Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	semaphorin receptor activity	PLXNA4 PLXNA1 PLXNA2	5.06e-05	12	125	3	GO:0017154
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	SLK NAGK BMP2K INSRR LRRK2 OBSCN YRDC RET ACVR2B TEK TYK2 TGFBR3 FKTN ETNK2 TJP2 POLK MAP2K5	7.69e-05	938	125	17	GO:0016772
GeneOntologyMolecularFunction	transmembrane receptor protein kinase activity	INSRR RET ACVR2B TEK TGFBR3	1.95e-04	85	125	5	GO:0019199
GeneOntologyMolecularFunction	kinase activity	SLK NAGK BMP2K INSRR LRRK2 OBSCN RET ACVR2B TEK TYK2 TGFBR3 ETNK2 TJP2 MAP2K5	3.08e-04	764	125	14	GO:0016301
GeneOntologyBiologicalProcess	regulation of hydrolase activity	DPEP1 COL7A1 RRP1B ARHGEF5 LRRK2 INTS1 RET GSN PLXNA4 LRP1 AGAP7P MMP9 MAP2K5 CX3CL1 AGAP4 AGAP6 PLXNA1 PLXNA2 RCN3	8.47e-07	878	121	19	GO:0051336
GeneOntologyBiologicalProcess	regulation of anatomical structure size	SEMA4F TRPM4 DISC1 LRRK2 SLC26A5 PLEKHG2 RET GSN TGFBR3 VILL PLXNA4 KCNMA1 LRP1 MACF1 CX3CL1	3.42e-06	618	121	15	GO:0090066
GeneOntologyBiologicalProcess	regulation of axonogenesis	SEMA4F DISC1 RET PLXNA4 LRP1 MACF1 PLXNA1 PLXNA2	1.79e-05	192	121	8	GO:0050770
GeneOntologyBiologicalProcess	regulation of GTPase activity	RRP1B ARHGEF5 LRRK2 PLXNA4 AGAP7P CX3CL1 AGAP4 AGAP6 PLXNA1 PLXNA2	2.87e-05	335	121	10	GO:0043087
GeneOntologyBiologicalProcess	embryo development	KIFBP ADAMTS3 INTS1 APLP2 RET ACVR2B GTF2IRD1 RUVBL2 NCAPG2 TGFBR3 NCOR2 POGLUT1 ETNK2 PLXNA4 DCHS1 LRP5 MACF1 LRRC7 MAP2K5 NOP2 BAG6 PLXNA2	2.92e-05	1437	121	22	GO:0009790
GeneOntologyBiologicalProcess	regulation of cellular component size	SEMA4F DISC1 SLC26A5 PLEKHG2 RET GSN VILL PLXNA4 KCNMA1 LRP1 MACF1	4.27e-05	426	121	11	GO:0032535
GeneOntologyBiologicalProcess	regulation of cell size	SEMA4F DISC1 SLC26A5 RET PLXNA4 KCNMA1 LRP1 MACF1	5.53e-05	225	121	8	GO:0008361
GeneOntologyBiologicalProcess	positive regulation of axonogenesis	DISC1 PLXNA4 LRP1 MACF1 PLXNA1 PLXNA2	5.73e-05	114	121	6	GO:0050772
GeneOntologyBiologicalProcess	regulation of protein binding	DISC1 LRRK2 APLP2 PPP2CA PPP2CB FKTN LRP1 MMP9	6.07e-05	228	121	8	GO:0043393
GeneOntologyBiologicalProcess	positive regulation of binding	LRRK2 EBF2 PPP2CA PPP2CB LRP1 EIF3C MMP9	6.55e-05	170	121	7	GO:0051099
GeneOntologyBiologicalProcess	positive regulation of molecular function	ARHGEF5 INSRR LRRK2 RET TEK SIRT3 GSN EBF2 TGFBR3 PPP2CA PPP2CB LRP1 LRP5 EIF3C AGAP7P MMP9 MAP2K5 CX3CL1 AGAP4 AGAP6 RCN3	8.27e-05	1430	121	21	GO:0044093
GeneOntologyBiologicalProcess	positive regulation of protein metabolic process	ZC3H12A ARHGEF5 DISC1 LRRK2 SH2D3A RET TEK GSN TFR2 PPP2CA NCOR2 CD6 LRP1 EIF3C CTNND1 MMP9 MAP2K5 CX3CL1 BAG6 FGF19 RCN3	1.09e-04	1458	121	21	GO:0051247
GeneOntologyBiologicalProcess	regulation of binding	DISC1 LRRK2 APLP2 EBF2 PPP2CA PPP2CB FKTN LRP1 EIF3C MMP9	1.16e-04	396	121	10	GO:0051098
GeneOntologyBiologicalProcess	positive regulation of cellular component organization	ARHGEF5 DISC1 LRRK2 RET TEK RUVBL2 NCAPG2 GSN TFR2 PPP2CA PLXNA4 LRP1 LRP5 MACF1 LRRC7 MMP9 CX3CL1 PLXNA1 PLXNA2 RAB11FIP3	1.30e-04	1366	121	20	GO:0051130
GeneOntologyBiologicalProcess	positive regulation of protein binding	LRRK2 PPP2CA PPP2CB LRP1 MMP9	1.44e-04	85	121	5	GO:0032092
GeneOntologyBiologicalProcess	regulation of cell-matrix adhesion	SLK DISC1 TEK LRP1 MACF1 CX3CL1	1.85e-04	141	121	6	GO:0001952
GeneOntologyBiologicalProcess	negative regulation of intracellular signal transduction	FOXM1 STRN3 ZC3H12A LRRK2 OBSCN SIRT3 TGFBR3 PPP2CA PPP2CB NCOR2 FKTN LRP1 SIGLEC11 MMP9	2.37e-04	795	121	14	GO:1902532
GeneOntologyBiologicalProcess	semaphorin-plexin signaling pathway	SEMA4F PLXNA4 PLXNA1 PLXNA2	2.45e-04	52	121	4	GO:0071526
GeneOntologyBiologicalProcess	regulation of MAPK cascade	FOXM1 ZC3H12A ARHGEF5 LRRK2 RET TEK SIRT3 GSN TGFBR3 FKTN LRP1 MAP2K5 CX3CL1 FGF19	3.05e-04	815	121	14	GO:0043408
GeneOntologyBiologicalProcess	positive regulation of microtubule binding	PPP2CA PPP2CB	3.37e-04	5	121	2	GO:1904528
GeneOntologyBiologicalProcess	kidney development	LRRK2 RET ACVR2B TEK DCHS1 CTNND1 MMP9 GDF11 BAG6	3.51e-04	372	121	9	GO:0001822
GeneOntologyBiologicalProcess	MAPK cascade	FOXM1 ZC3H12A ARHGEF5 LRRK2 SH2D3A RET TEK SIRT3 GSN TGFBR3 FKTN LRP1 MAP2K5 CX3CL1 FGF19	3.60e-04	930	121	15	GO:0000165
GeneOntologyBiologicalProcess	regulation of axon extension	SEMA4F DISC1 PLXNA4 LRP1 MACF1	3.70e-04	104	121	5	GO:0030516
GeneOntologyBiologicalProcess	negative regulation of hydrolase activity	DPEP1 COL7A1 RRP1B LRRK2 INTS1 LRP1 MMP9 MAP2K5	3.79e-04	298	121	8	GO:0051346
GeneOntologyCellularComponent	receptor complex	INSRR ITGA10 RET ACVR2B TEK TFR2 TYK2 TGFBR3 CD6 PLXNA4 LRP1 LRP5 PLXNA1 PLXNA2	1.01e-05	581	125	14	GO:0043235
GeneOntologyCellularComponent	semaphorin receptor complex	PLXNA4 PLXNA1 PLXNA2	5.71e-05	13	125	3	GO:0002116
GeneOntologyCellularComponent	FAR/SIN/STRIPAK complex	STRN3 PPP2CA PPP2CB	1.34e-04	17	125	3	GO:0090443
HumanPheno	Megalocornea	KIFBP GTF2IRD1 TEK PPP2CA FKTN KCNMA1	6.33e-06	54	45	6	HP:0000485
HumanPheno	Anterior chamber mesodermal anomalies	KIFBP GTF2IRD1 TEK PPP2CA FKTN KCNMA1	6.33e-06	54	45	6	HP:0008040
Domain	Plexin_cytopl	PLXNA4 PLXNA1 PLXNA2	2.39e-05	9	125	3	PF08337
Domain	Plexin_cytoplasmic_RasGAP_dom	PLXNA4 PLXNA1 PLXNA2	2.39e-05	9	125	3	IPR013548
Domain	Plexin	PLXNA4 PLXNA1 PLXNA2	2.39e-05	9	125	3	IPR031148
Domain	IPT	EBF2 PLXNA4 PLXNA1 PLXNA2	2.98e-05	27	125	4	SM00429
Domain	Semap_dom	SEMA4F PLXNA4 PLXNA1 PLXNA2	5.23e-05	31	125	4	IPR001627
Domain	SEMA	SEMA4F PLXNA4 PLXNA1 PLXNA2	5.23e-05	31	125	4	PS51004
Domain	TIG	EBF2 PLXNA4 PLXNA1 PLXNA2	5.23e-05	31	125	4	PF01833
Domain	Sema	SEMA4F PLXNA4 PLXNA1 PLXNA2	5.23e-05	31	125	4	SM00630
Domain	Sema	SEMA4F PLXNA4 PLXNA1 PLXNA2	5.23e-05	31	125	4	PF01403
Domain	IPT	EBF2 PLXNA4 PLXNA1 PLXNA2	5.95e-05	32	125	4	IPR002909
Domain	Plexin_repeat	SEMA4F PLXNA4 PLXNA1 PLXNA2	5.95e-05	32	125	4	IPR002165
Domain	PSI	SEMA4F PLXNA4 PLXNA1 PLXNA2	5.95e-05	32	125	4	PF01437
Domain	Kinase-like_dom	SLK BMP2K INSRR LRRK2 OBSCN WDR81 RET ACVR2B TEK TYK2 ETNK2 MACF1 MAP2K5	7.07e-05	542	125	13	IPR011009
Domain	PSI	SEMA4F PLXNA4 PLXNA1 PLXNA2	2.11e-04	44	125	4	IPR016201
Domain	PSI	SEMA4F PLXNA4 PLXNA1 PLXNA2	2.51e-04	46	125	4	SM00423
Domain	Fumarylacetoacetase_C-rel	FAHD2B FAHD2A	2.64e-04	4	125	2	IPR011234
Domain	FAA_hydrolase	FAHD2B FAHD2A	2.64e-04	4	125	2	PF01557
Domain	-	FAHD2B FAHD2A	2.64e-04	4	125	2	3.90.850.10
Domain	PROTEIN_KINASE_TYR	INSRR OBSCN RET TEK TYK2	4.88e-04	97	125	5	PS00109
Domain	Tyr_kinase_AS	INSRR OBSCN RET TEK TYK2	4.88e-04	97	125	5	IPR008266
Domain	ArfGap	AGAP7P AGAP4 AGAP6	9.42e-04	29	125	3	SM00105
Domain	ARFGAP	AGAP7P AGAP4 AGAP6	9.42e-04	29	125	3	PS50115
Domain	ArfGap	AGAP7P AGAP4 AGAP6	9.42e-04	29	125	3	PF01412
Domain	ArfGAP	AGAP7P AGAP4 AGAP6	9.42e-04	29	125	3	IPR001164
Domain	PROTEIN_KINASE_ATP	SLK BMP2K INSRR LRRK2 OBSCN RET ACVR2B TEK TYK2 MAP2K5	1.04e-03	459	125	10	PS00107
Domain	Villin/Gelsolin	GSN VILL	1.21e-03	8	125	2	IPR007122
Domain	GEL	GSN VILL	1.21e-03	8	125	2	SM00262
Domain	Prot_kinase_dom	SLK BMP2K INSRR LRRK2 OBSCN RET ACVR2B TEK TYK2 MAP2K5	1.67e-03	489	125	10	IPR000719
Domain	PROTEIN_KINASE_DOM	SLK BMP2K INSRR LRRK2 OBSCN RET ACVR2B TEK TYK2 MAP2K5	1.77e-03	493	125	10	PS50011
Domain	Ankyrin_rpt	SHANK1 TRPM4 LRRK2 POTEJ AGAP7P AGAP4 AGAP6	1.93e-03	262	125	7	IPR002110
Domain	Tyr_kinase_cat_dom	INSRR RET TEK TYK2	2.89e-03	88	125	4	IPR020635
Domain	TyrKc	INSRR RET TEK TYK2	2.89e-03	88	125	4	SM00219
Domain	PP2Ac	PPP2CA PPP2CB	3.30e-03	13	125	2	SM00156
Domain	Ser/Thr-sp_prot-phosphatase	PPP2CA PPP2CB	3.30e-03	13	125	2	IPR006186
Domain	SER_THR_PHOSPHATASE	PPP2CA PPP2CB	3.30e-03	13	125	2	PS00125
Domain	SH3	SHANK1 NEBL ARHGEF5 OBSCN TJP2 MACF1	3.35e-03	216	125	6	PS50002
Domain	SH3_domain	SHANK1 NEBL ARHGEF5 OBSCN TJP2 MACF1	3.66e-03	220	125	6	IPR001452
Domain	Gelsolin	GSN VILL	3.84e-03	14	125	2	PF00626
Domain	Gelsolin-like_dom	GSN VILL	3.84e-03	14	125	2	IPR007123
Domain	ATPase_dyneun-rel_AAA	MDN1 DNAH6	3.84e-03	14	125	2	IPR011704
Domain	Ldl_recept_b	LRP1 LRP5	3.84e-03	14	125	2	PF00058
Domain	LDLRB	LRP1 LRP5	3.84e-03	14	125	2	PS51120
Domain	AAA_5	MDN1 DNAH6	3.84e-03	14	125	2	PF07728
Domain	Protein_kinase_ATP_BS	SLK INSRR LRRK2 OBSCN RET TEK TYK2 MAP2K5	4.01e-03	379	125	8	IPR017441
Domain	LY	LRP1 LRP5	4.41e-03	15	125	2	SM00135
Domain	LDLR_classB_rpt	LRP1 LRP5	4.41e-03	15	125	2	IPR000033
Domain	Ig_E-set	EBF2 PLXNA4 PLXNA1 PLXNA2	5.25e-03	104	125	4	IPR014756
Domain	-	COL7A1 APLP2	6.34e-03	18	125	2	4.10.410.10
Domain	Prtase_inh_Kunz-CS	COL7A1 APLP2	6.34e-03	18	125	2	IPR020901
Pathway	REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION	PLXNA4 PLXNA1 PLXNA2	2.42e-05	9	95	3	MM15030
Pathway	WP_NRP1TRIGGERED_SIGNALING_IN_PANCREATIC_CANCER	TGFBR3 PLXNA4 MMP9 PLXNA1 PLXNA2	3.04e-05	54	95	5	M42568
Pathway	REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION	PLXNA4 PLXNA1 PLXNA2	1.02e-04	14	95	3	MM15029
Pathway	REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION	PLXNA4 PLXNA1 PLXNA2	1.02e-04	14	95	3	M7578
Pathway	REACTOME_CRMPS_IN_SEMA3A_SIGNALING	PLXNA4 PLXNA1 PLXNA2	1.27e-04	15	95	3	MM15031
Pathway	REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION	PLXNA4 PLXNA1 PLXNA2	1.56e-04	16	95	3	M16498
Pathway	KEGG_MEDICUS_REFERENCE_COHESIN_DISSOCIATION_IN_PROPHASE	SGO1 PPP2CA PPP2CB	1.56e-04	16	95	3	M47870
Pathway	REACTOME_CRMPS_IN_SEMA3A_SIGNALING	PLXNA4 PLXNA1 PLXNA2	1.56e-04	16	95	3	M8245
Pathway	REACTOME_OTHER_SEMAPHORIN_INTERACTIONS	PLXNA4 PLXNA1 PLXNA2	2.66e-04	19	95	3	M10959
Pathway	KEGG_MEDICUS_REFERENCE_CONDENSIN_LOADING	NCAPG2 PPP2CA PPP2CB	3.11e-04	20	95	3	M47876
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SHANK1 STRN3 KIFBP SLK WDR81 SLC1A2 GSN PPP2CB NCOR2 MDN1 SEC23IP KCNMA1 DCHS1 LRP1 MACF1 LRRC7 HERC2 CTNND1 NOP2	2.38e-09	963	127	19	28671696
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	FAHD2B BMP2K FAHD2A PPP2CB TJP2 MACF1 PNPLA8 LRRC7 HERC2 CTNND1 AGAP7P AGAP4 AGAP6	7.00e-09	430	127	13	32581705
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SEMA4F TRPM4 AOC2 INTS1 OBSCN TOR4A GTF2IRD1 TYK2 PPP2CB NCOR2 THADA TNRC18 MDN1 COQ4 CPSF1 LRP5 HERC2 PLXNA1 RAB11FIP3	2.17e-08	1105	127	19	35748872
Pubmed	A semaphorin code defines subpopulations of spinal motor neurons during mouse development.	SEMA4F RET PLXNA4 PLXNA1 PLXNA2	2.41e-08	24	127	5	15869472
Pubmed	Structural Basis for Plexin Activation and Regulation.	PLXNA4 PLXNA1 PLXNA2	4.76e-08	3	127	3	27397516
Pubmed	Repulsive and attractive semaphorins cooperate to direct the navigation of cardiac neural crest cells.	PLXNA4 PLXNA1 PLXNA2	4.76e-08	3	127	3	18625214
Pubmed	Functional loss of semaphorin 3C and/or semaphorin 3D and their epistatic interaction with ret are critical to Hirschsprung disease liability.	RET PLXNA4 PLXNA1 PLXNA2	8.20e-08	12	127	4	25839327
Pubmed	Chromosome assignment of four plexin A genes (Plxna1, Plxna2, Plxna3, Plxna4) in mouse, rat, Syrian hamster and Chinese hamster.	PLXNA4 PLXNA1 PLXNA2	1.90e-07	4	127	3	11306810
Pubmed	PlexinA polymorphisms mediate the developmental trajectory of human corpus callosum microstructure.	PLXNA4 PLXNA1 PLXNA2	1.90e-07	4	127	3	25518740
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	KIFBP SLK RRP1B CARS1 APLP2 PRPF8 RUVBL2 PPP2CA THADA MDN1 MOGS SEC23IP CPSF1 PNPLA8 EIF3C CTNND1 MMP9 NOP2 BAG6 PLXNA1	2.41e-07	1425	127	20	30948266
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	RRP1B USP11 DISC1 TOMM5 NUBP2 PPP2CA PPP2CB MDN1 MOGS SEC23IP CPSF1 HERC2 CTNND1	3.73e-07	606	127	13	36538041
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	SHANK1 SLK SLC1A2 GSN PPP2CB LRP1 MACF1 LRRC7 CTNND1	3.89e-07	251	127	9	27507650
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	SLK RRP1B CARS1 PRPF8 RUVBL2 NACAD PPP2CA PPP2CB MDN1 LRP5 MACF1 LRRC7 EIF3C DNAH6 BAG6	5.17e-07	847	127	15	35235311
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	NAGK RRP1B USP11 APLP2 PRPF8 NCKAP5L NCAPG2 GSN TYK2 PPP2CA UBXN7 LRP1 TJP2 EIF3C NOP2 BAG6	5.68e-07	974	127	16	28675297
Pubmed	STRIPAK components determine mode of cancer cell migration and metastasis.	STRN3 PPP2CA PPP2CB	9.43e-07	6	127	3	25531779
Pubmed	Global loss of leucine carboxyl methyltransferase-1 causes severe defects in fetal liver hematopoiesis.	FOXM1 PPP2CA PPP2CB	9.43e-07	6	127	3	29735529
Pubmed	A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I-III.	KIFBP THNSL1 USP11 SHMT1 RETSAT SIRT3 NUBP2 MDN1 LRP1 CPSF1 CTNND1 LRRC71 CYB5R1	1.48e-06	686	127	13	28380382
Pubmed	Semaphorin-6A controls guidance of corticospinal tract axons at multiple choice points.	PLXNA4 PLXNA1 PLXNA2	1.65e-06	7	127	3	19063725
Pubmed	Increased proximal bifurcation of CA1 pyramidal apical dendrites in sema3A mutant mice.	PLXNA4 PLXNA1 PLXNA2	1.65e-06	7	127	3	19655386
Pubmed	K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.	USP11 APLP2 TOR4A GTF2IRD1 NCAPG2 PPP2CA PPP2CB NCOR2 UBXN7 CPSF1 HERC2 MAP2K5	2.37e-06	604	127	12	38803224
Pubmed	The expression of plexins during mouse embryogenesis.	PLXNA4 PLXNA1 PLXNA2	2.63e-06	8	127	3	15661641
Pubmed	Integration of opposing semaphorin guidance cues in cortical axons.	PLXNA4 PLXNA1 PLXNA2	2.63e-06	8	127	3	22368082
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	KIFBP FAHD2B NEBL ADAMTS3 USP11 FAHD2A SGO1 NACAD SIRT3 MDN1 COQ4 SUPT7L AGAP7P AGAP4 AGAP6 PLXNA2 LRRC71	2.95e-06	1242	127	17	30973865
Pubmed	GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins.	AGAP7P AGAP4 AGAP6	3.93e-06	9	127	3	12640130
Pubmed	The role of neuropilins in cell signalling.	PLXNA4 PLXNA1 PLXNA2	3.93e-06	9	127	3	19909241
Pubmed	LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.	STRN3 RRP1B USP11 PRPF8 RUVBL2 PPP2CA PPP2CB NCOR2 MOGS HERC2 CTNND1 NOP2	4.21e-06	639	127	12	23443559
Pubmed	Nuclear import of histone deacetylase 5 by requisite nuclear localization signal phosphorylation.	APLP2 PRPF8 RUVBL2 PPP2CA PPP2CB NCOR2 EIF3C NOP2	5.15e-06	258	127	8	21081666
Pubmed	Regulation of metanephric kidney development by growth/differentiation factor 11.	RET ACVR2B GDF11	5.60e-06	10	127	3	12729564
Pubmed	Plexin A3 and plexin A4 convey semaphorin signals during facial nerve development.	PLXNA4 PLXNA1 PLXNA2	5.60e-06	10	127	3	18804103
Pubmed	AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.	AGAP7P AGAP4 AGAP6	5.60e-06	10	127	3	20664521
Pubmed	A Genome-Wide Knockout Screen in Human Macrophages Identified Host Factors Modulating Salmonella Infection.	STRN3 NAGK PRPF8 PPP2CA KLHL13 HERC2 NOP2	6.46e-06	189	127	7	31594818
Pubmed	AGAP1, a novel binding partner of nitric oxide-sensitive guanylyl cyclase.	AGAP7P AGAP4 AGAP6	7.68e-06	11	127	3	15381706
Pubmed	On and off retinal circuit assembly by divergent molecular mechanisms.	PLXNA4 PLXNA1 PLXNA2	1.02e-05	12	127	3	24179230
Pubmed	Deletion of Sema3a or plexinA1/plexinA3 causes defects in sensory afferent projections of statoacoustic ganglion neurons.	PLXNA4 PLXNA1 PLXNA2	1.02e-05	12	127	3	23991118
Pubmed	PLXNA1 and PLXNA3 cooperate to pattern the nasal axons that guide gonadotropin-releasing hormone neurons.	PLXNA4 PLXNA1 PLXNA2	1.02e-05	12	127	3	31690636
Pubmed	Transcriptome profiling reveals expression signatures of cranial neural crest cells arising from different axial levels.	PLXNA4 PLXNA1 PLXNA2	1.02e-05	12	127	3	28407732
Pubmed	Transmembrane semaphorin signalling controls laminar stratification in the mammalian retina.	PLXNA4 PLXNA1 PLXNA2	1.02e-05	12	127	3	21270798
Pubmed	The deubiquitinase USP11 ameliorates intervertebral disc degeneration by regulating oxidative stress-induced ferroptosis via deubiquitinating and stabilizing Sirt3.	USP11 SIRT3	1.32e-05	2	127	2	37099926
Pubmed	Plexin/neuropilin complexes mediate repulsion by the axonal guidance signal semaphorin 3A.	PLXNA1 PLXNA2	1.32e-05	2	127	2	10781943
Pubmed	Activation of SV40 DNA replication in vitro by cellular protein phosphatase 2A.	PPP2CA PPP2CB	1.32e-05	2	127	2	2555176
Pubmed	Regulation of spindle formation by active mitogen-activated protein kinase and protein phosphatase 2A during mouse oocyte meiosis.	PPP2CA PPP2CB	1.32e-05	2	127	2	11751260
Pubmed	Differential expression of Low density lipoprotein Receptor-related Protein 1 (LRP-1) and matrix metalloproteinase-9 (MMP-9) in prostate gland: From normal to malignant lesions.	LRP1 MMP9	1.32e-05	2	127	2	27931798
Pubmed	Plasma-type gelsolin is decreased in human blood and cerebrospinal fluid after subarachnoid hemorrhage.	GSN MMP9	1.32e-05	2	127	2	21940962
Pubmed	Regulation of apoptosis by Bat3-enhanced YWK-II/APLP2 protein stability.	APLP2 BAG6	1.32e-05	2	127	2	22641691
Pubmed	Regional expression of protein phosphatase type 1 and 2A catalytic subunit isoforms in the human heart.	PPP2CA PPP2CB	1.32e-05	2	127	2	11113010
Pubmed	Lipoprotein receptor-mediated induction of matrix metalloproteinase by tissue plasminogen activator.	LRP1 MMP9	1.32e-05	2	127	2	12960961
Pubmed	Differential expression of murine CGI-105 gene in 3T3-L1 cells by adrenocorticotropic hormones.	FAHD2B FAHD2A	1.32e-05	2	127	2	15774318
Pubmed	Acceleration of Lung Regeneration by Platelet-Rich Plasma Extract through the Low-Density Lipoprotein Receptor-Related Protein 5-Tie2 Pathway.	TEK LRP5	1.32e-05	2	127	2	26091161
Pubmed	The role of protein phosphatase 2A catalytic subunit Calpha in embryogenesis: evidence from sequence analysis and localization studies.	PPP2CA PPP2CB	1.32e-05	2	127	2	10543450
Pubmed	Identification of novel TMPRSS2:ERG mechanisms in prostate cancer metastasis: involvement of MMP9 and PLXNA2.	MMP9 PLXNA2	1.32e-05	2	127	2	23708657
Pubmed	Striatins contain a noncanonical coiled coil that binds protein phosphatase 2A A subunit to form a 2:2 heterotetrameric core of striatin-interacting phosphatase and kinase (STRIPAK) complex.	STRN3 PPP2CA	1.32e-05	2	127	2	24550388
Pubmed	Extracellular matrix structure and tissue stiffness control postnatal lung development through the lipoprotein receptor-related protein 5/Tie2 signaling system.	TEK LRP5	1.32e-05	2	127	2	23841513
Pubmed	Protein phosphatase 2A in the healthy and failing heart: New insights and therapeutic opportunities.	PPP2CA PPP2CB	1.32e-05	2	127	2	34902541
Pubmed	Human liver phosphatase 2A: cDNA and amino acid sequence of two catalytic subunit isotypes.	PPP2CA PPP2CB	1.32e-05	2	127	2	2837763
Pubmed	Structure and transcriptional regulation of protein phosphatase 2A catalytic subunit genes.	PPP2CA PPP2CB	1.32e-05	2	127	2	1846293
Pubmed	PP2A regulates kinetochore-microtubule attachment during meiosis I in oocyte.	PPP2CA PPP2CB	1.32e-05	2	127	2	27096707
Pubmed	Inverse relationship between raft LRP1 localization and non-raft ERK1,2/MMP9 activation in idiopathic dilated cardiomyopathy: potential impact in ventricular remodeling.	LRP1 MMP9	1.32e-05	2	127	2	25131918
Pubmed	Plexin signaling via off-track and rho family GTPases.	PLXNA4 PLXNA1 PLXNA2	1.32e-05	13	127	3	11604131
Pubmed	The Endosome Localized Arf-GAP AGAP1 Modulates Dendritic Spine Morphology Downstream of the Neurodevelopmental Disorder Factor Dysbindin.	AGAP7P AGAP4 AGAP6	1.32e-05	13	127	3	27713690
Pubmed	Semaphorin3A, Neuropilin-1, and PlexinA1 are required for lymphatic valve formation.	PLXNA4 PLXNA1 PLXNA2	1.32e-05	13	127	3	22723296
Pubmed	Functional assembly of accessory optic system circuitry critical for compensatory eye movements.	PLXNA4 PLXNA1 PLXNA2	1.32e-05	13	127	3	25959730
Pubmed	Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.	PLXNA4 PLXNA1 PLXNA2	1.32e-05	13	127	3	10520995
Pubmed	A midline switch of receptor processing regulates commissural axon guidance in vertebrates.	PLXNA4 PLXNA1 PLXNA2	1.68e-05	14	127	3	20159958
Pubmed	GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity.	AGAP7P AGAP4 AGAP6	1.68e-05	14	127	3	22453919
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	STRN3 SLK THNSL1 RBM45 USP11 PRPF8 KLHL13 SUPT7L LRP1 TJP2 EIF3C HERC2 CTNND1 BAG6	1.94e-05	1005	127	14	19615732
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	SHANK1 RRP1B LRRK2 RUVBL2 PPP2CB CPSF1 HERC2 AGAP7P NOP2 AGAP4	2.00e-05	513	127	10	25798074
Pubmed	Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance.	FOXM1 SLK OBSCN TOR4A GTF2IRD1 COMMD4 TJP2	2.06e-05	226	127	7	31452512
Pubmed	Deletion of Sarcolemmal Membrane-Associated Protein Isoform 3 (SLMAP3) in Cardiac Progenitors Delays Embryonic Growth of Myocardium without Affecting Hippo Pathway.	STRN3 PPP2CA PPP2CB	2.10e-05	15	127	3	38474134
Pubmed	Systematic identification of factors for provirus silencing in embryonic stem cells.	PRPF8 RUVBL2 MDN1 TJP2 CPSF1 EIF3C	2.19e-05	153	127	6	26365490
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	STRN3 KIFBP SLK NAGK USP11 CARS1 SHMT1 RUVBL2 NUBP2 PPP2CA PPP2CB UBXN7 SEC23IP TJP2 MACF1 EIF3C BAG6	2.31e-05	1455	127	17	22863883
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	RRP1B INTS1 PRPF8 RUVBL2 GSN MDN1 TJP2 CPSF1 MACF1 EIF3C HERC2 CTNND1 NOP2 BAG6	2.39e-05	1024	127	14	24711643
Pubmed	Allocation of paraventricular and supraoptic neurons requires Sim1 function: a role for a Sim1 downstream gene PlexinC1.	PLXNA4 PLXNA1 PLXNA2	2.57e-05	16	127	3	17356169
Pubmed	Optic chiasm presentation of Semaphorin6D in the context of Plexin-A1 and Nr-CAM promotes retinal axon midline crossing.	PLXNA4 PLXNA1 PLXNA2	2.57e-05	16	127	3	22632726
Pubmed	Expression of the semaphorins Sema 3D and Sema 3F in the developing parathyroid and thymus.	PLXNA4 PLXNA1 PLXNA2	2.57e-05	16	127	3	18489001
Pubmed	TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6.	RET PLXNA4 PLXNA1 PLXNA2	2.68e-05	47	127	4	35462405
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	SLK RRP1B BMP2K ATG13 INTS1 RET RETSAT PPP2CA PPP2CB NCOR2 EIF3C CTNND1 MAP2K5	3.02e-05	910	127	13	36736316
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	KIFBP RRP1B USP11 SHMT1 PRPF8 NCKAP5L NCAPG2 THADA MDN1 MOGS MACF1 PNPLA8 HERC2 CTNND1 NOP2 CSPP1 BAG6	3.03e-05	1487	127	17	33957083
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	TRPM4 ATG13 OBSCN ACVR2B GTF2IRD1 TYK2 NCOR2 THADA TNRC18 POGLUT1 KCNMA1 LRP1 LRP5 MACF1 LRRC7 CTNND1 POLK	3.09e-05	1489	127	17	28611215
Pubmed	Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections.	PLXNA4 PLXNA1 PLXNA2	3.11e-05	17	127	3	11683995
Pubmed	Semaphorin signaling facilitates cleft formation in the developing salivary gland.	PLXNA4 PLXNA1 PLXNA2	3.11e-05	17	127	3	17626059
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	STRN3 KIFBP THNSL1 RRP1B BMP2K USP11 TOMM5 NUBP2 THADA MDN1 SEC23IP CPSF1 PNPLA8 HERC2 NOP2 BAG6 CYB5R1	3.27e-05	1496	127	17	32877691
Pubmed	Interactions between plexin-A2, plexin-A4, and semaphorin 6A control lamina-restricted projection of hippocampal mossy fibers.	PLXNA4 PLXNA2	3.96e-05	3	127	2	17296555
Pubmed	Heterochromatin links to centromeric protection by recruiting shugoshin.	SGO1 PPP2CA	3.96e-05	3	127	2	18716626
Pubmed	Clearance of matrix metalloproteinase-9 is dependent on low-density lipoprotein receptor-related protein-1 expression downregulated by microRNA-205 in human abdominal aortic aneurysm.	LRP1 MMP9	3.96e-05	3	127	2	26781079
Pubmed	Fyn-dependent phosphorylation of PlexinA1 and PlexinA2 at conserved tyrosines is essential for zebrafish eye development.	PLXNA1 PLXNA2	3.96e-05	3	127	2	29091353
Pubmed	Plexins promote Hedgehog signaling through their cytoplasmic GAP activity.	PLXNA1 PLXNA2	3.96e-05	3	127	2	36169302
Pubmed	The low density lipoprotein receptor-related protein modulates levels of matrix metalloproteinase 9 (MMP-9) by mediating its cellular catabolism.	LRP1 MMP9	3.96e-05	3	127	2	11279011
Pubmed	Role of transmembrane semaphorin Sema6A in oligodendrocyte differentiation and myelination.	PLXNA4 PLXNA2	3.96e-05	3	127	2	22777942
Pubmed	Activin type IIA and IIB receptors mediate Gdf11 signaling in axial vertebral patterning.	ACVR2B GDF11	3.96e-05	3	127	2	12414726
Pubmed	Tyrosine phosphorylation of protein phosphatase 2A in response to growth stimulation and v-src transformation of fibroblasts.	PPP2CA PPP2CB	3.96e-05	3	127	2	7510677
Pubmed	Microglial low-density lipoprotein receptor-related protein 1 mediates the effect of tissue-type plasminogen activator on matrix metalloproteinase-9 activity in the ischemic brain.	LRP1 MMP9	3.96e-05	3	127	2	19672275
Pubmed	A universal metabolite repair enzyme removes a strong inhibitor of the TCA cycle.	FAHD2B FAHD2A	3.96e-05	3	127	2	38287013
Pubmed	Relationship among LRP1 expression, Pyk2 phosphorylation and MMP-9 activation in left ventricular remodelling after myocardial infarction.	LRP1 MMP9	3.96e-05	3	127	2	28378397
Pubmed	Low-density lipoprotein receptor-related protein 1 promotes cancer cell migration and invasion by inducing the expression of matrix metalloproteinases 2 and 9.	LRP1 MMP9	3.96e-05	3	127	2	19176371
Pubmed	FOXM1-mediated downregulation of uPA and MMP9 by 3,3'-diindolylmethane inhibits migration and invasion of human colorectal cancer cells.	FOXM1 MMP9	3.96e-05	3	127	2	25962429
Pubmed	Differential regulation of MMP-9 and TIMP-2 expression in malignant melanoma developed in metallothionein/RET transgenic mice.	RET MMP9	3.96e-05	3	127	2	10076570
Pubmed	Identification of plexin family molecules in mice.	PLXNA1 PLXNA2	3.96e-05	3	127	2	8806646
Pubmed	Association Between eNOS, MMP-9, BAG-6 Gene Polymorphisms and Risk of Hypertensive Disorders of Pregnancy in the Northern Chinese Population.	MMP9 BAG6	3.96e-05	3	127	2	33539267
Pubmed	The catalytic subunit of protein phosphatase 2A is carboxyl-methylated in vivo.	PPP2CA PPP2CB	3.96e-05	3	127	2	8206937
Pubmed	THADA, SDHAF4, and MACF1 Gene Polymorphisms and Placental Expression in Women with Gestational Diabetes.	THADA MACF1	3.96e-05	3	127	2	36672824
Interaction	TNIK interactions	SHANK1 STRN3 DISC1 GSN PPP2CB NCOR2 KCNMA1 DCHS1 MACF1 LRRC7 HERC2 CTNND1	4.93e-06	381	126	12	int:TNIK
Interaction	LCP1 interactions	KLK10 USP11 RET GSN EBF2 KCNMA1 HERC2	7.91e-06	115	126	7	int:LCP1
Interaction	SEMA5A interactions	PLXNA4 PLXNA1 PLXNA2	8.20e-06	7	126	3	int:SEMA5A
GeneFamily	Plexins	PLXNA4 PLXNA1 PLXNA2	8.25e-06	9	85	3	683
GeneFamily	Protein phosphatase catalytic subunits\|STRIPAK complex	STRN3 PPP2CA PPP2CB	1.08e-04	20	85	3	1371
GeneFamily	ArfGAPs	AGAP7P AGAP4 AGAP6	4.94e-04	33	85	3	395
GeneFamily	Gelsolin/villins	GSN VILL	6.00e-04	8	85	2	950
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	INSRR RET TEK	8.74e-04	40	85	3	321
GeneFamily	Protein phosphatase catalytic subunits\|EF-hand domain containing	PPP2CA PPP2CB	1.65e-03	13	85	2	693
GeneFamily	Low density lipoprotein receptors	LRP1 LRP5	1.65e-03	13	85	2	634
GeneFamily	Cadherin related	RET DCHS1	2.84e-03	17	85	2	24
GeneFamily	X-linked mental retardation\|Rho GTPase activating proteins\|BAR-PH domain containing	AGAP4 AGAP6	2.84e-03	17	85	2	1291
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ARHGEF5 OBSCN PLEKHG2	3.71e-03	66	85	3	722
GeneFamily	Ankyrin repeat domain containing	SHANK1 POTEJ AGAP7P AGAP4 AGAP6	5.67e-03	242	85	5	403
GeneFamily	Ataxins\|Trinucleotide repeat containing	NCOR2 TNRC18	6.11e-03	25	85	2	775
GeneFamily	Fibronectin type III domain containing	COL7A1 INSRR OBSCN TEK	6.86e-03	160	85	4	555
Coexpression	GSE18281_SUBCAPSULAR_CORTICAL_REGION_VS_WHOLE_MEDULLA_THYMUS_UP	SHANK1 COL7A1 KLK10 ATG13 APLP2 NCAPG2 MOGS CPSF1	5.94e-06	199	127	8	M7254
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 RET GSN EBF2 TGFBR3 LRP1 RCN3	1.34e-06	192	127	7	671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 RET GSN EBF2 TGFBR3 LRP1 RCN3	1.34e-06	192	127	7	840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCell	PND01-Mesenchymal\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DPEP1 NEBL GSN TGFBR3 LRP1 MACF1 RCN3	1.59e-06	197	127	7	292b8cc3dafddf5d323fe4e3d3ea5ac61e6ce027
ToppCell	droplet-Fat-Bat-18m\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEBL INTS1 ACVR2B SGO1 NCKAP5L ETNK2	9.44e-06	170	127	6	c720d81bc29a8fd1f1249c6af408471d561f1d5d
ToppCell	droplet-Fat-Bat\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEBL INTS1 ACVR2B SGO1 NCKAP5L ETNK2	9.44e-06	170	127	6	c4ecdfc2b4710da0a5fbb20e9df02536023badb1
ToppCell	368C-Myeloid-Dendritic-pDC\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	YRDC NCAPG2 TGFBR3 VILL PLXNA4 CSPP1	9.76e-06	171	127	6	f3bf5805823d5733b58742172e7668725ce82931
ToppCell	368C-Myeloid-Dendritic-pDC\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	YRDC NCAPG2 TGFBR3 VILL PLXNA4 CSPP1	9.76e-06	171	127	6	714a0b0d0c9886fef64170cf53eb64f0d8a47280
ToppCell	P15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DPEP1 NEBL GSN TGFBR3 LRP1 MACF1	1.08e-05	174	127	6	3c47d069bd836599a8d40eae485c23d4d3487517
ToppCell	ASK452-Immune-B_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	SHMT1 TOMM5 COQ4 PLXNA4 EIF3C AGAP4	1.27e-05	179	127	6	c3cf49c069e66db16d2fce1de4c52a4c4fe7e832
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DPEP1 COL7A1 GSN EBF2 LRP1 RCN3	1.35e-05	181	127	6	3462aa1c08fbaf613b6278ab2c7a5a0940bf537d
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DPEP1 COL7A1 GSN EBF2 LRP1 RCN3	1.35e-05	181	127	6	6730e249cac55ae892cc567d9211615882f3dab4
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DPEP1 NEBL GSN LRP1 MACF1 RCN3	1.35e-05	181	127	6	091e7975badd1ffa463a8ec87908be20781ecfd6
ToppCell	P28-Mesenchymal\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DPEP1 NEBL GSN LRP1 MACF1 RCN3	1.39e-05	182	127	6	69f9d44694fe4f55a971ae0ac5dc3e7448ee78f3
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DPEP1 NEBL GSN LRP1 MACF1 RCN3	1.48e-05	184	127	6	924400f47e6b2cdf7b0d538df75857935cf0209b
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DPEP1 NEBL GSN LRP1 MACF1 RCN3	1.53e-05	185	127	6	46460e74cc613df9043f5404e7342aa13cc34873
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DPEP1 NEBL GSN LRP1 MACF1 RCN3	1.57e-05	186	127	6	88e6246172d816806a498a5c1f38e699f2f5d7c2
ToppCell	P15-Mesenchymal\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DPEP1 NEBL GSN LRP1 MACF1 RCN3	1.67e-05	188	127	6	f1ba0b661621a65c91432e62ba73531bdf18e7c1
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DPEP1 NEBL GSN LRP1 MACF1 RCN3	1.83e-05	191	127	6	509230f50568e5a8ecf08edc4d58f9e2aa96efe9
ToppCell	P07-Mesenchymal-mesenchymal_fibroblast\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DPEP1 NEBL GSN LRP1 MACF1 RCN3	1.83e-05	191	127	6	a05e9a7eb137d804570dd7d8905975d735738767
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DPEP1 NEBL GSN LRP1 MACF1 RCN3	1.83e-05	191	127	6	80484d39f34703a33b9bac09826b7a526e883cab
ToppCell	facs-Marrow-KLS-18m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RRP1B SIRT3 TFR2 MOGS TCEAL8 NOP2	1.83e-05	191	127	6	51327ba28b2e3052087fa0fc9b7c0339dc09a1e3
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DPEP1 NEBL GSN LRP1 MACF1 RCN3	1.83e-05	191	127	6	5c4e4e9de14edfae072a2a2882220a31bebf51b2
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DPEP1 NEBL GSN LRP1 MACF1 RCN3	1.83e-05	191	127	6	0b3dbbc35d9970d3c749aef16dda59886b960e3d
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 GSN TGFBR3 KCNMA1 LRP1 RCN3	1.88e-05	192	127	6	11088878043a6ff95ba1970361256a82e434b80a
ToppCell	P03-Mesenchymal-mesenchymal_fibroblast\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DPEP1 NEBL GSN LRP1 MACF1 RCN3	1.88e-05	192	127	6	e79f2253e084a9ab9afcaf7ec42a5012ade42d36
ToppCell	facs-Kidney-nan-18m-Mesenchymal-mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 NCAPG2 GSN EBF2 LRP1 RCN3	1.99e-05	194	127	6	bbc625b4cc53bb7d6254fde287258e51f9171572
ToppCell	facs-SCAT-Fat-3m-Mesenchymal\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 GSN EBF2 TGFBR3 KLHL13 RCN3	1.99e-05	194	127	6	14b614f039bc866a1348a2728a68b7d254c7748c
ToppCell	PND01-03-samps-Mesenchymal\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	DPEP1 NEBL GSN TGFBR3 LRP1 MACF1	1.99e-05	194	127	6	4f9bd0ded0dde1df885850714f29e73e992539a5
ToppCell	facs-Kidney-nan-18m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 NCAPG2 GSN EBF2 LRP1 RCN3	1.99e-05	194	127	6	fcd5e9238d299c41f0bf9693b56cd8c900d2112b
ToppCell	facs-SCAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 GSN EBF2 TGFBR3 KLHL13 RCN3	1.99e-05	194	127	6	68c7bfead1158641928cc276f599b4a79e06c73c
ToppCell	facs-MAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 GSN TGFBR3 LRP1 TCEAL8 RCN3	1.99e-05	194	127	6	f906b090f67df4cfe3498cdbb52cc0efa08e06cc
ToppCell	facs-MAT-Fat-18m-Mesenchymal\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 GSN TGFBR3 LRP1 TCEAL8 RCN3	1.99e-05	194	127	6	944cdb0403d80a10a2eea2a3516a9343dbccc32c
ToppCell	facs-GAT-Fat-18m-Mesenchymal-mesenchymal_progenitor\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 GSN EBF2 LRP1 TCEAL8 RCN3	1.99e-05	194	127	6	9709dc95fb6982b6a0467b507845d5bc17252e3e
ToppCell	facs-GAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 GSN EBF2 LRP1 TCEAL8 RCN3	1.99e-05	194	127	6	93b7a9065430740ec31fce4e8c14ffccb498591d
ToppCell	facs-GAT-Fat-18m-Mesenchymal\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 GSN EBF2 LRP1 TCEAL8 RCN3	1.99e-05	194	127	6	0d2e65b44e3f143971c2fd24c4552f042b049cfa
ToppCell	facs-SCAT-Fat-3m-Mesenchymal-mesenchymal_progenitor\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 GSN EBF2 TGFBR3 KLHL13 RCN3	1.99e-05	194	127	6	f6aeae6a1e4017e341323fd4784c9e3bae00552b
ToppCell	facs-Kidney-nan-18m-Mesenchymal-mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 NCAPG2 GSN EBF2 LRP1 RCN3	1.99e-05	194	127	6	6afc21c5fec30ab8e373e3e46ab7866204c805b6
ToppCell	facs-MAT-Fat-18m-Mesenchymal-mesenchymal_progenitor\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 GSN TGFBR3 LRP1 TCEAL8 RCN3	1.99e-05	194	127	6	85081d255fcc1e9854c0073321dd9f0feaa48866
ToppCell	facs-Brain_Myeloid-Hippocampus\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RRP1B BMP2K GSN LRP1 MACF1 HERC2	2.05e-05	195	127	6	a1478021a3ed0e779716393124ca2a7770c433b7
ToppCell	P03-Mesenchymal\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DPEP1 NEBL GSN LRP1 MACF1 RCN3	2.05e-05	195	127	6	6180309c6ae278b996fd98c57461cbc129c028ba
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DPEP1 NEBL GSN LRP1 MACF1 RCN3	2.11e-05	196	127	6	97e26622d9582b092c18ff5b7e957818f99d9631
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DPEP1 NEBL GSN LRP1 MACF1 RCN3	2.11e-05	196	127	6	f429f045ba45e24717963315832150b12a115bfa
ToppCell	severe-unassigned\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FOXM1 COL7A1 SLC26A5 NCAPG2 GSN MMP9	2.17e-05	197	127	6	70704b149b2820b8601d2495b7cd9cbe91eda262
ToppCell	Transverse-(5)_Dendritic_cell-(53)_Lymphoid_DC\|Transverse / shred on region, Cell_type, and subtype	TRPM4 BMP2K LRRK2 GSN POGLUT1 KCNMA1	2.17e-05	197	127	6	15b87fd3906d7388c271d30d0c64b1bcc490801c
ToppCell	Transverse-Dendritic_cell-Lymphoid_DC\|Transverse / Region, Cell class and subclass	TRPM4 BMP2K LRRK2 GSN POGLUT1 KCNMA1	2.17e-05	197	127	6	a58af0ea82f76f2a7abac1f62629ff20d552fc63
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FOXM1 SGO1 TOMM5 NCAPG2 COMMD4 ETNK2	2.30e-05	199	127	6	c7c501ad144ac5488d0b0496554d46616f2e01a6
ToppCell	COVID-19-Myeloid-MoAM2,_CCL18\|Myeloid / Condition, Lineage and Cell class	APLP2 LRP1 MACF1 HERC2 MMP9 RCN3	2.37e-05	200	127	6	a60346c5ea7a3dae1ad3c5dc6c6eca65b64c6888
ToppCell	severe-unassigned\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FOXM1 COL7A1 SLC26A5 FKTN TJP2	3.32e-05	128	127	5	bef9cf0078fa8498d63f0723f1fa4a3c92405e10
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DPEP1 KLK10 NEBL GSN LRRC71	8.00e-05	154	127	5	44d4d99b08216c0901e3bc32743fa0a8b85b5149
ToppCell	facs-Marrow-Granulocytes-18m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL7A1 LRRC10B PPP2CB CD6 MMP9	1.04e-04	163	127	5	7a04192710f55acf5a4681d5f09942358fdb02ff
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_1\|E16.5-samps / Age Group, Lineage, Cell class and subclass	DPEP1 NEBL GSN LRP1 MACF1	1.04e-04	163	127	5	f1ec2625b52664308968b01d8e0275e1e0751480
ToppCell	E18.5-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A\|E18.5-samps / Age Group, Lineage, Cell class and subclass	DPEP1 NEBL GSN LRP1 MACF1	1.08e-04	164	127	5	519ab4fe885dfe4c50846f346a062acc2cb44299
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	INSRR GSN EBF2 PLXNA1 RCN3	1.17e-04	167	127	5	fe3338f99f94c0dac37e3d649dfdce82e4a56022
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Basal_1\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	FOXM1 COL7A1 SIGLEC11 DNAH6 GDF11	1.27e-04	170	127	5	aabe993c9f337b1caaeb0e64626a3920579c41b7
ToppCell	ASK428-Epithelial-Secretory\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	COL7A1 KLK10 SH2D3A NCKAP5L AGAP7P	1.27e-04	170	127	5	9e275c4a70f9866f770fbdb0fe14a577287fe290
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZC3H12A BMP2K DISC1 PLXNA4 DCHS1	1.42e-04	174	127	5	7be0c6248e77f2d0260b852b01e17892f7828f1b
ToppCell	ASK452-Immune-B_cell\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	SHMT1 TOMM5 COQ4 PLXNA4 AGAP4	1.42e-04	174	127	5	69723f5666abc3af5f0431901a60246c9915ef81
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_D3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	LRRC10B SHMT1 KLHL13 ETNK2 DNAH6	1.42e-04	174	127	5	e5f12831187140e84b9a49e93b2376b9fefb1aec
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TEK NACAD GSN DCHS1 LRP1	1.42e-04	174	127	5	1d157f7a919c8246e83d8060d2a0017c6c781ef3
ToppCell	Children_(3_yrs)-Immune-enucleated_erythrocyte\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SEMA4F COL7A1 THNSL1 LRRC4 NACAD	1.46e-04	175	127	5	36cb3c8116bd467ee5da0630d8b3d3e4afcc2ded
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WDR81 GTF2IRD1 TYK2 TNRC18 GDF11	1.46e-04	175	127	5	bb898796662b97f7459b7dda7cecf6a9bde8b055
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAMTS3 ITGA10 CCER1 VILL KCNMA1	1.50e-04	176	127	5	77c3da2eaa072a6baefb5087fd07ec18c5e271cd
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_D3\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	LRRC10B SHMT1 KLHL13 ETNK2 DNAH6	1.50e-04	176	127	5	bd5c85b3a4fb88ffe156599f6d224aa7664a513a
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SHANK1 DPEP1 COL7A1 EBF2 RCN3	1.58e-04	178	127	5	27497dbfcf9bb4dd0bf7caa0bd78c7e85f5c18ee
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SHANK1 DPEP1 COL7A1 EBF2 RCN3	1.58e-04	178	127	5	d348a9550db940d204706529759dc51e30506b5f
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_3\|356C / Donor, Lineage, Cell class and subclass (all cells)	DISC1 AOC2 SYCE1L EIF3C GDF11	1.62e-04	179	127	5	f378307eb20f002450c748b7be2289d6db2fcbcb
ToppCell	10x5'-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages\|lymph-node_spleen / Manually curated celltypes from each tissue	TEK KCNMA1 LRP1 SIGLEC11 MMP9	1.66e-04	180	127	5	7be7d7a6906fff6dbdecd9cb013d855aba4eda2a
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NEBL ADAMTS3 PLXNA4 LRP1 LRRC7	1.66e-04	180	127	5	08ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell	metastatic_Lymph_Node-Myeloid_cells-CD207+CD1a+_LCs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	TRPM4 GTF2IRD1 GSN RCN3 CYB5R1	1.66e-04	180	127	5	289f8c4b53ffd164fee1f459a9315c0deb5f76d0
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-DN3_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA4F ARHGEF5 ITGA10 ACVR2B SUPT7L	1.70e-04	181	127	5	e2d03115a87f45a7ddd3ade6b9ac3843639bd41a
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA4F ARHGEF5 ITGA10 ACVR2B SUPT7L	1.70e-04	181	127	5	d8d11ef83c4b8b6a6f5c8728e03059e45a8ad264
ToppCell	E18.5-samps-Mesenchymal-Matrix_fibroblast\|E18.5-samps / Age Group, Lineage, Cell class and subclass	DPEP1 NEBL GSN LRP1 MACF1	1.75e-04	182	127	5	ceb37c214662a48efb56ab0d015977c6fab478b0
ToppCell	facs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 NEBL GSN TGFBR3 LRP1	1.75e-04	182	127	5	c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCell	P28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DPEP1 NEBL GSN LRP1 MACF1	1.75e-04	182	127	5	19c5e3a9d9b3728303b682102e276adfe93aa759
ToppCell	facs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 NEBL GSN TGFBR3 LRP1	1.75e-04	182	127	5	dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GSN EBF2 TGFBR3 LRP1 RCN3	1.75e-04	182	127	5	d179b5deb07c20d49eb6c58d5a65904f8921de3a
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Proliferating_Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXM1 RBM45 INTS1 SGO1 NCAPG2	1.79e-04	183	127	5	42dc31d587fbb9724b2f0be5ee8ed77233f67b86
ToppCell	LPS-IL1RA\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIFBP CARS1 TEK CX3CL1 PLXNA2	1.84e-04	184	127	5	c066c2ec4f0f1d6eb183fca5c7bb0cd45c9950dc
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAMTS3 SLC1A2 GSN TGFBR3 LRP1	1.89e-04	185	127	5	9faa35ceb89ccd2979072286f063687c9f846ce3
ToppCell	droplet-Fat-Scat-21m-Mesenchymal-Cd34+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 GSN EBF2 KLHL13 RCN3	1.89e-04	185	127	5	01bbe1e09f9ccae837a03ea2cdd168fa10800942
ToppCell	facs-Limb_Muscle-Muscle_Diaphragm-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 GSN LRP1 TCEAL8 RCN3	1.93e-04	186	127	5	a66da8453bb78f7e9f5f59452b3c50ae679d83c3
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-24m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 GSN EBF2 LRP1 RCN3	1.93e-04	186	127	5	ff6ccfdf2509f96caa10281c29a95b432f6c6dcc
ToppCell	facs-Marrow-KLS-24m-Hematologic-MPP_Fraction_A_+_HSC\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN SIRT3 TFR2 TGFBR3 TCEAL8	1.93e-04	186	127	5	f14722ecc832794dc267bf3f9b8a13274c3addc1
ToppCell	facs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 GSN EBF2 LRP1 RCN3	1.93e-04	186	127	5	a7ab70b049742dfe7ee30557031bfac6412edf52
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	DISC1 AOC2 SYCE1L EIF3C GDF11	1.98e-04	187	127	5	c8278525b3e1d3f3f4defcaf109cce22dd2e157a
ToppCell	facs-Bladder-nan-24m-Epithelial-bladder_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 GSN EBF2 LRP1 RCN3	1.98e-04	187	127	5	2c145e9d11424939dd99012a8cedf5d998b966e9
ToppCell	droplet-Fat-Scat-21m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 GSN EBF2 KLHL13 RCN3	2.03e-04	188	127	5	e54e09d34e263d5709c337914809e61e74e20591
ToppCell	droplet-Fat-Scat-21m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 GSN EBF2 KLHL13 RCN3	2.03e-04	188	127	5	7fc9810ab14354cb512e2b1285562009c10203f5
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 GSN EBF2 KLHL13 LRP1	2.03e-04	188	127	5	7191087d8754f5e8700e3d744cd920ee26db1e57
ToppCell	Fibroblast-A\|World / shred on cell class and cell subclass (v4)	DPEP1 NEBL GSN MACF1 RCN3	2.03e-04	188	127	5	6740bed5fb8f45b6eea17041894b804214c2a4ae
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	THNSL1 ATG13 DISC1 LRRK2 TNRC18	2.03e-04	188	127	5	c2febf9fd4632af1f922067c3a30e5c50f75f480
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 GSN EBF2 LRP1 RCN3	2.08e-04	189	127	5	bc54ffd7bd1627a36747a80ce5139e4a69928400
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 GSN LRP1 MACF1 RCN3	2.08e-04	189	127	5	324c81285c51f4f8bb1aef428b18fe2c549c2c11
ToppCell	E18.5-samps-Mesenchymal\|E18.5-samps / Age Group, Lineage, Cell class and subclass	NEBL TGFBR3 LRP1 MACF1 RCN3	2.08e-04	189	127	5	0c18d3de4720759cf802eefb4d0ddde2a9246a1a
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TGFBR3 KLHL13 PLXNA4 KCNMA1 LRP1	2.08e-04	189	127	5	45e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BMP2K DISC1 KCNMA1 LRP1 RCN3	2.14e-04	190	127	5	788ff9d8888d2dd25b7e1d7e0e5d57751ce86f19
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 GSN EBF2 LRP1 RCN3	2.14e-04	190	127	5	f3ca94a31a35eed5fecf3c4b8c957e1bc4150158
ToppCell	droplet-Limb_Muscle-nan-24m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 GSN EBF2 LRP1 RCN3	2.14e-04	190	127	5	ad0f5605db6b694445ec9bd5dc8d2d834358c0f9
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPEP1 GSN EBF2 LRP1 RCN3	2.14e-04	190	127	5	c2cd1eb674162ee40502c3380b7245c85079c7ce
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SHMT1 SGO1 NCAPG2 LRRC7 PLXNA2	2.14e-04	190	127	5	e83fa8b711aa79a1767818474f1c193b674b1c31
Drug	CP-320650-01 [172079-28-6]; Up 200; 1uM; PC3; HT_HG-U133A	COL7A1 NEBL DISC1 AOC2 APLP2 COMMD4 KCNMA1 LRP1 CPSF1	1.69e-06	199	126	9	4560_UP
Drug	Palmatine chloride [3486-67-7]; Down 200; 10.4uM; PC3; HT_HG-U133A	STRN3 COL7A1 NEBL ACVR2B NCOR2 MLH3 CD6 MAP2K5 RAB11FIP3	1.77e-06	200	126	9	6612_DN
Disease	Headache	ATG13 TGFBR3 LRP1 TJP2 MACF1	6.18e-06	64	119	5	HP_0002315
Disease	cerebral palsy (implicated_via_orthology)	AGAP7P AGAP4 AGAP6	7.52e-06	10	119	3	DOID:1969 (implicated_via_orthology)
Disease	heart valve disease (is_marker_for)	LRP5 MMP9	4.83e-05	3	119	2	DOID:4079 (is_marker_for)
Disease	Ovarian Serous Adenocarcinoma	SLK LRRK2 TEK	1.07e-04	23	119	3	C1335177
Disease	stem Cell Growth Factor-beta measurement	SHANK1 RAB11FIP3	1.60e-04	5	119	2	EFO_0802090
Disease	amyotrophic lateral sclerosis (is_marker_for)	LRRK2 SLC1A2 MMP9	2.16e-04	29	119	3	DOID:332 (is_marker_for)
Disease	microcephaly (implicated_via_orthology)	CARS1 WDR81 ETNK2	2.91e-04	32	119	3	DOID:10907 (implicated_via_orthology)
Disease	stem cell growth factor-alpha measurement	SHANK1 RAB11FIP3	3.34e-04	7	119	2	EFO_0020754
Disease	Malignant neoplasm of breast	FOXM1 COL7A1 KLK10 SH2D3A OBSCN SHMT1 TEK GSN FKTN MACF1 LRRC7 HERC2 MMP9	4.04e-04	1074	119	13	C0006142
Disease	Developmental Coordination Disorder	SHANK1 DISC1	4.44e-04	8	119	2	C0011757
Disease	Motor Skills Disorders	SHANK1 DISC1	4.44e-04	8	119	2	C0026613
Disease	polymyositis (is_marker_for)	MMP9 CX3CL1	8.66e-04	11	119	2	DOID:0080745 (is_marker_for)
Disease	human Chorionic Gonadotropin measurement	TRPM4 RUVBL2	1.22e-03	13	119	2	EFO_0008156
Disease	Williams-Beuren syndrome (implicated_via_orthology)	GTF2IRD1 NOP2	1.64e-03	15	119	2	DOID:1928 (implicated_via_orthology)
Disease	pre-eclampsia (is_marker_for)	ACVR2B GSN MMP9	1.68e-03	58	119	3	DOID:10591 (is_marker_for)
Disease	testosterone measurement	FOXM1 ADAMTS3 WDR81 GTF2IRD1 RUVBL2 TYK2 EBF2 NCOR2 THADA COMMD4 SEC23IP LRP5 MACF1	1.93e-03	1275	119	13	EFO_0004908
Disease	Muscle hypotonia	INTS1 PPP2CA	2.11e-03	17	119	2	C0026827
Disease	dermatomyositis (is_marker_for)	MMP9 CX3CL1	2.11e-03	17	119	2	DOID:10223 (is_marker_for)
Disease	Colorectal Carcinoma	SHANK1 DPEP1 COL7A1 OBSCN RET LRRC4 MLH3 DCHS1 LRP1	2.20e-03	702	119	9	C0009402
Disease	pulmonary hypertension (is_marker_for)	TEK MMP9 CX3CL1	2.23e-03	64	119	3	DOID:6432 (is_marker_for)
Disease	skin sensitivity to sun	DPEP1 HERC2	2.64e-03	19	119	2	EFO_0004795
Disease	rheumatoid arthritis (is_marker_for)	LRRK2 MMP9 CX3CL1	2.76e-03	69	119	3	DOID:7148 (is_marker_for)
Disease	age-related macular degeneration, COVID-19	TYK2 MMP9 BAG6	2.76e-03	69	119	3	EFO_0001365, MONDO_0100096
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	SHANK1 LRRK2 TEK KCNMA1	3.09e-03	148	119	4	C0279702
Disease	osteoarthritis, hip, osteoarthritis, knee, total joint arthroplasty	NCOR2 KCNMA1	3.22e-03	21	119	2	EFO_0004616, EFO_0010726, EFO_1000786
Disease	gastric ulcer (biomarker_via_orthology)	TEK MMP9	3.22e-03	21	119	2	DOID:10808 (biomarker_via_orthology)
Disease	migraine disorder	TGFBR3 NCOR2 THADA LRP1 TJP2 MACF1	3.32e-03	357	119	6	MONDO_0005277
Disease	Non-Small Cell Lung Carcinoma	FOXM1 COL7A1 RET MMP9	3.73e-03	156	119	4	C0007131

Protein segments in the cluster

Peptide	Gene	Start	Entry
HVRDREMPEALEFNP	AGAP4	66	Q96P64
FERTPPIMGIIIDHF	ATG13	201	O75143
RLQVVLEHMPVGPDA	BAG6	921	P46379
LEHMPVGPDAILRYV	BAG6	926	P46379
GPETNIPRELMLHEV	COQ10B	221	Q9H8M1
PSFVSMEDVRIHEPL	ARHGEF5	711	Q12774
GIVFLETSERMEPPH	A4GNT	51	Q9UNA3
RHPGDPERLAKEMLL	EBF2	356	Q9HAK2
DTEPENLGHRPLLMD	BMP2K	776	Q9NSY1
GDDTHTPLRMEPRLL	DISC1	426	Q9NRI5
EQRGEEFHLPLEMPL	CCER1	351	Q8TC90
HVRDREMPEALEFNP	AGAP6	66	Q5VW22
MLGRHIVAVLPEIDP	NAGK	241	Q9UJ70
VPLDPALMRTLEEGH	NUBP2	226	Q9Y5Y2
FLHPEEFPHMRDIVI	RCN3	191	Q96D15
EALGHEPRVNMFPFV	RBM45	211	Q8IUH3
DAMEEPDHGALLLLP	RAB11FIP3	356	O75154
LLMAHFDVVPAPEEG	PM20D1	121	Q6GTS8
HGIVEVDPMLTPEER	APLP2	726	Q06481
PLGIHIPLESDMERA	AOC2	606	O75106
QMPPLEEGLEELHAS	CD6	521	P30203
VEHFILEVIGRLPDM	POGLUT1	111	Q8NBL1
DRMFPGVPLDTHDVF	MMP9	651	P14780
PVHPLDVMADARALE	NCOR2	1486	Q9Y618
EFGTMRPLDREVEPA	DCHS1	1806	Q96JQ0
HELGLDEPLMTPLRE	OGFOD2	181	Q6N063
PDLLHQLMVEADVPG	KLHL33	186	A6NCF5
PEHPALEQLLVVMDR	MDN1	3746	Q9NU22
MRHDPLLIPGNDQID	KCNMA1	786	Q12791
GDMVPSIHRPLEQLE	NCKAP5L	706	Q9HCH0
EFFGIPMEILPHVRS	GK3P	221	Q14409
PLGPADAMELADHLV	INTS1	666	Q8N201
EMRIGELHPSLAETP	LRRC7	636	Q96NW7
MFPPEHPVEEVGRLL	HERC2	1426	O95714
DEPHAIVVDPLRGTM	LRP1	4001	Q07954
EDLDEPRAIALHPVM	LRP5	456	O75197
LRLHPMAIDGPVDSF	CPSF1	961	Q10570
MQGVALEPEHIREPR	ETNK2	156	Q9NVF9
VLFPGIEDHPVLKEM	PLXNA1	1331	Q9UIW2
AMRVLFPGIEDHPVL	PLXNA2	1321	O75051
TMRVLFPGIEDHPVL	PLXNA4	1321	Q9HCM2
GRPSMLPLADIDHLE	MLH3	1396	Q9UHC1
ERPAPEELMGHPFIV	MAP2K5	406	Q13163
FSVAPRHFEEMIPPE	CSPP1	466	Q1MSJ5
MVPEEPEDLRGHLES	FGF19	171	O95750
LEPVEHRDGKVFMPG	LRRC71	456	Q8N4P6
EELEMSGNHFPEIRP	LRRC4	221	Q9HBW1
RAILHFIVPGMPEES	LRRK2	506	Q5S007
FEEFPPALLRMGRLH	LRRC10B	171	A6NIK2
DMRLVQFRAPHLVGP	FAHD2A	26	Q96GK7
RALDRLQEVPHEGPM	PPP2CB	181	P62714
RALDRLQEVPHEGPM	PPP2CA	181	P67775
RDIMEIEGEPAPDHR	MACF1	4066	Q9UPN3
LLPVAHMLEVGDPDD	MOGS	516	Q13724
ASDVHEQLVPPRMLE	OBSCN	5361	Q5VST9
LPGLREPLMEHRVLE	OBSCN	6911	Q5VST9
LLGPPESMREHVVAA	EIF3C	726	Q99613
SEMEELAEHGIFLPP	CFAP298	46	P57076
MFDIPPGARHVLIQE	ADAMTS3	731	O15072
NLPLIDDPEIFGMHE	DNAH6	3806	Q9C0G6
LMPGDTDDAFPVHRV	KLHL13	96	Q9P2N7
DMRLVQFRAPHLVGP	FAHD2B	26	Q6P2I3
HPDVVMLIAFPGDIL	SLC1A2	71	P43004
PGAEGLHPFMELRVL	GDF11	276	O95390
RALREELGITAPPMH	COQ4	246	Q9Y3A0
HVRDREMPEALEFNP	AGAP7P	66	Q5VUJ5
EEPMVHLRLEVAAAP	COMMD4	151	Q9H0A8
GLEVLIPKDPMHFVE	FKTN	226	O75072
GHRLFPPRMALEDEF	ITGA10	406	O75578
VIFEMPHLRDVALPA	INSRR	116	P14616
EEEIQPGEEMPHLAR	FOXM1	461	Q08050
HVPGVMVLLVDEPLR	COL7A1	1156	Q02388
EARPNSMVVEHPEFL	GSN	46	P06396
EEEGEPRITRSFMPH	CCDC168	4711	Q8NDH2
MHPEELFVVGLPEGI	GTF2IRD1	596	Q9UHL9
DTEPENLGHRPLLMD	BMP2KL	31	Q5H9B9
IMRDSPVIDGHNDLP	DPEP1	26	P16444
PELPEVIAMLGFRLD	CTNND1	366	O60716
FPEHIGEDVLRPAML	KIFBP	531	Q96EK5
LVEPHGRIMGLDLPD	SHMT1	131	P34896
EEVHIMLDGLLPPDT	PNPLA8	691	Q9NP80
MPREEAAEHIPLLFF	RETSAT	426	Q6NUM9
IIPGVLFIDEVHMLD	RUVBL2	291	Q9Y230
MIADLGDDELPHIPS	STRN3	376	Q13033
MHRLTVEGADFVPDP	THADA	421	Q6YHU6
AARALVPFVMIDHIP	THADA	1366	Q6YHU6
RAHREMLESAVLPPE	RRP1B	481	Q14684
LGITLIEMAEIEPPH	SLK	221	Q9H2G2
GDFHRDMEALNVLPP	CARS1	221	P49589
PVRHLDPEEMIRGVD	TCEAL8	66	Q8IYN2
EKPMHLEIEDSGPLI	GTF3C6	181	Q969F1
PDRVLTFIRDHPLMD	SEMA4F	401	O95754
RFMPPGDNVHTVILD	SLC26A5	631	P58743
LMLLEHGTDPNIPDE	POTEJ	186	P0CG39
VGFLDPLVNMHIPEN	SGO1	226	Q5FBB7
RPFPGEDIRADVMAD	SIRT3	261	Q9NTG7
PDGEMPQVDHLVFVV	SEC23IP	436	Q9Y6Y8
PFPDVMEQVFHEVGI	SUPT7L	211	O94864
ERRLHSPPEVEGAMA	SYCE1L	176	A8MT33
FVTADMIREHLPAPG	CYB5R1	256	Q9UHQ9
MIREHLPAPGDDVLV	CYB5R1	261	Q9UHQ9
PVMALAPQEHERILD	NOP2	376	P46087
RHLQGVEFEMRPPLL	SHANK1	1981	Q9Y566
MLPFEEEIGQHPSLE	ACVR2B	411	Q13705
EAFPIRDPNLHAIEM	NCAPG2	356	Q86XI2
KGMLDPLEVHLLDFP	PRPF8	1866	Q6P2Q9
SHMLREVLDGPVVDP	TNRC18	1426	O15417
RPVVLFGPIADIAME	TJP2	731	Q9UDY2
PHLVEAVMGRFPQLL	ZC3H12A	566	Q5D1E8
EDAMDGLPSHRPVIE	PYROXD2	421	Q8N2H3
LPHVAPMVRLLEGEE	SH2D3A	471	Q9BRG2
IDADFPHPLRLRLMG	POLK	496	Q9UBT6
MFRIEGLAPKLDPEE	TOMM5	1	Q8N4H5
HPADIPAARLGEMIE	THNSL1	301	Q8IYQ7
PHEPITIGRDFEALM	TEK	51	Q02763
LMHQAVEDLPEGVDP	VILL	801	O15195
HAGAREEVVMVPFPV	RET	246	P07949
DDVELMPRPLLDELH	TOR4A	266	Q9NXH8
HQGLPAVDSEILEMP	UBXN7	381	O94888
GLEMDERGPSPLHVL	PLEKHG2	601	Q9H7P9
ETLAHFCPMELRGPE	TFR2	46	Q9UP52
MLFGHPLLVSVPRDR	USP11	611	P51784
LELPPIQMEHEGEFT	SIGLEC11	421	Q96RL6
AELRPPDVGHVLRML	TRPM4	496	Q8TD43
IFRSIHPDMPDLDVP	WDR81	501	Q562E7
EMGDEEVHTIPPELR	TGFBR3	361	Q03167
AEEPIHATMDPQRLG	CX3CL1	311	P78423
HEVAPPRLVMSIRDG	TYK2	436	P29597
FTPLVGIRIPDHAFM	YRDC	166	Q86U90
GPILPRRTDEHDLML	KLK10	126	O43240
MPGEAARAELLLPEA	NACAD	1	O15069
PHIVEMDRRPGIIVD	NEBL	826	O76041