Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF492 ZBTB16 GCM2 ZNF280D ZNF473 ZBTB48 EBF3 ZNF268 ZNF175 SHOX ZBTB12 ZNF57 EBF1 ZNF317 ZNF71 EBF2 ZNF7 RLF ZNF677 ZNF16 ZNF26 SALL2 ZNF852 ZNF257 ZNF197 ZFHX2 ZNF264 ZNF81 ZNF841 ZNF98 PRDM15 ZNF415 NOTCH1 EBF4 ZNF572 ZNF554 ZNF646	2.13e-12	1412	142	37	GO:0000981
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF492 ZBTB16 GCM2 ZNF280D ZNF473 ZBTB48 EBF3 ZNF268 ZNF175 ZBTB12 EBF1 ZNF317 ZNF71 EBF2 ZNF7 ZNF677 ZNF16 ZNF26 SALL2 ZNF852 ZNF257 ZNF197 ZFHX2 ZNF264 ZNF81 ZNF841 ZNF98 PRDM15 ZNF415 NOTCH1 EBF4 ZNF572 ZNF646	5.59e-11	1271	142	33	GO:0000987
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF492 ZBTB16 GCM2 ZNF280D ZNF473 ZBTB48 EBF3 ZNF268 ZNF175 ZBTB12 ZNF57 EBF1 ZNF317 ZNF71 EBF2 ZNF7 ZNF677 ZNF16 STOX2 ZNF26 SALL2 ZNF852 ZNF257 ZNF197 ZFHX2 ZNF264 ZNF81 ZNF841 ZNF98 PRDM15 ZNF415 EBF4 ZNF572 ZNF554 ZNF646	1.12e-10	1459	142	35	GO:0000977
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF492 ZBTB16 GCM2 ZNF280D ZNF473 ZBTB48 EBF3 ZNF268 ZNF175 ZBTB12 EBF1 ZNF317 ZNF71 EBF2 ZNF7 ZNF677 ZNF16 ZNF26 SALL2 ZNF852 ZNF257 ZNF197 ZFHX2 ZNF264 ZNF81 ZNF841 ZNF98 PRDM15 ZNF415 EBF4 ZNF572 ZNF646	1.48e-10	1244	142	32	GO:0000978
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	ZBTB16 GCM2 ZNF473 EBF3 ZNF268 ZNF175 SHOX EBF1 ZNF71 EBF2 RLF SALL2 ZNF197 ZNF841 PRDM15 NOTCH1 EBF4	5.07e-07	560	142	17	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	ZBTB16 GCM2 ZNF473 EBF3 ZNF268 ZNF175 SHOX EBF1 ZNF71 EBF2 RLF SALL2 ZNF197 ZNF841 PRDM15 NOTCH1 EBF4	5.88e-07	566	142	17	GO:0001216
GeneOntologyMolecularFunction	amino acid binding	UBR2 SLC38A9 CASR NOS2 HDC	1.73e-04	73	142	5	GO:0016597
GeneOntologyMolecularFunction	translation elongation factor activity	EFL1 EEF1G EEF2	3.67e-04	20	142	3	GO:0003746
GeneOntologyBiologicalProcess	cell division	PDS5B KNTC1 ZBTB16 TENT4B SPTBN1 BCAR1 SMC2 USP16 SPAG5 ZNF16 ANAPC10 DOCK7 SEPTIN7 TRIM36 PRDM15 NOTCH1 KNL1	4.73e-06	697	139	17	GO:0051301
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	TET2 ZBTB16 GCM2 ZNF473 EBF3 ZNF268 ZNF175 MAML1 SHOX EBF1 USP16 ZNF71 EBF2 RLF MET SALL2 ZNF197 CAPRIN2 ZNF841 MED17 PRDM15 NOTCH1 EBF4 ZNF646	1.83e-05	1390	139	24	GO:0045944
GeneOntologyBiologicalProcess	positive regulation of mast cell activation	CFTR CRLF2 CD300LB	2.44e-05	9	139	3	GO:0033005
GeneOntologyBiologicalProcess	axo-dendritic protein transport	MYO5A KIF5B KIF5C	4.75e-05	11	139	3	GO:0099640
GeneOntologyCellularComponent	MAML1-RBP-Jkappa- ICN1 complex	MAML1 NOTCH1	1.39e-04	3	143	2	GO:0002193
GeneOntologyCellularComponent	ciliary rootlet	SPAG5 KIF5B KIF5C	1.64e-04	16	143	3	GO:0035253
HumanPheno	Splanchnic vein thrombosis	TET2 CFTR CASR MET NOTCH1	2.77e-06	25	48	5	HP:0030247
Domain	ZINC_FINGER_C2H2_2	ZNF492 ZBTB16 ZNF280D ZNF473 ZBTB48 ZNF268 ZNF175 RBM10 ZBTB12 ZNF57 ZNF317 ZNF804A ZNF71 ZNF7 RLF ZNF677 ZNF16 ZNF26 SALL2 ZNF852 ZNF257 ZNF197 ZFHX2 ZNF264 ZNF81 ZNF841 ZNF98 PRDM15 ZNF415 ZNF572 ZNF554 ZNF646	2.18e-15	775	141	32	PS50157
Domain	Znf_C2H2-like	ZNF492 ZBTB16 ZNF280D ZNF473 ZBTB48 ZNF268 ZNF175 RBM10 ZBTB12 ZNF57 ZNF317 ZNF804A ZNF71 ZNF7 RLF ZNF677 ZNF16 ZNF26 SALL2 ZNF852 ZNF257 ZNF197 ZFHX2 ZNF264 ZNF81 ZNF841 ZNF98 PRDM15 ZNF415 ZNF572 ZNF554 ZNF646	4.60e-15	796	141	32	IPR015880
Domain	zf-C2H2	ZNF492 ZBTB16 ZNF280D ZNF473 ZBTB48 ZNF268 ZNF175 ZBTB12 ZNF57 ZNF317 ZNF71 ZNF7 RLF ZNF677 ZNF16 ZNF26 SALL2 ZNF852 ZNF257 ZNF197 ZFHX2 ZNF264 ZNF81 ZNF841 ZNF98 PRDM15 ZNF415 ZNF572 ZNF554 ZNF646	5.44e-15	693	141	30	PF00096
Domain	Znf_C2H2	ZNF492 ZBTB16 ZNF280D ZNF473 ZBTB48 ZNF268 ZNF175 RBM10 ZBTB12 ZNF57 ZNF317 ZNF804A ZNF71 ZNF7 RLF ZNF677 ZNF16 ZNF26 SALL2 ZNF852 ZNF257 ZNF197 ZFHX2 ZNF264 ZNF81 ZNF841 ZNF98 PRDM15 ZNF415 ZNF572 ZNF554 ZNF646	6.30e-15	805	141	32	IPR007087
Domain	ZnF_C2H2	ZNF492 ZBTB16 ZNF280D ZNF473 ZBTB48 ZNF268 ZNF175 RBM10 ZBTB12 ZNF57 ZNF317 ZNF804A ZNF71 ZNF7 RLF ZNF677 ZNF16 ZNF26 SALL2 ZNF852 ZNF257 ZNF197 ZFHX2 ZNF264 ZNF81 ZNF841 ZNF98 PRDM15 ZNF415 ZNF572 ZNF554 ZNF646	6.99e-15	808	141	32	SM00355
Domain	ZINC_FINGER_C2H2_1	ZNF492 ZBTB16 ZNF280D ZNF473 ZBTB48 ZNF268 ZNF175 ZBTB12 ZNF57 ZNF317 ZNF804A ZNF71 ZNF7 RLF ZNF677 ZNF16 ZNF26 SALL2 ZNF852 ZNF257 ZNF197 ZFHX2 ZNF264 ZNF81 ZNF841 ZNF98 PRDM15 ZNF415 ZNF572 ZNF554 ZNF646	1.63e-14	777	141	31	PS00028
Domain	-	ZNF492 ZBTB16 ZNF473 ZBTB48 ZNF268 ZNF175 ZBTB12 ZNF57 ZNF317 ZNF71 ZNF7 RLF ZNF677 ZNF16 ZNF26 SALL2 ZNF852 ZNF257 ZNF197 ZFHX2 ZNF264 ZNF81 ZNF841 ZNF98 PRDM15 ZNF415 ZNF572 ZNF554 ZNF646	2.35e-14	679	141	29	3.30.160.60
Domain	Znf_C2H2/integrase_DNA-bd	ZNF492 ZBTB16 ZNF473 ZBTB48 ZNF268 ZNF175 ZBTB12 ZNF57 ZNF317 ZNF71 ZNF7 RLF ZNF677 ZNF16 ZNF26 SALL2 ZNF852 ZNF257 ZNF197 ZFHX2 ZNF264 ZNF81 ZNF841 ZNF98 PRDM15 ZNF415 ZNF572 ZNF554 ZNF646	4.10e-14	694	141	29	IPR013087
Domain	zf-C2H2_6	ZNF492 ZBTB16 ZNF473 ZBTB48 ZNF317 ZNF71 ZNF677 ZNF16 ZNF26 SALL2 ZNF852 ZNF197 ZNF841 ZNF98 ZNF572 ZNF554 ZNF646	2.40e-10	314	141	17	PF13912
Domain	COE	EBF3 EBF1 EBF2 EBF4	3.11e-09	4	141	4	PS01345
Domain	Transcription_factor_COE	EBF3 EBF1 EBF2 EBF4	3.11e-09	4	141	4	IPR003523
Domain	COE_HLH	EBF3 EBF1 EBF2 EBF4	3.11e-09	4	141	4	IPR032201
Domain	COE_DBD	EBF3 EBF1 EBF2 EBF4	3.11e-09	4	141	4	IPR032200
Domain	Transcription_factor_COE_CS	EBF3 EBF1 EBF2 EBF4	3.11e-09	4	141	4	IPR018350
Domain	COE1_HLH	EBF3 EBF1 EBF2 EBF4	3.11e-09	4	141	4	PF16423
Domain	COE1_DBD	EBF3 EBF1 EBF2 EBF4	3.11e-09	4	141	4	PF16422
Domain	KRAB	ZNF492 ZNF473 ZNF268 ZNF175 ZNF57 ZNF317 ZNF7 ZNF677 ZNF26 ZNF852 ZNF257 ZNF197 ZNF264 ZNF81 ZNF98 ZNF554	1.30e-08	358	141	16	PS50805
Domain	KRAB	ZNF492 ZNF473 ZNF268 ZNF175 ZNF57 ZNF317 ZNF7 ZNF677 ZNF26 ZNF852 ZNF257 ZNF197 ZNF264 ZNF81 ZNF98 ZNF554	1.30e-08	358	141	16	PF01352
Domain	KRAB	ZNF492 ZNF473 ZNF268 ZNF175 ZNF57 ZNF317 ZNF7 ZNF677 ZNF26 ZNF852 ZNF257 ZNF197 ZNF264 ZNF81 ZNF98 ZNF554	1.99e-08	369	141	16	SM00349
Domain	KRAB	ZNF492 ZNF473 ZNF268 ZNF175 ZNF57 ZNF317 ZNF7 ZNF677 ZNF26 ZNF852 ZNF257 ZNF197 ZNF264 ZNF81 ZNF98 ZNF554	2.07e-08	370	141	16	IPR001909
Domain	IPT	EBF3 EBF1 EBF2 MET EBF4	1.61e-06	27	141	5	SM00429
Domain	TIG	EBF3 EBF1 EBF2 MET EBF4	3.31e-06	31	141	5	PF01833
Domain	IPT	EBF3 EBF1 EBF2 MET EBF4	3.90e-06	32	141	5	IPR002909
Domain	Ig_E-set	EBF3 EBF1 EBF2 MET TGM7 EBF4	1.38e-04	104	141	6	IPR014756
Domain	EFG_II	EFL1 EEF2	5.58e-04	5	141	2	PF14492
Domain	EFG_C	EFL1 EEF2	8.32e-04	6	141	2	PF00679
Domain	EFG_III-V	EFL1 EEF2	8.32e-04	6	141	2	IPR009022
Domain	EFG_C	EFL1 EEF2	8.32e-04	6	141	2	SM00838
Domain	-	EFL1 EEF2	1.16e-03	7	141	2	3.30.70.240
Domain	EFG_V	EFL1 EEF2	1.16e-03	7	141	2	IPR000640
Pubmed	Cloning of a novel Olf-1/EBF-like gene, O/E-4, by degenerate oligo-based direct selection.	EBF3 EBF1 EBF2 EBF4	2.74e-10	4	143	4	12139918
Pubmed	Expression patterns of the coe/ebf transcription factor genes during chicken and mouse limb development.	EBF3 EBF1 EBF2 EBF4	1.37e-09	5	143	4	15261831
Pubmed	Ebf factors and MyoD cooperate to regulate muscle relaxation via Atp2a1.	EBF3 EBF1 EBF2 EBF4	9.50e-09	7	143	4	24786561
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF57 ZNF317 ZNF7 ZNF257 ZNF197 ZNF264 ZNF841 ZNF98 ZNF554	6.72e-08	181	143	9	37372979
Pubmed	The characterization of the Olf-1/EBF-like HLH transcription factor family: implications in olfactory gene regulation and neuronal development.	EBF3 EBF1 EBF2	6.81e-08	3	143	3	9151732
Pubmed	An ancient role for collier/Olf/Ebf (COE)-type transcription factors in axial motor neuron development.	EBF3 EBF1 EBF2 EBF4	1.32e-07	12	143	4	30658714
Pubmed	Transient and lineage-restricted requirement of Ebf3 for sternum ossification.	EBF3 EBF1 EBF2 EBF4	1.32e-07	12	143	4	32398354
Pubmed	Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	TET2 ZNF280D ZNF317 EPG5 RAVER2 DNAH5 KNL1	2.13e-07	101	143	7	10997877
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	SPTBN1 PTPN23 SMC2 EEF1G EEF2 AHNAK DHCR7 RAB3GAP2 DOCK7 KIF5B SEPTIN7 MED17 RPL5 NOTCH1 SDHA	2.54e-07	708	143	15	39231216
Pubmed	Cloning and functional characterization of Roaz, a zinc finger protein that interacts with O/E-1 to regulate gene expression: implications for olfactory neuronal development.	EBF3 EBF1 EBF2	2.71e-07	4	143	3	9151733
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	TET2 ZNF473 MYO5A CNST SPTBN1 DNAAF9 USP16 BRWD3 ZNF7 MAGI2 UBE4A EEF2 ZNF197 LRP1 ZNF841 KIF5C SEPTIN7 WDR13 TARBP1 SDHA	3.38e-07	1285	143	20	35914814
Pubmed	Formation of whisker-related principal sensory nucleus-based lemniscal pathway requires a paired homeodomain transcription factor, Drg11.	EBF3 EBF1 EBF2	6.77e-07	5	143	3	12917357
Pubmed	Family of Ebf/Olf-1-related genes potentially involved in neuronal differentiation and regional specification in the central nervous system.	EBF3 EBF1 EBF2	1.35e-06	6	143	3	9389446
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TET2 ZNF280D LIN9 SPAG5 RLF SALL2 AHNAK RAB3GAP2 DOCK7 LRP1 KNL1	1.39e-06	418	143	11	34709266
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	VMP1 PDS5B TENT4B ZNF473 SPTBN1 ZNF317 RLF UBE4A ZNF16 EEF1G EEF2 AHNAK DHCR7 DOCK7 LRP1 RPL5 AMIGO2 ZNF646	2.39e-06	1203	143	18	29180619
Pubmed	Early B-cell factors are required for specifying multiple retinal cell types and subtypes from postmitotic precursors.	EBF3 EBF1 EBF2 EBF4	2.73e-06	24	143	4	20826655
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	TET2 PDS5B KNTC1 ARHGAP15 EBF3 RBM10 MAML1 SMC2 LIN9 RLF EEF1G EEF2 RAB3GAP2 KIF5B MED17 RPL5 KNL1	3.15e-06	1103	143	17	34189442
Pubmed	Genetic disruptions of O/E2 and O/E3 genes reveal involvement in olfactory receptor neuron projection.	EBF3 EBF1 EBF2	3.75e-06	8	143	3	14993187
Pubmed	Asparaginyl hydroxylation of the Notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor.	MAML1 CASR NOTCH1	5.61e-06	9	143	3	17573339
Pubmed	EBF2 determines and maintains brown adipocyte identity.	EBF3 EBF1 EBF2 EBF4	6.01e-06	29	143	4	23499423
Pubmed	Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development.	HTR4 CNST AARSD1 PRKCQ TRIM36 EBF4 AMIGO2	6.03e-06	166	143	7	19906978
Pubmed	Control of hindbrain motor neuron differentiation by the homeobox gene Phox2b.	EBF3 EBF1 EBF2	1.10e-05	11	143	3	10704382
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	UBR2 EBF3 ZNF268 MAML1 SMC2 LIN9 NDUFV2 UBE4A SALL2 LRP1 KIF5B PRDM15 NOTCH1 ARMC6	1.29e-05	857	143	14	25609649
Pubmed	Faciogenital Dysplasia 5 supports cancer stem cell traits in basal-like breast cancer by enhancing EGFR stability.	MET EEF1G AHNAK DOCK7 KIF5B SEPTIN7 SDHA	1.50e-05	191	143	7	33762435
Pubmed	Inducible nitric oxide synthase expression is reduced in cystic fibrosis murine and human airway epithelial cells.	CFTR NOS2	1.68e-05	2	143	2	9739054
Pubmed	Structural and mechanistic insights into cooperative assembly of dimeric Notch transcription complexes.	MAML1 NOTCH1	1.68e-05	2	143	2	20972443
Pubmed	Expression and chromosome localization of the murine cystic fibrosis transmembrane conductance regulator.	CFTR MET	1.68e-05	2	143	2	1377165
Pubmed	Early B Cell Factor Activity Controls Developmental and Adaptive Thermogenic Gene Programming in Adipocytes.	EBF1 EBF2	1.68e-05	2	143	2	32130892
Pubmed	Coexpression of c-Met and Notch-1 correlates with poor prognosis in resected non-small-cell lung cancer.	MET NOTCH1	1.68e-05	2	143	2	25869878
Pubmed	The testis anion transporter TAT1 (SLC26A8) physically and functionally interacts with the cystic fibrosis transmembrane conductance regulator channel: a potential role during sperm capacitation.	CFTR SLC26A8	1.68e-05	2	143	2	22121115
Pubmed	Inducible nitric oxide synthase up-regulates Notch-1 in mouse cholangiocytes: implications for carcinogenesis.	NOS2 NOTCH1	1.68e-05	2	143	2	15887117
Pubmed	Critical role for Ebf1 and Ebf2 in the adipogenic transcriptional cascade.	EBF1 EBF2	1.68e-05	2	143	2	17060461
Pubmed	Regulation of pre-natal circle of Willis assembly by vascular smooth muscle Notch signaling.	MAML1 NOTCH1	1.68e-05	2	143	2	23769842
Pubmed	Rescue of the skeletal phenotype in CasR-deficient mice by transfer onto the Gcm2 null background.	GCM2 CASR	1.68e-05	2	143	2	12671052
Pubmed	The hunting of the snark: the elusive calcium receptor(s).	GCM2 CASR	1.68e-05	2	143	2	12671040
Pubmed	Glial cells missing-2 (GCM2) transactivates the calcium-sensing receptor gene: effect of a dominant-negative GCM2 mutant associated with autosomal dominant hypoparathyroidism.	GCM2 CASR	1.68e-05	2	143	2	18712808
Pubmed	Altered Met receptor phosphorylation and LRP1-mediated uptake in cells lacking carbohydrate-dependent lysosomal targeting.	MET LRP1	1.68e-05	2	143	2	28724630
Pubmed	Calcium-sensing receptor expression is regulated by glial cells missing-2 in human parathyroid cells.	GCM2 CASR	1.68e-05	2	143	2	19257819
Pubmed	LoVo colon cancer cells resistant to oxaliplatin overexpress c-MET and VEGFR-1 and respond to VEGF with dephosphorylation of c-MET.	FLT1 MET	1.68e-05	2	143	2	25647613
Pubmed	Calcium-sensing receptor abrogates secretagogue- induced increases in intestinal net fluid secretion by enhancing cyclic nucleotide destruction.	GCM2 CASR	1.68e-05	2	143	2	16760252
Pubmed	CRLF2 expression associates with ICN1 stabilization in T-cell acute lymphoblastic leukemia.	CRLF2 NOTCH1	1.68e-05	2	143	2	30578688
Pubmed	The extracellular calcium-sensing receptor regulates human fetal lung development via CFTR.	CFTR CASR	1.68e-05	2	143	2	26911344
Pubmed	Meta-analysis of IDH-mutant cancers identifies EBF1 as an interaction partner for TET2.	TET2 EBF1	1.68e-05	2	143	2	23863747
Pubmed	Control of the migratory pathway of facial branchiomotor neurones.	EBF3 EBF1 EBF2	1.89e-05	13	143	3	11076752
Pubmed	Early B-cell factors 2 and 3 (EBF2/3) regulate early migration of Cajal-Retzius cells from the cortical hem.	EBF3 EBF1 EBF2	1.89e-05	13	143	3	22421355
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	MYO5A CNST SPTBN1 NDUFV2 MAGI2 MET EEF1G DHCR7 RAB3GAP2 CNTNAP2 DOCK7 KIF5B SEPTIN7 RPL5 SDHA ARMC6	1.96e-05	1139	143	16	36417873
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	PDS5B KNTC1 ATG10 EBF3 SMC2 MAGI2 MET UBE4A TTBK1 DHCR7 RAB3GAP2 DHPS DDX20 KIF5B KIF5C SEPTIN7 ARMC6	2.26e-05	1284	143	17	17353931
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	PDS5B KNTC1 TENT4B ZNF280D SPTBN1 SMC2 UBE4A EEF1G EEF2 DHCR7 RAB3GAP2 DOCK7 DDX20 KIF5B SEPTIN7 DNAH5 RPL5 SDHA	2.38e-05	1425	143	18	30948266
Pubmed	A census of human transcription factors: function, expression and evolution.	GCM2 ZBTB48 EBF3 ZNF268 ZNF175 SHOX EBF1 ZNF7 ZNF16 ZNF26 SALL2 ZNF197 ZFHX2 EBF4	2.45e-05	908	143	14	19274049
Pubmed	Quantitative analysis of PPT1 interactome in human neuroblastoma cells.	SPTBN1 EEF1G EEF2 AHNAK DOCK7 KIF5C SEPTIN7	2.76e-05	210	143	7	26217791
Pubmed	Ebf2 is required for development of dopamine neurons in the midbrain periaqueductal gray matter of mouse.	EBF3 EBF1 EBF2	2.99e-05	15	143	3	25762221
Pubmed	Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling.	MYO5A SPTBN1 EEF1G DOCK7 KIF5B KIF5C	3.42e-05	147	143	6	16959763
Pubmed	Periaxin is required for hexagonal geometry and membrane organization of mature lens fibers.	SPTBN1 AHNAK CNTNAP2	3.66e-05	16	143	3	21745462
Pubmed	Linkage analyses using biochemical variants in mice. 3. Linkage relationships of eleven biochemical markers.	ZBTB16 MYO5A DOCK7	3.66e-05	16	143	3	5424503
Pubmed	Deltex3 inhibits Epithelial Mesenchymal Transition in Papillary Thyroid Carcinoma via promoting ubiquitination of XRCC5 to regulate the AKT signal pathway.	MYO5A SPTBN1 EEF2 AHNAK	3.91e-05	46	143	4	33403043
Pubmed	The Transcription Factors EBF1 and EBF2 Are Positive Regulators of Myelination in Schwann Cells.	EBF3 EBF1 EBF2	4.44e-05	17	143	3	27889898
Pubmed	Self-organization of MTOCs replaces centrosome function during acentrosomal spindle assembly in live mouse oocytes.	KIF5B KIF5C	5.02e-05	3	143	2	17693257
Pubmed	Absence of annulus in human asthenozoospermia: case report.	SLC26A8 SEPTIN7	5.02e-05	3	143	2	19221096
Pubmed	Reactive Neutrophil Responses Dependent on the Receptor Tyrosine Kinase c-MET Limit Cancer Immunotherapy.	MET NOS2	5.02e-05	3	143	2	29045907
Pubmed	A human protein with sequence similarity to Drosophila mastermind coordinates the nuclear form of notch and a CSL protein to build a transcriptional activator complex on target promoters.	MAML1 NOTCH1	5.02e-05	3	143	2	11390662
Pubmed	ZBP-89 negatively regulates self-renewal of liver cancer stem cells via suppression of Notch1 signaling pathway.	MAML1 NOTCH1	5.02e-05	3	143	2	31874246
Pubmed	Notch activation induces endothelial cell senescence and pro-inflammatory response: implication of Notch signaling in atherosclerosis.	MAML1 NOTCH1	5.02e-05	3	143	2	23078884
Pubmed	Mastermind-like transcriptional co-activator-mediated Notch signaling is indispensable for maintaining conjunctival epithelial identity.	MAML1 NOTCH1	5.02e-05	3	143	2	23293291
Pubmed	Cloning and localization of a conventional kinesin motor expressed exclusively in neurons.	KIF5B KIF5C	5.02e-05	3	143	2	7514426
Pubmed	Direct inhibition of the NOTCH transcription factor complex.	MAML1 NOTCH1	5.02e-05	3	143	2	19907488
Pubmed	Genetic and clinical characteristics of korean patients with isolated hypoparathyroidism: from the Korean hypopara registry study.	GCM2 CASR	5.02e-05	3	143	2	24133354
Pubmed	Notch signaling mediates hypoxia-induced tumor cell migration and invasion.	MAML1 NOTCH1	5.02e-05	3	143	2	18427106
Pubmed	Mutational and energetic studies of Notch 1 transcription complexes.	MAML1 NOTCH1	5.02e-05	3	143	2	18155729
Pubmed	Olfactory Sensory Neurons Control Dendritic Complexity of Mitral Cells via Notch Signaling.	MAML1 NOTCH1	5.02e-05	3	143	2	28027303
Pubmed	Mastermind critically regulates Notch-mediated lymphoid cell fate decisions.	MAML1 NOTCH1	5.02e-05	3	143	2	15187027
Pubmed	Structural requirements for assembly of the CSL.intracellular Notch1.Mastermind-like 1 transcriptional activation complex.	MAML1 NOTCH1	5.02e-05	3	143	2	12644465
Pubmed	Molecular mechanisms of calcium-sensing receptor-mediated calcium signaling in the modulation of epithelial ion transport and bicarbonate secretion.	CFTR CASR	5.02e-05	3	143	2	25331955
Pubmed	Growth factor receptor expression in anal squamous lesions: modifications associated with oncogenic human papillomavirus and human immunodeficiency virus.	FLT1 MET	5.02e-05	3	143	2	19716155
Pubmed	Kinesin-1 Proteins KIF5A, -5B, and -5C Promote Anterograde Transport of Herpes Simplex Virus Enveloped Virions in Axons.	KIF5B KIF5C	5.02e-05	3	143	2	30068641
Pubmed	Long non-coding RNA (lncRNA) MAGI2-AS3 inhibits breast cancer cell growth by targeting the Fas/FasL signalling pathway.	PDS5B MAGI2	5.02e-05	3	143	2	29679339
Pubmed	Angiogenesis-related protein expression in bevacizumab-treated metastatic colorectal cancer: NOTCH1 detrimental to overall survival.	FLT1 NOTCH1	5.02e-05	3	143	2	26394830
Pubmed	Endosomal sorting drives the formation of axonal prion protein endoggresomes.	KIF5B KIF5C	5.02e-05	3	143	2	34936461
Pubmed	Nitric oxide is involved in Mycobacterium bovis bacillus Calmette-Guérin-activated Jagged1 and Notch1 signaling.	NOS2 NOTCH1	5.02e-05	3	143	2	20147635
Pubmed	Age-Progressive and Gender-Dependent Bone Phenotype in Mice Lacking Both Ebf1 and Ebf2 in Prrx1-Expressing Mesenchymal Cells.	EBF1 EBF2	5.02e-05	3	143	2	35137272
Pubmed	Conformational locking upon cooperative assembly of notch transcription complexes.	MAML1 NOTCH1	5.02e-05	3	143	2	22325781
Pubmed	Snail inhibits Notch1 intracellular domain mediated transcriptional activation via competing with MAML1.	MAML1 NOTCH1	5.02e-05	3	143	2	23454378
Pubmed	LINKAGE OF THE MOUSE TRANSFERRIN LOCUS.	ZBTB16 MYO5A	5.02e-05	3	143	2	14051864
Pubmed	A new hepatocytic isoform of PLZF lacking the BTB domain interacts with ATP7B, the Wilson disease protein, and positively regulates ERK signal transduction.	ZBTB16 HP	5.02e-05	3	143	2	16676348
Pubmed	Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes.	MAML1 NOTCH1	5.02e-05	3	143	2	16530044
Pubmed	Correlation between HGF/c-Met and Notch1 signaling pathways in human gastric cancer cells.	MET NOTCH1	5.02e-05	3	143	2	29781036
Pubmed	p53 Modulates Notch Signaling in MCF-7 Breast Cancer Cells by Associating With the Notch Transcriptional Complex Via MAML1.	MAML1 NOTCH1	5.02e-05	3	143	2	26033683
Pubmed	Characterization of a high-molecular-weight Notch complex in the nucleus of Notch(ic)-transformed RKE cells and in a human T-cell leukemia cell line.	MAML1 NOTCH1	5.02e-05	3	143	2	11997524
Pubmed	The notch regulator MAML1 interacts with p53 and functions as a coactivator.	MAML1 NOTCH1	5.02e-05	3	143	2	17317671
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PDS5B UBR2 AVL9 RBM10 EPG5 MAGI2 SV2B RAB3GAP2 DOCK7	5.06e-05	407	143	9	12693553
Pubmed	Genome-wide association analysis demonstrates the highly polygenic character of age-related hearing impairment.	SV2B CNTNAP2 DEPDC5	5.31e-05	18	143	3	24939585
Pubmed	A key role for the HLH transcription factor EBF2COE2,O/E-3 in Purkinje neuron migration and cerebellar cortical topography.	EBF3 EBF1 EBF2	7.37e-05	20	143	3	16774995
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	MYO5A RBM10 SPTBN1 SMC2 EEF1G EEF2 SALL2 AHNAK RAB3GAP2 DOCK7 DDX20 KIF5B HCFC2 SEPTIN7 RPL5	8.25e-05	1149	143	15	35446349
Pubmed	Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.	EBF3 EBF1 EBF2 ZNF7 ZFHX2 NOTCH1 EBF4	8.52e-05	251	143	7	29031500
Pubmed	The Tbr2 Molecular Network Controls Cortical Neuronal Differentiation Through Complementary Genetic and Epigenetic Pathways.	EBF3 EBF1 EBF2	8.57e-05	21	143	3	27600842
Pubmed	Characterization and mapping of human genes encoding zinc finger proteins.	ZNF57 ZNF71 ZNF7	9.90e-05	22	143	3	1946370
Pubmed	Nemo-like kinase suppresses Notch signalling by interfering with formation of the Notch active transcriptional complex.	MAML1 NOTCH1	1.00e-04	4	143	2	20118921
Pubmed	Myosin5a tail associates directly with Rab3A-containing compartments in neurons.	MYO5A KIF5B	1.00e-04	4	143	2	21349835
Pubmed	Localization of the cystic fibrosis transmembrane conductance regulator (Cftr) to mouse chromosome 6.	CFTR MET	1.00e-04	4	143	2	1385049
Pubmed	GRIF-1 and OIP106, members of a novel gene family of coiled-coil domain proteins: association in vivo and in vitro with kinesin.	KIF5B KIF5C	1.00e-04	4	143	2	15644324
Pubmed	The killing of Leishmania major by human macrophages is mediated by nitric oxide induced after ligation of the Fc epsilon RII/CD23 surface antigen.	FCER2 NOS2	1.00e-04	4	143	2	7544003
Interaction	EBF4 interactions	EBF3 EBF1 EBF4	1.20e-05	7	143	3	int:EBF4
Interaction	TRIM28 interactions	PDS5B EFL1 ZNF492 ZNF268 CFTR PTPN23 ZNF57 ZNF317 SMC2 ZNF7 EEF1G ZNF26 ZNF257 RAB3GAP2 ZNF197 ZNF264 ZNF81 KIF5B ZNF841 KIF5C SPRTN ZNF98 DNAH5 RPL5 NOTCH1 ZNF554	1.35e-05	1474	143	26	int:TRIM28
Interaction	EBF3 interactions	EBF3 EBF2 MARF1 EBF4	1.61e-05	22	143	4	int:EBF3
Cytoband	8p21.2	ADAM7 SLC25A37 EBF2	6.47e-05	25	143	3	8p21.2
Cytoband	12p11	ITPR2 CAPRIN2	3.42e-04	9	143	2	12p11
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF492 ZBTB16 ZNF473 ZBTB48 ZNF268 ZNF175 ZBTB12 ZNF57 ZNF317 ZNF71 ZNF7 RLF ZNF677 ZNF16 ZNF26 SALL2 ZNF852 ZNF257 ZNF197 ZFHX2 ZNF264 ZNF81 ZNF841 ZNF98 PRDM15 ZNF415 ZNF572 ZNF554 ZNF646	1.57e-17	718	101	29	28
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EBF3 EBF1 EBF2 EEF2 AHNAK MLF1 SEPTIN7 RPL5 BICC1	1.73e-08	199	143	9	c007cd51577e31553395ceaed70ad447e5854546
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FLT1 ZBTB16 CNST SPTBN1 GIMAP8 RIN2 NOS2	1.27e-06	169	143	7	987ff79ad563825dd9877ea8ccb536758f8c6700
ToppCell	severe-B_naive\|severe / disease stage, cell group and cell class	ZBTB16 EBF1 IQCN EEF1G FCER2 CNTNAP2 RPL5	2.76e-06	190	143	7	2430a1fd18385305bf1b604747ff64026a8d5edf
ToppCell	LA-02._Fibroblast_II\|LA / Chamber and Cluster_Paper	ZBTB16 SPTBN1 EBF1 EBF2 LRP1 SSH2 BICC1	3.17e-06	194	143	7	234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCell	10x5'-lymph-node_spleen\|World / Manually curated celltypes from each tissue	ARHGAP15 EBF1 EEF1G EEF2 CD5 FCER2 SSH2	3.39e-06	196	143	7	2951be22ab9095c4d3286c69dc4ab3308287c145
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EBF3 SPTBN1 EBF1 EBF2 AHNAK MLF1 BICC1	3.75e-06	199	143	7	bfc157be6e9f84739848eb19b718de5b17f3fa88
ToppCell	Hematolymphoid-Endothelial-NOSTRIN\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	FLT1 NLRX1 SPTBN1 EBF1 MAGI2 STOX2 AHNAK	3.87e-06	200	143	7	032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCell	Hematolymphoid-Endothelial-NOSTRIN---\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	FLT1 NLRX1 SPTBN1 EBF1 MAGI2 STOX2 AHNAK	3.87e-06	200	143	7	68fce28690246895fd33354b30960ebcc31aa4cc
ToppCell	Hematolymphoid-Endothelial-NOSTRIN-\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	FLT1 NLRX1 SPTBN1 EBF1 MAGI2 STOX2 AHNAK	3.87e-06	200	143	7	376b19ab5a7cd2c85f726d8ba41337d4525863e5
ToppCell	Hematolymphoid-Endothelial-NOSTRIN--\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	FLT1 NLRX1 SPTBN1 EBF1 MAGI2 STOX2 AHNAK	3.87e-06	200	143	7	7fa54370221ed61bac0e09e6bcf1f3dff202a846
ToppCell	Hematolymphoid-Endothelial-NOSTRIN----L2-6\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	FLT1 NLRX1 SPTBN1 EBF1 MAGI2 STOX2 AHNAK	3.87e-06	200	143	7	878bbbe32e3602723aa14ef32877ab2453b8c6e5
ToppCell	Hematolymphoid-Endothelial\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	FLT1 NLRX1 SPTBN1 EBF1 MAGI2 STOX2 AHNAK	3.87e-06	200	143	7	7136936d05ab344a560cf159684c881063b5430d
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KNTC1 FLT1 EBF3 SPAG5 CD5 NOTCH1	4.18e-06	131	143	6	419a0a83b38eaea890d065c3f252ef83c2d37b5b
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-Klrb1a/b/c(-)_NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HTR4 AHNAK RAVER2 TGM7 PRKCQ HDC	1.57e-05	165	143	6	651d40eadb1b34de618af94c167f43635729d43f
ToppCell	COVID-CD8-exh_CD4\|COVID / Condition, Cell_class and T cell subcluster	PTPN23 ZNF57 LIN9 AARSD1 RLF SPRTN	1.62e-05	166	143	6	4ca8c91b03d08489f244898cf9423b9d10348bc8
ToppCell	Ionocyte-iono-3\|World / Class top	KNTC1 MYO5A CFTR PTPN23 ADCY7 GIMAP8	1.62e-05	166	143	6	9c4a780f8af46d7552077c7a0ae0ab1b2413e5d4
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ARHGAP15 SPTBN1 CD5 AHNAK PRKCQ KIF5C	1.68e-05	167	143	6	83969c36ac44b96afc9aa09400a99fa2b487f7ff
ToppCell	droplet-Marrow-BM_(NON-STC)\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMC2 SLC25A37 RHAG HP KIF5B KNL1	1.98e-05	172	143	6	6004327045f03d832fdabe6cb2f8b1b1db57789a
ToppCell	droplet-Marrow-BM_(NON-STC)-30m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMC2 SLC25A37 RHAG HP KIF5B KNL1	1.98e-05	172	143	6	31c5710fd7ebb221e703545595f5ec0ee3a32bcf
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARHGAP15 SMC2 SPAG5 CD5 PRKCQ KNL1	1.98e-05	172	143	6	282017db72d0537ac82aecc69393ccde9590be60
ToppCell	facs-Lung-nan-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP15 EBF2 ZNF7 CAPRIN2 PRKCQ KIF5C	2.11e-05	174	143	6	1c073177c1753e3b91ef8fd9e95230a1d13c82f3
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZNF492 HTR4 EBF3 EBF1 ITPR2 GIMAP8	2.11e-05	174	143	6	18ab52d8bbca0507fee220e0c4fc765fc47dda34
ToppCell	facs-Lung-nan-3m-Lymphocytic-CD8+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP15 EBF2 ZNF7 CAPRIN2 PRKCQ KIF5C	2.11e-05	174	143	6	5491ad5c144baf2ef9b1c58eb720c872d14feb15
ToppCell	droplet-Spleen-nan-3m-Lymphocytic-immature_NKT_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KNTC1 SMC2 CD5 MLF1 TARBP1 KNL1	2.48e-05	179	143	6	54621d2b3a66e62aa76b7e444118878ed97c1e02
ToppCell	Healthy_Control-Lymphoid-T-\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	KNTC1 SPTBN1 SMC2 SPAG5 HP KNL1	2.64e-05	181	143	6	ac1ee313910c05b1b3cb497bae14565464919c21
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-B\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ZBTB16 SHOX EEF2 DHPS RPL5 SDHA	2.81e-05	183	143	6	dc8220ac8879b118a4ef64ce6417d6d3874143ca
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	LIN9 BRWD3 UBE4A MARF1 KIF5B SPRTN	3.08e-05	186	143	6	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	COVID-19-Heart-Fib_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HTR4 EBF3 EBF1 EBF2 LRP1 BICC1	3.27e-05	188	143	6	fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCell	droplet-Lung-nan-21m-Lymphocytic-Proliferating_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KNTC1 SMC2 LIN9 CD5 MLF1 KNL1	3.27e-05	188	143	6	61ae7405ab56570409bf35382dc0a038e4137c15
ToppCell	droplet-Lung-1m-Hematologic-lymphocytic\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGAP15 EEF1G CD5 FCER2 PRKCQ RPL5	3.27e-05	188	143	6	3e0bc7c92b3946a03276dc8b6cffed5aa0681a8c
ToppCell	droplet-Mammary_Gland-nan-3m-Lymphocytic-T_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP15 EEF2 CD5 PRKCQ SSH2 RPL5	3.36e-05	189	143	6	e00938e90f0bb0bfe17b74ef601c09079e1c2b17
ToppCell	COVID-19-Heart-EC_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FLT1 EBF3 SPTBN1 EBF1 SV2B RIN2	3.36e-05	189	143	6	fe49852ba15f948b384d6b4c258927c70b741357
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CASR MET STOX2 PRKCQ DNAH5 BICC1	3.46e-05	190	143	6	3fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_EM-B\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	IQCN LIN9 ANAPC10 MED17 TEN1 PRDM15	3.46e-05	190	143	6	a8d92645950715d2621bf0064b1b2bb4eb400cb3
ToppCell	COVID-19-Heart-Mito_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FLT1 EBF3 EBF1 EBF2 EEF2 SV2B	3.46e-05	190	143	6	ea74e0e38bcaba125b48c88331e9ba09228d3178
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KNTC1 SMC2 LIN9 SPAG5 MLF1 KNL1	3.57e-05	191	143	6	15dbc5a03bfab8931c0fd385b0f25874736ae874
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN1 BRWD3 ITPR2 ANKIB1 KIF5B SEPTIN7	3.57e-05	191	143	6	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-Proliferating_T_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KNTC1 SMC2 LIN9 SPAG5 MLF1 KNL1	3.57e-05	191	143	6	45c15f5ce4a207ac944bed65d45f06c1657d1a6d
ToppCell	droplet-Mammary_Gland-nan-3m-Lymphocytic-T_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP15 EEF2 CD5 PRKCQ SSH2 RPL5	3.57e-05	191	143	6	7943049e935c09cbda6f60ab3f09c4424a5f9d43
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN1 BRWD3 ITPR2 ANKIB1 KIF5B SEPTIN7	3.57e-05	191	143	6	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FLT1 ZBTB16 SPTBN1 EBF1 GIMAP8 RIN2	3.78e-05	193	143	6	456aa8a8f1f9cbba0bd618a5f623909079c0f56b
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CASR MET STOX2 SSH2 DNAH5 BICC1	3.89e-05	194	143	6	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	3'_v3-blood-Lymphocytic_T_CD4-Teffector/EM_CD4\|blood / Manually curated celltypes from each tissue	ARHGAP15 EEF1G EEF2 CD5 KIF5C RPL5	3.89e-05	194	143	6	8499c03fa3d5cf9631b128681b13b7fc512b7e63
ToppCell	LPS-IL1RA-Unknown-Endothelial\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZNF317 SPAG5 SLC26A8 FCER2 NRXN2	3.96e-05	118	143	5	aefad0b35aff980b6a2a98057735442e8a65ab04
ToppCell	LPS-IL1RA-Unknown\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZNF317 SPAG5 SLC26A8 FCER2 NRXN2	3.96e-05	118	143	5	6cb4063b83f867b782080ce5b1199b51bb277f2a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CASR MET PRKCQ SSH2 DNAH5 BICC1	4.01e-05	195	143	6	938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CASR MET PRKCQ SSH2 DNAH5 BICC1	4.01e-05	195	143	6	d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-Teffector/EM_CD4\|Liver / Manually curated celltypes from each tissue	ARHGAP15 EEF1G EEF2 CD5 AHNAK RPL5	4.12e-05	196	143	6	88cafaac9530c648b3ef5ad04b79c7bed8978bb6
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLT1 SPTBN1 EBF1 STOX2 GIMAP8 RIN2	4.12e-05	196	143	6	8f2031b1a9232c389517fbf3c29f47f9468b0077
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLT1 SPTBN1 EBF1 STOX2 GIMAP8 RIN2	4.12e-05	196	143	6	48b4a9cea97a55190217deaf51bf867608c5a9a7
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLT1 SPTBN1 EBF1 STOX2 GIMAP8 RIN2	4.12e-05	196	143	6	473980c827443464d08a0be28c53e3536369b12a
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Deep_Layer\|World / Primary Cells by Cluster	EBF3 EBF1 EBF2 EEF1G CNTNAP2 KIF5C	4.24e-05	197	143	6	41e823b14697827f657b13adb3afa581bd91a9cb
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-Teffector/EM_CD4\|lymph-node_spleen / Manually curated celltypes from each tissue	ARHGAP15 EEF1G CD5 AHNAK KIF5C RPL5	4.24e-05	197	143	6	b3808ad7b1562a51c6b99dd40c78433fac722e3a
ToppCell	Skin-Mesangial\|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.	FAM184B ADAM7 EBF1 TTBK1 EBF4 AMIGO2	4.48e-05	199	143	6	bcb78838a91cc7828680fb413fbacdb091c5fac0
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EBF3 EBF1 EBF2 AHNAK SEPTIN7 BICC1	4.48e-05	199	143	6	9846d6a31635fde759d55674631c11ab9270a603
ToppCell	Sigmoid-T_cell-Activated_CD4_T\|T_cell / Region, Cell class and subclass	VMP1 ARHGAP15 NDUFV2 CD5 AHNAK RPL5	4.61e-05	200	143	6	9c21e6b8d4f8e526950adacf9cc45a5e86d81c1f
ToppCell	LPS-IL1RA-Unknown-Endothelial-Pericyte_2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EBF1 SPAG5 SLC26A8 FCER2 EBF4	5.22e-05	125	143	5	2938a1d62afe1e0a3abba5eb92f07b886cc0accd
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KNTC1 FLT1 SPAG5 CD5 NOTCH1	5.22e-05	125	143	5	35042ed43045dddc341b76cc5f9fe31b5ba0abb8
ToppCell	facs-Lung-Endomucin-24m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN23 EPG5 MET ANAPC10 ARMC6	9.55e-05	142	143	5	0a87c0d74e281da5dc4f59e09a5e99c62b1ea801
ToppCell	Hippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Nxph3-Excitatory_Neuron.Slc17a7-Slc17a6.Nxph3-Nts_(Subiculum)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ZNF473 ZP2 RHAG FCER2	1.05e-04	76	143	4	355a6793e2828728da62357bd2250735b0fd76b1
ToppCell	Hippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Nxph3-Excitatory_Neuron.Slc17a7-Slc17a6.Nxph3-Nts_(Subiculum)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ZNF473 ZP2 RHAG FCER2	1.05e-04	76	143	4	2c304b41c04a567874126df25b15d8ee2ad2b6d9
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW08-Neuronal\|GW08 / Sample Type, Dataset, Time_group, and Cell type.	EEF1G CNTNAP2 KIF5C RPL5	1.28e-04	80	143	4	5c39136f5f855efbf61e1f5348ea97ea2130b241
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EBF1 ZNF804A DGKK KIF5C ANO3	1.31e-04	152	143	5	bd1f36b436d8ab7dd8420f595b97d851eab31a38
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EBF1 ZNF804A DGKK KIF5C ANO3	1.31e-04	152	143	5	ee329249a034a969a16b26a224aa04249d67382d
ToppCell	droplet-Liver-Hepatocytes-18m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRLF2 MAGI2 RAVER2 DOCK7 LRP1	1.58e-04	158	143	5	d3446fc98eff09c3626b47a2c90d07cd985378b5
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-2\|TCGA-Lung / Sample_Type by Project: Shred V9	ZNF492 ZBTB12 KIF5C TRIM36 ZNF98	1.58e-04	158	143	5	9dea15b28f64206bac0e785df6f36a2cc9010ac7
ToppCell	droplet-Liver-Hepatocytes-18m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRLF2 MAGI2 RAVER2 DOCK7 LRP1	1.58e-04	158	143	5	df614450e10629dc9115d7365397663e82f9e48f
ToppCell	3'-Adult-Distal_Rectal-Epithelial-goblet-BEST2+_Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LYPD6B ABHD3 ZBTB12 IQCN ITPR2	1.62e-04	159	143	5	6ec5489d55667e53bd9c021ada7de458bfef43a3
ToppCell	10x3'2.3-week_12-13-Hematopoietic-HSC/MPP_and_pro-CMP\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ZBTB16 EEF2 SV2B NOS2 RPL5	1.67e-04	160	143	5	be46daf3b42591768c83062a3bb4820efbf88bec
ToppCell	Thalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)\|Thalamus / BrainAtlas - Mouse McCarroll V32	HTR4 CFTR CD5 EBF4 AMIGO2	1.72e-04	161	143	5	0605134a342d74ae81f33700d6ddfcd6e03aeb7b
ToppCell	LPS-IL1RA-Epithelial_airway\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LYPD6B HP KIF5C DNAH5 ANO3	1.72e-04	161	143	5	472c354f5ee148b37a5dfb795e83348ecb1643f1
ToppCell	11.5-Distal-RBC\|Distal / Age, Tissue, Lineage and Cell class	SLC25A37 ADCY7 RHAG CAPRIN2 ZNF81	1.82e-04	163	143	5	e9d814952d824539ff1dea119e4fca14a8c335a8
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AVL9 BRWD3 TTBK1 PRKCQ KIF5C	1.82e-04	163	143	5	4af92b211d12c5b88b65bb746242cd702b545bd0
ToppCell	11.5-Distal-RBC-RBC\|Distal / Age, Tissue, Lineage and Cell class	SLC25A37 ADCY7 RHAG CAPRIN2 ZNF81	1.82e-04	163	143	5	31b60e065bac4ad380247964e7574f210106ebae
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_1\|E16.5-samps / Age Group, Lineage, Cell class and subclass	ZBTB16 ZNF7 CNTNAP2 LRP1 AMIGO2	1.82e-04	163	143	5	f1ec2625b52664308968b01d8e0275e1e0751480
ToppCell	10x5'-GI_large-bowel-Lymphocytic_T_CD4-Tfh\|GI_large-bowel / Manually curated celltypes from each tissue	PDS5B FLT1 ZNF175 SALL2 SSH2	1.82e-04	163	143	5	4104d3b9748b39cb0744c9be76db21bdda566a0d
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-CD4+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AVL9 BRWD3 TTBK1 PRKCQ KIF5C	1.82e-04	163	143	5	d24774e0aa612322c22fdb3b314aef275fa01d68
ToppCell	LPS_only-Epithelial_airway-Club_cells-Airway\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LYPD6B HP KIF5C DNAH5 ANO3	1.87e-04	164	143	5	b1243b10591e1e15a94952e39ffbf382eae6aae8
ToppCell	facs-Lung-EPCAM-3m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZBTB48 BCAR1 RAVER2 MLF1 AMIGO2	1.87e-04	164	143	5	1d0d88132baaa3154c3e6e4ef0aff795afab08a2
ToppCell	LPS_only-Epithelial_airway-Club_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LYPD6B HP KIF5C DNAH5 ANO3	1.87e-04	164	143	5	c5b2001280a43da855017361a3f6071a0e492848
ToppCell	facs-Lung-EPCAM-3m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZBTB48 BCAR1 RAVER2 MLF1 AMIGO2	1.87e-04	164	143	5	bd2e10b015d5e6a338675500ec5d81dc39583b3e
ToppCell	LPS_only-Epithelial_airway\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LYPD6B HP KIF5C DNAH5 ANO3	1.87e-04	164	143	5	56e6934e6c7503a300d7be06762d45a1d6f1ae0f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 LIN9 TTBK1 MED17 KNL1	1.93e-04	165	143	5	88681101d7cf60b99b8ace5d8c0944323b937306
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLT1 SPTBN1 RHAG GIMAP8 HDC	1.93e-04	165	143	5	6a621b300442c52adfc15b61d3a6d3a3cb00099f
ToppCell	LPS-IL1RA-Epithelial_airway-Club_cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LYPD6B CFTR HP KIF5C ANO3	1.93e-04	165	143	5	1a114eacaab598f755a173a3fed842ba91f689dd
ToppCell	368C-Myeloid-Dendritic-cDC_activated\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	CAMK1G STOX2 CD5 FCER2 LONRF2	1.93e-04	165	143	5	9d2bdc42c13c8c2a68889bec8612a1ce56f659fa
ToppCell	LPS-IL1RA-Epithelial_airway-Club_cells-Airway\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LYPD6B CFTR HP KIF5C ANO3	1.93e-04	165	143	5	9cfd3c1d2c6d714fde83b90465f1f9741b0e50ce
ToppCell	LPS-antiTNF-Epithelial_airway-Club_cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LYPD6B CFTR HP KIF5C ANO3	1.98e-04	166	143	5	1df4bdf7c773cbfa6c93d7a901f9cd3f3fe07a3d
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KNTC1 ARHGAP15 SMC2 CD5 PRKCQ	1.98e-04	166	143	5	a41a20cef053c67da2d435e3e132ce28f1661c03
ToppCell	LPS-antiTNF-Epithelial_airway-Club_cells-Airway\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LYPD6B CFTR HP KIF5C ANO3	1.98e-04	166	143	5	9628522e7af8f8edca733588a364ab2454ac5ca5
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMC2 SLC25A37 HP KIF5B KNL1	2.04e-04	167	143	5	1bd27ffe381d26731b6d4cc5f29b27f1bac4473b
ToppCell	Control-B_cells-Activated_B_cells\|Control / group, cell type (main and fine annotations)	ARHGAP15 EBF1 ZNF804A FCER2 CNTNAP2	2.10e-04	168	143	5	a7159a35fe37f8c241cf8d391debe271e0698105
ToppCell	droplet-Marrow-BM-1m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNST MET STOX2 AHNAK LRP1	2.10e-04	168	143	5	2e88d9cb7c80a4656fab290db8b45a5a0599d769
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGAP15 ZP2 CD5 PRKCQ RPL5	2.10e-04	168	143	5	68ee3b3b012b56584e313813feb16e632e3f72d2
ToppCell	PND07-Epithelial-Epithelial_Airway-Basal-Basal-Basal_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FAM184B LYPD6B HTR4 EBF3 SPAG5	2.10e-04	168	143	5	f150beee37e0252951a88adcd9e3f0a22e5cfdd9
ToppCell	E18.5-Immune-Immune_Myeloid-Granulocytic-Basophil\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARHGAP15 CRLF2 CD300LB SSH2 HDC	2.15e-04	169	143	5	b23d0aaa2da333b9c69a7aee862d5a5d2a1bf79b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FAM184B HTR4 ITPR2 EBF2 LONRF2	2.15e-04	169	143	5	2a21f2cef959526bfe3c8f081f4f7e9dd4e01a37
ToppCell	droplet-Lung-nan-3m-Lymphocytic-T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KNTC1 ZNF473 CD5 PRKCQ KIF5C	2.15e-04	169	143	5	df2c9c706bfc9db2bc5726602a49f5f5a94e9481
ToppCell	droplet-Lung-nan-3m-Lymphocytic-Proliferating_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KNTC1 ZNF473 CD5 PRKCQ KIF5C	2.15e-04	169	143	5	f6a6d2f614d60395ad9b867ff1cf59eba72b04ce
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAM184B HTR4 ITPR2 EBF2 LONRF2	2.15e-04	169	143	5	4b3a7b4a497178799b6b2f0b744f5fb752cee31a
Drug	vinylene	ZNF492 ZBTB16 ZNF175 SPTBN1 EBF1 ZNF71 ZNF197 ZNF264 ZNF81 ZNF98 PRDM15	4.43e-07	245	143	11	CID000006326
Disease	retinopathy of prematurity (biomarker_via_orthology)	FLT1 NOS2 NOTCH1	2.09e-05	12	137	3	DOID:13025 (biomarker_via_orthology)
Disease	Sarcomatoid Renal Cell Carcinoma	TET2 FLT1 ZNF804A MET EEF2 AHNAK	3.06e-05	128	137	6	C1266043
Disease	Chromophobe Renal Cell Carcinoma	TET2 FLT1 ZNF804A MET EEF2 AHNAK	3.06e-05	128	137	6	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	TET2 FLT1 ZNF804A MET EEF2 AHNAK	3.06e-05	128	137	6	C1266044
Disease	Papillary Renal Cell Carcinoma	TET2 FLT1 ZNF804A MET EEF2 AHNAK	3.06e-05	128	137	6	C1306837
Disease	Renal Cell Carcinoma	TET2 FLT1 ZNF804A MET EEF2 AHNAK	3.06e-05	128	137	6	C0007134
Disease	Hypoparathyroidism familial isolated	GCM2 CASR	6.40e-05	3	137	2	C1832648
Disease	neutrophil count, eosinophil count	TET2 VMP1 UBR2 ZBTB16 HTR4 MAML1 LIN9	6.44e-05	213	137	7	EFO_0004833, EFO_0004842
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	TET2 FLT1 ZNF804A MET EEF2 AHNAK	6.89e-05	148	137	6	C0279702
Disease	neutrophil count, basophil count	TET2 VMP1 UBR2 ZBTB16 HTR4 MAML1 LIN9	8.82e-05	224	137	7	EFO_0004833, EFO_0005090
Disease	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	ZBTB16 SALL2 RPL5 NOTCH1	1.09e-04	53	137	4	C1961099
Disease	Familial Isolated Hyperparathyroidism	GCM2 CASR	1.28e-04	4	137	2	C4551961
Disease	Gilles de la Tourette syndrome (implicated_via_orthology)	MET HDC	1.28e-04	4	137	2	DOID:11119 (implicated_via_orthology)
Disease	waist-hip ratio	TET2 KNTC1 EFL1 ZNF280D ZNF268 SLC38A9 CFTR EBF1 IQCN EBF2 ANAPC10 AHNAK CAPRIN2 LONRF2 ANO3 KNL1	1.88e-04	1226	137	16	EFO_0004343
Disease	colon adenocarcinoma (is_marker_for)	TET2 EEF2 NOS2	2.09e-04	25	137	3	DOID:234 (is_marker_for)
Disease	preeclampsia, fetal genotype effect measurement	FLT1 ITPR2	2.12e-04	5	137	2	EFO_0000668, EFO_0007959
Disease	hyperparathyroidism (is_implicated_in)	GCM2 CASR	2.12e-04	5	137	2	DOID:13543 (is_implicated_in)
Disease	Antihypertensive use measurement	VMP1 HTR4 ARHGAP15 EBF1 EBF2 TRIM36 BICC1	2.48e-04	265	137	7	EFO_0009927
Disease	Schizophrenia	HTR4 ZNF804A ADCY7 NDUFV2 MAGI2 MET SLC26A8 NRXN2 HP CNTNAP2 LRP1 SEPTIN7 SDHA	2.49e-04	883	137	13	C0036341
Disease	birth weight, parental genotype effect measurement	TET2 EBF1 BCAR1 SLC25A37 ITPR2 CAPRIN2	2.85e-04	192	137	6	EFO_0004344, EFO_0005939
Disease	testosterone measurement	TET2 FAM184B EFL1 ZNF280D MYO5A EBF1 IQCN SLC25A37 EBF2 UBE4A TTBK1 RIN2 DGKK CNTNAP2 PRKCQ KNL1	2.92e-04	1275	137	16	EFO_0004908
Disease	Sinusitis	CFTR MET	4.43e-04	7	137	2	C0037199
Disease	Hereditary pancreatitis	CFTR CASR	4.43e-04	7	137	2	C0238339
Disease	hemolytic anemia (is_implicated_in)	RHAG HP	5.88e-04	8	137	2	DOID:583 (is_implicated_in)
Disease	monocyte percentage of leukocytes	VMP1 UBR2 ZBTB16 HTR4 MAML1 EBF1 LIN9 ANAPC10 FCER2 AHNAK SSH2	6.30e-04	731	137	11	EFO_0007989
Disease	low affinity immunoglobulin epsilon Fc receptor measurement	EBF1 FCER2	7.54e-04	9	137	2	EFO_0008210
Disease	Retinal Pigment Epithelial Detachment	HP PRKCQ	7.54e-04	9	137	2	C0339546
Disease	spinal muscular atrophy (implicated_via_orthology)	KIF5B KIF5C	7.54e-04	9	137	2	DOID:12377 (implicated_via_orthology)
Disease	aspartate aminotransferase to alanine aminotransferase ratio	USP16 ZNF7 ZNF16 GIMAP8 AHNAK ARMC6	9.02e-04	239	137	6	EFO_0010934
Disease	Major Depressive Disorder	ZBTB16 ADCY7 NDUFV2 HP CNTNAP2 LRP1	9.82e-04	243	137	6	C1269683
Disease	Retinal Detachment	HP PRKCQ	1.15e-03	11	137	2	C0035305
Disease	forced expiratory volume, response to bronchodilator	TET2 EBF1 RLF EEF1G FCER2 NRXN2 AHNAK DNAH5	1.16e-03	445	137	8	EFO_0004314, GO_0097366
Disease	granulocyte count	TET2 VMP1 ZBTB16 HTR4 MAML1 LIN9	1.23e-03	254	137	6	EFO_0007987
Disease	Unipolar Depression	ZBTB16 ADCY7 NDUFV2 HP CNTNAP2 LRP1	1.36e-03	259	137	6	C0041696
Disease	motor neuron disease (implicated_via_orthology)	KIF5B KIF5C	1.37e-03	12	137	2	DOID:231 (implicated_via_orthology)
Disease	myeloid white cell count	TET2 VMP1 UBR2 ZBTB16 HTR4 ARHGAP15 SLC38A9 SPTBN1 EBF1 LIN9 MET SSH2	1.45e-03	937	137	12	EFO_0007988
Disease	Neoplasm Invasiveness	ZBTB16 BCAR1 MET EEF2 AHNAK	1.72e-03	184	137	5	C0027626
Disease	Kawasaki disease (is_marker_for)	FLT1 HP	1.88e-03	14	137	2	DOID:13378 (is_marker_for)
Disease	intelligence, self reported educational attainment	TET2 EFL1 ARHGAP15 TRIM36	2.20e-03	117	137	4	EFO_0004337, EFO_0004784
Disease	pursuit maintenance gain measurement	EPG5 MAGI2 BICC1 EBF4	2.64e-03	123	137	4	EFO_0008433
Disease	birth weight	TET2 FLT1 TENT4B EBF1 SLC25A37 ADCY7 ITPR2	2.68e-03	399	137	7	EFO_0004344
Disease	hematocrit	VMP1 HTR4 ARHGAP15 EBF1 DNAAF9 SLC25A37 ITPR2 MET DGKK SSH2 SPRTN BICC1	2.71e-03	1011	137	12	EFO_0004348
Disease	cervical artery dissection	ZNF804A LRP1	2.78e-03	17	137	2	EFO_1000059
Disease	oral squamous cell carcinoma (is_marker_for)	TET2 MET HP	3.17e-03	63	137	3	DOID:0050866 (is_marker_for)
Disease	cholangiocarcinoma (is_marker_for)	MET NOS2 NOTCH1	3.32e-03	64	137	3	DOID:4947 (is_marker_for)
Disease	low density lipoprotein cholesterol measurement, physical activity	SLC25A35 CNTNAP2 PRDM15	3.62e-03	66	137	3	EFO_0003940, EFO_0004611
Disease	Malaria	HP NOS2	3.85e-03	20	137	2	C0024530
Disease	atherosclerosis (biomarker_via_orthology)	CASR HP	3.85e-03	20	137	2	DOID:1936 (biomarker_via_orthology)
Disease	level of Phosphatidylcholine (16:0_20:4) in blood serum	CD5 AHNAK	4.24e-03	21	137	2	OBA_2045076
Disease	cardiomyopathy (implicated_via_orthology)	CASR LRP1 SDHA	4.44e-03	71	137	3	DOID:0050700 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
VSGLDNMATHLSQHK	ZNF280D	701	Q6N043
HGDNVKLLNSMIQAH	EPG5	1116	Q9HCE0
GMHKNEAISQQLHVL	EPG5	1606	Q9HCE0
NLMTHSVNQGQNIHR	CFTR	771	P13569
QKMEDVHQTLVAHGQ	BCAR1	546	P56945
TNIIANRMAHQLGHN	ADAM7	326	Q9H2U9
EPQKNAMAHRNSTHQ	CASR	981	P41180
HAHNHAKMIVQENKG	ARMC6	261	Q6NXE6
SSLNEGENTHMIHQK	EFL1	781	Q7Z2Z2
TGMNQNMSFHRNHTA	CD5	421	P06127
AVSDNMFVHNNSKHG	EBF2	226	Q9HAK2
QSSVNKHRHMFVKQV	ABHD3	276	Q8WU67
HSSQIEGVRQMHNNA	BRWD3	701	Q6RI45
MQQHSGQHLITAVAD	AARSD1	106	Q9BTE6
NPNKRNVHNETSMHL	ANKIB1	71	Q9P2G1
QSGEVTQLLNTMGHH	AHNAK	66	Q09666
QKNMLHQSNAHSSIL	AMIGO2	431	Q86SJ2
IHFQIKNGSVMSHLG	ATG10	46	Q9H0Y0
RTLQIQKAHGDHMAS	DDX20	481	Q9UHI6
QKAHGDHMASSRNNS	DDX20	486	Q9UHI6
NLTGAFHKHQMQDAS	ADCY7	191	P51828
AAKQRELHSHVTNAM	DHCR7	256	Q9UBM7
NIKHIMQRTGAQIHF	BICC1	306	Q9H694
MVHHSGSIQSFKQQK	ANO3	1	Q9BYT9
HLNKAHQSSVMGNTS	RAVER2	391	Q9HCJ3
NQHSLNILGQKVSMH	RBM10	191	P98175
LFSVINNGHNQKVHM	PDS5B	161	Q9NTI5
MHSQTHLATGAVKVQ	IQCN	716	Q9H0B3
TNSELHRAMNLHVGN	PTPN23	511	Q9H3S7
NQHQRLLKNMGAHSV	ITPR2	1201	Q14571
GKSNRHVAVTNMNEH	KIF5B	186	P33176
FQKQNVTIMDHHSAA	NOS2	426	P35228
HGSLMTNKQHQGKSN	TENT4B	536	Q8NDF8
AHVGHSVAAQISNNM	RAB3GAP2	841	Q9H2M9
VKNLQAHVRHGTEMA	HDC	371	P19113
SGEAIQIHHQTRQNM	DEPDC5	626	O75140
TAASSFHMQQQAHLK	MAML1	861	Q92585
SKIHQHVSVLMGSVN	DGKK	1096	Q5KSL6
GMNVHHRCQTKVANL	PRKCQ	266	Q04759
HTNVVFKRDAHGQQM	NOTCH1	1601	P46531
NASNHNSHVVDMLRK	HCFC2	471	Q9Y5Z7
IHVAHIQSGLSQMGN	LIN9	516	Q5TKA1
VIDLMHHAARNGQVN	MAGI2	841	Q86UL8
QAKMVSHHNLTTGAT	HP	176	P00738
AQMDQVKSQGADLHH	MTMR8	596	Q96EF0
MHLNGSNVQVLHRTG	LRP1	3086	Q07954
QNHAMKAQLEASHQR	FAM184B	651	Q9ULE4
QVSKNLESHHGDQMA	FCER2	66	P06734
LESHHGDQMAQKSQS	FCER2	71	P06734
NLRQHAGIGHAMVNK	NRXN2	381	Q9P2S2
GNKAHNDMHIVQATE	KNL1	1616	Q8NG31
HMNTGQLAGFSHQIR	KNTC1	2111	P50748
SSIQSRLKAQGHSHM	LONRF2	326	Q1L5Z9
RLKAQGHSHMNAQAL	LONRF2	331	Q1L5Z9
QHQVHAVQQLAKVMG	MED17	531	Q9NVC6
VQMLSRNLEGHHQIA	NLRX1	351	Q86UT6
QNVAHLHKMAGAEQE	CRLF2	291	Q9HC73
QAFNAAAVVHHMRKL	CAMK1G	306	Q96NX5
NIGRKVDSHQHQKMQ	OTOP1	291	Q7RTM1
VLANHQNGRDTHMRQ	ANAPC10	141	Q9UM13
LQNMAGKHSERSNHA	DOCK7	1691	Q96N67
DNMFVHNNSKHGRRA	EBF4	231	Q9BQW3
VKHHIANANLMRNGA	DHPS	286	P49366
HTNLGTIRKVMAGNH	AVL9	271	Q8NBF6
SMVHQNGNKHCVFRE	GIMAP8	421	Q8ND71
LRSKMTFHIHAVNNQ	DNAAF9	421	Q5TEA3
EHAHQIQMLQRAGAS	HTR4	221	Q13639
LAVSDNMFVHNNSKH	EBF1	226	Q9UH73
NMKSAKPQVNHSQHG	CAPRIN2	81	Q6IMN6
MESKTGHRNSEHQQG	MARF1	656	Q9Y4F3
NMANGQPHSVNITRH	CNTNAP2	1106	Q9UHC6
PTLGIMHHNKQATEN	EEF1G	116	P26641
KANIRNMSVIAHVDH	EEF2	16	P13639
LAVSDNMFVHNNSKH	EBF3	226	Q9H4W6
HQGMFQALTEIGQKH	SLC25A35	146	Q3KQZ1
TNAVTLQQHVRMHLG	SALL2	701	Q9Y467
NHVIQRVSDHASAMN	SLC38A9	51	Q8NBW4
RNDTVGDHPAQMQHK	CNST	626	Q6PJW8
HFNHQNMDALLKVTR	DNAH5	961	Q8TE73
NKHFNMSIIISNGHG	MET	631	P08581
KLGGNHANHRVTTMS	TRIM36	236	Q9NQ86
HLKESHEMGQALQQA	SPAG5	486	Q96R06
NFTMENQIHQHGKLV	SV2B	441	Q7L1I2
QKSMQNHAAVFRVGS	SDHA	516	P31040
QMESHREAHQKQLSR	KIF5C	706	O60282
SGNMNINITTFRHHV	SLC26A8	46	Q96RN1
GSAMLHNRQNDVQIH	PRDM15	1416	P57071
MRNTNNHNGHILKKS	GCM2	66	O75603
ENMKRTLNDVFHHQG	SLC25A37	126	Q9NYZ2
TGAVQMRIKNANSHH	ARHGAP15	21	Q53QZ3
MRIKNANSHHDRLSQ	ARHGAP15	26	Q53QZ3
ENQMHKGVILGTANH	SHOX	176	O15266
NAEVHRKHIMGQNVA	RPL5	191	P46777
RVTLMAQHGSDQHQV	TEN1	41	Q86WV5
HQVLSMNRNAVGKHF	TEFM	271	Q96QE5
TVVGNAKHNVHVMNI	WDR13	276	Q9H1Z4
AVVNQIARQLMHSGH	SPTBN1	906	Q01082
NSNMAVFIGSHKRNH	CD300LB	136	A8K4G0
NFSRSSNLITHQKMH	ZNF572	336	Q7Z3I7
SHAFTQKANLNMHLR	ZBTB48	471	P10074
QKANLNMHLRTHTGE	ZBTB48	476	P10074
QTSMPETVNHNKHGN	RIN2	331	Q8WYP3
FSQNKNLVVHQRMHT	ZNF197	911	O14709
ASVNAHKNREMGRHD	TTBK1	206	Q5TCY1
KQFNHSSNLNRHMNV	ZBTB12	366	Q9Y330
SSNLNRHMNVHRGVK	ZBTB12	371	Q9Y330
AQSALQQHMEVHAGV	ZBTB16	501	Q05516
NTKSNLMVHQRTHTG	ZNF268	426	Q14587
VNIKSNHISQEGVMH	USP16	491	Q9Y5T5
GNLSIHMQSDKHLAN	ZFHX2	521	Q9C0A1
HLSMHNVENSNGDIK	RLF	821	Q13129
RNKHAGDLQQHLQAM	SSH2	66	Q76I76
RTHMQDLKDVTNNVH	SEPTIN7	291	Q16181
HKGDNFIMHSNTNVL	STOX2	416	Q9P2F5
HNLGNTRMRSVGHEN	MLF1	211	P58340
SNLMALKNHSRLHAQ	ZNF646	276	O15015
VEHRGKLNMVHIQNA	RHAG	261	Q02094
LSHTQNIGQMLRTHF	SMC2	1121	O95347
KHMHRINSLTGANIT	SPRTN	136	Q9H040
NSNLASHQRMHTGEK	ZNF677	331	Q86XU0
MTHKNNLTGQRVRHS	ZNF841	41	Q6ZN19
SSSLTQHQRMHTGKN	ZNF264	551	O43296
QHQRMHTGKNPISVT	ZNF264	556	O43296
FNNSSILNRHKMIHT	ZNF492	486	Q9P255
NSSLMVHQRTHTGEK	ZNF852	451	Q6ZMS4
KALNHGSHMTVRQVS	ZNF415	271	Q09FC8
FNMKTQLIVHQGVHT	ZNF26	351	P17031
AFNNSSILNRHKMIH	ZNF98	526	A6NK75
FSQNSVLKNRHRSHM	ZNF16	246	P17020
NHLRMHTGQKSHECQ	ZNF57	521	Q68EA5
HQVESMHGAGNAKKN	TARBP1	1321	Q13395
GFHRLHDQMVKINQN	UBE4A	521	Q14139
RVSQILQDHGHNVTM	UGT3A2	41	Q3SY77
SSRNNKEHHTQEMGV	TGM7	16	Q96PF1
LKGTQHIMQAGQTLH	FLT1	36	P17948
QVMHSSIVAHQNFGL	UBR2	301	Q8IWV8
AHRDLHNMQNGSTLV	TET2	1381	Q6N021
GRAFSQNMHLTEHQR	ZNF71	276	Q9NQZ8
HGGHQMTIRVMNNSA	ZP2	111	Q05996
TFRNQSILKTHMNSH	ZNF317	426	Q96PQ6
NQKSILSMHQRIHTG	ZNF175	541	Q9Y473
GFTQKSVLSMHRNIH	ZNF81	646	P51508
TLAQHQRMHTGEKAQ	ZNF7	376	P17097
FSDNNRLVQHQKMHT	ZNF473	496	Q8WTR7
NGQSNATMIHSGKHN	ZNF804A	701	Q7Z570
RRVAMNKEHHNGNFT	VMP1	11	Q96GC9
NQSSALTRHKMIHTG	ZNF257	326	Q9Y2Q1
AIRQNSHFIQHGGKM	ZNF554	281	Q86TJ5
NHGMALTIHNKINTA	ZNF554	306	Q86TJ5
TNHTNAVFAVMHAQR	LYPD6B	146	Q8NI32
GFMKHNTSRQNEHCL	MYO5A	1576	Q9Y4I1
HVRNLHKTVMQNGAG	NDUFV2	21	P19404