Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionphosphotyrosine residue binding

SHD SHE SHF

5.45e-075173GO:0001784
GeneOntologyMolecularFunctionprotein phosphorylated amino acid binding

SHD SHE SHF

1.37e-066973GO:0045309
GeneOntologyMolecularFunctionphosphoprotein binding

SHD SHE SHF

6.75e-0611773GO:0051219
DomainXAP5

FAM50B FAM50A

8.60e-08262IPR007005
DomainXAP5

FAM50B FAM50A

8.60e-08262PF04921
DomainSH2

SHD SHE

4.28e-0410162PF00017
DomainSH2

SHD SHE

5.08e-0411062SM00252
DomainSH2

SHD SHE

5.17e-0411162PS50001
DomainSH2

SHD SHE

5.26e-0411262IPR000980
Domain-

SHD SHE

5.26e-04112623.30.505.10
Pubmed

Human and mouse XAP-5 and XAP-5-like (X5L) genes: identification of an ancient functional retroposon differentially expressed in testis.

FAM50B FAM50A

3.47e-0827210534398
Pubmed

Identification and characterization of two novel SH2 domain-containing proteins from a yeast two hybrid screen with the ABL tyrosine kinase.

SHD SHE

9.72e-078729315092
Pubmed

Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome.

SHD SHE

9.06e-05737224728074
Pubmed

Comprehensive binary interaction mapping of SH2 domains via fluorescence polarization reveals novel functional diversification of ErbB receptors.

SHD SHE

1.01e-04777222973453
GeneFamilySH2 domain containing

SHD SHE SHF

6.74e-0710143741
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_dendritic-plasmacytoid_dendritic_cell|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FAM50B SHD

1.91e-04137723f4746fb6fc36c90a8cd25725531a1503422cfbf
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-MyoFB-3|PND07-28-samps / Age Group, Lineage, Cell class and subclass

SHD CLINT1

2.03e-04141727ae8ead02e5aeb4106c4a30c08a7a061da3a5d6a
ToppCell10x5'-bone_marrow-Myeloid_Dendritic-DC1|bone_marrow / Manually curated celltypes from each tissue

SLC15A1 SHE

2.64e-04161722f068ee643de2f647c289779a6624265ab9a749b
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SHD SHF

2.64e-0416172bd520c9a1927d5d5355b4421e6b90b58bfb76a42
ToppCell10x5'v1-week_12-13-Myeloid_neutrophil-granulo-eo/baso/mast-eosinophil|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SHD CLINT1

2.91e-0416972f68195510b91e287fe1507455ca067ece77a3897
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.4|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLINT1 SHF

3.05e-0417372176b956e71d98e8275d698b39437fc326e5fe449
ToppCell(0)_Myeloid-(011)_pDC|(0)_Myeloid / immune cells in Peripheral Blood (logTPM normalization)

SHD SHF

3.60e-0418872a81b5d840490d6a636fe168f8cff2c4984369f09
ToppCellLPS-IL1RA-Endothelial-Endothelial-Vein|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHE SHF

3.75e-0419272717f3d3bbee4d0f64ba1341ee2b00a407ba1e0f3
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHD SHE

3.75e-04192724fc98f30f8e738816cd93101fbe8ac40889e302a
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHD SHE

3.75e-0419272be75783d9578974b662e1cb13bd3442a921fd50a
DrugAC1O4QO4

SLC15A1 FAM50A

4.26e-053372CID000002654
Drugurapidil

FAM50A SHE

4.52e-053472CID000005639
DrugSonoVue

SHD SHE

4.80e-053572CID000017358
DrugTops

FAM50A SHF

5.67e-053872CID000169814
DrugSecorvas

SLC15A1 SHE

6.94e-054272CID000003419
DrugM NA

SHE SHF

7.27e-054372CID000007423
DrugAC-474

SHD CLINT1

1.37e-045972CID000002999
Drug8-anilino-1-naphthalenesulfonate

CLINT1 SHF

2.28e-047672CID000001369
DrugArg-pro

SLC15A1 CLINT1

2.66e-048272CID000151003
Drugbromovanin

FAM50B FAM50A

6.37e-0412772ctd:C515564
DrugHydrocotarnine hydrobromide [5985-00-2]; Down 200; 13.2uM; MCF7; HT_HG-U133A

FAM50B CLINT1

1.52e-03197722765_DN
DrugCP-944629 [668990-94-1]; Up 200; 10uM; MCF7; HT_HG-U133A

FAM50B SLC15A1

1.54e-03198727497_UP
DrugSC 19220; Up 200; 10uM; PC3; HT_HG-U133A

FAM50B CLINT1

1.54e-03198727095_UP
DrugSuramin sodium salt; Up 200; 10uM; MCF7; HT_HG-U133A

FAM50B SLC15A1

1.55e-03199727496_UP
DrugPropylthiouracil [51-52-5]; Up 200; 23.4uM; HL60; HT_HG-U133A

FAM50B SLC15A1

1.55e-03199722476_UP
DrugAC1L1IZ2

SHD SHF

3.57e-0330472CID000004795

Protein segments in the cluster

PeptideGeneStartEntry
YDPEPKSKWDEEWDK

CLINT1

176

Q14677
ASRWEPYDPEKKWDK

FAM50A

321

Q14320
PKREHWLDWAKEKYD

SLC15A1

256

P46059
RPADEYDQPWEWKKD

SHD

176

Q96IW2
RPPEEYDQPWEWKKE

SHF

196

Q7M4L6
PAAEYEQPWEWKKEQ

SHE

321

Q5VZ18
PASRWEAYDPEKKWD

FAM50B

306

Q9Y247