Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	BPTF ZNF746 GMEB2 KDM6B RREB1	7.86e-04	1244	13	5	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	BPTF ZNF746 GMEB2 KDM6B RREB1	8.67e-04	1271	13	5	GO:0000987
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	BPTF ZNF746 GMEB2 KDM6B RREB1	1.62e-03	1459	13	5	GO:0000977
Domain	PHD	BPTF PHRF1	1.21e-03	75	13	2	PF00628
Domain	Znf_PHD-finger	BPTF PHRF1	1.34e-03	79	13	2	IPR019787
Domain	PHD	BPTF PHRF1	1.69e-03	89	13	2	SM00249
Domain	Znf_PHD	BPTF PHRF1	1.77e-03	91	13	2	IPR001965
Domain	ZF_PHD_2	BPTF PHRF1	1.93e-03	95	13	2	PS50016
Domain	ZF_PHD_1	BPTF PHRF1	1.97e-03	96	13	2	PS01359
Domain	-	NSMCE2 BPTF PHRF1	3.30e-03	449	13	3	3.30.40.10
Domain	Znf_RING/FYVE/PHD	NSMCE2 BPTF PHRF1	3.51e-03	459	13	3	IPR013083
Domain	Znf_FYVE_PHD	BPTF PHRF1	4.53e-03	147	13	2	IPR011011
Domain	ZINC_FINGER_C2H2_2	ZNF746 ZNF804B RREB1	1.49e-02	775	13	3	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF746 ZNF804B RREB1	1.50e-02	777	13	3	PS00028
Domain	Znf_C2H2-like	ZNF746 ZNF804B RREB1	1.60e-02	796	13	3	IPR015880
Domain	Znf_C2H2	ZNF746 ZNF804B RREB1	1.65e-02	805	13	3	IPR007087
Domain	ZnF_C2H2	ZNF746 ZNF804B RREB1	1.67e-02	808	13	3	SM00355
Domain	zf-C2H2_6	ZNF746 RREB1	1.94e-02	314	13	2	PF13912
Pubmed	Development of an efficient screening system to identify novel bone metabolism-related genes using the exchangeable gene trap mutagenesis mouse models.	BPTF WBP1L	7.62e-05	35	13	2	28106071
Pubmed	Tagging genes with cassette-exchange sites.	NSMCE2 BPTF PHRF1	2.36e-04	335	13	3	15741177
Pubmed	Interaction network of human early embryonic transcription factors.	BPTF ZNF746 RREB1	2.70e-04	351	13	3	38297188
Interaction	ELK3 interactions	ZNF746 GMEB2 RREB1	5.64e-05	120	13	3	int:ELK3
GeneFamily	PHD finger proteins	BPTF PHRF1	8.62e-04	90	9	2	88
Computational	Genes upregulated in subsets of cells of a given type within various tumors	GJB3 KDM6B	3.14e-04	50	6	2	GAVISH_3CA_METAPROGRAM_EPITHELIAL_EPI3
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	BPTF GJB3 GMEB2 RREB1	2.34e-06	176	13	4	6546_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	BPTF GJB3 GMEB2	1.11e-04	170	13	3	3791_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A_EA	BPTF GMEB2 RREB1	1.15e-04	172	13	3	1072_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	BPTF GJB3 RREB1	1.17e-04	173	13	3	5950_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	BPTF GMEB2 KDM6B	1.17e-04	173	13	3	2881_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	BPTF GJB3 GMEB2	1.17e-04	173	13	3	2084_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	BPTF GJB3 GMEB2	1.21e-04	175	13	3	6736_DN
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A_EA	BPTF GMEB2 RREB1	1.21e-04	175	13	3	1058_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	BPTF GJB3 GMEB2	1.21e-04	175	13	3	6316_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	BPTF GJB3 GMEB2	1.23e-04	176	13	3	1212_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	BPTF GMEB2 KDM6B	1.29e-04	179	13	3	4483_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	BPTF GJB3 GMEB2	1.31e-04	180	13	3	1793_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HG-U133A	BPTF GJB3 GMEB2	1.35e-04	182	13	3	1891_DN
Drug	0179445-0000 [211246-22-9]; Down 200; 10uM; MCF7; HT_HG-U133A	BPTF WBP1L RREB1	1.35e-04	182	13	3	3630_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HG-U133A	BPTF GJB3 GMEB2	1.35e-04	182	13	3	1951_DN
Drug	Camptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A	BPTF GMEB2 RREB1	1.40e-04	184	13	3	2321_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	BPTF GMEB2 RREB1	1.44e-04	186	13	3	6874_DN
Disease	anemia (phenotype), response to ribavirin	ZNF804B PHRF1	6.44e-06	9	13	2	EFO_0004272, GO_1901559
Disease	Peripheral Nervous System Diseases	CACNA1B GJB3	2.53e-04	54	13	2	C4721453
Disease	Intellectual Disability	CACNA1B BPTF KDM6B	8.82e-04	447	13	3	C3714756
Disease	Oral ulcer	NSMCE2 RREB1	9.90e-04	107	13	2	HP_0000155
Disease	monocyte count	NSMCE2 WBP1L ZNF746 RREB1	2.06e-03	1320	13	4	EFO_0005091
Disease	eosinophil count	NSMCE2 BPTF GMEB2 KDM6B	3.19e-03	1488	13	4	EFO_0004842
Disease	eosinophil percentage of leukocytes	NSMCE2 BPTF KDM6B	3.81e-03	746	13	3	EFO_0007991
Disease	response to paliperidone, schizophrenia symptom severity measurement	NSMCE2 CACNA1B	3.95e-03	216	13	2	EFO_0007925, EFO_0007927
Disease	eosinophil percentage of granulocytes	BPTF KDM6B	4.61e-03	234	13	2	EFO_0007996
Disease	basophil count, eosinophil count	BPTF KDM6B	4.88e-03	241	13	2	EFO_0004842, EFO_0005090
Disease	hypothyroidism	ZNF804B PHRF1	6.71e-03	284	13	2	EFO_0004705
Disease	Inguinal hernia	BPTF RREB1	6.85e-03	287	13	2	HP_0000023
Disease	lymphocyte:monocyte ratio	WBP1L KDM6B	6.90e-03	288	13	2	EFO_0600088
Disease	platelet crit	NSMCE2 KDM6B RREB1	7.51e-03	952	13	3	EFO_0007985
Disease	Parkinson disease	CACNA1B WBP1L	8.50e-03	321	13	2	MONDO_0005180
Disease	grip strength measurement	BPTF WBP1L	1.00e-02	350	13	2	EFO_0006941
Disease	free androgen index	WBP1L RREB1	1.14e-02	374	13	2	EFO_0007005
Disease	smoking status measurement	BPTF WBP1L ZNF804B	1.29e-02	1160	13	3	EFO_0006527
Disease	C-reactive protein measurement	NSMCE2 BPTF RREB1	1.43e-02	1206	13	3	EFO_0004458

Protein segments in the cluster

Peptide	Gene	Start	Entry
EVKKRRHRLKRHNDC	DEPDC7	51	Q96QD5
QHREDHDKRRHLAHK	BPTF	866	Q12830
HHHHRCHRRRDRKQR	CACNA1B	2051	Q00975
RRRDHHMVQRHLCDH	ADAMTS14	876	Q8WXS8
QQCDEHRRRAKELKH	GMEB2	321	Q9UKD1
SCKRRQKEHQKEHRR	KDM6B	971	O15054
QKEHQKEHRRHRRAC	KDM6B	976	O15054
LRRAIENHNKKRHRH	NSMCE2	231	Q96MF7
RLCRHKHQRERSHER	PHRF1	1131	Q9P1Y6
RERRHRQKHGDQCAK	GJB3	101	O75712
CFHKREHHSVERHKR	ZNF804B	741	A4D1E1
VRHQRIHQKARHAKH	RREB1	1556	Q92766
IRKDHLRKHQRNHAA	ZNF746	576	Q6NUN9
CHHRRAKHRLQAQQR	WBP1L	61	Q9NX94