Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	sodium ion binding	SCN1A SCN2A SCN3A SCN9A	2.52e-06	14	145	4	GO:0031402
GeneOntologyMolecularFunction	voltage-gated sodium channel activity	SCN1A SCN2A SCN3A SCN9A	3.52e-05	26	145	4	GO:0005248
GeneOntologyMolecularFunction	alkali metal ion binding	SCN1A SCN2A SCN3A SCN9A	3.52e-05	26	145	4	GO:0031420
GeneOntologyCellularComponent	voltage-gated sodium channel complex	SCN1A SCN2A SCN3A SCN9A	4.93e-06	17	145	4	GO:0001518
GeneOntologyCellularComponent	sodium channel complex	SCN1A SCN2A SCN3A SCN9A	4.61e-05	29	145	4	GO:0034706
GeneOntologyCellularComponent	external encapsulating structure	NPHS1 CD248 LAMB3 LINGO3 PKHD1L1 LRIG3 CLEC14A VWA5A NCAN ZP4 MMP19 AGRN OTOG IMPG2	2.00e-04	658	145	14	GO:0030312
HumanPheno	Photosensitive myoclonic seizure	SCN1A SCN2A SCN9A	3.50e-05	8	45	3	HP:0001327
HumanPheno	Cyanotic episode	SCN1A SCN2A SCN9A	3.50e-05	8	45	3	HP:0200048
Domain	Na_trans_cytopl	SCN1A SCN2A SCN3A SCN9A	4.48e-08	6	140	4	PF11933
Domain	Na_trans_cytopl	SCN1A SCN2A SCN3A SCN9A	4.48e-08	6	140	4	IPR024583
Domain	Na_channel_asu	SCN1A SCN2A SCN3A SCN9A	6.13e-07	10	140	4	IPR001696
Domain	Na_trans_assoc	SCN1A SCN2A SCN3A SCN9A	6.13e-07	10	140	4	IPR010526
Domain	Na_trans_assoc	SCN1A SCN2A SCN3A SCN9A	6.13e-07	10	140	4	PF06512
Domain	EGF_3	CD248 ADAM12 CELSR1 CELSR3 CLEC14A NCAN LRP4 ASTN2 AGRN OTOG IMPG2	1.62e-06	235	140	11	PS50026
Domain	EGF_1	CD248 LAMB3 ADAM12 CELSR1 CELSR3 CLEC14A NCAN LRP4 ASTN2 AGRN IMPG2	3.56e-06	255	140	11	PS00022
Domain	EGF_2	CD248 LAMB3 ADAM12 CELSR1 CELSR3 CLEC14A NCAN LRP4 ASTN2 AGRN IMPG2	5.14e-06	265	140	11	PS01186
Domain	EGF-like_dom	CD248 ADAM12 CELSR1 CELSR3 CLEC14A NCAN LRP4 AGRN OTOG IMPG2	1.86e-05	249	140	10	IPR000742
Domain	EGF-like_CS	CD248 LAMB3 ADAM12 CELSR1 CELSR3 CLEC14A NCAN LRP4 AGRN IMPG2	2.79e-05	261	140	10	IPR013032
Domain	IQ	ADGB SCN1A SCN2A SCN3A SCN9A MYO18B	3.26e-05	81	140	6	SM00015
Domain	HRM	ADGRB3 CELSR1 CELSR3 ADGRA3	5.38e-05	28	140	4	PF02793
Domain	IQ_motif_EF-hand-BS	ADGB SCN1A SCN2A SCN3A SCN9A MYO18B	5.92e-05	90	140	6	IPR000048
Domain	GAIN_dom_N	ADGRB3 CELSR1 CELSR3	6.51e-05	11	140	3	IPR032471
Domain	GAIN	ADGRB3 CELSR1 CELSR3	6.51e-05	11	140	3	PF16489
Domain	IQ	ADGB SCN1A SCN2A SCN3A SCN9A MYO18B	7.11e-05	93	140	6	PS50096
Domain	EGF_LAM_2	LAMB3 CELSR1 CELSR3 AGRN	7.12e-05	30	140	4	PS50027
Domain	EGF_LAM_1	LAMB3 CELSR1 CELSR3 AGRN	7.12e-05	30	140	4	PS01248
Domain	Ig_I-set	NPHS1 SDK2 DSCAM SPEG IGDCC3 LINGO3 LRIG3 ADGRA3	9.41e-05	190	140	8	IPR013098
Domain	I-set	NPHS1 SDK2 DSCAM SPEG IGDCC3 LINGO3 LRIG3 ADGRA3	9.41e-05	190	140	8	PF07679
Domain	GPS	ADGRB3 CELSR1 CELSR3 ADGRA3	1.18e-04	34	140	4	SM00303
Domain	EGF_Lam	LAMB3 CELSR1 CELSR3 AGRN	1.32e-04	35	140	4	SM00180
Domain	GPS	ADGRB3 CELSR1 CELSR3 ADGRA3	1.32e-04	35	140	4	PF01825
Domain	Laminin_EGF	LAMB3 CELSR1 CELSR3 AGRN	1.32e-04	35	140	4	PF00053
Domain	SEA	MUC16 AGRN IMPG2	1.41e-04	14	140	3	SM00200
Domain	EGF-type_Asp/Asn_hydroxyl_site	CD248 CELSR1 CELSR3 CLEC14A NCAN LRP4	1.47e-04	106	140	6	IPR000152
Domain	GPS	ADGRB3 CELSR1 CELSR3 ADGRA3	1.48e-04	36	140	4	PS50221
Domain	GPS	ADGRB3 CELSR1 CELSR3 ADGRA3	1.65e-04	37	140	4	IPR000203
Domain	GYF	GIGYF1 GIGYF2	1.67e-04	3	140	2	PS50829
Domain	GYF	GIGYF1 GIGYF2	1.67e-04	3	140	2	SM00444
Domain	GYF	GIGYF1 GIGYF2	1.67e-04	3	140	2	PF02213
Domain	-	GIGYF1 GIGYF2	1.67e-04	3	140	2	3.30.1490.40
Domain	-	MUC16 AGRN IMPG2	1.76e-04	15	140	3	3.30.70.960
Domain	Laminin_EGF	LAMB3 CELSR1 CELSR3 AGRN	1.83e-04	38	140	4	IPR002049
Domain	GPCR_2_extracellular_dom	ADGRB3 CELSR1 CELSR3 ADGRA3	2.24e-04	40	140	4	IPR001879
Domain	G_PROTEIN_RECEP_F2_1	ADGRB3 CELSR1 CELSR3 ADGRA3	2.24e-04	40	140	4	PS00649
Domain	G_PROTEIN_RECEP_F2_3	ADGRB3 CELSR1 CELSR3 ADGRA3	2.24e-04	40	140	4	PS50227
Domain	EGF_CA	CD248 CELSR1 CELSR3 NCAN LRP4 AGRN	3.16e-04	122	140	6	SM00179
Domain	P5-ATPase	ATP13A4 ATP13A5	3.31e-04	4	140	2	PF12409
Domain	GYF	GIGYF1 GIGYF2	3.31e-04	4	140	2	IPR003169
Domain	EGF-like_Ca-bd_dom	CD248 CELSR1 CELSR3 NCAN LRP4 AGRN	3.45e-04	124	140	6	IPR001881
Domain	EGF	CD248 CELSR1 CELSR3 NCAN LRP4 AGRN	3.76e-04	126	140	6	PF00008
Domain	EGF	CD248 CELSR1 CELSR3 CLEC14A NCAN BRINP2 LRP4 AGRN	4.01e-04	235	140	8	SM00181
Domain	IGc2	NPHS1 SDK2 DSCAM SPEG IGDCC3 LINGO3 LRIG3 IL1R2	4.01e-04	235	140	8	SM00408
Domain	Ig_sub2	NPHS1 SDK2 DSCAM SPEG IGDCC3 LINGO3 LRIG3 IL1R2	4.01e-04	235	140	8	IPR003598
Domain	7tm_2	ADGRB3 CELSR1 CELSR3 ADGRA3	5.33e-04	50	140	4	PF00002
Domain	G_PROTEIN_RECEP_F2_2	ADGRB3 CELSR1 CELSR3 ADGRA3	5.33e-04	50	140	4	PS00650
Domain	Groucho_enhance	TLE2 TLE4	5.50e-04	5	140	2	IPR009146
Domain	TLE_N	TLE2 TLE4	5.50e-04	5	140	2	PF03920
Domain	P-type_TPase_V	ATP13A4 ATP13A5	5.50e-04	5	140	2	IPR006544
Domain	Groucho/TLE_N	TLE2 TLE4	5.50e-04	5	140	2	IPR005617
Domain	Tet-R_TetA/multi-R_MdtG	MFSD14A MFSD14B	5.50e-04	5	140	2	IPR001958
Domain	SEA	MUC16 AGRN IMPG2	5.72e-04	22	140	3	PF01390
Domain	SEA	MUC16 AGRN IMPG2	6.54e-04	23	140	3	PS50024
Domain	SEA_dom	MUC16 AGRN IMPG2	6.54e-04	23	140	3	IPR000082
Domain	HormR	ADGRB3 CELSR1 CELSR3	8.40e-04	25	140	3	SM00008
Domain	Channel_four-helix_dom	SCN1A SCN2A SCN3A SCN9A	8.78e-04	57	140	4	IPR027359
Domain	-	SCN1A SCN2A SCN3A SCN9A	8.78e-04	57	140	4	1.20.120.350
Domain	ASX_HYDROXYL	CELSR1 CELSR3 CLEC14A NCAN LRP4	9.37e-04	100	140	5	PS00010
Domain	GPCR_2_secretin-like	ADGRB3 CELSR1 CELSR3 ADGRA3	1.07e-03	60	140	4	IPR000832
Domain	GPCR_2-like	ADGRB3 CELSR1 CELSR3 ADGRA3	1.07e-03	60	140	4	IPR017981
Domain	G_PROTEIN_RECEP_F2_4	ADGRB3 CELSR1 CELSR3 ADGRA3	1.13e-03	61	140	4	PS50261
Domain	IG	NPHS1 SDK2 DSCAM SPEG IGDCC3 LINGO3 LRIG3 IL1R2 NCAN ADGRA3	1.29e-03	421	140	10	SM00409
Domain	Ig_sub	NPHS1 SDK2 DSCAM SPEG IGDCC3 LINGO3 LRIG3 IL1R2 NCAN ADGRA3	1.29e-03	421	140	10	IPR003599
Domain	-	NPHS1 SDK2 DSCAM SPEG IGDCC3 LINGO3 PKHD1L1 LRIG3 IL1R2 NCAN ASTN2 ADGRA3 SECTM1	1.46e-03	663	140	13	2.60.40.10
Domain	WD40_repeat_CS	TEP1 SEC31B AAAS GTF3C2 TLE2 TLE4	1.49e-03	164	140	6	IPR019775
Domain	WD40_repeat_dom	TEP1 SEC31B AAAS GTF3C2 ARHGEF10 TLE2 NBEAL2 TLE4	1.82e-03	297	140	8	IPR017986
Domain	IQ	SCN1A SCN3A SCN9A MYO18B	1.99e-03	71	140	4	PF00612
Domain	Ig-like_fold	NPHS1 SDK2 DSCAM SPEG IGDCC3 LINGO3 PKHD1L1 LRIG3 IL1R2 NCAN ASTN2 ADGRA3 SECTM1	2.53e-03	706	140	13	IPR013783
Domain	FN3	NPHS1 SDK2 DSCAM SPEG IGDCC3 ASTN2	2.73e-03	185	140	6	SM00060
Domain	LAM_G_DOMAIN	CELSR1 CELSR3 AGRN	2.87e-03	38	140	3	PS50025
Domain	MACPF	BRINP2 ASTN2	2.94e-03	11	140	2	PF01823
Domain	ig	NPHS1 SDK2 DSCAM IGDCC3 IL1R2 ADGRA3	3.12e-03	190	140	6	PF00047
Domain	Immunoglobulin	NPHS1 SDK2 DSCAM IGDCC3 IL1R2 ADGRA3	3.12e-03	190	140	6	IPR013151
Domain	WD40	TEP1 SEC31B AAAS GTF3C2 TLE2 NBEAL2 TLE4	3.42e-03	259	140	7	PF00400
Domain	MACPF	BRINP2 ASTN2	3.51e-03	12	140	2	IPR020864
Domain	MACPF	BRINP2 ASTN2	3.51e-03	12	140	2	SM00457
Domain	-	TEP1 SEC31B AAAS GTF3C2 ARHGEF10 TLE2 NBEAL2 TLE4	3.67e-03	333	140	8	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	TEP1 SEC31B AAAS GTF3C2 ARHGEF10 TLE2 NBEAL2 TLE4	3.80e-03	335	140	8	IPR015943
Domain	FN3	NPHS1 SDK2 DSCAM SPEG IGDCC3 ASTN2	3.91e-03	199	140	6	PS50853
Domain	IG_LIKE	NPHS1 SDK2 DSCAM SPEG IGDCC3 LINGO3 LRIG3 IL1R2 NCAN ADGRA3	3.94e-03	491	140	10	PS50835
Domain	WD40	TEP1 SEC31B AAAS GTF3C2 TLE2 NBEAL2 TLE4	4.13e-03	268	140	7	SM00320
Domain	LamG	CELSR1 CELSR3 AGRN	4.36e-03	44	140	3	SM00282
Domain	WD40_repeat	TEP1 SEC31B AAAS GTF3C2 TLE2 NBEAL2 TLE4	4.47e-03	272	140	7	IPR001680
Domain	Ig-like_dom	NPHS1 SDK2 DSCAM SPEG IGDCC3 LINGO3 LRIG3 IL1R2 NCAN ADGRA3	4.66e-03	503	140	10	IPR007110
Domain	Cys-rich_flank_reg_C	LINGO3 LRG1 LRIG3 ADGRA3	4.70e-03	90	140	4	IPR000483
Domain	LRRCT	LINGO3 LRG1 LRIG3 ADGRA3	4.70e-03	90	140	4	SM00082
Domain	Dynein_HC_stalk	DNHD1 DYNC1H1	4.79e-03	14	140	2	IPR024743
Domain	Dynein_heavy_dom-2	DNHD1 DYNC1H1	4.79e-03	14	140	2	IPR013602
Domain	DHC_N2	DNHD1 DYNC1H1	4.79e-03	14	140	2	PF08393
Domain	MT	DNHD1 DYNC1H1	4.79e-03	14	140	2	PF12777
Domain	FN3_dom	NPHS1 SDK2 DSCAM SPEG IGDCC3 ASTN2	4.96e-03	209	140	6	IPR003961
Domain	WD_REPEATS_1	TEP1 SEC31B AAAS GTF3C2 TLE2 NBEAL2 TLE4	5.03e-03	278	140	7	PS00678
Domain	WD_REPEATS_2	TEP1 SEC31B AAAS GTF3C2 TLE2 NBEAL2 TLE4	5.13e-03	279	140	7	PS50082
Domain	WD_REPEATS_REGION	TEP1 SEC31B AAAS GTF3C2 TLE2 NBEAL2 TLE4	5.13e-03	279	140	7	PS50294
Domain	DHC_fam	DNHD1 DYNC1H1	5.49e-03	15	140	2	IPR026983
Domain	Dynein_heavy	DNHD1 DYNC1H1	5.49e-03	15	140	2	PF03028
Domain	Dynein_heavy_dom	DNHD1 DYNC1H1	5.49e-03	15	140	2	IPR004273
Domain	BAR_dom	ARHGEF38 SNX30	6.25e-03	16	140	2	IPR004148
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	SCN1A SCN2A SCN3A SCN9A	7.00e-05	31	102	4	M877
Pathway	REACTOME_PHASE_0_RAPID_DEPOLARISATION	SCN1A SCN2A SCN3A SCN9A	7.95e-05	32	102	4	M27455
Pubmed	A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.	SCN1A SCN2A SCN3A SCN9A	1.49e-09	5	146	4	8812438
Pubmed	A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.	SCN1A SCN2A SCN3A SCN9A	4.44e-09	6	146	4	23652591
Pubmed	International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.	SCN1A SCN2A SCN3A SCN9A	3.69e-08	9	146	4	16382098
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	EPPK1 MFHAS1 SPEG LAMB3 TEP1 KIFC2 SNX30 TMEM129 FASN CELSR1 CELSR3 CANT1 NBEAL2 NAV1 LRP4 TANC1 NUP188 AGRN PRRT4 DYNC1H1	4.27e-08	1105	146	20	35748872
Pubmed	Voltage-gated sodium channels in taste bud cells.	SCN2A SCN3A SCN9A	7.25e-08	3	146	3	19284629
Pubmed	Mutations in the sodium channel genes SCN1A, SCN3A, and SCN9A in children with epilepsy with febrile seizures plus(EFS+).	SCN1A SCN3A SCN9A	7.25e-08	3	146	3	33895391
Pubmed	SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.	SCN1A SCN2A SCN3A	7.25e-08	3	146	3	23859570
Pubmed	Sodium channels SCN1A, SCN2A and SCN3A in familial autism.	SCN1A SCN2A SCN3A	7.25e-08	3	146	3	12610651
Pubmed	Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.	SCN1A SCN2A SCN3A	7.25e-08	3	146	3	18784617
Pubmed	Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.	SCN1A SCN2A SCN3A	7.25e-08	3	146	3	17544618
Pubmed	Early expression of sodium channel transcripts and sodium current by cajal-retzius cells in the preplate of the embryonic mouse neocortex.	SCN1A SCN2A SCN3A	7.25e-08	3	146	3	14973256
Pubmed	Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.	SCN1A SCN2A SCN3A SCN9A	2.07e-07	13	146	4	15123669
Pubmed	Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.	SCN1A SCN2A SCN3A	2.89e-07	4	146	3	17537961
Pubmed	Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population.	SCN1A SCN2A SCN3A	2.89e-07	4	146	3	35801810
Pubmed	Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.	SCN1A SCN2A SCN3A	2.89e-07	4	146	3	35031483
Pubmed	Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.	SCN1A SCN2A SCN3A	2.89e-07	4	146	3	29578003
Pubmed	Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.	SCN1A SCN2A SCN3A	2.89e-07	4	146	3	8974318
Pubmed	Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2.	SCN1A SCN2A SCN3A	7.20e-07	5	146	3	1679748
Pubmed	Case-control association study of polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, SCN3A, SCN1B, and SCN2B and epilepsy.	SCN1A SCN2A SCN3A	7.20e-07	5	146	3	24337656
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	LAMB3 MINPP1 ITGA7 ADAM12 PAICS SIAE CELSR1 GLA CELSR3 CANT1 MICAL2 LRP4 TMEM231 TAP1 AGRN PBXIP1 ADGRA3 PPP6R3	3.16e-06	1201	146	18	35696571
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	PDE3B DENND4A LAMB3 FAM91A1 GIGYF1 ANKZF1 WASH6P TUBGCP3 GIGYF2 TANC1 NMT1 AGRN PBXIP1	3.95e-06	650	146	13	38777146
Pubmed	Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.	SCN1A SCN2A SCN3A	5.98e-06	9	146	3	15746173
Pubmed	International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.	ADGRB3 CELSR1 CELSR3 ADGRA3	1.11e-05	33	146	4	25713288
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	NES EPPK1 FAM91A1 FASN GIGYF2 TANC1 CNN2 DYNC1H1	1.36e-05	256	146	8	33397691
Pubmed	Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.	SCN1A SCN2A SCN3A	1.55e-05	12	146	3	30175250
Pubmed	Quantitative trait loci mapping of genes that influence the sensitivity and tolerance to ethanol-induced hypothermia in BXD recombinant inbred mice.	SCN1A SCN2A SCN3A	1.55e-05	12	146	3	8169823
Pubmed	Array-CGH detection of a de novo 2.8 Mb deletion in 2q24.2-->q24.3 in a girl with autistic features and developmental delay.	SCN2A SCN3A	1.75e-05	2	146	2	20346423
Pubmed	Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice.	SCN1A SCN2A	1.75e-05	2	146	2	10827969
Pubmed	Differential role of sodium channels SCN1A and SCN2A gene polymorphisms with epilepsy and multiple drug resistance in the north Indian population.	SCN1A SCN2A	1.75e-05	2	146	2	19694741
Pubmed	Genomic structures of SCN2A and SCN3A - candidate genes for deafness at the DFNA16 locus.	SCN2A SCN3A	1.75e-05	2	146	2	11245985
Pubmed	Comparative gene mapping of the human and mouse TEP1 genes, which encode one protein component of telomerases.	TEP1 TAP1	1.75e-05	2	146	2	9403057
Pubmed	Differential expression of two sodium channel subtypes in human brain.	SCN1A SCN2A	1.75e-05	2	146	2	1317301
Pubmed	Duplication of the sodium channel gene cluster on 2q24 in children with early onset epilepsy.	SCN2A SCN3A	1.75e-05	2	146	2	23016767
Pubmed	Whole gene duplication of SCN2A and SCN3A is associated with neonatal seizures and a normal intellectual development.	SCN2A SCN3A	1.75e-05	2	146	2	27153334
Pubmed	Characterization of a novel cation transporter ATPase gene (ATP13A4) interrupted by 3q25-q29 inversion in an individual with language delay.	ATP13A4 ATP13A5	1.75e-05	2	146	2	15925480
Pubmed	Electrophysiological Differences between the Same Pore Region Mutation in SCN1A and SCN3A.	SCN1A SCN3A	1.75e-05	2	146	2	24990319
Pubmed	Na+ current properties in islet α- and β-cells reflect cell-specific Scn3a and Scn9a expression.	SCN3A SCN9A	1.75e-05	2	146	2	25172946
Pubmed	Clinical exome sequencing identifies two novel mutations of the SCN1A and SCN2A genes in Moroccan patients with epilepsy: a case series.	SCN1A SCN2A	1.75e-05	2	146	2	31439038
Pubmed	Lrp4 is a retrograde signal for presynaptic differentiation at neuromuscular synapses.	LRP4 AGRN	1.75e-05	2	146	2	22854782
Pubmed	Severe epilepsy, retardation, and dysmorphic features with a 2q deletion including SCN1A and SCN2A.	SCN1A SCN2A	1.75e-05	2	146	2	15249644
Pubmed	Mapping of a FEB3 homologous febrile seizure locus on mouse chromosome 2 containing candidate genes Scn1a and Scn3a.	SCN1A SCN3A	1.75e-05	2	146	2	27690330
Pubmed	Validation of LRG1 as a potential biomarker for detection of epithelial ovarian cancer by a blinded study.	MUC16 LRG1	1.75e-05	2	146	2	25799488
Pubmed	Correlations in timing of sodium channel expression, epilepsy, and sudden death in Dravet syndrome.	SCN1A SCN3A	1.75e-05	2	146	2	23965409
Pubmed	SCN1A and SCN2A polymorphisms are associated with response to valproic acid in Chinese epilepsy patients.	SCN1A SCN2A	1.75e-05	2	146	2	30693367
Pubmed	Association between SCN1A and SCN2A mutations and clinical/EEG features in Chinese patients from epilepsy or severe seizures.	SCN1A SCN2A	1.75e-05	2	146	2	29649454
Pubmed	Genetic Method for Labeling Electrically Coupled Cells: Application to Retina.	SDK2 SLC15A2	1.75e-05	2	146	2	26778956
Pubmed	Effects of SCN1A and SCN2A polymorphisms on responsiveness to valproic acid monotherapy in epileptic children.	SCN1A SCN2A	1.75e-05	2	146	2	33096315
Pubmed	Missense mutations in sodium channel SCN1A and SCN2A predispose children to encephalopathy with severe febrile seizures.	SCN1A SCN2A	1.75e-05	2	146	2	26311622
Pubmed	The developmental changes of Na(v)1.1 and Na(v)1.2 expression in the human hippocampus and temporal lobe.	SCN1A SCN2A	1.75e-05	2	146	2	21377452
Pubmed	Confirmation of quantitative trait loci for alcohol preference in mice.	SCN1A SCN2A SCN3A	3.18e-05	15	146	3	9726281
Pubmed	Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders.	GIGYF1 TRIP12 SCN2A DYNC1H1	3.24e-05	43	146	4	36950384
Pubmed	Association of SCN1A, SCN2A, and UGT2B7 Polymorphisms with Responsiveness to Valproic Acid in the Treatment of Epilepsy.	SCN1A SCN2A	5.24e-05	3	146	2	32185219
Pubmed	Clinical exome sequencing as the first-tier test for diagnosing developmental disorders covering both CNV and SNV: a Chinese cohort.	SCN1A SCN2A	5.24e-05	3	146	2	32005694
Pubmed	MuSK myasthenia gravis IgG4 disrupts the interaction of LRP4 with MuSK but both IgG4 and IgG1-3 can disperse preformed agrin-independent AChR clusters.	LRP4 AGRN	5.24e-05	3	146	2	24244707
Pubmed	Fatty acid synthase downregulation contributes to acute lung injury in murine diet-induced obesity.	LEP FASN	5.24e-05	3	146	2	31287803
Pubmed	Agrin binds to the N-terminal region of Lrp4 protein and stimulates association between Lrp4 and the first immunoglobulin-like domain in muscle-specific kinase (MuSK).	LRP4 AGRN	5.24e-05	3	146	2	21969364
Pubmed	GAPDH-mediated posttranscriptional regulations of sodium channel Scn1a and Scn3a genes under seizure and ketogenic diet conditions.	SCN1A SCN3A	5.24e-05	3	146	2	27816501
Pubmed	The flamingo-related mouse Celsr family (Celsr1-3) genes exhibit distinct patterns of expression during embryonic development.	CELSR1 CELSR3	5.24e-05	3	146	2	11677057
Pubmed	Leptin receptor expressing neurons express phosphodiesterase-3B (PDE3B) and leptin induces STAT3 activation in PDE3B neurons in the mouse hypothalamus.	PDE3B LEP	5.24e-05	3	146	2	26297880
Pubmed	Nav1.2 is expressed in caudal ganglionic eminence-derived disinhibitory interneurons: Mutually exclusive distributions of Nav1.1 and Nav1.2.	SCN1A SCN2A	5.24e-05	3	146	2	28784306
Pubmed	Activation of G0/G1 switch gene 2 by endoplasmic reticulum stress enhances hepatic steatosis.	LEP ATF4	5.24e-05	3	146	2	31271806
Pubmed	Hepatic FASN deficiency differentially affects nonalcoholic fatty liver disease and diabetes in mouse obesity models.	LEP FASN	5.24e-05	3	146	2	37681411
Pubmed	Abnormal expression of voltage-gated sodium channels Nav1.7, Nav1.3 and Nav1.8 in trigeminal neuralgia.	SCN3A SCN9A	5.24e-05	3	146	2	19699781
Pubmed	The relationship among integrin alpha 7, CD133 and Nestin as well as their correlation with clinicopathological features and prognosis in astrocytoma patients.	NES ITGA7	5.24e-05	3	146	2	35430343
Pubmed	Variable patterns of mutation density among NaV1.1, NaV1.2 and NaV1.6 point to channel-specific functional differences associated with childhood epilepsy.	SCN1A SCN2A	5.24e-05	3	146	2	32845893
Pubmed	Comparison and optimization of in silico algorithms for predicting the pathogenicity of sodium channel variants in epilepsy.	SCN1A SCN2A	5.24e-05	3	146	2	28518218
Pubmed	Gene-to-gene interaction between sodium channel-related genes in determining the risk of antiepileptic drug resistance.	SCN1A SCN2A	5.24e-05	3	146	2	19270815
Pubmed	Identification of functional voltage-gated Na(+) channels in cultured human pulmonary artery smooth muscle cells.	SCN2A SCN3A	5.24e-05	3	146	2	16052353
Pubmed	Association of SCN1A, SCN2A and ABCC2 gene polymorphisms with the response to antiepileptic drugs in Chinese Han patients with epilepsy.	SCN1A SCN2A	5.24e-05	3	146	2	25155934
Pubmed	Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy.	SCN1A SCN2A	5.24e-05	3	146	2	17928448
Pubmed	The role of CA-125, GLS and FASN in predicting cytoreduction for epithelial ovarian cancers.	MUC16 FASN	5.24e-05	3	146	2	32698888
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SPEG FAM91A1 ALS2 LRIG3 TLE4 BRINP2 NAV1 GIGYF2 DYNC1H1	5.94e-05	407	146	9	12693553
Pubmed	Molecular genetics of successful smoking cessation: convergent genome-wide association study results.	DSCAM ARHGEF38 TACC2 ADAM12 MYO18B	6.97e-05	101	146	5	18519826
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	EPPK1 IRAK2 TMEM129 FASN ARHGEF10 SLC49A4 NAV1 DYNC1H1	8.53e-05	332	146	8	37433992
Pubmed	The Xbp1s/GalE axis links ER stress to postprandial hepatic metabolism.	GALE LEP	1.04e-04	4	146	2	23257357
Pubmed	Targeted DNA Sequencing from Autism Spectrum Disorder Brains Implicates Multiple Genetic Mechanisms.	SCN1A SCN2A	1.04e-04	4	146	2	26637798
Pubmed	TLE expression correlates with mouse embryonic segmentation, neurogenesis, and epithelial determination.	TLE2 TLE4	1.04e-04	4	146	2	8645603
Pubmed	4EHP and GIGYF1/2 Mediate Translation-Coupled Messenger RNA Decay.	GIGYF1 GIGYF2	1.04e-04	4	146	2	33053355
Pubmed	Hereditary Sensory and Autonomic Neuropathy Type II	SCN9A RETREG1	1.04e-04	4	146	2	21089229
Pubmed	Multimerin-2 is a ligand for group 14 family C-type lectins CLEC14A, CD93 and CD248 spanning the endothelial pericyte interface.	CD248 CLEC14A	1.04e-04	4	146	2	28671670
Pubmed	Dorsal root ganglia isolated from Nf1+/- mice exhibit increased levels of mRNA expression of voltage-dependent sodium channels.	SCN1A SCN9A	1.04e-04	4	146	2	22260870
Pubmed	PARP1-stabilised FOXQ1 promotes ovarian cancer progression by activating the LAMB3/WNT/β-catenin signalling pathway.	FOXQ1 LAMB3	1.04e-04	4	146	2	38297082
Pubmed	Panel of markers can accurately predict endometriosis in a subset of patients.	MUC16 LEP	1.04e-04	4	146	2	17706208
Pubmed	The adhesion GPCRs CELSR1-3 and LPHN3 engage G proteins via distinct activation mechanisms.	CELSR1 CELSR3	1.04e-04	4	146	2	37224017
Pubmed	Nestin negatively regulates postsynaptic differentiation of the neuromuscular synapse.	NES AGRN	1.04e-04	4	146	2	21278733
Pubmed	Novel markers in the diagnostics of endometriomas: Urocortin, ghrelin, and leptin or leukocytes, fibrinogen, and CA-125?	MUC16 LEP	1.04e-04	4	146	2	25951715
Pubmed	Nav1.7 as a chondrocyte regulator and therapeutic target for osteoarthritis.	SCN9A NAV1	1.04e-04	4	146	2	38172636
Pubmed	Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus.	SCN1A SCN2A	1.04e-04	4	146	2	21156207
Pubmed	The collagen ColQ binds to LRP4 and regulates the activation of the Muscle-Specific Kinase-LRP4 receptor complex by agrin at the neuromuscular junction.	LRP4 AGRN	1.04e-04	4	146	2	37356721
Pubmed	Sustained ER stress promotes hyperglycemia by increasing glucagon action through the deubiquitinating enzyme USP14.	LEP ATF4	1.04e-04	4	146	2	31594848
Pubmed	Expression of phosphacan and neurocan during early development of mouse retinofugal pathway.	NES NCAN	1.04e-04	4	146	2	15283989
Pubmed	Loss of MAGEL2 in Prader-Willi syndrome leads to decreased secretory granule and neuropeptide production.	MAGEL2 WASH6P	1.04e-04	4	146	2	32879135
Pubmed	The steady-state level of CDK4 protein is regulated by antagonistic actions between PAQR4 and SKP2 and involved in tumorigenesis.	PAQR4 FBXO4	1.04e-04	4	146	2	28992327
Pubmed	Developmental expression profiles of Celsr (Flamingo) genes in the mouse.	CELSR1 CELSR3	1.04e-04	4	146	2	11850187
Pubmed	Slowed conduction and thin myelination of peripheral nerves associated with mutant rho Guanine-nucleotide exchange factor 10.	CLN8 ARHGEF10	1.04e-04	4	146	2	14508709
Pubmed	Hepatocyte-secreted DPP4 in obesity promotes adipose inflammation and insulin resistance.	LEP ATF4	1.04e-04	4	146	2	29562231
Pubmed	Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins.	TLE2 TLE4	1.74e-04	5	146	2	1303260
Pubmed	Early development of electrical excitability in the mouse enteric nervous system.	SCN3A SCN9A	1.74e-04	5	146	2	22875929
Pubmed	Expression of Epiplakin1 in the developing and adult mouse retina.	NES EPPK1	1.74e-04	5	146	2	20151282
Pubmed	PAQR4 regulates adipocyte function and systemic metabolic health by mediating ceramide levels.	PAQR4 LEP	1.74e-04	5	146	2	38961186
Cytoband	Ensembl 112 genes in cytogenetic band chr2q24	SCN1A SCN2A SCN3A SCN9A TANC1	5.84e-05	127	147	5	chr2q24
Cytoband	19p13.3	IZUMO4 APBA3 LINGO3 LRG1 TLE2 CNN2	1.22e-04	237	147	6	19p13.3
Cytoband	Ensembl 112 genes in cytogenetic band chr19p13	IZUMO4 TMEM221 MUC16 APBA3 LINGO3 FCHO1 LRG1 TLE2 NCAN CNN2	2.64e-04	797	147	10	chr19p13
Cytoband	2q24	SCN3A SCN9A	5.50e-04	11	147	2	2q24
Cytoband	2q12	SLC5A7 IL1R2	6.58e-04	12	147	2	2q12
Cytoband	8p23	CLN8 ARHGEF10	9.04e-04	14	147	2	8p23
Cytoband	11p15.1	PDE3B MRGPRX3 OTOG	9.63e-04	60	147	3	11p15.1
Cytoband	2q24.3	SCN1A SCN2A	1.19e-03	16	147	2	2q24.3
GeneFamily	Sodium voltage-gated channel alpha subunits	SCN1A SCN2A SCN3A SCN9A	1.00e-07	9	98	4	1203
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	SDK2 DSCAM SPEG IGDCC3 LINGO3 LRIG3 ADGRA3	2.73e-05	161	98	7	593
GeneFamily	Adhesion G protein-coupled receptors, subfamily C\|CELSR cadherins	CELSR1 CELSR3	8.69e-05	3	98	2	913
GeneFamily	Adhesion G protein-coupled receptors, subfamily C\|CELSR cadherins	CELSR1 CELSR3	8.69e-05	3	98	2	1189
GeneFamily	Parkinson disease associated genes\|ATPase orphan transporters	ATP13A4 ATP13A5	2.88e-04	5	98	2	1213
GeneFamily	WD repeat domain containing	TEP1 SEC31B AAAS GTF3C2 TLE2 NBEAL2 TLE4	5.58e-04	262	98	7	362
GeneFamily	Fibronectin type III domain containing	NPHS1 SDK2 DSCAM IGDCC3 ASTN2	1.79e-03	160	98	5	555
Coexpression	GSE17721_PAM3CSK4_VS_CPG_24H_BMDC_DN	NPHS1 RBM42 SYS1 TRIP12 CLEC14A VWA5A NMT1 AGRN DYNC1H1	2.03e-06	200	147	9	M3875
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ATP13A4 ARHGEF38 TACC2 SNX30 SIAE FASN SCN1A FAM149A	2.55e-07	192	147	8	cc9911e182a289779a2612bc213daae5607689e7
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGEF38 DGKD TACC2 SNX30 SIAE FASN MICAL2 SCN1A	3.23e-07	198	147	8	2e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCell	10x5'v1-week_17-19-Hematopoietic-HSC/MPP_and_pro-ELP\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	SDK2 TMEM221 CD248 CLEC14A TLE4 SCN3A MN1	1.59e-06	170	147	7	a50e558d0b38100ccbdccb90647fe93e85bffd86
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-Proximal_secretory_3\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ATP13A4 MUC16 KIFC2 FER1L6 CELSR1 C1orf226 SLC15A2	2.00e-06	176	147	7	8d9d0fb46c418b2067be58aec822e8c2b1561461
ToppCell	Adult-Epithelial-club_cell-D175\|Adult / Lineage, Cell type, age group and donor	FOXQ1 ARHGEF38 PAICS SOCS7 LRIG3 CELSR1 ADGRA3	2.07e-06	177	147	7	d652b7d84fe6aa38319d8d5adc72c70441bd0088
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ATP13A4 LAMB3 TACC2 RIPK4 KIFC2 CELSR1 SLC15A2	2.23e-06	179	147	7	04ce3673e46606f63d9c87bcba3a64c96817d812
ToppCell	PCW_13-14-Neuronal-Neuronal_postreplicative-neuro_neuronal_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DSCAM SLC5A7 CELSR3 SCN1A SCN2A SCN3A HRH3	2.23e-06	179	147	7	af0b54c9ea0b6e4210f22dbb6e88ecd3276a5f86
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ATP13A4 LAMB3 RIPK4 KIFC2 CELSR1 SLC15A2 AGRN	2.41e-06	181	147	7	b45b11428d13950369347e051d4d517efb2bd4fd
ToppCell	COPD-Epithelial-Basal\|COPD / Disease state, Lineage and Cell class	ATP13A4 LAMB3 RIPK4 LRIG3 CELSR1 TANC1 ADGRA3	2.59e-06	183	147	7	0f760e393edc91009bf6c7e02eeac039a1dfb4ed
ToppCell	wk_20-22-Mesenchymal-Myofibro_&_SMC-Myofibro_3\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	NES CD248 ADGRB3 MINPP1 TLE2 LRP4 TANC1	2.59e-06	183	147	7	f4ea7113ce9099222743d9ff02388d3d8a9e987b
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D175\|Adult / Lineage, Cell type, age group and donor	ATP13A4 EPPK1 ARHGEF38 LRIG3 SIAE SCN1A SCN9A	3.09e-06	188	147	7	ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ATP13A4 ARHGEF38 LAMB3 RIPK4 CELSR1 SCN9A FAM149A	3.20e-06	189	147	7	7659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	TMEM221 IGDCC3 ITGA7 FBXO4 OTOG	3.30e-06	69	147	5	1592edde44c3927d6a2350eb00f92c10d3adf692
ToppCell	COVID-19-lung-AT2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ATP13A4 ARHGEF38 TACC2 SNX30 FASN MICAL2 SCN1A	3.32e-06	190	147	7	27a1a86620fe9b5ee930d388b32352206485e6d0
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	ATP13A4 ARHGEF38 TACC2 SNX30 FASN MICAL2 SCN1A	3.43e-06	191	147	7	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	Epithelial-alveolar_epithelial_cell_type_2\|World / Lineage, Cell type, age group and donor	ATP13A4 ARHGEF38 TACC2 SNX30 FASN MICAL2 SCN1A	3.55e-06	192	147	7	58c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ATP13A4 ARHGEF38 LAMB3 RIPK4 CELSR1 SCN9A FAM149A	3.55e-06	192	147	7	b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCell	NS-critical-d_07-13-Epithelial-Secretory\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	GALE FOXQ1 ATP13A5 FER1L6 LRIG3 SLC15A2 TLE2	3.80e-06	194	147	7	2172d951896265243d14996eacce5aab5e14e26e
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ATP13A4 ARHGEF38 LAMB3 RIPK4 CELSR1 SCN9A FAM149A	3.80e-06	194	147	7	f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCell	Bronchial-10x5prime-Epithelial-Epi_alveolar-Dividing_AT2\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ATP13A4 LAMB3 TACC2 CELSR3 MICAL2 SCN1A BRINP2	4.21e-06	197	147	7	49689a03ab31e53386dbe15c77c09ca3a14ebf4e
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ATP13A4 ARHGEF38 TACC2 SNX30 SIAE MICAL2 SCN1A	4.35e-06	198	147	7	f948391296c261c473d339069a6d0f20ccd6f38f
ToppCell	Bronchial-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ATP13A4 ARHGEF38 TACC2 SNX30 CELSR1 MICAL2 SCN1A	4.50e-06	199	147	7	5f7da3eab58ace6cddb3179a415cd839d5767958
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ATP13A4 ARHGEF38 DGKD TACC2 SNX30 MICAL2 SCN1A	4.50e-06	199	147	7	8587bd98de7767a575088afbea07a1feb4516b9b
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DSCAM TACC2 SCN1A SCN2A SCN9A NAV1 LRP4	4.50e-06	199	147	7	19a97e27a4758e794ce7246d295e112b47931a48
ToppCell	Tracheal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GALE ARHGEF38 MUC16 TACC2 LRIG3 CELSR1 TANC1	4.65e-06	200	147	7	d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	NES PDE3B ARHGEF10 TLE4 SCN9A TANC1 DYNC1H1	4.65e-06	200	147	7	79e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Alv_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	NES PDE3B ARHGEF10 TLE4 SCN9A RETREG1 TANC1	4.65e-06	200	147	7	b7533c571eeea0cb3678e1a57d3dc036fa8d0f49
ToppCell	Parenchymal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_epineurial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	IZUMO4 FAM91A1 ITGA7 LEP MFSD14A FBXO4 MICAL2	4.65e-06	200	147	7	be46efc899d06c55ee297bee3126f69bcdb2048b
ToppCell	PND07-28-samps-Mesenchymal-Mesothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	TMEM221 MUC16 RIPK4 PKHD1L1 SBSN C1orf226	1.33e-05	156	147	6	574f761962a7dd3308bd41fc529dd3ea1b8625f8
ToppCell	PND07-28-samps-Mesenchymal-Mesothelial-Mesothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	TMEM221 MUC16 RIPK4 PKHD1L1 SBSN C1orf226	1.33e-05	156	147	6	605d95a900e1443d3f6aae163ef2e893d3293203
ToppCell	metastatic_Brain-T/NK_cells-Cytotoxic_CD8+_T\|T/NK_cells / Location, Cell class and cell subclass	NES ADGRB3 MUC16 CELSR1 SLC15A2 TMEM231	1.59e-05	161	147	6	e6e294b4ba911c1327664f1a0f93207096c6de03
ToppCell	10x5'v1-week_17-19-Hematopoietic-HSC/MPP_and_pro\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	SDK2 TMEM221 CLEC14A TLE4 SCN3A MN1	1.71e-05	163	147	6	edca1d1a345109dbdeb7ee5464faefab1993fdb2
ToppCell	356C-Myeloid-Dendritic-cDC_activated\|356C / Donor, Lineage, Cell class and subclass (all cells)	IZUMO4 ADAM12 LEP NAV1 MYO18B CHST7	1.96e-05	167	147	6	43a9375fdbafd7450c553e4620e21537e08639dd
ToppCell	droplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPHS1 NES CD248 SPEG ADAM12 ASTN2	2.10e-05	169	147	6	87116c33c5ca8cb1862e103e5607b1df4d264569
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXQ1 DSCAM ATP13A5 PKHD1L1 SCN3A SCN9A	2.10e-05	169	147	6	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	AT1-AT2_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	SLC5A7 LAMB3 SLC15A2 SCN3A AGRN PBXIP1	2.32e-05	172	147	6	0be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPHS1 NES LAMB3 CELSR1 RETREG1 LRP4	2.39e-05	173	147	6	c62e3ffed55bbb00dcaef6da0aab8446f3f55085
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPHS1 NES LAMB3 CELSR1 RETREG1 LRP4	2.39e-05	173	147	6	f612d4ea9ab8dcde475f4118bca3e49be786e7fa
ToppCell	Control-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ATP13A4 LAMB3 KIFC2 CELSR1 SLC15A2 NBEAL2	2.72e-05	177	147	6	9af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCell	Epithelial-basal_cell\|World / Lineage, Cell type, age group and donor	ATP13A4 SLC5A7 LAMB3 RIPK4 LRIG3 CELSR1	2.90e-05	179	147	6	d9be6647ec7b22747dc00dce4ea307b6af412dfa
ToppCell	Control-Epithelial_cells-AT2\|Control / group, cell type (main and fine annotations)	ARHGEF38 TACC2 SNX30 FASN MICAL2 SCN1A	2.99e-05	180	147	6	198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell	COPD-Epithelial-Basal\|World / Disease state, Lineage and Cell class	ATP13A4 LAMB3 RIPK4 CELSR1 TANC1 ADGRA3	3.08e-05	181	147	6	6d8a886b4afe729f8a05b9c0f4ea9375de735da4
ToppCell	Control-Epithelial_cells-Airway_club\|Control / group, cell type (main and fine annotations)	ATP13A4 MFHAS1 ARHGEF38 TACC2 SNX30 FAM149A	3.08e-05	181	147	6	c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PAQR4 SOCS7 FER1L6 CELSR1 SLC15A2 FAM149A	3.18e-05	182	147	6	215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCell	3'_v3-Lung-Myeloid_Dendritic-DC1\|Lung / Manually curated celltypes from each tissue	IRAK2 CLEC14A SCN9A TAP1 CNN2 FAM149A	3.28e-05	183	147	6	e4cbd39575b5a4612d9934532e3bad63286f8aa5
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXQ1 TMEM221 LRG1 SOCS7 CELSR1 ADGRA3	3.28e-05	183	147	6	b0b5a41f1a40f9c946d0dc8b67eaccdd9f9b73a5
ToppCell	facs-Trachea-18m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPPK1 FOXQ1 LAMB3 RIPK4 CELSR1 SLC15A2	3.38e-05	184	147	6	45ff845ceed5960a997545c1009012b65e377d50
ToppCell	COVID-19-Epithelial_cells-AT2\|COVID-19 / group, cell type (main and fine annotations)	ATP13A4 ARHGEF38 TACC2 FASN MICAL2 SCN1A	3.38e-05	184	147	6	369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell	facs-Trachea-18m-Epithelial-airway_epithelial-respiratory_basal_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPPK1 FOXQ1 LAMB3 RIPK4 CELSR1 SLC15A2	3.38e-05	184	147	6	2cc2646dee3c6001f7c10b7449c17d1935021958
ToppCell	droplet-Heart-4Chambers-21m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND4A TCIRG1 ADAM12 PKHD1L1 LRG1 SCN3A	3.48e-05	185	147	6	bb5a4cf93534b9bcd0923f314c389d571e91e7f8
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPPK1 FOXQ1 LAMB3 RIPK4 CELSR1 SLC15A2	3.59e-05	186	147	6	37b93ebd64ebbd08193a746e5bc9b350c2570733
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ATP13A4 SDK2 LAMB3 TACC2 RIPK4 CELSR1	3.59e-05	186	147	6	4e94158db52df41d71e67b02b9895a358eebee0f
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ATP13A4 LAMB3 RIPK4 KIFC2 CELSR1 SLC15A2	3.59e-05	186	147	6	3aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD4-Tregs\|bone_marrow / Manually curated celltypes from each tissue	ADAM12 RETREG1 PPP1R3F CHST7 PBXIP1 CNN2	3.70e-05	187	147	6	bda716a64262325e6e68b281caf131f1840fd298
ToppCell	AT1_cells-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	LAMB3 DGKD MICAL2 NBEAL2 BRINP2 AGRN	3.70e-05	187	147	6	f1dda349335e08dbfc8395d373924037f5ad2fd6
ToppCell	facs-Trachea-nan-3m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPPK1 FOXQ1 LAMB3 RIPK4 CELSR1 SLC15A2	3.70e-05	187	147	6	fe9fc21192ede2eea61f419d20ccda254569d0a6
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPPK1 FOXQ1 LAMB3 RIPK4 CELSR1 SLC15A2	3.81e-05	188	147	6	8ffb5394f7b00ea483a5fe4df894d22fda935e5c
ToppCell	COVID-19-Epithelial_cells\|COVID-19 / group, cell type (main and fine annotations)	ATP13A4 ARHGEF38 TACC2 FASN CELSR1 MICAL2	3.81e-05	188	147	6	c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ATP13A4 LAMB3 SLC13A2 SNX30 CELSR1 MICAL2	3.81e-05	188	147	6	4bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPPK1 FOXQ1 LAMB3 RIPK4 CELSR1 SLC15A2	3.81e-05	188	147	6	137ed9958044fab7a13648affb469585d1c48cf6
ToppCell	facs-Trachea-3m-Epithelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPPK1 FOXQ1 LAMB3 RIPK4 CELSR1 SLC15A2	3.93e-05	189	147	6	f8959cc2c14899c8dfeb1b5e51e187537df2f03e
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D231\|Adult / Lineage, Cell type, age group and donor	ARHGEF38 DGKD TACC2 SNX30 MICAL2 SCN1A	3.93e-05	189	147	6	dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NES SDK2 CLEC14A PROB1 EXOC3L2 MN1	3.93e-05	189	147	6	e60a3d6aa84788c29f23439f1c747431ea581bc3
ToppCell	COVID-19-lung-Secretory\|lung / Disease (COVID-19 only), tissue and cell type	ATP13A4 ARHGEF38 LAMB3 FER1L6 LRIG3 CELSR1	3.93e-05	189	147	6	84d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCell	IPF-Epithelial-Basal\|IPF / Disease state, Lineage and Cell class	SDK2 LAMB3 TACC2 RIPK4 LRIG3 TANC1	4.04e-05	190	147	6	ea19e9ce954f2dfde97388db9695325cd92ab88f
ToppCell	droplet-Trachea-3m-Epithelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPPK1 FOXQ1 LAMB3 RIPK4 CELSR1 SLC15A2	4.04e-05	190	147	6	0114cf48612d78c3ada4d8a05850501fef6892c5
ToppCell	droplet-Trachea-3m-Epithelial-airway_epithelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPPK1 FOXQ1 LAMB3 RIPK4 CELSR1 SLC15A2	4.04e-05	190	147	6	01e7747547ea1f3049a11a1717565ba71dd52bdc
ToppCell	droplet-Trachea-nan-3m-Epithelial\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPPK1 FOXQ1 LAMB3 RIPK4 CELSR1 SLC15A2	4.04e-05	190	147	6	e647f9a2dcf7f2dffef53c45bbe171416518fd59
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3B ARHGEF10 CLEC14A TLE4 SCN9A TANC1	4.04e-05	190	147	6	474cbbab8f3b0a6881fa6c92edb78e43999f9ab0
ToppCell	droplet-Trachea-nan-3m-Epithelial-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPPK1 FOXQ1 LAMB3 RIPK4 CELSR1 SLC15A2	4.04e-05	190	147	6	434de72dde09644efbddcaa643a4a3eaf5f643bf
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ATP13A4 ARHGEF38 LAMB3 CELSR1 SCN9A FAM149A	4.16e-05	191	147	6	60ff989fe99d243a3d52955223680cdd1f1917a4
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ATP13A4 ARHGEF38 TACC2 SNX30 FASN SCN1A	4.16e-05	191	147	6	a0332a4ef629510fb313ec119195c44a3f704a80
ToppCell	(1)_Osterolineage_cells-(10)_OLC-1\|(1)_Osterolineage_cells / Cell class and subclass of bone marrow stroma cells in homeostatis	ADAM12 TSPAN17 TLE2 LRP4 TANC1 CNN2	4.16e-05	191	147	6	78ad7c555409ce1391bce406bc0f3ef575329ece
ToppCell	T_cells-Central_memory_CD4+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	PDE3B FCHO1 TLE2 RETREG1 PBXIP1 CNN2	4.16e-05	191	147	6	25dd538d6a361bd3367c8a1c0dfc9e7003061af3
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3B ARHGEF10 CLEC14A TLE4 SCN9A TANC1	4.29e-05	192	147	6	c618ede75dce3988c87a5b8f98d8e94e1dd66efd
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D122\|Adult / Lineage, Cell type, age group and donor	ARHGEF38 TACC2 SNX30 SIAE FASN SCN1A	4.29e-05	192	147	6	06013a07e3a873b1d1c0451643c528593ac32a9c
ToppCell	Adult-Epithelial\|Adult / Lineage, Cell type, age group and donor	ATP13A4 ARHGEF38 TACC2 CELSR1 MICAL2 TANC1	4.29e-05	192	147	6	efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCell	COVID-19-lung-Secretory\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ATP13A4 ARHGEF38 LAMB3 LRIG3 CELSR1 SLC15A2	4.29e-05	192	147	6	59261098ccb52306f837f632ebaea45b90ad30fe
ToppCell	IPF-Epithelial-Basal\|World / Disease state, Lineage and Cell class	SDK2 LAMB3 RIPK4 LRIG3 CELSR1 TANC1	4.29e-05	192	147	6	9b91e0b162e6f3ce86dd15cc33c2e745d069581f
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ARHGEF38 TACC2 SNX30 FASN MICAL2 SCN1A	4.41e-05	193	147	6	fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2\|Adult / Lineage, Cell type, age group and donor	ARHGEF38 TACC2 SNX30 FASN MICAL2 SCN1A	4.41e-05	193	147	6	738f4f0a9ddde2432b429ab46838e353b1790589
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3B ARHGEF10 CLEC14A TLE4 SCN9A TANC1	4.41e-05	193	147	6	a3636c35ed25aabe2f1aba016c9fe125327bbfaf
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ARHGEF38 TACC2 SNX30 FASN MICAL2 SCN1A	4.41e-05	193	147	6	f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCell	facs-Trachea-24m-Epithelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPPK1 FOXQ1 LAMB3 RIPK4 CELSR1 SLC15A2	4.41e-05	193	147	6	ec49a83b24371579d4ad46aad91c25115aa226f9
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DGKD TLE2 SCN9A ASTN2 TANC1 PRRT4	4.41e-05	193	147	6	5581a5ebcd21a2a8062ccfb917f088ec67a10a9c
ToppCell	facs-Lung-3m-Epithelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPPK1 ARHGEF38 LAMB3 FASN CELSR1 SLC15A2	4.41e-05	193	147	6	db5e43e0b571737e7006365bdf0575340b8b900b
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ARHGEF38 DGKD TACC2 SNX30 FASN MICAL2	4.54e-05	194	147	6	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DSCAM ARHGEF38 LAMB3 CELSR1 SCN3A SCN9A	4.54e-05	194	147	6	b30379f8dc41c86c746af9930541fbb4819d8fa0
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical\|TCGA-Thryoid / Sample_Type by Project: Shred V9	GALE FOXQ1 LAMB3 LRG1 LRP4 AGRN	4.54e-05	194	147	6	b46c54802b8d1e0a0a17f9ed8e82eaf5e7f4849d
ToppCell	facs-Tongue\|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPPK1 LAMB3 RIPK4 KCNK7 SBSN CELSR1	4.67e-05	195	147	6	77128895db9221a64a171082d468ebcd6380c936
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ARHGEF38 DGKD TACC2 SNX30 FASN SCN1A	4.81e-05	196	147	6	7e5addaa844e66f8160e05858c341866a80aed23
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SLC5A7 CELSR3 SCN2A NCAN SCN3A BRINP2	4.81e-05	196	147	6	4bdc304c0c9d8bebe1a6a8a27e44acd1e8113725
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	LAMB3 SLC13A2 LRG1 FASN CELSR1 SCN1A	4.95e-05	197	147	6	1485933986921ff45669d9b7501c8d17050b3e97
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_naive-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TCIRG1 LRG1 LEP IL1R2 CNN2 SECTM1	4.95e-05	197	147	6	d2b2eaa6f7294ff56b84a69c8727c7e0f9fd0466
ToppCell	LPS_only-Epithelial_alveolar-AT_2\|LPS_only / Treatment groups by lineage, cell group, cell type	GALE IZUMO4 LAMB3 SLC13A2 LRG1 FASN	5.09e-05	198	147	6	d087e738d69ca9853553fde46d4e7a8906439d32
ToppCell	distal-Epithelial-Alveolar_Epithelial_Type_2-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ARHGEF38 LAMB3 LRG1 SNX30 FASN MICAL2	5.09e-05	198	147	6	de5748c2b66ecc432974cf095ecd241369579f7c
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ATP13A4 ARHGEF38 TACC2 SNX30 MICAL2 SCN1A	5.23e-05	199	147	6	725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCell	medial-2-Epithelial-Alveolar_Epithelial_Type_1\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ATP13A4 LAMB3 TACC2 SLC15A2 MICAL2 AGRN	5.23e-05	199	147	6	456460c761e26ed4b1d88d9bee4d2a7c9bd9d416
ToppCell	Parenchymal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ATP13A4 ARHGEF38 TACC2 SNX30 CELSR1 MICAL2	5.23e-05	199	147	6	5cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCell	medial-Epithelial-Alveolar_Epithelial_Type_1-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ATP13A4 LAMB3 TACC2 SLC15A2 MICAL2 AGRN	5.23e-05	199	147	6	5263338242f95c04690d0795749ccc20b0d19f7a
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN1A SCN2A SCN3A SCN9A	9.97e-08	10	140	4	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN1A SCN2A SCN3A SCN9A	9.97e-08	10	140	4	DOID:0080422 (implicated_via_orthology)
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN1A SCN2A SCN3A SCN9A	2.33e-07	12	140	4	DOID:0060170 (implicated_via_orthology)
Disease	anxiety disorder (implicated_via_orthology)	SCN1A SCN2A SCN3A SCN9A	3.32e-06	22	140	4	DOID:2030 (implicated_via_orthology)
Disease	Generalized Epilepsy with Febrile Seizures Plus	SCN1A SCN2A SCN9A	8.60e-06	9	140	3	C3502809
Disease	epilepsy (implicated_via_orthology)	ITGA7 SLC13A2 SCN1A SCN2A SCN3A SCN9A DYNC1H1	1.34e-05	163	140	7	DOID:1826 (implicated_via_orthology)
Disease	Early Infantile Epileptic Encephalopathy 6	SCN1A SCN9A	2.24e-05	2	140	2	C4551549
Disease	Infantile Severe Myoclonic Epilepsy	SCN1A SCN2A SCN9A	2.89e-05	13	140	3	C0751122
Disease	Myasthenic Syndromes, Congenital, Slow Channel	SLC5A7 LRP4 AGRN	5.60e-05	16	140	3	C0751885
Disease	Congenital Myasthenic Syndromes, Postsynaptic	SLC5A7 LRP4 AGRN	6.77e-05	17	140	3	C0751883
Disease	Neurodevelopmental Disorders	DSCAM TRIP12 SCN1A SCN2A GIGYF2	8.32e-05	93	140	5	C1535926
Disease	Congenital Myasthenic Syndromes, Presynaptic	SLC5A7 LRP4 AGRN	9.58e-05	19	140	3	C0751884
Disease	Neuropathy, Hereditary Sensory And Autonomic, Type IIA	SCN9A RETREG1	1.33e-04	4	140	2	C2752089
Disease	Hereditary sensory and autonomic neuropathy type 2	SCN9A RETREG1	1.33e-04	4	140	2	cv:C5574675
Disease	juvenile-onset Parkinson's disease (implicated_via_orthology)	ATP13A4 ATP13A5	1.33e-04	4	140	2	DOID:0060893 (implicated_via_orthology)
Disease	Neuropathy, hereditary sensory and autonomic, type 2A	SCN9A RETREG1	1.33e-04	4	140	2	cv:C2752089
Disease	Kufor-Rakeb syndrome (implicated_via_orthology)	ATP13A4 ATP13A5	1.33e-04	4	140	2	DOID:0060556 (implicated_via_orthology)
Disease	NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE IIA	SCN9A RETREG1	1.33e-04	4	140	2	201300
Disease	Myasthenic Syndromes, Congenital	SLC5A7 LRP4 AGRN	1.97e-04	24	140	3	C0751882
Disease	Hereditary Sensory Autonomic Neuropathy, Type 2	SCN9A RETREG1	2.21e-04	5	140	2	C0020072
Disease	Cerebral Small Vessel Diseases	GLA SCN1A	2.21e-04	5	140	2	C2733158
Disease	muscular disease (implicated_via_orthology)	FASN NMT1	2.21e-04	5	140	2	DOID:0080000 (implicated_via_orthology)
Disease	Sensory Neuropathy, Hereditary	SCN9A RETREG1	3.31e-04	6	140	2	C0699739
Disease	amyotrophic lateral sclerosis (implicated_via_orthology)	ATP13A4 ATP13A5 ALS2	3.86e-04	30	140	3	DOID:332 (implicated_via_orthology)
Disease	Seizure, Febrile, Simple	SCN1A SCN2A	4.62e-04	7	140	2	C0149886
Disease	Seizure, Febrile, Complex	SCN1A SCN2A	4.62e-04	7	140	2	C0751057
Disease	Hereditary Sensory Autonomic Neuropathy, Type 5	SCN9A RETREG1	4.62e-04	7	140	2	C0020075
Disease	Early Childhood Epilepsy, Myoclonic	SCN1A SCN9A	6.14e-04	8	140	2	C0393695
Disease	Idiopathic Myoclonic Epilepsy	SCN1A SCN9A	6.14e-04	8	140	2	C0338478
Disease	Symptomatic Myoclonic Epilepsy	SCN1A SCN9A	6.14e-04	8	140	2	C0338479
Disease	Benign Infantile Myoclonic Epilepsy	SCN1A SCN9A	6.14e-04	8	140	2	C0751120
Disease	granule cell layer dentate gyrus volume	EEF1AKMT2 ASTN2	6.14e-04	8	140	2	EFO_0009403
Disease	Myoclonic Encephalopathy	SCN1A SCN9A	6.14e-04	8	140	2	C0438414
Disease	Myoclonic Absence Epilepsy	SCN1A SCN9A	6.14e-04	8	140	2	C0393703
Disease	resting heart rate	EPPK1 SPEG MICAL2 TANC1 MN1	7.41e-04	149	140	5	EFO_0004351
Disease	Febrile Convulsions	SCN1A SCN2A	7.87e-04	9	140	2	C0009952
Disease	Myoclonic Epilepsy	SCN1A SCN9A	7.87e-04	9	140	2	C0014550
Disease	Epilepsy, Myoclonic, Infantile	SCN1A SCN9A	9.81e-04	10	140	2	C0917800
Disease	Proteinuria	NPHS1 MUC16 LEP	1.12e-03	43	140	3	C0033687
Disease	nucleus accumbens volume change measurement	DSCAM MUC16	1.20e-03	11	140	2	EFO_0021493
Disease	Myoclonic Astatic Epilepsy	SCN1A SCN9A	1.20e-03	11	140	2	C0393702
Disease	developmental disorder of mental health (implicated_via_orthology)	GIGYF1 GIGYF2 TANC1	1.64e-03	49	140	3	DOID:0060037 (implicated_via_orthology)
Disease	Hereditary Motor and Sensory-Neuropathy Type II	SCN9A RETREG1	1.68e-03	13	140	2	C0270914
Disease	neuronal ceroid lipofuscinosis (implicated_via_orthology)	ATP13A4 ATP13A5	1.96e-03	14	140	2	DOID:14503 (implicated_via_orthology)
Disease	MMR-related febrile seizures	SCN1A SCN2A	2.25e-03	15	140	2	EFO_0006519
Disease	Polyposis, Adenomatous Intestinal	LRG1 MUTYH	2.57e-03	16	140	2	C2713442
Disease	Familial Intestinal Polyposis	LRG1 MUTYH	2.57e-03	16	140	2	C2713443
Disease	Early infantile epileptic encephalopathy with suppression bursts	SCN1A SCN2A	2.57e-03	16	140	2	C0393706
Disease	Adenomatous Polyposis Coli	LRG1 MUTYH	2.90e-03	17	140	2	C0032580
Disease	MHPG measurement, 5-HIAA measurement	ADAM12 CLEC14A	2.90e-03	17	140	2	EFO_0005132, EFO_0005133
Disease	Adenocarcinoma of lung (disorder)	IRAK2 TTF1 FASN SLC15A2 MYO18B	3.08e-03	206	140	5	C0152013
Disease	glucose homeostasis measurement, acute insulin response measurement	SDK2 ASTN2	3.25e-03	18	140	2	EFO_0006831, EFO_0006896
Disease	Febrile seizure (within the age range of 3 months to 6 years)	SCN1A SCN2A	3.25e-03	18	140	2	HP_0002373
Disease	diet measurement, body mass index	ATP13A4 ATP13A5	4.02e-03	20	140	2	EFO_0004340, EFO_0008111
Disease	taurocholate measurement	ADAM12 ADGRA3	4.02e-03	20	140	2	EFO_0010538
Disease	left atrial function	SIX5 MYO18B	4.42e-03	21	140	2	EFO_0004294
Disease	Arthrogryposis	MAGEL2 DYNC1H1	4.42e-03	21	140	2	C0003886

Protein segments in the cluster

Peptide	Gene	Start	Entry
ESWLSVGPGGEITEL	TTF1	196	Q15361
WLSSPEALDGIVGTL	EXOC3L2	191	Q2M3D2
WSPDGSRLLFTVLGE	AAAS	336	Q9NRG9
SLSQGDPDAAIWLGD	ARHGEF10	1256	O15013
LTEDGLDLWGTVPTA	ATP13A5	491	Q4VNC0
SLASVPEGLWASLGQ	LRG1	271	P02750
LEASGSLESPVLEWS	CCDC187	711	A0A096LP49
LATLWAEPLSEEAGG	ALS2	956	Q96Q42
GEFTVIHALTGWLPE	ADGB	261	Q8N7X0
LGWGLPALVVATSVG	ADGRB3	986	O60242
DKTGTLTRDGLDLWG	ATP13A4	486	Q4VNC1
LISSIDPGAFWGLSS	ADGRA3	116	Q8IWK6
DPLGSTSRWLVDTGN	ARHGEF38	616	Q9NXL2
AGSSEWLAVDGLVSP	ATF4	56	P18848
DSLVGAGPASRLLWI	CD248	71	Q9HCU0
PFSDWGRLEAAILSG	FBXO4	16	Q9UKT5
SPLGATQLDTDGALW	AGRN	2001	O00468
GVALVESGWGSLLPT	APBA3	406	O96018
SVGSGDLWIPVKSFD	ADAM12	46	O43184
LVSWDIPGARALDNG	GLA	21	P06280
SLQDTLIWSFAGPIG	CELSR1	2606	Q9NYQ6
TGKASELERLALWPG	DNHD1	3946	Q96M86
STLLESTLEGAPEWA	C3orf36	61	Q3SXR2
TLSRVLWLSGLSEPG	CIAO2A	11	Q9H5X1
STLPALRESDIGWSG	ASTN2	71	O75129
PATLQGATDSLGLEW	DENND4A	1611	Q7Z401
RTAAGSSWEDPSLLE	RBM42	361	Q9BTD8
ALTGEGLPEALQSLW	ARL11	156	Q969Q4
LTWRLPDVSEAGGSG	FCHO1	816	O14526
IAKTLASEWLGSPGT	MUC16	381	Q8WXI7
STPGSAVQWAKDGLL	NPHS1	56	O60500
TLRAGESALELWGGP	DOK2	171	O60496
ASARLTVLWAEGLPG	IGDCC3	411	Q8IVU1
ALSAWEGPSTSRALG	MAGEL2	966	Q9UJ55
EWLRALSGGGSVASP	GIGYF1	11	O75420
AGWRALVEFLTPLGS	GLTPD2	106	A6NH11
TLPQGFTWDALDLGD	NMT1	151	P30419
ILWLSGAELGTLPAG	MFHAS1	231	Q9Y4C4
RETLLPWSGLSEGTG	IRAK2	506	O43187
RAAGAVGTLLSWPSS	FAM149A	86	A5PLN7
TAPSLDDDGWATVGV	LRIG3	796	Q6UXM1
DGVLSEWSGRSPSSL	FAM91A1	816	Q658Y4
LGNSSEGRTWDLPSA	KCNK7	81	Q9Y2U2
EGSKAVPWVILSDGD	CANT1	191	Q8WVQ1
VSALWEGLPGNLDAA	MMP19	326	Q99542
ALLLGAEPESWAAGA	PDE3B	91	Q13370
SVPWDDSLRGAVAGA	NES	1466	P48681
WASGLETLDSLGGVL	LEP	121	P41159
NWPLLEEVAAGSLRG	LINGO3	231	P0C6S8
LEVSPGDTGWDVFSL	TUBGCP3	626	Q96CW5
GWLPQETLELSGSRL	MRGPRX3	306	Q96LB0
FLSAPLIGALSDVWG	MFSD14A	86	Q96MC6
LSGVAGWRALTAPST	PAQR4	156	Q8N4S7
ELALLSTGVFIGWTP	OR5V1	196	Q9UGF6
PSLAQEELGWTAALG	GALE	311	Q14376
GPEWLRALSSGGSIT	GIGYF2	11	Q6Y7W6
GPSWAKALEEAGTIL	ANKZF1	281	Q9H8Y5
LAGPESLPSWALSDT	ENTR1	221	Q96C92
LSPISLAESWEDGSP	C1orf226	236	A1L170
FAGWSGVLDLILTPA	SLC49A4	296	Q96SL1
QAGLELLGSSDSPTW	EEF1AKMT2	261	Q5JPI9
ILSWEYLSGGSSIPE	HRH3	171	Q9Y5N1
SSLGAPVHLWGTEEV	DGKD	1136	Q16760
GTLDPNTREWTDGLF	DYNC1H1	2266	Q14204
AALGVTWGLDASSPL	HCFC1R1	21	Q9NWW0
TASLWSGPGLEDRGL	LAMB3	606	Q13751
ADLNSDGWPDLIVGA	ITGA7	371	Q13683
LLWAGSALLAPETGD	CELSR3	2261	Q9NYQ7
GPLVVLLDVGASAWA	GYS1	111	P13807
DAIPGKWTSQDSLLG	FASN	1586	P49327
LAKGSERSGLSEWLG	SLC13A2	431	Q13183
ERSGLSEWLGNKLTP	SLC13A2	436	Q13183
TPILGAAIADSWLGK	SLC15A2	96	Q16348
RSVLLSWEPGSDGLS	SDK2	1416	Q58EX2
LGALSGWAASDDPIE	SBSN	16	Q6UWP8
IPVSGALLTDWSDDT	IZUMO4	46	Q1ZYL8
GALSIWPLTQDLDSG	PPP4R1L	286	Q9P1A2
LWTELTGLAASSEPE	KIFC2	51	Q96AC6
SAPLIGALSDVWGRK	MFSD14C	96	Q5VZR4
SAPLIGALSDVWGRK	MFSD14B	96	Q5SR56
LRDTAPGTTLQWGAA	FOXQ1	286	Q9C009
RSWTGQELSPLAGED	MICAL2	1401	O94851
PTAVTLGTGAAWLGV	P2RX6	336	O15547
GTTSLFLPGASWIAD	OTOG	2771	Q6ZRI0
TSPSWGKGAELLLGD	MN1	1006	Q10571
GGWGLPSVDLDSLAV	MTX1	161	Q13505
ELTWSGSPRAGQLDS	NAV1	921	Q8NEY1
TLSWLPGDNGGSSIR	DSCAM	1396	O60469
NKWALLTDPGDIRTG	FER1L6	181	Q2WGJ9
IPAILIGAIGASTDW	SLC5A7	286	Q9GZV3
GLWLALVDGLVRSSP	SYS1	31	Q8N2H4
AGRAAAAVTWLLGEP	RETREG1	61	Q9H6L5
TRWGSPTSLEGELGA	NBEAL2	791	Q6ZNJ1
LEVLAGSPGVESFWE	NCAN	971	O14594
SLQAVPGAKDGTSLW	EPPK1	1131	P58107
TSAGWDGLLAPILNS	SCN9A	1696	Q15858
AVPVWSAGLELSAGT	SIX5	661	Q8N196
AGEVTDLLPGLAWSS	SMIM28	96	A0A1B0GU29
IGLIASSWGGTPIEA	SIAE	211	Q9HAT2
TLWGETALTAAAGRG	TANC1	1076	Q9C0D5
ALFRELISWGAPGSA	TAP1	111	Q03518
LISWGAPGSADSTRL	TAP1	116	Q03518
NSGLLAGLWEFPSVT	MUTYH	391	Q9UIF7
LVGSISEPGLGLLSW	POLR3H	186	Q9Y535
TTSAGWDGLLAPILN	SCN3A	1706	Q9NY46
VATWLKSDVGLGESP	SEC31B	496	Q9NQW1
GRELWSESPLGDLVS	IMPG2	446	Q9BZV3
AGERSPSLEAPSLWE	PROB1	466	E7EW31
GTPWALALLRTFDAG	RIPK4	6	P57078
GALWLLPALQEDSGT	IL1R2	91	P27930
TTSAGWDGLLAPILN	SCN1A	1721	P35498
GLPGWVLAVSATAAA	BRINP2	26	Q9C0B6
SALGKSPWLAGNELT	AIMP2	261	Q13155
QSTAAGLWALLGDPV	CLN8	76	Q9UBY8
PGLQRSLGVWSLEAA	CHST7	46	Q9NS84
LSSDPGGLESDTLQW	CLEC14A	116	Q86T13
TWIEGLTGLSIGPDF	CNN2	36	Q99439
DVWSSLRLPSGLGCS	PAICS	361	P22234
NISALTDLGGLDPVW	TSPAN17	51	Q96FV3
GLSRASAELWTPDSE	SECTM1	201	Q8WVN6
AWLSPKVLVSGAEDG	TEP1	1976	Q99973
STGSRDLGAALADWP	MINPP1	121	Q9UNW1
WVLAGSESLPVETLG	PBXIP1	11	Q96AQ6
EPIGSATDIWGAGVL	SPEG	3136	Q15772
GPVYSTWSALEGELA	SNX30	281	Q5VWJ9
LKPLLEAGTSGTWGS	UBA7	556	P41226
TAVIGLPSGLESWSF	PPM1A	41	P35813
GGEASTLSIWDLAAP	TLE4	551	Q04727
GERVSLLSPGWSALA	SPANXA2-OT1	101	Q8N9U9
TTSAGWDGLLAPILN	SCN2A	1711	Q99250
WGTEPTSGLGIILDS	NUP188	421	Q5SRE5
SGLRTDPLWELLVGS	PRRT4	91	C9JH25
DPLWELLVGSSGNSL	PRRT4	96	C9JH25
PAELVDSSGWATILA	VWA5A	716	O00534
EVTSEWAGSLDPISG	PPP1R3F	676	Q6ZSY5
ANSEPWTLDTLGGER	TACC2	1646	O95359
WPDSGSIAGGTLLTL	PKHD1L1	1161	Q86WI1
LERTWGPAAGLEAQL	SOCS7	46	O14512
PSRWGLEDEETSSGL	MYO18B	886	Q8IUG5
ALLGPESDGFLAWST	TMEM231	71	Q9H6L2
ATAPAALEGGWESSL	TMEM221	236	A6NGB7
LSGSDWLGTIAAGDI	GTF3C2	711	Q8WUA4
TPAVTLLLGDHGWVE	TRMT12	186	Q53H54
LLSGWLGSEDAAFVP	TMEM129	36	A0AVI4
STDDESNPLGRAGIW	TRIP12	1376	Q14669
GGEASTLSIWDLAAP	TLE2	521	Q04725
GAPLDSVGSDVWSTE	PPP6R3	696	Q5H9R7
PLTTDWRILSGKGSG	nan	21	Q6ZTI0
EVVDPSGGWATLLES	WASH6P	336	Q9NQA3
PVDSKVLWVAGLSGT	ZP4	501	Q12836
AGLLDLPDASVNGWS	TCIRG1	676	Q13488
VSTGLESPGGLAVDW	LRP4	506	O75096
VDTSLESPAGLAIDW	LRP4	811	O75096