Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransporter activity

SLC38A1 SLC6A4 GABRG1 SLC2A10 GPR89B MFSD2A ABCA1 ABCA2 ABCA4 KCNA10 SLC16A2 SLC38A4 NPC1L1 ATP2C2 GPR89A ABCB6 SLC15A5 TTYH3 SLC7A11 ABCA7 SLC35B1 ITPR2 SLC52A3

1.69e-1112896823GO:0005215
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC38A1 SLC6A4 GABRG1 SLC2A10 GPR89B MFSD2A ABCA1 ABCA2 ABCA4 KCNA10 SLC16A2 SLC38A4 ATP2C2 GPR89A ABCB6 SLC15A5 TTYH3 SLC7A11 ABCA7 SLC35B1 ITPR2 SLC52A3

2.28e-1111806822GO:0022857
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC38A1 SLC6A4 SLC2A10 MFSD2A ABCA1 ABCA2 ABCA4 SLC16A2 SLC38A4 ATP2C2 ABCB6 SLC15A5 SLC7A11 ABCA7 SLC35B1

5.26e-114776815GO:0022804
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

MFSD2A ABCA1 ABCA2 ABCA4 ABCA7

3.65e-0828685GO:0140326
GeneOntologyMolecularFunctionABC-type transporter activity

ABCA1 ABCA2 ABCA4 ABCB6 ABCA7

6.70e-0749685GO:0140359
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC38A1 SLC6A4 SLC2A10 MFSD2A SLC16A2 SLC38A4 SLC15A5 SLC7A11 SLC35B1

7.01e-07296689GO:0015291
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

MFSD2A ABCA1 ABCA2 ABCA4 ABCA7

8.21e-0751685GO:0140303
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCA1 ABCA2 ABCA4 ATP2C2 ABCB6 ABCA7

1.91e-06109686GO:0042626
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC38A1 SLC2A10 MFSD2A SLC16A2 SLC38A4 SLC7A11 SLC35B1 SLC52A3

6.73e-06293688GO:0008514
GeneOntologyMolecularFunctionapolipoprotein A-I receptor activity

ABCA1 ABCA7

1.14e-052682GO:0034188
GeneOntologyMolecularFunctionsymporter activity

SLC38A1 SLC6A4 SLC2A10 MFSD2A SLC38A4 SLC15A5

1.21e-05150686GO:0015293
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC38A1 SLC6A4 GABRG1 SLC2A10 GPR89B MFSD2A KCNA10 SLC38A4 ATP2C2 GPR89A TTYH3 ITPR2

1.33e-057936812GO:0015075
GeneOntologyMolecularFunctionfloppase activity

ABCA1 ABCA2 ABCA7

2.05e-0516683GO:0140328
GeneOntologyMolecularFunctionprimary active transmembrane transporter activity

ABCA1 ABCA2 ABCA4 ATP2C2 ABCB6 ABCA7

3.19e-05178686GO:0015399
GeneOntologyMolecularFunctionhistone H3K9 acetyltransferase activity

KAT2B KAT2A

3.42e-053682GO:0043992
GeneOntologyMolecularFunctionapolipoprotein receptor activity

ABCA1 ABCA7

3.42e-053682GO:0030226
GeneOntologyMolecularFunctionG protein-coupled receptor activity

LHCGR ADRA1D OR10J5 OR5G3 CYSLTR1 GPR75 FSHR MRGPRX2 GPRC5D PTGDR GRM8 OR7A2P

3.89e-058846812GO:0004930
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

GABRG1 LHCGR ADRA1D ABCA1 OR10J5 OR5G3 CYSLTR1 GPR75 FSHR MRGPRX2 GPRC5D PTGDR GRM8 ABCA7 OR7A2P

3.94e-0513536815GO:0004888
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC38A1 SLC6A4 SLC2A10 MFSD2A SLC38A4

5.34e-05119685GO:0015294
GeneOntologyMolecularFunctionlipid transporter activity

MFSD2A ABCA1 ABCA2 ABCA4 NPC1L1 ABCA7

5.47e-05196686GO:0005319
GeneOntologyMolecularFunctionalanine:sodium symporter activity

SLC38A1 SLC38A4

6.83e-054682GO:0015655
GeneOntologyMolecularFunctionsphingolipid floppase activity

ABCA1 ABCA2

6.83e-054682GO:0046623
GeneOntologyMolecularFunctionphospholipid transporter activity

MFSD2A ABCA1 ABCA4 ABCA7

1.18e-0474684GO:0005548
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

SLC6A4 GABRG1 GPR89B GPR89A TTYH3

1.64e-04151685GO:0008509
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC38A1 SLC6A4 MFSD2A SLC38A4

1.68e-0481684GO:0015370
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC38A1 SLC6A4 GABRG1 SLC2A10 MFSD2A KCNA10 SLC38A4 ATP2C2 TTYH3 ITPR2

2.32e-047586810GO:0015318
GeneOntologyMolecularFunctionvitamin transmembrane transporter activity

SLC2A10 ABCA4 SLC52A3

2.49e-0436683GO:0090482
GeneOntologyMolecularFunctionphosphatidylcholine floppase activity

ABCA1 ABCA7

3.16e-048682GO:0090554
GeneOntologyMolecularFunctionneutral L-amino acid:sodium symporter activity

SLC38A1 SLC38A4

3.16e-048682GO:0005295
GeneOntologyMolecularFunctionphosphatidylserine floppase activity

ABCA1 ABCA7

4.05e-049682GO:0090556
GeneOntologyMolecularFunctionmonoatomic anion channel activity

GABRG1 GPR89B GPR89A TTYH3

4.22e-04103684GO:0005253
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

SLC38A1 SLC16A2 SLC38A4 SLC7A11

4.54e-04105684GO:0015171
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC38A1 SLC6A4 SLC2A10 MFSD2A SLC38A4 ATP2C2

5.58e-04301686GO:0022853
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC38A1 MFSD2A SLC16A2 SLC38A4 SLC7A11

7.00e-04207685GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC38A1 MFSD2A SLC16A2 SLC38A4 SLC7A11

7.15e-04208685GO:0005342
GeneOntologyMolecularFunctionmonoatomic ion channel activity

SLC6A4 GABRG1 GPR89B KCNA10 GPR89A TTYH3 ITPR2

9.38e-04459687GO:0005216
GeneOntologyMolecularFunctiongated channel activity

GABRG1 GPR89B KCNA10 GPR89A TTYH3 ITPR2

9.59e-04334686GO:0022836
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC38A1 SLC6A4 MFSD2A KCNA10 SLC38A4 ATP2C2 ITPR2

1.01e-03465687GO:0046873
GeneOntologyMolecularFunctionglycerophospholipid flippase activity

MFSD2A ABCA4

1.01e-0314682GO:0140333
GeneOntologyMolecularFunctionG protein-coupled peptide receptor activity

LHCGR CYSLTR1 FSHR MRGPRX2

1.10e-03133684GO:0008528
GeneOntologyMolecularFunctionATP-dependent activity

MFSD2A ABCA1 ABCA2 ABCA4 ATP2C2 ABCB6 MYO15A ABCA7

1.11e-03614688GO:0140657
GeneOntologyMolecularFunctionhistone H3 acetyltransferase activity

KAT2B KAT2A

1.17e-0315682GO:0010484
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC38A1 SLC6A4 SLC2A10 MFSD2A KCNA10 SLC38A4 ATP2C2 ITPR2

1.27e-03627688GO:0022890
GeneOntologyMolecularFunctionalanine transmembrane transporter activity

SLC38A1 SLC38A4

1.33e-0316682GO:0022858
GeneOntologyMolecularFunctionicosanoid receptor activity

CYSLTR1 PTGDR

1.33e-0316682GO:0004953
GeneOntologyMolecularFunctionpeptide receptor activity

LHCGR CYSLTR1 FSHR MRGPRX2

1.33e-03140684GO:0001653
GeneOntologyMolecularFunctionvoltage-gated monoatomic anion channel activity

GPR89B GPR89A

1.50e-0317682GO:0008308
GeneOntologyMolecularFunctionflippase activity

MFSD2A ABCA4

1.50e-0317682GO:0140327
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC38A1 SLC6A4 SLC2A10 MFSD2A KCNA10 SLC38A4 ATP2C2 ITPR2

1.83e-03664688GO:0008324
GeneOntologyMolecularFunctionL-amino acid transmembrane transporter activity

SLC38A1 SLC38A4 SLC7A11

1.83e-0371683GO:0015179
GeneOntologyMolecularFunctionchannel activity

SLC6A4 GABRG1 GPR89B KCNA10 GPR89A TTYH3 ITPR2

2.02e-03525687GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

SLC6A4 GABRG1 GPR89B KCNA10 GPR89A TTYH3 ITPR2

2.05e-03526687GO:0022803
GeneOntologyMolecularFunctionphosphatidylcholine transporter activity

ABCA1 ABCA7

2.09e-0320682GO:0008525
GeneOntologyMolecularFunctionsphingolipid transporter activity

ABCA1 ABCA2

2.09e-0320682GO:0046624
GeneOntologyMolecularFunctionprotein-hormone receptor activity

LHCGR FSHR

2.53e-0322682GO:0016500
GeneOntologyMolecularFunctionamino acid:sodium symporter activity

SLC38A1 SLC38A4

2.76e-0323682GO:0005283
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC38A1 SLC6A4 MFSD2A SLC38A4

2.76e-03171684GO:0015081
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCA1 ABCA2 ABCA4 ATP2C2 ABCB6 ABCA7

3.87e-03441686GO:0016887
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

GABRG1 KCNA10 TTYH3 ITPR2

4.25e-03193684GO:0015276
GeneOntologyMolecularFunctionamino acid:monoatomic cation symporter activity

SLC38A1 SLC38A4

4.37e-0329682GO:0005416
GeneOntologyMolecularFunctionligand-gated channel activity

GABRG1 KCNA10 TTYH3 ITPR2

4.58e-03197684GO:0022834
GeneOntologyMolecularFunctionalcohol binding

ABCA1 NPC1L1 ITPR2

5.10e-03102683GO:0043178
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

KCNA10 ITPR2

5.64e-0333682GO:0005217
GeneOntologyMolecularFunctionlipid binding

ABCA1 MAL ABCA4 RASA4 NPC1L1 RASA4B BSCL2 HSD11B2 ITPR2

6.13e-03988689GO:0008289
GeneOntologyMolecularFunctionorganic acid:sodium symporter activity

SLC38A1 SLC38A4

6.32e-0335682GO:0005343
GeneOntologyMolecularFunctionorganophosphate ester transmembrane transporter activity

MFSD2A SLC35B1

7.81e-0339682GO:0015605
GeneOntologyMolecularFunctionneutral L-amino acid transmembrane transporter activity

SLC38A1 SLC38A4

8.60e-0341682GO:0015175
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

SLC6A4 GABRG1 TTYH3

8.93e-03125683GO:0015108
GeneOntologyBiologicalProcesscirculatory system process

SLC38A1 SLC6A4 SLC2A10 MFSD2A KAT2B ADRA1D ABCA2 SLC16A2 CYSLTR1 ASB3 FSHR HMGCR HSD11B2 CDC42

9.42e-087336814GO:0003013
GeneOntologyBiologicalProcessvascular process in circulatory system

SLC38A1 SLC6A4 SLC2A10 MFSD2A KAT2B ADRA1D ABCA2 SLC16A2 CYSLTR1 HMGCR

1.80e-073446810GO:0003018
GeneOntologyBiologicalProcessorganic hydroxy compound metabolic process

TPO LHCGR ABCA1 ABCA2 LIPA SLC16A2 NPC1L1 POU1F1 HMGCR HSD11B2 SLC7A11 ALG6

1.09e-066416812GO:1901615
GeneOntologyBiologicalProcesslipid translocation

MFSD2A ABCA1 ABCA2 ABCA4 ABCA7

1.59e-0660685GO:0034204
GeneOntologyBiologicalProcessregulation of membrane lipid distribution

MFSD2A ABCA1 ABCA2 ABCA4 ABCA7

2.38e-0665685GO:0097035
GeneOntologyBiologicalProcessorganic anion transport

SLC38A1 LHCGR SLC2A10 MFSD2A SLC16A2 SLC38A4 TTYH3 SLC7A11 SLC35B1 SLC52A3

6.85e-065156810GO:0015711
GeneOntologyBiologicalProcessalcohol metabolic process

LHCGR ABCA1 ABCA2 LIPA NPC1L1 POU1F1 HMGCR HSD11B2 ALG6

8.07e-06412689GO:0006066
GeneOntologyBiologicalProcesstransport across blood-brain barrier

SLC38A1 SLC2A10 MFSD2A ABCA2 SLC16A2

1.01e-0587685GO:0150104
GeneOntologyBiologicalProcesschemical homeostasis

LHCGR GPR89B ABCA1 ABCA2 THADA LIPA OR10J5 NPC1L1 ATP2C2 FSHR GPR89A ABCB6 HMGCR SLC7A11 ITPR2

1.05e-0512496815GO:0048878
GeneOntologyBiologicalProcessvascular transport

SLC38A1 SLC2A10 MFSD2A ABCA2 SLC16A2

1.06e-0588685GO:0010232
GeneOntologyBiologicalProcessalcohol biosynthetic process

LHCGR ABCA2 LIPA NPC1L1 POU1F1 HMGCR

1.17e-05154686GO:0046165
GeneOntologyBiologicalProcessphospholipid translocation

MFSD2A ABCA1 ABCA4 ABCA7

3.25e-0555684GO:0045332
GeneOntologyBiologicalProcessorganic hydroxy compound biosynthetic process

LHCGR ABCA2 LIPA NPC1L1 POU1F1 HMGCR SLC7A11

3.52e-05277687GO:1901617
GeneOntologyBiologicalProcessamino acid import across plasma membrane

SLC38A1 SLC16A2 SLC38A4 SLC7A11

4.01e-0558684GO:0089718
GeneOntologyBiologicalProcessamino acid transport

SLC38A1 SLC6A4 SLC16A2 SLC38A4 TTYH3 SLC7A11

4.45e-05195686GO:0006865
GeneOntologyBiologicalProcessamino acid transmembrane transport

SLC38A1 SLC16A2 SLC38A4 TTYH3 SLC7A11

4.77e-05120685GO:0003333
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SLC38A1 SLC6A4 GABRG1 LHCGR SLC2A10 GPR89B KCNA10 SLC38A4 ATP2C2 GPR89A ABCB6 TTYH3 ITPR2

6.13e-0511156813GO:0034220
GeneOntologyBiologicalProcesscholesterol biosynthetic process

ABCA2 LIPA NPC1L1 HMGCR

6.29e-0565684GO:0006695
GeneOntologyBiologicalProcesssecondary alcohol biosynthetic process

ABCA2 LIPA NPC1L1 HMGCR

6.29e-0565684GO:1902653
GeneOntologyBiologicalProcesslipid homeostasis

ABCA1 ABCA2 THADA LIPA OR10J5 NPC1L1

6.89e-05211686GO:0055088
GeneOntologyBiologicalProcesscognition

SLC6A4 LHCGR MFSD2A KAT2B HMGCR KAT2A SLC7A11 ABCA7

7.38e-05423688GO:0050890
GeneOntologyBiologicalProcesscellular homeostasis

LHCGR SLC2A10 GPR89B ABCA2 THADA ATP2C2 FSHR GPR89A ABCB6 HMGCR SLC7A11 ITPR2

7.77e-059816812GO:0019725
GeneOntologyBiologicalProcesscholesterol transport

ABCA1 ABCA2 LIPA NPC1L1 ABCA7

8.06e-05134685GO:0030301
GeneOntologyBiologicalProcesssterol biosynthetic process

ABCA2 LIPA NPC1L1 HMGCR

9.39e-0572684GO:0016126
GeneOntologyBiologicalProcesslipid localization

LHCGR MFSD2A ABCA1 ABCA2 LIPA ABCA4 NPC1L1 BSCL2 ABCA7

9.53e-05565689GO:0010876
GeneOntologyBiologicalProcesssterol transport

ABCA1 ABCA2 LIPA NPC1L1 ABCA7

9.59e-05139685GO:0015918
GeneOntologyBiologicalProcesssphingolipid translocation

ABCA1 ABCA2

1.06e-045682GO:0099039
GeneOntologyBiologicalProcessintracellular chemical homeostasis

LHCGR GPR89B ABCA2 THADA ATP2C2 FSHR GPR89A ABCB6 HMGCR SLC7A11 ITPR2

1.15e-048666811GO:0055082
GeneOntologyBiologicalProcessplasma lipoprotein particle assembly

MFSD2A ABCA1 ABCA7

1.18e-0429683GO:0034377
GeneOntologyBiologicalProcesscholesterol efflux

ABCA1 ABCA2 LIPA ABCA7

1.22e-0477684GO:0033344
GeneOntologyBiologicalProcessmonoatomic ion transport

SLC38A1 SLC6A4 GABRG1 LHCGR SLC2A10 GPR89B KCNA10 CYSLTR1 SLC38A4 ATP2C2 GPR89A ABCB6 TTYH3 ITPR2

1.30e-0413746814GO:0006811
GeneOntologyBiologicalProcessbehavior

SLC6A4 MFSD2A KAT2B ABCA2 FSHR MRGPRX2 HMGCR KAT2A MYO15A SLC7A11 ABCA7

1.48e-048916811GO:0007610
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

LHCGR ADRA1D ABCA1 OR10J5 OR5G3 CYSLTR1 GPR75 FSHR MRGPRX2 GPRC5D PTGDR CDC42 GRM8 OR7A2P

1.53e-0413956814GO:0007186
GeneOntologyBiologicalProcessprotein-lipid complex assembly

MFSD2A ABCA1 ABCA7

1.74e-0433683GO:0065005
GeneOntologyBiologicalProcessorganic hydroxy compound transport

SLC6A4 ABCA1 ABCA2 LIPA ABCA4 NPC1L1 ABCA7

1.75e-04358687GO:0015850
GeneOntologyBiologicalProcessimport into cell

SLC38A1 SLC6A4 SLC2A10 ABCA1 ABCA2 LIPA SLC16A2 SLC38A4 MYO15A CDC42 SLC7A11 ABCA7

1.82e-0410746812GO:0098657
GeneOntologyBiologicalProcessL-alpha-amino acid transmembrane transport

SLC38A1 SLC38A4 TTYH3 SLC7A11

1.96e-0487684GO:1902475
GeneOntologyBiologicalProcessorganophosphate ester transport

MFSD2A ABCA1 ABCA4 ABCA7 SLC35B1

1.96e-04162685GO:0015748
GeneOntologyBiologicalProcesscholesterol metabolic process

ABCA1 ABCA2 LIPA NPC1L1 HMGCR

2.02e-04163685GO:0008203
GeneOntologyBiologicalProcessregulation of inositol trisphosphate biosynthetic process

LHCGR POU1F1

2.23e-047682GO:0032960
GeneOntologyBiologicalProcesspositive regulation of inositol trisphosphate biosynthetic process

LHCGR POU1F1

2.23e-047682GO:0032962
GeneOntologyBiologicalProcessapolipoprotein A-I-mediated signaling pathway

ABCA1 ABCA7

2.23e-047682GO:0038027
GeneOntologyBiologicalProcesssteroid metabolic process

LHCGR ABCA1 ABCA2 LIPA NPC1L1 HMGCR HSD11B2

2.36e-04376687GO:0008202
GeneOntologyBiologicalProcesslipid transport

LHCGR MFSD2A ABCA1 ABCA2 LIPA ABCA4 NPC1L1 ABCA7

2.52e-04506688GO:0006869
GeneOntologyBiologicalProcessblood circulation

SLC6A4 KAT2B ADRA1D CYSLTR1 ASB3 FSHR HMGCR HSD11B2 CDC42

2.66e-04648689GO:0008015
GeneOntologyBiologicalProcesssecondary alcohol metabolic process

ABCA1 ABCA2 LIPA NPC1L1 HMGCR

2.88e-04176685GO:1902652
GeneOntologyBiologicalProcessnegative regulation of centriole replication

KAT2B KAT2A

2.96e-048682GO:0046600
GeneOntologyBiologicalProcesssterol metabolic process

ABCA1 ABCA2 LIPA NPC1L1 HMGCR

2.96e-04177685GO:0016125
GeneOntologyBiologicalProcessregulation of phospholipid metabolic process

MFSD2A ABCA2 BSCL2

3.10e-0440683GO:1903725
GeneOntologyBiologicalProcesssmall molecule biosynthetic process

SLC38A1 LHCGR KAT2B ABCA2 LIPA NPC1L1 POU1F1 HMGCR KAT2A

3.62e-04676689GO:0044283
GeneOntologyBiologicalProcessregulation of plasma lipoprotein particle levels

MFSD2A ABCA1 LIPA ABCA7

3.74e-04103684GO:0097006
GeneOntologyBiologicalProcesscarboxylic acid transport

SLC38A1 LHCGR MFSD2A SLC16A2 SLC38A4 TTYH3 SLC7A11

3.98e-04410687GO:0046942
GeneOntologyBiologicalProcesspositive regulation of carbohydrate metabolic process

LHCGR KAT2B POU1F1 KAT2A

4.02e-04105684GO:0045913
GeneOntologyBiologicalProcessorganic acid transport

SLC38A1 LHCGR MFSD2A SLC16A2 SLC38A4 TTYH3 SLC7A11

4.10e-04412687GO:0015849
GeneOntologyBiologicalProcessphospholipid transport

MFSD2A ABCA1 ABCA4 ABCA7

4.17e-04106684GO:0015914
GeneOntologyBiologicalProcessL-amino acid transport

SLC38A1 SLC38A4 TTYH3 SLC7A11

4.47e-04108684GO:0015807
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

SLC38A1 SLC6A4 GABRG1 LHCGR SLC2A10 KCNA10 SLC38A4 ATP2C2 ABCB6 TTYH3 ITPR2

4.60e-0410176811GO:0098660
GeneOntologyBiologicalProcessregulation of tube diameter

SLC6A4 KAT2B ADRA1D CYSLTR1 HMGCR

5.42e-04202685GO:0035296
GeneOntologyBiologicalProcessblood vessel diameter maintenance

SLC6A4 KAT2B ADRA1D CYSLTR1 HMGCR

5.42e-04202685GO:0097746
GeneOntologyBiologicalProcessregulation of tube size

SLC6A4 KAT2B ADRA1D CYSLTR1 HMGCR

5.54e-04203685GO:0035150
GeneOntologyBiologicalProcessregulation of small molecule metabolic process

LHCGR MFSD2A KAT2B ABCA2 POU1F1 KAT2A SLC7A11

5.58e-04434687GO:0062012
GeneOntologyBiologicalProcessinositol trisphosphate biosynthetic process

LHCGR POU1F1

5.78e-0411682GO:0032959
GeneOntologyBiologicalProcesssteroid biosynthetic process

LHCGR ABCA2 LIPA NPC1L1 HMGCR

6.32e-04209685GO:0006694
GeneOntologyBiologicalProcessvasoconstriction

SLC6A4 ADRA1D CYSLTR1 HMGCR

6.87e-04121684GO:0042310
GeneOntologyBiologicalProcessinternal peptidyl-lysine acetylation

KAT2B KAT2A

6.92e-0412682GO:0018393
GeneOntologyBiologicalProcesspositive regulation of vasoconstriction

ADRA1D CYSLTR1 HMGCR

7.54e-0454683GO:0045907
GeneOntologyBiologicalProcessmodified amino acid metabolic process

TPO MFSD2A SLC16A2 VNN2 SLC7A11

7.65e-04218685GO:0006575
GeneOntologyBiologicalProcessmembrane organization

MFSD2A ABCA1 ABCA2 MAL ABCA4 RER1 HUWE1 CDC42 SLC7A11 ABCA7

7.83e-049146810GO:0061024
GeneOntologyBiologicalProcessplasma lipoprotein particle organization

MFSD2A ABCA1 ABCA7

7.95e-0455683GO:0071827
GeneOntologyBiologicalProcessnegative regulation of centrosome cycle

KAT2B KAT2A

8.16e-0413682GO:0046606
GeneOntologyBiologicalProcessnegative regulation of centrosome duplication

KAT2B KAT2A

8.16e-0413682GO:0010826
GeneOntologyBiologicalProcesshigh-density lipoprotein particle assembly

ABCA1 ABCA7

8.16e-0413682GO:0034380
GeneOntologyBiologicalProcessvitamin transport

SLC2A10 NPC1L1 SLC52A3

8.38e-0456683GO:0051180
GeneOntologyBiologicalProcessregulation of cholesterol efflux

ABCA1 ABCA2 ABCA7

8.38e-0456683GO:0010874
GeneOntologyBiologicalProcessassociative learning

SLC6A4 HMGCR SLC7A11 ABCA7

8.98e-04130684GO:0008306
GeneOntologyBiologicalProcessregulation of carbohydrate biosynthetic process

LHCGR KAT2B POU1F1 KAT2A

9.51e-04132684GO:0043255
GeneOntologyBiologicalProcessimport across plasma membrane

SLC38A1 SLC2A10 SLC16A2 SLC38A4 SLC7A11

9.72e-04230685GO:0098739
GeneOntologyBiologicalProcessprotein-lipid complex organization

MFSD2A ABCA1 ABCA7

9.76e-0459683GO:0071825
GeneOntologyBiologicalProcessvitamin metabolic process

LIPA VNN2 NPC1L1 SLC52A3

9.78e-04133684GO:0006766
GeneOntologyBiologicalProcessneutral amino acid transport

SLC38A1 SLC38A4 SLC7A11

1.03e-0360683GO:0015804
GeneOntologyBiologicalProcessinternal protein amino acid acetylation

KAT2B KAT2A

1.09e-0315682GO:0006475
GeneOntologyBiologicalProcessphospholipid efflux

ABCA1 ABCA7

1.09e-0315682GO:0033700
GeneOntologyBiologicalProcessglycoprotein biosynthetic process

SLC2A10 ABCA2 GCNT1 ALG6 ABCA7 STT3B

1.14e-03357686GO:0009101
GeneOntologyBiologicalProcesspositive regulation of inositol phosphate biosynthetic process

LHCGR POU1F1

1.25e-0316682GO:0060732
GeneOntologyBiologicalProcessregulation of alcohol biosynthetic process

LHCGR ABCA2 POU1F1

1.29e-0365683GO:1902930
GeneOntologyBiologicalProcessregulation of lipid biosynthetic process

LHCGR MFSD2A KAT2B ABCA2 BSCL2

1.31e-03246685GO:0046890
GeneOntologyBiologicalProcessisoprenoid metabolic process

LIPA ABCA4 HMGCR ALG6

1.31e-03144684GO:0006720
GeneOntologyBiologicalProcessinositol trisphosphate metabolic process

LHCGR POU1F1

1.41e-0317682GO:0032957
GeneOntologyBiologicalProcessCdc42 protein signal transduction

ABCA1 CDC42

1.41e-0317682GO:0032488
GeneOntologyBiologicalProcesslearning or memory

SLC6A4 KAT2B HMGCR KAT2A SLC7A11 ABCA7

1.43e-03373686GO:0007611
GeneOntologyBiologicalProcessresponse to abiotic stimulus

SLC6A4 LIPA ABCA4 CYSLTR1 HMGCR HSD11B2 MYO15A GRM8 SLC7A11 ABCA7 ITPR2 SLC52A3

1.51e-0313616812GO:0009628
GeneOntologyBiologicalProcesspolyol biosynthetic process

LHCGR ABCA2 POU1F1

1.54e-0369683GO:0046173
GeneOntologyBiologicalProcessregulation of glycoprotein biosynthetic process

SLC2A10 ABCA2 ABCA7

1.54e-0369683GO:0010559
GeneOntologyBiologicalProcessphagocytosis, engulfment

ABCA1 CDC42 ABCA7

1.54e-0369683GO:0006911
GeneOntologyBiologicalProcessregulation of inositol phosphate biosynthetic process

LHCGR POU1F1

1.58e-0318682GO:0010919
GeneOntologyBiologicalProcessalanine transport

SLC38A1 SLC38A4

1.58e-0318682GO:0032328
GeneOntologyBiologicalProcessmonoatomic anion transmembrane transport

GABRG1 GPR89B GPR89A TTYH3

1.64e-03153684GO:0098656
GeneOntologyBiologicalProcessmaintenance of location

LHCGR ABCA1 LIPA RER1 BSCL2 ITPR2

1.94e-03396686GO:0051235
GeneOntologyBiologicalProcessregulation of amyloid-beta clearance

HMGCR ABCA7

1.96e-0320682GO:1900221
GeneOntologyBiologicalProcesscarboxylic acid transmembrane transport

SLC38A1 SLC38A4 TTYH3 SLC7A11

2.07e-03163684GO:1905039
GeneOntologyCellularComponentendoplasmic reticulum membrane

MFSD2A ABCA1 THADA OR10J5 ABCB6 HMGCR BSCL2 HSD11B2 CDC42 ALG6 OR7A2P TMEM50B STT3B SLC35B1 ITPR2

1.64e-0512936915GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

MFSD2A ABCA1 THADA OR10J5 ABCB6 HMGCR BSCL2 HSD11B2 CDC42 ALG6 OR7A2P TMEM50B STT3B SLC35B1 ITPR2

1.73e-0512996915GO:0098827
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

MFSD2A ABCA1 THADA OR10J5 ABCB6 HMGCR BSCL2 HSD11B2 CDC42 ALG6 OR7A2P TMEM50B STT3B SLC35B1 ITPR2

2.22e-0513276915GO:0042175
GeneOntologyCellularComponentGolgi membrane

GPR89B ATP2C2 GPR89A RER1 ABCB6 GCNT1 HUWE1 CDC42 ABCA7 TMEM50B SLC35B1

2.24e-057216911GO:0000139
GeneOntologyCellularComponentATP-binding cassette (ABC) transporter complex

ABCA2 ABCB6

1.60e-046692GO:0043190
GeneOntologyCellularComponentapical part of cell

SLC38A1 MAL SLC16A2 NPC1L1 CDC42 SLC7A11 ABCA7 SLC52A3

7.22e-04592698GO:0045177
GeneOntologyCellularComponentATAC complex

KAT2B KAT2A

9.52e-0414692GO:0140672
GeneOntologyCellularComponenttransmembrane transporter complex

GABRG1 GPR89B ABCA2 KCNA10 GPR89A ABCB6 TTYH3

1.67e-03523697GO:1902495
MousePhenoabnormal vesicle-mediated transport

MFSD2A ABCA1 RASA4 MRGPRX2 RASA4B PTGDR

3.98e-05156576MP:0008546
MousePhenoabnormal circulating lipid level

TPO PCSK2 MFSD2A KAT2B ABCA1 LIPA TMEM248 SLC16A2 NPC1L1 HMGCR BSCL2 HSD11B2 CDC42 ABCA7 STT3B SLC52A3

4.37e-0513055716MP:0003949
MousePhenoabnormal circulating HDL cholesterol level

PCSK2 KAT2B ABCA1 LIPA SLC16A2 NPC1L1 BSCL2 CDC42 ABCA7

9.24e-05460579MP:0000184
MousePhenoabnormal circulating cholesterol level

TPO PCSK2 KAT2B ABCA1 LIPA TMEM248 SLC16A2 NPC1L1 BSCL2 CDC42 ABCA7 STT3B

9.70e-058235712MP:0000180
MousePhenodecreased ovary secretion

LHCGR FSHR

9.75e-054572MP:0014270
MousePhenoabnormal cholesterol level

TPO PCSK2 KAT2B ABCA1 LIPA TMEM248 SLC16A2 NPC1L1 BSCL2 CDC42 ABCA7 STT3B

1.59e-048675712MP:0003947
MousePhenoabnormal sterol level

TPO PCSK2 KAT2B ABCA1 LIPA TMEM248 SLC16A2 NPC1L1 BSCL2 CDC42 ABCA7 STT3B

1.83e-048805712MP:0012224
MousePhenodecreased hormone level

SLC6A4 LHCGR PCSK2 ABCA1 SLC16A2 FSHR POU1F1 BSCL2 HSD11B2 SLC7A11

2.18e-046355710MP:0014455
MousePhenoabnormal pituitary hormone level

TPO LHCGR PCSK2 SLC16A2 FSHR POU1F1

2.27e-04214576MP:0003965
MousePhenoabnormal circulating lipoprotein level

PCSK2 KAT2B ABCA1 LIPA SLC16A2 NPC1L1 BSCL2 CDC42 ABCA7

2.80e-04533579MP:0010330
MousePhenoabnormal lipoprotein level

PCSK2 KAT2B ABCA1 LIPA SLC16A2 NPC1L1 BSCL2 CDC42 ABCA7

2.80e-04533579MP:0010329
MousePhenoabnormal tectorial membrane morphology

TPO POU1F1 MYO15A

2.93e-0432573MP:0003149
MousePhenoabnormal cholesterol homeostasis

TPO PCSK2 KAT2B ABCA1 LIPA TMEM248 SLC16A2 NPC1L1 BSCL2 CDC42 ABCA7 STT3B

3.23e-049365712MP:0005278
MousePhenodecreased circulating HDL cholesterol level

KAT2B ABCA1 LIPA SLC16A2 NPC1L1 ABCA7

3.35e-04230576MP:0000186
MousePhenoabnormal ovary secretion

LHCGR FSHR

3.39e-047572MP:0002783
MousePhenoenlarged adrenal glands

LHCGR ABCA1 TMEM248

3.52e-0434573MP:0000642
MousePhenodecreased circulating progesterone level

LHCGR ABCA1 FSHR

4.17e-0436573MP:0005185
MousePhenodecreased circulating estradiol level

LHCGR ABCA1 FSHR

4.90e-0438573MP:0005181
DomainABC_A

ABCA1 ABCA2 ABCA4 ABCA7

6.48e-0812654IPR026082
DomainABC_transporter_CS

ABCA1 ABCA2 ABCA4 ABCB6 ABCA7

3.36e-0742655IPR017871
DomainABC_tran

ABCA1 ABCA2 ABCA4 ABCB6 ABCA7

6.66e-0748655PF00005
DomainABC_TRANSPORTER_2

ABCA1 ABCA2 ABCA4 ABCB6 ABCA7

6.66e-0748655PS50893
DomainABC_TRANSPORTER_1

ABCA1 ABCA2 ABCA4 ABCB6 ABCA7

7.40e-0749655PS00211
DomainABC_transporter-like

ABCA1 ABCA2 ABCA4 ABCB6 ABCA7

8.20e-0750655IPR003439
DomainPCAF_N

KAT2B KAT2A

1.19e-052652IPR009464
DomainHist_acetylase_PCAF

KAT2B KAT2A

1.19e-052652IPR016376
DomainPCAF_N

KAT2B KAT2A

1.19e-052652PF06466
Domain-

RASA4 RASA4B

3.57e-0536524.10.1130.10
DomainTM_Fragile-X-F-assoc

TMEM185B TMEM185A

7.12e-054652IPR019396
DomainTmemb_185A

TMEM185B TMEM185A

7.12e-054652PF10269
DomainSterol-sensing

NPC1L1 HMGCR

1.18e-045652PF12349
DomainAAA+_ATPase

ABCA1 ABCA2 ABCA4 ABCB6 ABCA7

1.45e-04144655IPR003593
DomainAAA

ABCA1 ABCA2 ABCA4 ABCB6 ABCA7

1.45e-04144655SM00382
DomainGphrmn_rcpt_fam

LHCGR FSHR

1.77e-046652IPR002131
DomainBTK

RASA4 RASA4B

4.23e-049652SM00107
DomainZnf_Btk_motif

RASA4 RASA4B

4.23e-049652IPR001562
DomainBTK

RASA4 RASA4B

4.23e-049652PF00779
DomainZF_BTK

RASA4 RASA4B

4.23e-049652PS51113
DomainLRR_5

LHCGR FSHR

5.27e-0410652PF13306
DomainLRR_5

LHCGR FSHR

5.27e-0410652IPR026906
DomainSSD

NPC1L1 HMGCR

9.08e-0413652IPR000731
DomainSSD

NPC1L1 HMGCR

9.08e-0413652PS50156
DomainRasGAP

RASA4 RASA4B

1.06e-0314652SM00323
DomainRasGAP_CS

RASA4 RASA4B

1.06e-0314652IPR023152
DomainRasGAP

RASA4 RASA4B

1.22e-0315652PF00616
DomainRAS_GTPASE_ACTIV_1

RASA4 RASA4B

1.22e-0315652PS00509
DomainRAS_GTPASE_ACTIV_2

RASA4 RASA4B

1.22e-0315652PS50018
DomainMFS_dom

SLC2A10 MFSD2A SLC16A2 SLC15A5

1.22e-03134654IPR020846
Domain-

RASA4 RASA4B

1.39e-03166521.10.506.10
DomainAa_trans

SLC38A1 SLC38A4

1.57e-0317652PF01490
DomainAA_transpt_TM

SLC38A1 SLC38A4

1.57e-0317652IPR013057
DomainRasGAP_dom

RASA4 RASA4B

1.76e-0318652IPR001936
DomainGPCR_Rhodpsn_7TM

LHCGR ADRA1D OR10J5 CYSLTR1 GPR75 FSHR MRGPRX2 PTGDR

2.19e-03670658IPR017452
Domain7tm_1

LHCGR ADRA1D OR10J5 CYSLTR1 GPR75 FSHR MRGPRX2 PTGDR

2.33e-03677658PF00001
DomainGPCR_3

GPRC5D GRM8

2.40e-0321652IPR000337
DomainG_PROTEIN_RECEP_F1_1

LHCGR ADRA1D OR10J5 CYSLTR1 GPR75 FSHR MRGPRX2 PTGDR

2.51e-03685658PS00237
Domain7tm_3

GPRC5D GRM8

2.63e-0322652PF00003
DomainG_PROTEIN_RECEP_F3_2

GPRC5D GRM8

2.63e-0322652PS00980
DomainG_PROTEIN_RECEP_F3_3

GPRC5D GRM8

2.63e-0322652PS00981
DomainG_PROTEIN_RECEP_F3_1

GPRC5D GRM8

2.63e-0322652PS00979
DomainG_PROTEIN_RECEP_F3_4

GPRC5D GRM8

2.63e-0322652PS50259
DomainGPCR_3_C

GPRC5D GRM8

2.63e-0322652IPR017978
DomainG_PROTEIN_RECEP_F1_2

LHCGR ADRA1D OR10J5 CYSLTR1 GPR75 FSHR MRGPRX2 PTGDR

2.65e-03691658PS50262
DomainGPCR_Rhodpsn

LHCGR ADRA1D OR10J5 CYSLTR1 GPR75 FSHR MRGPRX2 PTGDR

2.67e-03692658IPR000276
DomainAcetyltransf_1

KAT2B KAT2A

2.88e-0323652PF00583
DomainGNAT

KAT2B KAT2A

3.40e-0325652PS51186
DomainGNAT_dom

KAT2B KAT2A

3.40e-0325652IPR000182
PathwayKEGG_ABC_TRANSPORTERS

ABCA1 ABCA2 ABCA4 ABCB6 ABCA7

1.13e-0644605M11911
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC38A1 SLC2A10 ABCA1 ABCA2 LIPA ABCA4 SLC16A2 SLC38A4 ATP2C2 ABCB6 TTYH3 SLC7A11 ABCA7

4.39e-066816013MM14985
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC38A1 SLC2A10 ABCA1 ABCA2 LIPA ABCA4 SLC16A2 SLC38A4 ATP2C2 ABCB6 TTYH3 SLC7A11 ABCA7

1.02e-057366013M27287
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

LHCGR ADRA1D OR10J5 CYSLTR1 FSHR PTGDR OR7A2P

1.33e-05186607MM15994
PathwayKEGG_MEDICUS_REFERENCE_GPCR_PLCB_ITPR_SIGNALING_PATHWAY

LHCGR ADRA1D CYSLTR1 ITPR2

5.90e-0550604M47951
PathwayWP_GPCRS_NONODORANT

LHCGR ADRA1D CYSLTR1 FSHR GPRC5D PTGDR GRM8

1.29e-04266607MM15843
PathwayKEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION

GABRG1 LHCGR ADRA1D CYSLTR1 FSHR PTGDR GRM8

1.49e-04272607M13380
PathwayWP_CHOLESTEROL_METABOLISM

ABCA1 LIPA NPC1L1 HMGCR

2.46e-0472604M46457
PathwayREACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE

SLC38A1 SLC38A4 SLC7A11

3.33e-0432603MM14957
PathwayREACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE

SLC38A1 SLC38A4 SLC7A11

3.65e-0433603M188
PathwayWP_ENTEROCYTE_CHOLESTEROL_METABOLISM

ABCA1 NPC1L1 HMGCR

4.74e-0436603M48067
PathwayWP_GPCRS_ODORANT

GPR89B GPR75 GPR89A MRGPRX2 OR7A2P

5.36e-04157605MM15872
PathwayWP_GPCRS_OTHER

ADRA1D FSHR GRM8 ALG6

6.53e-0493604M39629
PathwayREACTOME_RUNX3_REGULATES_NOTCH_SIGNALING

KAT2B KAT2A

7.84e-0410602MM15535
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

LHCGR ADRA1D CYSLTR1 GPR75 FSHR PTGDR

8.08e-04260606M39397
PathwayREACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT

ABCA2 ABCA4 ABCB6 ABCA7

8.26e-0499604MM14986
PathwayKEGG_MEDICUS_REFERENCE_N_GLYCAN_PRECURSOR_BIOSYNTHESIS_ALG6_TO_OST

ALG6 STT3B

9.56e-0411602M47614
PathwayREACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT

ABCA2 ABCA4 ABCB6 ABCA7

9.58e-04103604M758
PathwayREACTOME_HORMONE_LIGAND_BINDING_RECEPTORS

LHCGR FSHR

1.14e-0312602M13070
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

SLC38A1 GPR89B ABCA2 THADA TMEM248 PES1 RER1 HMGCR BSCL2 GCNT1 SLC7A11 ALG6 ABCA7 DNASE2 STT3B ITPR2

1.27e-091201691635696571
Pubmed

Differential phospholipid substrates and directional transport by ATP-binding cassette proteins ABCA1, ABCA7, and ABCA4 and disease-causing mutants.

ABCA1 ABCA4 ABCA7

7.47e-09369324097981
Pubmed

P/CAF and GCN5 acetylate the AML1/MDS1/EVI1 fusion oncoprotein.

KAT2B KAT2A HSD11B2

2.99e-08469312878208
Pubmed

Genome-wide association study identifies susceptibility loci for polycystic ovary syndrome on chromosome 2p16.3, 2p21 and 9q33.3.

LHCGR THADA FSHR

2.60e-07769321151128
Pubmed

Endogenous β-glucocerebrosidase activity in Abca12⁻/⁻epidermis elevates ceramide levels after topical lipid application but does not restore barrier function.

ABCA1 ABCA2 ABCA7

4.16e-07869324293640
Pubmed

Altered placental function of 11beta-hydroxysteroid dehydrogenase 2 knockout mice.

SLC38A1 SLC38A4 HSD11B2

6.22e-07969318845627
Pubmed

Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome.

LHCGR THADA FSHR

2.11e-061369322885925
Pubmed

Blood-Brain Barrier: From Physiology to Disease and Back.

SLC38A1 SLC2A10 MFSD2A ABCA2 SLC16A2

2.20e-0610569530280653
Pubmed

Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.

ABCA1 ABCA2 LIPA ABCA4 ABCB6 ABCA7

2.42e-0619369619343046
Pubmed

Establishment and Dysfunction of the Blood-Brain Barrier.

SLC38A1 MFSD2A ABCA2 SLC16A2

3.57e-065269426590417
Pubmed

Mechanisms of gonadotropin desensitization.

LHCGR FSHR

3.88e-06269211988313
Pubmed

Transcriptional coactivator p300/CBP-associated factor and p300/CBP-associated factor type B are required for normal estrogen response of the mouse uterus.

KAT2B KAT2A

3.88e-06269215502373
Pubmed

Evidence for chromosome 2p16.3 polycystic ovary syndrome susceptibility locus in affected women of European ancestry.

LHCGR FSHR

3.88e-06269223118426
Pubmed

Analysis of pituitary gonadotropin concentration in blood serum and immunolocalization and immunoexpression of follicle stimulating hormone and luteinising hormone receptors in ovaries of postmenopausal women.

LHCGR FSHR

3.88e-06269222207559
Pubmed

Association of NPC1L1 and HMGCR Gene Polymorphisms with Major Adverse Cardiac and Cerebrovascular Events in Patients with Three-Vessel Disease.

NPC1L1 HMGCR

3.88e-06269233167740
Pubmed

Interaction between HMGCR and ABCA1 cholesterol-related genes modulates Alzheimer's disease risk.

ABCA1 HMGCR

3.88e-06269219446537
Pubmed

Effect of naturally random allocation to lower low-density lipoprotein cholesterol on the risk of coronary heart disease mediated by polymorphisms in NPC1L1, HMGCR, or both: a 2 × 2 factorial Mendelian randomization study.

NPC1L1 HMGCR

3.88e-06269225770315
Pubmed

ATP-binding cassette transporter 1 (ABCA1) deficiency decreases platelet reactivity and reduces thromboxane A2 production independently of hematopoietic ABCA1.

ABCA1 ABCA7

3.88e-06269226749169
Pubmed

The small GTPase Cdc42 interacts with Niemann-Pick C1-like 1 (NPC1L1) and controls its movement from endocytic recycling compartment to plasma membrane in a cholesterol-dependent manner.

NPC1L1 CDC42

3.88e-06269221844200
Pubmed

ABCA2 is a strong genetic risk factor for early-onset Alzheimer's disease.

ABCA1 ABCA2

3.88e-06269215649702
Pubmed

Association of human follitropin (FSH) receptor with splicing variant of human lutropin/choriogonadotropin receptor negatively controls the expression of human FSH receptor.

LHCGR FSHR

3.88e-06269215890674
Pubmed

Cloning of two novel ABC transporters mapping on human chromosome 9.

ABCA1 ABCA2

3.88e-0626928088782
Pubmed

The effect of splice variant of the human luteinizing hormone (LH) receptor on the expression of gonadotropin receptor.

LHCGR FSHR

3.88e-06269217092637
Pubmed

The Luteinizing Hormone Receptor Knockout Mouse as a Tool to Probe the In Vivo Actions of Gonadotropic Hormones/Receptors in Females.

LHCGR FSHR

3.88e-06269233605422
Pubmed

CAPRI regulates Ca(2+)-dependent inactivation of the Ras-MAPK pathway.

RASA4 RASA4B

3.88e-06269211448776
Pubmed

A novel gene, FAM11A, associated with the FRAXF CpG island is transcriptionally silent in FRAXF full mutation.

TMEM185B TMEM185A

3.88e-06269212404111
Pubmed

Lysophosphatidylcholine export by human ABCA7.

ABCA1 ABCA7

3.88e-06269228373057
Pubmed

Associations of FSHR and LHCGR gene variants with ovarian reserve and clinical pregnancy rates.

LHCGR FSHR

3.88e-06269234391684
Pubmed

Preferential incorporation of shorter and less unsaturated acyl phospholipids into high density lipoprotein-like particles in the ABCA1- and ABCA7-mediated biogenesis with apoA-I.

ABCA1 ABCA7

3.88e-06269225665932
Pubmed

Distinct but overlapping roles of histone acetylase PCAF and of the closely related PCAF-B/GCN5 in mouse embryogenesis.

KAT2B KAT2A

3.88e-06269211027331
Pubmed

Divergent functions of histone acetyltransferases KAT2A and KAT2B in keratinocyte self-renewal and differentiation.

KAT2B KAT2A

3.88e-06269237259855
Pubmed

Alterations of the FSH and LH receptor genes and evaluation of sperm ultrastructure in men with idiopathic hypergonadotropic hypogonadism.

LHCGR FSHR

3.88e-06269223884663
Pubmed

Influenza A virus nucleoprotein is acetylated by histone acetyltransferases PCAF and GCN5.

KAT2B KAT2A

3.88e-06269229555684
Pubmed

Amyloid beta increases ABCA1 and HMGCR protein expression, and cholesterol synthesis and accumulation in mice neurons and astrocytes.

ABCA1 HMGCR

3.88e-06269234744007
Pubmed

Acetylation of the influenza A virus polymerase subunit PA in the N-terminal domain positively regulates its endonuclease activity.

KAT2B KAT2A

3.88e-06269234270849
Pubmed

Association of NPC1L1 and HMGCR gene polymorphisms with coronary artery calcification in patients with premature triple-vessel coronary disease.

NPC1L1 HMGCR

3.88e-06269238233830
Pubmed

GPHR-dependent functions of the Golgi apparatus are essential for the formation of lamellar granules and the skin barrier.

GPR89B GPR89A

3.88e-06269222572823
Pubmed

Reduced Gonadotrophin Receptor Expression Is Associated with a More Aggressive Ovarian Cancer Phenotype.

LHCGR FSHR

3.88e-06269233374698
Pubmed

ABC transporters: from microorganisms to man.

ABCA1 ABCA2

3.88e-0626921282354
Pubmed

Leutinizing hormone/choriogonadotropin receptor and follicle stimulating hormone receptor gene variants in polycystic ovary syndrome.

LHCGR FSHR

3.88e-06269225649397
Pubmed

HMGCR gene polymorphism is associated with residual cholesterol risk in premature triple-vessel disease patients treated with moderate-intensity statins.

NPC1L1 HMGCR

3.88e-06269237355634
Pubmed

Human ABCA7 supports apolipoprotein-mediated release of cellular cholesterol and phospholipid to generate high density lipoprotein.

ABCA1 ABCA7

3.88e-06269214570867
Pubmed

Constitutively active follicle-stimulating hormone receptor enables androgen-independent spermatogenesis.

LHCGR FSHR

3.88e-06269229584617
Pubmed

Intrinsic differences in the response of the human lutropin receptor versus the human follitropin receptor to activating mutations.

LHCGR FSHR

3.88e-06269217609213
Pubmed

The murine luteinizing hormone and follicle-stimulating hormone receptor genes: transcription initiation sites, putative promoter sequences and promoter activity.

LHCGR FSHR

3.88e-0626921459341
Pubmed

Heterogeneity of high density lipoprotein generated by ABCA1 and ABCA7.

ABCA1 ABCA7

3.88e-06269215930518
Pubmed

Targeting gonadotropin receptor genes: reproductive biology, aging, and related health implications.

LHCGR FSHR

3.88e-06269216034175
Pubmed

GPHR is a novel anion channel critical for acidification and functions of the Golgi apparatus.

GPR89B GPR89A

3.88e-06269218794847
Pubmed

An essential function for the calcium-promoted Ras inactivator in Fcgamma receptor-mediated phagocytosis.

RASA4 RASA4B

3.88e-06269216041389
Pubmed

Gonadotropin receptor polymorphisms (FSHR N680S and LHCGR N312S) are not predictive of clinical outcome and live birth in assisted reproductive technology.

LHCGR FSHR

3.88e-06269235842313
Pubmed

Heterodimerization between the lutropin and follitropin receptors is associated with an attenuation of hormone-dependent signaling.

LHCGR FSHR

3.88e-06269223825122
Pubmed

Cloning, characterization and tissue distribution of the rat ATP-binding cassette (ABC) transporter ABC2/ABCA2.

ABCA1 ABCA2

3.88e-06269210970803
Pubmed

Infertility and ovarian follicle reserve depletion are associated with dysregulation of the FSH and LH receptor density in human antral follicles.

LHCGR FSHR

3.88e-06269228188844
Pubmed

FSH and LH receptors are differentially expressed in cumulus cells surrounding developmentally competent and incompetent mouse fully grown antral oocytes.

LHCGR FSHR

3.88e-06269224476692
Pubmed

Evidence for expression and functionality of FSH and LH/hCG receptors in human endometrium.

LHCGR FSHR

3.88e-06269229974367
Pubmed

Combined assessment of polymorphisms in the LHCGR and FSHR genes predict chance of pregnancy after in vitro fertilization.

LHCGR FSHR

3.88e-06269226769719
Pubmed

Gcn5 and PCAF negatively regulate interferon-β production through HAT-independent inhibition of TBK1.

KAT2B KAT2A

3.88e-06269225269644
Pubmed

Differential Effects of Histone Acetyltransferase GCN5 or PCAF Knockdown on Urothelial Carcinoma Cells.

KAT2B KAT2A

3.88e-06269228678170
Pubmed

Triptorelin and cetrorelix induce immune responses and affect uterine development and expressions of genes and proteins of ESR1, LHR, and FSHR of mice.

LHCGR FSHR

1.16e-05369227075695
Pubmed

Genetic variants of the arachidonic acid pathway in non-steroidal anti-inflammatory drug-induced acute urticaria.

CYSLTR1 PTGDR

1.16e-05369223181793
Pubmed

Aetiological coding sequence variants in non-syndromic premature ovarian failure: From genetic linkage analysis to next generation sequencing.

LHCGR FSHR

1.16e-05369225960166
Pubmed

Association study between variants in LHCGR DENND1A and THADA with preeclampsia risk in Han Chinese populations.

LHCGR THADA

1.16e-05369229727258
Pubmed

LH (Trp8Arg/Ile15Thr), LHR (insLQ) and FSHR (Asn680Ser) polymorphisms genotypic prevalence in women with endometriosis and infertility.

LHCGR FSHR

1.16e-05369225935136
Pubmed

Genetic polymorphisms of GnRH and gonadotrophic hormone receptors affect the phenotype of polycystic ovary syndrome.

LHCGR FSHR

1.16e-05369219403562
Pubmed

Structural predictions for the ligand-binding region of glycoprotein hormone receptors and the nature of hormone-receptor interactions.

LHCGR FSHR

1.16e-0536928747461
Pubmed

Regulation of luteinizing hormone-receptor and follicle-stimulating hormone-receptor messenger ribonucleic acid levels during development in the neonatal mouse ovary.

LHCGR FSHR

1.16e-0536929282997
Pubmed

GCN5 inhibits XBP-1S-mediated transcription by antagonizing PCAF action.

KAT2B KAT2A

1.16e-05369225426559
Pubmed

CD28 inhibits T cell adhesion by recruiting CAPRI to the plasma membrane.

RASA4 RASA4B

1.16e-05369225637021
Pubmed

Tyrosine sulfation is required for agonist recognition by glycoprotein hormone receptors.

LHCGR FSHR

1.16e-05369211847099
Pubmed

Tat acetyl-acceptor lysines are important for human immunodeficiency virus type-1 replication.

KAT2B KAT2A

1.16e-05369211956210
Pubmed

Pooled genetic analysis identifies variants that confer enhanced susceptibility to PCOS in Indian ethnicity.

LHCGR THADA

1.16e-05369232416252
Pubmed

Ras homolog enriched in striatum inhibits the functional activity of wild type thyrotropin, follicle-stimulating hormone, luteinizing hormone receptors and activating thyrotropin receptor mutations by altering their expression in COS-7 cells.

LHCGR FSHR

1.16e-05369217556863
Pubmed

Glycoprotein hormone receptors: link between receptor homodimerization and negative cooperativity.

LHCGR FSHR

1.16e-05369215889138
Pubmed

The G-protein coupled estrogen receptor (GPER/GPR30) is a gonadotropin receptor dependent positive prognosticator in ovarian carcinoma patients.

LHCGR FSHR

1.16e-05369223951246
Pubmed

Acetylation of interferon regulatory factor-7 by p300/CREB-binding protein (CBP)-associated factor (PCAF) impairs its DNA binding.

KAT2B KAT2A

1.16e-05369212374802
Pubmed

Genetic and structural studies of RABL3 reveal an essential role in lymphoid development and function.

GPR89B GPR89A

1.16e-05369232220963
Pubmed

Acetylation of conserved lysines in the catalytic core of cyclin-dependent kinase 9 inhibits kinase activity and regulates transcription.

KAT2B KAT2A

1.16e-05369218250157
Pubmed

ATP-binding cassette transporters ABCA1, ABCA7, and ABCG1 in mouse spermatozoa.

ABCA1 ABCA7

1.16e-05369218793613
Pubmed

Effects of deletion of macrophage ABCA7 on lipid metabolism and the development of atherosclerosis in the presence and absence of ABCA1.

ABCA1 ABCA7

1.16e-05369222403608
Pubmed

Gene Expression in Granulosa Cells From Small Antral Follicles From Women With or Without Polycystic Ovaries.

LHCGR FSHR

1.16e-05369231276164
Pubmed

Expression of mRNA for the LH and FSH receptors in mouse oocytes and preimplantation embryos.

LHCGR FSHR

1.16e-05369211226072
Pubmed

KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification.

KAT2B KAT2A

1.16e-05369227796307
Pubmed

Association of gonadotropin receptor precursors with the protein folding chaperone calnexin.

LHCGR FSHR

1.16e-0536929528938
Pubmed

A genome-wide association study identified a novel genetic loci STON1-GTF2A1L/LHCGR/FSHR for bilaterality of neovascular age-related macular degeneration.

LHCGR FSHR

1.16e-05369228775256
Pubmed

Acetylation of TBX5 by KAT2B and KAT2A regulates heart and limb development.

KAT2B KAT2A

1.16e-05369229174768
Pubmed

In-vitro acetylation of SARS-CoV and SARS-CoV-2 nucleocapsid proteins by human PCAF and GCN5.

KAT2B KAT2A

1.16e-05369233894414
Pubmed

Potential role of ABCA7 in cellular lipid efflux to apoA-I.

ABCA1 ABCA7

1.16e-05369215520449
Pubmed

A threshold concentration of FSH is needed during IVM of ex vivo collected human oocytes.

LHCGR FSHR

1.16e-05369234050448
Pubmed

Reduced cholesterol absorption upon PPARdelta activation coincides with decreased intestinal expression of NPC1L1.

ABCA1 NPC1L1

1.16e-05369215604518
Pubmed

Antenatal dexamethasone treatment in midgestation reduces system A-mediated transport in the late-gestation murine placenta.

SLC38A1 SLC38A4

1.16e-05369221733830
Pubmed

Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt.

SLC38A1 RER1 HMGCR HUWE1 CDC42 STT3B

1.68e-0527169625737280
Pubmed

The MEV mouse linkage testing stock: mapping 30 novel proviral insertions and establishment of an improved stock.

TPO POU1F1 HMGCR

2.11e-05276938390965
Pubmed

Intracellular interleukin-1alpha functionally interacts with histone acetyltransferase complexes.

KAT2B KAT2A

2.32e-05469214612453
Pubmed

Helical apolipoproteins of high-density lipoprotein enhance phagocytosis by stabilizing ATP-binding cassette transporter A7.

ABCA1 ABCA7

2.32e-05469220495215
Pubmed

Critical role of histone acetylation by p300 in human placental 11β-HSD2 expression.

KAT2B HSD11B2

2.32e-05469223714681
Pubmed

Influence of mutations affecting gonadotropin production or responsiveness on expression of inhibin subunit mRNA and protein in the mouse ovary.

LHCGR FSHR

2.32e-05469215232063
Pubmed

Ca2+-dependent monomer and dimer formation switches CAPRI Protein between Ras GTPase-activating protein (GAP) and RapGAP activities.

RASA4 RASA4B

2.32e-05469221460216
Pubmed

Deoxyribonuclease II: structure and chromosomal localization of the murine gene, and comparison with the genomic structure of the human and three C. elegans homologs.

MAST1 DNASE2

2.32e-05469210903447
Pubmed

Amino acid transporter ATA2 is stored at the trans-Golgi network and released by insulin stimulus in adipocytes.

SLC38A1 SLC38A4

2.32e-05469217050538
Pubmed

Glucocorticoid-stimulated preadipocyte differentiation is mediated through acetylation of C/EBPbeta by GCN5.

KAT2B KAT2A

2.32e-05469217301242
InteractionHSD11B2 interactions

KAT2B KAT2A HSD11B2

2.65e-069653int:HSD11B2
InteractionCANX interactions

SLC38A1 SLC6A4 LHCGR ABCA2 LIPA TMEM248 VNN2 FSHR RER1 HMGCR BSCL2 HUWE1 CDC42 DNASE2 STT3B

8.67e-0612616515int:CANX
InteractionCCR6 interactions

GPR89A RER1 HMGCR TTYH3 ITPR2

1.01e-0589655int:CCR6
InteractionTRARG1 interactions

SLC38A1 TMEM248 SLC16A2 GPRC5D BSCL2

2.94e-05111655int:TRARG1
InteractionGPR17 interactions

THADA INTS2 CYSLTR1 GPR89A HMGCR TTYH3 ITPR2

3.47e-05283657int:GPR17
InteractionVIPR1 interactions

THADA INTS2 GPR89A RER1 HMGCR TTYH3

5.16e-05205656int:VIPR1
InteractionDPEP1 interactions

INTS2 RER1 ABCB6 ALG6

5.41e-0564654int:DPEP1
CytobandEnsembl 112 genes in cytogenetic band chr2p16

LHCGR GPR75 ASB3 FSHR

3.48e-05121694chr2p16
Cytoband12p13.3

CD163L1 GPRC5D

9.42e-043069212p13.3
Cytoband2p21

LHCGR THADA

3.85e-03616922p21
Cytoband1q21.1

GPR89B GPR89A

3.97e-03626921q21.1
GeneFamilyATP binding cassette subfamily A

ABCA1 ABCA2 ABCA4 ABCA7

5.50e-0814514805
GeneFamilySolute carriers

SLC38A1 SLC6A4 SLC2A10 SLC16A2 SLC38A4 SLC15A5 SLC7A11 SLC35B1 SLC52A3

1.40e-06395519752
GeneFamilyGlycoprotein hormone receptors

LHCGR FSHR

2.34e-053512199
GeneFamilyPleckstrin homology domain containing|SH2 domain containing|C2 and RasGAP domain containing

RASA4 RASA4B

3.46e-0410512830
GeneFamilyATAC complex

KAT2B KAT2A

5.97e-04135121058
GeneFamilyLysine acetyltransferases|ATAC complex|SAGA complex|GCN5 related N-acetyltransferases

KAT2B KAT2A

1.03e-03175121059
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

KAT2B KAT2A

1.03e-0317512486
GeneFamilyGCN5 related N-acetyltransferases

KAT2B KAT2A

2.07e-03245121134
CoexpressionBROWNE_HCMV_INFECTION_48HR_DN

LHCGR LIPA ABCA4 RASA4 ATP2C2 RER1 ABCB6 BSCL2 GRM8

4.20e-06482689M12144
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_DN

SLC38A1 SLC2A10 GPR89B LIPA TMEM248 SLC38A4 TMEM185A GPR89A RER1 HMGCR

1.29e-057036810MM1055
ToppCell10x5'v1-week_12-13-Myeloid_macrophage-stroma-stromal_macrophage|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ZMYND15 ABCA1 LIPA CD163L1 TTYH3 DNASE2 ITPR2

2.38e-08197697075044c17f1c52008cd3c292c15cbf485b50411e
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC38A1 MAL SLC38A4 NPC1L1 HSD11B2 SLC52A3

4.59e-07187696b7689e7f6511920cd2beff27389555fddf685f61
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC38A1 MAL SLC38A4 HSD11B2 TMEM50B SLC52A3

5.35e-07192696d5ec4cdb15620a5abfc83577353501186c2bc86a
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC38A1 MAL SLC38A4 HSD11B2 TMEM50B SLC52A3

5.52e-071936965da60321bcf761913eb30779b6d8b1e933c5e51e
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf|Thalamus / BrainAtlas - Mouse McCarroll V32

MAL FSHR GPRC5D HSD11B2

6.63e-06786945b45aacaff2a2b98c4ef8e7ac51ad482a69a1d8b
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf-Oligodendrocyte.Trf.Ctps_(Ctps)|Thalamus / BrainAtlas - Mouse McCarroll V32

MAL FSHR GPRC5D HSD11B2

6.63e-0678694afed2f358c8a33889931bc5ad8cb24f92323e6f8
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

SLC38A1 RASA4 HMGCR HUWE1 SLC7A11

1.01e-05185695a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellfacs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABCA1 ABCA4 SLC38A4 POU1F1 ABCB6

1.01e-0518569559acaf025353405948dc34ccccf37ec5c08ea903
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

SLC38A1 RASA4 HUWE1 SLC7A11 ITPR2

1.04e-051866958571956890fc9894d766ba294a28e376b4aba428
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-large_intestine_goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASA4 ATP2C2 HMGCR GCNT1 HSD11B2

1.04e-0518669532d30f08b20a0a28e38b37bd52ab26d1d43736ce
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC38A1 MAL SLC38A4 HSD11B2 SLC52A3

1.18e-051916957235a4d1601c88a2c8af571a2c04ab56d32f1b9a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC38A1 MAL SLC38A4 HSD11B2 SLC52A3

1.21e-0519269540f44ac4ab673ee6156abdd2074a60b9de3281ad
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC38A1 MAL HMGCR HSD11B2 SLC52A3

1.24e-0519369546d5d1f8150ebbc7f1941b96ab184491e5c1210b
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC38A1 MAL SLC38A4 HSD11B2 SLC52A3

1.24e-05193695d994b2f2707877288f88cab7cd6002ef91962c50
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA1 LIPA CD163L1 TTYH3 ITPR2

1.27e-051946958e2819a9d0529f7b2de1a7c1190575175d6173ee
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA1 LIPA CD163L1 TTYH3 ITPR2

1.30e-05195695c16479a10f5ca2e89aea1742dbc5cc4dc9f3ea88
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC38A1 MAL HMGCR HSD11B2 SLC52A3

1.34e-05196695142fd80ff74979cc2f9088fc3fcbfed374afb973
ToppCell10x3'2.3-week_14-16-Myeloid_macrophage-stroma-stromal_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ABCA1 LIPA CD163L1 TTYH3 DNASE2

1.37e-0519769572775eb6c24cfb956436642ac9cd6e4d5c01ea5f
ToppCell10x5'v1-week_17-19-Myeloid_macrophage-stroma-stromal_macrophage|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ABCA1 LIPA CD163L1 TTYH3 DNASE2

1.44e-051996952649afa3ccda78e9d1df26127b66cbfa0c6cd01d
ToppCell10x5'v1-week_14-16-Myeloid_macrophage-stroma-stromal_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ZMYND15 ABCA1 LIPA CD163L1 TTYH3

1.47e-05200695af743dfef7e7cfaef1c494999757123f93a213e3
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC38A1 RASA4 CD163L1 GCNT1

6.82e-05141694d3ce2218bfa9750795d920e1ef162ea44efb2e66
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Adora2a-Excitatory_Neuron.Gad1Gad2.Adora2a-Nnat_(iSPN)|Striatum / BrainAtlas - Mouse McCarroll V32

TPO KCNA10 CD163L1

8.10e-0554693d21611ae38d34d62f855fa3797eb37a5d287a4a5
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Adora2a-Excitatory_Neuron.Gad1Gad2.Adora2a-Nnat_(iSPN)-|Striatum / BrainAtlas - Mouse McCarroll V32

TPO KCNA10 CD163L1

8.10e-055469320309afadc500f1485e86c62d8d38168c9253539
ToppCellfacs-Trachea-nan-24m-Myeloid-granulocyte|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A4 MRGPRX2 GCNT1 SLC7A11

8.90e-0515169426fd55efb647c41436416d45952ee97b050e632c
ToppCellprimary_visual_cortex-Non-neuronal-astrocyte|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GABRG1 MFSD2A SLC7A11 ITPR2

9.36e-0515369495b28c5bd10ffb74c0993ebd565038b9818e4bd2
ToppCellprimary_visual_cortex-Non-neuronal-astrocyte-Astro|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GABRG1 MFSD2A SLC7A11 ITPR2

9.36e-05153694b09f8def40a1ea56722f3398f61a036667b61cd9
ToppCellprimary_visual_cortex-Non-neuronal-astrocyte-Astro-Astro_Aqp4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GABRG1 MFSD2A SLC7A11 ITPR2

9.36e-051536943ab9d55b3db51715c1d61eca142384195ce4b54f
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

SLC38A1 MAL RASA4B SLC7A11

1.01e-0415669419472ef1642c2ad333aa3ce3675a25c6ab1d4556
ToppCellfacs-Trachea-24m-Hematologic-myeloid-granulocyte|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC6A4 MRGPRX2 GCNT1 SLC7A11

1.03e-04157694188d2f85babcd4eefe20e7a392d851b2e1185bab
ToppCellfacs-Trachea-18m-Hematologic-myeloid-granulocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC6A4 MRGPRX2 GCNT1 SLC7A11

1.14e-04161694d1f2e5245c7c247b684f48f9f877e149a3ee7c06
ToppCellfacs-Trachea-3m-Hematologic-myeloid-granulocyte-granulocyte_l26|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC6A4 MRGPRX2 GCNT1 SLC52A3

1.25e-0416569423955e3373660f827518e723ac62fba99753f375
ToppCelldroplet-Limb_Muscle-nan-3m-Myeloid-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A1 SLC6A4 MRGPRX2 GCNT1

1.28e-041666940a7992bc673fca546636563ec3fc17a4298ab6b1
ToppCellfacs-Trachea-nan-18m-Myeloid-granulocyte|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A4 MRGPRX2 GCNT1 SLC7A11

1.28e-041666947f8b4cf63c3e292ae421f111edaa4572717f4db1
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAL SLC16A2 STT3B SLC52A3

1.34e-041686943bddf411a60137a8883fc9e77586e4719b0d6067
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAL SLC16A2 STT3B SLC52A3

1.34e-04168694b6d948857ee652351ddbe383b75fdd1721cd8721
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L3-5_THEMIS_UBE2F|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LIPA GCNT1 GRM8 SLC7A11

1.34e-04168694bfa1491e8d433933003778b274710d3a16d973cb
ToppCellfacs-Trachea-18m-Hematologic-myeloid-granulocyte-granulocyte_l26|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC6A4 MRGPRX2 GCNT1 SLC52A3

1.40e-041706944b1c84b35b7242a297ffdb9c23a6d982acf1bed5
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ATP2C2 FSHR SLC15A5 GRM8

1.40e-04170694ce2fd2fbbfd152290be0cf8e513f102fdc182b41
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ATP2C2 FSHR SLC15A5 GRM8

1.40e-04170694ab5c6a91c371e4df15b0842828dc55039695ab06
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2-Exc_L5-6_FEZF2_MYBPHL|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ATP2C2 FSHR SLC15A5 GRM8

1.40e-041706944aa9e597f6550ac8cac3137a98be58e71efd07d6
ToppCellfacs-Lung-EPCAM-18m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZMYND15 SLC6A4 RASA4 SLC7A11

1.47e-04172694c5caae0b21e35a2d5dcd898fbfa1ef33f92c019f
ToppCellfacs-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZMYND15 SLC6A4 RASA4 SLC7A11

1.47e-0417269448d0cfc37d1b1ae48ed8f8b2711abeb609d2bb6e
ToppCellfacs-Lung-EPCAM-18m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZMYND15 SLC6A4 RASA4 SLC7A11

1.47e-041726947c085c02b59e24e2a2cd393b5e692f9fb19257fe
ToppCellBronchial_Biopsy-Epithelial-Ionocytes|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

SLC6A4 MAL HSD11B2 ITPR2

1.54e-041746947e7b13de916cd4fa0fa6fb06e6b4942877afa9fb
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC38A1 ABCA2 PTGDR SLC7A11

1.57e-0417569426bd957498e41a3f1ffa60d3effa27ca8c4ba631
ToppCellBronchial_Biopsy-Epithelial-Ionocytes|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

SLC6A4 PCSK2 MAL ITPR2

1.57e-0417569413b8f7dc38c90b74d4a20a84a8705d8e2ec244f6
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZMYND15 ABCA1 MAST1 PCNX1

1.57e-04175694cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCellCV-Severe-7|CV / Virus stimulation, Condition and Cluster

SLC38A1 GPR89B HMGCR HUWE1

1.60e-041766943de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

SLC38A1 GPR89B HMGCR HUWE1

1.64e-0417769482fdd6185b368f54f03de389427cbe3071d21a99
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABCA1 MAL GCNT1 SLC52A3

1.64e-04177694d68132e145bd413404fdbe215b5dbe520e756e50
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-large_intestine_goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASA4 ATP2C2 GCNT1 HSD11B2

1.68e-0417869407d6d5275a4d17f8024fde74e92ab2505b4adfbf
ToppCellfrontal_cortex-Non-neuronal|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MFSD2A MAL SLC7A11 ITPR2

1.71e-04179694ef01478bd03eb00f0ff2b6a8ae9244687c5f85aa
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

MAL CYSLTR1 GCNT1

1.76e-047069337e34ef782b253c43628d5bb2fe5e0294573d0ef
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZMYND15 ABCA1 LIPA DNASE2

1.86e-04183694103c4c4595d8daa677679fd2fa1e99cd398e56dd
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-large_intestine_goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC2A10 RASA4 ATP2C2 HSD11B2

1.86e-041836945a936fb07074cec753bf19e3e3e52499605ea22c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC38A1 MAL HSD11B2 SLC52A3

1.86e-04183694d340ab5a77e8d819a1dfb4ca3e9a4b9bc988923c
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC2A10 RASA4 ATP2C2 HSD11B2

1.86e-0418369407c18ccc45ddc9c22e482bd9ffb87f46ebcfe473
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC38A1 MAL HSD11B2 SLC52A3

1.90e-041846949690d4290e70f9bda889754ffb30b0af1f7cb94b
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABCA1 CD163L1 GCNT1 ITPR2

1.94e-041856948207f9eff113eed429e961748c6b17d672a13b33
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC38A1 MAL HSD11B2 SLC52A3

1.94e-041856943d73b3e0bceb192257e5cfbe64b7ccb379b6e22d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC38A1 MAL HSD11B2 SLC52A3

1.98e-04186694d65fa6d8e8a195ea10cfde1499d096d6acf7a634
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC38A1 MAL HSD11B2 SLC52A3

1.98e-0418669408632045d499e61dd96ff29a5a9a208afe58dc58
ToppCellMyeloid-B_(Activated_Macrophage)|World / shred on cell class and cell subclass (v4)

LIPA SLC7A11 DNASE2 ITPR2

1.98e-0418669433d731a7883d75e4e7db83b641cdb1e9a39938bf
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SLC38A1 MFSD2A ATP2C2 HSD11B2

1.98e-04186694bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRG1 LHCGR TTYH3 SLC7A11

1.98e-04186694ac7a84b11b4550c4ac01eab370dc8ab88e4fb72b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC38A1 MAL HSD11B2 SLC52A3

1.98e-04186694b3358e0fa6d845c81e94d56c8575f016621d28ff
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SLC38A1 MFSD2A ATP2C2 HSD11B2

2.02e-04187694db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCellControl-T_cells|Control / group, cell type (main and fine annotations)

SLC38A1 KAT2B PCNX1 PTGDR

2.02e-04187694f4e8e0eba58da89b56587667555a5d4754e108c7
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA1 CD163L1 TTYH3 ITPR2

2.06e-04188694cb091912f9b627a78a8793a37df7f1de839f887f
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC38A1 MAL HSD11B2 CDC42

2.06e-0418869436459e5b91cbd7336a502d96b0dc37ca560ae4d6
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Undifferentiated_Pleomorphic_Sarcoma|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

PES1 RER1 GCNT1 CDC42

2.06e-041886943df5a5b645403914c4d0506e2d93f8a8a98e3fa6
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SLC38A1 GABRG1 ATP2C2 HSD11B2

2.11e-041896945d9da836ce4308b8458bb3be3871a0aca734b6cd
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC38A1 MAL HSD11B2 GRM8

2.11e-0418969490aae7e806882bebfad78a78e9a16cf56af3ecd4
ToppCellwk_20-22-Hematologic-Myeloid-APOE+_Mac2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ABCA1 LIPA CD163L1 TTYH3

2.11e-04189694e189ef6066f87177d758f0e3ed9a17e01031a391
ToppCellPCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SLC38A1 GABRG1 HSD11B2 GRM8

2.11e-04189694c8b8f860aaf6c73863cd79941db6b469c830ef06
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MFSD2A ABCA4 SLC7A11 SLC52A3

2.15e-0419069406bfb62b94b0faf467ef93d5bc5d08924c770098
ToppCell356C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

LIPA CD163L1 TTYH3 ITPR2

2.15e-04190694d541e076137cf7334bdb0ed69db2f9a27c668c65
ToppCell368C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|368C / Donor, Lineage, Cell class and subclass (all cells)

LIPA CD163L1 TTYH3 ITPR2

2.15e-04190694cbba3d94a4c3e0b0d14f3b7c60dba5d6e097c5e3
ToppCellPSB-critical-LOC-Epithelial-Ionocyte|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SLC6A4 MAL HSD11B2 ITPR2

2.19e-041916948f4637e801554e2343b974fe7794f01dd2151418
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA1 CD163L1 CYSLTR1 GCNT1

2.19e-0419169451f5af610983aa73b9f4ece6f27d281ebff89a04
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

SLC38A1 GPR89B HMGCR HUWE1

2.19e-041916949454f642c3621370fa23640b631301346b300950
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC38A1 MAL HSD11B2 SLC52A3

2.19e-0419169465083daf317f66556dc047eb19297dcbe9c70299
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC38A1 MAL HSD11B2 SLC52A3

2.19e-041916940a0719a0a49ae0099d61e22585ac74c10c24b4a2
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA1 CD163L1 CYSLTR1 GCNT1

2.19e-041916948fd6bdc9d2b1c8d364221d7bc68d03921b668ab5
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KAT2B MAL SLC7A11 ITPR2

2.19e-04191694f3158cedf67e3b90aa94ea1f61c72c33aaa2d5ba
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SLC38A1 ABCA4 CD163L1 SLC38A4

2.24e-041926945e709c0714e8eba27e03a6def0544256bedb3ced
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_CTGF^high_distal_(3)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SLC38A1 MFSD2A HSD11B2 SLC7A11

2.24e-0419269439804d9ddc67c1b41887752df2503389eae44a1a
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC38A1 HSD11B2 TMEM50B SLC52A3

2.24e-041926949e031bf93eb8757fdd0cc22f01b44e48f85532d5
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC38A1 HSD11B2 TMEM50B SLC52A3

2.24e-041926943d777d07878269b87ec7e1f06489cae7c989d633
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SLC38A1 ATP2C2 HSD11B2 GRM8

2.24e-04192694d3634574b2e8d2ded6446969361b70761b331aea
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SLC38A1 ABCA4 CD163L1 SLC38A4

2.24e-041926945f4f44f15d3a2846981e68296643a4634930a211
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SLC38A1 ATP2C2 HSD11B2 GRM8

2.24e-041926941aa5e4d9b32013a3f272561dcb8377f6805706df
ToppCellControl-Myeloid-Monocyte-derived_macrophages|Control / group, cell type (main and fine annotations)

ABCA1 CD163L1 TTYH3 ITPR2

2.28e-04193694a6b3bd01e585e2e3fbe9bf693a2e385773123f8e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC38A1 SLC38A4 HSD11B2 SLC52A3

2.33e-04194694be869e186386d03ebb670971dd24fa656b4b0edf
ToppCell3'-Child04-06-SmallIntestine-Epithelial-goblet-Goblet_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC2A10 ABCA4 ATP2C2 HSD11B2

2.33e-0419469449cc5f5de4380302100e8cd937f08abe317ac75e
ToppCell3'-Child04-06-SmallIntestine-Epithelial-goblet|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC2A10 ABCA4 ATP2C2 HSD11B2

2.33e-04194694fb935df966c451e659b8bde281f8aebcb632f6cf
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC38A1 SLC38A4 HSD11B2 SLC52A3

2.33e-041946944d6c9b016e3a0641954a8ea10c97d1cd76fadd9f
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA1 LIPA CD163L1 TTYH3

2.33e-04194694ad72be9f6871b334e1f477d868c15e7792fadea5
ToppCellControl-Myeloid-Macrophage|World / Disease state, Lineage and Cell class

ABCA1 CD163L1 TTYH3 SLC7A11

2.33e-04194694c35bf04d5e7450cb6679a036fcabb1b28f409f29
ToppCell368C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

RASA4 CD163L1 TTYH3 ITPR2

2.33e-0419469458046894446cb250814252a23f60fdd59c114d77
DrugOrg 41841

TPO LHCGR FSHR

2.43e-075673ctd:C510603
Drugtrilinolein

ABCA1 NPC1L1 HMGCR

8.45e-077673ctd:C009564
Drugtrilinolenin

ABCA1 NPC1L1 HMGCR

8.45e-077673ctd:C101314
Drugforskolin from Coleus forskohlii

SLC38A1 TPO GABRG1 LHCGR SLC2A10 ADRA1D LIPA SLC38A4 FSHR POU1F1 MRGPRX2 HMGCR HSD11B2 GRM8

1.18e-0610136714CID000003413
Drug3-isoreserpine

SLC6A4 ADRA1D ABCA1 ABCA2 ABCA4 ABCB6 ABCA7

1.44e-06190677CID000005052
DrugLEO275

ABCA1 ABCA2 NPC1L1 ABCB6 ABCA7

3.61e-0679675CID000018140
DrugAspartylglutamate

LHCGR FSHR GRM8 STT3B

5.78e-0640674CID000151403
DrugChoriogonadotropin alfa

LHCGR FSHR

8.53e-062672DB00097
DrugMenotropins

LHCGR FSHR

8.53e-062672DB00032
Drugsterol

ABCA1 ABCA2 LIPA ABCA4 NPC1L1 HMGCR ABCA7

1.28e-05265677CID000001107
Drugthialysine

KAT2B KAT2A PTGDR

1.61e-0517673CID000020048
DrugTriolein

ABCA1 NPC1L1 HMGCR

1.61e-0517673ctd:D014304
Drugsodium

SLC38A1 SLC6A4 GABRG1 SLC2A10 GPR89B SLC16A2 SLC38A4 ATP2C2 HMGCR HUWE1 PTGDR SLC7A11

1.76e-059446712CID000000923
Drugmono-(2-ethylhexyl)phthalate

LHCGR ADRA1D ABCA4 NPC1L1 FSHR HMGCR HSD11B2 MYO15A SLC7A11 ABCA7

2.13e-056586710ctd:C016599
Drugmyo-inositol

LHCGR KAT2B ADRA1D VNN2 RASA4 CYSLTR1 ATP2C2 FSHR GPRC5D BSCL2 GRM8

2.28e-058116711CID000000892
DrugIron oxide in water

SLC16A2 RASA4 HSD11B2

2.28e-0519673CID000518696
DrugGuanfacine hydrochloride [29110-48-3]; Up 200; 14.2uM; PC3; HT_HG-U133A

PCSK2 ABCA2 GPR75 ATP2C2 POU1F1 ITPR2

2.30e-051946764660_UP
DrugNSC3364

ABCA1 ABCA2 RASA4 NPC1L1 HMGCR

2.57e-05118675CID000025439
Drug0173570-0000 [211245-44-2]; Up 200; 1uM; PC3; HT_HG-U133A

ABCA2 GPR75 ATP2C2 PCNX1 SLC7A11 TMEM50B

2.57e-051986767391_UP
DrugEzetimibe

ABCA1 NPC1L1 HMGCR

2.68e-0520673ctd:D000069438
Drug17 alpha-hydroxy-20 beta-dihydroprogesterone

LHCGR FSHR HSD11B2

3.60e-0522673CID000107701
Drugdalcetrapib

ABCA1 HMGCR HSD11B2

4.14e-0523673CID006918540
Drugdocetaxel

ABCA1 MAL ABCA4 ABCB6 ABCA7

4.56e-05133675ctd:C067311
DrugAC1L1HK7

HSD11B2 PTGDR

5.10e-054672CID000004166
DrugCoenzyme A

KAT2B HMGCR

5.10e-054672DB01992
Drugalpha-bromoergocriptine

TPO LHCGR ADRA1D FSHR POU1F1

6.22e-05142675CID000002443
Drugezetimibe

SLC6A4 PCSK2 ABCA1 NPC1L1 HMGCR

7.33e-05147675CID000150311
DrugAC1L9NP0

SLC6A4 ADRA1D

8.48e-055672CID000449842
DrugNedocromil

CYSLTR1 PTGDR

8.48e-055672DB00716
Drugverapamil

ADRA1D ABCA1 ABCA2 ABCA4 KCNA10 ATP2C2 ABCB6 ABCA7

9.31e-05490678CID000002520
Drugepicholesterol

ABCA1 ABCA2 LIPA MAL ABCA4 NPC1L1 ATP2C2 HMGCR ABCA7

9.87e-05636679CID000000304
DrugIN1025

ABCA2 NPC1L1 HMGCR ABCA7

1.06e-0483674CID000415541
DrugZineb

TPO HSD11B2

1.27e-046672ctd:D015038
Drug17-isoprogesterone

GABRG1 LHCGR SLC2A10 ABCA2 LIPA NPC1L1 FSHR HMGCR HSD11B2 HUWE1 GRM8 SLC7A11

1.40e-0411706712CID000004920
DiseaseHMG CoA reductase inhibitor use measurement

SLC38A1 ABCA1 NPC1L1 PCNX1 HMGCR

6.19e-05189655EFO_0009932
DiseaseHypercholesterolemia

ABCA1 LIPA HMGCR

8.81e-0539653C0020443
Diseasekidney disease (implicated_via_orthology)

KAT2B KAT2A CDC42

1.02e-0441653DOID:557 (implicated_via_orthology)
Diseaseantihyperlipidemic drug use measurement

SLC38A1 ABCA1 NPC1L1 HMGCR

1.23e-04115654EFO_0803367
Diseasepremature menopause (biomarker_via_orthology)

ABCA1 HMGCR

1.33e-048652DOID:10787 (biomarker_via_orthology)
Diseasepulmonary hypertension (implicated_via_orthology)

SLC6A4 CYSLTR1 HMGCR

2.34e-0454653DOID:6432 (implicated_via_orthology)
Diseasegranulosa cell tumor (is_marker_for)

LHCGR FSHR

2.59e-0411652DOID:2999 (is_marker_for)
Diseasevery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

SLC38A1 SLC6A4 ABCA1 NPC1L1 HMGCR

2.94e-04264655EFO_0008317, EFO_0020944
Diseasepolycystic ovary syndrome

LHCGR THADA FSHR

3.19e-0460653EFO_0000660
DiseaseCongenital Hypothyroidism

TPO POU1F1

3.67e-0413652C0010308
DiseaseHyperlipoproteinemia Type IIb

ABCA1 HMGCR

3.67e-0413652C1704417
Diseaselow density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

SLC38A1 ABCA1 NPC1L1 HMGCR

3.68e-04153654EFO_0004611, EFO_0020944
Diseaseasthma (is_implicated_in)

SLC6A4 CYSLTR1 HMGCR PTGDR

4.06e-04157654DOID:2841 (is_implicated_in)
Diseasevery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

SLC38A1 SLC6A4 ABCA1 NPC1L1 HMGCR

4.59e-04291655EFO_0008317, EFO_0020946
DiseaseHyperlipoproteinemia Type IIa

ABCA1 HMGCR

5.62e-0416652C0745103
DiseaseHypercholesterolemia, Familial

ABCA1 HMGCR

7.15e-0418652C0020445
Diseasemosquito bite reaction itch intensity measurement, mosquito bite reaction size measurement

SLC6A4 ABCA1 LIPA ASB3 GRM8

7.88e-04328655EFO_0008377, EFO_0008378
Diseaseattention deficit hyperactivity disorder (is_implicated_in)

SLC6A4 GRM8

8.85e-0420652DOID:1094 (is_implicated_in)
Diseasenon-high density lipoprotein cholesterol measurement

SLC38A1 ABCA1 THADA LIPA CD163L1 NPC1L1 HMGCR

9.65e-04713657EFO_0005689
Diseasemyocardial infarction

SLC38A1 SLC6A4 THADA LIPA HMGCR

1.05e-03350655EFO_0000612
Diseasesleep duration, low density lipoprotein cholesterol measurement

SLC6A4 NPC1L1 HMGCR

1.08e-0391653EFO_0004611, EFO_0005271
Diseaselipid measurement, intermediate density lipoprotein measurement

ABCA1 NPC1L1 HMGCR

1.26e-0396653EFO_0004529, EFO_0008595
Diseasephospholipid measurement, intermediate density lipoprotein measurement

ABCA1 NPC1L1 HMGCR

1.38e-0399653EFO_0004639, EFO_0008595
Diseasesystemic mastocytosis

ABCA1 ABCA2

1.39e-0325652MONDO_0016586
Diseasetriglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement

SLC38A1 ABCA1 NPC1L1 HMGCR

1.55e-03225654EFO_0008317, EFO_0020947
Diseasefree cholesterol measurement, intermediate density lipoprotein measurement

ABCA1 NPC1L1 HMGCR

1.59e-03104653EFO_0008591, EFO_0008595
Diseasemean reticulocyte volume

KAT2B THADA ASB3 MAST1 KAT2A ALG6 ABCA7

1.85e-03799657EFO_0010701
Diseasevery low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

SLC38A1 SLC6A4 ABCA1 HMGCR

1.93e-03239654EFO_0008317, EFO_0020945
DiseaseD dimer measurement

ABCA4 GCNT1

2.00e-0330652EFO_0004507
Diseasefree cholesterol measurement

ABCA1 NPC1L1 HMGCR

2.01e-03113653EFO_0008591
Diseasetotal cholesterol measurement, low density lipoprotein cholesterol measurement

ABCA1 NPC1L1 HMGCR

2.06e-03114653EFO_0004574, EFO_0004611

Protein segments in the cluster

PeptideGeneStartEntry
VVAICVIFSMSFVPA

ABCA4

1681

P78363
VVTTMAFFIACVTSF

ALG6

391

Q9Y672
VIFAMSFVPASFVVF

ABCA1

1661

O95477
CFFFTLVPSTRMALG

ABCB6

26

Q9NP58
CPFSFAMFRFGQAVT

CD163L1

91

Q9NR16
PVATFRSCMEVNFFG

HSD11B2

181

P80365
PRTTTMTFTCFVFFD

ATP2C2

836

O75185
CVVFAMSFVPASFTL

ABCA7

1541

Q8IZY2
MGMIFFCSPIVSIFT

SLC16A2

151

P36021
VTSFLCLRFFSPAIM

RASA4

466

O43374
VSAFSLAFCALPFMG

PTGDR

156

Q13258
NLSFVDICFASTMVP

OR7A2P

66

Q8NGA2
VTSFLCLRFFSPAIM

RASA4B

466

C9J798
RMFPTQGFTEIVFCA

KAT2A

566

Q92830
VAICTSMLFFFSKPV

ITPR2

2271

Q14571
FTDFTCMAPISFFAI

LHCGR

576

P22888
RMFPSQGFTEIVFCA

KAT2B

561

Q92831
LPMFGSSFFFIQSCS

MYO15A

3411

Q9UKN7
TALLCLMVFVSAFSF

SLC2A10

411

O95528
FVFMTFFPACVSLVL

HMGCR

206

P04035
MLFIQAAVSAFFSTP

PCNX1

1486

Q96RV3
LVMACTEAFFPFISR

TPO

11

P07202
ATPAGVRFVSLSFCM

INTS2

421

Q9H0H0
DVFLVCFSVVSPSSF

CDC42

76

P60953
TFLMIAAPDTIICSF

GRM8

636

O00222
FICSVGFTSPMLFDE

HUWE1

1131

Q7Z6Z7
VTAPMFTFVLFFSSA

GPR75

96

O95800
LTFAENPFVVGMFCS

MAST1

426

Q9Y2H9
VTCFHVPYSALTMFI

MFSD2A

171

Q8NA29
FMLSLCLVPTFAVSC

NPC1L1

1141

Q9UHC9
MFTDPFFMVESTCIV

KCNA10

266

Q16322
CLVFGFSSPVCMAFQ

ASB3

311

Q9Y575
TLLCVSFPFAQFSKM

DNASE2

156

O00115
TAMDLFVSVCFIFVF

GABRG1

331

Q8N1C3
QVIFSVTFAFSCTMF

GPR89A

41

B7ZAQ6
VTFAFSCTMFELIIF

GPR89A

46

B7ZAQ6
QVIFSVTFAFSCTMF

GPR89B

41

P0CG08
VTFAFSCTMFELIIF

GPR89B

46

P0CG08
MALTFFVSKATFCGP

GPRC5D

181

Q9NZD1
FFVCVAMTVALSVPE

ABCA2

1466

Q9BZC7
AMSFVPASFVVFLVA

ABCA2

1801

Q9BZC7
MFVSVFCFVATTTLI

MAL

56

P21145
DFLCMAPISFFAISA

FSHR

581

P23945
VMGIASCFSNVFVAS

GCNT1

166

Q02742
PMTCAFIGVASNFTF

BSCL2

231

Q96G97
TFFEVVCNMIPFCTI

SLC15A5

56

A6NIM6
TMTHTIFTFCLPFCG

OR5G3

156

P0C626
PISLAGCATQMFFFV

OR10J5

91

Q8NHC4
VAMVCTFFDAFNVPV

RER1

131

O15258
VFTACMTLTASPGVF

TMEM248

181

Q9NWD8
FMSSICNSLFEALFP

THADA

731

Q6YHU6
ALVDCTSSVTFLPFM

SLC52A3

116

Q9NQ40
FMPLFFVSPVSVAAC

TMEM185A

116

Q8NFB2
FMPLFFVSPVSVAAC

TMEM185B

116

Q9H7F4
MSCQAFTSADTFIPL

POU1F1

1

P28069
SGFSLTCMVFFVSVV

SLC38A4

226

Q969I6
FPSFFTTVMTCAYLA

MRGPRX2

101

Q96LB1
FIFMTVVYFGPLTCS

SLC35B1

256

P78383
VFSSVCSFYLPMAVI

ADRA1D

256

P25100
TSFVVFSLFLICAMA

CLECL1

66

Q8IZS7
AMSFFRCIAIVFPVQ

CYSLTR1

116

Q9Y271
MVTSSFPISVAVFAL

VNN2

1

O95498
FIPALFSFTCLFMVA

SLC7A11

426

Q9UPY5
DALSMCFLFSTFPRT

PES1

136

O00541
PVVCMLSAIAFSNVF

STT3B

466

Q8TCJ2
FCSALPAVTEMALFV

TMEM107

116

Q6UX40
CGVFSTLAFFMINAV

TMEM50B

61

P56557
VVNCMTSFVSGFVIF

SLC6A4

366

P31645
FVTALMFSSIVCSVP

TTYH3

396

Q9C0H2
VPAFFTESSEYSCVM

ZMYND15

636

Q9H091
TSGFSLSCMVFFLIV

SLC38A1

221

Q9H2H9
MFFALGPVASVAFCT

LIPA

196

P38571
LFCVMVFASAERPVF

PCSK2

16

P16519