Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SCN11A CHRNA9 SLC1A2 SLC10A5 SLC1A6 HCN1 TRPC3 SCN2A TRPC4 TRPC5 SCN4A SLC5A3

1.67e-114653612GO:0046873
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

ANO9 SCN11A CHRNA9 SLC1A2 SLC10A5 SLC1A6 HCN1 TRPC3 SCN2A TRPC4 TRPC5 SCN4A SLC5A3

3.16e-107583613GO:0015318
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SCN11A CHRNA9 SLC1A2 SLC10A5 SLC1A6 HCN1 TRPC3 SCN2A TRPC4 TRPC5 SCN4A SLC5A3

5.20e-106273612GO:0022890
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

ANO9 SCN11A CHRNA9 SLC1A2 SLC10A5 SLC1A6 HCN1 TRPC3 SCN2A TRPC4 TRPC5 SCN4A SLC5A3

5.50e-107933613GO:0015075
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SCN11A SLC1A2 SLC10A5 SLC1A6 HCN1 SCN2A SCN4A SLC5A3

6.05e-10171368GO:0015081
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SCN11A CHRNA9 SLC1A2 SLC10A5 SLC1A6 HCN1 TRPC3 SCN2A TRPC4 TRPC5 SCN4A SLC5A3

9.97e-106643612GO:0008324
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-8 ERVK-6 ERVK-19 ERVK-25 ERVK-9

5.96e-0937365GO:0004190
GeneOntologyMolecularFunctiontransmembrane transporter activity

ANO9 SCN11A CHRNA9 SLC6A16 SLC1A2 SLC10A5 SLC1A6 HCN1 TRPC3 SCN2A TRPC4 TRPC5 SCN4A SLC5A3

6.53e-0911803614GO:0022857
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-8 ERVK-6 ERVK-19 ERVK-25 ERVK-9

6.86e-0938365GO:0070001
GeneOntologyMolecularFunctiontransporter activity

ANO9 SCN11A CHRNA9 SLC6A16 SLC1A2 SLC10A5 SLC1A6 HCN1 TRPC3 SCN2A TRPC4 TRPC5 SCN4A SLC5A3

2.01e-0812893614GO:0005215
GeneOntologyMolecularFunctionmonoatomic ion channel activity

ANO9 SCN11A CHRNA9 HCN1 TRPC3 SCN2A TRPC4 TRPC5 SCN4A

8.99e-08459369GO:0005216
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN11A HCN1 SCN2A SCN4A

1.29e-0726364GO:0005248
GeneOntologyMolecularFunctionmonoatomic cation channel activity

SCN11A CHRNA9 HCN1 TRPC3 SCN2A TRPC4 TRPC5 SCN4A

1.39e-07343368GO:0005261
GeneOntologyMolecularFunctionchannel activity

ANO9 SCN11A CHRNA9 HCN1 TRPC3 SCN2A TRPC4 TRPC5 SCN4A

2.80e-07525369GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

ANO9 SCN11A CHRNA9 HCN1 TRPC3 SCN2A TRPC4 TRPC5 SCN4A

2.85e-07526369GO:0022803
GeneOntologyMolecularFunctionstore-operated calcium channel activity

TRPC3 TRPC4 TRPC5

1.17e-0612363GO:0015279
GeneOntologyMolecularFunctioninositol 1,4,5 trisphosphate binding

TRPC3 TRPC4 TRPC5

1.93e-0614363GO:0070679
GeneOntologyMolecularFunctionsodium channel activity

SCN11A HCN1 SCN2A SCN4A

2.26e-0652364GO:0005272
GeneOntologyMolecularFunctionsymporter activity

SLC6A16 SLC1A2 SLC10A5 SLC1A6 SLC5A3

6.99e-06150365GO:0015293
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC1A2 SLC10A5 SLC1A6 SLC5A3

1.34e-0581364GO:0015370
GeneOntologyMolecularFunctionhigh-affinity L-glutamate transmembrane transporter activity

SLC1A2 SLC1A6

3.15e-055362GO:0005314
GeneOntologyMolecularFunctionglutamate:sodium symporter activity

SLC1A2 SLC1A6

3.15e-055362GO:0015501
GeneOntologyMolecularFunctionorganic acid:sodium symporter activity

SLC1A2 SLC10A5 SLC1A6

3.39e-0535363GO:0005343
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC1A2 SLC10A5 SLC1A6 SLC5A3

6.10e-05119364GO:0015294
GeneOntologyMolecularFunctioncalcium channel activity

CHRNA9 TRPC3 TRPC4 TRPC5

8.34e-05129364GO:0005262
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

CHRNA9 TRPC3 TRPC4 TRPC5

1.53e-04151364GO:0015085
GeneOntologyMolecularFunctionRNA-DNA hybrid ribonuclease activity

ERVK-8 ERVK-6

1.72e-0411362GO:0004523
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC6A16 SLC1A2 SLC10A5 SLC1A6 SLC5A3

1.79e-04296365GO:0015291
GeneOntologyMolecularFunctionRNA-directed DNA polymerase activity

ERVK-8 ERVK-6

2.84e-0414362GO:0003964
GeneOntologyMolecularFunctiongated channel activity

ANO9 CHRNA9 HCN1 TRPC3 SCN2A

3.13e-04334365GO:0022836
GeneOntologyMolecularFunctionL-glutamate transmembrane transporter activity

SLC1A2 SLC1A6

3.27e-0415362GO:0005313
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

ANO9 CHRNA9 HCN1 TRPC3

3.91e-04193364GO:0015276
GeneOntologyMolecularFunctionligand-gated channel activity

ANO9 CHRNA9 HCN1 TRPC3

4.23e-04197364GO:0022834
GeneOntologyMolecularFunctionadenylate cyclase activity

GUCY1A1 ADCY3

4.75e-0418362GO:0004016
GeneOntologyMolecularFunctionacidic amino acid transmembrane transporter activity

SLC1A2 SLC1A6

5.88e-0420362GO:0015172
GeneOntologyMolecularFunctionRNA stem-loop binding

ERVK-8 ERVK-6

6.49e-0421362GO:0035613
GeneOntologyMolecularFunctionamino acid:sodium symporter activity

SLC1A2 SLC1A6

7.81e-0423362GO:0005283
GeneOntologyMolecularFunctionalcohol binding

TRPC3 TRPC4 TRPC5

8.17e-04102363GO:0043178
GeneOntologyMolecularFunctioncyclase activity

GUCY1A1 ADCY3

8.51e-0424362GO:0009975
GeneOntologyMolecularFunctionphosphorus-oxygen lyase activity

GUCY1A1 ADCY3

9.24e-0425362GO:0016849
GeneOntologyMolecularFunctionendopeptidase activity

ERVK-8 ERVK-6 ERVK-19 ERVK-25 ERVK-9

9.84e-04430365GO:0004175
GeneOntologyMolecularFunctionamino acid:monoatomic cation symporter activity

SLC1A2 SLC1A6

1.24e-0329362GO:0005416
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC6A16 SLC1A2 SLC10A5 SLC1A6 SLC5A3

1.56e-03477365GO:0022804
GeneOntologyMolecularFunctionRNA endonuclease activity, producing 5'-phosphomonoesters

ERVK-8 ERVK-6

2.02e-0337362GO:0016891
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

CHRNA9 HCN1 TRPC3

2.03e-03140363GO:0099094
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC1A2 SLC10A5 SLC1A6 SLC5A3

2.04e-03301364GO:0022853
GeneOntologyMolecularFunctionDNA polymerase activity

ERVK-8 ERVK-6

2.13e-0338362GO:0034061
GeneOntologyMolecularFunctionneutral L-amino acid transmembrane transporter activity

SLC1A2 SLC1A6

2.48e-0341362GO:0015175
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

ANO9 SLC1A2 SLC1A6

2.52e-03151363GO:0008509
GeneOntologyMolecularFunctionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

ERVK-8 ERVK-6

3.11e-0346362GO:0016893
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR8S1 ADGRG1 OR51F2 GPR18 PTAFR OR6C4

4.62e-03884366GO:0004930
GeneOntologyMolecularFunctionpeptidase activity

ERVK-8 ERVK-6 ERVK-19 ERVK-25 ERVK-9

6.04e-03654365GO:0008233
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC1A2 SLC10A5 SLC1A6

6.09e-03207363GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC1A2 SLC10A5 SLC1A6

6.18e-03208363GO:0005342
GeneOntologyMolecularFunctionorganic hydroxy compound transmembrane transporter activity

SLC10A5 SLC5A3

7.07e-0370362GO:1901618
GeneOntologyMolecularFunctionL-amino acid transmembrane transporter activity

SLC1A2 SLC1A6

7.26e-0371362GO:0015179
GeneOntologyMolecularFunctionRNA endonuclease activity

ERVK-8 ERVK-6

8.92e-0379362GO:0004521
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR8S1 ADGRG1 OR51F2 GPR18 PTAFR CHRNA9 OR6C4

9.50e-031353367GO:0004888
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

SLC1A2 SLC1A6

1.54e-02105362GO:0015171
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC1A2 SLC10A5 SLC1A6

1.56e-02293363GO:0008514
GeneOntologyMolecularFunctionATPase binding

UBE4B TRPC5

1.62e-02108362GO:0051117
GeneOntologyBiologicalProcessmonoatomic ion transport

ANO9 SCN11A CHRNA9 SLC6A16 SLC1A2 SLC10A5 SLC1A6 HCN1 TRPC3 SCN2A TRPC4 TRPC5 SCN4A SLC5A3

3.00e-0813743614GO:0006811
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

ANO9 SCN11A CHRNA9 SLC6A16 SLC1A2 HCN1 TRPC3 SCN2A TRPC4 TRPC5 SCN4A SLC5A3

2.19e-0711153612GO:0034220
GeneOntologyBiologicalProcesssodium ion transport

SCN11A SLC6A16 SLC10A5 HCN1 SCN2A SCN4A SLC5A3

4.16e-07275367GO:0006814
GeneOntologyBiologicalProcesssyncytium formation

ERVK-8 ERVK-6 ERVK-19 ERVK-9 CYP19A1

4.53e-0789365GO:0006949
GeneOntologyBiologicalProcessmetal ion transport

SCN11A CHRNA9 SLC6A16 SLC10A5 HCN1 TRPC3 SCN2A TRPC4 TRPC5 SCN4A SLC5A3

6.47e-0710003611GO:0030001
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

ANO9 SCN11A CHRNA9 SLC6A16 HCN1 TRPC3 SCN2A TRPC4 TRPC5 SCN4A SLC5A3

7.64e-0710173611GO:0098660
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SCN11A SLC6A16 HCN1 SCN2A SCN4A SLC5A3

1.48e-06208366GO:0035725
GeneOntologyBiologicalProcessmembrane depolarization

SCN11A CHRNA9 HCN1 SCN2A SCN4A

2.08e-06121365GO:0051899
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

SCN11A CHRNA9 SLC6A16 HCN1 TRPC3 SCN2A TRPC4 TRPC5 SCN4A SLC5A3

2.67e-069223610GO:0098662
GeneOntologyBiologicalProcessmonoatomic cation transport

SCN11A CHRNA9 SLC6A16 SLC10A5 HCN1 TRPC3 SCN2A TRPC4 TRPC5 SCN4A SLC5A3

2.70e-0611573611GO:0006812
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

SCN11A CHRNA9 SLC6A16 HCN1 TRPC3 SCN2A TRPC4 TRPC5 SCN4A SLC5A3

3.23e-069423610GO:0098655
GeneOntologyBiologicalProcessregulation of membrane potential

SCN11A CHRNA9 SLC1A6 HCN1 SCN2A TRPC4 TRPC5 SCN4A

4.29e-06559368GO:0042391
GeneOntologyBiologicalProcessneuronal action potential

SCN11A HCN1 SCN2A SCN4A

4.33e-0663364GO:0019228
GeneOntologyBiologicalProcesscell-cell fusion

ERVK-8 ERVK-6 ERVK-19 ERVK-9

1.43e-0585364GO:0140253
GeneOntologyBiologicalProcesssyncytium formation by plasma membrane fusion

ERVK-8 ERVK-6 ERVK-19 ERVK-9

1.43e-0585364GO:0000768
GeneOntologyBiologicalProcessaction potential

SCN11A HCN1 SCN2A TRPC4 SCN4A

2.47e-05201365GO:0001508
GeneOntologyBiologicalProcessmembrane depolarization during action potential

SCN11A SCN2A SCN4A

3.35e-0536363GO:0086010
GeneOntologyBiologicalProcesstransmission of nerve impulse

SCN11A HCN1 SCN2A SCN4A

4.24e-05112364GO:0019226
GeneOntologyBiologicalProcessL-aspartate import across plasma membrane

SLC1A2 SLC1A6

4.42e-056362GO:0140009
GeneOntologyBiologicalProcessregulation of membrane hyperpolarization

HCN1 TRPC5

6.19e-057362GO:1902630
GeneOntologyBiologicalProcessphospholipid translocation

ANO9 SLC66A2 TRPC5

1.20e-0455363GO:0045332
GeneOntologyBiologicalProcesslipid translocation

ANO9 SLC66A2 TRPC5

1.56e-0460363GO:0034204
GeneOntologyBiologicalProcessL-aspartate transmembrane transport

SLC1A2 SLC1A6

1.61e-0411362GO:0070778
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

SCN11A SCN2A SCN4A

1.72e-0462363GO:0086002
GeneOntologyBiologicalProcessregulation of membrane lipid distribution

ANO9 SLC66A2 TRPC5

1.98e-0465363GO:0097035
GeneOntologyBiologicalProcessDNA integration

ERVK-8 ERVK-6

2.28e-0413362GO:0015074
GeneOntologyBiologicalProcesscirculatory system process

SCN11A PTAFR GUCY1A1 SLC1A2 SCN2A SCN4A SLC5A3

2.36e-04733367GO:0003013
GeneOntologyBiologicalProcessgastro-intestinal system smooth muscle contraction

SCN11A PTAFR

3.07e-0415362GO:0014831
GeneOntologyBiologicalProcessmuscle system process

SCN11A PTAFR GUCY1A1 TRPC3 SCN2A SCN4A

3.35e-04547366GO:0003012
GeneOntologyBiologicalProcessamino acid transport

SLC6A16 SLC1A2 SLC1A6 TRPC4

3.60e-04195364GO:0006865
GeneOntologyBiologicalProcessregulation of cytosolic calcium ion concentration

TRPC3 TRPC4 TRPC5

4.22e-0484363GO:0051480
GeneOntologyBiologicalProcesscardiac muscle cell action potential

SCN11A SCN2A SCN4A

4.68e-0487363GO:0086001
GeneOntologyBiologicalProcessL-glutamate import across plasma membrane

SLC1A2 SLC1A6

4.97e-0419362GO:0098712
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

OR8S1 ADGRG1 OR51F2 SCN11A GPR18 PTAFR ADCY3 OR6C4 CXCL17

5.12e-041395369GO:0007186
GeneOntologyBiologicalProcesscalcium ion transmembrane transport

SCN11A CHRNA9 TRPC3 TRPC4 TRPC5

5.61e-04392365GO:0070588
GeneOntologyBiologicalProcesscardiac muscle cell contraction

SCN11A SCN2A SCN4A

5.69e-0493363GO:0086003
GeneOntologyBiologicalProcesspositive regulation of cytosolic calcium ion concentration

CHRNA9 CXCL17 TRPC3 TRPC5

6.07e-04224364GO:0007204
GeneOntologyBiologicalProcessmembrane hyperpolarization

HCN1 TRPC5

6.09e-0421362GO:0060081
GeneOntologyBiologicalProcessmuscle contraction

SCN11A PTAFR GUCY1A1 SCN2A SCN4A

6.15e-04400365GO:0006936
GeneOntologyBiologicalProcessaspartate transmembrane transport

SLC1A2 SLC1A6

6.69e-0422362GO:0015810
GeneOntologyBiologicalProcessnegative regulation of leukocyte chemotaxis

GPR18 CYP19A1

7.32e-0423362GO:0002689
GeneOntologyBiologicalProcesscyclic nucleotide biosynthetic process

GUCY1A1 ADCY3

7.32e-0423362GO:0009190
GeneOntologyBiologicalProcessphospholipid transport

ANO9 SLC66A2 TRPC5

8.33e-04106363GO:0015914
GeneOntologyBiologicalProcesschronic inflammatory response

SCN11A CYP19A1

8.66e-0425362GO:0002544
GeneOntologyBiologicalProcessplasma membrane phospholipid scrambling

ANO9 TRPC5

9.38e-0426362GO:0017121
GeneOntologyBiologicalProcessC4-dicarboxylate transport

SLC1A2 SLC1A6

1.17e-0329362GO:0015740
GeneOntologyBiologicalProcessregulation of leukocyte migration

GPR18 PTAFR CXCL17 CYP19A1

1.17e-03267364GO:0002685
GeneOntologyBiologicalProcessresponse to nitrogen compound

ZNF106 SCN11A PTAFR UBE4B SLC1A2 HCN1 TRPC3 STT3B

1.31e-031272368GO:1901698
GeneOntologyBiologicalProcesschemosensory behavior

SCN11A ADCY3

1.33e-0331362GO:0007635
GeneOntologyBiologicalProcessactin-mediated cell contraction

SCN11A SCN2A SCN4A

1.40e-03127363GO:0070252
GeneOntologyBiologicalProcessdetection of stimulus

OR8S1 OR51F2 SCN11A CHRNA9 OR6C4 TRPC3

1.43e-03722366GO:0051606
GeneOntologyBiologicalProcesssmooth muscle contraction

SCN11A PTAFR GUCY1A1

1.60e-03133363GO:0006939
GeneOntologyBiologicalProcessL-glutamate transmembrane transport

SLC1A2 SLC1A6

1.70e-0335362GO:0015813
GeneOntologyBiologicalProcesslipid transport

ANO9 SLC66A2 SLC10A5 CYP19A1 TRPC5

1.75e-03506365GO:0006869
GeneOntologyBiologicalProcesscalcium ion transport

SCN11A CHRNA9 TRPC3 TRPC4 TRPC5

1.80e-03509365GO:0006816
GeneOntologyBiologicalProcessregulation of macrophage chemotaxis

CXCL17 CYP19A1

1.90e-0337362GO:0010758
GeneOntologyBiologicalProcessresponse to auditory stimulus

SCN11A CHRNA9

1.90e-0337362GO:0010996
GeneOntologyBiologicalProcessresponse to organophosphorus

PTAFR HCN1 TRPC3

1.93e-03142363GO:0046683
GeneOntologyBiologicalProcessregulation of leukocyte chemotaxis

GPR18 CXCL17 CYP19A1

1.97e-03143363GO:0002688
GeneOntologyBiologicalProcessresponse to abiotic stimulus

SCN11A PTAFR CHRNA9 UBE4B GUCY1A1 SLC1A2 TRPC3 SCN2A

2.02e-031361368GO:0009628
GeneOntologyBiologicalProcessregulation of muscle system process

PTAFR GUCY1A1 TRPC3 SCN4A

2.19e-03317364GO:0090257
GeneOntologyBiologicalProcesspositive regulation of Rho protein signal transduction

ADGRG1 GPR18

2.33e-0341362GO:0035025
GeneOntologyBiologicalProcessactin filament-based movement

SCN11A SCN2A SCN4A

2.39e-03153363GO:0030048
GeneOntologyBiologicalProcesscyclic purine nucleotide metabolic process

GUCY1A1 ADCY3

2.68e-0344362GO:0052652
GeneOntologyBiologicalProcesscyclic nucleotide metabolic process

GUCY1A1 ADCY3

2.80e-0345362GO:0009187
GeneOntologyBiologicalProcessorganophosphate ester transport

ANO9 SLC66A2 TRPC5

2.81e-03162363GO:0015748
GeneOntologyBiologicalProcesslipid localization

ANO9 SLC66A2 SLC10A5 CYP19A1 TRPC5

2.83e-03565365GO:0010876
GeneOntologyBiologicalProcessL-glutamate import

SLC1A2 SLC1A6

2.92e-0346362GO:0051938
GeneOntologyBiologicalProcessresponse to purine-containing compound

PTAFR HCN1 TRPC3

3.01e-03166363GO:0014074
GeneOntologyBiologicalProcesscardiac muscle contraction

SCN11A SCN2A SCN4A

3.06e-03167363GO:0060048
GeneOntologyBiologicalProcessDNA synthesis involved in DNA repair

ERVK-8 ERVK-6

3.18e-0348362GO:0000731
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR8S1 OR51F2 SCN11A CHRNA9 OR6C4

3.22e-03582365GO:0050906
GeneOntologyBiologicalProcessdetection of external stimulus

SCN11A CHRNA9 TRPC3

3.38e-03173363GO:0009581
GeneOntologyBiologicalProcessdetection of abiotic stimulus

SCN11A CHRNA9 TRPC3

3.49e-03175363GO:0009582
GeneOntologyCellularComponentcation channel complex

SCN11A HCN1 TRPC3 SCN2A TRPC4 TRPC5 SCN4A SLC5A3

6.60e-09235378GO:0034703
GeneOntologyCellularComponentmonoatomic ion channel complex

SCN11A CHRNA9 HCN1 TRPC3 SCN2A TRPC4 TRPC5 SCN4A SLC5A3

1.50e-08378379GO:0034702
GeneOntologyCellularComponenttransmembrane transporter complex

SCN11A CHRNA9 HCN1 TRPC3 SCN2A TRPC4 TRPC5 SCN4A SLC5A3

2.39e-07523379GO:1902495
GeneOntologyCellularComponenttransporter complex

SCN11A CHRNA9 HCN1 TRPC3 SCN2A TRPC4 TRPC5 SCN4A SLC5A3

3.65e-07550379GO:1990351
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN11A SCN2A SCN4A

3.41e-0617373GO:0001518
GeneOntologyCellularComponentmembrane protein complex

SCN11A CHRNA9 SLC1A2 SLC1A6 HCN1 TRPC3 SCN2A TRPC4 TRPC5 STT3B SCN4A SLC5A3

6.02e-0614983712GO:0098796
GeneOntologyCellularComponentsodium channel complex

SCN11A SCN2A SCN4A

1.81e-0529373GO:0034706
GeneOntologyCellularComponentpresynaptic membrane

SCN11A SLC1A2 SLC1A6 HCN1 SCN2A

1.21e-04277375GO:0042734
GeneOntologyCellularComponentsynaptic membrane

SCN11A CHRNA9 SLC1A2 SLC1A6 HCN1 SCN2A

5.11e-04583376GO:0097060
GeneOntologyCellularComponentpresynapse

SCN11A SLC1A2 SLC1A6 HCN1 CYP19A1 SCN2A TRPC5

8.11e-04886377GO:0098793
GeneOntologyCellularComponentaxon

SCN11A SLC1A2 HCN1 CYP19A1 SCN2A TRPC5 SCN4A

8.38e-04891377GO:0030424
GeneOntologyCellularComponentastrocyte projection

ADGRG1 SLC1A2

8.91e-0425372GO:0097449
GeneOntologyCellularComponentplasma membrane protein complex

SCN11A CHRNA9 HCN1 SCN2A SCN4A SLC5A3

2.36e-03785376GO:0098797
GeneOntologyCellularComponentglutamatergic synapse

SCN11A GUCY1A1 SLC1A2 SLC1A6 HCN1 SCN2A

2.89e-03817376GO:0098978
GeneOntologyCellularComponentglial cell projection

ADGRG1 SLC1A2

3.13e-0347372GO:0097386
GeneOntologyCellularComponentdistal axon

SCN11A HCN1 CYP19A1 TRPC5

7.10e-03435374GO:0150034
GeneOntologyCellularComponentcalcium channel complex

TRPC4 TRPC5

7.40e-0373372GO:0034704
GeneOntologyCellularComponentdendritic shaft

SLC1A2 HCN1

7.60e-0374372GO:0043198
GeneOntologyCellularComponentneuron projection terminus

SLC1A2 HCN1 CYP19A1

8.03e-03233373GO:0044306
GeneOntologyCellularComponentneuron projection membrane

SLC1A2 HCN1

9.26e-0382372GO:0032589
HumanPhenoStatus epilepticus without prominent motor symptoms

SLC1A2 HCN1 SCN2A

3.67e-0527133HP:0031475
MousePhenoabnormal nervous system electrophysiology

SCN11A CHRNA9 SLC1A6 HCN1 TRPC3 SCN2A TRPC4 TRPC5 SLC5A3

7.55e-10329229MP:0002272
MousePhenoabnormal action potential

SCN11A CHRNA9 HCN1 SCN2A TRPC5

1.67e-06133225MP:0005402
MousePhenoabnormal excitatory postsynaptic currents

TRPC3 SCN2A TRPC4 TRPC5

3.24e-05119224MP:0002910
DomainIon_trans_dom

SCN11A HCN1 TRPC3 SCN2A TRPC4 TRPC5 SCN4A

9.82e-10114337IPR005821
DomainIon_trans

SCN11A HCN1 TRPC3 SCN2A TRPC4 TRPC5 SCN4A

9.82e-10114337PF00520
DomainTRP_dom

TRPC3 TRPC4 TRPC5

1.00e-076333IPR013555
DomainTRP_2

TRPC3 TRPC4 TRPC5

1.00e-076333PF08344
DomainTRPC_channel

TRPC3 TRPC4 TRPC5

1.75e-077333IPR002153
DomainNa_channel_asu

SCN11A SCN2A SCN4A

5.98e-0710333IPR001696
DomainNa_trans_assoc

SCN11A SCN2A SCN4A

5.98e-0710333IPR010526
DomainNa_trans_assoc

SCN11A SCN2A SCN4A

5.98e-0710333PF06512
DomainTRP_channel

TRPC3 TRPC4 TRPC5

8.21e-0711333IPR004729
DomainNa-dicarboxylate_symporter

SLC1A2 SLC1A6

6.32e-057332IPR001991
DomainSDF

SLC1A2 SLC1A6

6.32e-057332PF00375
Domain-

SLC1A2 SLC1A6

6.32e-0573321.10.3860.10
DomainNA_DICARBOXYL_SYMP_1

SLC1A2 SLC1A6

6.32e-057332PS00713
DomainNA_DICARBOXYL_SYMP_2

SLC1A2 SLC1A6

6.32e-057332PS00714
DomainNa-dicarboxylate_symporter_CS

SLC1A2 SLC1A6

6.32e-057332IPR018107
DomainChannel_four-helix_dom

SCN11A SCN2A SCN4A

1.38e-0457333IPR027359
Domain-

SCN11A SCN2A SCN4A

1.38e-04573331.20.120.350
DomainA/G_cyclase_CS

GUCY1A1 ADCY3

4.05e-0417332IPR018297
DomainNucleotide_cyclase

GUCY1A1 ADCY3

4.55e-0418332IPR029787
Domain-

GUCY1A1 ADCY3

4.55e-04183323.30.70.1230
DomainGUANYLATE_CYCLASE_2

GUCY1A1 ADCY3

5.08e-0419332PS50125
DomainGUANYLATE_CYCLASE_1

GUCY1A1 ADCY3

5.08e-0419332PS00452
DomainA/G_cyclase

GUCY1A1 ADCY3

5.08e-0419332IPR001054
DomainCYCc

GUCY1A1 ADCY3

5.08e-0419332SM00044
DomainGuanylate_cyc

GUCY1A1 ADCY3

5.08e-0419332PF00211
DomainGPCR_Rhodpsn_7TM

OR8S1 OR51F2 GPR18 PTAFR OR6C4

6.04e-03670335IPR017452
Domain7tm_1

OR8S1 OR51F2 GPR18 PTAFR OR6C4

6.31e-03677335PF00001
DomainG_PROTEIN_RECEP_F1_1

OR8S1 OR51F2 GPR18 PTAFR OR6C4

6.62e-03685335PS00237
DomainG_PROTEIN_RECEP_F1_2

OR8S1 OR51F2 GPR18 PTAFR OR6C4

6.87e-03691335PS50262
DomainGPCR_Rhodpsn

OR8S1 OR51F2 GPR18 PTAFR OR6C4

6.91e-03692335IPR000276
DomainAnk

TRPC3 TRPC4 TRPC5

7.48e-03228333PF00023
DomainIQ

SCN2A SCN4A

8.99e-0381332SM00015
Domain-

TRPC3 TRPC4 TRPC5

9.41e-032483331.25.40.20
DomainANK

TRPC3 TRPC4 TRPC5

9.72e-03251333SM00248
DomainANK_REPEAT

TRPC3 TRPC4 TRPC5

9.93e-03253333PS50088
DomainAnkyrin_rpt-contain_dom

TRPC3 TRPC4 TRPC5

1.00e-02254333IPR020683
DomainANK_REP_REGION

TRPC3 TRPC4 TRPC5

1.00e-02254333PS50297
DomainAnkyrin_rpt

TRPC3 TRPC4 TRPC5

1.09e-02262333IPR002110
DomainIQ_motif_EF-hand-BS

SCN2A SCN4A

1.10e-0290332IPR000048
DomainIQ

SCN2A SCN4A

1.17e-0293332PS50096
PathwayBIOCARTA_RACC_PATHWAY

GUCY1A1 TRPC3 TRPC4 TRPC5

1.22e-0815264M22002
PathwayREACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN_1_SIGNALING

TRPC3 TRPC4 TRPC5

6.63e-0710263M27330
PathwayREACTOME_TRP_CHANNELS

TRPC3 TRPC4 TRPC5

1.77e-0528263MM14943
PathwayREACTOME_TRP_CHANNELS

TRPC3 TRPC4 TRPC5

1.77e-0528263M27241
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SCN11A SCN2A SCN4A

2.42e-0531263M877
PathwayREACTOME_PHASE_0_RAPID_DEPOLARISATION

SCN11A SCN2A SCN4A

2.67e-0532263M27455
PathwayREACTOME_STIMULI_SENSING_CHANNELS

ANO9 TRPC3 TRPC4 TRPC5

3.04e-0599264MM14910
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ANO9 SLC1A2 ADCY3 SLC1A6 TRPC3 TRPC4 TRPC5 SLC5A3

3.58e-05736268M27287
PathwayREACTOME_STIMULI_SENSING_CHANNELS

ANO9 TRPC3 TRPC4 TRPC5

3.97e-05106264M27200
PathwayREACTOME_NETRIN_1_SIGNALING

TRPC3 TRPC4 TRPC5

7.02e-0544263M875
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ANO9 SLC1A2 SLC1A6 TRPC3 TRPC4 TRPC5 SLC5A3

1.75e-04681267MM14985
PathwayREACTOME_ION_CHANNEL_TRANSPORT

ANO9 TRPC3 TRPC4 TRPC5

2.83e-04176264MM15718
PathwayREACTOME_NEURONAL_SYSTEM

CHRNA9 SLC1A2 ADCY3 SLC1A6 HCN1

3.21e-04335265MM14503
PathwayREACTOME_ION_CHANNEL_TRANSPORT

ANO9 TRPC3 TRPC4 TRPC5

3.29e-04183264M997
PathwayREACTOME_MUSCLE_CONTRACTION

SCN11A GUCY1A1 SCN2A SCN4A

4.87e-04203264M5485
PathwayREACTOME_NERVOUS_SYSTEM_DEVELOPMENT

SCN11A TRPC3 SCN2A TRPC4 TRPC5 SCN4A

5.14e-04575266M29853
PathwayREACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES

CHRNA9 SLC1A2 ADCY3 SLC1A6

5.63e-04211264MM14502
PathwayREACTOME_NEURONAL_SYSTEM

CHRNA9 SLC1A2 ADCY3 SLC1A6 HCN1

8.15e-04411265M735
PathwayREACTOME_SENSORY_PERCEPTION

OR8S1 OR51F2 CHRNA9 ADCY3 OR6C4 SCN2A

8.74e-04636266M41834
PathwayREACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE

SLC1A2 SLC1A6

8.81e-0424262MM14834
PathwayREACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE

SLC1A2 SLC1A6

8.81e-0424262M630
PathwayWP_DRAVET_SYNDROME

HCN1 SCN2A

1.20e-0328262M45519
PathwayREACTOME_L1CAM_INTERACTIONS

SCN11A SCN2A SCN4A

1.39e-03121263M872
PathwayREACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES

CHRNA9 SLC1A2 ADCY3 SLC1A6

1.41e-03270264M15514
PathwayREACTOME_CARDIAC_CONDUCTION

SCN11A SCN2A SCN4A

1.71e-03130263M27454
PathwayWP_NEUROINFLAMMATION_AND_GLUTAMATERGIC_SIGNALING

SLC1A2 ADCY3 SLC1A6

2.11e-03140263M42572
PathwayREACTOME_NEUROTRANSMITTER_RELEASE_CYCLE

SLC1A2 SLC1A6

3.95e-0351262MM14499
PathwayREACTOME_NEUROTRANSMITTER_RELEASE_CYCLE

SLC1A2 SLC1A6

3.95e-0351262M4281
PathwayWP_PHOSPHODIESTERASES_IN_NEURONAL_FUNCTION

GUCY1A1 ADCY3

4.57e-0355262M39763
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR8S1 OR51F2 ADCY3 OR6C4

5.28e-03389264M14091
Pubmed

Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.

ERVK-8 ERVK-6 ERVK-19 ERVK-9

5.33e-101237414557543
Pubmed

Cyclic-Nucleotide- and HCN-Channel-Mediated Phototransduction in Intrinsically Photosensitive Retinal Ganglion Cells.

HCN1 TRPC3 TRPC4 TRPC5

6.40e-092137430270038
Pubmed

Formation of novel TRPC channels by complex subunit interactions in embryonic brain.

TRPC3 TRPC4 TRPC5

1.11e-08537312857742
Pubmed

Enhanced capacitative calcium entry and TRPC channel gene expression in human LES smooth muscle.

TRPC3 TRPC4 TRPC5

1.11e-08537312736151
Pubmed

Calcium Channels Formed by Mammalian Trp Homologues.

TRPC3 TRPC4 TRPC5

2.21e-08637311390792
Pubmed

trp, a novel mammalian gene family essential for agonist-activated capacitative Ca2+ entry.

TRPC3 TRPC4 TRPC5

2.21e-0863738646775
Pubmed

Transient receptor potential channels and their role in modulating radial glial-neuronal interaction: a signaling pathway involving mGluR5.

TRPC3 TRPC4 TRPC5

2.21e-08637325347706
Pubmed

TRPM4 Conductances in Thalamic Reticular Nucleus Neurons Generate Persistent Firing during Slow Oscillations.

TRPC3 TRPC4 TRPC5

2.21e-08637332414784
Pubmed

Human endogenous retrovirus HERV-K(HML-2) proviruses with Rec protein coding capacity and transcriptional activity.

ERVK-6 ERVK-19 ERVK-9

2.21e-08637315063128
Pubmed

MxA, a member of the dynamin superfamily, interacts with the ankyrin-like repeat domain of TRPC.

TRPC3 TRPC4 TRPC5

3.87e-08737315757897
Pubmed

TRPC absence induces pro-inflammatory macrophage polarization to promote obesity and exacerbate colorectal cancer.

TRPC3 TRPC4 TRPC5

3.87e-08737338835669
Pubmed

Mechanism of stretch-induced activation of the mechanotransducer zyxin in vascular cells.

TRPC3 TRPC4 TRPC5

3.87e-08737323233529
Pubmed

RNA-seq analysis reveals TRPC genes to impact an unexpected number of metabolic and regulatory pathways.

TRPC3 TRPC4 TRPC5

3.87e-08737332350291
Pubmed

TRPC absence induces pro-inflammatory macrophages and gut microbe disorder, sensitizing mice to colitis.

TRPC3 TRPC4 TRPC5

3.87e-08737336592529
Pubmed

Functional role of TRPC proteins in vivo: lessons from TRPC-deficient mouse models.

TRPC3 TRPC4 TRPC5

3.87e-08737315336983
Pubmed

Subunit composition, molecular environment, and activation of native TRPC channels encoded by their interactomes.

TRPC3 TRPC4 TRPC5

3.87e-08737336257322
Pubmed

A revised nomenclature for transcribed human endogenous retroviral loci.

ERVK-8 ERVK-6 ERVK-19 ERVK-25 ERVK-9

5.27e-089437521542922
Pubmed

Subunit composition of mammalian transient receptor potential channels in living cells.

TRPC3 TRPC4 TRPC5

6.18e-08837312032305
Pubmed

Association of immunophilins with mammalian TRPC channels.

TRPC3 TRPC4 TRPC5

6.18e-08837315199065
Pubmed

Metabolism regulates the spontaneous firing of substantia nigra pars reticulata neurons via KATP and nonselective cation channels.

TRPC3 TRPC4 TRPC5

6.18e-08837325471572
Pubmed

Identification of common binding sites for calmodulin and inositol 1,4,5-trisphosphate receptors on the carboxyl termini of trp channels.

TRPC3 TRPC4 TRPC5

9.27e-08937311290752
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN11A SCN2A SCN4A

9.27e-08937316382098
Pubmed

Homer binds TRPC family channels and is required for gating of TRPC1 by IP3 receptors.

TRPC3 TRPC4 TRPC5

9.27e-08937314505576
Pubmed

Cellular subtype distribution and developmental regulation of TRPC channel members in the mouse dorsal root ganglion.

TRPC3 TRPC4 TRPC5

9.27e-08937317480026
Pubmed

Heterogeneous distribution of TRPC proteins in the embryonic cortex.

TRPC3 TRPC4 TRPC5

1.32e-071037318989690
Pubmed

The leak channel NALCN controls tonic firing and glycolytic sensitivity of substantia nigra pars reticulata neurons.

TRPC3 TRPC4 TRPC5

1.32e-071037327177420
Pubmed

Melanopsin signalling in mammalian iris and retina.

TRPC3 TRPC4 TRPC5

3.15e-071337322051675
Pubmed

Dynamic regulation of sarcoplasmic reticulum Ca(2+) stores by stromal interaction molecule 1 and sarcolipin during muscle differentiation.

TRPC3 TRPC4 TRPC5

7.46e-071737322411552
Pubmed

Downregulation of TRPC4 and TRPC5 Inhibits Smooth Muscle Cell Proliferation without Affecting Endothelial Cell Proliferation.

TRPC4 TRPC5

1.10e-06237234899056
Pubmed

Differential distribution of TRP Ca2+ channel isoforms in mouse brain.

TRPC3 TRPC4

1.10e-0623729512398
Pubmed

Corticolimbic expression of TRPC4 and TRPC5 channels in the rodent brain.

TRPC4 TRPC5

1.10e-06237217593972
Pubmed

TRPC3 and TRPC4 associate to form a redox-sensitive cation channel. Evidence for expression of native TRPC3-TRPC4 heteromeric channels in endothelial cells.

TRPC3 TRPC4

1.10e-06237216537542
Pubmed

Selective Gαi subunits as novel direct activators of transient receptor potential canonical (TRPC)4 and TRPC5 channels.

TRPC4 TRPC5

1.10e-06237222457348
Pubmed

Conserved gating elements in TRPC4 and TRPC5 channels.

TRPC4 TRPC5

1.10e-06237223677990
Pubmed

Acute Treatment with a Novel TRPC4/C5 Channel Inhibitor Produces Antidepressant and Anxiolytic-Like Effects in Mice.

TRPC4 TRPC5

1.10e-06237226317356
Pubmed

Involvement of TRPC4 and 5 Channels in Persistent Firing in Hippocampal CA1 Pyramidal Cells.

TRPC4 TRPC5

1.10e-06237232033274
Pubmed

Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.

ERVK-6 ERVK-19

1.10e-0623729060628
Pubmed

The first ankyrin-like repeat is the minimum indispensable key structure for functional assembly of homo- and heteromeric TRPC4/TRPC5 channels.

TRPC4 TRPC5

1.10e-06237217624425
Pubmed

Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses.

ERVK-6 ERVK-19

1.10e-0623729460924
Pubmed

A novel capacitative calcium entry channel expressed in excitable cells.

TRPC4 TRPC5

1.10e-0623729687496
Pubmed

TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A.

TRPC4 TRPC5

1.10e-06237230038709
Pubmed

Genetic mapping of mouse transient receptor potential (Trrp) genes responsible for capacitative calcium entry channels to chromosomes 3, 7, 9, and X.

TRPC3 TRPC4 TRPC5

2.21e-06243739722956
Pubmed

Mapping the expression of transient receptor potential channels across murine placental development.

TRPC3 TRPC4 TRPC5

2.21e-062437333884443
Pubmed

International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels.

TRPC3 TRPC4 TRPC5

2.51e-062537316382100
Pubmed

TRPC1/4/5 channels contribute to morphine-induced analgesic tolerance and hyperalgesia by enhancing spinal synaptic potentiation and structural plasticity.

TRPC4 TRPC5

3.30e-06337232359120
Pubmed

Heteromeric channels formed by TRPC1, TRPC4 and TRPC5 define hippocampal synaptic transmission and working memory.

TRPC4 TRPC5

3.30e-06337228790178
Pubmed

Differential PI(4,5)P2 sensitivities of TRPC4, C5 homomeric and TRPC1/4, C1/5 heteromeric channels.

TRPC4 TRPC5

3.30e-06337230755645
Pubmed

Enhanced expression of transient receptor potential channels in idiopathic pulmonary arterial hypertension.

TRPC3 TRPC4

3.30e-06337215358862
Pubmed

A functional link between store-operated and TRPC channels revealed by the 3,5-bis(trifluoromethyl)pyrazole derivative, BTP2.

TRPC3 TRPC5

3.30e-06337215647288
Pubmed

Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels.

TRPC4 TRPC5

3.30e-06337228325835
Pubmed

Inositol 1,4,5-trisphosphate signaling maintains the activity of glutamate uptake in Bergmann glia.

SLC1A2 SLC1A6

3.30e-06337220958799
Pubmed

Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.

ERVK-6 ERVK-19

3.30e-06337210516026
Pubmed

Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirus.

ERVK-6 ERVK-9

3.30e-0633729971820
Pubmed

Transient Receptor Potential C 1/4/5 Is a Determinant of MTI-101 Induced Calcium Influx and Cell Death in Multiple Myeloma.

TRPC4 TRPC5

3.30e-06337234199280
Pubmed

Polymorphisms of ESR1, UGT1A1, HCN1, MAP3K1 and CYP2B6 are associated with the prognosis of hormone receptor-positive early breast cancer.

HCN1 CYP19A1

3.30e-06337228178648
Pubmed

Dual action of the Gαq-PLCβ-PI(4,5)P2 pathway on TRPC1/4 and TRPC1/5 heterotetramers.

TRPC4 TRPC5

3.30e-06337230108272
Pubmed

A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.

TRPC3 TRPC4 TRPC5

5.92e-063337319834762
Pubmed

Interaction with dopamine D2 receptor enhances expression of transient receptor potential channel 1 at the cell surface.

TRPC4 TRPC5

6.60e-06437218261457
Pubmed

Structure and functional expression of the cloned mouse neuronal high-affinity glutamate transporter.

SLC1A2 SLC1A6

6.60e-0643729379843
Pubmed

The phospholipid-binding protein SESTD1 is a novel regulator of the transient receptor potential channels TRPC4 and TRPC5.

TRPC4 TRPC5

6.60e-06437220164195
Pubmed

Molecular identification and localization of Trp homologues, putative calcium channels, in pregnant human uterus.

TRPC3 TRPC4

6.60e-06437212356946
Pubmed

NMDA receptor-dependent synaptic activation of TRPC channels in olfactory bulb granule cells.

TRPC4 TRPC5

6.60e-06437222539836
Pubmed

The contribution of TRPC1, TRPC3, TRPC5 and TRPC6 to touch and hearing.

TRPC3 TRPC5

6.60e-06437226520460
Pubmed

Phospholipase cgamma1 is required for activation of store-operated channels in human keratinocytes.

TRPC3 TRPC4

6.60e-06437215654973
Pubmed

Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.

ERVK-6 ERVK-19

6.60e-0643727983737
Pubmed

Impact of Reduced Cerebellar EAAT Expression on Purkinje Cell Firing Pattern of NPC1-deficient Mice.

SLC1A2 SLC1A6

6.60e-06437229463856
Pubmed

Canonical transient receptor channel 5 (TRPC5) and TRPC1/4 contribute to seizure and excitotoxicity by distinct cellular mechanisms.

TRPC4 TRPC5

6.60e-06437223188715
Pubmed

TRPC1- and TRPC3-dependent Ca2+ signaling in mouse cortical astrocytes affects injury-evoked astrogliosis in vivo.

TRPC3 TRPC5

6.60e-06437228636132
Pubmed

Transient Receptor Potential Canonical 5-Scramblase Signaling Complex Mediates Neuronal Phosphatidylserine Externalization and Apoptosis.

TRPC4 TRPC5

6.60e-06437232110987
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

TRPC3 TRPC4 TRPC5

9.11e-063837330786075
Pubmed

Distinct calcium channels regulate responses of primary B lymphocytes to B cell receptor engagement and mechanical stimuli.

TRPC3 TRPC4

1.10e-05537215611229
Pubmed

Quantitation of HERV-K env gene expression and splicing in human breast cancer.

ERVK-6 ERVK-19

1.10e-05537212629516
Pubmed

Changes in expression and distribution of the glutamate transporter EAAT4 in developing mouse Purkinje cells.

SLC1A2 SLC1A6

1.10e-0553729129177
Pubmed

Store-operated Ca2+ entry and Ca2+ responses to hypothalamic releasing hormones in anterior pituitary cells from Orai1-/- and heptaTRPC knockout mice.

TRPC3 TRPC5

1.10e-05537230452936
Pubmed

Association of mammalian trp4 and phospholipase C isozymes with a PDZ domain-containing protein, NHERF.

TRPC4 TRPC5

1.10e-05537210980202
Pubmed

TRUSS, TNF-R1, and TRPC ion channels synergistically reverse endoplasmic reticulum Ca2+ storage reduction in response to m1 muscarinic acetylcholine receptor signaling.

TRPC4 TRPC5

1.10e-05537220458742
Pubmed

TRPC3 channels are required for synaptic transmission and motor coordination.

TRPC3 TRPC4

1.10e-05537218701065
Pubmed

Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.

SCN2A SCN4A

1.10e-05537217724025
Pubmed

Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development.

TRPC3 TRPC4 TRPC5

1.42e-054437319322198
Pubmed

TRPC channels regulate Ca2+-signaling and short-term plasticity of fast glutamatergic synapses.

TRPC4 TRPC5

1.65e-05637231536487
Pubmed

Are voltage-dependent ion channels involved in the endothelial cell control of vasomotor tone?

SCN11A SCN2A

1.65e-05637217513486
Pubmed

TRPC proteins contribute to development of diabetic retinopathy and regulate glyoxalase 1 activity and methylglyoxal accumulation.

TRPC4 TRPC5

1.65e-05637229373286
Pubmed

Hypothalamic warm-sensitive neurons require TRPC4 channel for detecting internal warmth and regulating body temperature in mice.

TRPC4 TRPC5

1.65e-05637236476978
Pubmed

Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.

SCN2A SCN4A

3.95e-05937215746173
Pubmed

Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins.

ERVK-6 ERVK-19

4.93e-051037212970426
Pubmed

Hyperpolarization-activated cyclic nucleotide-gated channels in olfactory sensory neurons regulate axon extension and glomerular formation.

ADCY3 HCN1

1.15e-041537221147989
Pubmed

Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.

ERVK-25 ERVK-9

1.67e-041837218664271
Pubmed

SHARPIN negatively associates with TRAF2-mediated NFκB activation.

ZNF106 SCN11A

1.86e-041937221829440
Pubmed

Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis.

CHRNA9 SLC1A2 SLC1A6

2.72e-0411837319156168
Pubmed

Runx1 determines nociceptive sensory neuron phenotype and is required for thermal and neuropathic pain.

SCN11A TRPC3

2.75e-042337216446141
Pubmed

An introduction to TRP channels.

TRPC3 TRPC5

3.80e-042737216460286
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

SCN11A HCN1 SCN4A

4.39e-0413937316985003
Pubmed

Direction selectivity in the retina is established independent of visual experience and cholinergic retinal waves.

SCN11A TRPC3

6.41e-043537218498732
Pubmed

Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons.

SCN11A TRPC3

7.16e-043737218498735
Pubmed

The genetic program of hematopoietic stem cells.

ADGRG1 ZNF106

7.56e-043837210834841
InteractionTRPC4 interactions

TRPC3 TRPC4 TRPC5

5.17e-0623303int:TRPC4
InteractionTRPC5 interactions

TRPC3 TRPC4 TRPC5

5.90e-0624303int:TRPC5
InteractionTRPC6 interactions

TRPC3 TRPC4 TRPC5 STT3B

6.44e-0682304int:TRPC6
InteractionTRPC1 interactions

TRPC3 TRPC4 TRPC5

1.06e-0529303int:TRPC1
InteractionTRPC3 interactions

TRPC3 TRPC4 TRPC5

1.58e-0533303int:TRPC3
InteractionITPR1 interactions

UBE4B TRPC3 TRPC4 TRPC5

5.46e-05141304int:ITPR1
InteractionMX1 interactions

TRPC3 TRPC4 TRPC5

9.62e-0560303int:MX1
GeneFamilySodium voltage-gated channel alpha subunits

SCN11A SCN2A SCN4A

3.44e-0793031203
GeneFamilyTransient receptor potential cation channels

TRPC3 TRPC4 TRPC5

1.31e-0528303249
GeneFamilySolute carriers

SLC6A16 SLC1A2 SLC10A5 SLC1A6 SLC5A3

4.41e-04395305752
CoexpressionAtlaskidney_adult_RenMedVasc_Tie2_k-means-cluster#1_top-relative-expression-ranked_1000

ADGRG1 RNF13 SLC5A3

7.73e-0563283gudmap_kidney_adult_RenMedVasc_Tie2_k1_1000
CoexpressionAtlasBM Top 100 - cerebral cortex

SLC1A2 HCN1 SCN2A

1.15e-0472283BM Top 100 - cerebral cortex
CoexpressionAtlasBM Top 100 - occipital lobe

SLC1A2 HCN1 SCN2A

1.20e-0473283BM Top 100 - occipital lobe
CoexpressionAtlasBM Top 100 - parietal lobe

SLC1A2 HCN1 SCN2A

1.30e-0475283BM Top 100 - parietal lobe
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLC6A16 ADCY3 TRPC3 TRPC4

8.34e-06181324451b87ac95154bb80018b8dd245b4a6389d81411
ToppCellCOVID-19-Fibroblasts-Pericytes|COVID-19 / group, cell type (main and fine annotations)

GUCY1A1 ADCY3 TRPC3 TRPC4

9.09e-061853244905adaeeffd353e089578e5ea614437dbe794e6
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC1A6 HCN1 TRPC3 TRPC5

9.69e-061883241efbc99bcd6542e5d9fa91edb7c4295167914786
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GUCY1A1 ADCY3 TRPC3 TRPC4

1.01e-051903245681c211baeed4af82a2bbc13420f6a7b487581c
ToppCellCOVID-19-lung-Pericytes/_Smooth_Muscle|COVID-19 / Disease (COVID-19 only), tissue and cell type

GUCY1A1 ADCY3 TRPC3 TRPC4

1.14e-05196324754a3613340932563cd8424d775e18b93c3a1aaa
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|367C / Donor, Lineage, Cell class and subclass (all cells)

ANO9 URB2 GPR18

1.12e-04131323cc5b5afab8622e98f673fa116a226d930c295327
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

OR8S1 CHRNA9 CXCL17

1.55e-04146323281144e293e8c93a425c2606d2188cb2838e667f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY3 TRPC3 TRPC4

1.81e-04154323b6e982e341c6cfb6ff80a318078fcb10c36d182f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY3 TRPC3 TRPC4

1.81e-04154323d76fd51a4587decbfe1dde1c8a9b880c5fa18e4a
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR18 HCN1 TRPC4

1.85e-0415532372a19a9ecfd13f6769c4b447d3ce01a855ec6ec7
ToppCellStriatum-Neuronal-Inhibitory|Striatum / BrainAtlas - Mouse McCarroll V32

SLC1A6 HCN1 TRPC5

1.92e-04157323c41ff3fe9de7187575114febfe9bd8733366fb8a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY3 SLC10A5 TRPC4

2.10e-0416232382e782096f89cd03d1fdf599ba727d6f23e35e2d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY3 SLC10A5 TRPC4

2.10e-041623236bed33b17b59812646dc6a29c1d87413bad86c11
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY3 SLC10A5 TRPC4

2.10e-04162323502ed67f6a572f10ac6e22948a1747d8214eb974
ToppCell10x5'v1-week_17-19-Hematopoietic-HSC/MPP_and_pro|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ADGRG1 CHRNA9 GUCY1A1

2.14e-04163323edca1d1a345109dbdeb7ee5464faefab1993fdb2
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY3 TRPC3 TRPC4

2.22e-041653239de841c1c95967c562720feba930246debc626fd
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY3 TRPC3 TRPC4

2.22e-04165323a612a7d3a5415ecacc3df8fbff0ce498f982aad0
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY3 TRPC3 TRPC4

2.22e-04165323cdc94a640ec01c6892521bcd6f0ee0a66ff23866
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-Granular_Neuron_CB_Gabra6|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HCN1 TRPC3 SCN2A

2.26e-04166323ec7bd549bda5f18aca8aebce5ba479a81abbbeda
ToppCell10x_3'_v3-blood_(10x_3'_v3)-hematologic-hematopoietic_progenitor-hematopoietic_stem_cell|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

GUCY1A1 SLC10A5 SLC1A6

2.43e-041703235bb577e2c4bd275fbe4ee23ff8c007b2fcb90e56
ToppCellwk_08-11-Epithelial-Airway_epithelial_progenitor-epi-prox-progenitor-MUC5AC+ASCL1+_intermediate_|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ADGRG1 ANO9 CXCL17

2.43e-04170323d6e244725b21592c6056b9c443aac090f1eae836
ToppCellControl-Fibroblasts-Pericytes|Control / group, cell type (main and fine annotations)

ADCY3 TRPC3 TRPC4

2.47e-04171323080003f698f867935c2bfc55d241d3650f45a0ab
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ANO9 URB2 ADCY3

2.51e-04172323da959c1abadafd79b7a0088a25eb8ef8efa3a0c2
ToppCellfacs-Heart-LV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GUCY1A1 ADCY3 TRPC3

2.55e-04173323d78397e65e997ddb995111a810f0e2a4f67d0765
ToppCellAdult-Mesenchymal-pericyte_cell-D175|Adult / Lineage, Cell type, age group and donor

ADCY3 TRPC3 TRPC4

2.55e-04173323fd6653d6be9ca6ac36798590694efe03cb758c67
ToppCellfacs-Heart-LV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GUCY1A1 ADCY3 TRPC3

2.55e-041733233c852ffe22f4a5b632463086b08c669310684e80
ToppCellfacs-Heart-RV-24m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GUCY1A1 ADCY3 TRPC3

2.64e-04175323bfac175b79bb7d3d81074a2407c206a7647ee75d
ToppCellfacs-Heart-RV-24m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GUCY1A1 ADCY3 TRPC3

2.64e-04175323c94fb35bbac95123201ca87ca835aecaefc0c490
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GUCY1A1 ADCY3 TRPC4

2.73e-04177323a8625d14682183cf77cb51eaf11bc15a3528f586
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GUCY1A1 ADCY3 TRPC4

2.73e-041773233645e2f4a48283f290f85c49c3e79e3f58ac9aa6
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADCY3 TRPC3 TRPC4

2.73e-04177323452ec2df36c6d656a7cdadc55be545ccdb146a29
ToppCelldroplet-Lung-LUNG-30m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GUCY1A1 SLC1A6 TRPC3

2.82e-04179323bfc226bcf0b93525992344f968268a261d86fcbf
ToppCellCOVID-19-kidney-vSMC/Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADCY3 TRPC3 TRPC4

2.82e-04179323111b1084f73306bdeffaaf240e7dbb4f5bf33de1
ToppCelldroplet-Lung-LUNG-30m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GUCY1A1 SLC1A6 TRPC3

2.82e-0417932336ad18f52e175ab636ceaa3be81212fa362c96c1
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADCY3 TRPC3 TRPC4

2.82e-04179323dc6cd46fa652b296ddbc41855f6377946d0a4cdc
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC1A6 HCN1 TRPC3

2.87e-041803233d54cc767e25d91ed2203d8a03e5bf5e15f21699
ToppCelldroplet-Heart-nan-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN11A GUCY1A1 TRPC3

2.87e-0418032378fdcfb3fdbf36469cae78407cda5bd0996930d8
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HCN1 TRPC3 SCN2A

2.87e-04180323f6a2208960d0df1500c974cc44c3c054cd7475a9
ToppCellCOVID-19-Heart-Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

GUCY1A1 ADCY3 TRPC4

2.91e-0418132333cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCellfacs-Heart-LA-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANO9 GUCY1A1 TRPC4

3.01e-041833238d45dff06a199b1369576657f7f9dc0249c5f841
ToppCellAdult-Mesenchymal-pericyte_cell-D122|Adult / Lineage, Cell type, age group and donor

ADCY3 TRPC3 TRPC4

3.01e-04183323fc31a43a637423cb3bb9aa184a3a889a0b9aaea6
ToppCellfacs-Heart-LA-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANO9 GUCY1A1 TRPC4

3.01e-04183323421265fa15d5a028cb567bb0904e670473ef102b
ToppCelldroplet-Lung-30m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GUCY1A1 SLC1A6 TRPC3

3.06e-041843237128a2be291544d3df3ed6c80f21ddda8437dcba
ToppCelldroplet-Lung-30m-Mesenchymal-myofibroblast-pericyte_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GUCY1A1 SLC1A6 TRPC3

3.06e-04184323d14238f7b0b55a4c8d7040bea854bd221a66ac30
ToppCellCOVID-19-Heart-Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

GUCY1A1 ADCY3 TRPC4

3.06e-0418432321790cdfa3b4036ad413fd44b94e31563116f25f
ToppCelldroplet-Lung-30m-Mesenchymal-myofibroblast|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GUCY1A1 SLC1A6 TRPC3

3.06e-0418432355dde9c4eebac2a33788c1ff1d8fe312d150fad4
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRG1 PTAFR SCN2A

3.06e-041843239690d4290e70f9bda889754ffb30b0af1f7cb94b
ToppCelldroplet-Heart-nan-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN11A GUCY1A1 TRPC3

3.06e-04184323f4344f3c407b2d4d703fe56e43d84dbfe60ba833
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-Myeloid-cDC2|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR18 PTAFR MS4A4E

3.11e-04185323e592c27f711d13bfc6546893acaab4c8600b0be1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GUCY1A1 ADCY3 TRPC4

3.11e-041853237092436b4db90289516ed130ade596e3021cffaf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GUCY1A1 ADCY3 TRPC4

3.11e-0418532351dfe6ac7df8b330343b37e3bee71e5c65267189
ToppCellfacs-Brain_Non-Myeloid-Cerebellum|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HCN1 TRPC3 SCN2A

3.11e-04185323c083a4974590b9ed3ecafedd3e9cdebc5047fe39
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADCY3 TRPC3 TRPC4

3.11e-04185323a7dba7db79275884b2a93d8a16f2e0c739e71370
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HCN1 TRPC3 SCN2A

3.11e-0418532370de48988c1f8e0809afc8092b663aa439d8e528
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GUCY1A1 ADCY3 TRPC4

3.11e-04185323a8c02cec3c414f3a0da9f2d6d28ce563b0030705
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GUCY1A1 ADCY3 TRPC4

3.11e-04185323a8ca7819066d5297ef6966e7f3e2c9f8a7673fdc
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-Granular_Neuron_CB_Gabra6|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HCN1 TRPC3 SCN2A

3.16e-04186323d6c8ce2a32c218dcc63d861cc247152430ed3c8c
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADCY3 TRPC3 TRPC4

3.16e-04186323888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCellCOPD-Stromal-Pericyte|Stromal / Disease state, Lineage and Cell class

ADCY3 TRPC3 TRPC4

3.21e-04187323406ecd1dabb3ed8d871aef159f7bd1e383434953
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADCY3 TRPC3 TRPC4

3.21e-0418732386250acf088ec0c4800a0dfa031b0d4f7e52c342
ToppCellAdult-Mesenchymal-pericyte_cell|Adult / Lineage, Cell type, age group and donor

ADCY3 TRPC3 TRPC4

3.21e-0418732362759efb660179402fb574ce5701c89a2e17bcfe
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HCN1 TRPC3 SCN2A

3.21e-041873237b2cd0c618ed081223343f3bec2244c8723c9a31
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GUCY1A1 ADCY3 TRPC4

3.21e-04187323958402fcc78f4c7a7d13d659d776f3817137975f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GUCY1A1 ADCY3 TRPC4

3.21e-0418732348bfdb3504c3fefe5db3abac4b790c369680ab4e
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADCY3 TRPC3 TRPC4

3.21e-04187323a2bf958ea59c359a265bfa437d59315e1920cdd4
ToppCellnormal-na-Hematopoietic-progenitor_cell|normal / PBMC cell types (v2) per disease, treatment status, and sex

GUCY1A1 SLC10A5 SLC1A6

3.26e-04188323013162466a3334b6967c0cb670c8577d809b1396
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADCY3 TRPC3 TRPC4

3.26e-04188323ee151792c7ac9afe820f1a281c6dab383799f358
ToppCellnormal-na-Hematopoietic-progenitor_cell-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

GUCY1A1 SLC10A5 SLC1A6

3.26e-04188323be25371e6459504b5f0c9ece3a0fe8f80c7824ca
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADCY3 TRPC3 TRPC4

3.26e-04188323ccddc08121caff958a2b6f9e278a018858af6b4d
ToppCellMesenchymal-pericyte_cell|World / Lineage, Cell type, age group and donor

ADCY3 TRPC3 TRPC4

3.31e-04189323d7ed96add29f219183c802895fbff519b627f635
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC1A6 HCN1 SCN2A

3.31e-04189323f57200c93d39c9bce1adba0a6a1c178c028dd86b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GUCY1A1 ADCY3 TRPC4

3.36e-0419032370c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCellCOVID-19-Heart-EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

GUCY1A1 ADCY3 TRPC4

3.36e-04190323a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADCY3 TRPC3 TRPC4

3.36e-041903234eb92aef1ee868f4537483d19014d947b7684612
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADCY3 TRPC3 TRPC4

3.36e-041903237be4341e2909101d756f14031c21e705eb45e69a
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

GUCY1A1 ADCY3 TRPC4

3.41e-0419132378c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADCY3 TRPC3 TRPC4

3.41e-04191323716dfa7fccbd62b5f574792e68a26dc6c45511dc
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GUCY1A1 ADCY3 TRPC4

3.41e-041913237b0d42a877540dbb346a76a62403e0d5d3e07fa6
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADCY3 TRPC3 TRPC4

3.41e-041913231626b23a57429f835fddc052e3c57f63a4e5b8bb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GUCY1A1 ADCY3 TRPC4

3.41e-04191323cd854b9c426924fdc84bf7f411f6dea447143e79
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC1A2 ADCY3 TRPC4

3.46e-041923234022f208eb5db760abd0aac782a25e8ab63efc64
ToppCelldroplet-Lung-1m-Mesenchymal-myofibroblast|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GUCY1A1 HCN1 TRPC3

3.46e-04192323dc4b4e16e6eb212e45fb70695afd1c7e91027407
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADCY3 TRPC3 TRPC4

3.52e-0419332341ea268e7697101fe70d8ef1045f3a43b9311739
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADCY3 TRPC3 TRPC4

3.52e-04193323b2abe939027a69b60d83a28d4d4cc53ba1dee4c5
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADCY3 TRPC3 TRPC4

3.52e-0419332387ce81ff5b27d9c4300826d76ff5a62e9c408d5d
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADCY3 TRPC3 TRPC4

3.52e-04193323d75f334fe3d9f39ef02a5de0f8202f7a761a8fc8
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC1A6 HCN1 SCN2A

3.52e-041933235fb7808dd971c1cc64c2bd4f8f1de646fb2d77f4
ToppCellIPF-Stromal-Pericyte|Stromal / Disease state, Lineage and Cell class

ADCY3 TRPC3 TRPC4

3.57e-041943233892b188f424ffb80f3c75a1b6709a21c1e1601d
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADCY3 TRPC3 TRPC4

3.57e-041943233cffb5c58f6d5bd254f39ee9c41b7e1e4da0ff75
ToppCell3'-Distal_airway-Mesenchymal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADCY3 TRPC3 TRPC4

3.57e-04194323f5e3e675187afb6efa774f2a8d685efcf813de82
ToppCellCOVID-19-lung-Pericytes/_Smooth_Muscle|lung / Disease (COVID-19 only), tissue and cell type

ADCY3 TRPC3 TRPC4

3.57e-041943235e1e0513a54ec4cf0b247ec85c9fbc68dfac1da3
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC1A2 ADCY3 TRPC4

3.62e-04195323d9a5c75d31c6e8bb1e1ab7fd115ac5deb5fb1c8d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC1A2 ADCY3 TRPC4

3.68e-04196323a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCellcellseq-Mesenchymal-Myocytic-Myocytic_1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADCY3 TRPC3 TRPC4

3.68e-04196323c373465e34e2dd581247962d59e0477aae877079
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC1A2 ADCY3 TRPC4

3.68e-041963233e6803587d8566fd08cb8b290be3b6461743d79c
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GUCY1A1 TRPC3 TRPC4

3.68e-0419632312d9028f90c057c6e5cff00301793fa550e86c5a
ToppCellcellseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADCY3 TRPC3 TRPC4

3.68e-041963238b5337ccf74de90e8b89a02ac00671af1de2cfff
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC1A2 ADCY3 TRPC4

3.73e-04197323b349f8e96d61a4c296af64711e11fc44459a9413
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GUCY1A1 ADCY3 TRPC4

3.73e-04197323bc6c530330907a5ec823cc243c8e9c9e340cfb9c
ToppCellParenchymal-NucSeq-Stromal-Pericyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADCY3 TRPC3 TRPC4

3.73e-0419732341dd312f46a2b983c8d864adeb6970c0ca4a8048
Drugsodium

ERVK-6 CHRNA9 SLC6A16 SLC1A2 ADCY3 SLC1A6 HCN1 TRPC3 SCN2A TRPC4 TRPC5 SCN4A

2.52e-099443212CID000000923
Drugsipatrigine

SLC6A16 SLC1A2 SCN2A SCN4A

2.05e-0737324CID000060803
Drug1-oleoyl-2-acetylglycerol

TRPC3 TRPC4 TRPC5

1.13e-0615323ctd:C038237
DrugZonisamide

SCN11A SCN2A SCN4A

1.69e-0617323DB00909
Drugmethylglucamine

TRPC3 TRPC4 TRPC5 SCN4A

1.69e-0662324CID000004049
Drugmu-conotoxin KIIIA, Conus kinoshitai

SCN2A SCN4A

1.91e-062322ctd:C502265
Drugglutamate

CHRNA9 SLC1A2 ADCY3 SLC1A6 HCN1 TRPC3 TRPC4 TRPC5 SCN4A

4.82e-06962329CID000000611
DrugFospropofol

SCN2A SCN4A

1.15e-054322DB06716
DrugPropofol

SCN2A SCN4A

1.15e-054322DB00818
Drugpseudococaine

SCN11A CHRNA9 SLC6A16 SLC1A2 ADCY3 SLC1A6 SCN4A

1.16e-05570327CID000002826
Drug1,2-dichlorohexafluorocyclobutane

CHRNA9 SCN2A SCN4A

1.90e-0537323CID000009643
Drug5-bromotryptophan

SCN2A TRPC5

1.91e-055322CID000096735
DrugAPETx1, Anthopleura elegantissima

SCN2A SCN4A

2.86e-056322ctd:C475726
Drug$l^{1}-borane

TRPC3 TRPC4 TRPC5

3.21e-0544323CID006397184
Druglanthanum

ADCY3 TRPC3 TRPC4 TRPC5

3.85e-05136324CID000023926
Drugbeta-hydroxyaspartic acid

SLC1A2 SLC1A6 STT3B

3.92e-0547323CID000005425
Drugfluorocyclobutane

SCN2A SCN4A

4.00e-057322CID011051569
Drugpotassium

CHRNA9 UBE4B SLC1A2 ADCY3 SLC1A6 HCN1 SCN2A SCN4A

5.84e-051008328CID000000813
Drugchloride

ERVK-6 PTAFR SLC6A16 SLC1A2 ADCY3 SLC1A6 SCN2A SCN4A

6.76e-051029328CID000000312
Drugcalmidazolium chloride

ADCY3 TRPC3 TRPC4 TRPC5

7.24e-05160324CID000002531
DrugNSC59257

ADCY3 CYP19A1 TRPC5

7.38e-0558323CID000001094
DrugAC1L1BDQ

ADCY3 TRPC3 TRPC4 TRPC5

9.80e-05173324CID000001394
DrugMethoxychlor

SLC1A2 SLC1A6 CYP19A1 SCN2A TRPC4 SCN4A

1.02e-04549326ctd:D008731
Drugserotonin

SCN11A CHRNA9 SLC6A16 SLC1A2 ADCY3 SLC1A6

1.07e-04554326CID000005202
DrugNSC7524

CHRNA9 ADCY3 SCN2A SCN4A

1.19e-04182324CID000005657
DrugL-Carnosine

SLC1A2 HCN1 STT3B

1.47e-0473323CID000009369
Druganthglutin

SLC1A2 SLC1A6

1.48e-0413322CID000125748
Drug20(S)-Propanaxidiol

SCN2A SCN4A

1.48e-0413322CID005317623
DrugChlorine

PTAFR ADCY3 SLC1A6 CYP19A1 SCN4A

1.49e-04367325ctd:D002713
DrugAC1L1E5T

PTAFR SLC1A2 ADCY3

1.53e-0474323CID000002653
DrugCaffeic acid [3331-39-5]; Down 200; 22.2uM; HL60; HT_HG-U133A

SCN11A PTAFR TRPC4 SLC5A3

1.65e-041983243053_DN
Drughemicholinium-3

CHRNA9 SLC6A16 SLC1A2

1.79e-0478323CID000003585
DrugDL-Serine

ERVK-6 SLC1A2 SLC1A6 SCN2A

1.81e-04203324CID000000617
Drugnonanol

SCN2A SCN4A

1.99e-0415322CID000008914
Drugapholate

SCN11A CYP19A1

1.99e-0415322CID000005845
Drugbumetanide

ERVK-6 SLC1A2 SLC1A6 SCN2A

2.03e-04209324CID000002471
Drugmalonate

CHRNA9 SLC1A2 SLC1A6 SCN2A

2.03e-04209324CID000000867
Drugtetracaine

CHRNA9 ADCY3 SCN4A

2.55e-0488323CID000005411
DrugS-1360

ERVK-6 SCN2A

2.57e-0417322CID006451047
DrugDB08666

ERVK-6 SCN2A SCN4A

2.73e-0490323CID011840988
DrugScorpion Venoms

SCN2A SCN4A

2.89e-0418322ctd:D012604
Drugadenosine diphosphoribose

TRPC3 TRPC4 TRPC5

2.91e-0492323CID000030243
Drugtetradotoxin

SCN11A CHRNA9 HCN1 SCN2A SCN4A

3.04e-04428325CID000020382
DrugChlorpyrifos

ZNF106 GPR18 CHRNA9 SLC1A2 SLC1A6 CYP19A1 TRPC4

3.09e-04960327ctd:D004390
Drug4-azidobenzoic acid

TRPC3 SCN4A

3.22e-0419322CID003034184
Drugcarbachol

CHRNA9 GUCY1A1 ADCY3 TRPC3 TRPC4 TRPC5

3.45e-04688326CID000002551
DrugU1-1

ERVK-6 SCN2A SCN4A

3.50e-0498323CID006914645
DrugGadolinium

TRPC3 TRPC5

3.95e-0421322ctd:D005682
Drugreproterol

ERVK-6 ADCY3

3.95e-0421322CID000025654
Drug1bkm

ERVK-6 SCN11A

3.95e-0421322CID000444589
Drugmethanethiosulfonate

SLC1A2 HCN1 SCN4A

4.05e-04103323CID004188587
DrugAC1NPPZW

HCN1 SCN2A SCN4A

4.05e-04103323CID005183170
DrugDL-valine

SLC1A2 SLC1A6 STT3B

4.29e-04105323CID000001182
Drug3-iodo-4-hydroxybenzoic acid

PTAFR SCN2A

4.34e-0422322CID000449473
Drugbosentan

TRPC3 TRPC4 TRPC5

4.41e-04106323CID000104865
DrugNAIN

ERVK-6 ADCY3

5.18e-0424322CID000195228
Drug1-chloro-1,2,2-trifluorocyclobutane

SCN2A SCN4A

5.18e-0424322CID000079091
Drug3-Nitrobenzaldoxime

UBE4B SLC1A2 SCN4A

5.45e-04114323CID000219132
Druglamotrigine

CYP19A1 SCN2A

5.63e-0425322ctd:C047781
Druganabasine

CHRNA9 CYP19A1

5.63e-0425322CID000002181
DrugMulticide

SCN2A SCN4A

5.63e-0425322CID000024365
Drug7B-forskolin

ADCY3 HCN1

6.09e-0426322CID000130638
DrugClorocruoro Hem

CHRNA9 TRPC3 TRPC4

6.81e-04123323CID003518809
Drugniflumic acid

SLC1A6 CYP19A1 TRPC4

7.13e-04125323CID000004488
Drug2-aminoethyl diphenylborinate

TRPC3 TRPC4 TRPC5

7.47e-04127323CID000001598
Drug1,2-dioxane

CYP19A1 TRPC5

7.59e-0429322CID000138570
DrugLinuron

SLC1A2 SLC1A6 CYP19A1

7.64e-04128323ctd:D008044
Drugenzacamene

SLC1A2 SLC1A6 CYP19A1

7.82e-04129323ctd:C038939
Drugmyo-inositol

GPR18 PTAFR CHRNA9 ADCY3 TRPC3 TRPC4

8.22e-04811326CID000000892
DrugHis-pro-dkp

SLC6A16 SLC1A2

8.68e-0431322CID000065137
DrugAC1L1KC5

CHRNA9 ADCY3 TRPC3 TRPC4 TRPC5

8.81e-04541325CID000005428
Drugoctylmethoxycinnamate

SLC1A2 SLC1A6 CYP19A1

9.70e-04139323ctd:C118580
Drugdodecanethiol

SCN11A SCN4A

9.83e-0433322CID000008195
Drugdibutyryl cyclic 3',5'-AMP

PTAFR SLC1A2 ADCY3 HCN1 CYP19A1

1.04e-03561325CID000002460
DrugBAPTA

CHRNA9 TRPC3 TRPC4 TRPC5

1.06e-03324324CID000104751
Drugtacrine

CHRNA9 SLC1A2 ADCY3

1.07e-03144323CID000001935
DrugD-myo-inositol-1,4,5-triphosphate

PTAFR ADCY3 TRPC3 TRPC4 TRPC5

1.09e-03568325CID000000806
Drugethyldichloroarsine

SLC1A2 SLC1A6

1.11e-0335322CID000011711
Drug11-R

SLC1A2 CYP19A1

1.11e-0335322CID016058680
Drugsalbutamol

ADCY3 CYP19A1 SCN4A

1.12e-03146323CID000002083
Drugazetidine

SLC1A2 CYP19A1

1.17e-0336322CID000010422
Drugbenzocaine

SCN2A SCN4A

1.24e-0337322CID000002337
DrugN,N-diethylbenzamide

ERVK-6 SCN2A

1.30e-0338322CID000015542
Drug2g6p

ADCY3 TRPC3

1.30e-0338322CID002740174
DrugN-bromoacetamide

CYP19A1 SCN4A

1.30e-0338322CID000004353
Drugprocymidone

SLC1A2 SLC1A6 CYP19A1

1.33e-03155323ctd:C035988
DrugAC1L1EST

TRPC3 STT3B

1.37e-0339322CID000002932
Drugbutylparaben

SLC1A2 SLC1A6 CYP19A1

1.38e-03157323ctd:C038091
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN11A SCN2A SCN4A

1.25e-0710313DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN11A SCN2A SCN4A

1.25e-0710313DOID:0080422 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN11A SCN2A SCN4A

2.30e-0712313DOID:0060170 (implicated_via_orthology)
Diseasenicotine dependence (implicated_via_orthology)

TRPC3 TRPC4 TRPC5

2.30e-0712313DOID:0050742 (implicated_via_orthology)
DiseaseBipolar Disorder

SLC1A2 ADCY3 SLC1A6 TRPC3 SCN2A SLC5A3

9.04e-06477316C0005586
Diseaseneurodegenerative disease (implicated_via_orthology)

SLC1A2 SLC1A6 TRPC4 TRPC5

1.59e-05145314DOID:1289 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

SCN11A SLC1A6 SCN2A SCN4A

2.51e-05163314DOID:1826 (implicated_via_orthology)
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

HCN1 SCN2A

3.83e-059312C3502809
DiseaseManic Disorder

TRPC3 SCN2A SLC5A3

5.72e-0571313C0024713
DiseaseManic

TRPC3 SCN2A SLC5A3

7.57e-0578313C0338831
DiseaseDepression, Bipolar

TRPC3 SCN2A SLC5A3

7.87e-0579313C0005587
DiseaseEpilepsy, Cryptogenic

SLC1A2 HCN1 SCN2A

8.79e-0582313C0086237
DiseaseAwakening Epilepsy

SLC1A2 HCN1 SCN2A

8.79e-0582313C0751111
DiseaseAura

SLC1A2 HCN1 SCN2A

8.79e-0582313C0236018
DiseaseEpilepsy

SLC1A2 HCN1 SCN2A

2.04e-04109313C0014544
Diseaseanxiety disorder (implicated_via_orthology)

HCN1 SCN2A

2.44e-0422312DOID:2030 (implicated_via_orthology)
DiseaseGlobal developmental delay

RNF13 GTF3C3 STT3B

3.67e-04133313C0557874
Diseaseautism spectrum disorder (implicated_via_orthology)

SCN2A TRPC4 TRPC5

5.42e-04152313DOID:0060041 (implicated_via_orthology)
DiseaseHypertensive disease

GUCY1A1 TRPC3 TRPC5

1.03e-03190313C0020538

Protein segments in the cluster

PeptideGeneStartEntry
EELMQMLIQMKLSLV

URB2

1006

Q14146
MLLAALMIVSMVVSL

ERVK-19

76

O71037
MLLAALMIVSMVVSL

ERVK-8

76

Q902F8
MLLAALMIVSMVVSL

ERVK-9

76

Q9UKH3
MMNVALVDLIFIMTL

GPR18

61

Q14330
LLAMTVFQLMVAEIM

CHRNA9

276

Q9UGM1
TVILVLTLLMICLMI

ANO9

331

A1A5B4
SMLIRNVAVMLPVML

OR51F2

161

Q8NH61
MVILLAVVTLMVTLV

OR6C4

196

Q8NGE1
DLIMLIMMVGNLVII

HCN1

146

O60741
YIAMVMMKAILVTLL

CYP19A1

441

P11511
MLLAALMIVSMVVSL

ERVK-25

76

P61570
MLLAALMIVSMVVSL

ERVK-6

76

Q69384
NILNEIVMKLVIMIM

SLC1A2

271

P43004
MAMLATMVVQILRLR

ADGRG1

586

Q9Y653
IMLVQVSHMVKLTLM

ADCY3

766

O60266
LMRMLQMLVLPLIVS

SLC1A6

96

P48664
RILIALMSLSMGIIM

MS4A4E

51

Q96PG1
MLLAALMIVSMVVSL

HERVK_113

76

Q902F9
SSLLLLLPLMLMSMV

CXCL17

6

Q6UXB2
VLLIIFVTMMVHLCM

SLC6A16

621

Q9GZN6
DITIMILICLNMVTM

SCN4A

1356

P35499
MVNLTMADMLFLITL

PTAFR

56

P25105
MLLSIGMLMLSATQV

RNF13

1

O43567
LMIIGALTLMIISIM

SLC5A3

191

P53794
LLTIMENLMLLLMIR

OR8S1

36

Q8NH09
ILMTCTSTLLALIMM

SLC10A5

236

Q5PT55
LLTMLAMLLKVAMNR

GTF3C3

556

Q9Y5Q9
VMVRLMLTLTPVVCM

STT3B

456

Q8TCJ2
LIGQILMEVLMMSTQ

UBE4B

201

O95155
TVFMMVMVIGNLVVL

SCN2A

961

Q99250
IIISLIILNMISMMA

SCN11A

1371

Q9UI33
ISLVVLLNMLIAMMN

TRPC5

611

Q9UL62
LLMLKQQITMEMSAL

ZNF106

1091

Q9H2Y7
SAIMILTMLLMLKLC

SLC66A2

81

Q8N2U9
VISLVVLLNMLIAMM

TRPC4

606

Q9UBN4
MVVVLLNMLIAMINS

TRPC3

646

Q13507
AVQIALMALKMMELS

GUCY1A1

546

Q02108