Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	site of double-strand break	MRE11 RNF169 RFWD3 TONSL HTATSF1 TP53BP1	9.27e-05	101	151	6	GO:0035861
Domain	SPEC	SYNE1 MCF2L2 DST MACF1 MCF2L	4.95e-06	32	148	5	SM00150
Domain	Spectrin/alpha-actinin	SYNE1 MCF2L2 DST MACF1 MCF2L	4.95e-06	32	148	5	IPR018159
Domain	PH_dom-like	PHLDB3 NET1 MCF2L2 ANKS1B BCR SHC3 RGS12 EXOC8 ELMO3 PTPN13 IQSEC1 LRBA MCF2L AGAP2	7.63e-06	426	148	14	IPR011993
Domain	-	PHLDB3 NET1 MCF2L2 ANKS1B BCR SHC3 RGS12 EXOC8 ELMO3 PTPN13 IQSEC1 MCF2L AGAP2	1.45e-05	391	148	13	2.30.29.30
Domain	Spectrin	SYNE1 DST MACF1 MCF2L	2.98e-05	23	148	4	PF00435
Domain	DUF4659	CCDC185 CCDC177	6.24e-05	2	148	2	IPR029090
Domain	DUF4659	CCDC185 CCDC177	6.24e-05	2	148	2	PF15558
Domain	Spectrin_repeat	SYNE1 DST MACF1 MCF2L	7.71e-05	29	148	4	IPR002017
Domain	Laminin_EGF	NTN3 LAMA5 SCARF1 MEGF8	1.64e-04	35	148	4	PF00053
Domain	Laminin_EGF	NTN3 LAMA5 SCARF1 MEGF8	2.27e-04	38	148	4	IPR002049
Domain	Growth_fac_rcpt_	NTN3 LAMA5 GPR179 SCARF1 HMCN2 MEGF8 LTBP2	2.48e-04	156	148	7	IPR009030
Domain	PH	PHLDB3 NET1 MCF2L2 BCR EXOC8 ELMO3 IQSEC1 MCF2L AGAP2	3.81e-04	278	148	9	SM00233
Domain	PH_DOMAIN	PHLDB3 NET1 MCF2L2 BCR EXOC8 ELMO3 IQSEC1 MCF2L AGAP2	3.91e-04	279	148	9	PS50003
Domain	PH_domain	PHLDB3 NET1 MCF2L2 BCR EXOC8 ELMO3 IQSEC1 MCF2L AGAP2	4.01e-04	280	148	9	IPR001849
Domain	ACTININ_2	SYNE1 DST MACF1	7.69e-04	23	148	3	PS00020
Domain	ACTININ_1	SYNE1 DST MACF1	7.69e-04	23	148	3	PS00019
Domain	Actinin_actin-bd_CS	SYNE1 DST MACF1	7.69e-04	23	148	3	IPR001589
Domain	-	DST MACF1	9.16e-04	6	148	2	3.90.1290.10
Domain	GAR	DST MACF1	9.16e-04	6	148	2	PS51460
Domain	GAS2	DST MACF1	9.16e-04	6	148	2	PF02187
Domain	-	DST MACF1	9.16e-04	6	148	2	3.30.920.20
Domain	GAS_dom	DST MACF1	9.16e-04	6	148	2	IPR003108
Domain	GAS2	DST MACF1	9.16e-04	6	148	2	SM00243
Domain	EGF_1	NTN3 NRG2 LAMA5 SCARF1 HEG1 HMCN2 MEGF8 LTBP2	9.86e-04	255	148	8	PS00022
Domain	EGF-like_CS	NTN3 NRG2 LAMA5 SCARF1 HEG1 HMCN2 MEGF8 LTBP2	1.14e-03	261	148	8	IPR013032
Domain	EGF_2	NTN3 NRG2 LAMA5 SCARF1 HEG1 HMCN2 MEGF8 LTBP2	1.26e-03	265	148	8	PS01186
Domain	Plectin	DST MACF1	1.28e-03	7	148	2	PF00681
Domain	Plectin_repeat	DST MACF1	1.28e-03	7	148	2	IPR001101
Domain	PLEC	DST MACF1	1.28e-03	7	148	2	SM00250
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PHLDB3 SETD1A KIF26A SPEG INTS1 LAMA5 BTAF1 SMG5 HES2 BCR ADGRA2 BAHD1 HEG1 DST MEGF8 ZNF516 TMEM132A NAV1 LRBA HERC2 MCF2L SIPA1L2 ZNF839 SPEN TOP3A	2.20e-11	1105	154	25	35748872
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	ANK2 FOXP2 MAP6 SYNE1 APC2 NUMA1 ANKS1B BCR CCDC177 RTN1 CEP170 DST FAM171A2 ZNF516 IQSEC1 NAV1 MACF1 LIMCH1 HERC2 TP53BP1 LRRFIP2 AGAP2	3.30e-10	963	154	22	28671696
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SYNE1 SPEG PHF24 RIMS3 USP31 MEGF8 NAV1 MACF1 LIMCH1 MCF2L SIPA1L2 CROCC SPEN TMEM181	4.32e-09	407	154	14	12693553
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	NET1 BCR RGS12 CEP350 CEP170 USP31 PTPN13 DST FAM171A2 MEGF8 BAIAP2L1 IQSEC1 NAV1 MACF1 LIMCH1 SIPA1L2 SH3RF3 MEX3B CCSER1	1.02e-08	861	154	19	36931259
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	ANK2 PHF24 RIMS3 NRG2 RTN1 DST IQSEC1 MACF1 ATP1A1 SIPA1L2 MAP3K7 AGAP2	5.43e-08	347	154	12	17114649
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	SETD1A ACACB APC2 NUMA1 MRPL43 BAIAP2L1 CYP26C1 TONSL HTATSF1 AFF1 IGSF9B SPEN MEX3B	7.12e-08	430	154	13	35044719
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	FAM53A WDR27 BTAF1 BCR PTPN18 AR CEP170 PTPN13 PKP3 PKD2 AUTS2 NAV1 AFF1 MACF1 IGSF9B LIMCH1 OLFM2 LRBA MCF2L CROCC ZNF839 SH3RF3 TMEM181	1.85e-07	1489	154	23	28611215
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	MRE11 ANK2 ACACB NUMA1 GPATCH4 BTAF1 GPKOW RTN1 CEP170 PTPN13 DST HTATSF1 MACF1 LRBA ATP1A1 SIPA1L2 SF3B2 TP53BP1	1.93e-07	934	154	18	33916271
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	ACACB MRPL43 BTAF1 PTPN18 CEP170 USP31 HECW2 ZNF516 HTATSF1 ATP1A1 HERC2 SPEN	4.21e-07	420	154	12	28065597
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	PHLDB3 ACACB ITGA2 USP31 PTPN13 DST FAM171A2 BAIAP2L1 MACF1 LRBA ATP1A1 SIPA1L2	4.32e-07	421	154	12	36976175
Pubmed	HENA, heterogeneous network-based data set for Alzheimer's disease.	SYNE1 CEP170 DST NAV1 MACF1 HERC2 CCSER1	1.14e-06	120	154	7	31413325
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	ANK2 MAP6 SYNE1 ANKS1B ITGA2 BCR CCDC177 RTN1 CEP170 USP31 DST HECW2 IQSEC1 NAV1 MACF1 LIMCH1 ATP1A1 SIPA1L2 CROCC LRRFIP2 AGAP2	1.51e-06	1431	154	21	37142655
Pubmed	RNF169 limits 53BP1 deposition at DSBs to stimulate single-strand annealing repair.	MRE11 RNF169 TP53BP1	1.69e-06	6	154	3	30104380
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	CNOT11 ANKZF1 BCR GPKOW RFWD3 CEP350 CEP170 FBXW8 PDE8B PKP3 SNX18 IQSEC1 MLLT3 LSM11 LIMCH1 MAP3K7 ANKRD52	3.90e-06	1038	154	17	26673895
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	BCR RTN1 CEP350 PTPN13 DST BAIAP2L1 MACF1 SIPA1L2	4.58e-06	209	154	8	36779422
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SETD1A KIF26A PHRF1 LAMA5 SMG5 BCR ADGRA2 BAHD1 DST HECW2 ZNF516 AUTS2	4.60e-06	529	154	12	14621295
Pubmed	Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	KIF26A SYNE1 USP31 HEG1 NAV1 MACF1	6.86e-06	103	154	6	10574462
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	MRE11 PHRF1 INTS1 NUMA1 CEP170 DST MACF1 ATP1A1 HERC2 SPEN ANKRD52 SF3B2 TP53BP1	7.45e-06	653	154	13	22586326
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	MRE11 RNF169 PDE4C PHRF1 NUMA1 BTAF1 PKP3 ZNF516 IQSEC1 AFF1 LIMCH1 SPEN SF3B2 TP53BP1	9.72e-06	774	154	14	15302935
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	MRE11 RNF169 CNOT11 NET1 ACAD9 SYNE1 PHRF1 INTS1 LAMA5 GPATCH4 ANKZF1 PTPN13 DST MACF1 LSM11 LIMCH1 HERC2 CROCC SPEN TARBP2	1.10e-05	1497	154	20	31527615
Pubmed	A human MAP kinase interactome.	TBX3 WIPF1 KIF26A SYNE1 CEP350 DST NAV1 MACF1 HERC2 ZNF839 MAP3K7	1.19e-05	486	154	11	20936779
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	BCR BAIAP2L1 ZNF516 TONSL NAV1 MACF1 ATP1A1 SIPA1L2 SPEN ANKRD52 TOP3A TP53BP1	1.32e-05	588	154	12	38580884
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	MRE11 SYNE1 INTS1 NUMA1 BTAF1 CEP350 CEP170 FBXW8 DST PKP3 MACF1 USP39 ATP1A1 HERC2 SPEN SF3B2	1.36e-05	1024	154	16	24711643
Pubmed	SF3B2-Mediated RNA Splicing Drives Human Prostate Cancer Progression.	AR SF3B2	1.95e-05	2	154	2	31431456
Pubmed	MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in 11q23 acute myeloid leukemia.	AFF1 MLLT3	1.95e-05	2	154	2	28114278
Pubmed	Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.	DST MACF1	1.95e-05	2	154	2	11002341
Pubmed	Effects of tumor-suppressor lysyl oxidase propeptide on prostate cancer xenograft growth and its direct interactions with DNA repair pathways.	MRE11 LOX	1.95e-05	2	154	2	24882580
Pubmed	Striated muscle preferentially expressed genes alpha and beta are two serine/threonine protein kinases derived from the same gene as the aortic preferentially expressed gene-1.	KLF11 SPEG	1.95e-05	2	154	2	10973969
Pubmed	hVFL3/CCDC61 is a component of mother centriole subdistal appendages required for centrosome cohesion and positioning.	CCDC61 CEP170	1.95e-05	2	154	2	31789463
Pubmed	The nuclear structural protein NuMA is a negative regulator of 53BP1 in DNA double-strand break repair.	NUMA1 TP53BP1	1.95e-05	2	154	2	30812030
Pubmed	Regulation of chromatin architecture by the PWWP domain-containing DNA damage-responsive factor EXPAND1/MUM1.	PWWP3A TP53BP1	1.95e-05	2	154	2	20347427
Pubmed	Genes on chromosomes 4, 9, and 19 involved in 11q23 abnormalities in acute leukemia share sequence homology and/or common motifs.	AFF1 MLLT3	1.95e-05	2	154	2	8506309
Pubmed	Cell type-specific mechanism of Setd1a heterozygosity in schizophrenia pathogenesis.	SETD1A FOXP2	1.95e-05	2	154	2	35245111
Pubmed	Actin-dependent regulation of cilia length by the inverted formin FHDC1.	CEP170 FHDC1	1.95e-05	2	154	2	29742020
Pubmed	MXD3 Promotes Obesity and the Androgen Receptor Signaling Pathway in Gender-Disparity Hepatocarcinogenesis.	MXD3 AR	1.95e-05	2	154	2	34943942
Pubmed	Retinoic acid catabolizing enzyme CYP26C1 is a genetic modifier in SHOX deficiency.	SHOX CYP26C1	1.95e-05	2	154	2	27861128
Pubmed	MLL fusion partners AF4 and AF9 interact at subnuclear foci.	AFF1 MLLT3	1.95e-05	2	154	2	14603337
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	ADCK1 APC2 ANKS1B CCDC177 PTPN13 IQSEC1 MACF1 HERC2 SIPA1L2 AGAP2	2.37e-05	430	154	10	32581705
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	MCF2L2 BAHD1 DST TMEM132A NAV1 MACF1	2.59e-05	130	154	6	12421765
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	RNF169 CNOT11 CCDC61 CEP350 CEP170 DST ZNF516 TONSL NAV1 LRBA MAP3K7 SPEN	3.27e-05	645	154	12	25281560
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	MRE11 ANK2 NUMA1 MRPL43 GPATCH4 ANKZF1 GPKOW SHC3 CEP350 CEP170 LOX IQSEC1 LIMCH1 ATP1A1 HERC2 TARBP2 SF3B2 LRRFIP2	3.91e-05	1371	154	18	36244648
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	ANK2 ACACB MAP6 ADCK1 ANKS1B BCR RTN1 CEP170 FAM171A2 IQSEC1 NAV1 MACF1 SIPA1L2 MAP3K7 TP53BP1 AGAP2	4.90e-05	1139	154	16	36417873
Pubmed	Expression of the mouse Macf2 gene during inner ear development.	DST MACF1	5.83e-05	3	154	2	12399109
Pubmed	Disruption of Ankyrin B and Caveolin-1 Interaction Sites Alters Na+,K+-ATPase Membrane Diffusion.	ANK2 ATP1A1	5.83e-05	3	154	2	28988699
Pubmed	Differential cleavage of lysyl oxidase by the metalloproteinases BMP1 and ADAMTS2/14 regulates collagen binding through a tyrosine sulfate domain.	ADAMTS2 LOX	5.83e-05	3	154	2	31152061
Pubmed	Dynamics of the DYNLL1-MRE11 complex regulate DNA end resection and recruitment of Shieldin to DSBs.	MRE11 TP53BP1	5.83e-05	3	154	2	37696958
Pubmed	HepaCAM inhibits cell proliferation and invasion in prostate cancer by suppressing nuclear translocation of the androgen receptor via its cytoplasmic domain.	AR HEPACAM	5.83e-05	3	154	2	30664187
Pubmed	circ-PKD2 inhibits carcinogenesis via the miR-204-3p/APC2 axis in oral squamous cell carcinoma.	APC2 PKD2	5.83e-05	3	154	2	31206208
Pubmed	Nuclear IGF1R interacts with NuMA and regulates 53BP1‑dependent DNA double‑strand break repair in colorectal cancer.	NUMA1 TP53BP1	5.83e-05	3	154	2	34165167
Pubmed	Ccdc61 controls centrosomal localization of Cep170 and is required for spindle assembly and symmetry.	CCDC61 CEP170	5.83e-05	3	154	2	30354798
Pubmed	MAP3K7-IKK Inflammatory Signaling Modulates AR Protein Degradation and Prostate Cancer Progression.	AR MAP3K7	5.83e-05	3	154	2	34158377
Pubmed	Induction of integrin α2 in a highly bone metastatic human prostate cancer cell line: roles of RANKL and AR under three-dimensional suspension culture.	ITGA2 AR	5.83e-05	3	154	2	25200184
Pubmed	Variants in RBP4 and AR genes modulate age at onset in familial amyloid polyneuropathy (FAP ATTRV30M).	RBP4 AR	5.83e-05	3	154	2	26286643
Pubmed	Foxp1 expression is essential for sex-specific murine neonatal ultrasonic vocalization.	FOXP2 AR	5.83e-05	3	154	2	28204507
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ANK2 SYNE1 APC2 MCF2L2 RBP4 ANKS1B SMG5 CEP350 SNRNP48 PTPN13 DST MACF1 MLLT3 LRBA HERC2 SF3B2 AGAP2	5.92e-05	1285	154	17	35914814
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	ANK2 SYNE1 CEP170 DST MACF1 CCSER1	6.00e-05	151	154	6	17043677
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	SPEG INTS1 HECW2 SIPA1L2 CCDC191 TMEM181	6.46e-05	153	154	6	10718198
Pubmed	PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.	MRE11 SETD1A TP53BP1	6.62e-05	18	154	3	17500065
Pubmed	The protein interaction landscape of the human CMGC kinase group.	RNF169 CNOT11 MRPL43 CEP350 ZNF516 NAV1 AFF1 MLLT3 USP39 ATP1A1 HERC2 SIPA1L2	6.69e-05	695	154	12	23602568
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	SYNE1 SMG5 ADGRA2 TTC7A DST AUTS2 MACF1	6.86e-05	225	154	7	12168954
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	ACACB ACAD9 SPEG NUMA1 RGS12 LIMCH1 USP39 LRBA ATP1A1 SH3RF3	7.96e-05	497	154	10	36774506
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	SETD1A NUMA1 LAMA5 BCR PTPN13 HECW2 HERC2 SPEN	8.24e-05	313	154	8	38270169
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	ACACB SYNE1 NUMA1 DST MACF1 LRBA SF3B2	8.76e-05	234	154	7	36243803
Pubmed	Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.	SYNE1 DST MACF1	9.18e-05	20	154	3	21689717
Pubmed	Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.	MRE11 TBX3 SYNE1 FBXW8 PKP3 ZNF516 SNX18 TARBP2	9.81e-05	321	154	8	32098917
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	MRE11 CNOT11 GPATCH4 SMG5 BCR CEP350 CEP170 PTPN13 SNX18 MACF1 ATP1A1 SPEN	9.83e-05	724	154	12	36232890
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	MAP6 SYNE1 INTS1 CCDC61 CEP170 SNRNP48 PTPN13 DST IQSEC1 MACF1 USP39 SIPA1L2 SPEN PIK3R5 SF3B2	9.86e-05	1082	154	15	38697112
Pubmed	Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.	CNOT11 ACACB INTS1 CEP350 CEP170 LRBA SIPA1L2	1.08e-04	242	154	7	34011540
Pubmed	The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair.	RNF169 TONSL AFF1 MLLT3 LRBA	1.13e-04	106	154	5	31024071
Pubmed	Characterization of cDNA clones in size-fractionated cDNA libraries from human brain.	CEP350 CEP170 MACF1 CROCC	1.14e-04	56	154	4	9455484
Pubmed	Polycystin-2 and phosphodiesterase 4C are components of a ciliary A-kinase anchoring protein complex that is disrupted in cystic kidney diseases.	PDE4C PKD2	1.16e-04	4	154	2	21670265
Pubmed	MRE11 promotes AKT phosphorylation in direct response to DNA double-strand breaks.	MRE11 TP53BP1	1.16e-04	4	154	2	21623170
Pubmed	Importance of a specific amino acid pairing for murine MLL leukemias driven by MLLT1/3 or AFF1/4.	AFF1 MLLT3	1.16e-04	4	154	2	25282333
Pubmed	GFI1 facilitates efficient DNA repair by regulating PRMT1 dependent methylation of MRE11 and 53BP1.	MRE11 TP53BP1	1.16e-04	4	154	2	29651020
Pubmed	Oncogenic All1 fusion proteins target Drosha-mediated microRNA processing.	AFF1 MLLT3	1.16e-04	4	154	2	17581865
Pubmed	Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.	DST MACF1	1.16e-04	4	154	2	8954775
Pubmed	Prognostic impact of KMT2A-AFF1-positivity in 926 BCR-ABL1-negative B-lineage acute lymphoblastic leukemia patients treated in GIMEMA clinical trials since 1996.	BCR AFF1	1.16e-04	4	154	2	34048072
Pubmed	Agonist-antagonist induced coactivator and corepressor interplay on the human androgen receptor.	AR SPEN	1.16e-04	4	154	2	15062576
Pubmed	Multiple Isoforms of Nesprin1 Are Integral Components of Ciliary Rootlets.	SYNE1 CROCC	1.16e-04	4	154	2	28625779
Pubmed	MARK3-mediated phosphorylation of ARHGEF2 couples microtubules to the actin cytoskeleton to establish cell polarity.	CEP170 PTPN13 MACF1 ANKRD52	1.22e-04	57	154	4	29089450
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	MRE11 TBX3 FOXP2 NET1 PHRF1 GPATCH4 BCR TTC7A CEP170 HMCN2 IQSEC1 MACF1 SIPA1L2 ANKRD52 TARBP2	1.38e-04	1116	154	15	31753913
Pubmed	Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families.	ACACB SYNE1 ITGA2 STX12 HEG1 LRBA ATP1A1 CROCC	1.43e-04	339	154	8	37232246
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	MRE11 ACAD9 SARM1 MRPL43 CEP350 CEP170 SNRNP48 PTPN13 LOX LIMCH1 HERC2 LRRFIP2	1.43e-04	754	154	12	33060197
Pubmed	PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.	MRE11 INTS1 NUMA1 RFWD3 PKP3 LIMCH1 SF3B2 TOP3A	1.46e-04	340	154	8	24332808
Pubmed	A protein interaction network for Ecm29 links the 26 S proteasome to molecular motors and endosomal components.	ANK2 SYNE1 DST SF3B2	1.49e-04	60	154	4	20682791
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	BORCS6 RNF169 CEP350 CEP170 NAV1 SPEN	1.78e-04	184	154	6	32908313
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	ACACB CEP170 PTPN13 DST SNX18 NAV1 SIPA1L2 ANKRD52 SH3RF3	1.78e-04	446	154	9	24255178
Pubmed	Interaction network of human early embryonic transcription factors.	SETD1A TBX3 ACACB FOXP2 ZNF516 AUTS2 ATP1A1 SPEN	1.81e-04	351	154	8	38297188
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	ACACB GPATCH4 CEP350 PTPN13 DST FAM171A2 BAIAP2L1 PWWP3A LRBA ATP1A1 MAP3K7 SPEN	1.89e-04	777	154	12	35844135
Pubmed	Functional redundancy between human SHOX and mouse Shox2 genes in the regulation of sinoatrial node formation and pacemaking function.	TBX3 SHOX	1.93e-04	5	154	2	21454626
Pubmed	Ubiquitin Phosphorylation at Thr12 Modulates the DNA Damage Response.	RNF169 TP53BP1	1.93e-04	5	154	2	33022275
Pubmed	Identification, characterization, and localization of a novel kidney polycystin-1-polycystin-2 complex.	PKD2 ATP1A1	1.93e-04	5	154	2	11901144
Pubmed	Ankyrin-B coordinates the Na/K ATPase, Na/Ca exchanger, and InsP3 receptor in a cardiac T-tubule/SR microdomain.	ANK2 ATP1A1	1.93e-04	5	154	2	16292983
Pubmed	Structure and function of hemidesmosomes: more than simple adhesion complexes.	LAMA5 DST	1.93e-04	5	154	2	10201522
Pubmed	Leukemia fusion target AF9 is an intrinsically disordered transcriptional regulator that recruits multiple partners via coupled folding and binding.	AFF1 MLLT3	1.93e-04	5	154	2	23260655
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	CNOT11 SYNE1 NUMA1 MRPL43 GPATCH4 GPKOW CEP350 CEP170 HTATSF1 USP39 HERC2 SF3B2 TOP3A TP53BP1 LRRFIP2	2.00e-04	1155	154	15	20360068
Pubmed	Proteomic characterization of the human centrosome by protein correlation profiling.	CEP350 CEP170 CROCC	2.05e-04	26	154	3	14654843
Pubmed	The DNA sequence and biological annotation of human chromosome 1.	CCDC185 RIMS3 SMG5 HES2 PPCS EXOC8 CEP350 CEP170 MACF1 BCAR3 ATP1A1 SIPA1L2 CROCC SPEN	2.10e-04	1031	154	14	16710414
Pubmed	Human transcription factor protein interaction networks.	MRE11 SETD1A CNOT11 ACACB FOXP2 NUMA1 MRPL43 GPATCH4 SMG5 FIGN DST ZNF516 AUTS2 ATP1A1 HERC2 SPEN TP53BP1	2.11e-04	1429	154	17	35140242
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	MRE11 TBX3 RNF169 PHRF1 INTS1 NUMA1 GPATCH4 RFWD3 DST PKP3 TONSL HTATSF1 USP39 SPEN SF3B2 TOP3A	2.13e-04	1294	154	16	30804502
Interaction	TOP3B interactions	PHLDB3 SETD1A CNOT11 KIF26A SPEG INTS1 LAMA5 BTAF1 SMG5 HES2 BCR ADGRA2 BAHD1 HEG1 DST MEGF8 ZNF516 TMEM132A NAV1 LRBA HERC2 MCF2L SIPA1L2 ZNF839 SPEN MEX3B TOP3A TP53BP1	3.12e-06	1470	149	28	int:TOP3B
Interaction	SAMD4B interactions	CNOT11 SMG5 BCR CEP350 NAV1 SIPA1L2 ANKRD52 MEX3B	3.50e-06	122	149	8	int:SAMD4B
Interaction	YWHAZ interactions	KLF11 MAP6 SPEG RIMS3 BCR AR RGS12 EXOC8 CEP170 USP31 PTPN13 KRT24 DST FAM171A2 BAIAP2L1 NAV1 MACF1 ATP1A1 HERC2 SIPA1L2 ZNF839 MEX3B SF3B2 TP53BP1 CCSER1	1.25e-05	1319	149	25	int:YWHAZ
Interaction	TNIK interactions	ANK2 FOXP2 SYNE1 BCR CEP170 DST IQSEC1 MACF1 HERC2 MAP3K7 TP53BP1 AGAP2	2.72e-05	381	149	12	int:TNIK
GeneFamily	Ankyrin repeat domain containing	ANK2 ANKS1B ANKZF1 ASB18 TONSL ANKRD52 AGAP2	5.59e-04	242	106	7	403
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	NET1 MCF2L2 BCR MCF2L	6.08e-04	66	106	4	722
GeneFamily	EF-hand domain containing\|Plakins	DST MACF1	9.32e-04	8	106	2	939
GeneFamily	AF4/FMR2 family\|Super elongation complex	AFF1 MLLT3	1.19e-03	9	106	2	1280
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder epithelial cells_emap-30875_k-means-cluster#3_top-relative-expression-ranked_1000	TBX3 KLF11 ANK2 FOXP2 CEP350 USP31 AUTS2 MLLT3	1.70e-05	157	151	8	gudmap_developingLowerUrinaryTract_e13.5_bladder epithelial cells_1000_k3
ToppCell	renal_papilla_nuclei-Adult_normal_reference\|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	TBX3 ANK2 ACACB ANKS1B HEG1 PKD2 AUTS2 NAV1 LRBA	2.42e-08	192	154	9	6c106b91e46eabbe686a52a65a9c94ad9cbe9390
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TBX3 ANK2 MAP6 RIMS3 APC2 RTN1 DST OLFM2 SRRM3	3.29e-08	199	154	9	86739a6f5e0fa7448389b97b3c4de41f2a7d7ebd
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TBX3 JPH4 ANK2 MAP6 RIMS3 APC2 RTN1 OLFM2 SRRM3	3.29e-08	199	154	9	ce8dbfd969b3b9c08e1c57c2bfd899818e878731
ToppCell	Sigmoid-(5)_Dendritic_cell-(51)_cDC1\|Sigmoid / shred on region, Cell_type, and subtype	NET1 RGS12 SCARF1 DST PDE8B ZNF516 NAV1 LIMCH1 CCSER1	3.43e-08	200	154	9	4ce0a2238c90622e41fd86ac4b7d82adf4af2c3b
ToppCell	Sigmoid-Dendritic_cell-cDC1\|Sigmoid / Region, Cell class and subclass	NET1 RGS12 SCARF1 DST PDE8B ZNF516 NAV1 LIMCH1 CCSER1	3.43e-08	200	154	9	3523ec986e8c9e176e08836c974b1de8b56d8b16
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal-Cortical_neuron\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	JPH4 ANK2 MAP6 RTN1 CEP170 USP31 AUTS2 MLLT3 LIMCH1	3.43e-08	200	154	9	5b3df61ff421846ef4cabf1bd5355534c8b95509
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TBX3 APC2 ITGA2 RTN1 AR RGS12 SCARF1 PDE8B	1.37e-07	169	154	8	8a6d05b5d60b2b2e43a8ff7521feb79cd6dbd940
ToppCell	facs-Marrow-T_cells-18m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NET1 CHDH NRG2 SMG5 PLA2G4D SNX18 SCT ATP1A1	1.88e-07	176	154	8	74f851a398c7562dd713bc0d8d488c0037243112
ToppCell	facs-Marrow-T_cells-18m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NET1 CHDH NRG2 SMG5 PLA2G4D SNX18 SCT ATP1A1	1.88e-07	176	154	8	31b5459a978d5cdde0af03a77401e0464d8c95ba
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ANK2 ADAMTS2 ITGA2 DST PKD2 MACF1 LTBP2 LIMCH1	3.50e-07	191	154	8	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ANK2 ADAMTS2 ITGA2 DST PKD2 MACF1 LTBP2 LIMCH1	3.64e-07	192	154	8	99ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCell	facs-Aorta-Heart-3m\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NET1 SYNE1 CEP350 HEG1 IQSEC1 MACF1 ATP1A1 HERC2	3.64e-07	192	154	8	1ccc47792edf9ee23501c8e2165d11271636b66a
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TBX3 ANK2 MAP6 KIF26A RIMS3 APC2 RTN1 SRRM3	4.43e-07	197	154	8	fd43fc1cbf0c17b370397d73dddc572565a759c7
ToppCell	5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TBX3 ANK2 MAP6 RIMS3 APC2 RTN1 OLFM2 SRRM3	4.43e-07	197	154	8	a07e1a9b95c9f8a09452cbfe5a9f06648f66e29e
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_B-Branch_B2_(eMN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TBX3 JPH4 ANK2 MAP6 APC2 RTN1 OLFM2 SRRM3	4.60e-07	198	154	8	85881637641d8996be2edc65c4bceff0433135e7
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TBX3 JPH4 ANK2 KIF26A RIMS3 APC2 RTN1 SRRM3	4.60e-07	198	154	8	50504a3871f76d6a5b439a56450d7770f4501eb0
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TBX3 JPH4 ANK2 MAP6 RIMS3 APC2 RTN1 SRRM3	4.60e-07	198	154	8	800ade4261695f2efd869d2b1243571de963c431
ToppCell	Neuron\|World / Primary Cells by Cluster	JPH4 ANK2 MAP6 RTN1 CEP170 AUTS2 MLLT3 LIMCH1	4.78e-07	199	154	8	1f8104fd92f04690b41d9d07ac08dc59d76bb97d
ToppCell	Neuron-Postmitotic\|World / Primary Cells by Cluster	JPH4 ANK2 MAP6 RTN1 CEP170 AUTS2 MLLT3 LIMCH1	4.78e-07	199	154	8	1973527f8a7d4c6490d75c0d0ea153688166a08b
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_\|World / Primary Cells by Cluster	JPH4 ANK2 MAP6 RTN1 CEP170 AUTS2 MLLT3 LIMCH1	4.78e-07	199	154	8	058373b4ac3cec2108cb24265628ff0a50646e33
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Neuronal\|10w / Sample Type, Dataset, Time_group, and Cell type.	JPH4 ANK2 FOXP2 RTN1 CEP170 AUTS2 NAV1 SRRM3	4.96e-07	200	154	8	979258173b82f37aeaaedd53b4a527da1dbe1b80
ToppCell	ICU-SEP-Myeloid-cDC1\|ICU-SEP / Disease, Lineage and Cell Type	NET1 RIMS3 LAMA5 DST HECW2 LIMCH1 CCSER1	1.51e-06	161	154	7	9fb73909fc2ec99f96ca2eed1a053bce89de7d16
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	MCF2L2 INTS1 NRG2 WDR27 CCDC61 AR ZNF839	1.51e-06	161	154	7	2fe77af3b41e6eacb707a64feea18f9991618173
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	FOXP2 SYNE1 LAMA5 PTPN13 LSM11 LIMCH1 CROCC	1.57e-06	162	154	7	2259e9536147e9cdee772e3a30ba7d104573262c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TBX3 JPH4 SYNE1 HEG1 PDE8B HECW2 NAV1	2.08e-06	169	154	7	987ff79ad563825dd9877ea8ccb536758f8c6700
ToppCell	BL-critical-LOC-Epithelial-Ionocyte\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	JPH4 ANK2 FIGN ADGRA2 AR DST LIMCH1	2.16e-06	170	154	7	b465df2dac6b4e98b4ede6ad0c6347656757885c
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANK2 ADAMTS2 SYNE1 GPKOW ZNF516 LTBP2 MAP3K7	2.62e-06	175	154	7	1d8aab491dcc27ea5dbfb6462d18ee280b21a05e
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANK2 ADAMTS2 SYNE1 GPKOW ZNF516 LTBP2 MAP3K7	2.62e-06	175	154	7	427a7ee92fe16a90625946492062d37aa0f7235b
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_A\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	JPH4 KIF26A APC2 ANKS1B RTN1 GPR179 SRRM3	2.72e-06	176	154	7	116741fef5895ca85057d2d31eca9eba5764ab44
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	JPH4 KIF26A APC2 ANKS1B RTN1 GPR179 SRRM3	2.72e-06	176	154	7	5b707f58d164ee7a6a527dd5d053472ce9a631c1
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TBX3 SYNE1 HEG1 HECW2 NAV1 SH3RF3 SPACA3	2.72e-06	176	154	7	dc5a22f9d1347f157bdd93e6e5769b983deccf1a
ToppCell	droplet-Heart-HEART-1m-Mesenchymal-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLF11 NET1 GIPC3 TONSL OLFM2 RELT RAPGEFL1	3.04e-06	179	154	7	dd94ebe69ade6f51b94058abe066216f0de9feda
ToppCell	renal_papilla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	TBX3 MCF2L2 BAIAP2L1 PKD2 AUTS2 NAV1 LRBA	3.16e-06	180	154	7	49829e833fe6d2431cfd2e8f378c2aaa3b2b46a4
ToppCell	Fetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TBX3 LAMA5 USP31 HECW2 NAV1 SIPA1L2 SH3RF3	3.16e-06	180	154	7	d8ef44710a77ad0fc03243428e5e1dc4d41200cb
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	ANK2 ACACB ASB18 DST LIMCH1 LRRFIP2 CCSER1	3.65e-06	184	154	7	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TBX3 ACACB USP31 HEG1 HECW2 BCAR3 MCF2L	4.21e-06	188	154	7	789d1be574e693d7bdd488f3c72c6df788e47b47
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TBX3 JPH4 ANK2 MAP6 APC2 RTN1 SRRM3	4.21e-06	188	154	7	bd091503f580dedab40e0996273101285d24b586
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TBX3 ANK2 KIF26A RIMS3 APC2 RTN1 SRRM3	4.36e-06	189	154	7	cceca3d14dd559bbb2cb4b81ea12c2b62d18ee49
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NET1 ADAMTS2 HEG1 DST NAV1 MACF1 LTBP2	4.51e-06	190	154	7	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	Mesenchymal_cells-Smooth_muscle\|World / Lineage and Cell class	TBX3 PDE4C SPEG STYXL2 BCR PDE8B BCAR3	4.51e-06	190	154	7	5aa62a363a25f4a110136263b21289a11e8c1e6d
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	FOXP2 SHC3 PTPN13 AUTS2 LIMCH1 FHDC1 CCSER1	4.67e-06	191	154	7	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	Control-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	FOXP2 SYNE1 PTPN13 AUTS2 MLLT3 LIMCH1 FHDC1	4.83e-06	192	154	7	1bfd022d5b87cf8a5d5069f559339a553a52a0a2
ToppCell	wk_08-11-Epithelial-PNS-KCNIP4+_neuron\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	JPH4 ANK2 RIMS3 APC2 RTN1 GPR179 SRRM3	4.83e-06	192	154	7	53642c88891f4e4e14b1740c5ced759b7d8b3572
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FOXP2 SYNE1 SHC3 PTPN13 AUTS2 LIMCH1 FHDC1	5.00e-06	193	154	7	fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TBX3 ANK2 KIF26A RIMS3 MCF2L2 RTN1 SRRM3	5.00e-06	193	154	7	a189d46c39067b717509cd144e0225cc93d7731d
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TBX3 ANK2 KIF26A RIMS3 APC2 RTN1 SRRM3	5.00e-06	193	154	7	8851275bcf4ecd6e87a91c8784fc5d76d246ff3b
ToppCell	Fetal_29-31_weeks-Endothelial-capillary_endothelial_cell_(Cap1)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ITGA2 USP31 HECW2 NAV1 MCF2L SIPA1L2 SH3RF3	5.00e-06	193	154	7	ad2df9b77999780860141be6ec366afc0172a331
ToppCell	COVID-19-Endothelial_cells-Inflamed_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	TBX3 SYNE1 LAMA5 HECW2 BCAR3 MCF2L SH3RF3	5.00e-06	193	154	7	979ebefa527f86bebeea5d94e626ee6c1cc7d53b
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FOXP2 SYNE1 SHC3 PTPN13 AUTS2 LIMCH1 FHDC1	5.00e-06	193	154	7	f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	JPH4 ANK2 MAP6 RIMS3 APC2 RTN1 SRRM3	5.17e-06	194	154	7	15224fb3e7ca5bd1fb8c41f8275842f737014095
ToppCell	LPS-IL1RA-Endothelial\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TBX3 HEG1 DST HECW2 NAV1 MCF2L SIPA1L2	5.17e-06	194	154	7	43f92b0533e26633dc94cce554045d641ef8fd76
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HEG1 DST HECW2 MACF1 MCF2L SIPA1L2 CCSER1	5.17e-06	194	154	7	0b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCell	LPS-IL1RA-Endothelial-Endothelial\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TBX3 HEG1 DST HECW2 NAV1 MCF2L SIPA1L2	5.17e-06	194	154	7	1d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FOXP2 SYNE1 SHC3 PTPN13 AUTS2 LIMCH1 FHDC1	5.17e-06	194	154	7	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	E17.5-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TBX3 ANK2 NET1 NRG2 LOX MLLT3 LTBP2	5.35e-06	195	154	7	1daddd801bd4596fffbdb822fc326d5127c96004
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	FOXP2 ANKS1B AUTS2 MLLT3 LIMCH1 LRBA CCSER1	5.53e-06	196	154	7	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	COVID-19-lung-Capillary_Aerocytes\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TBX3 SYNE1 LAMA5 RTN1 HECW2 SIPA1L2 SH3RF3	5.53e-06	196	154	7	49cc0a2b9739abad61dff7292ea0b14d28ff35c4
ToppCell	COVID-19-lung-Capillary_Aerocytes\|lung / Disease (COVID-19 only), tissue and cell type	TBX3 SYNE1 LAMA5 RTN1 HECW2 SIPA1L2 SH3RF3	5.53e-06	196	154	7	4ac4073380d939a73cec7413e9f3f5ef616d2924
ToppCell	Sepsis-ICU-SEP-Myeloid-cDC1\|ICU-SEP / Disease, condition lineage and cell class	NET1 RIMS3 LAMA5 DST HECW2 LIMCH1 CCSER1	5.72e-06	197	154	7	e3174e90ea6136f1aa3a4a185b86458e35d51fd4
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A-Branch_A2_(IPAN/IN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TBX3 JPH4 ANK2 MAP6 APC2 RTN1 SRRM3	5.72e-06	197	154	7	27c044833e471a312a572e0b1c83e4bc8a36e896
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A2_(IPAN/IN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TBX3 JPH4 MAP6 APC2 RTN1 OLFM2 SRRM3	5.72e-06	197	154	7	f7eaac1c321710a55e09ffb047a7db2baf7b7e28
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A1_(iMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TBX3 ANK2 KIF26A RIMS3 APC2 RTN1 OLFM2	5.91e-06	198	154	7	b58138581f1a9073267d64c1211c5b9b4de71d3e
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A1_(iMN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TBX3 ANK2 MAP6 RIMS3 APC2 OLFM2 SRRM3	5.91e-06	198	154	7	dac7b68bb8f1c4d8aa7fdfada61f79956866e874
ToppCell	Transverse-(5)_Dendritic_cell-(51)_cDC1\|Transverse / shred on region, Cell_type, and subtype	NET1 RGS12 SCARF1 DST ZNF516 NAV1 CCSER1	6.11e-06	199	154	7	52dd1c4cd372f8ee515307a9200e357bb2145888
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TBX3 ANK2 KIF26A RIMS3 APC2 RTN1 OLFM2	6.11e-06	199	154	7	b4824d3683a4e3025b8e74a0f1755b331b2a0ba7
ToppCell	Caecum-(5)_Dendritic_cell-(51)_cDC1\|Caecum / shred on region, Cell_type, and subtype	NET1 AR SCARF1 DST ZNF516 NAV1 CCSER1	6.11e-06	199	154	7	2b97fda45241b2ce7be904cf081cabcf3eb5ba1d
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	FOXP2 AUTS2 AFF1 MLLT3 LIMCH1 LRBA CCSER1	6.11e-06	199	154	7	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ANK2 ADAMTS2 FIGN ADGRA2 SHC3 LOX LTBP2	6.11e-06	199	154	7	21335475bbfbad8a6943b8076a6c1c67f3eec5d3
ToppCell	Caecum-Dendritic_cell-cDC1\|Caecum / Region, Cell class and subclass	NET1 AR SCARF1 DST ZNF516 NAV1 CCSER1	6.11e-06	199	154	7	9ab38a0060a883de6fe3da8cdac42e124d7981d9
ToppCell	Transverse-Dendritic_cell-cDC1\|Transverse / Region, Cell class and subclass	NET1 RGS12 SCARF1 DST ZNF516 NAV1 CCSER1	6.11e-06	199	154	7	b68419939d206417158a703f60a374bf8ec5d5a1
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate\|5w / Sample Type, Dataset, Time_group, and Cell type.	SETD1A MAP6 RIMS3 CEP170 MEGF8 AUTS2 NAV1	6.31e-06	200	154	7	c92e4fc0442404481fcac623d691dae6215b852d
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_submucosal-gland-SMG_Serous\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	FOXP2 SARM1 MFSD2B PKP3 FHDC1 ANKRD52 CCSER1	6.31e-06	200	154	7	61bae10c8b12196d9cee766897971b81cb897191
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Cortical_neuron\|10w / Sample Type, Dataset, Time_group, and Cell type.	ANK2 FOXP2 RTN1 CEP170 AUTS2 NAV1 SRRM3	6.31e-06	200	154	7	68c90376e2779434e4ad8dc6dd3b44baa700e2f4
ToppCell	(51)_cDC1\|World / shred on Cell_type and subtype	NET1 RGS12 SCARF1 DST ZNF516 NAV1 CCSER1	7.18e-06	204	154	7	a8cf4180c406674b7541917d1fc6127686ba5f8a
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHLDB3 USP31 SNRNP48 LIMCH1 OLFM2 RAPGEFL1	8.28e-06	137	154	6	e9b88ad86b75454a8292a94879c5b665adc42744
ToppCell	droplet-Fat-SCAT-30m-Myeloid-monocyte\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MXD3 ITGA2 TTC7A TONSL ANKRD52 AGAP2	1.55e-05	153	154	6	2731c3d4ac40ecc22108f8f3f45a069077159125
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP6 CCDC177 USP31 AFF1 LRBA ANKRD52	1.67e-05	155	154	6	441fcb6d05364fc6f4973f0b973f1a80b573ce1f
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage_2\|390C / Donor, Lineage, Cell class and subclass (all cells)	MCF2L2 INTS1 NRG2 WDR27 AR ZNF839	1.67e-05	155	154	6	15bacd06cc2b02b13c85bb71c5b758e5ff613e80
ToppCell	severe_COVID-19-cDC\|severe_COVID-19 / disease group, cell group and cell class (v2)	JPH4 DST NAV1 LIMCH1 BCAR3 CCSER1	1.80e-05	157	154	6	ec1978e07e2214048d015d8bb793c1d9991f6e37
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE4C MFSD2B MEGF8 AFF1 FHDC1 OLFM2	2.22e-05	163	154	6	953a7db7e90a913e81002d2141fbbd5f1fdf2197
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHLDB3 MFSD2B AFF1 LIMCH1 FHDC1 OLFM2	2.22e-05	163	154	6	132aece9c79499b4bb3c2bde68d3d7202e1d8772
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	FOXP2 SYNE1 LAMA5 PTPN13 LSM11 CROCC	2.46e-05	166	154	6	89e2b8453180983533faccb4275867861876d7ee
ToppCell	TCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-2\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	GPATCH4 USP31 PWWP3A LTBP2 LIMCH1 SH3RF3	2.64e-05	168	154	6	c70bf73bb800e4722cedc35bbc17ea3113d1012d
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TBX3 SYNE1 ITGA2 RTN1 RGS12 FAM171A2	2.73e-05	169	154	6	41ad349806b279fbe1374b7e3cc7f146a11adb44
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TBX3 SYNE1 ITGA2 RTN1 RGS12 FAM171A2	2.73e-05	169	154	6	42782c61592742190ab0cba8a94f8bdf9c278f90
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231\|Adult / Lineage, Cell type, age group and donor	SHC3 PTPN13 AUTS2 MLLT3 LIMCH1 CCSER1	2.82e-05	170	154	6	269dee5abca9f6aa079f116f0d8f1d198604d9d4
ToppCell	facs-Heart-LV-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX3 PDE4C ADGRA2 SHC3 FBXW8 PDE8B	3.11e-05	173	154	6	d78397e65e997ddb995111a810f0e2a4f67d0765
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TBX3 SYNE1 HEG1 HECW2 NAV1 SH3RF3	3.11e-05	173	154	6	f193c63cc536d891c9d23043765e320252bb6e65
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_28\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ACACB KIF26A ITGA2 GPR179 HECW2 MCF2L	3.11e-05	173	154	6	66488d01e03264fb193285470901c9c4182fbae8
ToppCell	Leuk-UTI-Myeloid-cDC1\|Leuk-UTI / Disease, Lineage and Cell Type	PHLDB3 NET1 MFSD2B DST NAV1 CCSER1	3.11e-05	173	154	6	226bb8d881f32d65c60f5e4c034c6d465f8e7ba5
ToppCell	facs-Heart-LV-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBX3 PDE4C ADGRA2 SHC3 FBXW8 PDE8B	3.11e-05	173	154	6	3c852ffe22f4a5b632463086b08c669310684e80
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TBX3 DST LOX PKD2 MACF1 LTBP2	3.31e-05	175	154	6	1799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TBX3 ADAMTS2 SYNE1 ADGRA2 PDE8B HECW2	3.31e-05	175	154	6	12f5fd83c7710fc0c77406f765d9cbd133433b8b
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHLDB3 RTN1 BAIAP2L1 MCF2L TP53BP1 RAPGEFL1	3.31e-05	175	154	6	31f0fb2e47e357dbf9c15436b7df85b3c370ded7
ToppCell	NS-moderate-d_0-4-Epithelial-Ionocyte\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MXD3 ANK2 AR DST LTBP2 LIMCH1	3.31e-05	175	154	6	a1e0a15c69211d6db2edeb101476f0f6e08b90c8
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NET1 SPEG ADGRA2 IGSF9B LIMCH1 SH3RF3	3.31e-05	175	154	6	316f2ea930437bf1243b1c0f45e6bd864112c6f2
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NET1 SPEG ADGRA2 IGSF9B LIMCH1 SH3RF3	3.31e-05	175	154	6	a9f08e1e4c2997dcdd3e5d92daac480da19100b8
ToppCell	368C-Lymphocytic-NK_cells-NK_cell_E\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	MCF2L2 ELMO3 PTPN13 DST PWWP3A SPEN	3.53e-05	177	154	6	946803293a7955116c80f403e99e4093e798ca3f
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_1\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	RBP4 GPKOW AR ZNF550 OLFM2 AGAP2	3.53e-05	177	154	6	36b5d29caa9cffbc0284f771a4db71aa72171a89
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	NET1 SYNE1 NUMA1 BCR DST HTATSF1	3.53e-05	177	154	6	e8ab340b20cd41554c3841fe980e078e878af35f
Disease	Malignant neoplasm of breast	MRE11 TBX3 ANK2 NET1 SYNE1 APC2 MCF2L2 AR STX12 AFF1 MACF1 LRBA BCAR3 HERC2 SPEN TP53BP1 AGAP2	2.68e-05	1074	147	17	C0006142
Disease	corneal resistance factor	ADAMTS2 ITGA2 STK35 CEP170 PTPN13 LOX ZNF516 AFF1 HERC2 SLC30A10	9.29e-05	451	147	10	EFO_0010067
Disease	complex cortical dysplasia with other brain malformations (is_implicated_in)	KIF26A APC2	1.47e-04	4	147	2	DOID:0090131 (is_implicated_in)
Disease	Precursor B-cell lymphoblastic leukemia	BCR AUTS2 AFF1	1.51e-04	21	147	3	C1292769
Disease	syntaxin-1a measurement	SARM1 RGS12	2.44e-04	5	147	2	EFO_0020759
Disease	interleukin 17 receptor B measurement	CHDH SARM1	3.65e-04	6	147	2	EFO_0008176
Disease	arteriosclerosis (implicated_via_orthology)	LOX MAP3K7	5.09e-04	7	147	2	DOID:2349 (implicated_via_orthology)
Disease	facial hair thickness measurement	FOXP2 AFF1 MACF1	5.40e-04	32	147	3	EFO_0007823
Disease	Abnormality of the skeletal system	APC2 INTS1	6.77e-04	8	147	2	C4021790
Disease	Burkitt Lymphoma	BCR AUTS2 AFF1	7.67e-04	36	147	3	C0006413
Disease	colon cancer (is_implicated_in)	MRE11 PTPN13 PIK3R5	7.67e-04	36	147	3	DOID:219 (is_implicated_in)
Disease	Ehlers-Danlos syndrome (is_implicated_in)	ADAMTS2 LOX	8.67e-04	9	147	2	DOID:13359 (is_implicated_in)
Disease	longitudinal alcohol consumption measurement	SPATA31C1 IGSF9B	8.67e-04	9	147	2	EFO_0007645
Disease	theophylline measurement	ITGA2 CCSER1	1.08e-03	10	147	2	EFO_0021180
Disease	vesicular integral-membrane protein VIP36 measurement	MXD3 SARM1	1.08e-03	10	147	2	EFO_0022012
Disease	1,7-dimethylurate measurement	FOXP2 ITGA2	1.08e-03	10	147	2	EFO_0021512
Disease	cholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement	ACACB SARM1 RGS12 AFF1 MACF1 TP53BP1	1.41e-03	243	147	6	EFO_0004612, EFO_0020944
Disease	interleukin 17 measurement	ADCK1 ANKS1B TTC7A	1.47e-03	45	147	3	EFO_0008174
Disease	diastolic blood pressure, systolic blood pressure	TBX3 ANK2 SPEG FIGN RGS12 CEP350 NAV1 AFF1 OLFM2 CROCC	2.00e-03	670	147	10	EFO_0006335, EFO_0006336
Disease	abdominal adipose tissue measurement	PDE4C ATP1A1 SLC30A10	2.36e-03	53	147	3	EFO_0803316
Disease	cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement	ACACB SARM1 RGS12 AFF1 MACF1 TP53BP1	2.67e-03	276	147	6	EFO_0004612, EFO_0020943
Disease	gout, hyperuricemia	FAM53A PKD2	2.83e-03	16	147	2	EFO_0004274, EFO_0009104
Disease	Night blindness, congenital stationary	RBP4 GPR179	3.19e-03	17	147	2	C0339535
Disease	cholesteryl esters to total lipids in large HDL percentage	CYP26C1 AFF1 TP53BP1	3.21e-03	59	147	3	EFO_0022248
Disease	Myopia	ANKS1B RTN1 RFWD3 IGSF9B MAP3K7 SH3RF3 MEX3B	3.26e-03	385	147	7	HP_0000545
Disease	triglycerides to total lipids in large HDL percentage	RGS12 AFF1 TP53BP1	3.37e-03	60	147	3	EFO_0022330
Disease	lysophosphatidylcholine 22:6 measurement	STK35 SIPA1L2	3.58e-03	18	147	2	EFO_0010365
Disease	triglycerides in small HDL measurement	CYP26C1 AFF1 TP53BP1	3.70e-03	62	147	3	EFO_0022158
Disease	intraocular pressure measurement	ADAMTS2 ELMO3 LOX ZNF516 LTBP2 HERC2 SLC30A10 TMEM181	4.10e-03	509	147	8	EFO_0004695
Disease	unipolar depression, bipolar disorder, schizophrenia	FOXP2 ADAMTS2	4.42e-03	20	147	2	EFO_0003761, MONDO_0004985, MONDO_0005090
Disease	attention deficit hyperactivity disorder (is_implicated_in)	FOXP2 AR	4.42e-03	20	147	2	DOID:1094 (is_implicated_in)
Disease	central corneal thickness	ADAMTS2 ITGA2 STK35 LOX HERC2 SLC30A10	4.63e-03	309	147	6	EFO_0005213
Disease	schizophrenia (implicated_via_orthology)	SETD1A MAP6 RIMS3	4.79e-03	68	147	3	DOID:5419 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
DSARSFLERLEARGG	PTPN18	6	Q99952
SDSLRGSRSLSDVAR	CCDC185	76	Q8N715
ASSRTAEAIIRSGAR	CEP170	1176	Q5SW79
RGIEAALGTRASASS	ADCK1	446	Q86TW2
SRERSASRGRGAARS	CCDC61	301	Q9Y6R9
ASRGRGAARSSSRES	CCDC61	306	Q9Y6R9
RVSSDARAGEALRGS	BCAR3	381	O75815
AGRAGQRRSASRDSL	ADGRA2	1266	Q96PE1
RGSRDALVSGALEST	BCR	471	P11274
RSRRVSLSDGSDSES	MLLT3	441	P42568
GSDAASIRSRATLSE	ACAD9	186	Q9H845
RSLDSRGETTGSGRA	AGAP2	661	Q99490
TSGRETLRLRSGGAA	GIPC3	216	Q8TF64
IERRLRSSSEGTAGS	CCSER1	456	Q9C0I3
GSTADAADLRGRTAL	ANKRD52	711	Q8NB46
GLRDRASAAEAVRSS	HSD11B1L	211	Q7Z5J1
SAATSRAGVRARRAA	ADAMTS2	76	O95450
GARALASAGSESRDE	CHDH	26	Q8NE62
RSLDARLRAADGSLS	OLFM2	101	O95897
SASRRARAGGSQRTD	RFWD3	156	Q6PCD5
ARAGGSQRTDSARLR	RFWD3	161	Q6PCD5
AGSSRESTRKGSRAS	ACACB	181	O00763
RSRRASGLSTEGATG	NET1	16	Q7Z628
SGSELDGRCSLRRGS	NET1	36	Q7Z628
LEGGRSDSLRSFSSD	ANK2	891	Q01484
IVGTRSTRSGSRNGD	ANKS1B	686	Q7Z6G8
DTGTSDASGGSRRAV	HECW2	581	Q9P2P5
ASTSSREGVRGAARR	PHLDB3	86	Q6NSJ2
RGAGERASLRRKDSS	FHDC1	1116	Q9C0D6
RGNGFDRSAETSSLA	FIGN	361	Q5HY92
ELSGRTTRTDGSSVG	LSM11	296	P83369
RERLRADSLDSSGLS	MXD3	146	Q9BW11
AAGKASGADERDTRR	MAP6	226	Q96JE9
SQASAGRRLSDVRGG	INTS1	1486	Q8N201
RSRGSSEAAGSVETR	GPR179	2096	Q6PRD1
AGRESARGDSSVETR	DNAAF2	481	Q9NVR5
RRAASATLDGGRAGD	HES2	121	Q9Y543
SVCSRAGDRGRDVLS	HERC2	3556	O95714
GSRASSRRGSDASDF	DST	7501	Q03001
RVLTLASARASDSGR	HMCN2	2041	Q8NDA2
GLAARRGRAEDSSSS	CELF2-AS1	81	Q8N7Q2
RGETALSAACGAARR	ASB18	251	Q6ZVZ8
GTDLSRGLTSARAAE	ATP1A1	56	P05023
SSTESDLRLRAGGAA	IQSEC1	326	Q6DN90
RGSLRSEVSSEVGST	JPH4	241	Q96JJ6
RLKGRERASTRSSGG	KCNV1	481	Q6PIU1
TRSTEEERAGASTGR	MCF2L2	1076	Q86YR7
GTREAESRACSDGRS	GPATCH4	361	Q5T3I0
ATRAEGQDVASRSRS	FBXW8	71	Q8N3Y1
VGEGAEACSRLSRSR	PDE4C	6	Q08493
RVRRARTELGSGSSA	PDE8B	66	O95263
STLSSQLDAGSRDGR	FOXP2	21	O15409
ARAARDSLSLSSGSG	NRG2	756	O14511
SESGRLSLGASRGSS	MAP3K7	361	O43318
GRTRALSLASSSGSD	AUTS2	41	Q8WXX7
STSRKGDAACSRRGR	MEGF8	921	Q7Z7M0
RDRSSRSASPSVGEE	PHRF1	1026	Q9P1Y6
RASSSRAGGSSSARV	KRT24	6	Q2M2I5
RAGSRASSRRGSDAS	MACF1	3446	O94854
STSSARRRDSGIGEE	LRBA	1596	P50851
TSARRRLADSGDGAG	GPKOW	26	Q92917
ARSTSRAGCGEDARR	KIF26A	586	Q9ULI4
SSGGESSCEEGRARR	KIF26A	736	Q9ULI4
SAKRGREDSRAGRLS	MFSD2B	26	A6NFX1
AVSEGSSSGRAREAS	AR	201	P10275
TLLAETADARGRSGS	HEG1	161	Q9ULI3
SVSGRVSVREEGRSA	LAMA5	941	O15230
SDSGASRLRRQLESG	EXOC8	6	Q8IYI6
TLDADGFSSRVTSRG	ITGA2	701	P17301
DRASRGRRESVVSAA	LRRFIP2	251	Q9Y608
GSRASSRRGSDASDF	MACF1	7321	Q9UPN3
DRGRNVVSASRDGTA	PAAF1	186	Q9BRP4
ALRRLSGALDSGDSR	KCNJ14	6	Q9UNX9
GRSRGDSSRSSASEL	FAM171A2	771	A8MVW0
GLRRSDSVSASERAG	HTATSF1	381	O43719
DSVSASERAGPSRAR	HTATSF1	386	O43719
FRSGEERARRGSSAL	NTN3	491	O00634
SSGRRGATSAEAFLA	PPCS	61	Q9HAB8
SGSESSDRSGFRRQL	APC2	1981	O95996
SGSERTADASNGSLR	CROCC	471	Q5TZA2
GAAADRRADSARTTS	BAIAP2L1	446	Q9UHR4
AGSRAGRSFSSRLQD	BORCS6	151	Q96GS4
ASRDARSSSREQEAG	BTAF1	1471	O14981
ARAPRTSCSGSGERE	ANKZF1	41	Q9H8Y5
TEGRSDSRNSLSGLR	CCDC191	631	Q8NCU4
ASSDRGGRERTAKSG	CEP350	451	Q5VT06
DTSSLAGTRRSRAGD	BAHD1	136	Q8TBE0
ERFGAAREDSRGASS	CYP26C1	431	Q6V0L0
SSGAGLSADRRRSLC	ELMO3	326	Q96BJ8
LRRSSAAGEGTLARA	LTBP2	246	Q14767
DNRTAAARTRTAGSS	LOX	96	P28300
RRGSENSSSEGGALR	MCF2L	586	O15068
SSAVVARALSGGAER	KLF11	141	O14901
GRSRSASRTLRTAGV	HEPACAM	386	Q14CZ8
LSRRREGALSSESGA	CCDC177	236	Q9NQR7
GSTSAAGIEARSRAL	SPACA3	46	Q8IXA5
GTFTSELSRLREGAR	SCT	31	P09683
TARTALSGLSGADGR	IL17RC	66	Q8NAC3
VLRGSSDGRGSDSES	LIMCH1	221	Q9UPQ0
SGGLREGSLSSQDSR	PTPN13	1236	Q12923
RSSARRSQAGVSSGA	NUMA1	1881	Q14980
ETELSGRLRSSRSNG	PLA2G4D	216	Q86XP0
SSSGLRRKGSRDCSV	MEX3B	506	Q6ZN04
NTGLQRSSSDAGRDR	NAV1	571	Q8NEY1
QESSAGTGRADRSLR	PWWP3A	106	Q2TAK8
LGARAREAASREAGS	RTN1	51	Q16799
FSVSRDGASSRGARE	MRPL43	31	Q8N983
RSLSRARSSSDSGSG	SRRM3	421	A6NNA2
TISSSTRGLGAEERR	TBX3	441	O15119
SEGSESSGRSCRNER	SMG5	626	Q9UPR3
GSTRGKRESESRGSS	USP39	11	Q53GS9
RSERSGRDTPASVDS	SYNE1	8266	Q8NF91
SSSSTLARKEAGGRR	TMEM132A	946	Q24JP5
RSRVTRQGSRESTDG	RIMS3	96	Q9UJD0
SAARERAGARLSGSC	SHC3	86	Q92529
RRGSSFGSSRSSVLD	SIPA1L2	1496	Q9P2F8
SGLARSRELGTSDSS	SHOX	41	O15266
SSAAAAAALSRRGRR	RNF169	11	Q8NCN4
RSLGAQSSRAGETRE	SPATA31C1	791	P0DKV0
QRGRADTGLETSTRS	MRE11	591	P49959
ERARAAFLARGSGST	PHF24	296	Q9UPV7
GSGAATETAESRRRS	SETD1A	206	O15047
SSSDGEGALRRRSLR	SETD1A	1381	O15047
AVRGLGAGTESSRRA	SCARF1	776	Q14162
ASARAGSRTSLQGER	AFF1	611	P51825
GDSARSIVAASRAAG	LINC00612	71	Q8N6U2
VASVGSGTDRRDTAA	CLEC20A	311	Q6ZU45
AAEQRGSREAAGSAS	CNOT11	16	Q9UKZ1
ERQASSSSSRAGGLD	PKP3	216	Q9Y446
GSDSAVTLRGTSVER	SLC30A10	186	Q6XR72
SDGDRAARARCGSLS	ZNF516	546	Q92618
SSGDREKDSTRSRGS	SF3B2	346	Q13435
SAAAAEGSATRRARA	STK35	46	Q8TDR2
EGSATRRARAATSRA	STK35	51	Q8TDR2
SSEGSGSRRRDSDRR	ZSCAN10	451	Q96SZ4
RRESQGSVSSAGSLD	RGS12	931	O14924
SIASRSREVSGFRGG	SPEN	96	Q96T58
RSSRQISEDSERTGG	SPEN	1246	Q96T58
SRLQRSGSSEDSGGA	SPEG	2466	Q15772
LRRDSRSLEGSSDTA	PIK3R5	436	Q8WYR1
IRFLQGRSSRDSSAG	SARM1	696	Q6SZW1
GSLTVTSVSREDRGA	IGSF9B	191	Q9UPX0
VSSSSRARGGALSAL	TMEM181	26	Q9P2C4
AGSTAGSLRELATSR	SH3RF3	171	Q8TEJ3
SIARARAGSRLSAEE	STX12	131	Q86Y82
STSGSDSEESRPRAR	TONSL	861	Q96HA7
AALGSGRAERDCRVS	RBP4	11	P02753
STRSDLSLGSRGGSV	SNX18	196	Q96RF0
SDAGSSVGRRRRTLS	STYXL2	421	Q5VZP5
LRSTANRDNDSGGSR	WIPF1	111	O43516
STRRTDVGAGALRRS	TP53BP1	1446	Q12888
DDEDSGHSSRRRGSI	PKD2	816	Q13563
TGDRGRTLESEARSK	TOP3A	951	Q13472
RRGSIGAALSSRDVS	ZNF839	571	A8K0R7
RRARRGVEVAAGASS	RELT	126	Q969Z4
STSSDSRLGRARDEE	ZNF550	116	Q7Z398
DSGSRRASSIAASRL	TTC7A	671	Q9ULT0
ATTREAARGEAARRA	TARBP2	341	Q15633
REGSRQSLGSDRASA	USP31	1156	Q70CQ4
SEGKGSSRSRSSCAR	WDR27	476	A2RRH5
RLAGGATRDSAASDI	RAPGEFL1	161	Q9UHV5
EERRSASVDSRQSGG	SNRNP48	271	Q6IEG0
RESVTSDGSRRSSGD	FAM53A	356	Q6NSI3