107413812C0006142

Protein segments in the cluster

PeptideGeneStartEntry
PARVSKEATAPGKWK

CHTF18

331

Q8WVB6
STKKAEPPTWAQLKK

ERVK-25

41

P61579
ILQRKDTWTPKTKPV

BAHCC1

1411

Q9P281
SWKSERSKPPLKDLG

ASH1L

2841

Q9NR48
TAQPVKRSLGKVPKW

ASPSCR1

531

Q9BZE9
STKKAEPPTWAQLKK

ERVK-19

41

O71037
STKKAEPPTWAQLKK

ERVK-8

41

Q902F8
STKKAEPPTWAQLKK

ERVK-9

41

Q9UKH3
RPTKETSEKFSWPAK

ANKRD30B

341

Q9BXX2
TPLIKLSPKKTWEGF

CDS1

266

Q92903
PLPRTKKGSWLADKV

CCDC88B

1306

A6NC98
TKLPTPTGSTKKPWD

VCAN

421

P13611
ITKPVENDISKWKPS

NEDD9

676

Q14511
SSLDKRKQDPEWKPK

CCDC50

226

Q8IVM0
RKQDPEWKPKTAKAA

CCDC50

231

Q8IVM0
ARPKPWNKLTVRGKE

CUX1

591

P39880
KPWSKLTQKGREPFI

CUX1

986

P39880
KGRPRKIAWEKKETP

ANKRD30A

411

Q9BXX3
FGRTPLIKLSPKKTW

CDS2

246

O95674
PEWVTAKPVKKNVLT

ALDH3A2

76

P51648
IWPPAGKERKRSITK

ARAP2

1541

Q8WZ64
WDVGKITPQKLPSLK

AP3M1

341

Q9Y2T2
SRPKPWSKLTQKGRE

CUX2

936

O14529
EIRSPSAESKKPKWV

RAD51AP1

291

Q96B01
STKKAEPPTWAQLKK

HERVK_113

41

P61574
STKKAEPPTWAQLKK

ERVK-19

41

P61572
TKKAEPPTWAQLKKL

ERVK-21

41

P61571
STKKAEPPTWAQLKK

ERVK-6

41

Q69383
STKKAEPPTWAQLKK

ERVK-9

41

P61573
DRLPGKKTTKLWVPD

PDS5B

801

Q9NTI5
KKTTKLWVPDEEVSP

PDS5B

806

Q9NTI5
AKDWKTKGSPRTSPK

EDC4

906

Q6P2E9
QKKQRTIPWRSKSPE

IQCC

426

Q4KMZ1
RTWKCISKPSEFPIK

KCTD19

131

Q17RG1
PPKRAGTLKDWSKQR

KCTD19

721

Q17RG1
PSKDKDKVLPSFWIP

NOSIP

151

Q9Y314
SWPEGAKKVRLVPKE

FHIP1B

641

Q8N612
SPKKLKKDPAQRWSL

LRRC37A3

146

O60309
KTKPQRKGSWAEEPR

LOXL4

296

Q96JB6
PRSHWKKTPVVLKAT

ENTPD5

116

O75356
RAWTDIKPVKPIKAK

MAP6

306

Q96JE9
SPKKLKKDPAQRWSL

LRRC37A2

146

A6NM11
SPKKLKKDPAQRWSL

LRRC37A

146

A6NMS7
KKDVLPTVDPTKLTW

FAM177A1

81

Q8N128
KKILVSWSSPKPIGP

ERVS71-1

226

P61550
KWTPRISPEDHSKKR

MTMR11

671

A4FU01
KWKSSGISLPPVDKK

HERC2

166

O95714
DLKPWEKSPILKISA

IBTK

1076

Q9P2D0
SWIKETTKKVPIVQP

DST

4386

Q03001
SPWSSPKLPKKVQTV

LMOD2

396

Q6P5Q4
EPPSKKKRVDATAGW

CPSF1

416

Q10570
PDKKSEGVRISSWPK

COL11A1

1651

P12107
KLAKFKPLWIEEPTS

ENOSF1

266

Q7L5Y1
DTAVWLPRSKDLKKP

MBD1

586

Q9UIS9
LTRPEAAEPRKKKWT

FGFRL1

191

Q8N441
SPKTESNKEIPWTLK

CSNKA2IP

401

A0A1B0GTH6
LRNPKPWSKLKSGRE

ONECUT1

331

Q9UBC0
TDINTPKPKKKQRWT

MME

11

P08473
PKPKKKQRWTPLEIS

MME

16

P08473
KPEKSDPSELSWPKS

KDM4C

496

Q9H3R0
IPSWPKKNLFKRESP

EVC2

131

Q86UK5
VKPVTISRAWKKILP

JRKL

376

Q9Y4A0
SKDPSKIPSWLKVNK

LIG3

751

P49916
KKWRHKSSAPKRSIP

IRS1

51

P35568
PPKWKAPRVLSFSLK

OAS2

456

P29728
RDKKKDTVPWFPRTI

PAH

111

P00439
FGRTWKTTVKPTKRP

NPHP4

71

O75161
RRKWEEKIPNPSKSH

CSF2RB

471

P32927
TPEPSKKEWNCKKTT

CBLIF

236

P27352
TWPKKTPKNRAVGRP

KDM2B

571

Q8NHM5
AFWTPLKKPKESVNK

C2CD3

1446

Q4AC94
SPKQKTTFSKWVRPE

CAPN7

251

Q9Y6W3
EILTSTGIKQKKPWP

CPLANE1

6

Q9H799
PDTKKFLPWTDKVPS

DNAH17

2401

Q9UFH2
STKKAEPPTWAQLKK

ERVK-25

41

P61570
STKKAEPPTWAQLKK

ERVK-6

41

Q69384
KQVKPKAWLSRGPSP

CD1D

201

P15813
SRPKWKPKAKVPLQT

DHX57

86

Q6P158
KSTKLPTPGKFRWSI

BORA

46

Q6PGQ7
KTWFSIPEKNRPLKG

DHFR

56

P00374
WESKSKPTTLKPIIL

DNAH7

451

Q8WXX0
SKSKKEIFRWPESPK

IGHD

91

P01880
KGVVIPTWNISPIKK

GON4L

336

Q3T8J9
IWKQTKTSPKPLPSR

AKNA

296

Q7Z591
RFKGTTKPVNWLKPV

TMEM30A

226

Q9NV96
TKKAEPPTWAQLKKL

ERVK-21

41

P61565
AKKSPLSWDTKSEPR

MARCHF10

396

Q8NA82
AKVPKKAKTWIPEVH

DDX24

171

Q9GZR7
KTWFSIPEKNRPLKD

DHFR2

56

Q86XF0
SSKKTKCIKRRPPWQ

CEP57L1

246

Q8IYX8
STKKAEPPTWAQLKK

HERVK_113

41

Q902F9
PPSKRKTWVVSPAEK

EPS15

211

P42566
FWKKPTLPEKGSSDV

CCDC168

61

Q8NDH2
PWILSSVSDTKKPKV

FAM186A

2076

A6NE01
RKKRKEWVPTITVPE

FAM161A

226

Q3B820
KSKLKTWQGLRRPPS

HELZ2

2441

Q9BYK8
RSKKWKEILTLPPVS

GRK4

26

P32298
HTPLSKKEGIKWQRP

KCNIP3

21

Q9Y2W7
PKIRSWTSFEDKLPK

DNAH2

2361

Q9P225
KAPNTETEPLLTWKK

SLC13A3

406

Q8WWT9
KPVTSWLDTKPVLPT

SALL1

536

Q9NSC2
IAITVPKTWKKPKDR

EIF4G3

501

O43432
PKTWKKPKDRTRTTE

EIF4G3

506

O43432
WPPRDEGLKAKTKSR

PRRT3

181

Q5FWE3
RPPLAKRDSKTNIWK

FAM171B

801

Q6P995
IHTVRATWQPKKPKT

NPHP1

421

O15259
KKPKTWTFSPQVTRI

NPHP1

431

O15259
KGDKKPRVWVVPTQL

NYNRIN

1526

Q9P2P1
RWKPFEIPKASQKKV

HGD

96

Q93099
SLWTKSSKEESLPKP

APOOL

181

Q6UXV4
RNPKPWSKLKSGRET

ONECUT3

361

O60422
LKNWKPARPVGIEKS

IGF2R

996

P11717
SKSPAESIKAWRPKE

VARS2

66

Q5ST30
PSFTISDPKLVAKWK

TSEN2

76

Q8NCE0
DVASSSWPVILKPKK

STAP2

326

Q9UGK3
KAKPESPWTSLTRKG

PHTF2

101

Q8N3S3
KGKPVKAAPVRSSTW

SRARP

136

Q8NEQ6
GKLALTKFPKSPETW

PTAR1

126

Q7Z6K3
PEKLRKVWKISLQGP

TMCO3

341

Q6UWJ1
SKLWKTPPETKPRED

SNAP47

226

Q5SQN1
TWVKKGEPLPVKLNS

NCOA7

581

Q8NI08
KSPQRPSDWSKKKNE

RIF1

781

Q5UIP0
RWEKPSPSNVTERKK

SGO2

261

Q562F6
QIWNPDSKKTKKRPP

CCT8L1P

531

A6NM43
LFWPETEKPKITLKN

SLC28A3

406

Q9HAS3
KRPIAIKSPKDKWQP

HERC2P3

321

Q9BVR0
IKSPKDKWQPLLSTV

HERC2P3

326

Q9BVR0
PEKSWTKRDIKPNFP

PGBD1

386

Q96JS3
SWKKSLRKKEASPPS

SERTAD4

331

Q9NUC0
QKPLPFDRDTKTLWK

MROH2B

1091

Q7Z745
PGSPWKTKLRTKDKE

NFATC2IP

171

Q8NCF5
WEVPKDRVKPKRTAS

OSBPL10

491

Q9BXB5
SRSWDSLPPSKRKKA

BRMS1

191

Q9HCU9
PKIKLPSFRWSPKKE

AHNAK2

4956

Q8IVF2
PSFRWSPKKETGPKV

AHNAK2

4961

Q8IVF2
LKASVPKFDKIPWLS

C1orf105

6

O95561
EVQPTPAKDTWKGKR

RECQL5

841

O94762
SWKGRVPKSEKEKPV

TULP4

21

Q9NRJ4
KEPPKISNKVDVWSV

TLK1

646

Q9UKI8
PRNPAPRLKSKKWSK

TNIK

246

Q9UKE5
QETHPKKPWQKVTVR

ZNF691

81

Q5VV52
DNISKRAKKLAWPAP

SEMA3B

81

Q13214
WPKTAPKKDENSLVP

RNF10

726

Q8N5U6
PWTNIDLKEAKKVPS

TECPR1

486

Q7Z6L1
KPAAVLKPSDWEKSS

XRN2

776

Q9H0D6
PKPTLFTKKEAPEWS

PIBF1

736

Q8WXW3
DTWEPPRHVKRKLSK

ZHX1

856

Q9UKY1
ARGEKKPRWVKIFTP

SNX27

491

Q96L92
STKKAEPPTWAQLKK

ERVK-8

41

P61575
KKPLPSGPKSDVWSL

TBCK

176

Q8TEA7
VVEVRSKPKSKWRPQ

TOP3A

311

Q13472
SKPKSKWRPQALDTV

TOP3A

316

Q13472
PKKAWRQKRSSVLKP

YY1AP1

446

Q9H869
NVEDKSWKKIRPRPT

ZC3H7A

481

Q8IWR0
TDKWPKKVTFKAGPR

ZZEF1

1156

O43149
KPPSWKVPDQFLDSK

VSIG10L

56

Q86VR7
PKTEVIPNKKLTWRS

SEMA6D

86

Q8NFY4
LEPPKKSVMKTTWGV

PPP6R3

321

Q5H9R7
LSKPKKQWGTPDRKL

THEGL

186

P0DJG4
KRWRKKIIEKQPQSP

TRPV4

121

Q9HBA0
PKEIKVTEKTIPSWE

ZNF184

161

Q99676
KAKRKWVSVRPLPSI

ZC3H7B

736

Q9UGR2
EATGKPKPFVTWTKV

MXRA5

1876

Q9NR99
KTSLPWVPPDTKLSK

MSC

131

O60682
EPPTWLELQAVKSKK

MYO7B

1181

Q6PIF6