Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-18 ERVK-7 ERVK-21 ERVK-9

6.23e-0637654GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-18 ERVK-7 ERVK-21 ERVK-9

6.94e-0638654GO:0070001
DomainZINC_FINGER_C2H2_2

ZNF462 ZSCAN5B ZNF460 ZNF728 ZNF335 ZNF790 HELZ2 AEBP2 ZNF208 ZNF518B ZNF518A

5.01e-057756311PS50157
DomainZINC_FINGER_C2H2_1

ZNF462 ZSCAN5B ZNF460 ZNF728 ZNF335 ZNF790 HELZ2 AEBP2 ZNF208 ZNF518B ZNF518A

5.13e-057776311PS00028
DomainZnf_C2H2-like

ZNF462 ZSCAN5B ZNF460 ZNF728 ZNF335 ZNF790 HELZ2 AEBP2 ZNF208 ZNF518B ZNF518A

6.37e-057966311IPR015880
DomainC2H2_Znf_fam

ZSCAN5B ZNF518B ZNF518A

7.04e-0524633IPR027775
DomainZnF_C2H2

ZNF462 ZSCAN5B ZNF460 ZNF728 ZNF335 ZNF790 HELZ2 AEBP2 ZNF208 ZNF518B ZNF518A

7.29e-058086311SM00355
DomainZnf_C2H2/integrase_DNA-bd

ZNF462 ZSCAN5B ZNF460 ZNF728 ZNF335 ZNF790 AEBP2 ZNF208 ZNF518B ZNF518A

1.01e-046946310IPR013087
DomainLipase_GDSL

PLB1 PAFAH1B3

1.11e-045632PF00657
DomainLIPASE_GDSL_SER

PLB1 PAFAH1B3

1.11e-045632PS01098
DomainGDSL

PLB1 PAFAH1B3

1.11e-045632IPR001087
Domain-

PLB1 PAFAH1B3

2.33e-0476323.40.50.1110
DomainSGNH_hydro

PLB1 PAFAH1B3

3.09e-048632IPR013830
DomainZnf_C2H2

ZNF462 ZSCAN5B ZNF460 ZNF728 ZNF335 ZNF790 AEBP2 ZNF208 ZNF518B ZNF518A

3.37e-048056310IPR007087
DomainNPIP

NPIPB8 NPIPB6

9.93e-0414632IPR009443
Domain-

ZNF462 ZSCAN5B ZNF460 ZNF728 ZNF335 ZNF790 AEBP2 ZNF208

1.94e-036796383.30.160.60
Domainzf-C2H2

ZNF462 ZSCAN5B ZNF460 ZNF728 ZNF335 ZNF790 ZNF208 ZNF518A

2.21e-03693638PF00096
PathwayWP_INTERACTIONS_OF_NATURAL_KILLER_CELLS_IN_PANCREATIC_CANCER

KLRK1 PVR NCR1

7.65e-0528423M42549
Pubmed

Quantitation of HERV-K env gene expression and splicing in human breast cancer.

ERVK-18 ERVK-7 ERVK-21

7.13e-08568312629516
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

ZNF462 METTL13 MYCBP2 SYNE2 HELZ2 DIP2C ZNF518A

3.00e-0722568712168954
Pubmed

The DNA sequence and biology of human chromosome 19.

ZSCAN5B TMEM221 PVR PAFAH1B3 SAFB2 ZNF208 TJP3

1.42e-0628468715057824
Pubmed

HLA class I, NKG2D, and natural cytotoxicity receptors regulate multiple myeloma cell recognition by natural killer cells.

KLRK1 NCR1

3.77e-06268215328155
Pubmed

Pathological phosphorylation of tau and TDP-43 by TTBK1 and TTBK2 drives neurodegeneration.

TTBK2 TTBK1

3.77e-06268229409526
Pubmed

Lysis of HIV-1-infected autologous CD4+ primary T cells by interferon-alpha-activated NK cells requires NKp46 and NKG2D.

KLRK1 NCR1

3.77e-06268226372382
Pubmed

Mechanisms of Regulation and Diverse Activities of Tau-Tubulin Kinase (TTBK) Isoforms.

TTBK2 TTBK1

3.77e-06268232424773
Pubmed

Human NK cells kill resting but not activated microglia via NKG2D- and NKp46-mediated recognition.

KLRK1 NCR1

3.77e-06268218941207
Pubmed

Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis.

TTBK2 TTBK1

3.77e-06268237059819
Pubmed

Tumour-experienced T cells promote NK cell activity through trogocytosis of NKG2D and NKp46 ligands.

KLRK1 NCR1

3.77e-06268219498463
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ZNF462 METTL13 TTBK1 HELZ2 SAFB2 DIP2C ZNF518B TRAPPC9

5.40e-0649368815368895
Pubmed

Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.

ERVK-18 ERVK-21 ERVK-9

5.71e-061868318664271
Pubmed

Functional Proteomic Analysis of Repressive Histone Methyltransferase Complexes Reveals ZNF518B as a G9A Regulator.

ZNF462 AEBP2 ZNF518B ZNF518A

7.30e-066368425680957
Pubmed

Binary outcomes of enhancer activity underlie stable random monoallelic expression.

KLRK1 NCR1

1.13e-05368235617021
Pubmed

Decreased NKp46 and NKG2D and elevated PD-1 are associated with altered NK-cell function in pediatric transplant patients with PTLD.

KLRK1 NCR1

1.13e-05368222105417
Pubmed

Tau-tubulin kinase 1 (TTBK1), a neuron-specific tau kinase candidate, is involved in tau phosphorylation and aggregation.

TTBK2 TTBK1

1.13e-05368216923168
Pubmed

Changes in natural killer cell subsets in pediatric liver transplant recipients.

KLRK1 NCR1

1.13e-05368222360401
Pubmed

Characterization of a novel NKG2D and NKp46 double-mutant mouse reveals subtle variations in the NK cell repertoire.

KLRK1 NCR1

1.13e-05368223649470
Pubmed

The immunoreceptor NKG2D promotes tumour growth in a model of hepatocellular carcinoma.

KLRK1 NCR1

1.13e-05368228128200
Pubmed

The requirement for DNAM-1, NKG2D, and NKp46 in the natural killer cell-mediated killing of myeloma cells.

KLRK1 NCR1

1.13e-05368217875681
Pubmed

The tau tubulin kinases TTBK1/2 promote accumulation of pathological TDP-43.

TTBK2 TTBK1

1.13e-05368225473830
Pubmed

Mutant KRAS Promotes NKG2D+ T Cell Infiltration and CD155 Dependent Immune Evasion.

KLRK1 PVR

1.13e-05368232727790
Pubmed

Human congenital infection with Trypanosoma cruzi induces phenotypic and functional modifications of cord blood NK cells.

KLRK1 NCR1

1.13e-05368216690951
Pubmed

Analysis of the Expression of Surface Receptors on NK Cells and NKG2D on Immunocytes in Peripheral Blood of Patients with Nasopharyngeal Carcinoma.

KLRK1 NCR1

1.13e-05368229580037
Pubmed

Decreased expression of NKG2D, NKp46, DNAM-1 receptors, and intracellular perforin and STAT-1 effector molecules in NK cells and their dim and bright subsets in metastatic melanoma patients.

KLRK1 NCR1

2.25e-05468224769842
Pubmed

Altered NKp30, NKp46, NKG2D, and DNAM-1 Expression on Circulating NK Cells Is Associated with Tumor Progression in Human Gastric Cancer.

KLRK1 NCR1

2.25e-05468230255106
Pubmed

Effect of recombinant cytokines on the expression of natural killer cell receptors from patients with TB or/and HIV infection.

KLRK1 NCR1

2.25e-05468222715368
Pubmed

Cutting edge: tumor-targeting antibodies enhance NKG2D-mediated NK cell cytotoxicity by stabilizing NK cell-tumor cell interactions.

KLRK1 NCR1

2.25e-05468223183896
Pubmed

Ligands for natural killer cell-activating receptors are expressed upon the maturation of normal myelomonocytic cells but at low levels in acute myeloid leukemias.

KLRK1 NCR1

2.25e-05468215657183
Pubmed

Largely preserved functionality after the combined loss of NKG2D, NCR1 and CD16 demonstrates the remarkable plasticity of NK cell responsiveness.

KLRK1 NCR1

2.25e-05468237520575
Pubmed

Role of NKp46+ natural killer cells in house dust mite-driven asthma.

KLRK1 NCR1

2.25e-05468229444897
Pubmed

Up-regulation of NK cell activating receptors following allogeneic hematopoietic stem cell transplantation under a lymphodepleting reduced intensity regimen is associated with elevated IL-15 levels.

KLRK1 NCR1

2.25e-05468218275895
Pubmed

Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones.

PLB1 CYP17A1 LRP2

3.09e-053168315583024
Pubmed

A revised nomenclature for transcribed human endogenous retroviral loci.

ERVK-18 ERVK-7 ERVK-21 ERVK-9

3.57e-059468421542922
Pubmed

Contribution of NK cells to immunotherapy mediated by PD-1/PD-L1 blockade.

KLRK1 NCR1

3.75e-05568230198904
Pubmed

TLR9 Regulates the NF-κB-NLRP3-IL-1β Pathway Negatively in Salmonella-Induced NKG2D-Mediated Intestinal Inflammation.

KLRK1 TLR9

3.75e-05568228576980
Pubmed

Modulation of NKG2D, NKp46, and Ly49C/I facilitates natural killer cell-mediated control of lung cancer.

KLRK1 NCR1

3.75e-05568230381460
Pubmed

A High-Density Map for Navigating the Human Polycomb Complexome.

ZNF462 MYCBP2 ZNF460 AEBP2 ZNF518B MBD6 ZNF518A

5.20e-0549568727705803
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ANKS6 MYCBP2 ZNF335 HELZ2 DIP2C NLE1 MAPKBP1 MBD6 TRAPPC9 TJP3

5.50e-051105681035748872
Pubmed

CD155 on HIV-Infected Cells Is Not Modulated by HIV-1 Vpu and Nef but Synergizes with NKG2D Ligands to Trigger NK Cell Lysis of Autologous Primary HIV-Infected Cells.

KLRK1 PVR

5.62e-05668227296670
Pubmed

Balance between activating NKG2D, DNAM-1, NKp44 and NKp46 and inhibitory CD94/NKG2A receptors determine natural killer degranulation towards rheumatoid arthritis synovial fibroblasts.

KLRK1 NCR1

5.62e-05668224673109
Pubmed

NK1.1+ innate lymphoid cells in salivary glands inhibit establishment of tissue-resident memory CD8+ T cells in mice.

KLRK1 NCR1

5.62e-05668232734619
Pubmed

When killers become thieves: Trogocytosed PD-1 inhibits NK cells in cancer.

KLRK1 NCR1

7.86e-05768235417234
Pubmed

Migratory Dendritic Cells, Group 1 Innate Lymphoid Cells, and Inflammatory Monocytes Collaborate to Recruit NK Cells to the Virus-Infected Lymph Node.

TLR9 NCR1

1.05e-04868229972776
Pubmed

TTBK2 with EB1/3 regulates microtubule dynamics in migrating cells through KIF2A phosphorylation.

TTBK2 TTBK1

1.05e-04868226323690
Pubmed

DNAM-1 expression marks an alternative program of NK cell maturation.

PVR NCR1

1.68e-041068225818301
Pubmed

NK cell receptor NKG2D sets activation threshold for the NCR1 receptor early in NK cell development.

KLRK1 NCR1

1.68e-041068230224819
Pubmed

A forward genetic screen in mice identifies mutants with abnormal cortical patterning.

MYCBP2 LRP2

2.05e-041168223968836
Pubmed

POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.

SYNE2 EFCAB2 SAFB2 TLR9 SVOP

2.14e-0427768530745168
Pubmed

The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate Intraflagellar Transport at the Ciliary Base.

TTBK2 IFT57

2.45e-041268228625565
Pubmed

Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.

ERVK-21 ERVK-9

2.45e-041268214557543
Pubmed

Activity-dependent neuroprotective protein recruits HP1 and CHD4 to control lineage-specifying genes.

ZNF462 ZNF518B ZNF518A

4.20e-047468329795351
Pubmed

Control of Viral Infection by Natural Killer Cell Inhibitory Receptors.

KLRK1 NCR1

4.44e-041668232726632
Pubmed

Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation.

ZNF462 ZNF460 ZNF518A

5.87e-048368320562864
Pubmed

A novel miR1983-TLR7-IFNβ circuit licenses NK cells to kill glioma cells, and is under the control of galectin-1.

KLRK1 TLR9

6.30e-041968234249474
Pubmed

Nephronophthisis-Related Ciliopathies

ANKS6 MAPKBP1

7.72e-042168227336129
Pubmed

Characterization of 458 single nucleotide polymorphisms of disease candidate genes in the Korean population.

LRP2 HDC

8.48e-042268212768436
Pubmed

Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

TTBK2 METTL13 MYCBP2

1.01e-0310068310048485
Pubmed

Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

DLC1 HELZ2 ZNF518B

1.07e-0310268311214970
Pubmed

Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

ZNF462 TTBK1 DCAF5

1.23e-0310768311347906
Pubmed

Genetic link between renal birth defects and congenital heart disease.

ANKS6 LRP2

1.38e-032868227002738
Pubmed

CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation.

NLE1 WDR76

1.38e-032868217041588
Pubmed

Gene-smoking interactions identify several novel blood pressure loci in the Framingham Heart Study.

LRP2 TRAPPC9

1.80e-033268225189868
Pubmed

Analysis of mouse embryonic patterning and morphogenesis by forward genetics.

TTBK2 TBX6

1.91e-033368215755804
CytobandEnsembl 112 genes in cytogenetic band chr19q13

GPR4 ZSCAN5B CNFN ZNF460 PVR PAFAH1B3 ZNF790 NCR1

3.76e-041192688chr19q13
CytobandEnsembl 112 genes in cytogenetic band chr15q15

TTBK2 MAPKBP1 WDR76

1.38e-03147683chr15q15
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF462 ZSCAN5B ZNF460 ZNF728 ZNF335 ZNF790 ZNF208 ZNF518B ZNF518A

5.73e-0571845928
GeneFamilyMethyltransferase like

METTL13 NTMT2

3.05e-0333452963
GeneFamilyWD repeat domain containing

NLE1 MAPKBP1 WDR76 DCAF5

4.03e-03262454362
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype|TCGA-Lung / Sample_Type by Project: Shred V9

ARSL EFCAB2 XKRX ACOX2 TJP3

6.27e-06181645c783c2ecca7ab8e07646fa92dc7d436d24939d03
ToppCell368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DOCK4 ZNF460 ZNF335 HELZ2 MAPKBP1

7.16e-0618664577bebf576eb9b96ecb4fefb8a82a31aaaa917fc0
ToppCell368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DOCK4 ZNF460 ZNF335 HELZ2 MAPKBP1

7.16e-0618664513bc41c60fd628af31899a5e8b480e06cc4781be
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE2 LRP2 DIP2C TRAPPC9 SORCS1

8.35e-06192645e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellTracheal-10x5prime-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

GPR4 DLC1 ZNF208 ZNF518B WDR76

9.69e-06198645c77421898cc84ae2e8cc335087198dd05f13bfa5
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c02-NCAM1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ARSL ZNF208 NCR1 PCDH17

4.28e-05135644b444005987093efab3265201b3541d7941816cc2
ToppCellSevere-Myeloid-Mast-|Severe / Condition, Lineage, Cell class and cell subclass

ZNF462 DLC1 ENTHD1 HDC

5.66e-05145644ce307d45425a5191882078f049f85477eec40b69
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KLRK1 CYP17A1 GBGT1 NCR1

5.66e-0514564423a1ee986774725a9f5a9154fbbd023031fb0452
ToppCellSevere-Myeloid-Mast|Severe / Condition, Lineage, Cell class and cell subclass

ZNF462 DLC1 ENTHD1 HDC

5.66e-05145644e0bfd2ffdbd6c197ef0a04e983396ebd87ef7127
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Papillary_Adenocarcinoma|TCGA-Lung / Sample_Type by Project: Shred V9

ZNF728 ZNF208 ACOX2 TJP3

7.33e-0515564457259549d7ad97d9f628b821417be5ddac7dbff7
ToppCellfacs-Marrow-KLS-18m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRK1 TMEM221 TLR9 NCR1

7.70e-051576445d08ff0ba9d3df9cc30f13cab2d2b395ea6f3446
ToppCellfacs-Marrow-KLS-18m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLRK1 TMEM221 TLR9 NCR1

7.70e-05157644ad9c9b7dfeee3ae46e7e593c51a0407df12195b4
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KLRK1 NLE1 NCR1 WDR76

8.09e-0515964495128a2367ff2a639b21913c0350924c174faef8
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLB1 PAFAH1B3 LRP2 SORCS1

8.29e-05160644c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLB1 PAFAH1B3 LRP2 SORCS1

8.29e-0516064425c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCelldroplet-Lung-LUNG-1m-Myeloid-plasmacytoid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM221 PAFAH1B3 TLR9 XKRX

9.56e-051666446e6075d0c913e2516083f6dcab21d5878bcef7a4
ToppCelldroplet-Lung-1m-Hematologic-myeloid-plasmacytoid_dendritic_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMEM221 PAFAH1B3 TLR9 XKRX

9.56e-051666441ca888ae8168707493f19ee52a89d7c70e6cb51d
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Plasmacytoid_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM221 PAFAH1B3 TLR9 XKRX

9.56e-051666444fbe44e0aea197893614cd55f83119aa0f73ee53
ToppCellLPS-antiTNF-Endothelial-Mes-Like-Alv_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

METTL13 ZNF518B ACOX2 TBX6

9.56e-0516664494a00edf66d54bc5f7343daea700ca26cf38fd90
ToppCelldroplet-Lung-1m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMEM221 PAFAH1B3 TLR9 XKRX

9.56e-051666444cba4ca1aa2321b9ef7cd230932b890d2434a252
ToppCelldroplet-Liver-LIVER-30m-Myeloid-plasmacytoid_dendritic_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM221 C17orf99 PAFAH1B3 XKRX

1.10e-0417264424ecfda5e43e28f190089770cd2eae5bf2ed292b
ToppCelldroplet-Liver-LIVER-30m-Myeloid-plasmacytoid_dendritic_cells|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM221 C17orf99 PAFAH1B3 XKRX

1.10e-04172644db5a31cafce4346fe459d7f35210823fd7004439
ToppCell10x5'-GI_small-bowel-Mast|GI_small-bowel / Manually curated celltypes from each tissue

ZNF462 DLC1 ENTHD1 HDC

1.15e-04174644e94c980b25edfd0e8598c416828801fcc00e8ead
ToppCell10x5'-GI_small-bowel-Mast-Mast_cells|GI_small-bowel / Manually curated celltypes from each tissue

ZNF462 DLC1 ENTHD1 HDC

1.15e-0417464405525bf0a2bde2be4f7c147b17a24530ce8819e0
ToppCellsevere_COVID-19-HSPC|severe_COVID-19 / disease group, cell group and cell class (v2)

ZNF462 ARSL PCDH17 HDC

1.15e-041746446d35bacf073537b272ff821e604c899fb9ce6a7c
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Endothelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR4 C17orf99 GBGT1 PCDH17

1.17e-04175644c36b4526970db9ccfbe2c70b00961fab9f13b133
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR4 C17orf99 GBGT1 PCDH17

1.17e-04175644c1e082538f31b5c98ac63f71dcca4a1211a14708
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Endothelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR4 C17orf99 GBGT1 PCDH17

1.17e-041756442f9b5bdf8a62e8e99d1c4f677a8e5525bfd3b4ce
ToppCellfacs-Aorta|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR4 TMEM132D LRP2 PCDH17

1.20e-041766440b3491451be02c18a16cdb875645be47eb867a7f
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2-Slc17a8.Synpr-Sncg-Yjefn3_(Neuron.Gad1Gad2-Slc17a8.Synpr-Sncg-Yjefn3)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

GABRR1 LOXHD1 ACOX2

1.23e-0467643e53dfc288c943656a0b064afe593ea2101d75437
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2-Slc17a8.Synpr-Sncg-Yjefn3_(Neuron.Gad1Gad2-Slc17a8.Synpr-Sncg-Yjefn3)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

GABRR1 LOXHD1 ACOX2

1.23e-04676431841cee311a4b1b802c9e872793435afb730592f
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR4 TMEM221 PAFAH1B3 XKRX

1.31e-0418064464f01494a4052186773720e10b4e7c724ff94547
ToppCellcritical-Myeloid-Mast_cell|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ZNF462 DLC1 DIP2C HDC

1.33e-04181644f0d81ae74d3f32979624a94b2ef93774831a7970
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR4 TMEM221 PAFAH1B3 XKRX

1.36e-0418264433afbb7c4352b03266501b1f4f0e751c12c7350d
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

DOCK4 MYCBP2 ZNF728 ZNF518B

1.42e-0418464467164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell356C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|356C / Donor, Lineage, Cell class and subclass (all cells)

DOCK4 GPR4 LOXHD1 PCDH17

1.48e-04186644f0b78c7ee20279970ea8961bf59acb5262f2dce5
ToppCelldroplet-Tongue-nan-24m-Epithelial-suprabasal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPEB2 DLC1 CNFN SYNE2

1.48e-041866442913b5fd0617d024d600ba7015ec7b1961dade83
ToppCell356C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|356C / Donor, Lineage, Cell class and subclass (all cells)

DOCK4 GPR4 LOXHD1 PCDH17

1.48e-041866442b3c814a7dee8286ea113c63dc3de5daf0257d37
ToppCellwk_08-11-Epithelial-Distal_epithelial-epi-tip_early|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ARSL CNFN PAFAH1B3 HDC

1.51e-041876445f9696097741b6e2b7b410c15c6b5ed883ed5eb2
ToppCell10x5'-Lung-Mast|Lung / Manually curated celltypes from each tissue

ZNF462 DLC1 DIP2C HDC

1.51e-04187644f8ac5ca5cbe9c6f3d8c0fffc20fe08ca1aea43c0
ToppCell10x5'-Lung-Mast-Mast_cells|Lung / Manually curated celltypes from each tissue

ZNF462 DLC1 DIP2C HDC

1.51e-04187644da275d2c774b3e6a8ed77f777dd0676ecf2ddd2c
ToppCellwk_08-11-Epithelial-Distal_epithelial|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ARSL CNFN PAFAH1B3 HDC

1.51e-04187644eefffc2c6f7fa708a96e6bf07c6ce4e6c2e90847
ToppCelldroplet-Mammary_Gland-nan-3m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR4 DLC1 PCDH17 HDC

1.57e-0418964425781edbd08c6e413740b796ecc8ba1934bd3aa5
ToppCellcontrol-Myeloid-Mast_cell|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ZNF462 TTBK2 DLC1 HDC

1.64e-04191644afebdc59a1f884ce3f2f5fe040e16b0e95e4e7c5
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF462 DLC1 PCDH17 HDC

1.71e-04193644826b8dd801298b3e0cd76232feae5a14026b8806
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF462 DLC1 PCDH17 HDC

1.71e-0419364487d3a577d37fb0cb4b6313c596310de452bc3872
ToppCelldroplet-Tongue-nan-3m-Epithelial-suprabasal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPEB2 DLC1 CNFN SYNE2

1.71e-04193644a7002acf3be76b2cc6fc9364176f6b0d3bd27d9c
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PLB1 SYNE2 PVR TJP3

1.84e-04197644b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCell5'-Adult-Appendix-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK4 GPR4 SYNE2 PCDH17

1.84e-04197644e8e879b7634a29569061d3515d180784094a31e7
ToppCellwk_08-11-Epithelial-PNS|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PRSS56 SVOP PCDH17 SORCS1

1.84e-04197644ce3f9feb6935f0e9daf13673b0a0d6e92817e187
ToppCellTracheal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_pulmonary_venous|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

GPR4 ZSCAN5B DLC1 PCDH17

1.88e-041986446fd984da5d2c419aeb34c8cbd8a00440e2f820a5
ToppCellASK452-Endothelial|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

GPR4 DLC1 SYNE2 PCDH17

1.92e-041996440bc97a9a78aaafd1554ae6a61356ed9ea4983fa5
ToppCellLPS_IL1RA-Endothelial-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DLC1 SYNE2 ZNF518B PCDH17

1.95e-0420064472ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DLC1 SYNE2 ZNF518B PCDH17

1.95e-04200644dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellLPS_IL1RA-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DLC1 SYNE2 ZNF518B PCDH17

1.95e-042006445c092b2ecc081b5d04476c56333c338cd89ab984
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Gen_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

DLC1 SYNE2 ZNF518B PCDH17

1.95e-04200644a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCellSepsis-Bac-SEP-Myeloid-cDC1|Bac-SEP / Disease, condition lineage and cell class

ZNF462 ANKS6 CNFN PAFAH1B3

1.95e-04200644cd381644fd8b8674a017d267bfbb00f2668294ae
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

GPR4 DLC1 SYNE2 PCDH17

1.95e-042006443585484c7e24e941708bee471ca607d8ccee74e6
ToppCellSepsis-Leuk-UTI-Lymphocyte-T/NK-MAIT|Leuk-UTI / Disease, condition lineage and cell class

ANKS6 ZNF460 MAPKBP1 TJP3

1.95e-042006447e0d0f051c197c2c70080f039e1c4dd68db8e74f
Diseaselymphoproliferative syndrome (is_marker_for)

KLRK1 NCR1

1.22e-053602DOID:0060704 (is_marker_for)
Diseaseanogenital venereal wart (is_marker_for)

KLRK1 TLR9 NCR1

2.01e-0526603DOID:11168 (is_marker_for)
Diseasehepatitis C (is_marker_for)

KLRK1 TLR9 NCR1

4.99e-0535603DOID:1883 (is_marker_for)
DiseaseNephronophthisis, familial juvenile

ANKS6 MAPKBP1

8.48e-057602C1855681
DiseaseSmall cell carcinoma of lung

TTBK2 TMEM132D DIP2C

1.84e-0454603C0149925
DiseaseOpioid use measurement

AEBP2 NCR1

4.20e-0415602EFO_0009937
Diseaseproteinuria (implicated_via_orthology)

ANKS6 SORCS1

1.71e-0330602DOID:576 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
HRVSLGDTWSRQMHP

ACOX2

6

Q99424
SQSWLQRHMLTHSGD

AEBP2

311

Q6ZN18
ESEHHWDMVRRHLQG

ERVK-18

456

O42043
ESEHHWDMVRRHLQG

ERVK-9

566

Q9UKH3
LHAARWHQRDRGTMW

ARSL

461

P51690
GVPRVNGEQHHWDMS

PCDH17

691

O14917
DVQGDGRWMSLHHRF

PAFAH1B3

16

Q15102
RHANSGVATDFMHWQ

HDC

336

P19113
SEIMNMLWHRLNDHG

ENTHD1

51

Q8IYW4
RRDHHTMTVLWGTQE

EFCAB2

131

Q5VUJ9
GQMERSPRRTHHWQH

MBD6

901

Q96DN6
HALWDHTAQNLLRMG

NCR1

246

O76036
WHSSSRGHDGMSQRS

GPBP1L1

96

Q9HC44
RLVIGHDSTGMHASW

LOXHD1

751

Q8IVV2
GRRSRHSWEMSEFHN

KLRK1

6

P26718
NWVRMAAAEHRHSSG

NPIPB8

231

E9PQR5
SGGDDRRVLLWHMEQ

DCAF5

71

Q96JK2
SDWGHHPRIERASMD

LRP2

1571

P98164
MGNHTWEGCHVDSRV

GPR4

1

P46093
ATESRMHWPGREVHE

GABRR1

21

P24046
SGAHVDSARLQMHWE

C17orf99

106

Q6UX52
WRIHVDQMHQHRSGI

IFT57

261

Q9NWB7
RNEGDLFHRLWHIMN

DOCK4

106

Q8N1I0
GSMSWGAMHGRDHRR

CPEB2

136

Q7Z5Q1
QGHSHWEETSMRRME

GBGT1

171

Q8N5D6
ESEHHWDMVRRHLQG

ERVK-7

456

P61567
DSGAHWQLHRRLAMA

CYP17A1

116

P05093
GSINMEHWISQAIHG

DIP2C

156

Q9Y2E4
MHWALVAHRDQRDIN

DIP2C

596

Q9Y2E4
HGHEAVVRLLMEWGA

ANKS6

201

Q68DC2
ESEHHWDMVRRHLQG

ERVK-21

566

P61565
GHMPAVRVWDVAEHS

MAPKBP1

111

O60336
HWDMVRCHLQGREDN

HERVK_113

571

Q902F9
VGHFSREGWMVRVHQ

METTL13

171

Q8N6R0
GHPEEMERWHTGNRH

HELZ2

286

Q9BYK8
MERWHTGNRHVVPGV

HELZ2

291

Q9BYK8
NWVRMVAAEHRHSSG

NPIPB6

231

E9PJ23
WAINRVAMEIQHRSH

PRSS56

51

P0CW18
MAHRGAHFAFRSRWQ

NTMT2

1

Q5VVY1
WARHGESGSMAVFHQ

PVR

66

P15151
RTLQGHGHWVNTMAL

NLE1

281

Q9NVX2
SHREWGQEMVGRGMH

SVOP

521

Q8N4V2
VWHAASGLMGRTLHR

SNAP47

371

Q5SQN1
AEHLGEMNRQWHRVH

SYNE2

5141

Q8WXH0
EGMSHSHDWVGLSNR

TMEM132D

956

Q14C87
DQDHVDRLSSGRWMG

MYCBP2

4236

O75592
SDRGHAEMAIALWNN

PLB1

1351

Q6P1J6
RKRSWEEHVTHWMGQ

DLC1

6

Q96QB1
MRERYHIQGSVGHDW

CNFN

76

Q9BYD5
RMSGLTRHQWIHTGE

ZNF460

431

Q14592
HKNREMGRHDDLWSL

TTBK1

211

Q5TCY1
WAQLGMALTRDNHHF

TLR9

1006

Q9NR96
TQLGNHDRNPETWHM

ZSCAN5B

31

A6NJL1
NAHRNREMGRHDDLW

TTBK2

196

Q6IQ55
WSSNLMEHKRIHTGE

ZNF728

491

P0DKX0
AMMGDTHWRVAHERD

TRPV6

616

Q9H1D0
TGAHWMRQPVSFHRV

TBX6

181

O95947
MDAGAASREHARWQG

SAFB2

866

Q14151
QDTWAGHGQRHLMEA

ZNF518A

1461

Q6AHZ1
GHGQRHLMEATRDWN

ZNF518A

1466

Q6AHZ1
HARGGHWLAVRMGRD

TJP3

516

O95049
WSSNLMEHKRIHTGE

ZNF208

1096

O43345
VGHWDGNMSLVDRRT

WDR76

421

Q9H967
AGLGHWDGVTHEMRR

TMEM221

261

A6NGB7
LWGSQLTRHQRMHTG

ZNF790

516

Q6PG37
GSEWERHVLRHGMAL

ZNF462

2426

Q96JM2
GTHRGWAAVQMRLLH

TRAPPC9

451

Q96Q05
ALTGDSAHNQAMVHW

SORCS1

166

Q8WY21
EWEVGHSIRTLAMHR

XKRX

151

Q6PP77
ARQWPEVRAHMAQHS

ZNF335

1056

Q9H4Z2
WMSHGQRHLIEATRD

ZNF518B

1051

Q9C0D4
AHWGRHVRNLHKTVM

NDUFV2

16

P19404