Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	phospholipase D activator activity	ARF1 ARF4	6.42e-05	3	93	2	GO:1990583
GeneOntologyCellularComponent	Golgi membrane	B3GALT4 RNF121 CHST10 ATP6AP1 FKRP GOLPH3 HEPACAM2 UNC93B1 PAQR3 ARF1 ARF3 ARF4 B4GALT1	7.51e-06	721	86	13	GO:0000139
Domain	ARF	ARF1 ARF3 ARF4 ARF5	8.70e-06	29	85	4	PS51417
Domain	Small_GTPase_ARF	ARF1 ARF3 ARF4 ARF5	8.70e-06	29	85	4	IPR024156
Domain	Arf	ARF1 ARF3 ARF4 ARF5	1.14e-05	31	85	4	PF00025
Domain	Small_GTPase_ARF/SAR	ARF1 ARF3 ARF4 ARF5	1.48e-05	33	85	4	IPR006689
Domain	NUT	NUTM2B NUTM2A	2.03e-04	5	85	2	IPR024310
Domain	NUT_N	NUTM2B NUTM2A	2.03e-04	5	85	2	IPR024309
Domain	NUT	NUTM2B NUTM2A	2.03e-04	5	85	2	PF12881
Domain	PIWI	PIWIL2 PIWIL3	5.63e-04	8	85	2	PS50822
Domain	Piwi	PIWIL2 PIWIL3	5.63e-04	8	85	2	SM00950
Domain	Piwi	PIWIL2 PIWIL3	5.63e-04	8	85	2	IPR003165
Domain	Piwi	PIWIL2 PIWIL3	5.63e-04	8	85	2	PF02171
Domain	PAZ	PIWIL2 PIWIL3	7.22e-04	9	85	2	PS50821
Domain	PAZ	PIWIL2 PIWIL3	7.22e-04	9	85	2	SM00949
Domain	PAZ_dom	PIWIL2 PIWIL3	7.22e-04	9	85	2	IPR003100
Domain	PAZ	PIWIL2 PIWIL3	7.22e-04	9	85	2	PF02170
Domain	Small_GTPase	RAN ARF1 ARF3 ARF4 ARF5	8.19e-04	160	85	5	IPR001806
Domain	Small_GTP-bd_dom	RAN ARF1 ARF3 ARF4 ARF5	9.92e-04	167	85	5	IPR005225
Domain	-	RAPGEF3 KCNH2 GGCX	1.36e-03	48	85	3	2.60.120.10
Domain	RmlC-like_jellyroll	RAPGEF3 KCNH2 GGCX	1.62e-03	51	85	3	IPR014710
Domain	FA58C	MFGE8 DCBLD1	4.06e-03	21	85	2	SM00231
Domain	FA58C_3	MFGE8 DCBLD1	4.06e-03	21	85	2	PS50022
Domain	FA58C_1	MFGE8 DCBLD1	4.06e-03	21	85	2	PS01285
Domain	FA58C_2	MFGE8 DCBLD1	4.06e-03	21	85	2	PS01286
Pubmed	ADP-ribosylation factor is functionally and physically associated with the Golgi complex.	ARF1 ARF3 ARF4 ARF5	2.50e-10	5	94	4	2105501
Pubmed	Cloning of two novel ADP-ribosylation factor-like proteins and characterization of their differential expression in 3T3-L1 cells.	ARF1 ARF3 ARF4 ARF5	3.47e-09	8	94	4	8195219
Pubmed	Structure and intracellular localization of mouse ADP-ribosylation factors type 1 to type 6 (ARF1-ARF6).	ARF1 ARF3 ARF4 ARF5	3.47e-09	8	94	4	8947846
Pubmed	Interaction of GRASP, a protein encoded by a novel retinoic acid-induced gene, with members of the cytohesin family of guanine nucleotide exchange factors.	ARF1 ARF3 ARF4 ARF5	1.04e-08	10	94	4	10828067
Pubmed	Human and Giardia ADP-ribosylation factors (ARFs) complement ARF function in Saccharomyces cerevisiae.	ARF3 ARF4 ARF5	1.91e-08	3	94	3	1447192
Pubmed	ARF1 and ARF4 regulate recycling endosomal morphology and retrograde transport from endosomes to the Golgi apparatus.	ARF1 ARF3 ARF4	1.91e-08	3	94	3	23783033
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	RNF121 USP34 RAN AUP1 VPS13C MIEF1 RNF213 TRIP12 ADCY9 ARF1 ARF3 ARF4 RPL15 ARF5	2.30e-08	777	94	14	35844135
Pubmed	Two distinct populations of ARF bound to Golgi membranes.	ARF3 ARF4 ARF5	7.63e-08	4	94	3	8491770
Pubmed	Arfaptin 1, a putative cytosolic target protein of ADP-ribosylation factor, is recruited to Golgi membranes.	ARF1 ARF3 ARF5	1.90e-07	5	94	3	9038142
Pubmed	An Arf/Rab cascade controls the growth and invasiveness of glioblastoma.	ARF1 ARF4 ARF5	3.80e-07	6	94	3	33443570
Pubmed	WLS retrograde transport to the endoplasmic reticulum during Wnt secretion.	ARF3 ARF4 ARF5	3.80e-07	6	94	3	24768165
Pubmed	GGA proteins associate with Golgi membranes through interaction between their GGAH domains and ADP-ribosylation factors.	ARF1 ARF3 ARF5	6.64e-07	7	94	3	11950392
Pubmed	Identification of a new Pyk2 target protein with Arf-GAP activity.	RAN ARF1 ARF5	6.64e-07	7	94	3	10022920
Pubmed	Coated vesicle assembly in the Golgi requires only coatomer and ARF proteins from the cytosol.	ARF3 ARF4 ARF5	1.06e-06	8	94	3	8355790
Pubmed	GORAB scaffolds COPI at the trans-Golgi for efficient enzyme recycling and correct protein glycosylation.	ARF1 ARF3 ARF5	4.13e-06	12	94	3	30631079
Pubmed	Characterization of the human gene encoding ADP-ribosylation factor 1, a guanine nucleotide-binding activator of cholera toxin.	ARF1 ARF3	7.23e-06	2	94	2	1577740
Pubmed	Assignment of human ADP ribosylation factor (ARF) genes ARF1 and ARF3 to chromosomes 1q42 and 12q13, respectively.	ARF1 ARF3	7.23e-06	2	94	2	8661066
Pubmed	Molecular cloning, characterization, and expression of human ADP-ribosylation factors: two guanine nucleotide-dependent activators of cholera toxin.	ARF1 ARF3	7.23e-06	2	94	2	2474826
Pubmed	Human ADP-ribosylation factors. A functionally conserved family of GTP-binding proteins.	ARF1 ARF4	7.23e-06	2	94	2	1899243
Pubmed	Cyclic AMP-Epac signaling pathway contributes to repression of PUMA transcription in melanoma cells.	RAPGEF3 BBC3	7.23e-06	2	94	2	28489680
Pubmed	Class II ADP-ribosylation factors are required for efficient secretion of dengue viruses.	ARF4 ARF5	7.23e-06	2	94	2	22105072
Pubmed	hMSCs-derived exosome circCDK13 inhibits liver fibrosis by regulating the expression of MFGE8 through miR-17-5p/KAT2B.	MFGE8 KAT2B	7.23e-06	2	94	2	35484432
Pubmed	ARF1 and ARF3 are required for the integrity of recycling endosomes and the recycling pathway.	ARF1 ARF3	7.23e-06	2	94	2	22971977
Pubmed	DDB2 is involved in ubiquitination and degradation of PAQR3 and regulates tumorigenesis of gastric cancer cells.	DDB2 PAQR3	7.23e-06	2	94	2	26205499
Pubmed	The Vici syndrome protein EPG5 regulates intracellular nucleic acid trafficking linking autophagy to innate and adaptive immunity.	RAN EPG5	7.23e-06	2	94	2	29130391
Pubmed	Deletion of Class II ADP-Ribosylation Factors in Mice Causes Tremor by the Nav1.6 Loss in Cerebellar Purkinje Cell Axon Initial Segments.	ARF4 ARF5	2.16e-05	3	94	2	31201232
Pubmed	GBF1-Arf-COPI-ArfGAP-mediated Golgi-to-ER transport involved in regulation of lipid homeostasis.	ARF4 ARF5	2.16e-05	3	94	2	22185782
Pubmed	The clinicopathologic features of YWHAE-FAM22 endometrial stromal sarcomas: a histologically high-grade and clinically aggressive tumor.	NUTM2B NUTM2A	2.16e-05	3	94	2	22456610
Pubmed	Interaction of calcium-dependent activator protein for secretion 1 (CAPS1) with the class II ADP-ribosylation factor small GTPases is required for dense-core vesicle trafficking in the trans-Golgi network.	ARF4 ARF5	2.16e-05	3	94	2	20921225
Pubmed	ARAP1 regulates the ring size of circular dorsal ruffles through Arf1 and Arf5.	ARF1 ARF5	2.16e-05	3	94	2	22573888
Pubmed	Identification of arfophilin, a target protein for GTP-bound class II ADP-ribosylation factors.	ARF4 ARF5	2.16e-05	3	94	2	10593962
Pubmed	Class I Arfs (Arf1 and Arf3) and Arf6 are localized to the Flemming body and play important roles in cytokinesis.	ARF1 ARF3	2.16e-05	3	94	2	26330566
Pubmed	Dissecting the role of the ARF guanine nucleotide exchange factor GBF1 in Golgi biogenesis and protein trafficking.	ARF1 ARF4	2.16e-05	3	94	2	17956946
Pubmed	ADP ribosylation factors 1 and 4 and group VIA phospholipase A₂ regulate morphology and intraorganellar traffic in the endoplasmic reticulum-Golgi intermediate compartment.	ARF1 ARF4	2.16e-05	3	94	2	20881058
Pubmed	LSM12-EPAC1 defines a neuroprotective pathway that sustains the nucleocytoplasmic RAN gradient.	RAN RAPGEF3	2.16e-05	3	94	2	33362237
Pubmed	Interaction of the PDZ domain of human PICK1 with class I ADP-ribosylation factors.	ARF1 ARF3	2.16e-05	3	94	2	10623590
Pubmed	The clinical phenotype of YWHAE-NUTM2B/E positive pediatric clear cell sarcoma of the kidney.	NUTM2E NUTM2B	2.16e-05	3	94	2	26542179
Pubmed	Possible role of HIWI2 in modulating tight junction proteins in retinal pigment epithelial cells through Akt signaling pathway.	PIWIL2 PIWIL3	4.32e-05	4	94	2	28025795
Pubmed	Genetic variants in Piwi-interacting RNA pathway genes confer susceptibility to spermatogenic failure in a Chinese population.	PIWIL2 PIWIL3	4.32e-05	4	94	2	20940137
Pubmed	The arf6 GAP centaurin alpha-1 is a neuronal actin-binding protein which also functions via GAP-independent activity to regulate the actin cytoskeleton.	ARF1 ARF5	4.32e-05	4	94	2	15679100
Pubmed	Gentiopicroside targets PAQR3 to activate the PI3K/AKT signaling pathway and ameliorate disordered glucose and lipid metabolism.	DDB2 PAQR3	4.32e-05	4	94	2	35755276
Pubmed	Phosphatidylinositol 4-phosphate 5-kinase alpha is a downstream effector of the small G protein ARF6 in membrane ruffle formation.	ARF1 ARF5	4.32e-05	4	94	2	10589680
Pubmed	Drafting the CLN3 protein interactome in SH-SY5Y human neuroblastoma cells: a label-free quantitative proteomics approach.	AUP1 ARF3 ARF4 ARF5	4.72e-05	73	94	4	23464991
Pubmed	A new paxillin-binding protein, PAG3/Papalpha/KIAA0400, bearing an ADP-ribosylation factor GTPase-activating protein activity, is involved in paxillin recruitment to focal adhesions and cell migration.	ARF1 ARF5	7.19e-05	5	94	2	10749932
Pubmed	Munc18 interacting proteins: ADP-ribosylation factor-dependent coat proteins that regulate the traffic of beta-Alzheimer's precursor protein.	ARF3 ARF4	7.19e-05	5	94	2	12842896
Pubmed	Duplicated KOX zinc finger gene clusters flank the centromere of human chromosome 10: evidence for a pericentric inversion during primate evolution.	ZNF33A ZNF33B	7.19e-05	5	94	2	8464732
Pubmed	Calcium-dependent activator protein for secretion 2 interacts with the class II ARF small GTPases and regulates dense-core vesicle trafficking.	ARF4 ARF5	7.19e-05	5	94	2	22111578
Pubmed	Fukutin-related protein associates with the sarcolemmal dystrophin-glycoprotein complex.	FKRP DYSF	1.08e-04	6	94	2	17452335
Pubmed	Role of oligosaccharides in the processing and maturation of envelope glycoproteins of human immunodeficiency virus type 1.	B3GALT4 MAN2C1 B4GALT1	1.39e-04	37	94	3	2541446
Pubmed	Biosynthesis and processing of human immunodeficiency virus type 1 envelope glycoproteins: effects of monensin on glycosylation and transport.	B3GALT4 MAN2C1 B4GALT1	1.39e-04	37	94	3	2542563
Pubmed	The interaction of Epac1 and Ran promotes Rap1 activation at the nuclear envelope.	RAN RAPGEF3	1.50e-04	7	94	2	20547757
Pubmed	Evidence that mannosyl residues are involved in human immunodeficiency virus type 1 (HIV-1) pathogenesis.	B3GALT4 MAN2C1 B4GALT1	1.51e-04	38	94	3	2829950
Pubmed	Characterization of the secreted, native gp120 and gp160 of the human immunodeficiency virus type 1.	B3GALT4 MAN2C1 B4GALT1	1.51e-04	38	94	3	2187500
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	USP34 ATP6AP1 ASB6 VPS13C MIEF1 RNF213 SLC26A6 ADCY9 GGCX	1.69e-04	733	94	9	34672954
Pubmed	Site-specific cross-linking reveals a differential direct interaction of class 1, 2, and 3 ADP-ribosylation factors with adaptor protein complexes 1 and 3.	ARF1 ARF5	2.00e-04	8	94	2	11926829
Pubmed	Expression analysis of type I ARF small GTPases ARF1-3 during mouse brain development.	ARF1 ARF3	2.00e-04	8	94	2	38227057
Pubmed	Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family.	PTPN2 ATP6AP1 AUP1 CNOT10 MRPL38 GOLPH3 SIL1 ARF1 ARF4 ARF5	2.14e-04	931	94	10	27432908
Pubmed	ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.	RNF121 PTPN2 RAN ATP6AP1 AUP1 SLC26A6 ADCY9 SIL1 RPL15 ARF5	2.56e-04	952	94	10	38569033
Pubmed	Identification of eight members of the Argonaute family in the human genome.	PIWIL2 PIWIL3	2.57e-04	9	94	2	12906857
Pubmed	Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.	CHST10 ATP6AP1 AUP1 CACHD1 GGCX SIL1 ARF1 ARF4	2.62e-04	613	94	8	22268729
Pubmed	Glycosylation and processing of the human immunodeficiency virus type 1 envelope protein.	B3GALT4 MAN2C1 B4GALT1	2.67e-04	46	94	3	2649653
Pubmed	HIV-1 gp120 N-linked glycosylation differs between plasma and leukocyte compartments.	MAN2C1 B4GALT1	3.21e-04	10	94	2	18215327
Pubmed	Glycosylation site-specific analysis of HIV envelope proteins (JR-FL and CON-S) reveals major differences in glycosylation site occupancy, glycoform profiles, and antigenic epitopes' accessibility.	MAN2C1 B4GALT1	3.21e-04	10	94	2	18330979
Pubmed	Env length and N-linked glycosylation following transmission of human immunodeficiency virus Type 1 subtype B viruses.	MAN2C1 B4GALT1	3.21e-04	10	94	2	18314154
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	PTPN2 THNSL1 NET1 CNOT10 NDUFA10 TRIP12 DDB2 ARF4 KLHL22 WDR48	3.92e-04	1005	94	10	19615732
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	USP34 NET1 ZSCAN4 DYSF SLC26A6 ARF1	4.67e-04	363	94	6	14691545
Pubmed	Autonomous and nonautonomous roles of Hedgehog signaling in regulating limb muscle formation.	NET1 SIX4	4.69e-04	12	94	2	22987639
Pubmed	Evolutionarily conserved regulators of tau identify targets for new therapies.	RAN ATP6AP1 AUP1 ARF1 ARF3 ARF4 ARF5	5.12e-04	516	94	7	36610398
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	RAN AUP1 TELO2 NDUFA10 GGCX ARF1 ARF3 ARF4 RPL15 ARF5 WDR48	5.85e-04	1257	94	11	37317656
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	USP34 ACSBG1 TELO2 CASKIN2 VPS13C CACHD1 ADCY9	5.93e-04	529	94	7	14621295
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	TBC1D8 USP34 ATP6AP1 FKRP RNF213 UNC93B1 NDUFA10 SLC23A2 ADCY9 B4GALT1	5.97e-04	1061	94	10	33845483
Pubmed	Twenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering.	ZNF33A ZNF33B	6.44e-04	14	94	2	2014798
Pubmed	A genome-wide IR-induced RAD51 foci RNAi screen identifies CDC73 involved in chromatin remodeling for DNA repair.	RAN ARF1 ARF3 ARF4	8.08e-04	153	94	4	27462432
Pubmed	Identification and characterization of large galactosyltransferase gene families: galactosyltransferases for all functions.	B3GALT4 B4GALT1	8.46e-04	16	94	2	10580128
Pubmed	Targeted ubiquitination and degradation of G-protein-coupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex.	NFIB DDB2 ARF1 ARF4	8.68e-04	156	94	4	22952844
Pubmed	Large-scale concatenation cDNA sequencing.	CHST10 ACSBG1 RAPGEF3 MIEF1 UNC93B1 ARF1 RPL15	8.98e-04	568	94	7	9110174
Pubmed	Viral protein engagement of GBF1 induces host cell vulnerability through synthetic lethality.	ARF1 ARF4 ARF5	9.57e-04	71	94	3	36305789
Pubmed	Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci.	PTPN2 PHF19	9.57e-04	17	94	2	21383967
Pubmed	Neuronal Rap1 Regulates Energy Balance, Glucose Homeostasis, and Leptin Actions.	PTPN2 RAPGEF3	1.08e-03	18	94	2	27626668
Pubmed	Phosphoinositide-specific phospholipase C β 1b (PI-PLCβ1b) interactome: affinity purification-mass spectrometry analysis of PI-PLCβ1b with nuclear protein.	RAN ARF3 ARF4 RPL15	1.17e-03	169	94	4	23665500
Pubmed	A quantitative atlas of mitotic phosphorylation.	KAT2B RNF213	1.33e-03	20	94	2	18669648
Pubmed	Limb-Girdle Muscular Dystrophy Overview – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY	FKRP DYSF	1.47e-03	21	94	2	20301582
Pubmed	SIX1 and SIX4 homeoproteins regulate PAX7+ progenitor cell properties during fetal epaxial myogenesis.	EFNA4 SIX4	1.47e-03	21	94	2	32591430
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	USP34 ATP6AP1 FKRP DCBLD1 RNF213 CACHD1 UNC93B1 GGCX SIL1 B4GALT1	1.52e-03	1201	94	10	35696571
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	USP34 ATP6AP1 AUP1 NFIB FAM169A B4GALT1	1.53e-03	457	94	6	32344865
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	RAN DISP1 ARF1 ARF3 ARF4 RPL15 EPG5 ARF5	1.56e-03	807	94	8	30575818
Pubmed	Usp12 stabilizes the T-cell receptor complex at the cell surface during signaling.	USP34 WDR48	1.61e-03	22	94	2	26811477
Pubmed	F-Box Protein FBXO22 Mediates Polyubiquitination and Degradation of CD147 to Reverse Cisplatin Resistance of Tumor Cells.	ARF3 ARF4	1.61e-03	22	94	2	28117675
Pubmed	Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability.	AUP1 DCBLD1 CACHD1 SLC23A2 ARF1 ARF4	1.71e-03	467	94	6	30194290
Pubmed	FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.	PTPN2 ATP6AP1 AUP1 ADCY9 GGCX KLHL22	1.73e-03	468	94	6	31056421
Pubmed	ADP Ribosylation Factor 4 (Arf4) Regulates Radial Migration through N-Cadherin Trafficking during Cerebral Cortical Development.	ARF4 ARF5	1.76e-03	23	94	2	37848288
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	RNF121 USP34 RAN RNF213 UNC93B1 NDUFA10 GGCX ARF3 ARF4 RPL15 ARF5	1.86e-03	1451	94	11	30550785
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	KAT2B CNOT10 FAM169A CEP76 TRIP12 ARF4 ARF5	1.86e-03	645	94	7	25281560
Pubmed	Interactome mapping defines BRG1, a component of the SWI/SNF chromatin remodeling complex, as a new partner of the transcriptional regulator CTCF.	RAN ARF4 RPL15	1.89e-03	90	94	3	30459231
Pubmed	Interactome analysis of Bag-1 isoforms reveals novel interaction partners in endoplasmic reticulum-associated degradation.	RAN ARF1 ARF4 RPL15 ARF5	1.98e-03	327	94	5	34428256
Pubmed	SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.	RAN ATP6AP1 AUP1 TELO2 GGCX ARF4 RPL15	2.06e-03	657	94	7	36180527
Pubmed	Protein interaction screening for the ankyrin repeats and suppressor of cytokine signaling (SOCS) box (ASB) family identify Asb11 as a novel endoplasmic reticulum resident ubiquitin ligase.	RAN ASB6 ARF4 RPL15	2.08e-03	198	94	4	24337577
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PTPN2 ATP6AP1 TELO2 CASKIN2 RNF213 CACHD1 SIX4 ADCY9 WDR48	2.15e-03	1049	94	9	27880917
Pubmed	Transcriptional Repression of Aerobic Glycolysis by OVOL2 in Breast Cancer.	ARF1 ARF3 ARF4	2.21e-03	95	94	3	35896951
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	PTPN2 THNSL1 ATP6AP1 AUP1 TELO2 VPS13C FAM169A MIEF1 RNF213 MRPL38 ADCY9	2.36e-03	1496	94	11	32877691
Interaction	CLN3 interactions	B3GALT4 AUP1 TELO2 ARF3 ARF4 ARF5	9.18e-06	115	85	6	int:CLN3
Cytoband	Ensembl 112 genes in cytogenetic band chr7q11	SPDYE11 SPDYE17 SPDYE10 SPDYE13 SPDYE15 SPDYE8 SPDYE9 SPDYE12 SPDYE14	6.31e-09	271	96	9	chr7q11
Cytoband	7q11.23	SPDYE10 SPDYE8 SPDYE9 SPDYE14	5.36e-05	97	96	4	7q11.23
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	ARF1 ARF3 ARF4 ARF5	2.81e-06	31	58	4	357
GeneFamily	Argonaute/PIWI family	PIWIL2 PIWIL3	2.80e-04	8	58	2	408
GeneFamily	Speedy/RINGO cell cycle regulator family	SPDYE8 SPDYE9	6.54e-04	12	58	2	756
Computational	Small monomeric GTPases.	RAN ARF1 ARF4 ARF5	2.45e-05	43	43	4	MODULE_86
Computational	Genes in the cancer module 87.	RAN ARF1 ARF4 ARF5	2.68e-05	44	43	4	MODULE_87
Disease	Endometrial Stromal Sarcoma	NUTM2B NUTM2A	7.59e-05	5	82	2	C0206630
Disease	Clear cell sarcoma of kidney	NUTM2E NUTM2B	1.14e-04	6	82	2	C0334488
Disease	Malignant neoplasm of breast	MFGE8 MAN2C1 NET1 ACCS HEPACAM2 SIX4 DYSF PKDREJ ARF1 PRODH EPG5	1.86e-04	1074	82	11	C0006142
Disease	Autosomal recessive limb-girdle muscular dystrophy	FKRP DYSF	6.79e-04	14	82	2	cv:C2931907
Disease	muscular dystrophy (is_implicated_in)	FKRP DYSF	1.01e-03	17	82	2	DOID:9884 (is_implicated_in)
Disease	muscular dystrophy (implicated_via_orthology)	FKRP DYSF	1.55e-03	21	82	2	DOID:9884 (implicated_via_orthology)
Disease	colorectal cancer, hormone replacement therapy	DCBLD1 NDUFA10 DISP1	1.91e-03	88	82	3	EFO_0003961, MONDO_0005575
Disease	Limb-girdle muscular dystrophy	FKRP DYSF	2.37e-03	26	82	2	cv:C0686353
Disease	immune system disease	PTPN2 PHF19	2.75e-03	28	82	2	EFO_0000540

Protein segments in the cluster

Peptide	Gene	Start	Entry
QRHRPSPWRVLYNLI	BBC3	161	Q9BXH1
QALISQHLWYREQPI	EPG5	1151	Q9HCE0
IIPFRNRQEHLKYWL	B4GALT1	181	P15291
AQSPLRYLHVLWQQD	ANKRD54	61	Q6NXT1
DWINQVYLPENHARL	ACCS	371	Q96QU6
QDKIRPLWRHYFQNT	ARF5	71	P84085
EVPLLYLGRVHWRVN	B3GALT4	221	O96024
RRQWYLHAVANPGLI	CACHD1	756	Q5VU97
QDKIRPLWRHYFQNT	ARF3	71	P61204
KHLCRVAIRLYLQPW	ASB6	376	Q9NWX5
WREYLQIRPSHNSRL	CEP76	291	Q8TAP6
GTRPIVQQQRIWHLY	DNHD1	1011	Q96M86
WLPAVVVLHERYLLN	DISP1	651	Q96F81
VTYKNVPNWHRDLVR	RAN	96	P62826
LPHVRAIAYTWFNLQ	NFIB	21	O00712
RRWQPLYLEIRNESH	PTPN2	16	P17706
HPNYLTQQWQRLRSI	PAQR3	191	Q6TCH7
HILVSWLPRLNAYRG	NET1	251	Q7Z628
LVLHPSAYIRNGWNL	CACNA1F	151	O60840
YVRILPVAWHNRIAL	MFGE8	366	Q08431
NYWHLEAPSQRRLRS	KAT2B	256	Q92831
RYLHWVRQAPGQALE	IGHV1-45	51	A0A0A0MS14
NPLRQRLEEYFQHAW	KCNH2	691	Q12809
LPSYHNLEWRLDVQL	COMMD2	121	Q86X83
LRHVVYWNSSNPRLL	EFNA4	26	P52798
KPHRLAQYDNLWRLS	MIEF1	326	Q9NQG6
KAAWHPRYNLIVVGR	DDB2	341	Q92466
LVLPVNIAEHLLQYW	NPBWR2	96	P48146
LHYAAWQGRLEPVRL	CASKIN2	86	Q8WXE0
GPWLKQDNRTLYHLR	NDUFA10	281	O95299
RYDPRHNRWFQIQSL	KLHL22	371	Q53GT1
WNPLKLHYQLRNVRE	GOLPH3	161	Q9H4A6
NAAARPYHIQKWAIL	ACSBG1	671	Q96GR2
DQADWLLRNIIPYHV	ADCY9	1026	O60503
QDKIRPLWRHYFQNT	ARF1	71	P84077
GHWYQRIPVTRALQR	FAM169A	246	Q9Y6X4
RLVFQHSRAWPLLQT	MBOAT4	316	Q96T53
QFLYPAAQLQHLWRL	MAN2C1	556	Q9NTJ4
TRLAYQWLKNGRPVH	HEPACAM2	176	A8MVW5
LFYVSWLQHQPRNSR	FKRP	21	Q9H9S5
YVRVVPQTWHQRIAL	DCBLD1	391	Q8N8Z6
QLLANHFRVISRPQW	PIWIL3	126	Q7Z3Z3
QWRDQLRPSQLLHLF	DYSF	1691	O75923
ENFRLWQHYKPLARR	NUTM2A	331	Q8IVF1
ENFRLWQHYKPLARR	NUTM2B	331	A6NNL0
ENFRLWQHYKPLARR	NUTM2E	331	B1AL46
VRLLWHLRNYTKTPN	TAS2R42	296	Q7RTR8
LLAVPAAVYRHLWRD	LTB4R2	151	Q9NPC1
LVYHPQLRAQVWRYL	RHBDL3	201	P58872
VLQQHRLQIWPGYAA	PIWIL2	351	Q8TC59
RAYALLLQHLPVLVW	SLC26A6	66	Q9BXS9
YRWLNSVLLPLLHND	PKDREJ	1761	Q9NTG1
ADLYFHLWPQVQRQL	FAM20A	21	Q96MK3
AWPALLARHEQLLYV	PRODH	81	O43272
LPSWQYQRIHFFLAL	SPDYE10	151	P0DUX0
LPSWQYQRIHFFLAL	SPDYE11	151	P0DTA3
LRQYQRPPHSLWASL	SPPL2C	306	Q8IUH8
LPSWQYQRIHFFLAL	SPDYE8	151	P0DUD1
SANHPLLQQLWYKAR	SIX4	176	Q9UIU6
LQQYRQVHLLPGLWE	SIL1	361	Q9H173
IPDVHLYRLCWVLRN	SLC5A4	551	Q9NY91
YLHQRVCWRLVEQVP	TELO2	246	Q9Y4R8
QDRIRPLWKHYFQNT	ARF4	71	P18085
TRISHYRPWINQILQ	CMA1	231	P23946
VRYLGDPNHRWLDLQ	CHST10	241	O43529
AVQVYHANPRLWLRL	CNOT10	381	Q9H9A5
YQVRWLRPVHRQLGE	AUP1	221	Q9Y679
LPWVHLAYQRFRSRL	RNF213	3811	Q63HN8
ALERLLDPSWNHRVY	RAPGEF3	786	O95398
LDPSWNHRVYRLALA	RAPGEF3	791	O95398
RNAHVPLWNYAVLRG	GGCX	191	P38435
PRVLQHSWILYVAAA	UNC93B1	426	Q9H1C4
WQHLDPSQRALYRDV	ZNF33B	26	Q06732
LLQALLEYWPRTHVN	WDR48	466	Q8TAF3
EYLHWLLTNIPGNRV	MRPL38	231	Q96DV4
HIWYPRIREIQGAII	SLC23A2	206	Q9UGH3
RCWQYRQLSALHRAP	RPL15	26	P61313
LPSWQYQRIHFFLAL	SPDYE12	151	P0DUX1
LPSWQYQRIHFFLAL	SPDYE13	151	A0A494C0Z2
LPSWQYQRIHFFLAL	SPDYE14	151	P0DUD3
LPSWQYQRIHFFLAL	SPDYE15	151	P0DUD4
LPSWQYQRIHFFLAL	SPDYE17	151	P0DUD2
RVPRQGWLYLSINHL	TBC1D8	171	O95759
LPLRWVDVVHLALYN	PHF19	256	Q5T6S3
INWGRLLPQVVYHAS	THNSL1	471	Q8IYQ7
LVNRNLAASWYHKVP	VPS13C	1326	Q709C8
QLLLVQWKQRHPRSY	RNF121	66	Q9H920
ILANRLYPVSARHWF	ATP6AP1	326	Q15904
LWYVKQQLQRHADPR	PLEKHH1	936	Q9ULM0
ELQRLYRIFHSWLQP	ZSCAN4	61	Q8NAM6
WQHLDPSQRALYRDV	ZNF33A	26	Q06730
LPSWQYQRIHFFLAL	SPDYE9	151	A0A494C191
PAALWLQERQAQLRH	PLEKHG2	211	Q9H7P9
NWVERFLLAHNYPRV	USP34	2666	Q70CQ2
LWHPYNRIDSRIIEQ	TRIP12	771	Q14669
HLAYRNRNWEKELLP	TTLL13	561	A6NNM8
PNEHLRVTLWGQRLY	ZAN	2421	Q9Y493