Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	aldose reductase (NADPH) activity	AKR1B10 AKR1D1 AKR1B15	2.27e-05	14	81	3	GO:0004032
GeneOntologyMolecularFunction	indanol dehydrogenase activity	AKR1B10 AKR1B15	9.70e-05	4	81	2	GO:0047718
GeneOntologyMolecularFunction	allyl-alcohol dehydrogenase activity	AKR1B10 AKR1B15	9.70e-05	4	81	2	GO:0047655
GeneOntologyMolecularFunction	alcohol dehydrogenase (NADP+) activity	AKR1B10 AKR1D1 AKR1B15	1.75e-04	27	81	3	GO:0008106
GeneOntologyMolecularFunction	ferroxidase activity	HEPHL1 HEPH	2.41e-04	6	81	2	GO:0004322
GeneOntologyMolecularFunction	geranylgeranyl reductase activity	AKR1B10 AKR1B15	2.41e-04	6	81	2	GO:0045550
GeneOntologyMolecularFunction	oxidoreductase activity, acting on metal ions, oxygen as acceptor	HEPHL1 HEPH	2.41e-04	6	81	2	GO:0016724
GeneOntologyMolecularFunction	aldo-keto reductase (NADPH) activity	AKR1B10 AKR1D1 AKR1B15	2.93e-04	32	81	3	GO:0004033
GeneOntologyMolecularFunction	small GTPase binding	ANKFY1 SYTL2 RAPGEF4 LRRK2 DAAM2 SGSM3 DAAM1	3.27e-04	321	81	7	GO:0031267
GeneOntologyMolecularFunction	kinase binding	RB1 FEZ1 KSR2 FAM83E FAM83G FAM83D AKAP11 RYR2 FAM83A FAM83H FAM83B NRP1	5.12e-04	969	81	12	GO:0019900
GeneOntologyMolecularFunction	steroid dehydrogenase activity	AKR1B10 AKR1D1 AKR1B15	5.29e-04	39	81	3	GO:0016229
GeneOntologyMolecularFunction	NADP+ binding	AKR1B10 AKR1B15	5.74e-04	9	81	2	GO:0070401
GeneOntologyMolecularFunction	GTPase binding	ANKFY1 SYTL2 RAPGEF4 LRRK2 DAAM2 SGSM3 DAAM1	6.47e-04	360	81	7	GO:0051020
GeneOntologyMolecularFunction	protein kinase binding	FEZ1 KSR2 FAM83E FAM83G FAM83D AKAP11 RYR2 FAM83A FAM83H FAM83B NRP1	7.74e-04	873	81	11	GO:0019901
GeneOntologyMolecularFunction	retinal dehydrogenase activity	AKR1B10 AKR1B15	1.43e-03	14	81	2	GO:0001758
GeneOntologyMolecularFunction	phosphatidylinositol 3-kinase regulatory subunit binding	FAM83A FAM83B	1.43e-03	14	81	2	GO:0036312
GeneOntologyMolecularFunction	all-trans-retinol dehydrogenase (NADP+) activity	AKR1B10 AKR1B15	1.65e-03	15	81	2	GO:0052650
GeneOntologyMolecularFunction	protein kinase A binding	LRRK2 AKAP11 RYR2	1.69e-03	58	81	3	GO:0051018
GeneOntologyMolecularFunction	ATP-dependent activity, acting on DNA	MCM5 RUVBL2 RAD17 CDK7	1.78e-03	127	81	4	GO:0008094
GeneOntologyMolecularFunction	protein kinase A catalytic subunit binding	AKAP11 RYR2	1.88e-03	16	81	2	GO:0034236
GeneOntologyMolecularFunction	3'-5' exonuclease activity	EXOSC10 EXD1 POLRMT	1.95e-03	61	81	3	GO:0008408
GeneOntologyMolecularFunction	ATP hydrolysis activity	DNAH3 GET3 MCM5 RUVBL2 DNAH8 ATP8B2 RAD17	2.08e-03	441	81	7	GO:0016887
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH3 DNAH8	2.38e-03	18	81	2	GO:0008569
GeneOntologyMolecularFunction	oxidoreductase activity, acting on metal ions	HEPHL1 HEPH	2.38e-03	18	81	2	GO:0016722
GeneOntologyMolecularFunction	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	AKR1B10 AKR1B15	2.94e-03	20	81	2	GO:0004303
GeneOntologyMolecularFunction	phosphatidylcholine transporter activity	SCP2 ATP8B2	2.94e-03	20	81	2	GO:0008525
GeneOntologyMolecularFunction	retinal binding	AKR1B10 AKR1B15	3.25e-03	21	81	2	GO:0016918
GeneOntologyMolecularFunction	ATP-dependent activity	DNAH3 GET3 MCM5 RUVBL2 DNAH8 ATP8B2 RAD17 CDK7	3.42e-03	614	81	8	GO:0140657
GeneOntologyMolecularFunction	protein kinase A regulatory subunit binding	AKAP11 RYR2	4.59e-03	25	81	2	GO:0034237
Domain	DUF1669	FAM83E FAM83G FAM83D FAM83A FAM83H FAM83B	2.22e-13	8	86	6	IPR012461
Domain	DUF1669	FAM83E FAM83G FAM83D FAM83A FAM83H FAM83B	2.22e-13	8	86	6	PF07894
Domain	ALDOKETO_REDUCTASE_1	AKR1B10 AKR1D1 AKR1B15	1.11e-05	10	86	3	PS00798
Domain	Aldo/ket_reductase_CS	AKR1B10 AKR1D1 AKR1B15	1.11e-05	10	86	3	IPR018170
Domain	Aldo/keto_reductase	AKR1B10 AKR1D1 AKR1B15	1.11e-05	10	86	3	IPR020471
Domain	ALDOKETO_REDUCTASE_2	AKR1B10 AKR1D1 AKR1B15	1.11e-05	10	86	3	PS00062
Domain	ALDOKETO_REDUCTASE_3	AKR1B10 AKR1D1 AKR1B15	1.11e-05	10	86	3	PS00063
Domain	Miga	MIGA2 MIGA1	2.10e-05	2	86	2	IPR019392
Domain	Miga	MIGA2 MIGA1	2.10e-05	2	86	2	PF10265
Domain	-	AKR1B10 AKR1D1 AKR1B15	5.05e-05	16	86	3	3.20.20.100
Domain	NADP_OxRdtase_dom	AKR1B10 AKR1D1 AKR1B15	6.12e-05	17	86	3	IPR023210
Domain	Aldo_ket_red	AKR1B10 AKR1D1 AKR1B15	6.12e-05	17	86	3	PF00248
Domain	Aldo/ket_red/Kv-b	AKR1B10 AKR1D1 AKR1B15	6.12e-05	17	86	3	IPR001395
Domain	MULTICOPPER_OXIDASE2	HEPHL1 HEPH	6.27e-05	3	86	2	PS00080
Domain	Cu-oxidase_2	HEPHL1 HEPH	1.25e-04	4	86	2	IPR011706
Domain	Cu-oxidase_2	HEPHL1 HEPH	1.25e-04	4	86	2	PF07731
Domain	35EXOc	EXOSC10 EXD1	2.08e-04	5	86	2	SM00474
Domain	Cu_oxidase_CS	HEPHL1 HEPH	2.08e-04	5	86	2	IPR033138
Domain	DNA_pol_A_exo1	EXOSC10 EXD1	2.08e-04	5	86	2	PF01612
Domain	Cu-oxidase_3	HEPHL1 HEPH	2.08e-04	5	86	2	IPR011707
Domain	MULTICOPPER_OXIDASE1	HEPHL1 HEPH	2.08e-04	5	86	2	PS00079
Domain	3'-5'_exonuclease_dom	EXOSC10 EXD1	2.08e-04	5	86	2	IPR002562
Domain	Cu-oxidase_3	HEPHL1 HEPH	2.08e-04	5	86	2	PF07732
Domain	Cu_oxidase_Cu_BS	HEPHL1 HEPH	3.11e-04	6	86	2	IPR002355
Domain	DAD_dom	DAAM2 DAAM1	5.76e-04	8	86	2	IPR014767
Domain	DAD	DAAM2 DAAM1	5.76e-04	8	86	2	PS51231
Domain	Drf_GBD	DAAM2 DAAM1	7.39e-04	9	86	2	PF06371
Domain	FH3_dom	DAAM2 DAAM1	7.39e-04	9	86	2	IPR010472
Domain	GTPase-bd	DAAM2 DAAM1	7.39e-04	9	86	2	IPR010473
Domain	Drf_FH3	DAAM2 DAAM1	7.39e-04	9	86	2	PF06367
Domain	Drf_FH3	DAAM2 DAAM1	7.39e-04	9	86	2	SM01139
Domain	Drf_GBD	DAAM2 DAAM1	7.39e-04	9	86	2	SM01140
Domain	GBD/FH3_dom	DAAM2 DAAM1	1.12e-03	11	86	2	IPR014768
Domain	GBD_FH3	DAAM2 DAAM1	1.12e-03	11	86	2	PS51232
Domain	-	HEPHL1 HEPH	1.84e-03	14	86	2	2.60.40.420
Domain	Dynein_heavy_chain_D4_dom	DNAH3 DNAH8	1.84e-03	14	86	2	IPR024317
Domain	Dynein_HC_stalk	DNAH3 DNAH8	1.84e-03	14	86	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH3 DNAH8	1.84e-03	14	86	2	IPR013602
Domain	DHC_N2	DNAH3 DNAH8	1.84e-03	14	86	2	PF08393
Domain	MT	DNAH3 DNAH8	1.84e-03	14	86	2	PF12777
Domain	AAA_8	DNAH3 DNAH8	1.84e-03	14	86	2	PF12780
Domain	ATPase_dyneun-rel_AAA	DNAH3 DNAH8	1.84e-03	14	86	2	IPR011704
Domain	AAA_5	DNAH3 DNAH8	1.84e-03	14	86	2	PF07728
Domain	DHC_fam	DNAH3 DNAH8	2.12e-03	15	86	2	IPR026983
Domain	Dynein_heavy_dom	DNAH3 DNAH8	2.12e-03	15	86	2	IPR004273
Domain	FH2	DAAM2 DAAM1	2.12e-03	15	86	2	PS51444
Domain	Dynein_heavy	DNAH3 DNAH8	2.12e-03	15	86	2	PF03028
Domain	FH2_Formin	DAAM2 DAAM1	2.12e-03	15	86	2	IPR015425
Domain	FH2	DAAM2 DAAM1	2.12e-03	15	86	2	PF02181
Domain	FH2	DAAM2 DAAM1	2.12e-03	15	86	2	SM00498
Domain	AAA+_ATPase	DNAH3 RUVBL2 DNAH8 RAD17	4.41e-03	144	86	4	IPR003593
Domain	AAA	DNAH3 RUVBL2 DNAH8 RAD17	4.41e-03	144	86	4	SM00382
Domain	Cupredoxin	HEPHL1 HEPH	4.56e-03	22	86	2	IPR008972
Pubmed	The DUF1669 domain of FAM83 family proteins anchor casein kinase 1 isoforms.	FAM83E FAM83G FAM83D FAM83A FAM83H FAM83B	9.40e-14	11	87	6	29789297
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	ESYT2 URB1 ANKFY1 SYNE2 AKAP11 TNKS1BP1 MINAR1 ADGRV1 HEPH	5.60e-09	225	87	9	12168954
Pubmed	Conserved oncogenic behavior of the FAM83 family regulates MAPK signaling in human cancer.	FAM83E FAM83D FAM83A	1.51e-07	5	87	3	24736947
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CD2BP2 SYTL2 GPAM MINAR1 GRIN3A UBN2 FAM135A ATP8B2 DOP1A CCSER1	4.51e-07	493	87	10	15368895
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ZNF532 HECW2 FBF1 AKAP11 TNKS1BP1 POGZ DAAM1 ADGRV1 HEPH NUP205	8.54e-07	529	87	10	14621295
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	EXOSC10 URB1 ANKFY1 RB1 EIF2B3 ASPH POLRMT AP1M1 MCM5 POGZ HUWE1 RUVBL2 PHLDB2 FAM83H NUP205	1.24e-06	1353	87	15	29467282
Pubmed	GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.	ESYT2 EXOSC10 URB1 GET3 POLRMT HUWE1 RUVBL2	1.44e-06	221	87	7	29991511
Pubmed	Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.	ZNF555 TAMM41 SYNE2 EIF2B3 GPAM POGZ ADGRV1 FBXO21 RUVBL2 FAM135A RAD17	2.76e-06	750	87	11	11230166
Pubmed	A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.	CD2BP2 GET3 SYNE2 KSR2 MCM5 RUVBL2 GPRASP2 FAM83H	3.72e-06	363	87	8	25036637
Pubmed	Role of AKR1B10 and AKR1B8 in the pathogenesis of non-alcoholic steatohepatitis (NASH) in mouse.	AKR1B10 AKR1B15	6.19e-06	2	87	2	34954342
Pubmed	Aldo-keto reductase family 1 member B8 is secreted via non-classical pathway.	AKR1B10 AKR1B15	6.19e-06	2	87	2	25120755
Pubmed	Murine aldo-keto reductase family 1 subfamily B: identification of AKR1B8 as an ortholog of human AKR1B10.	AKR1B10 AKR1B15	6.19e-06	2	87	2	21087085
Pubmed	Tissue-specific expression of two aldose reductase-like genes in mice: abundant expression of mouse vas deferens protein and fibroblast growth factor-regulated protein in the adrenal gland.	AKR1B10 AKR1B15	6.19e-06	2	87	2	8526877
Pubmed	AKR1B8 deficiency drives severe DSS-induced acute colitis through invasion of luminal bacteria and activation of innate immunity.	AKR1B10 AKR1B15	6.19e-06	2	87	2	36518763
Pubmed	Intestinal Paneth cell differentiation relies on asymmetric regulation of Wnt signaling by Daam1/2.	DAAM2 DAAM1	6.19e-06	2	87	2	38000028
Pubmed	1.7 A structure of FR-1, a fibroblast growth factor-induced member of the aldo-keto reductase family, complexed with coenzyme and inhibitor.	AKR1B10 AKR1B15	6.19e-06	2	87	2	7578036
Pubmed	Characterization of the promoter of the gene for a mouse vas deferens protein related to the aldo-keto reductase superfamily: effect of steroid hormones and phorbol esters.	AKR1B10 AKR1B15	6.19e-06	2	87	2	8541228
Pubmed	Mitoguardin-1 and -2 promote maturation and the developmental potential of mouse oocytes by maintaining mitochondrial dynamics and functions.	MIGA2 MIGA1	6.19e-06	2	87	2	26716412
Pubmed	Impaired Barrier Function and Immunity in the Colon of Aldo-Keto Reductase 1B8 Deficient Mice.	AKR1B10 AKR1B15	6.19e-06	2	87	2	33644071
Pubmed	Aspartate beta-hydroxylase promotes cholangiocarcinoma progression by modulating RB1 phosphorylation.	RB1 ASPH	6.19e-06	2	87	2	29733964
Pubmed	Identification of chick and mouse Daam1 and Daam2 genes and their expression patterns in the central nervous system.	DAAM2 DAAM1	6.19e-06	2	87	2	15464228
Pubmed	Impaired self-renewal and increased colitis and dysplastic lesions in colonic mucosa of AKR1B8-deficient mice.	AKR1B10 AKR1B15	6.19e-06	2	87	2	25538260
Pubmed	Functional expression of novel human and murine AKR1B genes.	AKR1B10 AKR1B15	6.19e-06	2	87	2	21276782
Pubmed	Compensatory upregulation of aldo-keto reductase 1B10 to protect hepatocytes against oxidative stress during hepatocarcinogenesis.	AKR1B10 AKR1B15	6.19e-06	2	87	2	31911858
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	EXOSC10 URB1 GET3 SYNE2 MCM5 HUWE1 RUVBL2 PHLDB2 FAM83H FAM83B NUP205 NRP1	9.28e-06	1024	87	12	24711643
Pubmed	Identification of proteins that may directly interact with human RPA.	RB1 MCM5 RAD17	1.00e-05	17	87	3	20679368
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	ESYT2 SYNE2 FAM83G AP1M1 AKAP11 TNKS1BP1 PHLDB2 FAM83H DOP1A FAM83B CCSER1	1.02e-05	861	87	11	36931259
Pubmed	From ORFeome to biology: a functional genomics pipeline.	ZNF555 RB1 EIF2B3 GPAM POGZ RUVBL2 FAM135A GPRASP2 RAD17 CDK7	1.33e-05	722	87	10	15489336
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	EXOSC10 CD2BP2 ASPH POLRMT AP1M1 MCM5 TNKS1BP1 RUVBL2 PHLDB2 FAM83H FAM83B NUP205 CDK7	1.44e-05	1257	87	13	36526897
Pubmed	Substrate specificity and catalytic efficiency of aldo-keto reductases with phospholipid aldehydes.	AKR1B10 AKR1B15	1.85e-05	3	87	2	17381426
Pubmed	A delayed-early gene activated by fibroblast growth factor-1 encodes a protein related to aldose reductase.	AKR1B10 AKR1B15	1.85e-05	3	87	2	7510692
Pubmed	Pancreatic cancer-derived exosomal microRNA-19a induces β-cell dysfunction by targeting ADCY1 and EPAC2.	RAPGEF4 ADCY1	1.85e-05	3	87	2	34512170
Pubmed	[Ceruloplasmin, hephaestin and zyklopen: the three multicopper oxidases important for human iron metabolism].	HEPHL1 HEPH	1.85e-05	3	87	2	24988611
Pubmed	Identification and comparative expression analyses of Daam genes in mouse and Xenopus.	DAAM2 DAAM1	1.85e-05	3	87	2	15533824
Pubmed	DNA cloning using in vitro site-specific recombination.	EVC2 ZNF555 EIF2B3 GPAM POGZ RUVBL2 FAM135A GPRASP2 RAD17 CDK7	2.98e-05	794	87	10	11076863
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	ESYT2 EXOSC10 ANKFY1 AP1M1 MCM5 HUWE1 RUVBL2 FAM83H NUP205	3.20e-05	638	87	9	33239621
Pubmed	Human and mouse cyclin D2 splice variants: transforming activity and subcellular localization.	RB1 CDK7	3.70e-05	4	87	2	17873913
Pubmed	Disheveled-associated activator of morphogenesis 2 promotes invasion of colorectal cancer by activating PAK1 and promoting MMP7 expression.	DAAM2 DAAM1	3.70e-05	4	87	2	33974241
Pubmed	Protein protein interactions between triadin and calsequestrin are involved in modulation of sarcoplasmic reticulum calcium release in cardiac myocytes.	ASPH RYR2	3.70e-05	4	87	2	17569730
Pubmed	Viral gene transfer rescues arrhythmogenic phenotype and ultrastructural abnormalities in adult calsequestrin-null mice with inherited arrhythmias.	ASPH RYR2	3.70e-05	4	87	2	22298808
Pubmed	Identification of genes and networks driving cardiovascular and metabolic phenotypes in a mouse F2 intercross.	AKR1B10 AKR1B15	3.70e-05	4	87	2	21179467
Pubmed	DAAM1 and DAAM2 are co-required for myocardial maturation and sarcomere assembly.	RB1 DAAM2 DAAM1	3.77e-05	26	87	3	26526197
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	EXOSC10 URB1 SYNE2 POLRMT MCM5 TNKS1BP1 POGZ HUWE1 NUP205	3.83e-05	653	87	9	22586326
Pubmed	Proteomic identification of the MYST domain histone acetyltransferase TIP60 (HTATIP) as a co-activator of the myeloid transcription factor C/EBPalpha.	RB1 MCM5 GRIN3A	5.27e-05	29	87	3	18239623
Pubmed	Mitochondrial Function Regulated by Mitoguardin-1/2 Is Crucial for Ovarian Endocrine Functions and Ovulation.	MIGA2 MIGA1	6.16e-05	5	87	2	28938432
Pubmed	Cross-Species Genomics Identifies TAF12, NFYC, and RAD54L as Choroid Plexus Carcinoma Oncogenes.	RB1 TAF12	6.16e-05	5	87	2	25965574
Pubmed	Comparisons of genomic structures and chromosomal locations of the mouse aldose reductase and aldose reductase-like genes.	AKR1B10 AKR1B15	6.16e-05	5	87	2	10092857
Pubmed	Analysis of pRb, p16INK4A proteins and proliferating antigens: PCNA, Ki-67 and MCM5 expression in aggressive fibromatosis (desmoid tumor).	RB1 MCM5	6.16e-05	5	87	2	19130399
Pubmed	Complementary DNA cloning, genomic characterization and expression analysis of a mammalian gene encoding histidine-rich calcium binding protein.	ASPH RYR2	6.16e-05	5	87	2	15777620
Pubmed	Epac2 mediates cardiac β1-adrenergic-dependent sarcoplasmic reticulum Ca2+ leak and arrhythmia.	RAPGEF4 RYR2	6.16e-05	5	87	2	23363625
Pubmed	Mitoguardin Regulates Mitochondrial Fusion through MitoPLD and Is Required for Neuronal Homeostasis.	MIGA2 MIGA1	6.16e-05	5	87	2	26711011
Pubmed	Mitochondrial dynamics controls anti-tumour innate immunity by regulating CHIP-IRF1 axis stability.	MIGA2 MIGA1	6.16e-05	5	87	2	29180626
Pubmed	Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1.	DAAM2 DAAM1	6.16e-05	5	87	2	11779461
Pubmed	Butylated hydroxyanisole induces distinct expression patterns of Nrf2 and detoxification enzymes in the liver and small intestine of C57BL/6 mice.	AKR1B10 AKR1B15	6.16e-05	5	87	2	26291391
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	NWD2 SYNE2 HUWE1 FBXO21	6.94e-05	87	87	4	12465718
Pubmed	The LIFEdb database in 2006.	ZNF555 EIF2B3 GPAM POGZ RUVBL2 FAM135A GPRASP2 RAD17 CDK7	8.09e-05	720	87	9	16381901
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	ESYT2 ZNF532 KSR2 ASPH SCP2 DAAM1 ADGRV1 HUWE1 UBN2 FBXO21 ADCY1 DOP1A NRP1	8.25e-05	1489	87	13	28611215
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ANKFY1 ZNF532 POLRMT TNKS1BP1 POGZ HUWE1 GPRASP2	8.81e-05	418	87	7	34709266
Pubmed	Recruitment of Pontin/Reptin by E2f1 amplifies E2f transcriptional response during cancer progression.	RB1 RUVBL2	9.22e-05	6	87	2	26639898
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	CRYBG2 URB1 B4GALNT4 CD2BP2 EIF2B3 KSR2 POLRMT MCM5 TNKS1BP1 HUWE1 FAM83H	9.78e-05	1105	87	11	35748872
Pubmed	Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS.	FAM83G FAM83D AKAP11 FAM83H FAM83B NRP1 CDK7	1.08e-04	432	87	7	23455922
Pubmed	mTOR Inhibition via Rapamycin Treatment Partially Reverts the Deficit in Energy Metabolism Caused by FH Loss in RPE Cells.	RB1 SYNE2 MCM5 RAD17	1.10e-04	98	87	4	34943047
Pubmed	A directed protein interaction network for investigating intracellular signal transduction.	URB1 FEZ1 GET3 SYNE2 MIPEP GPCPD1 FAM83D MCM5 SGSM3 GPRASP2 LCMT1	1.14e-04	1124	87	11	21900206
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	RB1 CD2BP2 TNKS1BP1 HUWE1 UBN2 RUVBL2 FAM135A FAM83B	1.15e-04	588	87	8	38580884
Pubmed	Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	ZNF532 SYTL2 GPAM HUWE1	1.24e-04	101	87	4	10997877
Pubmed	Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	AKAP11 DAAM1 ADGRV1 HEPH	1.29e-04	102	87	4	9734811
Pubmed	Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.	DNAH3 DNAH8	1.29e-04	7	87	2	9256245
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	ESYT2 HECW2 MCM5 HUWE1 RUVBL2 NRP1	1.39e-04	313	87	6	38270169
Pubmed	SARS-CoV-2 uses Spike glycoprotein to control the host's anaerobic metabolism by inhibiting LDHB.	ANKFY1 ASPH SCP2 AP1M1 MCM5 HUWE1 RUVBL2 NUP205	1.43e-04	607	87	8	39147351
Pubmed	Placental defects lead to embryonic lethality in mice lacking the Formin and PCP proteins Daam1 and Daam2.	DAAM2 DAAM1	1.72e-04	8	87	2	32353019
Pubmed	Cyclin-dependent kinase-2 (Cdk2) forms an inactive complex with cyclin D1 since Cdk2 associated with cyclin D1 is not phosphorylated by Cdk7-cyclin-H.	RB1 CDK7	2.20e-04	9	87	2	8647086
Pubmed	Genetic inactivation of Cdk7 leads to cell cycle arrest and induces premature aging due to adult stem cell exhaustion.	RB1 CDK7	2.20e-04	9	87	2	22505032
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	ESYT2 EXOSC10 URB1 SYNE2 EIF2B3 ASPH POLRMT MCM5 TNKS1BP1 HUWE1 UBN2 NUP205	2.44e-04	1440	87	12	30833792
Pubmed	Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.	ANKFY1 CD2BP2 MCM5 ADGRV1 HUWE1 FBXO21 RUVBL2	2.48e-04	495	87	7	28581483
Pubmed	SRp38 regulates alternative splicing and is required for Ca(2+) handling in the embryonic heart.	ASPH RYR2	2.75e-04	10	87	2	19386262
Pubmed	Both p16 and p21 families of cyclin-dependent kinase (CDK) inhibitors block the phosphorylation of cyclin-dependent kinases by the CDK-activating kinase.	RB1 CDK7	2.75e-04	10	87	2	7629134
Pubmed	c-Myc transformation domain recruits the human STAGA complex and requires TRRAP and GCN5 acetylase activity for transcription activation.	TAF12 RUVBL2	3.35e-04	11	87	2	12660246
Pubmed	Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors".	RB1 CDK7	3.35e-04	11	87	2	16782892
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	ESYT2 MIGA2 SYNE2 EIF2B3 MIPEP POLRMT SCP2 GPAM MIGA1 AKAP11 HUWE1 FAM83B	3.44e-04	1496	87	12	32877691
Pubmed	Proteomic analysis of exosomes from human neural stem cells by flow field-flow fractionation and nanoflow liquid chromatography-tandem mass spectrometry.	ANKFY1 SYNE2 DAAM2	3.61e-04	55	87	3	18570454
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	POLRMT AP1M1 MCM5 HUWE1 RUVBL2 DNAH8 LCMT1 NUP205	3.88e-04	704	87	8	29955894
Pubmed	Proteomic analysis of the NOS2 interactome in human airway epithelial cells.	AKR1B10 ASPH HUWE1 RUVBL2	4.09e-04	138	87	4	23438482
Pubmed	Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase.	ANKFY1 MCM5 TNKS1BP1 HUWE1 RUVBL2	4.70e-04	256	87	5	32698014
Pubmed	Sox2-Evf2 lncRNA-mediated mechanisms of chromosome topological control in developing forebrain.	AKR1B10 AKR1B15	4.74e-04	13	87	2	33593819
Pubmed	Diminished pancreatic beta-cell mass in securin-null mice is caused by beta-cell apoptosis and senescence.	RB1 RAD17	4.74e-04	13	87	2	19213844
Pubmed	Genomic analysis of synaptotagmin genes.	ESYT2 SYTL2	4.74e-04	13	87	2	11543631
Pubmed	hnRNP U protein is required for normal pre-mRNA splicing and postnatal heart development and function.	ASPH RYR2	4.74e-04	13	87	2	26039991
Pubmed	Alternative Functions of Cell Cycle-Related and DNA Repair Proteins in Post-mitotic Neurons.	RB1 RAD17 CDK7	4.90e-04	61	87	3	34746147
Pubmed	Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.	ESYT2 ASPH MCM5 TNKS1BP1 HUWE1 RUVBL2	5.07e-04	399	87	6	37536630
Pubmed	Expression of multiple formins in adult tissues and during developmental stages of mouse brain.	DAAM2 DAAM1	5.52e-04	14	87	2	26272686
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH3 DNAH8	5.52e-04	14	87	2	9373155
Pubmed	Genome-wide siRNA screen reveals amino acid starvation-induced autophagy requires SCOC and WAC.	NRBP2 FEZ1	5.52e-04	14	87	2	22354037
Pubmed	A Network of Conserved Synthetic Lethal Interactions for Exploration of Precision Cancer Therapy.	RB1 DAAM1 RAD17	5.90e-04	65	87	3	27453043
Pubmed	High-throughput screening of mouse knockout lines identifies true lean and obese phenotypes.	KSR2 GPAM	6.36e-04	15	87	2	18719666
Pubmed	Herpesvirus deconjugases inhibit the IFN response by promoting TRIM25 autoubiquitination and functional inactivation of the RIG-I signalosome.	HUWE1 RUVBL2 NUP205	6.45e-04	67	87	3	29357390
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	ESYT2 TAMM41 DAAM1 FAM135A PHLDB2 FAM83B	6.71e-04	421	87	6	36976175
Pubmed	Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning.	ADGRV1 ADCY1	7.26e-04	16	87	2	17567809
Pubmed	Identification of cAMP analogue inducible genes in RAW264 macrophages.	ASPH LRRK2	7.26e-04	16	87	2	11004510
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	ESYT2 EXOSC10 EIF2B3 ASPH POLRMT MCM5 HUWE1 FBXO21 NUP205	7.44e-04	974	87	9	28675297
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	EXOSC10 ASPH POLRMT AP1M1 TNKS1BP1 POGZ RUVBL2	7.87e-04	601	87	7	33658012
Interaction	CSNK1A1L interactions	FAM83G FAM83D FAM83A FAM83H FAM83B	4.55e-06	58	85	5	int:CSNK1A1L
Interaction	YWHAG interactions	ESYT2 SYNE2 KSR2 LRRK2 FAM83G AP1M1 MCM5 AKAP11 HUWE1 RUVBL2 GPRASP2 PHLDB2 FAM83H DOP1A FAM83B CDK7 CCSER1	1.50e-05	1248	85	17	int:YWHAG
Cytoband	Ensembl 112 genes in cytogenetic band chr7q33	AKR1B10 AKR1D1 AKR1B15 NUP205	4.72e-06	58	87	4	chr7q33
Cytoband	7q33	AKR1B10 AKR1B15 NUP205	6.65e-05	41	87	3	7q33
Cytoband	5q13	ADGRV1 RAD17	8.00e-04	22	87	2	5q13
GeneFamily	Aldo-keto reductases	AKR1B10 AKR1D1 AKR1B15	6.42e-06	15	45	3	399
GeneFamily	Dyneins, axonemal	DNAH3 DNAH8	8.04e-04	17	45	2	536
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	CD2BP2 SYTL2 AKAP11 MYO16	1.05e-03	181	45	4	694
Coexpression	GSE10147_IL3_VS_IL3_AND_HIVP17_STIM_PDC_UP	RB1 MIPEP AP1M1 AKAP11 POGZ RYR2	1.95e-05	166	87	6	M344
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HNBGABA	URB1 B4GALNT4 SYTL2 KSR2 DAAM1 GRIN3A UBN2 ADCY1 RYR2 DOP1A CCSER1	2.10e-05	703	87	11	M39070
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	LRRK2 IFI30 DAAM2 ADGRV1 DNAH8 RYR2	1.76e-06	186	87	6	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	TCGA-Skin-Primary_Tumor-Melanoma-Skin_Cutaneous_Melanoma-6\|TCGA-Skin / Sample_Type by Project: Shred V9	CRYBG2 AKR1B10 AKR1B15 HEPHL1 FAM83A FAM83B	1.82e-06	187	87	6	2ca7928baf0c5e61f7294ed05e6e6f0e0adf9d3f
ToppCell	COVID-19-kidney-TAL\|kidney / Disease (COVID-19 only), tissue and cell type	ZNF532 LRRK2 ADGRV1 FAM135A FAM83B CCSER1	2.38e-06	196	87	6	04f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCell	TCGA-Head_and_Esophagus\|World / Sample_Type by Project: Shred V9	CRYBG2 FAM83G HEPHL1 FAM83A FAM83B	2.21e-05	172	87	5	eb18aa179db1818f408c38e442ecfed8582d7dbc
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM83G AKAP11 DAAM1 FAM135A DOP1A	2.34e-05	174	87	5	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_A2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PAOX ESYT2 CRYBG2 IFI30 NRP1	2.40e-05	175	87	5	334fad1a147de6c007cec5089c02c35cf3220f1b
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KSR2 FAM83G AKAP11 DAAM1 FAM135A	2.60e-05	178	87	5	fcbbcc44271515de1969b4732b6441c012693d5f
ToppCell	10x5'v1-week_17-19-Myeloid_macrophage-stroma-monocytoid_macrophage\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	NRBP2 FEZ1 MINAR1 GRIN3A NRP1	2.75e-05	180	87	5	ba4c1fb55e8f1095bea6968417fefcf5f700926b
ToppCell	droplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HECW2 FAM83D DAAM2 ATP8B2 NRP1	2.82e-05	181	87	5	4df7972f88117108698efd06b124b232f8588981
ToppCell	droplet-Liver-hepatocytes-3m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HECW2 FAM83D DAAM2 ATP8B2 NRP1	2.82e-05	181	87	5	cbb530566893281289026bfd93adf721decd4ca3
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KSR2 LRRK2 FAM83E ADGRV1 CCSER1	3.05e-05	184	87	5	8fd8bd3d28d0ee6f0ef1f14e354d8eaf63a8081b
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDR1 NWD2 ASPH ADCY1 RYR2	3.13e-05	185	87	5	cdd75abdaa1ecedfd2e636203b83a6ac1782f0c3
ToppCell	normal_Pleural_Fluid-Myeloid_cells-Alveolar_Mac\|normal_Pleural_Fluid / Location, Cell class and cell subclass	FEZ1 POLRMT IFI30 PHLDB2 CC2D2B	3.21e-05	186	87	5	3314def702fe6a5056d0dadbb3a587c5d1a16412
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	B4GALNT4 SYTL2 DAAM2 ADCY1 RYR2	3.21e-05	186	87	5	4780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SYNE2 FAM83E TNKS1BP1 ADGRV1 PHLDB2	3.30e-05	187	87	5	58d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ESYT2 SYTL2 FAM135A FAM83B CCSER1	3.30e-05	187	87	5	77886f99c229610abd28c4c370d2c7d1536c9782
ToppCell	Control-Endothelial-Endothelial-Gen_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HECW2 RAPGEF4 GPCPD1 FAM135A NRP1	3.83e-05	193	87	5	e1d546165dcc2392f540162206852c4717d7306f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SYTL2 KSR2 FAM135A FAM83B CCSER1	3.93e-05	194	87	5	46070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SYTL2 KSR2 FAM135A FAM83B CCSER1	3.93e-05	194	87	5	abacb6a8d7a9003f2f6c2be0305507f1c1c50347
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HECW2 KSR2 RAPGEF4 RYR2 CCSER1	4.33e-05	198	87	5	0ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HECW2 SYNE2 RAPGEF4 ADCY1 NRP1	4.43e-05	199	87	5	5d976d57872a8a25a11fe8cd53b01aa21a1a519a
ToppCell	Macroglial-Polydendrocytes-PDGFRA-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	RAPGEF4 LRRK2 ASIC4 MYO16 CCSER1	4.54e-05	200	87	5	f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCell	Macroglial-Polydendrocytes-PDGFRA--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	RAPGEF4 LRRK2 ASIC4 MYO16 CCSER1	4.54e-05	200	87	5	cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCell	distal-Epithelial-Proliferating_Basal\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	AKR1B10 AKR1B15 FAM83D ADGRV1 FAM83B	4.54e-05	200	87	5	25cc494ef831511840d8c02ec1bd086635cc7edd
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	HECW2 KSR2 RAPGEF4 RYR2 CCSER1	4.54e-05	200	87	5	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	Macroglial-Polydendrocytes-PDGFRA\|Macroglial / cells hierarchy compared to all cells using T-Statistic	RAPGEF4 LRRK2 ASIC4 MYO16 CCSER1	4.54e-05	200	87	5	c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SYNE2 RAPGEF4 FAM135A NRP1 CCSER1	4.54e-05	200	87	5	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	distal-Epithelial-Proliferating_Basal-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	AKR1B10 AKR1B15 FAM83D ADGRV1 FAM83B	4.54e-05	200	87	5	cc31e8c28d01e6757c5dd7f485db6acf7409a47e
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-OPC_related-Oligodendrocyte/OPC\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	DNAH3 EVC2 ASPH TNKS1BP1 PHLDB2	4.54e-05	200	87	5	4db894cfb80fd1f9e01133f345eefd78edd4bc43
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-OPC_related\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	DNAH3 EVC2 ASPH TNKS1BP1 PHLDB2	4.54e-05	200	87	5	d46a19274c2836ce7494790ce513764dedcadc79
ToppCell	Macroglial-Polydendrocytes-PDGFRA---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	RAPGEF4 LRRK2 ASIC4 MYO16 CCSER1	4.54e-05	200	87	5	4fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCell	Macroglial-Polydendrocytes-PDGFRA----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	RAPGEF4 LRRK2 ASIC4 MYO16 CCSER1	4.54e-05	200	87	5	310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCell	Macroglial-Polydendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	RAPGEF4 LRRK2 ASIC4 MYO16 CCSER1	4.54e-05	200	87	5	961858738ce35db8760c8c2e136f8369bc444ccf
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NRBP2 ASIC4 CCDC38 PHLDB2	6.00e-05	108	87	4	d620f07243c2628494e689bbfabc14c453f4b1f4
Disease	symmetrical dimethylarginine measurement	AKR1B10 AKR1B15	2.91e-04	9	85	2	EFO_0006523
Disease	theophylline measurement	LRRK2 CCSER1	3.64e-04	10	85	2	EFO_0021180
Disease	Childhood Ataxia with Central Nervous System Hypomyelinization	EIF2B3 SCP2	7.30e-04	14	85	2	C1858991
Disease	cathepsin L1 measurement	LRRK2 IFI30	9.59e-04	16	85	2	EFO_0010619
Disease	intellectual disability (implicated_via_orthology)	RB1 POGZ GPRASP2	1.34e-03	75	85	3	DOID:1059 (implicated_via_orthology)
Disease	longitudinal BMI measurement	EVC2 MIGA2 KSR2	1.73e-03	82	85	3	EFO_0005937
Disease	proprotein convertase subtilisin/kexin type 9 measurement	TDRD15 KSR2	1.82e-03	22	85	2	EFO_0009312
Disease	colorectal health	ADGRV1 RYR2 NRP1 CCSER1	2.75e-03	201	85	4	EFO_0008460

Protein segments in the cluster

Peptide	Gene	Start	Entry
DDFLGSLMIDLIEVE	ESYT2	466	A0FGR8
IFDFSLTEEEMKDIE	AKR1D1	286	P51857
FPEMDESFLISLLEV	ADGRV1	2531	Q8WXG9
NFVIIYELLDELMDF	AP1M1	106	Q9BXS5
VFDFKLSDEEMATIL	AKR1B10	276	O60218
FAADLAEELVFEGIM	AKAP11	646	Q9UKA4
FLLMEQELTADEDIS	DOP1A	2251	Q5JWR5
FMLYVALESEDDTLA	ANGPTL5	241	Q86XS5
FLMATDVDDRFETLE	ASPH	186	Q12797
SCELDEDDLMLDLEF	CCSER1	511	Q9C0I3
EDDLMLDLEFLEEQS	CCSER1	516	Q9C0I3
EEEEFMKEFILTDIL	CC2D2B	136	Q6DHV5
TDFLEDLDFSEAMDL	CDR1	61	P51861
MALLEDVDLLEDTDF	CDR1	91	P51861
LAHALEADMELEFLE	ATP8B2	781	P98198
EASEFEMILDAAIEA	NWD2	136	Q9ULI1
AAVDLDEMSFTFTEL	RB1	106	P06400
FMEIDDIVRASEFLS	RAD17	461	O75943
EFTEADEAMAELAIA	NUP205	351	Q92621
LEFREDDVFLTELMK	ANKFY1	126	Q9P2R3
SDADLVMLLSLFEEE	HECW2	1131	Q9P2P5
IDDMQVFRILDLEDF	DAAM2	626	Q86T65
VFRILDLEDFEKMFS	DAAM2	631	Q86T65
EIFFEDELVCILNME	FBXO21	141	O94952
SEVSFMELDKFLEDV	NRBP2	361	Q9NSY0
EVEMEDLASFDEDLA	MCM5	71	P33992
ASDIAASEFIEEMLL	MYO16	291	Q9Y6X6
EESEDDFEEMNLSLL	KSR2	626	Q6VAB6
MEDSEFLAYVELLDE	EXD1	1	Q8NHP7
DIELESLEDFEHFLM	DCAF8L2	81	P0C7V8
ALVMDIFTDVDIFKE	FAM83B	151	Q5T0W9
EETLEEMNFLLSLDL	FAM135A	101	Q9P2D6
LEFMEELLETLITTE	DNAH8	3971	Q96JB1
VMDVFTDIDIFRDLQ	FAM83D	166	Q9H4H8
VLEDLLENMEADTFA	EVC2	1101	Q86UK5
LILDEESDIFMLIFD	LRRK2	151	Q5S007
DIVLDFILMDAFEDL	MIGA2	431	Q7L4E1
MDVFTDVEIFCDILE	FAM83A	166	Q86UY5
MEAPLVSLDEEFEDL	FEZ1	1	Q99689
LDVFFEALTSEAMEQ	ASIC4	416	Q96FT7
DREDDLIIEFDNMFS	HUWE1	2486	Q7Z6Z7
IDLLEKIAEDMNFDF	GRIN3A	581	Q8TCU5
EMEEENATLLTEFVL	OR5H6	16	Q8NGV6
KMSEIILEFESFDLE	NRP1	181	O14786
PSLDMFAEELAEEEL	CD2BP2	246	O95400
EELDVMFSELVDELD	DAAM1	51	Q9Y4D1
HLDFFEMLRNEDELE	DAAM1	331	Q9Y4D1
RLLFMANEADLDEEL	EIF2B3	166	Q9NR50
EDFIIDTLELRSDMY	EXOSC10	336	Q01780
LADFAIEMFDVLDEI	ADCY1	951	Q08828
EELLFDDGDDIMATL	FBF1	201	Q8TES7
TMEPDNLELIFDFFE	GPCPD1	221	Q9NPB8
DASERLEFLMDYADL	DNAH3	746	Q8TD57
ACVLDELDMELAFLT	IFI30	131	P13284
NISLVFDFMETDLEV	CDK7	86	P50613
AADLEIFLDTLRSME	CRYBG2	761	Q8N1P7
DVDREFVIMFTLVDE	HEPHL1	221	Q6MZM0
DSLEFLLDDEMDVDL	CCDC38	316	Q502W7
VAELPDEFFEEDNML	GET3	111	O43681
DMFTDVDLLSEVLEA	FAM83H	156	Q6ZRV2
GDMSEAELLILDEFT	RYR2	3346	Q92736
LAFAEEVMDDILDSA	POLRMT	861	O00411
LESEFMETLSDEEVL	PAOX	386	Q6QHF9
DDISDIFRFLDDMSI	MINAR1	516	Q9UPX6
DMFTDVDIFKDLLDA	FAM83G	181	A6ND36
DVVLDFILMDSFEDL	MIGA1	466	Q8NAN2
LFIDEVHMLDIESFS	RUVBL2	296	Q9Y230
MIDLSFLTEEEQEAI	SYTL2	1	Q9HCH5
LLQEDDVSMAFLEEF	RAPGEF4	591	Q8WZA2
MDLEDLSIIFETDEL	SYNE2	3846	Q8WXH0
DGDSFRLIVEMLEEF	TDRD15	186	B5MCY1
MDVFTDPDLLLDLVD	FAM83E	161	Q2M2I3
IESLEFLDEMELLEQ	LCMT1	296	Q9UIC8
EEMLLQIADDFIESV	TAF12	81	Q16514
EEFEEFLLLMDKIRD	GPRASP2	596	Q96D09
MIVAIDEISLFLDTE	POGZ	1121	Q7Z3K3
DLSTLVEDFFVMKEE	GPAM	501	Q9HCL2
DMDREFALLFLIFDE	HEPH	916	Q9BQS7
MVAACLLLFLEEEDA	SGSM3	206	Q96HU1
LQLSDEESVFEEALM	PHLDB2	486	Q86SQ0
LDEVMASKEVFDFLT	SCP2	206	P22307
ADLFLDMESVASLEL	URB1	986	O60287
VFDFKLSDEEMATIL	AKR1B15	276	C9JRZ8
FSVVLVDFESEDMDV	B4GALNT4	856	Q76KP1
FDDLLAAFDIPDMVD	ZNF532	11	Q9HCE3
EMLDDFDFDRLLDAA	UBN2	401	Q6ZU65
MDSVVFEDVAVDFTL	ZNF555	1	Q8NEP9
ALVSDLDLDFETFLM	MIPEP	696	Q99797
DFSFIEDTEILDSAM	TNKS1BP1	1556	Q9C0C2
LMLPESFSEEDLFIE	TAMM41	166	Q96BW9
MDSVVFEDVAVDFTL	ZNF57	1	Q68EA5