Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone H3K36 trimethyltransferase activity

SETD2 SETD5

1.01e-045642GO:0140955
GeneOntologyMolecularFunctionphosphatidylinositol 3-kinase inhibitor activity

WASH6P WASH3P

2.80e-048642GO:0141039
GeneOntologyMolecularFunctiondinucleotide phosphatase activity

CILP ENPP2

3.59e-049642GO:0004551
GeneOntologyMolecularFunctionalpha-tubulin binding

WASH6P WASH3P SETD2

6.20e-0452643GO:0043014
GeneOntologyMolecularFunctionhistone H3K36 methyltransferase activity

SETD2 SETD5

7.71e-0413642GO:0046975
GeneOntologyMolecularFunctioncalcium channel activity

TRPV6 PKD1L3 TRPV5 RYR2

7.83e-04129644GO:0005262
DomainTRPV5/TRPV6

TRPV6 TRPV5

1.08e-052622IPR008344
PathwayREACTOME_STIMULI_SENSING_CHANNELS

SGK1 ANO1 TRPV6 TRPV5 RYR2

1.35e-0599445MM14910
PathwayREACTOME_STIMULI_SENSING_CHANNELS

SGK1 ANO1 TRPV6 TRPV5 RYR2

1.88e-05106445M27200
PathwayREACTOME_ION_CHANNEL_TRANSPORT

SGK1 ANO1 TRPV6 TRPV5 RYR2

2.10e-04176445MM15718
PathwayREACTOME_ION_CHANNEL_TRANSPORT

SGK1 ANO1 TRPV6 TRPV5 RYR2

2.51e-04183445M997
Pubmed

Characterization of the murine orthologue of a novel human subtelomeric multigene family.

WASH6P WASH3P WASH4P

6.21e-08565311701968
Pubmed

Human subtelomeric WASH genes encode a new subclass of the WASP family.

WASH6P WASH3P WASH4P

1.24e-07665318159949
Pubmed

CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL.

WASH6P WASH3P CCDC22

1.02e-061165326965651
Pubmed

Alteration of calcium homeostasis in primary preeclamptic syncytiotrophoblasts: effect on calcium exchange in placenta.

TRPV6 TRPV5

3.44e-06265220178461
Pubmed

The TRPV5/6 calcium channels contain multiple calmodulin binding sites with differential binding properties.

TRPV6 TRPV5

3.44e-06265222354706
Pubmed

Diverse calcium channel types are present in the human placental syncytiotrophoblast basal membrane.

TRPV6 TRPV5

3.44e-06265216564089
Pubmed

Endogenous expression of TRPV5 and TRPV6 calcium channels in human leukemia K562 cells.

TRPV6 TRPV5

3.44e-06265219295174
Pubmed

Human TRPV5 and TRPV6: key players in cadmium and zinc toxicity.

TRPV6 TRPV5

3.44e-06265223968883
Pubmed

Expression of calcium channels along the differentiation of cultured trophoblast cells from human term placenta.

TRPV6 TRPV5

3.44e-06265212390878
Pubmed

Evaluation of serum ATX and LPA as potential diagnostic biomarkers in patients with pancreatic cancer.

ENPP2 LPA

3.44e-06265233568105
Pubmed

Homo- and heterotetrameric architecture of the epithelial Ca2+ channels TRPV5 and TRPV6.

TRPV6 TRPV5

3.44e-06265212574114
Pubmed

Structural conservation of the genes encoding CaT1, CaT2, and related cation channels.

TRPV6 TRPV5

3.44e-06265211549322
Pubmed

[TRPV5 and TRPV6 calcium channels in human T cells].

TRPV6 TRPV5

3.44e-06265219140341
Pubmed

TRPV5 and TRPV6 are expressed in placenta and bone tissues during pregnancy in mice.

TRPV6 TRPV5

3.44e-06265230916584
Pubmed

Setd5, but not Setd2, is indispensable for retinal cell survival and proliferation.

SETD2 SETD5

3.44e-06265236349512
Pubmed

Interaction of the epithelial Ca2+ channels TRPV5 and TRPV6 with the intestine- and kidney-enriched PDZ protein NHERF4.

TRPV6 TRPV5

3.44e-06265216565876
Pubmed

Age-dependent alterations in Ca2+ homeostasis: role of TRPV5 and TRPV6.

TRPV6 TRPV5

3.44e-06265216705151
Pubmed

TOX2 coordinates with TET2 to positively regulate central memory differentiation in human CAR T cells.

TET2 TOX2

3.44e-06265237467321
Pubmed

Expression of transient receptor potential vanilloid channels TRPV5 and TRPV6 in retinal pigment epithelium.

TRPV6 TRPV5

3.44e-06265220405023
Pubmed

A single amino acid mutation results in a rapid inactivation of epithelial calcium channels.

TRPV6 TRPV5

3.44e-06265211846401
Pubmed

First evidence of TRPV5 and TRPV6 channels in human parathyroid glands: possible involvement in neoplastic transformation.

TRPV6 TRPV5

3.44e-06265225164318
Pubmed

Expression and prognostic roles of TRPV5 and TRPV6 in non-small cell lung cancer after curative resection.

TRPV6 TRPV5

3.44e-06265224761864
Pubmed

Regulation of the mouse epithelial Ca2(+) channel TRPV6 by the Ca(2+)-sensor calmodulin.

TRPV6 TRPV5

3.44e-06265215123711
Pubmed

Fast and slow inactivation kinetics of the Ca2+ channels ECaC1 and ECaC2 (TRPV5 and TRPV6). Role of the intracellular loop located between transmembrane segments 2 and 3.

TRPV6 TRPV5

3.44e-06265212077127
Pubmed

Single-channel activities of the human epithelial Ca2+ transport proteins CaT1 and CaT2.

TRPV6 TRPV5

3.44e-06265211719848
Pubmed

Concerted action of associated proteins in the regulation of TRPV5 and TRPV6.

TRPV6 TRPV5

3.44e-06265217233615
Pubmed

[The functional characteristics oF TRPV5 and TRPV6 channels in normal and transformed human blood lymphocytes].

TRPV6 TRPV5

3.44e-06265224592736
Pubmed

Interaction network of human early embryonic transcription factors.

TET2 ZNF703 ZNF609 HIVEP2 ZMYM2 RERE AHDC1

4.23e-0635165738297188
Pubmed

Autotaxin Derived From Lipoprotein(a) and Valve Interstitial Cells Promotes Inflammation and Mineralization of the Aortic Valve.

ENPP2 LPA

1.03e-05365226224810
Pubmed

A molecular determinant of phosphoinositide affinity in mammalian TRPV channels.

TRPV6 TRPV5

1.03e-05365227291418
Pubmed

Changes in bile acid composition are correlated with reduced intestinal cholesterol uptake in intestine-specific WASH-deficient mice.

WASH6P WASH3P

1.03e-05365238086439
Pubmed

Calbindin-D28K dynamically controls TRPV5-mediated Ca2+ transport.

TRPV6 TRPV5

1.03e-05365216763551
Pubmed

Direct interaction with Rab11a targets the epithelial Ca2+ channels TRPV5 and TRPV6 to the plasma membrane.

TRPV6 TRPV5

1.03e-05365216354700
Pubmed

Prostatic acid phosphatase degrades lysophosphatidic acid in seminal plasma.

ENPP2 ACP3

1.03e-05365215280042
Pubmed

Lack of pendrin HCO3- transport elevates vestibular endolymphatic [Ca2+] by inhibition of acid-sensitive TRPV5 and TRPV6 channels.

TRPV6 TRPV5

1.03e-05365217200157
Pubmed

WASH Regulates Glucose Homeostasis by Facilitating Glut2 Receptor Recycling in Pancreatic β-Cells.

WASH6P WASH3P

1.03e-05365230425062
Pubmed

Dysregulation of the LPC-ATX-LPA axis in autoimmune hepatitis is associated with monocyte activation.

ENPP2 LPA

1.03e-05365237392838
Pubmed

Age-dependent changes in the expression of klotho protein, TRPV5 and TRPV6 in mouse inner ear.

TRPV6 TRPV5

1.03e-05365219922080
Pubmed

WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent manner.

WASH6P WASH3P

1.03e-05365225225459
Pubmed

Identification of BSPRY as a novel auxiliary protein inhibiting TRPV5 activity.

TRPV6 TRPV5

1.03e-05365216380433
Pubmed

Requirement of PDZ domains for the stimulation of the epithelial Ca2+ channel TRPV5 by the NHE regulating factor NHERF2 and the serum and glucocorticoid inducible kinase SGK1.

SGK1 TRPV5

1.03e-05365215665527
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

TET2 ZNF609 WDR33 ZMYM2 RERE AHDC1

1.12e-0526865633640491
Pubmed

WASH knockout T cells demonstrate defective receptor trafficking, proliferation, and effector function.

WASH6P WASH3P

2.06e-05465223275443
Pubmed

Inactivation of Rho GTPases by Burkholderia cenocepacia Induces a WASH-Mediated Actin Polymerization that Delays Phagosome Maturation.

WASH6P WASH3P

2.06e-05465232492429
Pubmed

The hepatic WASH complex is required for efficient plasma LDL and HDL cholesterol clearance.

WASH6P WASH3P

2.06e-05465231167970
Pubmed

Functional expression of the epithelial Ca(2+) channels (TRPV5 and TRPV6) requires association of the S100A10-annexin 2 complex.

TRPV6 TRPV5

2.06e-05465212660155
Pubmed

Loss of MAGEL2 in Prader-Willi syndrome leads to decreased secretory granule and neuropeptide production.

WASH6P WASH3P

2.06e-05465232879135
Pubmed

Trafficking defects in WASH-knockout fibroblasts originate from collapsed endosomal and lysosomal networks.

WASH6P WASH3P

2.06e-05465222718907
Pubmed

Regulation of the Ca(2+) channel TRPV6 by the kinases SGK1, PKB/Akt, and PIKfyve.

SGK1 TRPV6

2.06e-05465220041238
Pubmed

Dendritic cells utilize the evolutionarily conserved WASH and retromer complexes to promote MHCII recycling and helper T cell priming.

WASH6P WASH3P

2.06e-05465224886983
Pubmed

A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.

TRPV6 PKD1L3 TRPV5

3.27e-053365319834762
Pubmed

Calcium transport genes are differently regulated in maternal and fetal placenta in the knockout mice of calbindin-D(9k) and -D(28k).

TRPV6 TRPV5

3.43e-05565222407925
Pubmed

Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia.

WASH6P WASH3P

3.43e-05565224344185
Pubmed

Role and regulation of TRP channels in neutrophil granulocytes.

TRPV6 TRPV5

3.43e-05565212765698
Pubmed

Functional characterization of Wiskott-Aldrich syndrome protein and scar homolog (WASH), a bi-modular nucleation-promoting factor able to interact with biogenesis of lysosome-related organelle subunit 2 (BLOS2) and gamma-tubulin.

WASH6P WASH3P

3.43e-05565220308062
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

TRPV6 TRPV5 RYR2

5.02e-053865330786075
Pubmed

WASH complex regulates Arp2/3 complex for actin-based polar body extrusion in mouse oocytes.

WASH6P WASH3P

5.13e-05665224998208
Pubmed

WASH maintains NKp46+ ILC3 cells by promoting AHR expression.

WASH6P WASH3P

7.18e-05765228589939
Pubmed

Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development.

TRPV6 PKD1L3 TRPV5

7.81e-054465319322198
Pubmed

The Proteome of BLOC-1 Genetic Defects Identifies the Arp2/3 Actin Polymerization Complex to Function Downstream of the Schizophrenia Susceptibility Factor Dysbindin at the Synapse.

WASH6P WASH3P

9.56e-05865227927957
Pubmed

A FAM21-containing WASH complex regulates retromer-dependent sorting.

WASH6P WASH3P

9.56e-05865219922874
Pubmed

Cyclin M2 (CNNM2) knockout mice show mild hypomagnesaemia and developmental defects.

TRPV6 TRPV5

9.56e-05865233859252
Pubmed

Quantitative Trait Loci and a Novel Genetic Candidate for Fear Learning.

HIVEP2 SGK1

9.56e-05865227277803
Pubmed

Differentially regulated and evolved genes in the fully sequenced Xq/Yq pseudoautosomal region.

WASH6P WASH3P

9.56e-05865210655549
Pubmed

Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.

POSTN BNIP2 CDC42BPA ENPP2

9.96e-0512865430995482
Pubmed

Potential target genes of EMX2 include Odz/Ten-M and other gene families with implications for cortical patterning.

WASH6P WASH3P TENM1

1.22e-045165316919471
Pubmed

RNF2 is recruited by WASH to ubiquitinate AMBRA1 leading to downregulation of autophagy.

WASH6P WASH3P

1.23e-04965224980959
Pubmed

Regulation of WASH-dependent actin polymerization and protein trafficking by ubiquitination.

WASH6P WASH3P

1.53e-041065223452853
Pubmed

WASH inhibits autophagy through suppression of Beclin 1 ubiquitination.

WASH6P WASH3P

1.53e-041065223974797
Pubmed

Specific pupylation as IDEntity reporter (SPIDER) for the identification of protein-biomolecule interactions.

POSTN ACE2 TGM3

1.61e-045665337059927
Pubmed

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.

TET2 ZNF703 ZNF609 WDR33

1.93e-0415265438360978
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PLCD3 MST1R TPST2 NDST1 HIVEP2 CDC42BPA SETD5 TMC6 AHDC1

2.07e-04110565935748872
Pubmed

The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex.

WASH6P WASH3P

2.24e-041265219922875
Pubmed

Loss of strumpellin in the melanocytic lineage impairs the WASH Complex but does not affect coat colour.

WASH6P WASH3P

2.24e-041265227390154
Pubmed

Novel cell surface genes expressed in the stomach primordium during gastrointestinal morphogenesis of mouse embryos.

TRPV6 TRPV5

2.65e-041365222266179
Pubmed

Myotubularin-related proteins 3 and 4 interact with polo-like kinase 1 and centrosomal protein of 55 kDa to ensure proper abscission.

ZNF703 BNIP2 CCDC22 PIH1D1

2.76e-0416765425659891
Pubmed

A High-Density Map for Navigating the Human Polycomb Complexome.

ZNF703 TGM3 HIVEP2 ZMYM2 RERE AHDC1

3.27e-0449565627705803
Pubmed

Parkin mediates the ubiquitination of VPS35 and modulates retromer-dependent endosomal sorting.

WASH6P WASH3P

3.56e-041565229893854
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

ACE2 CDC42BPA ACP3 ALDH8A1 PKD1L3 CTSG SDCBP2 DOP1B

5.97e-04101665819056867
Pubmed

Histone H3 lysine 36 methyltransferase Hypb/Setd2 is required for embryonic vascular remodeling.

SETD2 LPA

6.39e-042065220133625
Pubmed

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.

POSTN CILP CTSG

8.10e-049765327559042
Pubmed

Mapping the expression of transient receptor potential channels across murine placental development.

TRPV6 TRPV5

9.24e-042465233884443
Pubmed

Loss of Hs3st3a1 or Hs3st3b1 enzymes alters heparan sulfate to reduce epithelial morphogenesis and adult salivary gland function.

POSTN NDST1

9.24e-042465234653670
Pubmed

International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels.

TRPV6 TRPV5

1.00e-032565216382100
Pubmed

Endocardial Brg1 disruption illustrates the developmental origins of semilunar valve disease.

POSTN ENPP2

1.00e-032565226100917
Pubmed

An introduction to TRP channels.

TRPV6 TRPV5

1.17e-032765216460286
Pubmed

NANOG-dependent function of TET1 and TET2 in establishment of pluripotency.

TET2 ZNF609

1.17e-032765223395962
Pubmed

SUMOylation of DDX39A Alters Binding and Export of Antiviral Transcripts to Control Innate Immunity.

WASH6P TPST2 FGD4 SH3GL3 TMC6 ALDH8A1 AHDC1

1.58e-0391565732393512
Pubmed

The antiobesity factor WDTC1 suppresses adipogenesis via the CRL4WDTC1 E3 ligase.

ACE2 STK17B RBMS2 PKD1L3 GNPAT

1.59e-0345365527113764
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

ZNF609 WDR33 RBMS2 PPCS AHDC1

1.66e-0345765532344865
Cytoband8p11.23

ZNF703 GOT1L1

1.29e-04126528p11.23
Cytoband2q14.3

CNTNAP5 WDR33

4.07e-04216522q14.3
CytobandEnsembl 112 genes in cytogenetic band chr6q23

SGK1 ALDH8A1 SLC18B1

6.60e-04119653chr6q23
CytobandEnsembl 112 genes in cytogenetic band chr15q22

ZNF609 BNIP2 CILP

8.91e-04132653chr15q22
CytobandEnsembl 112 genes in cytogenetic band chr7q34

TRPV6 TRPV5 MGAM2

2.34e-03185653chr7q34
GeneFamilyWiskott-Aldrich Syndrome protein family

WASH6P WASH3P WASH4P

7.37e-061644314
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_500_k-means-cluster#3

ZNF609 ACP3 MARCHF6 ANO1 TOX2

1.86e-05108645Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_500_K3
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel|Children_(3_yrs) / Lineage, Cell type, age group and donor

POSTN ENPP2 CTSG SDCBP2 TOX2

4.07e-06163655977a970b1296234c22178420294cea73506ee02f
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

POSTN HOXD3 ADAMTS4 CILP TOX2

6.59e-06180655455d1e3ccf2ab609954f3b870e8f514ddca735f4
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

POSTN ZNF703 FGD4 SGK1 TENM1

6.77e-06181655bd7e9437839bca543ca5945df43d6525e6a312a8
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

POSTN ZNF703 FGD4 SGK1 TENM1

7.73e-06186655948815663c212c4311329d503b5991cbbbff9808
ToppCellControl-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

POSTN FGD4 SGK1 RBMS2 TOX2

8.57e-061906557f3f419fffe02934b6f27b697f7a6401072491ed
ToppCellControl-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

FGD4 ENPP2 ANO1 TOX2 RYR2

9.24e-061936555896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCellEndothelial-A|World / lung cells shred on cell class, cell subclass, sample id

POSTN ADAMTS4 ENPP2 DCHS1 TOX2

1.05e-05198655dd096d4b9f428615f927f7df7cbf5cede0e0e605
ToppCellTracheal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_systemic_venous|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

POSTN HOXD3 ADAMTS4 ENPP2 DCHS1

1.07e-05199655d359f3e1595ba8d8a3dc9eb2e8f2b61f3247c7a1
ToppCell5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

POSTN ADAMTS4 ENPP2 RBMS2 DCHS1

1.07e-0519965507bda4ac8ffdce1a865ebc99e46c2a27925ff7a8
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6|Hippocampus / BrainAtlas - Mouse McCarroll V32

TGM3 TRPV6 SDCBP2 MYO5C

2.27e-051136546f270b7e59c18243e876311df721e948ce21e850
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Excitatory_Neuron.Slc17a6.Oprk1_(Claustrum_cortex)|Striatum / BrainAtlas - Mouse McCarroll V32

PLCD3 CNTNAP5 ELMO3 ZMYM2

3.70e-051286547e3f5cea91af005f08d8e9340fb8630bf1c887c3
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6|Striatum / BrainAtlas - Mouse McCarroll V32

PLCD3 CNTNAP5 ELMO3 ZMYM2

3.70e-05128654a876303c852db2af9418d1a1711d7c950805018a
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Excitatory_Neuron.Slc17a6.Oprk1_(Claustrum_cortex)-|Striatum / BrainAtlas - Mouse McCarroll V32

PLCD3 CNTNAP5 ELMO3 ZMYM2

3.70e-05128654388062f840fd04cb8087f27a9a78e7a192920e3e
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PLCD3 IGSF10 ACP3 SH3GL3

6.34e-05147654f5109e0f4e8b46a977a763c9c72a2df9840e3977
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PLCD3 IGSF10 ACP3 SH3GL3

6.34e-05147654ad0c575bc9c5f201f2a7810452e8b3f741e65d89
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage_3|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

PLCD3 SGK1 DCHS1 CTSG

7.79e-05155654c4dc0fa1d0e657753a56939eb4829fb60382c17f
ToppCellPND07-28-samps-Mesenchymal-Mesothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ELMO3 ANO1 TRPV6 RYR2

7.99e-05156654574f761962a7dd3308bd41fc529dd3ea1b8625f8
ToppCellPND07-28-samps-Mesenchymal-Mesothelial-Mesothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ELMO3 ANO1 TRPV6 RYR2

7.99e-05156654605d95a900e1443d3f6aae163ef2e893d3293203
ToppCell356C-Fibroblasts-Fibroblast-B_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

POSTN ENPP2 ANO1 SDCBP2

8.19e-05157654f6210be2362d833c6d869ff921188bfc85dda11d
ToppCell356C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

POSTN ENPP2 ANO1 SDCBP2

8.19e-0515765443a6b423fd70479822a564ff4225a1e4951ae5ed
ToppCellPosterior_cortex|World / BrainAtlas - Mouse McCarroll V32

TGM3 HIVEP2 TRPV6 RYR2

8.60e-0515965418e9fe2efbe0bca7c3990f3b12b6f549e2c1263a
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

POSTN ENPP2 CTSG SDCBP2

9.46e-05163654ba7d02db0f0e2f9916ec8db52c067c87b6917c23
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IGSF10 POSTN ACE2 ADAMTS4

1.02e-0416665449103b75c3e08656c5774f56fd00d7bd53eefcfb
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ONECUT2 NDST1 ADAMTS4 DCHS1

1.11e-041706541a568efcff9c39b3f709b55a05d24710450a2657
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ONECUT2 NDST1 ADAMTS4 DCHS1

1.11e-0417065466d41d794790e621d72ac37af995510537103c9c
ToppCellileum|World / shred on tissue and cell subclass

ACE2 STK17B SGK1 SDCBP2

1.11e-041706549f1211bd4287620e19a59f21e6ecdca3e42e0260
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MST1R POSTN ENPP2 ANO1

1.14e-0417165482de2885c8ce4fb7776da6a0207b3355c0910121
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MST1R POSTN ENPP2 ANO1

1.14e-0417165409e653973962fb884878089d281f0947f7a285f6
ToppCellAT1-AT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

PLCD3 MST1R ANO1 TRPV6

1.16e-041726540be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCelldroplet-Fat-Mat-18m-Lymphocytic-lymphocyte|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ONECUT2 HIVEP2 ALDH8A1 SDCBP2

1.16e-04172654226de1a5d4a360d3ae01b0235fea19521ec623a0
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STK17B SH3GL3 SDCBP2 TOX2

1.16e-041726541aecc98a3eadabae0f1f328091a9733d916017ec
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POSTN ACE2 ENPP2 RYR2

1.19e-041736543059325901b1e5e12a1a91183f14267288b2f600
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POSTN ACE2 ENPP2 RYR2

1.19e-0417365436c8338463ee4cc432f568728d55989360f9a68d
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC-cDC2-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TET2 FGD4 STK17B SGK1

1.27e-04176654a31d7532f8c055d4e62bbaa78d819f2495bfee00
ToppCellP15-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

POSTN ADAMTS4 FGD4 ANO1

1.27e-04176654792f414f5092aba14260b8e16378e793a822498e
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

POSTN TENM1 ANO1 TOX2

1.48e-0418365404d3cc76038b8192c915f1c08c3e26f2ad3b3779
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

POSTN ADAMTS4 ANO1 RYR2

1.51e-04184654689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

POSTN TENM1 ANO1 TOX2

1.51e-041846542ba98708dfd7f1b2a661578a334684094ff453ad
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HOXD3 FGD4 ACP3 MYO5C

1.51e-04184654d33de57876817050b294f2ecb0a4eb0634cfa7f0
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PLCD3 SGK1 ANO1 TOX2

1.51e-04184654ae0a77e3e520a246b17776bb19503519636b02ee
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

POSTN ADAMTS4 ANO1 RYR2

1.51e-04184654327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)-D231|Adult / Lineage, Cell type, age group and donor

POSTN SGK1 DCHS1 TOX2

1.54e-0418565407f9f38f0739d7c830641723a38385550ac1ac92
ToppCellEndothelial-A-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

POSTN ENPP2 DCHS1 TOX2

1.54e-04185654dee0b7ba2f338f0979d2306aedf52ac35a36b60c
ToppCellEndothelial-A-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

POSTN ENPP2 DCHS1 TOX2

1.57e-04186654796cbae2a417502aaf0891fc9c382bbfd88967fe
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-2|TCGA-Kidney / Sample_Type by Project: Shred V9

POSTN ADAMTS4 DCHS1 ANO1

1.57e-041866541e6526fc9e9381b7ace864588cc7bd80194338d6
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCD3 SGK1 ANO1 MYO5C

1.60e-041876549aa411ae9b5a923378a5daebb8bb2fc2613f2510
ToppCellEndothelial-A-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

POSTN ADAMTS4 ENPP2 DCHS1

1.67e-0418965404b565855f58ca0f343904d04be657b66e109076
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

POSTN SGK1 TENM1 ANO1

1.67e-0418965478cf414b98bcb19deb934409acddaad1cd51b67f
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

POSTN TENM1 ANO1 TOX2

1.71e-0419065426843ec1d19ac85a50990705353b802745d33e4d
ToppCelldroplet-Kidney-nan-3m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGSF10 POSTN ADAMTS4 CILP

1.71e-04190654f61e21d53f2f7804ac6e40ab6c7f69838aa94d6a
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_1|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

IGSF10 ONECUT2 CNTNAP5 RYR2

1.71e-041906546e92c78799f34b31d098854503c796edb0dc7f80
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

POSTN TENM1 ANO1 TOX2

1.71e-0419065439ab890104b4264c68a968f920f4ccd84f0bc681
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS4 ENPP2 TMC6 TRPV5

1.71e-041906546b101359f397020a21e2bfd15851cb48e71f4502
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

POSTN TENM1 ANO1 TOX2

1.71e-04190654e58e4b6fbeb4368f738adac67ec10879c0966f0f
ToppCellCOPD-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

POSTN ENPP2 ANO1 RYR2

1.78e-0419265462904f94dfce430456f05066522cbf9bd29f4d7e
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IGSF10 POSTN CILP ENPP2

1.81e-0419365464edc1d6fb0fe117767d494cf4a5723bf8be2804
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

POSTN TPST2 ENPP2 ANO1

1.81e-041936542f203f6f0c2135acb046c9351a633c3b5b254a46
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

POSTN TPST2 SGK1 TOX2

1.85e-0419465440842a7160f337bfc191ee15fbda3e3d38a04c57
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

POSTN CDC42BPA ENPP2 TOX2

1.88e-04195654023e3c97dd3696d74f002ff8da0c04d876c82aef
ToppCellEndothelial|World / shred by cell class for bronchial biopsy

POSTN NDST1 ENPP2 DCHS1

1.88e-04195654f0e46e859f7a9bdead3203889f7e20fa21f76ff0
ToppCellASK452|World / Donor, Lineage and Cell class of Lung cells from Dropseq

POSTN HIVEP2 ADAMTS4 RYR2

1.88e-041956547efd9d3a3f5e7dfe9698a4143ce4a0f9bf3a862c
ToppCellASK454-Endothelial-Endothelium|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

POSTN ADAMTS4 ENPP2 TOX2

1.92e-041966542b777a2026b56839112fd179f2db482c49f4594a
ToppCellnucseq-Endothelial-Endothelial_Vascular|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

POSTN CDC42BPA RBMS2 TOX2

1.92e-04196654686533fd3fba8e4df96b9dd1307e870e89db4332
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SGK1 TENM1 ANO1 TOX2

1.92e-041966547af6c5147ac859353504d19727dbe24f63a29dd4
ToppCellParenchymal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF703 ADAMTS4 ANO1 RYR2

1.96e-041976543f078be0b0f5e16edfb6d517beb20ac6178767f0
ToppCell3'-Adult-SmallIntestine|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

POSTN ONECUT2 ACE2 ENPP2

1.96e-041976541614bc5f41fd2c8385e58ed6b87ef1536421f29a
ToppCelldistal-Endothelial-Bronchial_Vessel_1-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

POSTN HOXD3 ADAMTS4 ENPP2

1.96e-041976540d1afd1ad7489c071db08b3dfff598423097d7e0
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Macroglial-oligodendrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS4 SGK1 ENPP2 SH3GL3

2.00e-04198654a183afe4c2034323f77abfa080f359d67da35e8f
ToppCelltumor_Lung-Endothelial_cells-Tumor_ECs|tumor_Lung / Location, Cell class and cell subclass

POSTN NDST1 ENPP2 DCHS1

2.00e-041986545228c4bf2513186140c2c4eaa67a268c732bdc84
ToppCellEndothelial_cells|World / lung cells shred on cell class, cell subclass, sample id

POSTN ADAMTS4 DCHS1 TOX2

2.00e-04198654b93effa428ec036542fa21647dfef9589c64640f
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

POSTN TPST2 SGK1 TOX2

2.04e-041996546cfe5a3d0ad530411ebc11decb4ab4c529e018d5
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-oligodendrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS4 SGK1 ENPP2 SH3GL3

2.04e-0419965467d8c7e5356f5d409d4f98e8338cf6c499fd7aee
ToppCellwk_15-18-Mesenchymal-Fibroblast-Alveolar_fibro|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

IGSF10 POSTN ENPP2 TOX2

2.04e-041996546bce8e65859a35cfea1c210f9c9765952d492ed2
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

POSTN TPST2 SGK1 TOX2

2.08e-04200654ec9a18576a3d08ddfceb70d114c4ab861fbb0d08
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

POSTN TPST2 SGK1 TOX2

2.08e-0420065424e43d3d16d07571f77e0cd5b2e4758c6ff802cb
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-WFDC2--L2-4|Neuronal / cells hierarchy compared to all cells using T-Statistic

POSTN FGD4 TENM1 TOX2

2.08e-04200654c65e6336725856c4b5f6aeba1cf86a23ec815d34
ToppCellcellseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

POSTN TPST2 SGK1 TOX2

2.08e-0420065413f6ac0dfc9206dd2e6cbd84357a5883952ee5c7
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte|LPS_only / Treatment groups by lineage, cell group, cell type

POSTN CILP ANO1 RYR2

2.08e-042006548c8ef2b19ab5b1bfc0fae6c38a330f464f28e86f
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FGD4 ANO1 MYO5C DOP1B

2.08e-042006540eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-WFDC2-|Neuronal / cells hierarchy compared to all cells using T-Statistic

POSTN FGD4 TENM1 TOX2

2.08e-04200654117a25b3b9cdbc2e198381350a8362bee25e82e7
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-WFDC2|Neuronal / cells hierarchy compared to all cells using T-Statistic

POSTN FGD4 TENM1 TOX2

2.08e-04200654d459e51507bf26865e6e7e04411379ec82a3edf8
DrugHelveticoside [630-64-8]; Up 200; 7.4uM; HL60; HT_HG-U133A

ZNF609 HIVEP2 WDR33 STK17B SGK1 ENPP2

4.70e-061596262192_UP
DrugRetinoic acid [302-79-4]; Down 200; 13.4uM; PC3; HT_HG-U133A

MST1R ZNF609 CDC42BPA RBMS2 TMC6 RYR2

1.55e-051966265767_DN
DrugMoricizine hydrochloride [31883-05-3]; Up 200; 8.6uM; MCF7; HT_HG-U133A

CDC42BPA WDR33 STK17B ACP3 TMC6 MARCHF6

1.55e-051966266000_UP
DrugCytisine (-) [485-35-8]; Down 200; 21uM; MCF7; HT_HG-U133A

ONECUT2 NDST1 ZNF609 HIVEP2 CDC42BPA STK17B

1.74e-052006262759_DN
Druglanthanum

LPA TRPV6 PKD1L3 TRPV5 RYR2

3.48e-05136625CID000023926
DrugAC1L2AC7

ACE2 TRPV6 PKD1L3 RYR2

3.77e-0569624CID000068733
DrugL-158,809

ACE2 RBMS2 RERE

4.24e-0525623CID000123856
Drug1kwq

ONECUT2 TRPV6 TRPV5

4.78e-0526623CID003092847
DrugN-cyclopentyl-N-cyclobutylformamide

ACE2 TRPV6 PKD1L3 RYR2

6.43e-0579624CID005287890
Drugatrial peptide

ACE2 ENPP2 LPA

8.19e-0531623CID005490906
DrugEmetine dihydrochloride [316-42-7]; Up 200; 7.2uM; HL60; HT_HG-U133A

HIVEP2 STK17B SGK1 ENPP2 MYO5C

8.23e-051636252145_UP
DrugMedroxyprogesterone Acetate

NDST1 CDC42BPA CILP SGK1 ENPP2 ACP3 TOX2

8.82e-05389627ctd:D017258
DrugCNS 1145

TRPV6 PKD1L3 RYR2

9.90e-0533623CID000190902
DrugIHC-64

TRPV6 PKD1L3 RYR2

9.90e-0533623CID000162753
Drugmanidipine

ACE2 TRPV6 PKD1L3 RYR2

1.32e-0495624CID000004008
Drugnitrendipine

ACE2 TRPV6 PKD1L3 RYR2

1.49e-0498624CID000004507
Drugisradipine

ACE2 TRPV6 PKD1L3 RYR2

1.61e-04100624CID000003784
DrugChloroquine diphosphate [50-63-5]; Down 200; 7.8uM; MCF7; HT_HG-U133A

NDST1 SETD2 ZNF609 CDC42BPA ZMYM2

1.69e-041906252869_DN
Drugcarbamazepine; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA

ONECUT2 ZNF609 WDR33 SGK1 TMC6

1.69e-04190625952_UP
DrugNSC759576

ACE2 HIVEP2 TRPV6 PKD1L3 RYR2

1.73e-04191625CID000003075
DrugNorethynodrel [68-23-5]; Up 200; 13.4uM; MCF7; HT_HG-U133A

SETD2 CCDC22 STK17B SGK1 RYR2

1.77e-041926251696_UP
DrugIsoflupredone acetate [338-98-7]; Down 200; 9.6uM; HL60; HT_HG-U133A

SETD2 ZNF609 ENPP2 ACP3 RERE

1.82e-041936251873_DN
DrugLY 294002; Down 200; 10uM; MCF7; HT_HG-U133A

ONECUT2 CDC42BPA SGK1 TMC6 AHDC1

1.86e-041946255599_DN
DrugDosulepin hydrochloride [897-15-4]; Down 200; 12uM; MCF7; HT_HG-U133A

SETD2 ZNF609 WDR33 TRPV6 RERE

1.86e-041946252864_DN
DrugMefloquine hydrochloride [51773-92-3]; Up 200; 9.6uM; HL60; HG-U133A

SETD2 SGK1 ENPP2 MARCHF6 ZMYM2

1.86e-041946251364_UP
DrugNomegestrol acetate [58652-20-3]; Down 200; 10.8uM; MCF7; HT_HG-U133A

NDST1 SETD2 ELMO3 CDC42BPA RYR2

1.95e-041966255461_DN
DrugFamprofazone [22881-35-2]; Down 200; 10.6uM; MCF7; HT_HG-U133A

ONECUT2 WDR33 SGK1 TMC6 MARCHF6

1.95e-041966256029_DN
DrugDinoprost trometamol [38362-01-5]; Down 200; 8.4uM; MCF7; HT_HG-U133A

ZNF609 ELMO3 TRPV6 AHDC1 RYR2

1.95e-041966255409_DN
DrugArcaine sulfate [14923-17-2]; Up 200; 14.8uM; MCF7; HT_HG-U133A

CDC42BPA CILP STK17B RERE DOP1B

1.95e-041966253349_UP
DrugChlorpropamide [94-20-2]; Up 200; 14.4uM; MCF7; HT_HG-U133A

ONECUT2 ZNF609 CDC42BPA CILP SH3GL3

1.95e-041966253210_UP
Drugnifedipine; Up 200; 10uM; MCF7; HG-U133A

NDST1 ELMO3 CDC42BPA SH3GL3 DCHS1

2.00e-04197625335_UP
Drugrofecoxib; Up 200; 10uM; MCF7; HG-U133A

ZNF609 CCDC22 CILP DCHS1 ZMYM2

2.00e-04197625205_UP
DrugBenfotiamine [22457-89-2]; Down 200; 8.6uM; MCF7; HT_HG-U133A

HIVEP2 WDR33 STK17B ACP3 RERE

2.00e-041976253931_DN
Drug(S)-(-)-Cycloserine [339-72-0]; Down 200; 39.2uM; MCF7; HT_HG-U133A

ONECUT2 ELMO3 CDC42BPA RBMS2 TMC6

2.00e-041976253870_DN
DrugAbbott-81988

ACE2 ENPP2

2.02e-048622CID000132387
DrugConvolamine hydrochloride [500-56-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A

ONECUT2 ZNF609 CCDC22 RERE AHDC1

2.05e-041986252771_DN
Drugtetraethylenepentamine pentahydrochloride; Down 200; 100uM; MCF7; HG-U133A

ONECUT2 ZNF609 ELMO3 TMC6 CTSG

2.05e-04198625406_DN
DrugDeltaline [6836-11-9]; Up 200; 7.8uM; HL60; HT_HG-U133A

ZNF609 HIVEP2 CDC42BPA HOXD3 TRPV5

2.05e-041986252171_UP
DrugTribenoside [10310-32-4]; Up 200; 8.4uM; PC3; HT_HG-U133A

ELMO3 CDC42BPA STK17B TMC6 RYR2

2.05e-041986256328_UP
DrugPirenperone [ 75444-65-4]; Up 200; 10.2uM; MCF7; HT_HG-U133A

MST1R ONECUT2 CDC42BPA CILP AHDC1

2.05e-041986255639_UP
DrugMoroxidine hydrochloride [3160-91-6]; Up 200; 19.2uM; MCF7; HT_HG-U133A

NDST1 SETD2 ZNF609 CCDC22 SGK1

2.05e-041986255304_UP
DrugDienestrol [84-17-3]; Down 200; 15uM; MCF7; HT_HG-U133A

NDST1 CCDC22 HIVEP2 CDC42BPA ZMYM2

2.05e-041986256208_DN
Druggadolinium

TRPV6 RERE PKD1L3 TRPV5 RYR2

2.10e-04199625CID000023982
DrugDacarbazine [4342-03-4]; Up 200; 22uM; MCF7; HT_HG-U133A

MST1R ONECUT2 STK17B ENPP2 SH3GL3

2.10e-041996256816_UP
DrugAceclofenac [89796-99-6]; Up 200; 11.2uM; MCF7; HT_HG-U133A

ONECUT2 STK17B RERE AHDC1 RYR2

2.10e-041996257029_UP
DrugEserine sulfate, physostigmine sulfate [64-47-1]; Up 200; 6.2uM; PC3; HT_HG-U133A

NDST1 ELMO3 WDR33 ACP3 RERE

2.10e-041996255749_UP
DrugKetorolac tromethamine [74103-07-4]; Up 200; 10.6uM; MCF7; HT_HG-U133A

ZNF609 CILP SGK1 RERE DOP1B

2.10e-041996256489_UP
Diseasecongestive heart failure (implicated_via_orthology)

POSTN ACE2 RYR2

8.06e-0541603DOID:6000 (implicated_via_orthology)
Diseasedegenerative disc disease (biomarker_via_orthology)

POSTN ADAMTS4

2.21e-0411602DOID:90 (biomarker_via_orthology)
Diseasenasopharynx carcinoma (is_implicated_in)

TET2 MST1R

4.20e-0415602DOID:9261 (is_implicated_in)
Diseasepain

ONECUT2 SH3GL3 RERE PKD1L3

6.88e-04196604EFO_0003843
Diseaseeosinophil percentage of leukocytes

SETD2 HIVEP2 ADAMTS4 STK17B ANO1 RERE TOX2

7.75e-04746607EFO_0007991
Diseaseazoospermia (implicated_via_orthology)

NDST1 CDC42BPA

1.38e-0327602DOID:14227 (implicated_via_orthology)
Diseaseneutrophil count

TET2 MST1R NDST1 SETD2 HIVEP2 CDC42BPA WDR33 RERE TOX2

1.81e-031382609EFO_0004833
Diseasemigraine disorder, glucose measurement

PLCD3 RERE

1.82e-0331602EFO_0004468, MONDO_0005277
Diseasetonsillectomy risk measurement

TET2 GPX6 RERE PKD1L3

1.95e-03260604EFO_0007924

Protein segments in the cluster

PeptideGeneStartEntry
LSLPARNQAGYFMLP

ALDH8A1

361

Q9H2A2
SQDPSLNYEYLPTMG

GOT1L1

61

Q8NHS2
LLPLQDTAYRYPGFM

AHDC1

1556

Q5TGY3
MDLGYPLELGYQNFL

CCDC22

76

O60826
FYPAPYNITPNRMLA

RBMS2

261

Q15434
YMLQLEAYDGGSPPR

DCHS1

221

Q96JQ0
NNPPYMPYLESRDKG

MGAM2

1396

Q2M2H8
LVYPPGFMGLAASLY

APOO

136

Q9BUR5
NLAPPGYFLLLSMLN

DOP1B

1796

Q9Y3R5
GRDMSEYFLPNPYLS

DDIAS

526

Q8IXT1
PLVLYMYGAPQDVRA

FGD4

671

Q96M96
ERGLPAMNNLYSPYK

ONECUT2

201

O95948
YLFLGMHPDLSSNYP

NDST1

621

P52848
LPNFLPYNVMLYSDA

MARCHF6

506

O60337
DYNLEPFAGLTPEYM

ANO1

716

Q5XXA6
QPNMYGLAAYTAPLS

HOXD3

306

P31249
FYGALTPMLNPLIYS

OR13H1

276

Q8NG92
EEGMYPDPGLLSYIN

NUTM1

401

Q86Y26
LQMALDVYNGLLPPY

ACP3

296

P15309
LNPLGPSAMFYLAAA

PPCS

166

Q9HAB8
YALNGEYTLMPSPTD

ADAMTS4

736

O75173
SYMPDLDSLYLHGNP

IGSF10

206

Q6WRI0
YNYDLPVPVIAAGMD

GNPAT

176

O15228
TDYGGLIFNSYMLPP

MT-CO2

111

P00403
AKLMNAYPSYISPIG

ACE2

246

Q9BYF1
SRTPEYYPNAGLIMN

LPA

631

P08519
VPPGLLALDNMLYFS

ELMO3

361

Q96BJ8
PESSQPNYRYLMDNL

BNIP2

176

Q12982
SRPYMAYLQIQSPAG

CTSG

31

P08311
AYUGLAAQYPELNAL

GPX6

71

P59796
AVAGALPPDYMESNY

RYR2

2671

Q92736
PNYPGIMYLQSDFDL

ENPP2

551

Q13822
NPEKPYAMALDYGGS

CNTNAP5

646

Q8WYK1
EYLQPNPAYRAKLGM

SH3GL3

56

Q99963
MGGPQQLYHLDAYIP

PIH1D1

246

Q9NWS0
LNMYILPNYESDPGE

SLC18B1

211

Q6NT16
LYGLPPFYSRNTAEM

SGK1

291

O00141
PDSPLLMTLYLGFQY

PKD1L3

551

Q7Z443
MGTPEYLAPEILNYD

STK17B

196

O94768
AYSPLNAMPRADGLY

SETD5

986

Q9C0A6
YNLALMTYPGNTGLL

TENM1

1626

Q9UKZ4
TDPLLAYHMPGLYNV

RERE

1281

Q9P2R6
LRYPLNGEGNPYSML

CDC42BPA

1381

Q5VT25
PVLYPNLAELENYMG

SDCBP2

41

Q9H190
NLSVDVYYDPMGNPL

TGM3

306

Q08188
YTMLAPLDPLGHNYG

CILP

1061

O75339
IAPMLAQLGYDPYAN

TPST2

316

O60704
ALPGHPLYTYGFMLQ

ZNF703

436

Q9H7S9
PLYTYGFMLQNEPLP

ZNF703

441

Q9H7S9
YPLMAGYQQLPSLNI

TRAPPC11

1081

Q7Z392
YPLGLRMNSANYSPQ

PLCD3

586

Q8N3E9
SYLPDLPGIANDLMY

WASH4P

261

A8MWX3
LLPAQYNLPYAAGLS

ZNF609

1376

O15014
IDGPANYNVDLPFMY

TRPV6

581

Q9H1D0
SYLPDLPGITNDLMY

WASH3P

246

C4AMC7
MTSPLPYDSLGYNAP

SETD2

2146

Q9BYW2
SLPQYQATMPDGKLY

ZMYM2

591

Q9UBW7
NGLLPAYSYQAMDLP

TOX2

111

Q96NM4
RVGGLPYNMPLAYLS

TMC6

331

Q7Z403
AGYYNDLVPPIGMLN

WDR33

86

Q9C0J8
PSMYNNLGLFINHYP

POSTN

186

Q15063
YHNPPLSMGQYLQAE

HIVEP2

2151

P31629
LGSYSPQSQPMDLYR

TET2

1646

Q6N021
DHYVQLPATYMNLGP

MST1R

1351

Q04912
YLPDLPSIANDLMYS

WASH6P

231

Q9NQA3
DPTSLGQFYDYPMAL

TRPV5

516

Q9NQA5
VAMNPYKQLPIYGDA

MYO5C

106

Q9NQX4