Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotein-lysine 6-oxidase activity

LOX LOXL1 LOXL3

5.37e-0651643GO:0004720
GeneOntologyMolecularFunctionformyltetrahydrofolate dehydrogenase activity

ALDH1L1 ALDH1L2

6.70e-0521642GO:0016155
GeneOntologyMolecularFunctionhistone H3K36 methyltransferase activity

NSD2 NSD3 SETD2

1.46e-04131643GO:0046975
GeneOntologyMolecularFunctionN-acetylglucosamine-6-sulfatase activity

SULF2 SULF1

2.00e-0431642GO:0008449
GeneOntologyMolecularFunctionJUN kinase activity

MAPK8 MAPK10

2.00e-0431642GO:0004705
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor

LOX LOXL1 LOXL3

2.82e-04161643GO:0016641
GeneOntologyMolecularFunctionnatural killer cell lectin-like receptor binding

RAET1G ULBP2 RAET1L

3.40e-04171643GO:0046703
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-NH2 group of donors

LOX LOXL1 LOXL3

5.60e-04201643GO:0016638
GeneOntologyMolecularFunctionhistone H3K36 trimethyltransferase activity

NSD2 SETD2

6.60e-0451642GO:0140955
GeneOntologyBiologicalProcesspeptidyl-lysine oxidation

LOX LOXL1 LOXL3

4.88e-0651643GO:0018057
GeneOntologyBiologicalProcessregulation of humoral immune response

CFH SUSD4 MBL2 CXCL13 CR1L PPL

8.09e-06601646GO:0002920
GeneOntologyBiologicalProcessdicarboxylic acid catabolic process

GAD2 ALDH1L1 ALDH1L2 QPRT

1.69e-05201644GO:0043649
GeneOntologyBiologicalProcessdicarboxylic acid metabolic process

GAD2 SHMT1 ALDH1L1 ALDH1L2 QPRT OGDHL HAL

3.00e-051111647GO:0043648
GeneOntologyBiologicalProcesssusceptibility to natural killer cell mediated cytotoxicity

RAET1G ULBP2 RAET1L

4.00e-0591643GO:0042271
GeneOntologyBiologicalProcessregulation of complement activation

CFH SUSD4 MBL2 CR1L

5.86e-05271644GO:0030449
GeneOntologyBiologicalProcessendocardial cushion cell differentiation

ACVR1 JAG1

6.28e-0521642GO:0061443
GeneOntologyBiologicalProcessesophagus smooth muscle contraction

SULF2 SULF1

6.28e-0521642GO:0014846
GeneOntologyBiologicalProcessprotein oxidation

LOX LOXL1 LOXL3

1.68e-04141643GO:0018158
GeneOntologyBiologicalProcessBMP signaling pathway

RGMB TMPRSS6 ACVR1 ACVR2A TRIM33 SULF1 BMPER SORL1

1.84e-041971648GO:0030509
GeneOntologyBiologicalProcess10-formyltetrahydrofolate catabolic process

ALDH1L1 ALDH1L2

1.88e-0431642GO:0009258
GeneOntologyBiologicalProcesspositive regulation of determination of dorsal identity

ACVR1 MAPK8

1.88e-0431642GO:2000017
GeneOntologyBiologicalProcessnegative regulation of cellular response to growth factor stimulus

TMPRSS6 CXCL13 TRIM33 SULF2 SULF1 BMPER SORL1

2.01e-041501647GO:0090288
GeneOntologyCellularComponentcell surface

SELE CFH MBL2 TECTB RAET1G ACVR2A CR1L IZUMO1R ST14 TYRO3 SULF2 SULF1 MRC2 KCNJ5 PKHD1 ABCB11 ULBP2 RAET1L CCL21 LY75 ENO2 SORL1

4.90e-05111116222GO:0009986
GeneOntologyCellularComponentexternal side of plasma membrane

SELE CFH MBL2 RAET1G CR1L IZUMO1R ST14 KCNJ5 PKHD1 ULBP2 RAET1L CCL21 LY75

2.10e-0451916213GO:0009897
DomainSushi

SELE CFH SUSD4 CR1L CSMD3 F13B PAPPA SEZ6L

1.04e-08521558PF00084
DomainCCP

SELE CFH SUSD4 CR1L CSMD3 F13B PAPPA SEZ6L

1.41e-08541558SM00032
DomainSUSHI

SELE CFH SUSD4 CR1L CSMD3 F13B PAPPA SEZ6L

1.90e-08561558PS50923
DomainSushi_SCR_CCP_dom

SELE CFH SUSD4 CR1L CSMD3 F13B PAPPA SEZ6L

2.20e-08571558IPR000436
DomainLysyl_oxidase

LOX LOXL1 LOXL3

5.54e-0651553IPR001695
DomainAWS

NSD2 NSD3 SETD2

5.54e-0651553SM00570
DomainLYSYL_OXIDASE

LOX LOXL1 LOXL3

5.54e-0651553PS00926
DomainAWS

NSD2 NSD3 SETD2

5.54e-0651553PS51215
DomainAWS_dom

NSD2 NSD3 SETD2

5.54e-0651553IPR006560
DomainLysyl_oxidase_CS

LOX LOXL1 LOXL3

5.54e-0651553IPR019828
DomainLysyl_oxidase

LOX LOXL1 LOXL3

5.54e-0651553PF01186
DomainFN3

FNDC3B COL6A3 TRIM42 OBSCN FSD2 TYRO3 HCFC2 USH2A SORL1

2.45e-051851559SM00060
DomainFN3

FNDC3B COL6A3 TRIM42 OBSCN FSD2 TYRO3 HCFC2 USH2A SORL1

4.35e-051991559PS50853
Domainfn3

FNDC3B TRIM42 OBSCN FSD2 TYRO3 HCFC2 USH2A SORL1

6.30e-051621558PF00041
DomainFN3_dom

FNDC3B COL6A3 TRIM42 OBSCN FSD2 TYRO3 HCFC2 USH2A SORL1

6.36e-052091559IPR003961
Domain10_FTHF_DH

ALDH1L1 ALDH1L2

6.84e-0521552IPR011407
DomainExtracellular_sulfatase

SULF2 SULF1

6.84e-0521552IPR014615
DomainExtracellular_sulfatase_C

SULF2 SULF1

6.84e-0521552IPR024609
DomainDUF3740

SULF2 SULF1

6.84e-0521552PF12548
DomainATPase_dyneun-rel_AAA

DNAH3 DYNC2H1 MDN1

1.91e-04141553IPR011704
DomainAAA_5

DNAH3 DYNC2H1 MDN1

1.91e-04141553PF07728
Domain-

ALDH1L1 ALDH1L2

2.04e-04315523.10.25.10
DomainGART_AS

ALDH1L1 ALDH1L2

2.04e-0431552IPR001555
DomainFormyl_trans_C

ALDH1L1 ALDH1L2

2.04e-0431552PF02911
DomainFormyl_trans_C

ALDH1L1 ALDH1L2

2.04e-0431552IPR005793
DomainGART

ALDH1L1 ALDH1L2

2.04e-0431552PS00373
DomainPost-SET_dom

NSD2 NSD3 SETD2

2.90e-04161553IPR003616
DomainPostSET

NSD2 NSD3 SETD2

2.90e-04161553SM00508
DomainPOST_SET

NSD2 NSD3 SETD2

2.90e-04161553PS50868
DomainLamGL

PAPPA USH2A

4.06e-0441552SM00560
DomainG8_domain

PKHD1L1 PKHD1

4.06e-0441552IPR019316
DomainG8

PKHD1L1 PKHD1

4.06e-0441552PS51484
DomainLamG-like

PAPPA USH2A

4.06e-0441552IPR006558
Domain-

ALDH1L1 ALDH1L2

4.06e-04415523.40.50.170
DomainFormyl_transf_N

ALDH1L1 ALDH1L2

4.06e-0441552IPR002376
DomainG8

PKHD1L1 PKHD1

4.06e-0441552SM01225
DomainG8

PKHD1L1 PKHD1

4.06e-0441552PF10162
DomainFormyl_trans_N

ALDH1L1 ALDH1L2

4.06e-0441552PF00551
DomainC-type_lectin_CS

SELE MBL2 MRC2 LY75

4.38e-04431554IPR018378
DomainLdl_recept_a

HSPG2 TMPRSS6 ST14 SORL1

5.22e-04451554PF00057
Domain-

HSPG2 TMPRSS6 ST14 SORL1

5.68e-044615544.10.400.10
DomainMHC_I

RAET1G ULBP2 RAET1L

6.68e-04211553PF00129
DomainMHC_I_a_a1/a2

RAET1G ULBP2 RAET1L

6.68e-04211553IPR001039
DomainLDLRA_1

HSPG2 TMPRSS6 ST14 SORL1

6.68e-04481554PS01209
Domain-

ALDH1L1 ALDH1L2

6.73e-04515521.10.1200.10
DomainPHOSPHOPANTETHEINE

ALDH1L1 ALDH1L2

6.73e-0451552PS00012
DomainFormyl_transferase_C-like

ALDH1L1 ALDH1L2

6.73e-0451552IPR011034
DomainMAPK_JNK

MAPK8 MAPK10

6.73e-0451552IPR008351
DomainPP-binding

ALDH1L1 ALDH1L2

6.73e-0451552PF00550
DomainACP_DOMAIN

ALDH1L1 ALDH1L2

6.73e-0451552PS50075
DomainLDrepeatLR_classA_rpt

HSPG2 TMPRSS6 ST14 SORL1

7.23e-04491554IPR002172
DomainLDLa

HSPG2 TMPRSS6 ST14 SORL1

7.23e-04491554SM00192
DomainLDLRA_2

HSPG2 TMPRSS6 ST14 SORL1

7.23e-04491554PS50068
DomainSEA

HSPG2 TMPRSS6 ST14

7.69e-04221553PF01390
DomainCUB

TMPRSS6 CSMD3 ST14 SEZ6L

7.81e-04501554SM00042
DomainEGF

SELE HSPG2 ZAN DNER GPR179 JAG1 TENM1 SORL1

7.86e-042351558SM00181
DomainSEA

HSPG2 TMPRSS6 ST14

8.79e-04231553PS50024
DomainSEA_dom

HSPG2 TMPRSS6 ST14

8.79e-04231553IPR000082
Domain-

TMPRSS6 CSMD3 ST14 SEZ6L

9.06e-045215542.60.120.290
DomainCUB

TMPRSS6 CSMD3 ST14 SEZ6L

9.74e-04531554PS01180
Domain-

RAET1G ULBP2 RAET1L

9.98e-042415533.30.500.10
DomainMHC_I-like_Ag-recog

RAET1G ULBP2 RAET1L

9.98e-04241553IPR011161
DomainPbH1

PKHD1L1 PKHD1

1.00e-0361552SM00710
DomainPbH1

PKHD1L1 PKHD1

1.00e-0361552IPR006626
DomainPP-bd_ACP

ALDH1L1 ALDH1L2

1.00e-0361552IPR009081
DomainCUB_dom

TMPRSS6 CSMD3 ST14 SEZ6L

1.28e-03571554IPR000859
DomainPlectin

EPPK1 PPL

1.40e-0371552PF00681
DomainPlectin_repeat

EPPK1 PPL

1.40e-0371552IPR001101
DomainPLEC

EPPK1 PPL

1.40e-0371552SM00250
DomainRICIN

GALNT2 MRC2 LY75

1.58e-03281553SM00458
DomainRICIN_B_LECTIN

GALNT2 MRC2 LY75

1.58e-03281553PS50231
DomainSpectrin_repeat

ACTN3 PPL SYNE2

1.75e-03291553IPR002017
DomainPectin_lyase_fold/virulence

PKHD1L1 PKHD1

1.85e-0381552IPR011050
DomainRicin_B_lectin

GALNT2 MRC2 LY75

1.93e-03301553IPR000772
DomainZinc_finger_PHD-type_CS

NSD2 SP110 NSD3 TRIM33

2.09e-03651554IPR019786
DomainSPEC

ACTN3 PPL SYNE2

2.33e-03321553SM00150
DomainSpectrin/alpha-actinin

ACTN3 PPL SYNE2

2.33e-03321553IPR018159
DomainActivin_recp

ACVR1 ACVR2A

2.95e-03101552PF01064
DomainActivin_recp

ACVR1 ACVR2A

2.95e-03101552IPR000472
DomainWD40_repeat_dom

RAE1 WDR4 NBEAL1 KATNB1 THOC3 RIC1 ANAPC4 FBXW7

3.42e-032971558IPR017986
DomainPHD

NSD2 SP110 NSD3 TRIM33

3.51e-03751554PF00628
DomainEGF_3

SELE HSPG2 ZAN DNER JAG1 TENM1 SORL1

3.52e-032351557PS50026
Domain-

FNDC3B HSPG2 COL6A3 ADAMTSL1 TRIM42 OBSCN FSD2 PKHD1L1 TYRO3 PKHD1 HCFC2 USH2A SORL1

3.59e-03663155132.60.40.10
DomainVWC

ZAN JAG1 BMPER

3.82e-03381553SM00214
DomainMHC_I/II-like_Ag-recog

RAET1G ULBP2 RAET1L

3.82e-03381553IPR011162
DomainEGF

SELE HSPG2 ZAN DNER JAG1

4.03e-031261555PF00008
DomainZnf_PHD-finger

NSD2 SP110 NSD3 TRIM33

4.23e-03791554IPR019787
DomainTGFB_receptor

ACVR1 ACVR2A

4.28e-03121552IPR000333
DomainMAPK

MAPK8 MAPK10

4.28e-03121552PS01351
DomainC8

ZAN BMPER

4.28e-03121552PF08742
DomainMAP_kinase_CS

MAPK8 MAPK10

4.28e-03121552IPR003527
DomainTIL

ZAN BMPER

4.28e-03121552PF01826
DomainLDLR_class-A_CS

HSPG2 ST14 SORL1

4.42e-03401553IPR023415
DomainC_TYPE_LECTIN_1

SELE MBL2 MRC2 LY75

4.43e-03801554PS00615
DomainSET

NSD2 NSD3 SETD2

4.74e-03411553PF00856
DomainEGF-like_dom

SELE HSPG2 ZAN DNER JAG1 TENM1 SORL1

4.82e-032491557IPR000742
DomainTTL

TTL TTLL10

5.03e-03131552PS51221
DomainTTL/TTLL_fam

TTL TTLL10

5.03e-03131552IPR004344
DomainUnchr_dom_Cys-rich

ZAN BMPER

5.03e-03131552IPR014853
DomainC8

ZAN BMPER

5.03e-03131552SM00832
Pubmed

Genomic structures and characterization of Rae1 family members encoding GPI-anchored cell surface proteins and expressed predominantly in embryonic mouse brain.

RAE1 RAET1G ULBP2 RAET1L

2.37e-09516448982867
Pubmed

NKG2D ligand overexpression in lupus nephritis correlates with increased NK cell activity and differentiation in kidneys but not in the periphery.

RAE1 RAET1G ULBP2 RAET1L

1.65e-087164425583577
Pubmed

Human anaplastic thyroid carcinoma cells are sensitive to NK cell-mediated lysis via ULBP2/5/6 and chemoattract NK cells.

RAET1G ULBP2 RAET1L

1.03e-073164325212604
Pubmed

Direct interaction of the mouse cytomegalovirus m152/gp40 immunoevasin with RAE-1 isoforms.

RAET1G ULBP2 RAET1L

4.10e-074164320166740
Pubmed

Lysyl oxidases: a novel multifunctional amine oxidase family.

LOX LOXL1 LOXL3

4.10e-074164311642359
Pubmed

Differential expression of the LOX family genes in human colorectal adenocarcinomas.

LOX LOXL1 LOXL3

4.10e-074164319724858
Pubmed

Isolation and characterization of retinoic acid-inducible cDNA clones in F9 cells: a novel cDNA family encodes cell surface proteins sharing partial homology with MHC class I molecules.

RAET1G ULBP2 RAET1L

4.10e-07416438882725
Pubmed

Cutting edge: tumor rejection mediated by NKG2D receptor-ligand interaction is dependent upon perforin.

RAET1G ULBP2 RAET1L

4.10e-074164312421908
Pubmed

NKG2D-mediated natural killer cell protection against cytomegalovirus is impaired by viral gp40 modulation of retinoic acid early inducible 1 gene molecules.

RAET1G ULBP2 RAET1L

4.10e-074164312756263
Pubmed

Murine NKG2D ligands: "double, double toil and trouble".

RAET1G ULBP2 RAET1L

4.10e-074164319081632
Pubmed

MULT1E/mIL-12: a novel bifunctional protein for natural killer cell activation.

RAET1G ULBP2 RAET1L

1.02e-065164324572784
Pubmed

Systematic perturbations of SETD2, NSD1, NSD2, NSD3, and ASH1L reveal their distinct contributions to H3K36 methylation.

NSD2 NSD3 SETD2

1.02e-065164339390582
Pubmed

Common polymorphisms in human lysyl oxidase genes are not associated with the adolescent idiopathic scoliosis phenotype.

LOX LOXL1 LOXL3

1.02e-065164321740577
Pubmed

Crystal structures of RAE-1beta and its complex with the activating immunoreceptor NKG2D.

RAET1G ULBP2 RAET1L

2.04e-066164311825567
Pubmed

Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice.

RAET1G ULBP2 RAET1L

2.04e-066164310894171
Pubmed

Ligands for murine NKG2D display heterogeneous binding behavior.

RAET1G ULBP2 RAET1L

2.04e-066164311857333
Pubmed

Single nucleotide polymorphism analysis of the NKG2D ligand cluster on the long arm of chromosome 6: Extensive polymorphisms and evidence of diversity between human populations.

RAET1G ULBP2 RAET1L

2.04e-066164320219610
Pubmed

The NKG2D ligands RAE-1δ and RAE-1ε differ with respect to their receptor affinity, expression profiles and transcriptional regulation.

RAET1G ULBP2 RAET1L

2.04e-066164320976056
Pubmed

Polymorphisms of NKG2D ligands: diverse RAET1/ULBP genes in northeastern Thais.

RAET1G ULBP2 RAET1L

2.04e-066164319688209
Pubmed

The herpesviral Fc receptor fcr-1 down-regulates the NKG2D ligands MULT-1 and H60.

RAET1G ULBP2 RAET1L

3.55e-067164316831899
Pubmed

Stress-regulated targeting of the NKG2D ligand Mult1 by a membrane-associated RING-CH family E3 ligase.

RAET1G ULBP2 RAET1L

3.55e-067164320870941
Pubmed

Critical role of the NKG2D receptor for NK cell-mediated control and immune escape of B-cell lymphoma.

RAET1G ULBP2 RAET1L

3.55e-067164326151313
Pubmed

NKG2D and Its Ligand MULT1 Contribute to Disease Progression in a Mouse Model of Multiple Sclerosis.

RAET1G ULBP2 RAET1L

3.55e-067164330787931
Pubmed

Cutting edge: murine UL16-binding protein-like transcript 1: a newly described transcript encoding a high-affinity ligand for murine NKG2D.

RAET1G ULBP2 RAET1L

3.55e-067164312370332
Pubmed

DRAGON, a bone morphogenetic protein co-receptor.

RGMB ACVR1 ACVR2A

5.67e-068164315671031
Pubmed

A novel ligand for the NKG2D receptor activates NK cells and macrophages and induces tumor immunity.

RAET1G ULBP2 RAET1L

5.67e-068164312645935
Pubmed

Lysyl oxidase (lox) gene deficiency affects osteoblastic phenotype.

LOX LOXL1 LOXL3

5.67e-068164319458888
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

RMND5A RAE1 SRP72 CHD7 TRIM33 SETD2 MDN1 LOX ANAPC4

8.44e-06282164923667531
Pubmed

Localized LoxL3-Dependent Fibronectin Oxidation Regulates Myofiber Stretch and Integrin-Mediated Adhesion.

LOX LOXL1 LOXL3

8.47e-069164326954549
Pubmed

Cutting edge: Toll-like receptor signaling in macrophages induces ligands for the NKG2D receptor.

RAET1G ULBP2 RAET1L

8.47e-069164314764662
Pubmed

Gut microbiota regulates NKG2D ligand expression on intestinal epithelial cells.

RAET1G ULBP2 RAET1L

8.47e-069164323136011
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

EPPK1 RAE1 DYNC2H1 SMCHD1 CHD7 RNF17 TYRO3 SYNE2 NAT10 HELZ

8.50e-063581641032460013
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SHROOM3 NSD2 SMCHD1 AGAP11 ECPAS NCAPH TRIM33 SULF2 SULF1 MRC2 NAT10 MED23

8.76e-065291641214621295
Pubmed

TGF-beta1 induces the different expressions of lysyl oxidases and matrix metalloproteinases in anterior cruciate ligament and medial collateral ligament fibroblasts after mechanical injury.

LOX LOXL1 LOXL3

1.21e-0510164323357697
Pubmed

A cluster of ten novel MHC class I related genes on human chromosome 6q24.2-q25.3.

RAET1G ULBP2 RAET1L

1.21e-0510164311827464
Pubmed

Cell Surface Downregulation of NK Cell Ligands by Patient-Derived HIV-1 Vpu and Nef Alleles.

RAET1G ULBP2 RAET1L

1.65e-0511164326656785
Pubmed

Heparan sulfate 6-O-endosulfatases: discrete in vivo activities and functional co-operativity.

SULF2 SULF1

2.21e-052164216901266
Pubmed

Comparative immunocytochemical localization of lysyl oxidase (LOX) and the lysyl oxidase-like (LOXL) proteins: changes in the expression of LOXL during development and growth of mouse tissues.

LOX LOXL1

2.21e-052164215609098
Pubmed

The prostate-associated lymphoid tissue (PALT) is linked to the expression of homing chemokines CXCL13 and CCL21.

CXCL13 CCL21

2.21e-052164217474076
Pubmed

Inhibition of Lysyl Oxidase and Lysyl Oxidase-Like Enzymes Has Tumour-Promoting and Tumour-Suppressing Roles in Experimental Prostate Cancer.

LOX LOXL1

2.21e-052164226804196
Pubmed

HSulf-1 and HSulf-2 are potent inhibitors of myeloma tumor growth in vivo.

SULF2 SULF1

2.21e-052164216192265
Pubmed

Epithelial Deletion of Sulf2 Exacerbates Bleomycin-Induced Lung Injury, Inflammation, and Mortality.

SULF2 SULF1

2.21e-052164228657777
Pubmed

SULF1/SULF2 splice variants differentially regulate pancreatic tumour growth progression.

SULF2 SULF1

2.21e-052164224726914
Pubmed

Ischemia-reperfusion of the murine testis stimulates the expression of proinflammatory cytokines and activation of c-jun N-terminal kinase in a pathway to E-selectin expression.

SELE MAPK8

2.21e-052164212620934
Pubmed

Differential involvement of the extracellular 6-O-endosulfatases Sulf1 and Sulf2 in brain development and neuronal and behavioural plasticity.

SULF2 SULF1

2.21e-052164220394677
Pubmed

SULFs in human neoplasia: implication as progression and prognosis factors.

SULF2 SULF1

2.21e-052164221599997
Pubmed

Characterization of a novel member of the macrophage mannose receptor type C lectin family.

MBL2 MRC2

2.21e-05216428702911
Pubmed

Short SULF1/SULF2 splice variants predominate in mammary tumours with a potential to facilitate receptor tyrosine kinase-mediated cell signalling.

SULF2 SULF1

2.21e-052164227294358
Pubmed

Extracellular sulfatases support cartilage homeostasis by regulating BMP and FGF signaling pathways.

SULF2 SULF1

2.21e-052164220479257
Pubmed

RAP80 and RNF8, key players in the recruitment of repair proteins to DNA damage sites.

UIMC1 RNF8

2.21e-052164218550271
Pubmed

Sulf1 and Sulf2 Differentially Modulate Heparan Sulfate Proteoglycan Sulfation during Postnatal Cerebellum Development: Evidence for Neuroprotective and Neurite Outgrowth Promoting Functions.

SULF2 SULF1

2.21e-052164226448642
Pubmed

Diffusion magnetic resonance tractography-based evaluation of commissural fiber abnormalities in a heparan sulfate endosulfatase-deficient mouse brain.

SULF2 SULF1

2.21e-052164235131262
Pubmed

CXCL13 and CCL21 are expressed in ectopic lymphoid follicles in cutaneous lymphoproliferative disorders.

CXCL13 CCL21

2.21e-052164217495955
Pubmed

Association of CXCL13 and CCL21 expression with the progressive organization of lymphoid-like structures in Sjögren's syndrome.

CXCL13 CCL21

2.21e-052164215934082
Pubmed

Expression of Heparan Sulfate Endosulfatases in the Adult Mouse Brain: Co-expression of Sulf1 and Dopamine D1/D2 Receptors.

SULF2 SULF1

2.21e-052164234489650
Pubmed

Sulfs are regulators of growth factor signaling for satellite cell differentiation and muscle regeneration.

SULF2 SULF1

2.21e-052164217920055
Pubmed

Cloning and characterization of two extracellular heparin-degrading endosulfatases in mice and humans.

SULF2 SULF1

2.21e-052164212368295
Pubmed

Overexpression of Sulf2 in idiopathic pulmonary fibrosis.

SULF2 SULF1

2.21e-052164223418199
Pubmed

Regulation of fractone heparan sulfate composition in young and aged subventricular zone neurogenic niches.

SULF2 SULF1

2.21e-052164234324645
Pubmed

Sulf loss influences N-, 2-O-, and 6-O-sulfation of multiple heparan sulfate proteoglycans and modulates fibroblast growth factor signaling.

SULF2 SULF1

2.21e-052164218687675
Pubmed

Loss of endothelial sulfatase-1 after experimental sepsis attenuates subsequent pulmonary inflammatory responses.

SULF2 SULF1

2.21e-052164231461325
Pubmed

Functional consequences of the subdomain organization of the sulfs.

SULF2 SULF1

2.21e-052164219520866
Pubmed

The SULFs, extracellular sulfatases for heparan sulfate, promote the migration of corneal epithelial cells during wound repair.

SULF2 SULF1

2.21e-052164223950901
Pubmed

Crosstalk of lysyl oxidase-like 1 and lysyl oxidase prolongs their half-lives and regulates liver fibrosis through Notch signal.

LOX LOXL1

2.21e-052164238466882
Pubmed

Association of E-selectin gene polymorphism and serum PAPP-A with carotid atherosclerosis in end-stage renal disease.

SELE PAPPA

2.21e-052164224151105
Pubmed

Activin A and activin receptors in the human thyroid: a link to the female predominance of goiter?

ACVR1 ACVR2A

2.21e-052164211069203
Pubmed

Endosulfatases SULF1 and SULF2 limit Chlamydia muridarum infection.

SULF2 SULF1

2.21e-052164223480519
Pubmed

Expression of novel extracellular sulfatases Sulf-1 and Sulf-2 in normal and osteoarthritic articular cartilage.

SULF2 SULF1

2.21e-052164218507859
Pubmed

Neuroprotective Effects of the Absence of JNK1 or JNK3 Isoforms on Kainic Acid-Induced Temporal Lobe Epilepsy-Like Symptoms.

MAPK8 MAPK10

2.21e-052164228664455
Pubmed

Heparan sulfate 6-O-endosulfatases, Sulf1 and Sulf2, regulate glomerular integrity by modulating growth factor signaling.

SULF2 SULF1

2.21e-052164226764203
Pubmed

Targeting H3K36 methyltransferases NSDs: a promising strategy for tumor targeted therapy.

NSD2 NSD3

2.21e-052164234083510
Pubmed

Genetic variability in complement activation modulates the systemic inflammatory response syndrome in children.

CFH MBL2

2.21e-052164220351616
Pubmed

SULF1/SULF2 reactivation during liver damage and tumour growth.

SULF2 SULF1

2.21e-052164227013228
Pubmed

c-Jun N-terminal kinase induces axonal degeneration and limits motor recovery after spinal cord injury in mice.

MAPK8 MAPK10

2.21e-052164221824499
Pubmed

Nitric oxide signaling modulates synaptic transmission during early postnatal development.

GAD2 NOS1

2.21e-052164221282319
Pubmed

Heparan Sulfate-Editing Extracellular Sulfatases Enhance VEGF Bioavailability for Ischemic Heart Repair.

SULF2 SULF1

2.21e-052164231434553
Pubmed

Predictive significance of CCL21 and CXCL13 levels in the minor salivary glands of patients with Sjögren's syndrome.

CXCL13 CCL21

2.21e-052164227782867
Pubmed

Multi-tasking Sulf1/Sulf2 enzymes do not only facilitate extracellular cell signalling but also participate in cell cycle related nuclear events.

SULF2 SULF1

2.21e-052164229360432
Pubmed

ALDH1L2 is the mitochondrial homolog of 10-formyltetrahydrofolate dehydrogenase.

ALDH1L1 ALDH1L2

2.21e-052164220498374
Pubmed

A new gene with sequence and structural similarity to the gene encoding human lysyl oxidase.

LOX LOXL1

2.21e-05216427706256
Pubmed

Lysyl oxidase: properties, specificity, and biological roles inside and outside of the cell.

LOX LOXL1

2.21e-052164212577300
Pubmed

Enhanced tumorigenic potential of colorectal cancer cells by extracellular sulfatases.

SULF2 SULF1

2.21e-052164225477293
Pubmed

Organ-specific sulfation patterns of heparan sulfate generated by extracellular sulfatases Sulf1 and Sulf2 in mice.

SULF2 SULF1

2.21e-052164222298771
Pubmed

Abnormal Pyramidal Decussation and Bilateral Projection of the Corticospinal Tract Axons in Mice Lacking the Heparan Sulfate Endosulfatases, Sulf1 and Sulf2.

SULF2 SULF1

2.21e-052164232038163
Pubmed

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.

CFH HSPG2 GALNT2 LOX LOXL1 PAPPA LOXL3 BMPER

2.50e-05248164824006456
Pubmed

Absence of TGFbeta signaling in embryonic vascular smooth muscle leads to reduced lysyl oxidase expression, impaired elastogenesis, and aneurysm.

ACVR1 LOX LOXL1

2.84e-0513164319165826
Pubmed

New genetic associations detected in a host response study to hepatitis B vaccine.

CFH FNDC3B SUSD4 AOAH MBL2 DNER CXCL13 F13B JAG1 SYNE2 ULBP2 RAET1L HAL LY75

3.93e-058241641420237496
Pubmed

Loss of Lysyl Oxidase-like 3 Attenuates Embryonic Lung Development in Mice.

LOX LOXL1 LOXL3

4.49e-0515164327645581
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

HSPG2 COL6A3 DOCK11 ZGRF1 SMCHD1 PRAMEF20 CHD7 MDN1 OGDHL

6.10e-05363164914691545
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

SHROOM3 EPPK1 DYNC2H1 SMCHD1 ECPAS RNF17 NCAPH TRIM33 CASP12 SETD2 SYNE2 NAT10 MED23

6.45e-057541641335906200
Pubmed

JNK Isoforms Are Involved in the Control of Adult Hippocampal Neurogenesis in Mice, Both in Physiological Conditions and in an Experimental Model of Temporal Lobe Epilepsy.

MAPK8 MAPK10

6.61e-053164230685843
Pubmed

Acyl carrier protein-specific 4'-phosphopantetheinyl transferase activates 10-formyltetrahydrofolate dehydrogenase.

ALDH1L1 ALDH1L2

6.61e-053164219933275
Pubmed

The NSD family of protein methyltransferases in human cancer.

NSD2 NSD3

6.61e-053164225942451
Pubmed

The Pro-regions of lysyl oxidase and lysyl oxidase-like 1 are required for deposition onto elastic fibers.

LOX LOXL1

6.61e-053164216251195
Pubmed

Synovial lymphoid neogenetic factors in Behçet's synovitis: do they play a role in self-limiting and subacute course of arthritis?

CXCL13 CCL21

6.61e-053164217949547
Pubmed

JNK1 is required to preserve cardiac function in the early response to pressure overload.

MAPK8 MAPK10

6.61e-053164216579967
Pubmed

Novel cardiovascular biomarkers in women with a history of early preeclampsia.

SELE PAPPA

6.61e-053164225238218
Pubmed

WT1-dependent sulfatase expression maintains the normal glomerular filtration barrier.

SULF2 SULF1

6.61e-053164221719793
Pubmed

Specific pathophysiological functions of JNK isoforms in the brain.

MAPK8 MAPK10

6.61e-053164215673436
Pubmed

Elevated expression levels of lysyl oxidases protect against aortic aneurysm progression in Marfan syndrome.

LOX LOXL1

6.61e-053164225988230
Cytoband2q24

ABCB11 TBR1 LY75

7.23e-061116432q24
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

SELE CFH SUSD4 CR1L CSMD3 F13B PAPPA SEZ6L

1.29e-095710581179
GeneFamilyFibronectin type III domain containing

FNDC3B TRIM42 OBSCN FSD2 TYRO3 USH2A SORL1

4.10e-051601057555
GeneFamilyEF-hand domain containing|Plakins

EPPK1 PPL

9.14e-0481052939
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

NSD2 NSD3 SETD2

9.99e-04341053487
GeneFamilyUbiquitin conjugating enzymes E2

UBE2L6 UBE2L3 UBE2L5

1.73e-03411053102
GeneFamilyUPF1 like RNA helicases

ZGRF1 HELZ

1.78e-031110521169
GeneFamilyPHD finger proteins

NSD2 SP110 NSD3 TRIM33

1.87e-0390105488
GeneFamilyMitogen-activated protein kinases

MAPK8 MAPK10

2.50e-03131052651
GeneFamilyTubulin tyrosine ligase family

TTL TTLL10

2.90e-03141052779
GeneFamilyEndogenous ligands|Minor histocompatibility antigens

TRIM42 SP110 LY75

3.24e-03511053870
GeneFamilyWD repeat domain containing

RAE1 WDR4 NBEAL1 KATNB1 THOC3 FBXW7

4.26e-032621056362
GeneFamilySulfatases

SULF2 SULF1

4.81e-03181052410
GeneFamilyAldehyde dehydrogenases

ALDH1L1 ALDH1L2

5.36e-03191052398
GeneFamilyPWWP domain containing

NSD2 NSD3

7.15e-032210521147
CoexpressionZENG_GU_ICB_CONTROL_METAGENE_14_PRECICTIVE_ICB_RESPONSE

CFH RAET1G CSMD3 CASP12 LOX ULBP2 RAET1L PARP9 LY75

4.17e-061981629MM17083
CoexpressionNABA_ECM_REGULATORS

ADAMTSL1 ST14 F13B SULF2 SULF1 LOX LOXL1 PAPPA LOXL3

1.83e-052381629M3468
CoexpressionNABA_MATRISOME

HSPG2 COL6A3 ADAMTSL1 MBL2 TECTB CXCL13 ST14 F13B CBLN4 SULF2 SULF1 LOX LOXL1 PAPPA LOXL3 BMPER HCFC2 CCL21 USH2A

2.05e-05102616219M5889
CoexpressionNABA_ECM_REGULATORS

ADAMTSL1 ST14 F13B SULF2 SULF1 LOX LOXL1 PAPPA LOXL3

2.08e-052421629MM17062
CoexpressionGSE2197_CPG_DNA_VS_UNTREATED_IN_DC_UP

MORC1 TCAF2 ACP2 IFITM10 C4orf54 CBLN4 UBE2L3 KLHL4

3.62e-052001628M4393
ToppCellfacs-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH HSPG2 COL6A3 ADAMTSL1 TMPRSS6 DNER SULF2 SULF1 LOX LOXL1 LOXL3

1.49e-1019216411a2c31390da4962bda9a936470b0b68fa1f5d47d1
ToppCellfacs-Lung-nan-3m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH HSPG2 COL6A3 ADAMTSL1 TMPRSS6 DNER SULF2 SULF1 LOX LOXL1 LOXL3

1.49e-1019216411eeab1cef7c36ae824381952c5b2c982368c379fd
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZAN RSPH6A CSMD3 PKHD1L1 SFMBT2 PKHD1 TENM1 ABCB11 USH2A

9.55e-091621649bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZAN TMPRSS6 CXCL13 RNF17 CSMD3 PKHD1L1 NALCN PKHD1 USH2A

1.38e-08169164912bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellRV-01._Fibroblast_I|RV / Chamber and Cluster_Paper

CFH COL6A3 RARRES1 DYNC2H1 XYLT1 MRC2 PAPPA BMPER MAPK10

4.16e-081921649356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCelldroplet-Fat-Scat-18m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A3 ADAMTSL1 TMPRSS6 CXCL13 MRC2 LOX LOXL1 LOXL3 BMPER

4.35e-081931649316ebdf15f75d88c348f909b643fcd315364ca84
ToppCelldroplet-Fat-Scat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A3 ADAMTSL1 TMPRSS6 CXCL13 MRC2 LOX LOXL1 LOXL3 BMPER

4.35e-0819316491afdd3f7d703f4204a2cbfe40e135ac7b09213f7
ToppCellLV-01._Fibroblast_I|LV / Chamber and Cluster_Paper

CFH FNDC3B COL6A3 DYNC2H1 SULF1 MRC2 PAPPA BMPER MAPK10

4.35e-081931649dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCelldroplet-Fat-Scat-18m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A3 ADAMTSL1 TMPRSS6 CXCL13 MRC2 LOX LOXL1 LOXL3 BMPER

4.35e-0819316498dc6db335678f3a5cfd36026ad811fed8d9cb4bc
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CFH COL6A3 ADAMTSL1 XYLT1 GNA14 NALCN SULF1 MRC2 EEPD1

4.55e-081941649e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCellASK428-Epithelial-Transformed_epithelium|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

CFH RARRES1 DOCK11 PKHD1L1 SULF2 SULF1 EEPD1 SSX2IP PAPPA

4.76e-081951649c750602c765a51075ba6ede78e3ba80b62374481
ToppCellmetastatic_Brain-Fibroblasts-FB-like_cells|Fibroblasts / Location, Cell class and cell subclass

CFH HSPG2 COL6A3 RARRES1 SULF2 SULF1 LOX LOXL1 PAPPA

5.91e-082001649f62833c63f9c6a94b6cc2ba8e2f960e67f093f48
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_1|E16.5-samps / Age Group, Lineage, Cell class and subclass

CFH GAD2 COL6A3 FSD2 MRC2 LOX LOXL1 EEPD1

1.69e-071631648f1ec2625b52664308968b01d8e0275e1e0751480
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAMTSL1 SUSD4 FAM217A PKHD1L1 CLHC1 PAPPA CCL21 KLHL4

1.77e-0716416484cfc9f92e49f86d3639e018b35b6a60dc62f494a
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAMTSL1 SUSD4 FAM217A PKHD1L1 CLHC1 PAPPA CCL21 KLHL4

1.77e-0716416487a8e5ef52a8fd2877d59ef0696af8a7af90bbed6
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAMTSL1 SUSD4 FAM217A PKHD1L1 CLHC1 PAPPA CCL21 KLHL4

1.77e-0716416485e5bd81414ea2d64f73cdef19a0a78c17bec8c18
ToppCellPND10-Endothelial-Endothelial_lymphatic|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAMTSL1 SUSD4 FAM217A PKHD1L1 CLHC1 PAPPA CCL21 KLHL4

1.77e-071641648f13b8d9b7f42193f333d9a77571a1dde6bbb48d8
ToppCell356C-Fibroblasts-Fibroblast-H-|356C / Donor, Lineage, Cell class and subclass (all cells)

COL6A3 RARRES1 ACVR2A TYRO3 GNA14 LOX LOXL1 PAPPA

2.13e-071681648b5d74500bdac0d680ce7eb7afa0b867b8d85e6a4
ToppCell356C-Fibroblasts-Fibroblast-H|356C / Donor, Lineage, Cell class and subclass (all cells)

COL6A3 RARRES1 ACVR2A TYRO3 GNA14 LOX LOXL1 PAPPA

2.13e-071681648838ce47d4958ba12047882f97925eddd02f081c7
ToppCell390C-Fibroblasts-Fibroblast-G|390C / Donor, Lineage, Cell class and subclass (all cells)

CFH COL6A3 RARRES1 NALCN MRC2 ALDH1L2 LOXL1 PAPPA

3.60e-071801648137fc14859c89e1ecd98bee388bb58c04b835847
ToppCell390C-Fibroblasts-Fibroblast-G-|390C / Donor, Lineage, Cell class and subclass (all cells)

CFH COL6A3 RARRES1 NALCN MRC2 ALDH1L2 LOXL1 PAPPA

3.60e-071801648cd6790de050151fedfa2c5ea6ad58b72665414b2
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-5_PVALB_TRIM67|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD2 DOCK11 DNER SFMBT2 KCNJ5 PKHD1 TENM1 NOS1

4.26e-0718416487f6c8912677764d438ab0555faca344d74c2f483
ToppCelldroplet-Kidney-nan-21m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH COL6A3 ADAMTSL1 ACTN3 PROKR1 SULF1 MRC2 LOXL1

4.26e-0718416483bffadb0cb2e0d825bdb6cfc5d23f5436cbc3efd
ToppCelldroplet-Kidney-nan-21m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH COL6A3 ADAMTSL1 ACTN3 PROKR1 SULF1 MRC2 LOXL1

4.44e-07185164833cc0e9d8b54cb7408b51235f2a70e044ebae04d
ToppCelldroplet-Kidney-nan-21m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH COL6A3 ADAMTSL1 ACTN3 PROKR1 SULF1 MRC2 LOXL1

4.44e-0718516489954fc85b183c1cc45c3c24e3dadc7984ee6f649
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CFH COL6A3 SHROOM3 MRC2 LOX LOXL1 EEPD1 BMPER

4.62e-07186164888e6246172d816806a498a5c1f38e699f2f5d7c2
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD2 DOCK11 DNER KCNJ5 PKHD1 TENM1 PAPPA NOS1

4.81e-07187164885f1678338a47d91e296f0620d4887f057eb7e70
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH ADAMTSL1 PKHD1L1 MRC2 LOX LOXL1 PAPPA BMPER

4.81e-0718716484e553721fa5598cb211f44e3226280b7e6885484
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH ADAMTSL1 PKHD1L1 MRC2 LOX LOXL1 PAPPA BMPER

4.81e-071871648d36e7fc6125e7a4310499365022d38f34b757a73
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH ADAMTSL1 PKHD1L1 MRC2 LOX LOXL1 PAPPA BMPER

4.81e-071871648827eae63fabf6892a82ce7779b5f395958d3d628
ToppCellCOVID-19-lung-Vein_EC|lung / Disease (COVID-19 only), tissue and cell type

SELE HSPG2 ADAMTSL1 PKHD1L1 PLEKHG1 SULF2 GNA14 NOS1

5.01e-071881648d582b76fc2faac526c9bf97503041129e1a6a211
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD2 DOCK11 DNER SULF1 TENM1 OSBPL10 PAPPA NOS1

5.43e-071901648d19bc44310c53726e2f5f6a2bd377bbbf1d1983f
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DNER CXCL13 CBLN4 GNA14 SULF1 LOX PAPPA KLHL4

5.43e-0719016484f775ee24b14733f06ae40b45f2dc1a0f0df0705
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CFH COL6A3 ADAMTSL1 XYLT1 GNA14 NALCN MRC2 EEPD1

5.65e-071911648a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFH COL6A3 GALNT2 RARRES1 SFMBT2 MRC2 PAPPA BMPER

5.65e-07191164808720998aa55131d7377c4c67c4c935865bd7d79
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CFH COL6A3 ADAMTSL1 XYLT1 GNA14 NALCN MRC2 EEPD1

5.65e-0719116488f6d592edc32fdb901af30501d4360512334e8c2
ToppCelldroplet-Kidney-nan-18m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH COL6A3 ADAMTSL1 CASP12 MRC2 LOX LOXL1 LOXL3

5.88e-07192164838d7a24ae205ef91ed2e0f402d8022f2a9cdb243
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 COL6A3 ADAMTSL1 SULF1 MRC2 LOX LOXL1 PAPPA

5.88e-0719216488937a59f6bbe07f671bdabbd3707dc9c17a14cd9
ToppCelldroplet-Kidney-nan-18m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH COL6A3 ADAMTSL1 CASP12 MRC2 LOX LOXL1 LOXL3

5.88e-07192164804d155897ed075c359933080e36a4ab2150b6e9f
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 COL6A3 ADAMTSL1 SULF1 MRC2 LOX LOXL1 PAPPA

5.88e-071921648e4a7f2673f801b008ca67291db2fb2b9fd2955b8
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 COL6A3 ADAMTSL1 SULF1 MRC2 LOX LOXL1 PAPPA

5.88e-071921648ac1477433704573f95111eee6263b93668d2845e
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFH HSPG2 COL6A3 TMPRSS6 SULF2 LOX LOXL1 LOXL3

5.88e-07192164832acd89617934016cd135d2cc797e8e79ae1b37f
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

FNDC3B SHROOM3 SYNE2 PKHD1 OSBPL10 MAPK8 MAPK10 VPS13B

5.88e-071921648e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CFH COL6A3 RARRES1 SULF1 MRC2 LOX LOXL1 CCL21

6.11e-071931648dc8e62df6121ee99b156aca6b1b3ae555739b6f2
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 COL6A3 TMPRSS6 CXCL13 MRC2 LOX LOXL1 BMPER

6.11e-07193164849600db68ed65cafc67bd45a285b364e4f5f88af
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DOCK11 DNER CBLN4 GNA14 SULF1 LOX PAPPA KLHL4

6.11e-071931648adc9fc94f9ec686a417d08c0b8b7b7ab687afec0
ToppCellRV-10._Endothelium_II|World / Chamber and Cluster_Paper

HSPG2 ADAMTSL1 PKHD1L1 PLEKHG1 SULF2 GNA14 SYNE2 BMPER

6.11e-0719316482531266bc57339d4e2b22a88817008e32b8c1598
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 COL6A3 TMPRSS6 CXCL13 MRC2 LOX LOXL1 BMPER

6.11e-07193164845b5cab4dfeb0ed3b13631db5963740a792b810f
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CFH COL6A3 RARRES1 SULF1 MRC2 LOX LOXL1 CCL21

6.11e-071931648e2ee077fd381bd906e6b4329f22e7d106e422a7f
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CFH COL6A3 RARRES1 SULF1 MRC2 LOX LOXL1 CCL21

6.36e-07194164829f83cdd63314fff41258937d70b881a5503bfcc
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CFH COL6A3 RARRES1 SULF1 MRC2 LOX LOXL1 CCL21

6.36e-071941648d3db241ea316bbcde6d16618193b474591ad5ce4
ToppCellCOVID-19-Heart-Fib_1|Heart / Disease (COVID-19 only), tissue and cell type

CFH FNDC3B COL6A3 RARRES1 DYNC2H1 SULF1 MRC2 MAPK10

6.61e-071951648f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCellIPF-Stromal-Fibroblast|IPF / Disease state, Lineage and Cell class

CFH COL6A3 ADAMTSL1 RARRES1 SULF1 MRC2 LOX LOXL1

6.87e-071961648f7ae604ba32b322d86d68b2b54892e7c6ab06c49
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CFH COL6A3 ADAMTSL1 RARRES1 GNA14 NALCN SULF1 MRC2

6.87e-0719616482b36b9a40fe415917afccff99ad9c3474e087d0d
ToppCelldistal-mesenchymal-Adventitial_Fibroblast-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CFH COL6A3 RARRES1 DNER MRC2 LOX LOXL1 PAPPA

7.41e-071981648bfd720e2dae3b6b3dc2bf8b2096c554fd456e756
ToppCelldistal-1-mesenchymal-Mesothelial|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CFH RARRES1 ALDH1L1 SULF1 LOX LOXL1 PAPPA KLHL4

7.70e-0719916488dd5b411d2f1626830b77a1616cc3fb67dc59338
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_adventitial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFH COL6A3 RARRES1 SULF1 MRC2 LOX LOXL1 PAPPA

8.00e-0720016486b48ddde83bc6c941d557844aa214d4d2c8e736d
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFH COL6A3 SULF1 MRC2 ALDH1L2 LOX LOXL1 PAPPA

8.00e-07200164854806080b5e97859ee6a4a9b4f19e22021c218f5
ToppCellFetal_29-31_weeks-Mesenchymal-chondrocyte-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

GALNT2 HTR3C ALDH1L1 SFMBT2 MRC2 PAPPA CCL21

1.63e-06153164765641cc82883716dba0fefb749a30174a63f4da5
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF268 CXCL13 AGAP11 THOC3 PAPPA RND2 BMPER

1.70e-061541647cd99428c282d566b5dbd31fd5a0371b7ffe9ffa2
ToppCellfacs-Spleen-nan-3m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNT2 AOAH IFITM10 ACSS2 TYRO3 SULF2 PEAK1

2.59e-061641647a187bd5beca017ef657ef07c006e7f94ea3b911b
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CXCL13 CASP12 SULF2 SULF1 LOX LOXL1 ENO2

2.69e-0616516474e13fccd32029e2879e85f8966e582a46c09e4aa
ToppCellLV-11._Adipocyte|World / Chamber and Cluster_Paper

GLYAT DOCK11 ALDH1L1 ACSS2 TYRO3 EEPD1 MAPK10

2.80e-0616616477e5852891714465c6228c9f955fd511ec79d0e02
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFH ADAMTSL1 PKHD1L1 PPL SULF1 SYNE2 HAL

2.92e-061671647c042d6cdddd0e1ddef1e3ac6f4fe23151127b0f2
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFH ADAMTSL1 PKHD1L1 PPL SULF1 SYNE2 HAL

2.92e-061671647351f8de1fbdf742ac74f9099b254d515ab539bb2
ToppCellAdult-Mesenchymal-myofibroblast_cell|Adult / Lineage, Cell type, age group and donor

CFH COL6A3 RARRES1 HTR3C NALCN PAPPA BMPER

2.92e-061671647d584a8548a5317bd9686b3be8246ae6ed568796b
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Pleural_Mac|Myeloid_cells / Location, Cell class and cell subclass

WDR4 OBSCN CXCL13 MAU2 ECPAS CR1L EEPD1

3.04e-0616816478697b40b2ec2cce68ef3beb4792eb3eff29be053
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CFH COL6A3 ADAMTSL1 XYLT1 GNA14 NALCN EEPD1

3.04e-061681647d19a115365c5415e51c039718d7669de788fcf33
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFH COL6A3 DNER OBSCN CASP12 LOXL1 SPINDOC

3.04e-061681647d2b91f2adc95dcfa623f8d7ca2df1c6f884da988
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CFH COL6A3 ADAMTSL1 OBSCN CSMD3 PAPPA BMPER

3.83e-061741647f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH COL6A3 NALCN LOX PAPPA BMPER PEAK1

3.98e-0617516471799a7be623dc3bf53ba580a7c47d2619969d708
ToppCellnormal_Lung-Fibroblasts-Mesothelial_cells|normal_Lung / Location, Cell class and cell subclass

CFH RARRES1 RAET1G SULF1 QPRT OGDHL PAPPA

4.13e-061761647f31d7234053085a82cf9d55aeedd1e04d34789c3
ToppCellP28-Endothelial-lymphatic_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADAMTSL1 SUSD4 FAM217A PKHD1L1 SULF2 CCL21 KLHL4

4.28e-0617716476e330aa3c87fd640526b746a9deb3b2250d2518c
ToppCellP28-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADAMTSL1 SUSD4 FAM217A PKHD1L1 SULF2 CCL21 KLHL4

4.28e-061771647e96a7e4544710aaab8bd2800ecff9667880a8bf4
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SELE HSPG2 ACVR1 PKHD1L1 SULF1 LOX JAG1

4.28e-061771647d68132e145bd413404fdbe215b5dbe520e756e50
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 RARRES1 CBLN4 MRC2 ALDH1L2 UBE2L5 BMPER

4.78e-061801647c2746092ef251e9d5910fe96461afdd0624a24c6
ToppCellCOVID-19-kidney-PCT-S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

GLYAT ALDH1L1 SYNE2 PKHD1 TENM1 OSBPL10 PAPPA

4.78e-061801647358923e4228035a3e90e2957392089219e90dcd7
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 RARRES1 CBLN4 MRC2 ALDH1L2 UBE2L5 BMPER

4.78e-06180164732c6a3886428d82fb4355d987c6d2645f333447b
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFH HSPG2 COL6A3 TYRO3 MRC2 LOXL1 LOXL3

4.78e-06180164739ae8586efd91536e9ac6408d26de7e6d6237c41
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH ADAMTSL1 MRC2 LOX LOXL1 LOXL3 BMPER

4.96e-061811647269b39ac65790061d54eab47a8eeb024403f0348
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFH PKHD1L1 SFMBT2 SULF2 SULF1 KCNJ5 SYNE2

4.96e-061811647330d4322f4c4373f706273c1f4e218b59051b7fd
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH ADAMTSL1 MRC2 LOX LOXL1 LOXL3 BMPER

4.96e-061811647cd4f744b6b64ba6c22ec07afd1d3058a2546909d
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH ADAMTSL1 MRC2 LOX LOXL1 LOXL3 BMPER

4.96e-061811647c8395ae872aa80b3ae1ab7c53e57b3ca15aeb0e2
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFH PKHD1L1 SFMBT2 SULF2 SULF1 KCNJ5 SYNE2

4.96e-0618116473f4d5d79c1286614514b0e8134079d6128a2a23e
ToppCellfacs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH COL6A3 MRC2 LOX LOXL1 BMPER PEAK1

5.15e-061821647c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCellP28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CFH COL6A3 LOX LOXL1 EEPD1 BMPER PEAK1

5.15e-06182164719c5e3a9d9b3728303b682102e276adfe93aa759
ToppCellfacs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH COL6A3 MRC2 LOX LOXL1 BMPER PEAK1

5.15e-061821647dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCelldroplet-Kidney-nan-21m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A3 CXCL13 SULF1 MRC2 KCNJ5 ABCB11 BMPER

5.33e-061831647f55081068213cc1cdb2acad58ff10f6b48b44c72
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZAN OBSCN CSMD3 PKHD1L1 PKHD1 TENM1 USH2A

5.53e-0618416472cbed6462fea2622871bb7e49b0df3d984239281
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SMCHD1 NCAPH SYNE2 TENM1 ENO2 KRBOX5 SORL1

5.53e-061841647bd786db4dc4edae6d5cfc0b69901983dea19f729
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZAN OBSCN CSMD3 PKHD1L1 PKHD1 TENM1 USH2A

5.53e-061841647ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZAN OBSCN CSMD3 PKHD1L1 PKHD1 TENM1 USH2A

5.53e-0618416472b19a8c5f823e00812908b23e66bb4e563278aff
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTSL1 SUSD4 FAM217A PKHD1L1 MDN1 SEZ6L KLHL4

5.73e-061851647bb5a4cf93534b9bcd0923f314c389d571e91e7f8
ToppCellfacs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SUSD4 FSD2 FAM217A PKHD1L1 OSBPL10 CCL21 KLHL4

5.73e-06185164759acaf025353405948dc34ccccf37ec5c08ea903
ToppCellmetastatic_Lymph_Node-Fibroblasts-COL13A1+_matrix_FBs|metastatic_Lymph_Node / Location, Cell class and cell subclass

SELE COL6A3 CXCL13 TYRO3 LOXL1 PAPPA CCL21

6.15e-061871647e04fb35f2f5b120659d06b5ae427ab1ec56d5c36
ToppCellCOVID-19-kidney|COVID-19 / Disease (COVID-19 only), tissue and cell type

GLYAT ALDH1L1 SYNE2 PKHD1 OGDHL PAPPA MAPK10

6.15e-061871647d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFH HSPG2 COL6A3 ADAMTSL1 TMPRSS6 LOXL1 KCNJ5

6.36e-061881647b382d18fb09fb2869f3c151efa71540a7f5ed229
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CFH COL6A3 OBSCN LOX PAPPA BMPER MAPK10

6.36e-061881647997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Igfbp4-Inhibitory_Neuron.Gad1Gad2.Igfbp4.Rgs4_(Striatum,_interneuron)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

C4orf54 PROKR1 GNA14 PKHD1 USH2A

6.49e-06711645b0dbb059a7d05f825da608879b23aeebd6e9e61f
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Igfbp4-Inhibitory_Neuron.Gad1Gad2.Igfbp4.Rgs4_(Striatum,_interneuron)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

C4orf54 PROKR1 GNA14 PKHD1 USH2A

6.49e-06711645149504ce72da0730074ea436fc2034ce8cb585d5
Diseaselevel of UL16-binding protein 6 in blood serum

ULBP2 RAET1L

2.81e-0521572OBA_2043185
DiseaseMalignant neoplasm of breast

FNDC3B RCCD1 DYNC2H1 NSD2 TMPRSS6 OBSCN SHMT1 ACVR1 SP110 SETD2 SULF2 JAG1 SYNE2 TENM1 VPS13B SORL1 FBXW7

6.23e-05107415717C0006142
DiseaseIron-Refractory Iron Deficiency Anemia

TMPRSS6 ACVR1

8.41e-0531572C0085576
Diseasedelta and Notch-like epidermal growth factor-related receptor measurement

CFH DNER

8.41e-0531572EFO_0802458
DiseaseSotos syndrome 1 (implicated_via_orthology)

NSD2 NSD3

8.41e-0531572DOID:0112103 (implicated_via_orthology)
DiseaseColorectal Carcinoma

OMA1 DNAH3 OBSCN HTR3C ALDH1L1 CSMD3 PKHD1 TENM1 ABCB11 TTLL10 ANAPC4 SORL1 FBXW7

1.03e-0470215713C0009402
DiseaseWolf-Hirschhorn syndrome (implicated_via_orthology)

LETM2 NSD2

1.68e-0441572DOID:0050460 (implicated_via_orthology)
Diseasechronic obstructive pulmonary disease, coronary artery disease

DYNC2H1 RSPH6A

1.68e-0441572EFO_0000341, EFO_0001645
Diseasevital capacity

CFH HSPG2 COL6A3 SHROOM3 ADAMTSL1 DNER ZKSCAN2 CHD7 ACTN3 SULF1 MRC2 LOX LOXL1 PARP9 BMPER CCL21 ANAPC4

3.30e-04123615717EFO_0004312
Diseasehemolytic-uremic syndrome (is_implicated_in)

CFH MBL2

4.16e-0461572DOID:12554 (is_implicated_in)
Diseaseglial fibrillary acidic protein measurement

CFH MBL2

4.16e-0461572EFO_0020404
Diseasepulse pressure measurement

CFH LETM2 GLYAT FNDC3B COL6A3 SHROOM3 NBEAL1 DYNC2H1 CR1L NSD3 PLEKHG1 UBE2L3 MRC2 LOXL1 EEPD1 JAG1 ABCB11 SPINDOC

4.57e-04139215718EFO_0005763
Diseaseurate measurement, bone density

TMPRSS6 AOAH DNER SFMBT2 PPL SULF1 ALKBH3 CAMKMT PEAK1 MAPK8 USH2A

5.02e-0461915711EFO_0003923, EFO_0004531
Diseasecadherin-15 measurement

CFH GALNT2

5.80e-0471572EFO_0020211
Diseaseexfoliation syndrome (is_implicated_in)

ACVR1 LOXL1

5.80e-0471572DOID:13641 (is_implicated_in)
DiseaseL-Selectin measurement

SELE SULF2 TENM1

5.95e-04311573EFO_0008202
Diseasenucleotide measurement

GALNT2 SULF1 SYNE2 MAPK10

6.31e-04731574EFO_0010513
Diseaseeosinophil cationic protein measurement

CFH SPATA31C1

7.71e-0481572EFO_0010913
Diseasetyrosine-protein kinase receptor TYRO3 measurement

CFH TYRO3

7.71e-0481572EFO_0020829
DiseaseGalloway Mowat syndrome

WDR4 OSGEP

7.71e-0481572C0795949
Diseaseprogrammed cell death 1 ligand 2 measurement

CFH RIC1

7.71e-0481572EFO_0008268
Diseasecomplement factor H-related protein 5 measurement

CFH F13B SORL1

1.46e-03421573EFO_0008098
Diseasefamilial atrial fibrillation

SELE HSPG2 KCNJ5 SYNE2 SORL1

1.51e-031561575C3468561
DiseasePersistent atrial fibrillation

SELE HSPG2 KCNJ5 SYNE2 SORL1

1.51e-031561575C2585653
DiseaseParoxysmal atrial fibrillation

SELE HSPG2 KCNJ5 SYNE2 SORL1

1.51e-031561575C0235480
Diseasenon-high density lipoprotein cholesterol measurement

OMA1 GALNT2 CHD7 UBE2L3 EEPD1 SYNE2 ABCB11 HELZ CAMKMT UBE2L5 SPINDOC

1.57e-0371315711EFO_0005689
Diseasememory performance

CFH OMA1 FNDC3B IFITM10 CBLN4 SYNE2 ANAPC4 SORL1

1.62e-034091578EFO_0004874
DiseaseAtrial Fibrillation

SELE HSPG2 KCNJ5 SYNE2 SORL1

1.69e-031601575C0004238
Diseaseopioid dependence

CSMD3 SFMBT2 SULF1 PAPPA MAPK8 SPINDOC

1.74e-032371576EFO_0005611
Diseasemultiple sclerosis symptom measurement

ZNF74 CAMKMT SEZ6L

1.90e-03461573EFO_0803536
Diseasehemoglobin A1 measurement

FNDC3B GAD2 TMPRSS6 PLEKHG1 SETD2 JAG1 SYNE2 ABCB11 ANAPC4

1.94e-035201579EFO_0007629
Diseaseobsolete_red blood cell distribution width

FNDC3B GALNT2 RCCD1 TMPRSS6 AOAH SHMT1 MAU2 THOC3 CR1L NSD3 PLEKHG1 TRIM33 UBE2L3 EEPD1 SYNE2 ABCB11

2.28e-03134715716EFO_0005192
Diseaseblood phosphate measurement

HSPG2 ADAMTSL1 FAM178B PARP9 MED23

2.44e-031741575EFO_0010972
Diseaseasthma, body mass index

ACTN3 PIK3C3

2.45e-03141572EFO_0004340, MONDO_0004979
Diseasetriacylglycerol 48:4 measurement

MBL2 SFMBT2

2.45e-03141572EFO_0010407
DiseaseC-C motif chemokine 19 measurement

CFH CCL21

2.45e-03141572EFO_0008047
Diseasemyocardial infarction

FNDC3B COL6A3 SHROOM3 NBEAL1 DYNC2H1 RSPH6A PLEKHG1

2.78e-033501577EFO_0000612
DiseaseMicrosatellite Instability

ACVR2A SETD2

2.82e-03151572C0920269
Diseasecathepsin D measurement

MAU2 IFITM10

2.82e-03151572EFO_0010611
DiseaseReplication Error Phenotype

ACVR2A SETD2

2.82e-03151572C1721098
Diseaseperipheral arterial disease

CSMD3 OSBPL10 MAPK10

3.00e-03541573EFO_0004265
Diseasephospholipids in medium HDL measurement

GALNT2 TECTB UBE2L3

3.17e-03551573EFO_0022295
Diseaseresponse to acetylsalicylate

OMA1 SETD2

3.21e-03161572GO_1903492
DiseaseMuscle hypotonia

NSD2 LSS

3.63e-03171572C0026827
Diseasetotal lipids in medium HDL measurement

GALNT2 TECTB UBE2L3

3.68e-03581573EFO_0022310
Diseasefree cholesterol in medium HDL measurement

GALNT2 TECTB UBE2L3

3.68e-03581573EFO_0022267
Diseaseatrial fibrillation

HSPG2 SULF2 KCNJ5 SYNE2 PAPPA HCFC2 SORL1

3.83e-033711577EFO_0000275
Diseaseandrostenedione measurement, estrone measurement

GALNT2 BMPER

4.07e-03181572EFO_0007970, EFO_0007972
Diseasesyndrome (implicated_via_orthology)

NSD2 NSD3

4.07e-03181572DOID:225 (implicated_via_orthology)
Diseasematrix metalloproteinase 12 measurement

DYNC2H1 CASP12

4.07e-03181572EFO_0010590
Diseaselupus nephritis (is_implicated_in)

CFH MBL2

4.07e-03181572DOID:0080162 (is_implicated_in)
Diseasefree cholesterol in HDL measurement

GALNT2 TECTB UBE2L3

4.24e-03611573EFO_0022264
Diseasephospholipids in HDL measurement

GALNT2 TECTB UBE2L3

4.24e-03611573EFO_0022293
Diseasecarotid artery disease (is_marker_for)

HSPG2 PAPPA

4.53e-03191572DOID:3407 (is_marker_for)
Diseaseangina pectoris

CFH NBEAL1 DYNC2H1 LOXL1

4.54e-031251574EFO_0003913
Diseasetotal lipids in HDL measurement

GALNT2 TECTB UBE2L3

4.65e-03631573EFO_0022307
Diseasecoronary artery disease

OMA1 FNDC3B COL6A3 SHROOM3 GALNT2 NBEAL1 DYNC2H1 ZNF268 RSPH6A PLEKHG1 LOX LOXL1 PKHD1 SEZ6L

4.77e-03119415714EFO_0001645
Diseasearterial stiffness measurement

RSPH6A ACVR2A RIC1

4.86e-03641573EFO_0004517
Diseaseunipolar depression

CFH ADAMTSL1 DYNC2H1 MBL2 CHD7 CSMD3 CLHC1 NALCN PIK3C3 SYNE2 PKHD1 BMPER LY75 NOS1

5.20e-03120615714EFO_0003761
Diseasecholine measurement

GALNT2 SULF2 UBE2L3 ABCB11

5.22e-031301574EFO_0010116
Diseasekeratoconus

FNDC3B LOX PKHD1

5.29e-03661573MONDO_0015486

Protein segments in the cluster

PeptideGeneStartEntry
WQFVVGKRTVPDNQC

CHRM4

171

P08173
GHQVPESVNLTCKQW

C2orf16

396

Q68DN1
QAELCADPKELWVQQ

CCL21

71

O00585
CETQNPKWASLNLGV

AGAP11

346

Q8TF27
NENTGKEVTCLAWRP

ANAPC4

61

Q9UJX5
LIGEKSIVCQENNQW

CSMD3

696

Q7Z407
NNLNCVWKITVPEGA

CSMD3

1961

Q7Z407
GSSVLICQPNGQWDK

CSMD3

2971

Q7Z407
PNQVGGECTNQKWSV

SSX2IP

571

Q9Y2D8
GWCDKIQGSTIPINQ

ALDH1L2

556

Q3SY69
NWEKDRTNQTGVEPC

ACVR2A

36

P27037
QNEVKSVQPGEVCCW

GRM2

506

Q14416
GDWCNRNITAQLPTK

ACVR1

96

Q04771
LEQLCQDVPWKQRTG

ALKBH3

106

Q96Q83
QIPGKACVNNTIVWT

ABCB11

101

O95342
DNPFINWNPKECVGI

HTR3C

96

Q8WXA8
NWNPKECVGINKLTV

HTR3C

101

Q8WXA8
KGPNKIQCVDGEWTT

CFH

666

P08603
KRSCPDVQISWNQGI

ACSS2

271

Q9NR19
NEWEASKCNIVCTQP

DHX29

616

Q7Z478
NGICGTKHWDQEPDV

CASP12

176

Q6UXS9
DNICEAVLKGKWPVN

CHD7

2321

Q9P2D1
TEAIQACKLAQENGW

ENO2

351

P09104
WNLQGCSVEKANNPG

EEPD1

266

Q7L9B9
NWDIKDIINCIGGLN

NBEAL1

861

Q6ZS30
VRCWEVQDSGQTIPK

RAE1

66

P78406
DKQLQVKAVTCGPWN

RCCD1

351

A6NED2
LKCVVPGQAHAQVTW

HSPG2

2846

P98160
WPQDVVDGTCVAVNN

RIC1

246

Q4ADV7
AQIFPQWRKGNTEEC

PARP9

31

Q8IXQ6
VGDQEWIPCVENLSG

KCNJ5

121

P48544
VWRAQPTEGCLKNAQ

MORC1

681

Q86VD1
QDSNCNGIWGVDPKD

AOAH

226

P28039
ENPGTARAWCQVAQK

GAD2

21

Q05329
TCWLQEVPGKPQLEQ

LETM2

81

Q2VYF4
CQWIDITDVKPGNYI

LOXL3

676

P58215
PQVEGKDSLCSVLWN

MDN1

3901

Q9NU22
NPVATVKAGERQWCD

HCFC2

586

Q9Y5Z7
QWNKVIEQLGTPCPE

MAPK10

271

P53779
QEAVCPWESQDGKGL

GPR179

2071

Q6PRD1
CLQKWFEPAQGNPNV

IZUMO1R

206

A6ND01
DQAGQWRIQCVPKEP

MYG1

296

Q9HB07
CQEFLGSPELINWKQ

GLYAT

86

Q6IB77
SVEVCGPALSQQWKF

GALNT2

551

Q10471
NWGKVADLAICNDQL

KATNB1

271

Q9BVA0
IDCQWIDITDVQPGN

LOXL1

516

Q08397
KCFPVVEEQQGLWQS

C1orf109

16

Q9NX04
INCQVAGVPEAEVTW

ADAMTSL1

1306

Q8N6G6
GDNPWTPEQLEQCKL

ECPAS

231

Q5VYK3
GKWTLPPECVENNEN

F13B

381

P05160
EQCQWIRQKFETPGV

OGDHL

216

Q9ULD0
IDQWNKVIEQLGTPC

MAPK8

231

P45983
QECDWEEISVKGPNG

PPL

1691

O60437
IQEHCENKPVIIGWN

PEAK1

91

Q9H792
QNVKGLQNDPEEWVA

FAM236A

16

A0A1B0GUQ0
PNCETLKWTVNGDTR

NSD2

1146

O96028
DWPQENIAGVFNKSC

LSS

686

P48449
VNNSGAICNSWKLDP

MED23

231

Q9ULK4
DCVLLLKNGQWNDVP

MBL2

221

P11226
WKTVDCNDNQPGAIC

LY75

1206

O60449
TQGQWTQQIPVCEAF

SELE

351

P16581
ANVKVECEPSWQPFQ

MRC2

376

Q9UBG0
QLNCQVSWFLPEGSK

QPRT

66

Q15274
EGKWNKQVACEPVDC

PAPPA

1271

Q13219
VAQLWNKPLVGVNHC

OSGEP

96

Q9NPF4
VSQEVPENCQEWIGG

HELZ

321

P42694
NKSIVCVDPQAEWIQ

CXCL13

71

O43927
NTVECFNPVGKIWTV

KLHL4

491

Q9C0H6
EWNEVLNKAGPNASI

NAT10

971

Q9H0A0
PANVQFTEICIQQGW

NOS1

501

P29475
QDIWKEICQAQGKDP

PPP4R3C

91

Q6ZMV5
GPVVQVNTWSCDEQG

PASD1

701

Q8IV76
CQIVGNPTPQVSWEK

OBSCN

31

Q5VST9
VVPKDWQQECQLASG

ACP2

361

P11117
VTNIDVPCGGNQDQW

DYNC2H1

4281

Q8NCM8
EWLAVPCQDAQLTVG

HAL

11

P42357
REGIKVHWEPQQNCA

BMPER

611

Q8N8U9
QCNVDIKWVDGAKPL

DOCK11

796

Q5JSL3
QNQWLAECKDKVIPG

DNAH3

3021

Q8TD57
QNVKGLQNDPEEWVA

FAM236B

16

A0A1B0GV22
LVLNWEEPCNNGSEI

FNDC3B

886

Q53EP0
GNTVIWDNKTPVCDR

CR1L

141

Q2VPA4
DIRKQCDWFQGDQPT

COL6A3

2831

P12111
CDWFQGDQPTKNLVK

COL6A3

2836

P12111
WDIKTGQCLQTLQGP

FBXW7

606

Q969H0
GQCTAVPDTEKEQEW

GPAT2

411

Q6NUI2
VEAQWELEAQGPGQC

IFITM10

21

A6NMD0
WAQNDTEPIVLEGKC

CBLN4

26

Q9NTU7
CQWIDITDVKPGNYI

LOX

361

P28300
NCIEAHNEWRGKVNP

GLIPR1L1

36

Q6UWM5
CGPQNLNLRKEWESE

KRBOX5

106

Q7Z2F6
QLWNCPLNEGSTIEK

FAM217A

86

Q8IXS0
PQGLKNWEVVAAVAA

C4orf54

81

D6RIA3
WDQVEVIPDIACGNA

DNER

191

Q8NFT8
CGQIVENWQGNPIQK

MAU2

211

Q9Y6X3
PPQWTGKTCQLDANE

JAG1

401

P78504
KEGWEGPICAQNTND

JAG1

771

P78504
LQAYKLDPQCWGVNV

SHMT1

101

P34896
EAIKQLWQDPGIQEC

GNA14

126

O95837
QGRCTWVNPLQKTEE

RSPH6A

551

Q9H0K4
NDTGLQPWTQCEYKI

USH2A

4226

O75445
LISAPGEKTCQQTWE

ATP6V1C1

6

P21283
DNFQTCKVEGAWPLI

RGMB

176

Q6NW40
LEVWGQPAKTCSQEV

UBOX5

191

O94941
KAINQTAVECTWTGP

SORL1

1851

Q92673
CDPTFWAKNVVNLGN

TRIM33

461

Q9UPN9
AINDNGPGQWSDICK

TRIM42

681

Q8IWZ5
SQFCIWTIEAPEGQK

SEZ6L

476

Q9BYH1
RQCTGVWNQKDELPI

RMND5A

306

Q9H871
CDQWDNPAPVQHVKI

SMCHD1

1286

A6NHR9
WVPCGKADTNVQGNR

TBR1

271

Q16650
RNHCVLKQNPEGQWT

RNF8

61

O76064
CPELEGQIAKLEEQW

SYNE2

4911

Q8WXH0
VEINGINPGNNDCWV

TCAF2

531

A6NFQ2
SVCEGPLKEQEWNTT

RIMOC1

266

A6NDU8
VVVSCQDITPDQWGE

FAM178B

606

Q8IXR5
VLICWESGNLNPVDS

FSD2

486

A1L4K1
CVNWDLPQEAKQALE

PIK3C3

336

Q8NEB9
QVAEQPAVKACLWGT

EPPK1

1231

P58107
CIQEVEVNCNWTLPV

PRAMEF20

206

Q5VT98
HSLKCPQAQAWQAGE

SHROOM3

601

Q8TF72
TQEWDPGKTILGIQC

TENM1

2466

Q9UKZ4
SDGCEEPKQQVSWEQ

SPINDOC

61

Q9BUA3
LQWQLINKGCPTDET

TECTB

216

Q96PL2
EAQGDKWVTPCSLIN

PKHD1

181

P08F94
QPLKSVRCNNEQWGL

SPATA31C1

1141

P0DKV0
AAQSNWEKVVPENLG

SRP72

156

O76094
VKCIRNEDGTWLTPN

SP110

486

Q9HB58
IECNKDVPGISQINW

OMA1

271

Q96E52
NPTNTIVCKAHGEWN

OSBPL10

646

Q9BXB5
AQANAIGPWIQAKVE

ACTN3

651

Q08043
GNDKVPGAWTEACEQ

ALDH1L1

226

O75891
WCDKIQGSTIPINQA

ALDH1L1

536

O75891
NTGNVCIWPSEEVLA

CAMKMT

121

Q7Z624
IEKWQEVANICSQNG

CLHC1

536

Q8NHS4
RSWKEPCQVQSCQEE

NCAPH

391

Q15003
ECWIPAKETEQINGN

C12orf29

116

Q8N999
SQEKIFCGQIWPVDQ

PROKR1

211

Q8TCW9
CSLKDIVPQNSNEGW

RNF17

576

Q9BXT8
WQGETQEFCPNAKVV

RND2

101

P52198
CPLEGKANKNVQWDE

XYLT1

301

Q86Y38
VPNQTCPNTVWKIDD

ZNF268

146

Q14587
FPEVQQDEGKWDNCL

SPATA46

116

Q5T0L3
EKGQVCLPVISAENW

UBE2L5

81

A0A1B0GUS4
CTWNIEVPNNQHVKV

ST14

366

Q9Y5Y6
TLGWIPSDNSICVQE

SUSD4

106

Q5VX71
ENGQICLPIISSENW

UBE2L6

81

O14933
ADLHPVGWCTQNNKV

SFMBT2

126

Q5VUG0
KGENINICWSPDGQT

THOC3

141

Q96J01
GPRWCAVQGQVDEKT

RAET1G

46

Q6H3X3
GPRWCAVQGQVDEKT

RAET1L

46

Q5VY80
GSDNVEWNNKIPACP

PKHD1L1

2396

Q86WI1
CNPNCETQKWTVNGD

NSD3

1226

Q9BZ95
CEPNCETQKWTVNGQ

SETD2

1631

Q9BYW2
NGNFPKACELWEQIL

TTC38

121

Q5R3I4
TAIQAWQQNKCPEVE

VPS13B

2611

Q7Z7G8
WQQNKCPEVEELVFS

VPS13B

2616

Q7Z7G8
VGNNDPSWNQEVKLE

ZGRF1

391

Q86YA3
IQAWAQKQCPQSGEE

ZKSCAN2

101

Q63HK3
WELKAVPSQQQGICK

ZNF74

116

Q16587
QGLWVLQDCQEAPLV

WDR4

301

P57081
SVVVSQPNKENWCQD

PLEKHG1

1146

Q9ULL1
GPRWCAVQGQVDEKT

ULBP2

46

Q9BZM5
VQEGRAWINPKEGCK

RARRES1

86

P49788
QTACEQPGQKWQCIE

SULF1

451

Q8IWU6
KVWLIEVNGAPACAQ

TTL

326

Q8NG68
ETQIWICKPTASNQG

TTLL10

306

Q6ZVT0
CSTVEGKWQQRLKNP

UIMC1

601

Q96RL1
EQLGQKWQCVEDATG

SULF2

456

Q8IWU5
EPDIQWVKDGAVVQN

TYRO3

71

Q06418
QKYDLPCTQGQWTIQ

TMPRSS6

391

Q8IU80
EKGQVCLPVISAENW

UBE2L3

81

P68036
DAWNKNCAILINPQG

ZAN

1736

Q9Y493
HCVVNDTKPGNVTWN

NALCN

206

Q8IZF0