Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	modification-dependent protein binding	ANKRD13D MSH6 GLYR1 UHRF1 KMT2A MLLT1 CXXC1	1.34e-05	206	76	7	GO:0140030
GeneOntologyMolecularFunction	methylated histone binding	MSH6 GLYR1 UHRF1 CXXC1	3.25e-04	86	76	4	GO:0035064
GeneOntologyMolecularFunction	methylation-dependent protein binding	MSH6 GLYR1 UHRF1 CXXC1	3.55e-04	88	76	4	GO:0140034
GeneOntologyMolecularFunction	7SK snRNA binding	CCNT2 LARP7	5.06e-04	9	76	2	GO:0097322
GeneOntologyMolecularFunction	histone binding	MSH6 GLYR1 UHRF1 KMT2A MLLT1 CXXC1	5.19e-04	265	76	6	GO:0042393
GeneOntologyMolecularFunction	unmethylated CpG binding	KMT2A CXXC1	6.31e-04	10	76	2	GO:0045322
GeneOntologyMolecularFunction	RNA polymerase III general transcription initiation factor activity	GTF3C1 SNAPC4	1.09e-03	13	76	2	GO:0000995
GeneOntologyBiologicalProcess	RNA splicing	FRA10AC1 SRSF4 PNN PRPF3 CDK13 CLK3 RBM15B ACIN1 PRPF38B ILDR1 RP9 PRPF40A THRAP3 LARP7	4.41e-09	502	77	14	GO:0008380
GeneOntologyBiologicalProcess	mRNA splicing, via spliceosome	FRA10AC1 SRSF4 PNN PRPF3 CDK13 RBM15B ACIN1 PRPF40A THRAP3 LARP7	8.55e-07	358	77	10	GO:0000398
GeneOntologyBiologicalProcess	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	FRA10AC1 SRSF4 PNN PRPF3 CDK13 RBM15B ACIN1 PRPF40A THRAP3 LARP7	8.55e-07	358	77	10	GO:0000377
GeneOntologyBiologicalProcess	RNA splicing, via transesterification reactions	FRA10AC1 SRSF4 PNN PRPF3 CDK13 RBM15B ACIN1 PRPF40A THRAP3 LARP7	9.46e-07	362	77	10	GO:0000375
GeneOntologyBiologicalProcess	mRNA processing	FRA10AC1 SRSF4 PNN PRPF3 CDK13 RBM15B ACIN1 PRPF38B PRPF40A THRAP3 LARP7	6.07e-06	551	77	11	GO:0006397
GeneOntologyBiologicalProcess	regulation of RNA splicing	SRSF4 CLK3 RBM15B ACIN1 ILDR1 THRAP3 LARP7	1.23e-05	207	77	7	GO:0043484
GeneOntologyBiologicalProcess	regulation of mRNA splicing, via spliceosome	SRSF4 RBM15B ACIN1 THRAP3 LARP7	1.22e-04	129	77	5	GO:0048024
GeneOntologyBiologicalProcess	positive regulation of insulin receptor signaling pathway	OSBPL8 PRKCZ OPA1	2.30e-04	32	77	3	GO:0046628
GeneOntologyCellularComponent	nuclear speck	SRSF4 PNN PRPF3 RBBP6 CDK13 CLK3 RBM15B ACIN1 RP9 CMYA5 CXXC1 PRPF40A THRAP3	4.78e-09	431	76	13	GO:0016607
GeneOntologyCellularComponent	nuclear body	SRSF4 TCF20 PNN SLF2 PRPF3 RBBP6 CDK13 CLK3 RBM15B ACIN1 RP9 CMYA5 SKIL CXXC1 PRPF40A THRAP3	1.22e-07	903	76	16	GO:0016604
GeneOntologyCellularComponent	nuclear protein-containing complex	CCNT2 MSH6 PNN PRPF3 CDK13 DBF4B TERB1 KMT2A ACIN1 MLLT1 PRPF38B BOD1L1 BICRAL BCOR CXXC1 PRPF40A JMJD1C THRAP3 LARP7	3.28e-07	1377	76	19	GO:0140513
GeneOntologyCellularComponent	exon-exon junction complex	PNN ACIN1 THRAP3	5.86e-05	21	76	3	GO:0035145
GeneOntologyCellularComponent	transferase complex	CCNT2 SLF2 CDK13 DBF4B TBC1D5 RBM15B KMT2A BOD1L1 PRKCZ REV3L BCOR CXXC1	1.74e-04	963	76	12	GO:1990234
GeneOntologyCellularComponent	serine/threonine protein kinase complex	CCNT2 CDK13 DBF4B TBC1D5 PRKCZ	2.70e-04	157	76	5	GO:1902554
GeneOntologyCellularComponent	protein kinase complex	CCNT2 CDK13 DBF4B TBC1D5 PRKCZ	3.89e-04	170	76	5	GO:1902911
GeneOntologyCellularComponent	cyclin/CDK positive transcription elongation factor complex	CCNT2 CDK13	4.62e-04	9	76	2	GO:0008024
GeneOntologyCellularComponent	methyltransferase complex	RBM15B KMT2A BOD1L1 CXXC1	6.50e-04	108	76	4	GO:0034708
GeneOntologyCellularComponent	transcription elongation factor complex	CCNT2 CDK13 MLLT1	1.11e-03	56	76	3	GO:0008023
GeneOntologyCellularComponent	transferase complex, transferring phosphorus-containing groups	CCNT2 CDK13 DBF4B TBC1D5 PRKCZ REV3L	1.38e-03	335	76	6	GO:0061695
GeneOntologyCellularComponent	Set1C/COMPASS complex	BOD1L1 CXXC1	1.51e-03	16	76	2	GO:0048188
GeneOntologyCellularComponent	nuclear matrix	UHRF1 PRKCZ CXXC1 PRPF40A	1.70e-03	140	76	4	GO:0016363
GeneOntologyCellularComponent	nuclear cyclin-dependent protein kinase holoenzyme complex	CCNT2 CDK13	1.92e-03	18	76	2	GO:0019908
GeneOntologyCellularComponent	histone methyltransferase complex	KMT2A BOD1L1 CXXC1	2.58e-03	75	76	3	GO:0035097
Domain	PHD	TCF20 NSD2 UHRF1 KMT2A CXXC1	3.31e-05	89	77	5	SM00249
Domain	Znf_PHD	TCF20 NSD2 UHRF1 KMT2A CXXC1	3.68e-05	91	77	5	IPR001965
Domain	ZF_PHD_2	TCF20 NSD2 UHRF1 KMT2A CXXC1	4.53e-05	95	77	5	PS50016
Domain	ZF_PHD_1	TCF20 NSD2 UHRF1 KMT2A CXXC1	4.76e-05	96	77	5	PS01359
Domain	PWWP	MSH6 NSD2 GLYR1	7.30e-05	20	77	3	SM00293
Domain	PWWP	MSH6 NSD2 GLYR1	1.12e-04	23	77	3	PF00855
Domain	PWWP_dom	MSH6 NSD2 GLYR1	1.12e-04	23	77	3	IPR000313
Domain	PWWP	MSH6 NSD2 GLYR1	1.28e-04	24	77	3	PS50812
Domain	AT_hook	GLYR1 KMT2A BOD1L1	1.84e-04	27	77	3	SM00384
Domain	AT_hook_DNA-bd_motif	GLYR1 KMT2A BOD1L1	1.84e-04	27	77	3	IPR017956
Domain	PHD	NSD2 UHRF1 KMT2A CXXC1	2.60e-04	75	77	4	PF00628
Domain	Znf_PHD-finger	NSD2 UHRF1 KMT2A CXXC1	3.17e-04	79	77	4	IPR019787
Domain	Znf_FYVE_PHD	TCF20 NSD2 UHRF1 KMT2A CXXC1	3.53e-04	147	77	5	IPR011011
Domain	Znf_CXXC	KMT2A CXXC1	9.01e-04	11	77	2	IPR002857
Domain	ZF_CXXC	KMT2A CXXC1	9.01e-04	11	77	2	PS51058
Domain	zf-CXXC	KMT2A CXXC1	9.01e-04	11	77	2	PF02008
Domain	ZnF_C2HC	RBBP6 ZCCHC17 RP9	1.52e-03	55	77	3	SM00343
Domain	Znf_CCHC	RBBP6 ZCCHC17 RP9	1.52e-03	55	77	3	IPR001878
Domain	Post-SET_dom	NSD2 KMT2A	1.94e-03	16	77	2	IPR003616
Domain	PostSET	NSD2 KMT2A	1.94e-03	16	77	2	SM00508
Domain	POST_SET	NSD2 KMT2A	1.94e-03	16	77	2	PS50868
Domain	RRM	SRSF4 U2SURP RBM15B ACIN1 LARP7	2.03e-03	217	77	5	SM00360
Domain	RRM_dom	SRSF4 U2SURP RBM15B ACIN1 LARP7	2.46e-03	227	77	5	IPR000504
Domain	-	SRSF4 U2SURP RBM15B ACIN1 LARP7	3.36e-03	244	77	5	3.30.70.330
Domain	EPHD	TCF20 KMT2A	3.67e-03	22	77	2	PS51805
Domain	Nucleotide-bd_a/b_plait	SRSF4 U2SURP RBM15B ACIN1 LARP7	4.26e-03	258	77	5	IPR012677
Domain	-	RBBP6 ZCCHC17	5.11e-03	26	77	2	4.10.60.10
Pathway	KEGG_MEDICUS_VARIANT_MLL_AF4_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION	CCNT2 KMT2A MLLT1 JMJD1C	2.14e-06	26	51	4	M47439
Pathway	KEGG_SPLICEOSOME	SRSF4 PRPF3 U2SURP ACIN1 PRPF38B PRPF40A	6.14e-06	127	51	6	M2044
Pathway	WP_MRNA_PROCESSING	SRSF4 PRPF3 CLK3 U2SURP RBM15B ACIN1 ZNF740 RSRC2 PRPF40A	2.99e-05	451	51	9	MM15946
Pathway	REACTOME_MRNA_SPLICING	SRSF4 PNN PRPF3 U2SURP ACIN1 PRPF40A	1.10e-04	212	51	6	M14033
Pathway	REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX	CCNT2 PRKCZ SKIL PPM1A	1.69e-04	77	51	4	MM14670
Pathway	REACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES	KMT2A BOD1L1 CXXC1	3.44e-04	38	51	3	MM17073
Pathway	REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX	CCNT2 PRKCZ SKIL PPM1A	3.65e-04	94	51	4	M1041
Pathway	REACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER	CCNT2 SKIL PPM1A	4.32e-04	41	51	3	MM14876
Pathway	REACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES	KMT2A BOD1L1 CXXC1	4.64e-04	42	51	3	M48018
Pathway	REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA	SRSF4 PNN PRPF3 U2SURP ACIN1 PRPF40A	5.24e-04	283	51	6	M13087
Pathway	REACTOME_MRNA_SPLICING	PNN PRPF3 U2SURP ACIN1 PRPF40A	7.73e-04	201	51	5	MM15411
Pathway	REACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER	CCNT2 SKIL PPM1A	8.22e-04	51	51	3	M665
Pathway	REACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS	CCNT2 PRKCZ SKIL PPM1A	8.61e-04	118	51	4	MM15588
Pathway	REACTOME_GENE_EXPRESSION_TRANSCRIPTION	CCNT2 GTF3C1 CDK13 KMT2A MLLT1 ZNF740 BOD1L1 SNAPC4 SKIL CXXC1 PPM1A	8.89e-04	1022	51	11	MM15436
Pathway	KEGG_MEDICUS_VARIANT_MLL_ENL_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION	KMT2A MLLT1	9.76e-04	13	51	2	M47440
Pathway	WP_MRNA_PROCESSING	SRSF4 PRPF3 CLK3 PRPF40A	1.10e-03	126	51	4	M39406
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	CEP170 CCNT2 MSH6 SRSF4 TCF20 GTF3C1 PNN PRPF3 RBBP6 NSD2 CLK3 GLYR1 U2SURP NEMF RBM15B ACIN1 PRPF38B ZCCHC17 RSRC2 CXXC1 PRPF40A THRAP3 OPA1 UNC13A	5.99e-18	1082	77	24	38697112
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	SRSF4 TCF20 GTF3C1 PNN SLF2 PRPF3 RBBP6 NSD2 CDK13 GLYR1 U2SURP RBM15B UHRF1 KMT2A ACIN1 MLLT1 ZNF740 AATF BCOR SKIL CXXC1 PRPF40A TOR1AIP1 JMJD1C THRAP3	2.67e-17	1294	77	25	30804502
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	CEP170 SRSF4 TCF20 PNN SLF2 PRPF3 RBBP6 NSD2 U2SURP RBM15B KMT2A ACIN1 MLLT1 AATF BOD1L1 RP9 BCOR PRPF40A TOR1AIP1 JMJD1C THRAP3	1.20e-15	954	77	21	36373674
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	SRSF4 MAP1S PRPF3 RBBP6 CLK3 RBM15B UHRF1 KMT2A ACIN1 PRPF38B BOD1L1 CXXC1 THRAP3	1.29e-14	251	77	13	31076518
Pubmed	RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.	CEP170 CCNT2 MSH6 SRSF4 GTF3C1 PNN PRPF3 RBBP6 CLK3 U2SURP RBM15B ACIN1 PRPF38B RSRC2 PRPF40A THRAP3 LARP7	2.58e-13	713	77	17	29802200
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	CEP170 MSH6 GTF3C1 PNN PRPF3 RBBP6 NSD2 CDK13 GLYR1 NEMF RBM15B UHRF1 ACIN1 AATF ZCCHC17 ZBTB11 LARP7	7.01e-13	759	77	17	35915203
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	CEP170 MSH6 SRSF4 TCF20 GTF3C1 PNN NSD2 GLYR1 U2SURP OSBPL8 KMT2A ACIN1 AATF ZBTB11 PRPF40A LARP7	9.42e-13	653	77	16	22586326
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	CCNT2 MSH6 TCF20 GTF3C1 MAP1S PNN RBBP6 CDK13 RBM15B KMT2A ACIN1 PRPF38B SNAPC4 BCOR PRPF40A THRAP3 ANKS1A	9.57e-13	774	77	17	15302935
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	TNIK CEP170 MSH6 PNN PRPF3 RBBP6 TBC1D5 U2SURP CASP3 KMT2A ACIN1 PRPF38B BOD1L1 BCOR CAMSAP1 PRPF40A TOR1AIP1 ANKS1A	1.66e-12	934	77	18	33916271
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	SRSF4 PNN PRPF3 RBBP6 CDK13 CLK3 U2SURP RBM15B ACIN1 AATF ZCCHC17 RP9 RSRC2 PRPF40A THRAP3 LARP7	2.23e-11	807	77	16	22681889
Pubmed	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	CEP170 SRSF4 TCF20 PNN PRPF3 RBBP6 UHRF1 ACIN1 PRPF40A THRAP3 LARP7	2.50e-11	274	77	11	34244482
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	CEP170 MAP1S PNN RBBP6 CDK13 RBM15B PRPF38B ZCCHC17 MYO18B CAMSAP1 JMJD1C THRAP3	2.62e-11	361	77	12	26167880
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	CCNT2 MSH6 TCF20 GTF3C1 PNN PRPF3 RBBP6 NSD2 CDK13 UHRF1 KMT2A ACIN1 PRPF38B BOD1L1 PRPF40A THRAP3 LARP7	6.60e-11	1014	77	17	32416067
Pubmed	Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.	CEP170 PNN NSD2 GLYR1 NEMF OSBPL8 ACIN1 AATF PRPF40A TOR1AIP1 LARP7	1.94e-10	332	77	11	25693804
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	CEP170 MSH6 TCF20 GTF3C1 PNN RBBP6 KMT2A ACIN1 BOD1L1 BCOR PRPF40A JMJD1C THRAP3	2.40e-10	549	77	13	38280479
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	SRSF4 GTF3C1 PNN PRPF3 RBBP6 GLYR1 U2SURP RBM15B KMT2A ACIN1 AATF PRPF40A TOR1AIP1 THRAP3 LARP7	4.82e-10	847	77	15	35850772
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CEP170 NHSL1 STOX2 TCF20 SLF2 CLK3 TBC1D5 OSBPL8 KMT2A BOD1L1 CAMSAP1 TMCC3 PPM1A FAM83B ANKS1A	6.04e-10	861	77	15	36931259
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	TNIK CEP170 CDK13 GLYR1 PEG3 NEMF RBM15B OSBPL8 UHRF1 KMT2A ACIN1 AATF PRPF38B ZCCHC17 RSRC2 PRPF40A THRAP3 LARP7	8.50e-10	1371	77	18	36244648
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	MSH6 GTF3C1 PNN NSD2 GLYR1 U2SURP NEMF RBM15B UHRF1 ACIN1 BOD1L1 MYO18B CMYA5 PRPF40A TOR1AIP1 THRAP3 OPA1 LARP7	1.56e-09	1425	77	18	30948266
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	MSH6 GTF3C1 PNN RBBP6 CDK13 U2SURP ACIN1 RP9 ZBTB11 PRPF40A THRAP3 OPA1 FAM83B	2.03e-09	655	77	13	35819319
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	CEP170 MSH6 PRPF3 RBBP6 NSD2 MLLT1 ZNF740 BICRAL REV3L RSRC2 BCOR RALGAPA2 SKIL PRPF40A OPA1 LARP7	2.47e-09	1116	77	16	31753913
Pubmed	The protein interaction landscape of the human CMGC kinase group.	CCNT2 SRSF4 PNN RBBP6 CDK13 CLK3 DBF4B ACIN1 MLLT1 RSRC2 PRPF40A THRAP3 LARP7	4.12e-09	695	77	13	23602568
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	MSH6 PNN PRPF3 GLYR1 U2SURP RBM15B KMT2A ACIN1 AATF PRPF40A THRAP3 LARP7	9.05e-09	605	77	12	28977666
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	MSH6 TCF20 GTF3C1 NSD2 GLYR1 UHRF1 KMT2A BOD1L1 SNAPC4 BCOR ZBTB11 JMJD1C	9.56e-09	608	77	12	36089195
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	CCNT2 SRSF4 PNN RBBP6 U2SURP NEMF ACIN1 MLLT1 PRPF38B PRKCZ RSRC2 PRPF40A THRAP3 OPA1 LARP7 FAM83B	1.18e-08	1247	77	16	27684187
Pubmed	In vitro nuclear interactome of the HIV-1 Tat protein.	PNN RBBP6 NSD2 KMT2A ACIN1 AATF CXXC1 TOR1AIP1	1.28e-08	195	77	8	19454010
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	MSH6 TCF20 PRPF3 RBBP6 GLYR1 ACIN1 BOD1L1 JMJD1C THRAP3	1.37e-08	283	77	9	30585729
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	CEP170 CCNT2 MSH6 TCF20 GTF3C1 PRPF3 CDK13 U2SURP KMT2A PRPF38B BICRAL RSRC2 BCOR JMJD1C THRAP3	1.69e-08	1103	77	15	34189442
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	CEP170 GTF3C1 PRPF3 NSD2 CDK13 GLYR1 TBC1D5 MYT1 NEMF PRPF38B BOD1L1 PRKCZ KATNAL1 PNPLA7 JMJD1C THRAP3 ANKS1A	2.14e-08	1489	77	17	28611215
Pubmed	MLL-AF9 and MLL-ENL alter the dynamic association of transcriptional regulators with genes critical for leukemia.	CCNT2 KMT2A MLLT1 BCOR	2.19e-08	14	77	4	20854876
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	MSH6 SRSF4 PNN RBBP6 U2SURP OSBPL8 KMT2A ACIN1 AATF PRPF38B ZCCHC17 RP9 PRPF40A THRAP3 OPA1 LARP7	2.56e-08	1318	77	16	30463901
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	CCNT2 MSH6 GTF3C1 PNN NSD2 UHRF1 KMT2A ACIN1 AATF ZBTB11 PRPF40A	2.65e-08	533	77	11	30554943
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	TNIK GTF3C1 PNN RBBP6 U2SURP RBM15B BOD1L1 PRPF40A THRAP3	3.26e-08	313	77	9	38270169
Pubmed	ZBTB2 protein is a new partner of the Nucleosome Remodeling and Deacetylase (NuRD) complex.	MSH6 SRSF4 TCF20 PNN NSD2 GLYR1 ACIN1 PRPF40A THRAP3	5.12e-08	330	77	9	33301849
Pubmed	Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.	SRSF4 PNN PRPF3 RBBP6 CLK3 U2SURP RBM15B ACIN1 PRPF38B RSRC2 PRPF40A THRAP3	7.17e-08	731	77	12	29298432
Pubmed	Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.	MSH6 SRSF4 GTF3C1 PNN U2SURP ACIN1 THRAP3 LARP7	7.26e-08	244	77	8	29884807
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	FRA10AC1 GTF3C1 PNN NSD2 CDK13 U2SURP SCN9A KMT2A ACIN1 MLLT1 AATF BOD1L1 ZBTB11 CXXC1 THRAP3 LARP7	8.80e-08	1442	77	16	35575683
Pubmed	Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.	CEP170 PNN CLK3 ACIN1 PRPF38B PRPF40A THRAP3 ANKS1A	1.02e-07	255	77	8	15324660
Pubmed	PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.	MSH6 SRSF4 PNN U2SURP TERB1 ACIN1 PRPF40A THRAP3 OPA1 LARP7	1.04e-07	477	77	10	31300519
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	MSH6 LOXHD1 SRSF4 PNN PRPF3 CLK3 ACIN1 PRPF38B CMYA5 PRPF40A JMJD1C THRAP3 OPA1 PPM1A ANKS1A	1.22e-07	1284	77	15	17353931
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	STOX2 TCF20 PNN CAMSAP1 TOR1AIP1 JMJD1C FAM83B ANKS1A	1.29e-07	263	77	8	34702444
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	MSH6 RBBP6 NSD2 CDK13 CLK3 RBM15B OSBPL8 KMT2A MLLT1 AATF PRPF38B RSRC2 BCOR ZBTB11 LARP7 FAM83B	1.46e-07	1497	77	16	31527615
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	TCF20 PNN PRPF3 U2SURP KMT2A BCOR SKIL JMJD1C	1.49e-07	268	77	8	33640491
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	PNN PRPF3 RBBP6 CDK13 CLK3 GLYR1 U2SURP UHRF1 AATF ZCCHC17 RP9 PRPF40A THRAP3	1.57e-07	949	77	13	36574265
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	MSH6 PRPF3 RBBP6 CDK13 U2SURP ACIN1 BOD1L1 PRPF40A THRAP3 LARP7	1.78e-07	506	77	10	30890647
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	CEP170 RBBP6 U2SURP SCN9A BCOR CAMSAP1 JMJD1C	1.82e-07	184	77	7	32908313
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	MSH6 TCF20 GLYR1 MYT1 PEG3 UHRF1 ACIN1 ZNF740 AATF SNAPC4 SKIL CXXC1	2.10e-07	808	77	12	20412781
Pubmed	Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes.	SRSF4 PNN PRPF3 U2SURP ACIN1 PRPF40A	2.24e-07	115	77	6	17332742
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	MSH6 TCF20 GTF3C1 GLYR1 U2SURP UHRF1 ACIN1 AATF BOD1L1 ZBTB11 PRPF40A JMJD1C THRAP3	2.51e-07	989	77	13	36424410
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	CCNT2 CDK13 CLK3 RBM15B REV3L THRAP3 LARP7	2.89e-07	197	77	7	20811636
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	SRSF4 GTF3C1 PNN PRPF3 CDK13 UHRF1 ACIN1 CXXC1 OPA1	3.20e-07	410	77	9	26949251
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	CEP170 TCF20 GTF3C1 PNN PRPF3 U2SURP UHRF1 ACIN1 AATF PRPF40A TOR1AIP1 THRAP3 FAM83B	3.72e-07	1024	77	13	24711643
Pubmed	KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.	PRPF3 U2SURP ACIN1 RSRC2 PRPF40A THRAP3	4.63e-07	130	77	6	35545047
Pubmed	Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS.	CCNT2 STOX2 MAP1S PNN KMT2A MLLT1 THRAP3 LARP7 FAM83B	4.96e-07	432	77	9	23455922
Pubmed	TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.	TCF20 PRPF3 U2SURP ACIN1 BCOR PRPF40A THRAP3	6.08e-07	220	77	7	35785414
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	TNIK CEP170 TCF20 OSBPL8 CASP3 BOD1L1 RSRC2 CAMSAP1 TOR1AIP1 JMJD1C ANKS1A	6.39e-07	733	77	11	34672954
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	MSH6 TCF20 SLF2 PRPF3 MLLT1 AATF REV3L	6.46e-07	222	77	7	37071664
Pubmed	HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137.	CCNT2 PNN PRPF3 ACIN1 JMJD1C THRAP3	9.91e-07	148	77	6	32538781
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	SEMA6D PNN RBBP6 CLK3 CASP3 ACIN1 THRAP3 OPA1	1.32e-06	358	77	8	32460013
Pubmed	TRIM65 regulates microRNA activity by ubiquitination of TNRC6.	CEP170 PRPF3 U2SURP NEMF AATF ZBTB11 THRAP3 LARP7	1.50e-06	364	77	8	24778252
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	MSH6 RBBP6 GLYR1 NEMF RBM15B PRPF38B MYO18B CXXC1 LARP7	1.55e-06	496	77	9	31343991
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	CEP170 NSD2 GLYR1 UHRF1 KMT2A RSRC2 CAMSAP1 TOR1AIP1 THRAP3 LARP7	1.61e-06	645	77	10	25281560
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	MSH6 GTF3C1 PNN RBBP6 CDK13 UHRF1 ACIN1 ZNF740 THRAP3	1.74e-06	503	77	9	16964243
Pubmed	A bead-based approach for large-scale identification of in vitro kinase substrates.	MSH6 PNN ACIN1 PRPF40A THRAP3 LARP7	1.74e-06	163	77	6	22113938
Pubmed	SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response.	SRSF4 PNN CDK13 ACIN1 AATF THRAP3 TMCC3	1.81e-06	259	77	7	30404004
Pubmed	Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.	PNN RBBP6 CDK13 U2SURP ACIN1 RP9 BCOR PRPF40A JMJD1C THRAP3	2.12e-06	665	77	10	30457570
Pubmed	Insights into the ubiquitin-proteasome system of human embryonic stem cells.	CEP170 SRSF4 GLYR1 U2SURP PRPF38B ZCCHC17 PRPF40A	2.32e-06	269	77	7	29511261
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	TCF20 GTF3C1 PRPF3 GLYR1 U2SURP UHRF1 KMT2A AATF	2.69e-06	394	77	8	27248496
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	CEP170 PNN RBBP6 ACIN1 BOD1L1 BCOR PRPF40A THRAP3	2.95e-06	399	77	8	35987950
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	TCF20 PNN RBBP6 KMT2A ACIN1	3.45e-06	103	77	5	32744500
Pubmed	The E3 ubiquitin ligase UBR5 interacts with the H/ACA ribonucleoprotein complex and regulates ribosomal RNA biogenesis in embryonic stem cells.	SRSF4 U2SURP PRPF38B ZCCHC17 PRPF40A	3.61e-06	104	77	5	31365120
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	CEP170 MSH6 GTF3C1 PNN PRPF3 RBBP6 CLK3 GLYR1 RBM15B ACIN1 AATF THRAP3 FAM83B	3.62e-06	1257	77	13	36526897
Pubmed	Transcription factor protein interactomes reveal genetic determinants in heart disease.	MSH6 GTF3C1 GLYR1 OSBPL8 UHRF1 KMT2A PRPF40A THRAP3	3.67e-06	411	77	8	35182466
Pubmed	PIP30/FAM192A is a novel regulator of the nuclear proteasome activator PA28γ.	ZCCHC17 RP9 PRPF40A THRAP3	3.68e-06	47	77	4	29934401
Pubmed	A PWWP Domain of Histone-Lysine N-Methyltransferase NSD2 Binds to Dimethylated Lys-36 of Histone H3 and Regulates NSD2 Function at Chromatin.	MSH6 NSD2 GLYR1	3.73e-06	14	77	3	26912663
Pubmed	Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.	SRSF4 PNN RBBP6 CDK13 CLK3 PRPF38B ZCCHC17 PRPF40A THRAP3 LARP7	4.43e-06	723	77	10	34133714
Pubmed	Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival.	RBM15B KMT2A BOD1L1 CXXC1	4.73e-06	50	77	4	37974198
Pubmed	Association of PAP-1 and Prp3p, the products of causative genes of dominant retinitis pigmentosa, in the tri-snRNP complex.	PRPF3 RP9	4.84e-06	2	77	2	15541726
Pubmed	The ENL YEATS epigenetic reader domain critically links MLL-ENL to leukemic stem cell frequency in t(11;19) Leukemia.	KMT2A MLLT1	4.84e-06	2	77	2	36435883
Pubmed	Spliced MLL fusions: a novel mechanism to generate functional chimeric MLL-MLLT1 transcripts in t(11;19)(q23;p13.3) leukemia.	KMT2A MLLT1	4.84e-06	2	77	2	17252016
Pubmed	Molecular characterization of a novel nucleolar protein, pNO40.	PNN ZCCHC17	4.84e-06	2	77	2	12893261
Pubmed	Clinical outcome and monitoring of minimal residual disease in patients with acute lymphoblastic leukemia expressing the MLL/ENL fusion gene.	KMT2A MLLT1	4.84e-06	2	77	2	21953510
Pubmed	Two distinct portions of LTG19/ENL at 19p13 are involved in t(11;19) leukemia.	KMT2A MLLT1	4.84e-06	2	77	2	8378076
Pubmed	Acute myeloid leukemia induced by MLL-ENL is cured by oncogene ablation despite acquisition of complex genetic abnormalities.	KMT2A MLLT1	4.84e-06	2	77	2	19029444
Pubmed	Acinus is a caspase-3-activated protein required for apoptotic chromatin condensation.	CASP3 ACIN1	4.84e-06	2	77	2	10490026
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	CEP170 CCNT2 GTF3C1 MAP1S PNN CDK13 CLK3 OSBPL8 KMT2A MLLT1 THRAP3	5.13e-06	910	77	11	36736316
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	MSH6 LOXHD1 GTF3C1 MLLT1 PRPF38B BOD1L1 REV3L ZBTB11 CXXC1 PPM1A	5.19e-06	736	77	10	29676528
Pubmed	Dynamic protein-protein interaction wiring of the human spliceosome.	FRA10AC1 SRSF4 PRPF3 U2SURP ACIN1 PRPF40A	5.19e-06	197	77	6	22365833
Pubmed	Folate receptor α increases chemotherapy resistance through stabilizing MDM2 in cooperation with PHB2 that is overcome by MORAb-202 in gastric cancer.	RBBP6 U2SURP PRPF38B ZCCHC17 RP9 PRPF40A	6.71e-06	206	77	6	34185411
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	CEP170 MSH6 SRSF4 GTF3C1 GLYR1 NEMF UHRF1 KMT2A THRAP3	7.35e-06	601	77	9	33658012
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	TNIK CEP170 NHSL1 MAP1S GLYR1 U2SURP OSBPL8 PRPF38B CAMSAP1 THRAP3 OPA1 UNC13A	7.42e-06	1139	77	12	36417873
Pubmed	Phosphoproteome analysis of the human mitotic spindle.	MSH6 PNN PRPF3 KMT2A AATF THRAP3	7.49e-06	210	77	6	16565220
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TNIK CEP170 STOX2 TCF20 TBC1D5 BCOR CAMSAP1 THRAP3 OPA1 UNC13A ANKS1A	8.74e-06	963	77	11	28671696
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	GTF3C1 RBBP6 CDK13 UHRF1 KMT2A ACIN1 BOD1L1 ANKS1A	9.61e-06	469	77	8	27634302
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	GTF3C1 PNN PRPF3 KMT2A AATF BCOR JMJD1C	1.05e-05	339	77	7	30415952
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	TCF20 GTF3C1 RBBP6 KMT2A ACIN1 JMJD1C THRAP3	1.09e-05	341	77	7	32971831
Pubmed	Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.	CEP170 MSH6 SRSF4 CLK3 U2SURP ACIN1 BOD1L1 KATNAL1 PRPF40A LARP7	1.18e-05	809	77	10	32129710
Pubmed	Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.	TNIK CDK13 TBC1D5 THRAP3 OPA1	1.20e-05	133	77	5	15144186
Pubmed	A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.	SRSF4 PRPF3 U2SURP RBM15B ACIN1 ZCCHC17 LARP7	1.22e-05	347	77	7	16033648
Pubmed	Human Regulatory Protein Ki-1/57 Is a Target of SUMOylation and Affects PML Nuclear Body Formation.	PRPF3 GLYR1 NEMF UHRF1 LARP7	1.25e-05	134	77	5	28695742
Interaction	SRPK2 interactions	CEP170 SRSF4 MAP1S PNN RBBP6 CDK13 CLK3 DBF4B GLYR1 U2SURP RBM15B ACIN1 AATF PRPF38B ZCCHC17 MYO18B RSRC2 CAMSAP1 PRPF40A JMJD1C THRAP3 LARP7	1.57e-14	717	77	22	int:SRPK2
Interaction	SRSF4 interactions	SRSF4 PNN RBBP6 NSD2 CDK13 CLK3 GLYR1 U2SURP KMT2A ACIN1 AATF ZBTB11 THRAP3 LARP7	7.02e-12	300	77	14	int:SRSF4
Interaction	SMC5 interactions	CEP170 SRSF4 TCF20 PNN SLF2 PRPF3 RBBP6 NSD2 U2SURP RBM15B KMT2A ACIN1 MLLT1 AATF BOD1L1 RP9 REV3L BCOR PRPF40A TOR1AIP1 JMJD1C THRAP3	1.20e-11	1000	77	22	int:SMC5
Interaction	MECP2 interactions	CEP170 CCNT2 MSH6 SRSF4 TCF20 GTF3C1 PNN PRPF3 RBBP6 NSD2 CLK3 GLYR1 U2SURP NEMF RBM15B ACIN1 PRPF38B ZCCHC17 RSRC2 CXXC1 PRPF40A THRAP3 OPA1 UNC13A	3.54e-11	1287	77	24	int:MECP2
Interaction	SRSF6 interactions	SRSF4 PNN RBBP6 NSD2 CDK13 CLK3 GLYR1 U2SURP KMT2A ACIN1 AATF PRPF38B ZCCHC17 ZBTB11 THRAP3 LARP7	6.03e-11	503	77	16	int:SRSF6
Interaction	DDX23 interactions	MSH6 SRSF4 PNN PRPF3 RBBP6 CDK13 U2SURP ACIN1 MLLT1 AATF RP9 RSRC2 PRPF40A THRAP3 LARP7	3.30e-10	480	77	15	int:DDX23
Interaction	HECTD1 interactions	CEP170 MSH6 GTF3C1 PNN PRPF3 RBBP6 NSD2 CDK13 GLYR1 U2SURP NEMF RBM15B UHRF1 ACIN1 AATF PRPF38B ZCCHC17 ZBTB11 PRPF40A LARP7	5.10e-10	984	77	20	int:HECTD1
Interaction	NUP43 interactions	CCNT2 TCF20 PNN SLF2 RBBP6 NSD2 GLYR1 KMT2A ACIN1 AATF BOD1L1 BCOR ZBTB11 JMJD1C LARP7 PPM1A	1.43e-09	625	77	16	int:NUP43
Interaction	SNRNP70 interactions	CEP170 CCNT2 MSH6 SRSF4 GTF3C1 PNN PRPF3 RBBP6 CLK3 U2SURP RBM15B CASP3 ACIN1 PRPF38B RSRC2 SKIL PRPF40A THRAP3 LARP7	3.52e-09	984	77	19	int:SNRNP70
Interaction	IFI16 interactions	CEP170 MSH6 SRSF4 PNN PRPF3 NSD2 GLYR1 U2SURP NEMF OSBPL8 ACIN1 AATF RP9 PRPF40A TOR1AIP1 LARP7	9.51e-09	714	77	16	int:IFI16
Interaction	DHX8 interactions	SRSF4 TCF20 PNN PRPF3 RBBP6 CDK13 U2SURP RSRC2 BCOR PRPF40A THRAP3	1.40e-08	292	77	11	int:DHX8
Interaction	SIRT7 interactions	CEP170 MSH6 SRSF4 TCF20 GTF3C1 PNN NSD2 GLYR1 U2SURP OSBPL8 KMT2A ACIN1 AATF ZBTB11 PRPF40A LARP7	1.69e-08	744	77	16	int:SIRT7
Interaction	NAA40 interactions	TNIK CEP170 MSH6 PNN PRPF3 RBBP6 TBC1D5 U2SURP CASP3 KMT2A ACIN1 PRPF38B BOD1L1 BCOR CAMSAP1 PRPF40A TOR1AIP1 ANKS1A	2.07e-08	978	77	18	int:NAA40
Interaction	RNF151 interactions	PNN PRPF3 NSD2 CLK3 GLYR1 ACIN1 ZBTB11 LARP7	2.26e-08	123	77	8	int:RNF151
Interaction	MYCN interactions	CEP170 SRSF4 TCF20 GTF3C1 PNN PRPF3 RBBP6 CDK13 GLYR1 U2SURP RBM15B UHRF1 KMT2A ACIN1 AATF PRPF38B ZCCHC17 RP9 PRPF40A THRAP3 LARP7	2.71e-08	1373	77	21	int:MYCN
Interaction	YWHAG interactions	CEP170 NHSL1 STOX2 PNN CLK3 TBC1D5 RBM15B OSBPL8 CASP3 KMT2A ACIN1 PRPF38B BOD1L1 PRKCZ CAMSAP1 PRPF40A THRAP3 TMCC3 FAM83B ANKS1A	2.93e-08	1248	77	20	int:YWHAG
Interaction	GLDC interactions	CEP170 SRSF4 TCF20 PNN PRPF3 RBBP6 UHRF1 ACIN1 PRPF40A THRAP3 LARP7	3.70e-08	321	77	11	int:GLDC
Interaction	DOT1L interactions	SRSF4 GTF3C1 PNN PRPF3 RBBP6 GLYR1 U2SURP RBM15B KMT2A ACIN1 MLLT1 AATF PRPF40A TOR1AIP1 THRAP3 LARP7	5.24e-08	807	77	16	int:DOT1L
Interaction	CIT interactions	TNIK CEP170 MSH6 TCF20 PNN PRPF3 RBBP6 DBF4B GLYR1 UHRF1 KMT2A ACIN1 AATF PRPF38B BOD1L1 RP9 CMYA5 RALGAPA2 PRPF40A TOR1AIP1 THRAP3	6.92e-08	1450	77	21	int:CIT
Interaction	SRSF7 interactions	SRSF4 GTF3C1 PNN PRPF3 RBBP6 CLK3 GLYR1 U2SURP ACIN1 PRPF40A THRAP3 LARP7	7.06e-08	425	77	12	int:SRSF7
Interaction	SNRNP40 interactions	CCNT2 TCF20 PNN PRPF3 RBBP6 NSD2 KMT2A ACIN1 AATF RP9 BCOR ZBTB11 PRPF40A LARP7	1.15e-07	637	77	14	int:SNRNP40
Interaction	TERF2IP interactions	TCF20 GTF3C1 RBBP6 NSD2 CDK13 U2SURP KMT2A BOD1L1 RSRC2 BCOR PRPF40A TOR1AIP1 LARP7	1.57e-07	552	77	13	int:TERF2IP
Interaction	CLK3 interactions	SRSF4 PNN RBBP6 CLK3 ACIN1 MLLT1 PRPF38B THRAP3 LARP7	1.58e-07	220	77	9	int:CLK3
Interaction	NKAPD1 interactions	SRSF4 PNN PRPF3 CLK3 ACIN1 RP9 PRPF40A THRAP3	1.84e-07	161	77	8	int:NKAPD1
Interaction	CENPA interactions	MSH6 TCF20 GTF3C1 SLF2 NSD2 GLYR1 UHRF1 KMT2A MLLT1 AATF TOR1AIP1	1.88e-07	377	77	11	int:CENPA
Interaction	MEN1 interactions	SRSF4 TCF20 GTF3C1 PNN PRPF3 RBBP6 GLYR1 U2SURP KMT2A ACIN1 AATF BOD1L1 CXXC1 PRPF40A TOR1AIP1 JMJD1C THRAP3	2.57e-07	1029	77	17	int:MEN1
Interaction	BRD3 interactions	GTF3C1 PNN PRPF3 RBBP6 NSD2 UHRF1 KMT2A ACIN1 ZNF740 RSRC2 PRPF40A LARP7	3.57e-07	494	77	12	int:BRD3
Interaction	SNIP1 interactions	SRSF4 PNN PRPF3 CDK13 CLK3 RBM15B ACIN1 AATF PRPF40A THRAP3 TMCC3	5.12e-07	417	77	11	int:SNIP1
Interaction	CSNK2A1 interactions	CEP170 MSH6 PNN OSBPL8 KMT2A ACIN1 MLLT1 ZCCHC17 RP9 PRKCZ SNAPC4 BCOR PRPF40A TOR1AIP1 THRAP3 LARP7	5.20e-07	956	77	16	int:CSNK2A1
Interaction	H2AJ interactions	RBBP6 PRPF38B ZCCHC17 RP9 CXXC1 PRPF40A LARP7	5.57e-07	127	77	7	int:H2AJ
Interaction	RNPS1 interactions	SRSF4 GTF3C1 PNN PRPF3 RBBP6 CLK3 ACIN1 AATF ZCCHC17 PRPF40A THRAP3	6.17e-07	425	77	11	int:RNPS1
Interaction	YWHAH interactions	CEP170 NHSL1 STOX2 TCF20 PNN SLF2 CLK3 TBC1D5 RBM15B OSBPL8 KMT2A BOD1L1 PRKCZ CAMSAP1 TMCC3 FAM83B ANKS1A	6.73e-07	1102	77	17	int:YWHAH
Interaction	CLK2 interactions	SRSF4 PNN RBBP6 CLK3 ACIN1 MLLT1 THRAP3 LARP7	7.91e-07	195	77	8	int:CLK2
Interaction	THRAP3 interactions	TNIK SRSF4 PNN PRPF3 RBBP6 NSD2 CLK3 ACIN1 AATF THRAP3 LARP7	9.27e-07	443	77	11	int:THRAP3
Interaction	ZNF330 interactions	MSH6 TCF20 GTF3C1 NSD2 GLYR1 UHRF1 KMT2A MLLT1 AATF ZBTB11 LARP7	9.91e-07	446	77	11	int:ZNF330
Interaction	JMJD6 interactions	CLK3 U2SURP PRPF38B ZCCHC17 RP9 RSRC2 PRPF40A LARP7	1.15e-06	205	77	8	int:JMJD6
Interaction	OBSL1 interactions	TCF20 GTF3C1 PNN PRPF3 GLYR1 U2SURP NEMF UHRF1 ACIN1 AATF PRPF38B CXXC1 PRPF40A THRAP3 LARP7	1.35e-06	902	77	15	int:OBSL1
Interaction	CEBPB interactions	CEP170 MSH6 SRSF4 TCF20 PNN PRPF3 CDK13 U2SURP UHRF1 ACIN1 MLLT1 AATF RP9 SKIL PRPF40A TOR1AIP1 LRRD1 THRAP3 OPA1	1.44e-06	1443	77	19	int:CEBPB
Interaction	SRSF5 interactions	SRSF4 GTF3C1 PRPF3 NSD2 CDK13 CLK3 GLYR1 U2SURP KMT2A ZBTB11 LARP7	1.79e-06	474	77	11	int:SRSF5
Interaction	H2BC8 interactions	MSH6 TCF20 GTF3C1 NSD2 GLYR1 UHRF1 KMT2A RP9 RSRC2 BCOR CXXC1 TOR1AIP1	1.79e-06	576	77	12	int:H2BC8
Interaction	RNF113A interactions	MSH6 GTF3C1 PNN RBBP6 CDK13 U2SURP ACIN1 RP9 ZBTB11 PRPF40A THRAP3 OPA1 FAM83B	2.00e-06	692	77	13	int:RNF113A
Interaction	TOP1 interactions	MSH6 TCF20 GTF3C1 PNN PRPF3 RBBP6 NSD2 CASP3 KMT2A ACIN1 PRPF40A THRAP3 LARP7	2.13e-06	696	77	13	int:TOP1
Interaction	CHD4 interactions	MSH6 TCF20 PNN PRPF3 RBBP6 NSD2 GLYR1 U2SURP RBM15B KMT2A ACIN1 CXXC1 PRPF40A THRAP3 LARP7	2.20e-06	938	77	15	int:CHD4
Interaction	CSNK2A2 interactions	CEP170 TCF20 GTF3C1 PNN OSBPL8 KMT2A ZCCHC17 RP9 SNAPC4 BCOR PRPF40A THRAP3 LARP7	3.00e-06	718	77	13	int:CSNK2A2
Interaction	ZCCHC10 interactions	FRA10AC1 GTF3C1 PRPF3 RBBP6 ZCCHC17 BICRAL ZBTB11 PRPF40A	3.30e-06	236	77	8	int:ZCCHC10
Interaction	SUPT5H interactions	CCNT2 MSH6 TCF20 GTF3C1 PNN U2SURP KMT2A ACIN1 JMJD1C THRAP3	3.39e-06	408	77	10	int:SUPT5H
Interaction	CEBPA interactions	CEP170 CCNT2 MSH6 TCF20 GTF3C1 PNN PRPF3 CDK13 U2SURP KMT2A ACIN1 PRPF38B BICRAL RSRC2 BCOR JMJD1C THRAP3	3.57e-06	1245	77	17	int:CEBPA
Interaction	ANKRD50 interactions	TNIK RBBP6 RBM15B PRPF38B RP9 PRPF40A	3.59e-06	108	77	6	int:ANKRD50
Interaction	ZC3H14 interactions	SRSF4 PNN CLK3 AATF ZCCHC17 RP9 THRAP3	3.78e-06	169	77	7	int:ZC3H14
Interaction	BARD1 interactions	MSH6 SRSF4 GTF3C1 PNN CDK13 U2SURP PRPF40A THRAP3 LARP7	3.87e-06	323	77	9	int:BARD1
Interaction	AR interactions	TCF20 PNN PRPF3 NSD2 U2SURP CASP3 UHRF1 KMT2A ACIN1 AATF BCOR SKIL PRPF40A JMJD1C THRAP3	4.36e-06	992	77	15	int:AR
Interaction	PRP4K interactions	CCNT2 MSH6 SRSF4 PNN PRPF3 CLK3 ACIN1 PRPF40A THRAP3	4.49e-06	329	77	9	int:PRP4K
Interaction	TRA2A interactions	SRSF4 PNN PRPF3 RBBP6 CLK3 U2SURP PRPF40A THRAP3 LARP7	4.60e-06	330	77	9	int:TRA2A
Interaction	H3-3A interactions	MSH6 TCF20 GTF3C1 NSD2 GLYR1 UHRF1 KMT2A BOD1L1 SNAPC4 BCOR ZBTB11 JMJD1C THRAP3	4.76e-06	749	77	13	int:H3-3A
Interaction	IFI27L1 interactions	RBM15B PRPF38B RP9 RSRC2 PRPF40A	4.93e-06	65	77	5	int:IFI27L1
Interaction	TERF2 interactions	CCNT2 CDK13 CLK3 RBM15B REV3L PRPF40A TOR1AIP1 THRAP3 LARP7	5.86e-06	340	77	9	int:TERF2
Interaction	CAMKV interactions	TNIK PNN OSBPL8 ACIN1 MLLT1 THRAP3	5.99e-06	118	77	6	int:CAMKV
Interaction	H3C1 interactions	MSH6 GTF3C1 PRPF3 NSD2 CDK13 GLYR1 U2SURP UHRF1 KMT2A MLLT1 CAMSAP1 JMJD1C THRAP3 LARP7	7.00e-06	901	77	14	int:H3C1
Interaction	ZBTB2 interactions	MSH6 SRSF4 TCF20 PNN NSD2 GLYR1 ACIN1 PRPF40A THRAP3 LARP7	8.04e-06	450	77	10	int:ZBTB2
Interaction	SRPK3 interactions	SRSF4 NSD2 CDK13 GLYR1 U2SURP ACIN1 THRAP3	8.17e-06	190	77	7	int:SRPK3
Interaction	PPIG interactions	SRSF4 PNN RBBP6 CLK3 PRPF40A THRAP3	9.15e-06	127	77	6	int:PPIG
Interaction	RAD18 interactions	SRSF4 SLF2 PRPF3 RBBP6 CLK3 RBM15B UHRF1 ACIN1 PRPF38B THRAP3	9.20e-06	457	77	10	int:RAD18
Interaction	EPB41L3 interactions	PNN U2SURP ACIN1 MLLT1 BOD1L1 ZCCHC17 CXXC1 UNC13A	9.35e-06	272	77	8	int:EPB41L3
Interaction	TRIR interactions	PRPF3 NSD2 U2SURP RSRC2 PRPF40A	9.36e-06	74	77	5	int:TRIR
Interaction	NCL interactions	CEP170 MSH6 GTF3C1 PNN PRPF3 NSD2 U2SURP SCN9A KMT2A AATF PRKCZ THRAP3 LARP7	9.41e-06	798	77	13	int:NCL
Interaction	SF3A2 interactions	SRSF4 PNN PRPF3 U2SURP ACIN1 PRPF40A THRAP3 LARP7	9.60e-06	273	77	8	int:SF3A2
Interaction	XRCC6 interactions	MSH6 TCF20 PRPF3 RBBP6 NSD2 GLYR1 KMT2A ACIN1 BOD1L1 SKIL PRPF40A JMJD1C THRAP3 LARP7	9.79e-06	928	77	14	int:XRCC6
Interaction	SRSF1 interactions	MSH6 SRSF4 CDK13 CLK3 GLYR1 U2SURP AATF ZBTB11 PRPF40A THRAP3 LARP7	1.04e-05	570	77	11	int:SRSF1
Interaction	GSK3A interactions	TNIK NHSL1 PNN U2SURP ACIN1 PRKCZ CAMSAP1 PRPF40A THRAP3 ANKS1A	1.05e-05	464	77	10	int:GSK3A
Interaction	NKAP interactions	FRA10AC1 PNN PRPF3 ACIN1 ZCCHC17 PRPF40A	1.14e-05	132	77	6	int:NKAP
Interaction	H2BC21 interactions	MSH6 TCF20 PNN NSD2 DBF4B GLYR1 UHRF1 KMT2A MLLT1 BCOR JMJD1C LARP7	1.23e-05	696	77	12	int:H2BC21
Interaction	SRSF11 interactions	SRSF4 PNN CLK3 ACIN1 PRPF38B PRPF40A THRAP3	1.26e-05	203	77	7	int:SRSF11
Interaction	KRR1 interactions	SRSF4 NSD2 CDK13 GLYR1 U2SURP KMT2A AATF ZBTB11 LARP7	1.40e-05	379	77	9	int:KRR1
Interaction	PSENEN interactions	FRA10AC1 NEMF RBM15B PRPF38B RSRC2	1.46e-05	81	77	5	int:PSENEN
Interaction	THOC1 interactions	FRA10AC1 PRPF3 RBBP6 RBM15B AATF PRPF40A THRAP3	1.57e-05	210	77	7	int:THOC1
Interaction	DDX21 interactions	SRSF4 PNN PRPF3 NSD2 GLYR1 U2SURP ACIN1 AATF ZCCHC17 PRPF40A THRAP3 LARP7	1.68e-05	718	77	12	int:DDX21
Interaction	SNRPA1 interactions	GTF3C1 PNN PRPF3 U2SURP ACIN1 PRPF40A THRAP3 LARP7	1.90e-05	300	77	8	int:SNRPA1
Interaction	ACIN1 interactions	SRSF4 PNN RBBP6 CLK3 CASP3 ACIN1 PRPF40A THRAP3	1.94e-05	301	77	8	int:ACIN1
Interaction	EIF4A3 interactions	SRSF4 TCF20 HTR6 PNN PRPF3 RBBP6 ACIN1 PRPF40A THRAP3 LARP7	1.97e-05	499	77	10	int:EIF4A3
Interaction	PNN interactions	SRSF4 PNN RBBP6 CLK3 ACIN1 ZCCHC17 PRPF40A THRAP3	1.99e-05	302	77	8	int:PNN
Interaction	PSME3 interactions	CLK3 CASP3 ZCCHC17 RP9 PRKCZ REV3L SNAPC4 PRPF40A THRAP3	2.06e-05	398	77	9	int:PSME3
Interaction	SAP18 interactions	GTF3C1 PNN RBBP6 CLK3 ACIN1 PRPF38B PRPF40A THRAP3	2.14e-05	305	77	8	int:SAP18
Interaction	RNF2 interactions	GTF3C1 CDK13 GLYR1 CASP3 UHRF1 KMT2A ACIN1 MLLT1 ZNF740 BCOR CXXC1 THRAP3 LARP7	2.24e-05	866	77	13	int:RNF2
Interaction	H1-1 interactions	NSD2 GLYR1 U2SURP AATF PRKCZ REV3L CMYA5 ZBTB11 THRAP3 LARP7	2.25e-05	507	77	10	int:H1-1
Interaction	PURG interactions	RBBP6 CDK13 CLK3 GLYR1 U2SURP ZBTB11 LARP7	2.30e-05	223	77	7	int:PURG
Interaction	ARRDC3 interactions	TNIK PNN RBBP6 U2SURP RBM15B PRPF40A THRAP3	2.37e-05	224	77	7	int:ARRDC3
Interaction	CSNK2B interactions	CEP170 U2SURP OSBPL8 KMT2A ZCCHC17 RP9 PRKCZ SNAPC4 BCOR THRAP3 LARP7	2.44e-05	625	77	11	int:CSNK2B
Interaction	CCNT1 interactions	CCNT2 CLK3 RBM15B KMT2A MLLT1 PRPF40A LARP7	2.44e-05	225	77	7	int:CCNT1
Interaction	ZC3H18 interactions	SRSF4 PNN PRPF3 RBBP6 CLK3 U2SURP RBM15B ACIN1 PRPF38B RSRC2 BCOR PRPF40A THRAP3	2.55e-05	877	77	13	int:ZC3H18
Interaction	NFKBIL1 interactions	PNN ACIN1 SNAPC4 CXXC1 PRPF40A	2.85e-05	93	77	5	int:NFKBIL1
Interaction	HABP4 interactions	FRA10AC1 PRPF3 GLYR1 NEMF PRKCZ LARP7	2.94e-05	156	77	6	int:HABP4
Interaction	LINC02910 interactions	U2SURP RBM15B PRPF38B RP9 RSRC2	3.16e-05	95	77	5	int:LINC02910
Interaction	WWTR1 interactions	CEP170 MSH6 TCF20 GTF3C1 PNN KMT2A BCOR PRPF40A JMJD1C	3.26e-05	422	77	9	int:WWTR1
Interaction	CBX3 interactions	TCF20 GTF3C1 PRPF3 RBBP6 NSD2 GLYR1 UHRF1 KMT2A RP9 BCOR TOR1AIP1	3.30e-05	646	77	11	int:CBX3
Interaction	MKI67 interactions	SRSF4 GTF3C1 PNN PRPF3 NSD2 CDK13 UHRF1 KMT2A ACIN1 CXXC1 OPA1	3.39e-05	648	77	11	int:MKI67
Interaction	CPNE4 interactions	GTF3C1 NSD2 BCOR SKIL	3.66e-05	49	77	4	int:CPNE4
Interaction	LARP4B interactions	PNN RBBP6 NSD2 CLK3 GLYR1 U2SURP LARP7	3.68e-05	240	77	7	int:LARP4B
Interaction	BRD2 interactions	CEP170 PNN PRPF3 NSD2 UHRF1 ACIN1 ZNF740 BICRAL LARP7	3.70e-05	429	77	9	int:BRD2
Interaction	LUC7L interactions	PNN RBBP6 CLK3 ACIN1 PRPF38B PRPF40A THRAP3	3.88e-05	242	77	7	int:LUC7L
Interaction	SNRPC interactions	SRSF4 PNN PRPF3 RBBP6 CLK3 ACIN1 PRPF40A THRAP3 LARP7	4.51e-05	440	77	9	int:SNRPC
GeneFamily	PWWP domain containing	MSH6 NSD2 GLYR1	2.45e-05	22	47	3	1147
GeneFamily	PHD finger proteins	NSD2 UHRF1 KMT2A CXXC1	8.69e-05	90	47	4	88
GeneFamily	Zinc fingers CXXC-type	KMT2A CXXC1	4.29e-04	12	47	2	136
GeneFamily	RNA binding motif containing	SRSF4 U2SURP RBM15B LARP7	2.25e-03	213	47	4	725
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	NSD2 KMT2A	3.52e-03	34	47	2	487
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	TERB1 SNAPC4	8.38e-03	53	47	2	532
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	CCNT2 PNN SLF2 RBBP6 CDK13 U2SURP NEMF OSBPL8 KMT2A PRPF38B BOD1L1 REV3L RSRC2 PRPF40A TOR1AIP1 JMJD1C THRAP3 PPM1A	2.34e-07	1492	77	18	M40023
Coexpression	CHEN_HOXA5_TARGETS_9HR_UP	CCNT2 PRPF3 RBBP6 NEMF CASP3 PRPF38B RSRC2 JMJD1C	3.08e-07	223	77	8	M17621
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	CEP170 FRA10AC1 STOX2 PNN NEMF OSBPL8 PRPF38B REV3L RSRC2 ZBTB11 OPA1 LARP7	4.55e-07	656	77	12	M18979
Coexpression	NAKAYA_PBMC_FLUMIST_AGE_18_50YO_3DY_DN	TNIK PRPF3 RBBP6 CASP3 BOD1L1 RALGAPA2 ZBTB11 JMJD1C OPA1 TMCC3 PPM1A	4.67e-06	680	77	11	M41089
Coexpression	NAKAYA_PBMC_FLUARIX_FLUVIRIN_AGE_18_50YO_3DY_DN	CCNT2 PNN RBBP6 U2SURP PRKCZ RSRC2 ZBTB11 JMJD1C PPM1A	4.95e-06	432	77	9	M41149
Coexpression	GEORGES_TARGETS_OF_MIR192_AND_MIR215	NHSL1 MSH6 STOX2 SLF2 NSD2 DBF4B OSBPL8 BICRAL BCOR TOR1AIP1 OPA1 PPM1A	1.08e-05	892	77	12	M18120
Coexpression	NAKAYA_MYELOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_UP	TCF20 CLK3 GLYR1 SCN9A AATF SKIL TOR1AIP1 ANKS1A	1.54e-05	378	77	8	M41174
Coexpression	FAN_OVARY_CL15_SMALL_ANTRAL_FOLLICLE_GRANULOSA_CELL	MSH6 PNN RBBP6 U2SURP ACIN1 PRPF38B REV3L RSRC2 SKIL PRPF40A	1.87e-05	644	77	10	M41717
Coexpression	PYEON_CANCER_HEAD_AND_NECK_VS_CERVICAL_UP	SLF2 U2SURP UHRF1 SKIL OPA1 PPM1A	2.40e-05	195	77	6	M13736
Coexpression	GSE16266_CTRL_VS_LPS_STIM_MEF_UP	CEP170 MAP1S BCOR CAMSAP1 SKIL TMCC3	2.62e-05	198	77	6	M7219
Coexpression	GSE360_L_MAJOR_VS_B_MALAYI_LOW_DOSE_MAC_DN	ZNF134 GTF3C1 NEMF MLLT1 AATF TOR1AIP1	2.69e-05	199	77	6	M5251
Coexpression	GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_HET_4H_DN	SRSF4 UHRF1 REV3L PRPF40A THRAP3 ANKS1A	2.69e-05	199	77	6	M8707
Coexpression	GSE3039_ALPHABETA_CD8_TCELL_VS_B1_BCELL_UP	CCNT2 CDK13 TERB1 ZNF740 AATF PNPLA7	2.77e-05	200	77	6	M6447
Coexpression	SHEN_SMARCA2_TARGETS_UP	U2SURP NEMF OSBPL8 PRPF38B RSRC2 CAMSAP1 TOR1AIP1 LARP7	3.79e-05	429	77	8	M29
Coexpression	RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP	MSH6 PNN RBBP6 U2SURP NEMF OSBPL8 BOD1L1 CAMSAP1 ZBTB11 PRPF40A	4.85e-05	721	77	10	M10237
Coexpression	PUJANA_ATM_PCC_NETWORK	CCNT2 MSH6 ZNF134 TCF20 PNN RBBP6 NSD2 CDK13 TBC1D5 CASP3 AATF PRPF40A LARP7 PPM1A	4.88e-05	1394	77	14	M9585
Coexpression	NAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_UP	CCNT2 SLF2 RBBP6 CDK13 TBC1D5 U2SURP SCN9A RBM15B OSBPL8 KMT2A PRPF38B CAMSAP1 OPA1	4.96e-05	1215	77	13	M41122
Coexpression	GSE40274_FOXP3_VS_FOXP3_AND_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN	BOD1L1 REV3L SNAPC4 RSRC2 SKIL	6.49e-05	143	77	5	M9149
Coexpression	JOHNSTONE_PARVB_TARGETS_2_DN	SRSF4 CDK13 OSBPL8 CASP3 BICRAL OPA1 PPM1A	6.90e-05	344	77	7	M2239
Coexpression	FISCHER_DREAM_TARGETS	MSH6 PNN SLF2 RBBP6 NSD2 DBF4B UHRF1 TOR1AIP1 THRAP3 OPA1 LARP7	1.20e-04	969	77	11	M149
Coexpression	MARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN	CCNT2 GLYR1 NEMF MLLT1 PRPF38B RSRC2 PRPF40A THRAP3	1.42e-04	519	77	8	M3395
Coexpression	SCHERER_PBMC_APSV_WETVAX_AGE_18_32YO_50_TO_60DY_UP	PNN RBBP6 CASP3 RSRC2 PPM1A	1.43e-04	169	77	5	M40877
Coexpression	LAZARO_GENETIC_MOUSE_MODEL_HIGH_GRADE_SMALL_CELL_NEUROENDOCRINE_LUNG_CARCINOMA_UP	MSH6 NSD2 MYT1 RBM15B CASP3 UHRF1 REV3L CAMSAP1 LARP7	1.69e-04	680	77	9	MM456
Coexpression	GSE40493_BCL6_KO_VS_WT_TREG_UP	CEP170 BOD1L1 KATNAL1 RALGAPA2 OPA1	1.77e-04	177	77	5	M9401
Coexpression	GSE37533_PPARG1_FOXP3_VS_PPARG2_FOXP3_TRANSDUCED_CD4_TCELL_UP	BOD1L1 ZCCHC17 RALGAPA2 CXXC1 PRPF40A	1.82e-04	178	77	5	M8996
Coexpression	MARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN	CCNT2 GLYR1 NEMF MLLT1 PRPF38B RSRC2 PRPF40A THRAP3	1.94e-04	543	77	8	MM997
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	CEP170 MSH6 CDK13 U2SURP OSBPL8 BICRAL REV3L ZBTB11 OPA1 ANKS1A	1.99e-04	856	77	10	M4500
Coexpression	GSE2706_R848_VS_R848_AND_LPS_2H_STIM_DC_UP	ZNF134 IGFN1 SRSF4 AATF PRKCZ	2.28e-04	187	77	5	M4714
Coexpression	GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP	MSH6 NSD2 PEG3 CASP3 UHRF1 RSRC2 LARP7 ANKS1A	2.95e-04	578	77	8	M2368
Coexpression	GSE14308_NAIVE_CD4_TCELL_VS_INDUCED_TREG_UP	NEMF OSBPL8 ZNF740 ZBTB11 TOR1AIP1	3.04e-04	199	77	5	M3391
Coexpression	GSE41867_NAIVE_VS_DAY15_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_DN	RSRC2 JMJD1C THRAP3 TMCC3 ANKS1A	3.04e-04	199	77	5	M9501
Coexpression	GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_6H_DN	CEP170 OSBPL8 BOD1L1 RP9 RALGAPA2	3.04e-04	199	77	5	M6172
Coexpression	GSE16385_IFNG_TNF_VS_UNSTIM_MACROPHAGE_ROSIGLITAZONE_TREATED_DN	CCNT2 PRPF3 CDK13 BCOR PRPF40A	3.11e-04	200	77	5	M8032
Coexpression	GSE16385_ROSIGLITAZONE_IL4_VS_IFNG_TNF_STIM_MACROPHAGE_UP	CEP170 CCNT2 PRPF3 OSBPL8 PRPF40A	3.11e-04	200	77	5	M8030
Coexpression	GSE13411_SWITCHED_MEMORY_BCELL_VS_PLASMA_CELL_UP	CCNT2 ZNF134 TCF20 PRPF3 CDK13	3.11e-04	200	77	5	M3251
Coexpression	GSE9988_ANTI_TREM1_VS_CTRL_TREATED_MONOCYTES_DN	TCF20 KMT2A ZNF740 BOD1L1 BCOR	3.11e-04	200	77	5	M5851
Coexpression	GSE27786_CD8_TCELL_VS_NKCELL_DN	OSBPL8 UHRF1 CMYA5 TOR1AIP1 TMCC3	3.11e-04	200	77	5	M4838
Coexpression	GSE17721_POLYIC_VS_GARDIQUIMOD_1H_BMDC_UP	TCF20 NEMF CASP3 KMT2A THRAP3	3.11e-04	200	77	5	M4016
Coexpression	GSE5589_LPS_VS_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_UP	NEMF BOD1L1 RP9 CALHM6 PNPLA7	3.11e-04	200	77	5	M6611
Coexpression	GSE14350_TREG_VS_TEFF_IN_IL2RB_KO_UP	CCNT2 NEMF AATF PRKCZ ZBTB11	3.11e-04	200	77	5	M3419
Coexpression	GSE557_WT_VS_CIITA_KO_DC_DN	MSH6 CLK3 ILDR1 RSRC2 SKIL	3.11e-04	200	77	5	M6008
Coexpression	GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP	MSH6 NSD2 PEG3 CASP3 UHRF1 RSRC2 LARP7 ANKS1A	3.66e-04	597	77	8	MM1309
Coexpression	MARTINEZ_RB1_AND_TP53_TARGETS_DN	NHSL1 TCF20 RBBP6 PEG3 MLLT1 AATF THRAP3 TMCC3	4.22e-04	610	77	8	M3854
Coexpression	MURARO_PANCREAS_BETA_CELL	FRA10AC1 SEMA6D GTF3C1 U2SURP PEG3 OSBPL8 KATNAL1 TOR1AIP1 TMCC3 PPM1A	4.39e-04	946	77	10	M39169
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	CEP170 CDK13 U2SURP OSBPL8 REV3L OPA1 ANKS1A	4.42e-04	466	77	7	M13522
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3	MSH6 PNN RBBP6 NSD2 NEMF CASP3 PRPF38B BOD1L1 ZCCHC17 PNPLA7 REV3L RSRC2 CAMSAP1 PRPF40A THRAP3 LARP7	9.16e-06	1257	77	16	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2	PNN RBBP6 TBC1D5 NEMF PRPF38B BOD1L1 RP9 REV3L	1.69e-05	311	77	8	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3	MSH6 PNN NEMF ACIN1 ZCCHC17 RSRC2 PRPF40A THRAP3 OPA1 LARP7	2.18e-05	532	77	10	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlas	FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_1000_k-means-cluster#1	MSH6 PNN NEMF ACIN1 RSRC2 PRPF40A LARP7	4.30e-05	259	77	7	Facebase_RNAseq_e8.5_Floor Plate_1000_K1
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500	MSH6 PNN RBBP6 NSD2 NEMF CASP3 PRPF38B BOD1L1 ZCCHC17 PNPLA7 REV3L RSRC2 CAMSAP1 PRPF40A THRAP3 LARP7	5.69e-05	1459	77	16	facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_500_k-means-cluster#5	MSH6 PNN SLF2 PRPF38B BOD1L1 ZCCHC17	5.90e-05	186	77	6	Facebase_RNAseq_e10.5_Mandibular Arch_500_K5
CoexpressionAtlas	facebase_RNAseq_e10.5_NeuroEpith_central_2500_K4	STOX2 PNN NSD2 PEG3 RBM15B CASP3 UHRF1 PRPF38B BOD1L1 REV3L BCOR CAMSAP1 RALGAPA2 THRAP3 LARP7	1.03e-04	1370	77	15	facebase_RNAseq_e10.5_NeuroEpith_central_2500_K4
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000	STOX2 PNN RBBP6 TBC1D5 MYT1 U2SURP NEMF UHRF1 PRPF38B BOD1L1 RP9 REV3L	2.19e-04	989	77	12	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlas	DevelopingGonad_e11.5_testes_emap-3226_top-relative-expression-ranked_1000	STOX2 GTF3C1 PEG3 CASP3 ACIN1 MLLT1 KATNAL1 RSRC2 CXXC1 PRPF40A LARP7	2.21e-04	843	77	11	gudmap_developingGonad_e11.5_testes_1000
CoexpressionAtlas	FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1	MSH6 PNN TBC1D5 NEMF PRPF38B RSRC2 PRPF40A PPM1A	2.96e-04	469	77	8	Facebase_RNAseq_e8.5_Floor Plate_2500_K1
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_M-vs-F_top274_274	CEP170 U2SURP PEG3 OSBPL8 PRPF40A PPM1A	3.36e-04	256	77	6	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_250_M-vs-F
CoexpressionAtlas	alpha beta T cells, T.DP.Th, 4+ 8+ TCR-/lo 69-, Thymus, avg-3	TNIK NHSL1 MSH6 NSD2 CLK3 UHRF1 PRKCZ	3.71e-04	367	77	7	GSM399391_500
ToppCell	H1299-infected-SARSCoV2\|infected / Cell line, Condition and Strain	ANKRD13D PNN RBBP6 NEMF PRPF38B BOD1L1 RSRC2 PRPF40A LARP7	6.14e-11	197	77	9	0fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell	(09)_Interm._secr.>cil.-(2)_GFP_FOXI1\|(09)_Interm._secr.>cil. / shred by cell type by condition	RBBP6 U2SURP OSBPL8 BOD1L1 REV3L PRPF40A LARP7	5.51e-08	199	77	7	fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	PNN CDK13 KMT2A ACIN1 BOD1L1 RSRC2 JMJD1C	5.71e-08	200	77	7	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	10x3'2.3-week_14-16-Lymphocytic_B-B_lineage-pro_B_progenitor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PNN CDK13 UHRF1 CALHM6 RSRC2 JMJD1C	1.09e-06	194	77	6	f64da5f62e29253d60b9546edf734ba5c17daae1
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Intermediate\|6m / Sample Type, Dataset, Time_group, and Cell type.	PNN RBBP6 SCN9A BOD1L1 RSRC2 JMJD1C	1.31e-06	200	77	6	7c261e39ac30b318511373ab7302aa53b8b81b9c
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	PNN RBBP6 CDK13 KMT2A BOD1L1 RSRC2	1.31e-06	200	77	6	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	Control-Classical_Monocyte-cMono_4\|Classical_Monocyte / Disease condition and Cell class	CEP170 MAP1S BCOR SKIL TMCC3	1.15e-05	170	77	5	9e328e1f904c77dcce8aee4df775d7f0ac725775
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PNN PEG3 CMYA5 JMJD1C THRAP3	1.36e-05	176	77	5	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	COVID-19-Heart-Lymph_EC\|Heart / Disease (COVID-19 only), tissue and cell type	NHSL1 STOX2 SCN9A PRKCZ RALGAPA2	1.48e-05	179	77	5	411620201a860716a8773b92f50f7b94ef34a586
ToppCell	Control-Classical_Monocyte-cMono_4\|Control / Disease condition and Cell class	CEP170 MAP1S BCOR SKIL TMCC3	1.56e-05	181	77	5	f3e1d8fe5cf1eba19e51c3680a55306cae687fe9
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLF2 CASP3 KMT2A JMJD1C THRAP3	1.69e-05	184	77	5	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	TNIK RBBP6 BOD1L1 PRPF40A FAM83B	1.78e-05	186	77	5	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	droplet-Tongue-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEMF PRPF38B RSRC2 PRPF40A TMCC3	1.87e-05	188	77	5	d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCell	H1299-infected\|H1299 / Cell line, Condition and Strain	PNN NSD2 KMT2A PRPF38B BOD1L1	2.07e-05	192	77	5	9cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCell	COVID-19_Mild\|World / Disease group, lineage and cell class	PNN BOD1L1 RSRC2 SKIL JMJD1C	2.34e-05	197	77	5	5c33454b10023decd2f5ccda9229b6512659711e
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	CEP170 RBBP6 PRPF38B BOD1L1 PRPF40A	2.40e-05	198	77	5	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class (2021.03.09)	PNN BOD1L1 RSRC2 SKIL JMJD1C	2.40e-05	198	77	5	44417089b62056269cac38d3134ff209c05b7007
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PNN BOD1L1 RSRC2 SKIL JMJD1C	2.40e-05	198	77	5	28ef3fc4c17dcb765537b75917f7db78baa522db
ToppCell	(10)_Ciliated-(2)_GFP_FOXI1\|(10)_Ciliated / shred by cell type by condition	RBBP6 NEMF OSBPL8 BOD1L1 PRPF40A	2.46e-05	199	77	5	61b1ed2db71b96157b92b7535d1955a4033098da
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	U2SURP OSBPL8 BOD1L1 REV3L LARP7	2.46e-05	199	77	5	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M\|organoid_Kanton_Nature / Sample Type, Dataset, Time_group, and Cell type.	TNIK CEP170 SEMA6D OSBPL8 BOD1L1	2.46e-05	199	77	5	b2d7dea11207cca63d688f8051143850b29dbdf0
ToppCell	COVID-19-COVID-19_Mild\|COVID-19 / Disease, condition lineage and cell class	ANKRD13D PNN BOD1L1 SKIL JMJD1C	2.52e-05	200	77	5	62c25042086f1afd1102e0720e933c2e476468fd
ToppCell	LPS-IL1RA+antiTNF-Unknown-Endothelial\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SEMA6D KATNAL1 MYO18B TMCC3	8.11e-05	132	77	4	46c80eab16a70da9f363a9fbdf50bccab0b287d7
ToppCell	LPS-IL1RA+antiTNF-Unknown\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SEMA6D KATNAL1 MYO18B TMCC3	8.11e-05	132	77	4	a022c3c41654166cb106f27dc54fa88e8c40f898
Drug	radicicol, diheterospora chlamydosporia; Down 200; 0.1uM; MCF7; HT_HG-U133A	MSH6 U2SURP RBM15B CASP3 SNAPC4 SKIL ANKS1A	4.40e-06	195	77	7	6979_DN
Drug	Clozapine	TNIK HTR6 OSBPL8 CASP3 KMT2A PRPF38B PRKCZ UNC13A PPM1A	6.69e-06	390	77	9	ctd:D003024
Disease	polybrominated biphenyl measurement, gestational serum measurement, fetal genotype effect measurement, polybrominated diphenyl ether measurement	LOXHD1 TBC1D5	3.45e-04	11	75	2	EFO_0007959, EFO_0007961, EFO_0007962, EFO_0007964
Disease	leukemia	MSH6 KMT2A PRKCZ	3.76e-04	55	75	3	C0023418
Disease	transient cerebral ischemia (implicated_via_orthology)	CASP3 KMT2A OPA1	5.88e-04	64	75	3	DOID:224 (implicated_via_orthology)
Disease	Tourette syndrome, schizophrenia	TCF20 TBC1D5	9.50e-04	18	75	2	EFO_0004895, MONDO_0005090
Disease	diet measurement, body mass index	FRA10AC1 CMYA5	1.18e-03	20	75	2	EFO_0004340, EFO_0008111
Disease	phospholipid measurement, intermediate density lipoprotein measurement	TBC1D5 JMJD1C ANKS1A	2.08e-03	99	75	3	EFO_0004639, EFO_0008595
Disease	Disorder of eye	PRPF3 RP9 BCOR OPA1	2.11e-03	212	75	4	C0015397
Disease	Adenoid Cystic Carcinoma	UHRF1 BCOR JMJD1C	2.14e-03	100	75	3	C0010606
Disease	cytotoxicity measurement, response to clozapine	MYT1 TMCC3	2.48e-03	29	75	2	EFO_0006952, GO_0097338
Disease	Bilateral Wilms Tumor	MLLT1 BCOR	2.48e-03	29	75	2	C2930471

Protein segments in the cluster

Peptide	Gene	Start	Entry
RAAEKSSKHGAEDRT	UNC13A	606	Q9UPW8
HSPRKSSSISEEKGD	ACIN1	201	Q9UKV3
KTKSRSTDVGSRADG	CEP170	991	Q5SW79
GVESADSRRLATKHS	HTR6	246	P50406
KIKVSSSERHSSSDE	CCNT2	526	O60583
TEHLSDQDKSRSKAG	ANKRD13D	281	Q6ZTN6
SSKRSSRSVEDDKEG	CLK3	276	P49761
GKTKDHRRSSSSRSQ	ANKS1A	471	Q92625
RVDRKRKVSGDSSHT	BCOR	1131	Q6W2J9
RDVSKEDHSKRSSFV	CASP3	101	P42574
KSVHREESCSDSGTK	CAMSAP1	1371	Q5T5Y3
SSSSSRKDRDSKAHR	CDK13	266	Q14004
RKENHSSEGTKESSS	RBM15B	636	Q8NDT2
ESTSSSGRKSKRNEE	LRRD1	66	A4D1F6
ESKESVGSRDSSKRE	MAP1S	471	Q66K74
SDSKSQSRRHLSAKE	NEMF	806	O60524
KDRVSERSSAGAHKT	JMJD1C	1326	Q15652
SVTTGKHKDAATDSR	LOXHD1	1426	Q8IVV2
DTKVDSSPRRKHSSS	FAM83B	821	Q5T0W9
ESKSSGSSHARIKSR	NHSL1	441	Q5SYE7
EESSHKKSRLSSAEE	FRA10AC1	241	Q70Z53
ERSHKSSKGGSSRDT	PNN	661	Q9H307
HDLGAASVRSTKTEK	NSD2	1326	O96028
RRAKGKDQTSSHNSS	GLYR1	91	Q49A26
KGSVERRSEKDSSHS	ILDR1	526	Q86SU0
RTGKRKRSSSEDAES	LARP7	291	Q4G0J3
SLKEKEEDSSGHTRA	MSH6	541	P52701
KEASSESSGHKRSSS	RALGAPA2	466	Q2PPJ7
KKSTHRRGICEDESS	PEG3	296	Q9GZU2
SDEHPGSSVASKSRK	PNPLA7	406	Q6ZV29
SSKEARTSDKHDSTR	RBBP6	1446	Q7Z6E9
SKKRRHKSDSPESDA	PRPF40A	876	O75400
REGKEHDLSVSSDST	OSBPL8	276	Q9BZF1
TDRGSESDKHFRKVS	OPA1	196	O60313
DSTSTRLERKLSDGH	BOD1L1	1006	Q8NFC6
KEVDSSHEKARGNSS	BOD1L1	1046	Q8NFC6
HKKSRERDGNERDSS	CXXC1	86	Q9P0U4
RKTSSRSDHGTESKL	BICRAL	941	Q6AI39
NRKEKTHSIRSTEGD	CALHM6	281	Q5R3K3
SRREVKAESSGKSHR	DBF4B	91	Q8NFT6
KTSSSQHSDKSEEAR	CMYA5	1476	Q8N3K9
TGRKKSSSHDSGTDI	KMT2A	931	Q03164
TSADHKLQSRRSGKD	IGFN1	406	Q86VF2
SDRSFRRKKDSVESH	FAM102A	301	Q5T9C2
HRERPRKDSESKSSS	MLLT1	201	Q03111
EEGRSSRHSKSSSDR	PRPF3	71	O43395
RGTSDEHEASRRVKS	KATNAL1	316	Q9BW62
RSKEGRRHESKDKSS	RSRC2	66	Q7L4I2
KEHSSDKGRERLNSS	RSRC2	91	Q7L4I2
SPSRSVSKEREHAKS	SRSF4	406	Q08170
EDRSSSSSSEGKEKH	RP9	171	Q8TA86
NGASRSSKDISKDHL	TMCC3	146	Q9ULS5
SKSISRQSEKAHSSG	SKIL	431	P12757
SKSESEDSIRRKSFH	SCN9A	501	Q15858
KDKERSSSKECSGHS	SLF2	501	Q8IX21
RSRSSHKDSPRDVSK	U2SURP	966	O15042
GDHRESKKSRSHSAK	AATF	131	Q9NY61
RETSGEKKRSGHSDS	TNIK	906	Q9UKE5
EASGTSSEKGRTKRE	ZBTB11	636	O95625
SSHSRERSAEKTEKT	THRAP3	746	Q9Y2W1
KARSRDSDESGDKTT	TOR1AIP1	236	Q5JTV8
SDSESDTGKRARHTS	ZCCHC17	206	Q9NP64
DTGKRARHTSKDSKA	ZCCHC17	211	Q9NP64
HKATSSSRSEPEGRK	REV3L	3016	O60673
SEKKHGADRSGSTAV	PPM1A	116	P35813
RSHSKTRVSKGDPSD	STOX2	371	Q9P2F5
HAKSKREEAADRSSE	STYXL2	496	Q5VZP5
SRSKERSHKRDHSDS	PRPF38B	501	Q5VTL8
SSTEDKGRLLHSSKE	TCF20	1276	Q9UGU0
VRHKSASNGSKTDTE	TCF20	1751	Q9UGU0
RARSTNVHSKTSGDK	MYO18B	2176	Q8IUG5
KSSTHGEAAAETDSR	UHRF1	106	Q96T88
AQEASKSASHKGSRR	SNAPC4	851	Q5SXM2
RSRSHSKTMGRKESE	TBC1D5	571	Q92609
EESLDKTSHSVGRRA	GTF3C1	1306	Q12789
SSQGHRKDSDKSRSR	ZNF740	51	Q8NDX6
TKSSSKRDHRRSVDS	SEMA6D	861	Q8NFY4
GRGSKAEDEDKSHSR	TERB1	456	Q8NA31
KRKTHRSTESGDAFH	ZNF134	156	P52741
SSSRKHDSIKDDSED	PRKCZ	216	Q05513
DKDEDTHSRKSTVTD	MYT1	351	Q01538
EVKGTTSSRSFKHSR	NECTIN4	186	Q96NY8