Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionstructural constituent of skin epidermis

KRT6A KRT6B KRT6C TUFT1

1.37e-0543684GO:0030280
GeneOntologyMolecularFunctionstructural constituent of cytoskeleton

KRT6A KRT6B ANK2 EPB41L4B DMD

8.13e-05130685GO:0005200
DomainPumilio_RNA-bd

PUM2 PUM1

1.16e-052642IPR033712
DomainPUM-HD

PUM2 PUM1

3.46e-053642IPR033133
DomainPUF

PUM2 PUM1

3.46e-053642PF00806
DomainPUM_HD

PUM2 PUM1

3.46e-053642PS50303
DomainVDCC_L_bsu

CACNB1 CACNB4

6.90e-054642IPR000584
DomainPumilio_RNA-bd_rpt

PUM2 PUM1

6.90e-054642IPR001313
DomainVGCC_beta4Aa_N

CACNB1 CACNB4

6.90e-054642PF12052
DomainPUM

PUM2 PUM1

6.90e-054642PS50302
DomainPumilio

PUM2 PUM1

6.90e-054642SM00025
DomainKeratin_2_head

KRT6A KRT6B KRT6C

7.38e-0524643IPR032444
DomainKeratin_2_head

KRT6A KRT6B KRT6C

7.38e-0524643PF16208
DomainKeratin_II

KRT6A KRT6B KRT6C

9.43e-0526643IPR003054
DomainMACPF_CS

C6 C8B

1.72e-046642IPR020863
DomainMACPF_2

C6 C8B

2.40e-047642PS51412
DomainMACPF_1

C6 C8B

2.40e-047642PS00279
DomainLDLR_class-A_CS

C6 C8B SORL1

3.46e-0440643IPR023415
DomainLdl_recept_a

C6 C8B SORL1

4.91e-0445643PF00057
DomainMAC_perforin

C6 C8B

5.11e-0410642IPR001862
DomainLDLRA_1

C6 C8B SORL1

5.95e-0448643PS01209
DomainMACPF

C6 C8B

6.23e-0411642PF01823
DomainLDLRA_2

C6 C8B SORL1

6.32e-0449643PS50068
DomainLDrepeatLR_classA_rpt

C6 C8B SORL1

6.32e-0449643IPR002172
DomainLDLa

C6 C8B SORL1

6.32e-0449643SM00192
Domainzf-C2H2_6

ZNF473 ZFP64 SNAI2 E4F1 PRDM2 ZNF646

7.12e-04314646PF13912
DomainMACPF

C6 C8B

7.46e-0412642SM00457
DomainMACPF

C6 C8B

7.46e-0412642IPR020864
DomainARM-type_fold

GBF1 AP1B1 DOCK11 PUM2 HEATR5B PUM1

1.06e-03339646IPR016024
DomainIntermediate_filament_CS

KRT6A KRT6B KRT6C

1.32e-0363643IPR018039
DomainFilament

KRT6A KRT6B KRT6C

1.86e-0371643SM01391
DomainIF

KRT6A KRT6B KRT6C

1.93e-0372643PS00226
DomainFilament

KRT6A KRT6B KRT6C

2.01e-0373643PF00038
Domain-

HIVEP1 ZNF473 ZFP64 SNAI2 E4F1 ZNF583 PRDM2 ZNF646

2.15e-036796483.30.160.60
DomainIF

KRT6A KRT6B KRT6C

2.26e-0376643IPR001664
Domainzf-C2H2

HIVEP1 ZNF473 ZFP64 SNAI2 E4F1 ZNF583 PRDM2 ZNF646

2.44e-03693648PF00096
DomainZnf_C2H2/integrase_DNA-bd

HIVEP1 ZNF473 ZFP64 SNAI2 E4F1 ZNF583 PRDM2 ZNF646

2.46e-03694648IPR013087
DomainGuanylate_kin

CACNB1 CACNB4

3.56e-0326642PF00625
DomainGK/Ca_channel_bsu

CACNB1 CACNB4

3.56e-0326642IPR008145
DomainGuanylate_kin-like_dom

CACNB1 CACNB4

3.56e-0326642IPR008144
DomainGuKc

CACNB1 CACNB4

3.56e-0326642SM00072
DomainZINC_FINGER_C2H2_2

HIVEP1 ZNF473 ZFP64 SNAI2 E4F1 ZNF583 PRDM2 ZNF646

4.81e-03775648PS50157
DomainZINC_FINGER_C2H2_1

HIVEP1 ZNF473 ZFP64 SNAI2 E4F1 ZNF583 PRDM2 ZNF646

4.89e-03777648PS00028
DomainZnf_C2H2-like

HIVEP1 ZNF473 ZFP64 SNAI2 E4F1 ZNF583 PRDM2 ZNF646

5.64e-03796648IPR015880
DomainZnf_C2H2

HIVEP1 ZNF473 ZFP64 SNAI2 E4F1 ZNF583 PRDM2 ZNF646

6.03e-03805648IPR007087
DomainZnF_C2H2

HIVEP1 ZNF473 ZFP64 SNAI2 E4F1 ZNF583 PRDM2 ZNF646

6.16e-03808648SM00355
Domain-

AP1B1 PUM2 HEATR5B PUM1

7.07e-032226441.25.10.10
DomainEGF_3

ADAM18 C6 C8B SORL1

8.61e-03235644PS50026
Pubmed

Genetic variants in pachyonychia congenita-associated keratins increase susceptibility to tooth decay.

KRT6A KRT6B KRT6C

7.47e-09369329357356
Pubmed

Cloning and characterization of multiple human genes and cDNAs encoding highly related type II keratin 6 isoforms.

KRT6A KRT6B KRT6C

7.47e-0936937543104
Pubmed

Pachyonychia Congenita

KRT6A KRT6B KRT6C

7.45e-08569320301457
Pubmed

Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain.

GBF1 RAPGEF5 PUM2 TSC1 RB1CC1

6.83e-07836959039502
Pubmed

Three ways to make a vesicle.

GBF1 AP1B1 PUM1 SEC13

1.81e-064469411252894
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

FLII CACNB1 CACNB4 ANK2 HOOK1 AP1B1 CENPF DOCK11 TJAP1 ANKRD28 TSC1

2.92e-06963691128671696
Pubmed

Breeding of the gad-mdx mouse: influence of genetically induced denervation on dystrophic muscle fibers.

UCHL1 DMD

3.88e-0626928007658
Pubmed

A reporter transgene based on a human keratin 6 gene promoter is specifically expressed in the periderm of mouse embryos.

KRT6A KRT6B

3.88e-06269211118885
Pubmed

Autophagy inhibition prevents lymphatic malformation progression to lymphangiosarcoma by decreasing osteopontin and Stat3 signaling.

TSC1 RB1CC1

3.88e-06269236813768
Pubmed

Expression of MK6a dominant-negative and C-terminal mutant transgenes in mice has distinct phenotypic consequences in the epidermis and hair follicle.

KRT6A KRT6B

3.88e-06269210550543
Pubmed

The mouse keratin 6 isoforms are differentially expressed in the hair follicle, footpad, tongue and activated epidermis.

KRT6A KRT6B

3.88e-06269210550545
Pubmed

Cloning and comparative sequence analysis of PUM1 and PUM2 genes, human members of the Pumilio family of RNA-binding proteins.

PUM2 PUM1

3.88e-06269212459267
Pubmed

Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins.

PUM2 PUM1

3.88e-06269229165587
Pubmed

PUMILIO-mediated translational control of somatic cell cycle program promotes folliculogenesis and contributes to ovarian cancer progression.

PUM2 PUM1

3.88e-06269235507203
Pubmed

Bespoke RNA recognition by Pumilios.

PUM2 PUM1

3.88e-06269226517885
Pubmed

Mouse Pum1 and Pum2 genes, members of the Pumilio family of RNA-binding proteins, show differential expression in fetal and adult hematopoietic stem cells and progenitors.

PUM2 PUM1

3.88e-06269212667987
Pubmed

Genome-wide comparison of human keratinocyte and squamous cell carcinoma responses to UVB irradiation: implications for skin and epithelial cancer.

PUM2 PUM1

3.88e-06269212771951
Pubmed

Alternate modes of cognate RNA recognition by human PUMILIO proteins.

PUM2 PUM1

3.88e-06269221397187
Pubmed

The two functional keratin 6 genes of mouse are differentially regulated and evolved independently from their human orthologs.

KRT6A KRT6B

3.88e-0626929790766
Pubmed

Collapse of the keratin filament network through the expression of mutant keratin 6c observed in a case of focal plantar keratoderma.

KRT6A KRT6C

3.88e-06269223662636
Pubmed

Structures of the murine genes for the beta1- and beta4-subunits of the voltage-dependent calcium channel.

CACNB1 CACNB4

3.88e-06269214500989
Pubmed

A Quantitative and Predictive Model for RNA Binding by Human Pumilio Proteins.

PUM2 PUM1

3.88e-06269231078383
Pubmed

Expression of BTBD7 in primary salivary adenoid cystic carcinoma and correlation with Slug and prognosis.

BTBD7 SNAI2

3.88e-06269227540976
Pubmed

Discovery of a novel murine keratin 6 (K6) isoform explains the absence of hair and nail defects in mice deficient for K6a and K6b.

KRT6A KRT6B

3.88e-06269211489919
Pubmed

Delayed wound healing in keratin 6a knockout mice.

KRT6A KRT6B

3.88e-06269210866680
Pubmed

Introducing a null mutation in the mouse K6alpha and K6beta genes reveals their essential structural role in the oral mucosa.

KRT6A KRT6B

3.88e-06269210953016
Pubmed

Principles of mRNA control by human PUM proteins elucidated from multimodal experiments and integrative data analysis.

PUM2 PUM1

3.88e-06269232753408
Pubmed

The complete cDNA and deduced amino acid sequence of a type II mouse epidermal keratin of 60,000 Da: analysis of sequence differences between type I and type II keratins.

KRT6A KRT6B

3.88e-0626926207530
Pubmed

PUMILIO proteins promote colorectal cancer growth via suppressing p21.

PUM2 PUM1

3.88e-06269235338151
Pubmed

Cytokeratins mediate epithelial innate defense through their antimicrobial properties.

KRT6A KRT6B

3.88e-06269223006328
Pubmed

Effects of PUMILIO1 and PUMILIO2 knockdown on cardiomyogenic differentiation of human embryonic stem cells culture.

PUM2 PUM1

3.88e-06269232437472
Pubmed

Autophagic lipid metabolism sustains mTORC1 activity in TSC-deficient neural stem cells.

TSC1 RB1CC1

3.88e-06269232577608
Pubmed

Comparative analysis of mRNA targets for human PUF-family proteins suggests extensive interaction with the miRNA regulatory system.

PUM2 PUM1

3.88e-06269218776931
Pubmed

Characterization of RNP Networks of PUM1 and PUM2 Post-Transcriptional Regulators in TCam-2 Cells, a Human Male Germ Cell Model.

PUM2 PUM1

3.88e-06269232316190
Pubmed

Keratin expression provides novel insight into the morphogenesis and function of the companion layer in hair follicles.

KRT6A KRT6B

1.16e-05369217170733
Pubmed

Antagonistic and cooperative AGO2-PUM interactions in regulating mRNAs.

PUM2 PUM1

1.16e-05369230333515
Pubmed

Human Pumilio proteins directly bind the CCR4-NOT deadenylase complex to regulate the transcriptome.

PUM2 PUM1

1.16e-05369233397688
Pubmed

NORAD: Defender of the Genome.

PUM2 PUM1

1.16e-05369227157388
Pubmed

Overcoming functional redundancy to elicit pachyonychia congenita-like nail lesions in transgenic mice.

KRT6A KRT6B

1.16e-05369215601842
Pubmed

Cytokeratin 5/6 expression in bladder cancer: association with clinicopathologic parameters and prognosis.

KRT6A KRT6B

1.16e-05369229587848
Pubmed

A role for keratins in supporting mitochondrial organization and function in skin keratinocytes.

KRT6A KRT6B

1.16e-05369232213122
Pubmed

A novel function of human Pumilio proteins in cytoplasmic sensing of viral infection.

PUM2 PUM1

1.16e-05369225340845
Pubmed

PUMILIO/FOXP1 signaling drives expansion of hematopoietic stem/progenitor and leukemia cells.

PUM2 PUM1

1.16e-05369228232582
Pubmed

Noncoding RNA NORAD Regulates Genomic Stability by Sequestering PUMILIO Proteins.

PUM2 PUM1

1.16e-05369226724866
Pubmed

Expression of Cre recombinase in chondrocytes causes abnormal craniofacial and skeletal development.

TSC1 RB1CC1

1.16e-05369235526258
Pubmed

Mice expressing a mutant Krt75 (K6hf) allele develop hair and nail defects resembling pachyonychia congenita.

KRT6A KRT6B

1.16e-05369217851587
Pubmed

COP9 signalosome component CSN-5 stabilizes PUF proteins FBF-1 and FBF-2 in Caenorhabditis elegans germline stem and progenitor cells.

PUM2 PUM1

1.16e-05369238427913
Pubmed

A small deletion hotspot in the type II keratin gene mK6irs1/Krt2-6g on mouse chromosome 15, a candidate for causing the wavy hair of the caracul (Ca) mutation.

KRT6A KRT6B

1.16e-05369214573483
Pubmed

Loss of keratin 6 (K6) proteins reveals a function for intermediate filaments during wound repair.

KRT6A KRT6B

1.16e-05369214568992
Pubmed

Identification of a cloned sequence activated during multi-stage carcinogenesis in mouse skin.

KRT6A KRT6B

1.16e-0536921713533
Pubmed

Regional expression and subcellular localization of the voltage-gated calcium channel β subunits in the developing mouse brain.

CACNB1 CACNB4

1.16e-05369222737983
Pubmed

Pumilio facilitates miRNA regulation of the E2F3 oncogene.

PUM2 PUM1

1.16e-05369222345517
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

FLII KRT6A KRT6B CACNB4 ANK2 AP1B1 EPB41L4B UCHL1 OSBPL9 TSC1 DMD SEC13

2.26e-051431691237142655
Pubmed

The light peak of the electroretinogram is dependent on voltage-gated calcium channels and antagonized by bestrophin (best-1).

CACNB1 CACNB4

2.32e-05469216636205
Pubmed

Mammalian Pum1 and Pum2 Control Body Size via Translational Regulation of the Cell Cycle Inhibitor Cdkn1b.

PUM2 PUM1

2.32e-05469230811992
Pubmed

Keratin 6 regulates collective keratinocyte migration by altering cell-cell and cell-matrix adhesion.

KRT6A KRT6B

2.32e-05469230389720
Pubmed

Mapping of the azh locus to mouse chromosome 4.

HOOK1 H6PD

2.32e-0546921552159
Pubmed

A review of the clinical phenotype of 254 patients with genetically confirmed pachyonychia congenita.

KRT6A KRT6B

2.32e-05469222264670
Pubmed

Btbd7 regulates epithelial cell dynamics and branching morphogenesis.

BTBD7 SNAI2

2.32e-05469220671187
Pubmed

Mouse models in preclinical studies for pachyonychia congenita.

KRT6A KRT6B

2.32e-05469216250208
Pubmed

The transcription factor Slug represses p16Ink4a and regulates murine muscle stem cell aging.

SNAI2 DMD

2.32e-05469231189923
Pubmed

Phosphorylation of human keratin 8 in vivo at conserved head domain serine 23 and at epidermal growth factor-stimulated tail domain serine 431.

KRT6A KRT6C

2.32e-0546929054461
Pubmed

Ankyrin-B interactions with spectrin and dynactin-4 are required for dystrophin-based protection of skeletal muscle from exercise injury.

ANK2 DMD

2.32e-05469221186323
Pubmed

Mutations of calcium channel beta subunit genes in mice.

CACNB1 CACNB4

2.32e-05469210494839
Pubmed

Reciprocal interactions regulate targeting of calcium channel beta subunits and membrane expression of alpha1 subunits in cultured hippocampal neurons.

CACNB1 CACNB4

2.32e-05469219996312
Pubmed

Target RNA motif and target mRNAs of the Quaking STAR protein.

PUM2 PUM1

2.32e-05469216041388
Pubmed

Secretory protein trafficking and organelle dynamics in living cells.

GBF1 AP1B1 PUM1 SEC13

2.54e-058569411031247
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

FLII KRT6A KRT6C CENPF UCHL1 MYO1B RB1CC1 HEATR5B PUM1 ADAR

3.30e-051024691024711643
Pubmed

Airway hillocks are injury-resistant reservoirs of unique plastic stem cells.

KRT6A KRT6B

3.86e-05569238693267
Pubmed

The four terminal components of the complement system are C-mannosylated on multiple tryptophan residues.

C6 C8B

3.86e-05569210551839
Pubmed

Diversity and developmental expression of L-type calcium channel beta2 proteins and their influence on calcium current in murine heart.

CACNB1 CACNB4

3.86e-05569219723630
Pubmed

An Important Role of Pumilio 1 in Regulating the Development of the Mammalian Female Germline.

PUM2 PUM1

3.86e-05569227170441
Pubmed

Role for keratins 6 and 17 during wound closure in embryonic mouse skin.

KRT6A KRT6B

3.86e-05569212557214
Pubmed

Three epidermal and one simple epithelial type II keratin genes map to human chromosome 12.

KRT6A KRT6B

3.86e-0556921713141
Pubmed

Regulation of voltage-gated calcium channel activity by the Rem and Rad GTPases.

CACNB1 CACNB4

3.86e-05569214623965
Pubmed

PUM1 and PUM2 exhibit different modes of regulation for SIAH1 that involve cooperativity with NANOS paralogues.

PUM2 PUM1

3.86e-05569230269240
Pubmed

The diagnostic utility of D2-40, calretinin, CK5/6, desmin and MOC-31 in the differentiation of mesothelioma from adenocarcinoma in pleural effusion cytology.

KRT6A KRT6B

3.86e-05569223075894
Pubmed

Hair follicle stem cells regulate retinoid metabolism to maintain the self-renewal niche for melanocyte stem cells.

KRT6A KRT6B

3.86e-05569231898934
Pubmed

Role of the beta(2) subunit of voltage-dependent calcium channels in the retinal outer plexiform layer.

CACNB1 CACNB4

3.86e-05569211980879
Pubmed

An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan.

ANK2 DMD

3.86e-05569219109891
Pubmed

The RNA-binding protein Musashi-1 is produced in the developing and adult mouse eye.

PUM2 PUM1

5.79e-05669217768378
Pubmed

ELF a beta-spectrin is a neuronal precursor cell marker in developing mammalian brain; structure and organization of the elf/beta-G spectrin gene.

ANK2 DMD

5.79e-05669212149647
Pubmed

Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9.

C6 C8B

5.79e-05669222832194
Pubmed

Identification of 14-3-3sigma mutation causing cutaneous abnormality in repeated-epilation mutant mouse.

KRT6A KRT6B

5.79e-05669216239341
Pubmed

Pumilio proteins utilize distinct regulatory mechanisms to achieve complementary functions required for pluripotency and embryogenesis.

PUM2 PUM1

5.79e-05669232198202
Pubmed

Identification of functional variants for cleft lip with or without cleft palate in or near PAX7, FGFR2, and NOG by targeted sequencing of GWAS loci.

KRT6A KRT6B

5.79e-05669225704602
Pubmed

p63(+)Krt5(+) distal airway stem cells are essential for lung regeneration.

KRT6A KRT6B

5.79e-05669225383540
Pubmed

Keratin 6 is not essential for mammary gland development.

KRT6A KRT6B

5.79e-05669216790075
Pubmed

beta subunit reshuffling modifies N- and P/Q-type Ca2+ channel subunit compositions in lethargic mouse brain.

CACNB1 CACNB4

5.79e-05669210328888
Pubmed

Staufen 1 is expressed by neural precursor cells in the developing murine cortex but is dispensable for NPC self-renewal and neuronal differentiation in vitro.

PUM2 PUM1

8.09e-05769234678304
Pubmed

CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers.

C6 C8B

8.09e-05769230552328
Pubmed

Involvement of the c-jun N-terminal kinases JNK1 and JNK2 in complement-mediated cell death.

C6 C8B

8.09e-05769219864026
Pubmed

Deciphering TGF-β3 function in medial edge epithelium specification and fusion during mouse secondary palate development.

KRT6A KRT6B

8.09e-05769225104574
Pubmed

Post-transcriptional gene expression control by NANOS is up-regulated and functionally important in pRb-deficient cells.

PUM2 PUM1

8.09e-05769225100735
Pubmed

Frizzled6 deficiency disrupts the differentiation process of nail development.

KRT6A KRT6B

8.09e-05769223439395
Pubmed

Prediction of local recurrence, distant metastases, and death after breast-conserving therapy in early-stage invasive breast cancer using a five-biomarker panel.

KRT6A KRT6B

8.09e-05769219720911
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

FLII KRT6A GBF1 EPB41L4B DOCK11 PUM2 PUM1 ADAR

9.27e-0572469836232890
Pubmed

Activated Braf induces esophageal dilation and gastric epithelial hyperplasia in mice.

KRT6A KRT6B UCHL1

9.99e-054569328973166
Pubmed

An in vivo comparative study of sonic, desert and Indian hedgehog reveals that hedgehog pathway activity regulates epidermal stem cell homeostasis.

KRT6A KRT6B

1.08e-04869215371305
Pubmed

Grainyhead-like factor Get1/Grhl3 regulates formation of the epidermal leading edge during eyelid closure.

KRT6A KRT6B

1.08e-04869218485343
InteractionFOXI2 interactions

GBF1 PBX2 PUM1 ADAR SORL1

9.53e-0753685int:FOXI2
InteractionKDM1A interactions

FLII KRT6A KRT6B HIVEP1 CENPF SPZ1 UCHL1 SNAI2 ANKRD28 TSC1 RB1CC1 TUFT1 PRDM2

1.33e-059416813int:KDM1A
Cytoband8q11

SNAI2 RB1CC1

3.33e-0566928q11
Cytoband12q13.13

KRT6A KRT6B KRT6C

1.45e-046769312q13.13
Cytoband1p32

STIL C8B

7.63e-04276921p32
CytobandEnsembl 112 genes in cytogenetic band chr1p32

HOOK1 OSBPL9 C8B

1.68e-03155693chr1p32
CytobandEnsembl 112 genes in cytogenetic band chr2q23

RND3 CACNB4

2.92e-0353692chr2q23
CytobandEnsembl 112 genes in cytogenetic band chr1q22

CLK2 KHDC4

5.17e-0371692chr1q22
CytobandEnsembl 112 genes in cytogenetic band chr8q11

SNAI2 RB1CC1

5.91e-0376692chr8q11
GeneFamilyCalcium voltage-gated channel subunits|Membrane associated guanylate kinases

CACNB1 CACNB4 CARD11

3.85e-0526463904
GeneFamilyKeratins, type II

KRT6A KRT6B KRT6C

4.32e-0527463609
GeneFamilyAnkyrin repeat domain containing

ANK2 ANKRD28 ANKRD6 ANKRD18B ANKRD30BL

3.61e-04242465403
GeneFamilyCalcium voltage-gated channel subunits

CACNB1 CACNB4

1.98e-0326462253
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

HIVEP1 ZNF473 ZFP64 SNAI2 E4F1 ZNF583 ZNF646

2.10e-0371846728
GeneFamilyComplement system|Sushi domain containing

C6 C8B

3.78e-0336462492
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

SPZ1 ANKRD28 RB1CC1

1.09e-02181463694
CoexpressionGSE13411_NAIVE_VS_IGM_MEMORY_BCELL_UP

KRT6B ZNF473 GVINP1 SNAI2 KHDC4 SORL1

1.31e-05196696M3239
CoexpressionCHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN

RND3 KRT6A KRT6B ARHGEF28 SNAI2 OSBPL9 MYO1B DMD

2.65e-05457698M14507
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRN

B3GALT2 RND3 ANK2 HOOK1 RAPGEF5 UCHL1 TSC1

2.86e-05335697M39065
CoexpressionONDER_CDH1_TARGETS_2_DN

KRT6A KRT6B HOOK1 EPB41L4B RAPGEF5 MYO1B DMD SORL1

3.38e-05473698M4306
CoexpressionSNF5_DN.V1_DN

CACNB4 CLCA1 ARHGEF28 UCHL1 DIO2

5.97e-05157695M2715
CoexpressionCUI_TCF21_TARGETS_2_DN

B3GALT2 HIVEP1 GVINP1 RAPGEF5 PUM2 MYO1B H6PD CALCRL PBX2 HEATR5B

7.64e-058546910M1533
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

HIVEP1 GBF1 CENPF PUM2 ANKRD28 MYO1B STIL DMD RB1CC1 PUM1

7.78e-058566910M4500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_1000

RND3 KRT6A CLCA1 ANK2 EPB41L4B SNAI2 PUM2 MYO1B ANKRD6 PBX2 KHDC4 SORL1

1.69e-058506912gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1

FLII CENPF CLK2 BTBD7 OSBPL9 TSC1 RB1CC1 ANKRD6 HEATR5B KHDC4 ZNF583

4.00e-057806911Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K1
CoexpressionAtlasAravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_500_k-means-cluster#4

KRT6A KRT6B KRT6C SNAI2

4.06e-0559694Arv_EB-LF_500_K4
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ARHGEF28 HOOK1 RAPGEF5 DMD ANKRD30BL SORL1

4.88e-071896967659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCellE16.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_immature_-_proliferative|E16.5-samps / Age Group, Lineage, Cell class and subclass

KRT6A KRT6B ANK2 DIO2 ZNF583

2.26e-0613669596370f0e3abf1c9ec7a91595b5d0f97ac2ab4b78
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Keratinizing_Cervical_Squamous_Cell_Carcinoma|TCGA-Cervix / Sample_Type by Project: Shred V9

RND3 KRT6A KRT6B KRT6C SNAI2

5.63e-06164695de1646dbcf2a10b48e021acf7dc63e803e6a47ce
ToppCellMid-temporal_gyrus_(MTG)|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DMD ANKRD6 CCDC171 ANKRD18B ANKRD30BL

8.39e-06178695ad187db4c40b9078d54dd915c143e0172b2f47b8
ToppCelldroplet-Heart-nan-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GVINP1 RAPGEF5 BTBD7 MYO1B CALCRL

9.10e-0618169592d44892bb15771f0ab5fe61879b204b0acbd9b3
ToppCellPCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating1_(8)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ARHGEF28 HOOK1 EPB41L4B CENPF TUFT1

1.06e-05187695c2940aec30b3c2c113f6a65126dc6f1969cf301e
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ARHGEF28 HOOK1 EPB41L4B TUFT1 SORL1

1.12e-051896955d9da836ce4308b8458bb3be3871a0aca734b6cd
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma|TCGA-Lung / Sample_Type by Project: Shred V9

KRT6A KRT6B KRT6C ZFP64 SNAI2

1.12e-05189695aa4f7d7a5196e5ae481ebc2549de8e3f0ef6e6be
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ARHGEF28 HOOK1 EPB41L4B ANKRD30BL SORL1

1.15e-05190695625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ANK2 HOOK1 RAPGEF5 DMD ANKRD30BL

1.21e-05192695b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ANK2 HOOK1 RAPGEF5 ANKRD30BL CFAP65

1.27e-05194695b30379f8dc41c86c746af9930541fbb4819d8fa0
ToppCellPCW_10-12-Epithelial|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ARHGEF28 HOOK1 EPB41L4B DMD ANKRD30BL

1.34e-051966959bfb31ff3e4f2c0a9405c418c86bfec5dbca23e2
ToppCellBronchus_Control_(B.)|World / Sample group, Lineage and Cell type

KRT6A KRT6B HIVEP1 ANKRD18B PRDM2

1.37e-05197695b6dff2ee108813e18657e2d8cf850e2423f8c8e9
ToppCellPSB|World / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

HOOK1 EPB41L4B C6 DMD NEK11

1.40e-051986954e6b0d1abc55d7a0d89bd7ecf0f13dc5bed66626
ToppCelldistal-1-Epithelial-Proliferating_Basal|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KRT6A KRT6B KRT6C CENPF SNAI2

1.44e-0519969593450257180d918c310bca7b5defc74390c48091
ToppCell10x3'2.3-week_14-16-Endothelial-stroma-tip_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ARHGEF28 RAPGEF5 KCNJ8 MYO1B CALCRL

1.44e-051996951c69395c9305b6ecb0a826d46c8e8ec95795ad6d
ToppCellHematolymphoid-Microglia-TYROBP----L1-3|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

CACNB4 ATP8B4 AP1B1 DOCK11 SORL1

1.47e-05200695a20dce14f94777687aad57d6fbe3258ad376f63f
ToppCell10x5'v1-week_14-16-Endothelial-stroma-tip_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ARHGEF28 RAPGEF5 KCNJ8 MYO1B CALCRL

1.47e-0520069577ac1aa73c16a4f595ff01c6b4e171e0b8fed1e6
ToppCelldistal-Epithelial-Proliferating_Basal|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KRT6A KRT6B KRT6C CENPF SNAI2

1.47e-0520069525cc494ef831511840d8c02ec1bd086635cc7edd
ToppCellHematolymphoid-Microglia-TYROBP--|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

CACNB4 ATP8B4 AP1B1 DOCK11 SORL1

1.47e-05200695dc344b3ec51d506952e38f0b3a7795d65f9dd4eb
ToppCellHematolymphoid-Microglia-TYROBP-|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

CACNB4 ATP8B4 AP1B1 DOCK11 SORL1

1.47e-052006953bba5219453322198e8fdb0921d5f8c403598751
ToppCellHematolymphoid-Microglia|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

CACNB4 ATP8B4 AP1B1 DOCK11 SORL1

1.47e-0520069521bcca3b670fe9bac034aef2275d3de4a9a73e2b
ToppCelldistal-Epithelial-Proliferating_Basal-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KRT6A KRT6B KRT6C CENPF SNAI2

1.47e-05200695cc31e8c28d01e6757c5dd7f485db6acf7409a47e
ToppCellHematolymphoid-Microglia-TYROBP---|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

CACNB4 ATP8B4 AP1B1 DOCK11 SORL1

1.47e-05200695a8646d0fca99f10827c2d2a12e584660ef7155f1
ToppCellHematolymphoid-Microglia-TYROBP|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

CACNB4 ATP8B4 AP1B1 DOCK11 SORL1

1.47e-0520069533036d21c1c82109284473a515c4f890b33fdd5c
ToppCell(24)_B_cell_cycling|World / shred on Cell_type and subtype

CENPF SNAI2 STIL DMD ANKRD30BL

1.55e-05202695a7c9b6b173701348ba35fbb975e0bdd3c1f1d5fe
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

RAPGEF5 ADAM18 SORL1 CFAP65

7.40e-0514469408005be9e3367f78ef27e125d9cce5ca53f4bd2d
ToppCell367C-Lymphocytic-NK_cells-NK_cell_E|367C / Donor, Lineage, Cell class and subclass (all cells)

ATP8B4 ZNF473 CARD11 E4F1

8.45e-05149694f18bddc84b064f3d57a1281d5172c404d87f25da
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

CACNB1 ARHGEF28 ZNF473 RAPGEF5

9.13e-051526947a1072315cce71eefe2d32149a107d5648999968
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

KCNJ8 SNAI2 DIO2 CALCRL

9.60e-05154694511923b27469ea20f8bd82a9ec27119a6e884644
ToppCellfacs-Lung-nan-3m-Epithelial-type_I_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF28 EPB41L4B PBX2 TUFT1

1.28e-0416669411b0ae82b3068ef91715dbdd49fe8e9791b4a480
ToppCellfacs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF28 EPB41L4B PBX2 TUFT1

1.28e-04166694fcc1aec31ebd39432d4cb284dc8fadf34e3c566a
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-6|TCGA-Bladder / Sample_Type by Project: Shred V9

KRT6A KRT6B KRT6C MYO1B

1.44e-041716940e78389f8f3d54570a6deb3dd307b865b46307e9
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATP8B4 ZNF473 CENPF CARD11

1.44e-04171694846a9acfff0bf0a9baf65dc07b7d7a9217ed6598
ToppCelldroplet-Lung-nan-18m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF473 CENPF MASTL STIL

1.47e-04172694e495efd25aec60b97ac2b5aa861651bd73174a17
ToppCell5'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLCA1 HOOK1 TUFT1 CFAP65

1.54e-04174694e7cca4b6a3935fad61cf2a3d9984ab1ffa1a9447
ToppCell3'_v3-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Lymphocytic-T|bone_marrow / Manually curated celltypes from each tissue

CACNB4 ATP8B4 CALCRL C8B

1.54e-041746941e289b26e2c29dbad15b712a999b96c391a26129
ToppCell5'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet-Goblet_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLCA1 HOOK1 TUFT1 CFAP65

1.54e-04174694ad5b56f0ace6455c033834b931ec870cc0dc9290
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

B3GALT2 ARHGEF28 SNAI2 DMD

1.60e-041766940710689e66deba179b0a8038cdd56b4834984f12
ToppCelldroplet-Lung-18m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZNF473 CENPF MASTL STIL

1.60e-04176694b17317ac41d3215db55a38cbd3366c0947f7a2a3
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-5|TCGA-Lung / Sample_Type by Project: Shred V9

KRT6A KRT6B KRT6C SNAI2

1.64e-04177694a0c7d08469c513cecf87777c19876884f1511570
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CACNB4 DIO2 MYO1B SORL1

1.64e-04177694c9e8149639551a4c8daa90fcb2b895fdcff2e2ba
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

B3GALT2 ARHGEF28 SNAI2 DMD

1.68e-041786946f61490d79cd1727ed2d5cc673823dd4efdafac1
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CENPF RAPGEF5 STIL CALCRL

1.68e-04178694ea10117026021c959ffc871fc377cdb3e161d264
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RND3 KHDC4 TUFT1 SORL1

1.71e-041796946e965e424eebef50f0202cff75f458be395cfca1
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

B3GALT2 ARHGEF28 SNAI2 DMD

1.71e-041796941ac79c82c52fa95bb4e170ab20fec0f648db2134
ToppCelldroplet-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CENPF UCHL1 ANKRD28 CALCRL

1.79e-041816942c44c41b4e8a75ebdbaeb0c6cc5a03f17c44758c
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCA1 MYO1B HEATR5B CCDC171

1.79e-04181694709e9c7a60d5f98635b99895ce30bb87a9f7376d
ToppCelldroplet-Heart-nan-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GVINP1 RAPGEF5 MYO1B CALCRL

1.82e-0418269481279877b920b5a1bc991a07d3031d6458700fe3
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK11 KCNJ8 MYO1B DMD

1.86e-041836948a799807fbf24456a9811e0c64068187940a2f71
ToppCelldroplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZNF473 CENPF MASTL STIL

1.86e-04183694e91f00b75d43ee6293fdd4a129b789cd95f8d11a
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-3|TCGA-Lung / Sample_Type by Project: Shred V9

KRT6A KRT6B ZFP64 SNAI2

1.90e-04184694ea4ccebe2d54279fcc517e4f0bfa652b91a808bb
ToppCellfacs-Heart-RV-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNB4 KCNJ8 MYO1B SORL1

1.90e-041846949c20b50f8d6ac689d41d5440c835f9db8d04758b
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

B3GALT2 ARHGEF28 KCNJ8 DMD

1.90e-04184694ca35a3d2b536c8b2bf5c4d635605e5a3ae94a428
ToppCellCOPD-Myeloid-Macrophage_Alveolar|World / Disease state, Lineage and Cell class

RND3 ANKRD28 C8B HEATR5B

1.90e-041846947fd0b227c3750ffb80e41e92c60fcce46656be14
ToppCellfacs-Heart-RV-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNB4 KCNJ8 MYO1B SORL1

1.90e-0418469431dbe6119a3bcd266ae5e9b340c853d9ff680dce
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_EGR3|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

B3GALT2 ARHGEF28 KCNJ8 SNAI2

1.90e-04184694219bd3b8daa0a713fb6a8a5e1bb35cdb85bb7727
ToppCellPBMC-Mild-cDC_9|Mild / Compartment, Disease Groups and Clusters

CACNB1 CENPF DDX60L ADAR

1.90e-041846942e0c9a2c40c892a2d435eafb31f1f838de9baf15
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK11 DMD C8B ANKRD6

1.94e-041856944e40d3103ebf4a7066b7ce300b6ef700ba0e2863
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RND3 KCNJ8 SNAI2 DMD

1.94e-041856949878392d79734ab5bb977d7f4f5e2e079b9a5353
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_EGR3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

B3GALT2 ARHGEF28 KCNJ8 DMD

1.98e-0418669477b09af860183606a1775eba921e2071e4a7dd4e
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK11 MYO1B C8B ANKRD6

1.98e-041866944bb54043f944a979db91bde9a86dd66f498c7658
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ARHGEF28 HOOK1 EPB41L4B ANKRD30BL

1.98e-04186694bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ARHGEF28 HOOK1 EPB41L4B ANKRD30BL

2.02e-04187694db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KRT6A KRT6B KRT6C PBX2

2.02e-04187694a6a112689d1c9049f57935ad9d2f4955538427de
ToppCelldroplet-Lung-nan-18m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCA1 ARHGEF28 KCNJ8 ANKRD6

2.06e-04188694a6ed43fdd42d681c9fbb2fb368947ab7e41d8d7c
ToppCellPCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

HOOK1 EPB41L4B DMD ANKRD30BL

2.06e-041886940d86044bc340e3efb90d0022dd299873639d831c
ToppCelldroplet-Lung-nan-18m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCA1 ARHGEF28 KCNJ8 ANKRD6

2.06e-0418869454550313db78b3b5b572fa1e67092c8f6f33aab5
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-naive_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP8B4 DIO2 ANKRD28 REV1

2.06e-04188694e079a3873cf442e98ff41a240c80b80995aace11
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

RND3 ARHGEF28 ANKRD28 HEATR5B

2.06e-04188694d7a9fb5b021e127b8d927658a55a71098d513b5c
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma|TCGA-Cervix / Sample_Type by Project: Shred V9

KRT6A KRT6B KRT6C SNAI2

2.11e-04189694533c302df467d13ab639232daf4f8cafb808260b
ToppCellControl-Myeloid-Macrophage_Alveolar|Control / Disease state, Lineage and Cell class

RND3 ARHGEF28 DOCK11 HEATR5B

2.11e-04189694937e876122bc4b94372a4104e9c1a9068c232018
ToppCelldroplet-Limb_Muscle-nan-3m-Endothelial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT6A KRT6B CLK2 KCNJ8

2.11e-0418969416a4c92dd7a0d60f3691bd3130a091a9a54730f1
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGEF28 ANK2 UCHL1 CCDC171

2.11e-041896943f5522be3e24dcdb6272f18cee2f239dfdeff9ad
ToppCelldroplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CLCA1 ARHGEF28 KCNJ8 ANKRD6

2.15e-04190694e80d66ba0d5c263e94c1ab0b89d1dc7b837af3e1
ToppCelldroplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CLCA1 ARHGEF28 KCNJ8 ANKRD6

2.15e-04190694f32d66c0e74e0a2a23ecb857c4daf0d8573a806c
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_intermediate_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ARHGEF28 HOOK1 DMD ANKRD30BL

2.15e-04190694c95032bb3ee2b3d40fdf48016acb46d6f78a48a6
ToppCelldroplet-Lung-18m-Endothelial-lymphatic_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CLCA1 ARHGEF28 KCNJ8 ANKRD6

2.15e-04190694b79ffd05806244a9790cd04c66fb4f92c824e69f
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CLCA1 ANK2 KCNJ8 ANKRD6

2.15e-04190694a1514d2186eb4fe569971ab22dc0c17d353fb94a
ToppCellIPF-Myeloid-Macrophage_Alveolar|Myeloid / Disease state, Lineage and Cell class

RND3 ARHGEF28 DOCK11 HEATR5B

2.15e-041906942592765016f291565697265800a232b2edef3792
ToppCellCOPD-Myeloid-Macrophage_Alveolar|Myeloid / Disease state, Lineage and Cell class

RND3 ARHGEF28 ANKRD28 HEATR5B

2.15e-041906949fc763d65470ba8858b973689c4d4358faab7dd3
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CLCA1 ANK2 KCNJ8 ANKRD6

2.15e-041906940bb954a94317cfc742b9b6221bb80f8baa6d3ff1
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CLCA1 ANK2 KCNJ8 ANKRD6

2.15e-0419069426e2237f65cb43723c5da853831b40df2982d6e4
ToppCell10x5'v1-week_12-13-Endothelial-stroma-tip_EC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ARHGEF28 RAPGEF5 KCNJ8 CALCRL

2.19e-04191694cf1a67b7c0d5c0dc5d4d59faf9d9b1a3a1fb00e0
ToppCellfacs-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCA1 ANK2 KCNJ8 ANKRD6

2.19e-0419169448823a97c38263f2c6e58348214f5b62773a6368
ToppCellControl-Myeloid-Macrophage_Alveolar|Myeloid / Disease state, Lineage and Cell class

RND3 ARHGEF28 DOCK11 HEATR5B

2.19e-04191694a7bb8aba9c59c037d995a77928cc7b4d5cbb82b9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RAPGEF5 KCNJ8 MYO1B DMD

2.19e-041916947b0d42a877540dbb346a76a62403e0d5d3e07fa6
ToppCellfacs-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCA1 ANK2 KCNJ8 ANKRD6

2.19e-041916940eedc66e967b1837ce2c14f8c14b3c1eba868c76
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RAPGEF5 KCNJ8 MYO1B DMD

2.19e-04191694cd854b9c426924fdc84bf7f411f6dea447143e79
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGEF28 ANK2 UCHL1 CCDC171

2.24e-04192694d8f5df2c2a50e567f24ebecc8033ac97ba89d9c5
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

HIVEP1 ARHGEF28 RB1CC1 PUM1

2.24e-04192694916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ARHGEF28 HOOK1 EPB41L4B SORL1

2.24e-04192694b7c01e12b3e9be960a741b08835f1dfff65d0d47
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DOCK11 RAPGEF5 KCNJ8 DMD

2.24e-041926945000440dc1ed17e7474d340921bdff945646f27e
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_CTGF^high_distal_(3)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ARHGEF28 HOOK1 EPB41L4B ANKRD30BL

2.28e-04193694ab78fb1603ea6f720ba2d30148fe65dccf271fe1
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

HIVEP1 ARHGEF28 RB1CC1 PUM1

2.28e-04193694e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^medium_distal_(2)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ARHGEF28 HOOK1 EPB41L4B SORL1

2.28e-041936944b8202fcfe639a73f69a13f48fc3601ade256346
ToppCellNS-critical-d_07-13-Epithelial-Squamous|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RND3 KRT6A DIO2 TUFT1

2.33e-0419469453a34843d529ef395deb27086f71f7049a087bab
ToppCellNS-critical-d_0-4-Epithelial-Squamous|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RND3 KRT6A KRT6B TUFT1

2.33e-04194694614d0c25b56957c70f397abb169fd2a860eb1c06
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGEF28 ANK2 UCHL1 CCDC171

2.33e-041946945bd0f739aa75f387cca7c3b2686493ee2d1ee968
ToppCellPCW_07-8.5-Epithelial|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ARHGEF28 HOOK1 ANKRD30BL SORL1

2.33e-04194694f63ceedb88a9abc8644ee94adfd541e7817c1e3a
DrugSC-791

KRT6A KRT6B KRT6C

5.29e-076693CID010291510
DrugPHA-00745360 [351320-33-7]; Up 200; 10uM; MCF7; HT_HG-U133A

KRT6B RAPGEF5 ZFP64 TJAP1 C6 PRDM2 ZNF646

2.16e-061966973907_UP
DrugLycorine hydrochloride [2188-68-3]; Up 200; 12.4uM; MCF7; HT_HG-U133A

RND3 RAPGEF5 ZFP64 SNAI2 MYO1B TUFT1

1.20e-051686964365_UP
Drugclobestasol propionate

KRT6A KRT6B KRT6C

1.76e-0517693CID000002791
DrugGW8510; Down 200; 10uM; PC3; HT_HG-U133A

RND3 CENPF PUM2 PUM1 PRDM2 REV1

1.90e-051826967085_DN
DrugCD-III

KRT6A KRT6B KRT6C UCHL1

2.02e-0553694CID000066693
Drugdithranol

KRT6A KRT6B KRT6C

2.10e-0518693CID000002202
DrugPyrantel tartrate [33401-94-4]; Up 200; 11.2uM; MCF7; HT_HG-U133A

RAPGEF5 BTBD7 UCHL1 H6PD PRDM2 ZNF646

2.80e-051956962260_UP
DrugTinidazole [19387-91-8]; Up 200; 16.2uM; MCF7; HT_HG-U133A

CACNB1 CLCA1 UCHL1 KCNJ8 ZFP64 ZNF646

2.88e-051966964370_UP
DrugOlux

KRT6A KRT6B KRT6C

2.93e-0520693CID000032797
DrugN1-acetylspermidine

KRT6A KRT6B KRT6C

2.93e-0520693CID000000496
DrugCotinine (-) [486-56-6]; Up 200; 22.6uM; MCF7; HT_HG-U133A

KRT6B CACNB1 RAPGEF5 KCNJ8 ZFP64 H6PD

2.96e-051976965246_UP
DrugAllantoin [97-59-6]; Up 200; 25.2uM; PC3; HT_HG-U133A

ARHGEF28 ZNF473 HOOK1 RAPGEF5 RB1CC1 NEK11

2.96e-051976961800_UP
DrugCefuroxime sodium salt [56238-63-2]; Down 200; 9uM; PC3; HT_HG-U133A

ARHGEF28 CENPF RAPGEF5 BTBD7 KCNJ8 TJAP1

3.14e-051996965787_DN
DrugRanitidine hydrochloride [66357-59-3]; Up 200; 11.4uM; MCF7; HT_HG-U133A

CLCA1 BTBD7 ZFP64 TJAP1 MYO1B PRDM2

3.14e-051996962251_UP
DrugCyclizine hydrochloride [303-25-3]; Up 200; 13.2uM; PC3; HT_HG-U133A

FLII HOOK1 RAPGEF5 BTBD7 ZFP64 PRDM2

3.14e-051996965100_UP
DrugChloroprene

RND3 GBF1 CLCA1 ARHGEF28 RAPGEF5 UCHL1 SNAI2 MYO1B CARD11 STIL CALCRL RB1CC1 PUM1 REV1

4.36e-0513486914ctd:D002737
DrugMK-6

KRT6A KRT6B KRT6C

5.15e-0524693CID005283547
DrugBhg-(2-1)fuc

KRT6A KRT6B KRT6C

5.84e-0525693CID005287784
Drugbetamethasone valerate

KRT6A KRT6B KRT6C

8.27e-0528693CID000016533
DrugAC1L1KPQ

KRT6A KRT6B KRT6C RB1CC1

9.30e-0578694CID000005602
Drug2-Formyl-Protoporphryn Ix

KRT6A KRT6B KRT6C

1.13e-0431693CID011963946
DrugAGN 193109

KRT6A KRT6B KRT6C

1.13e-0431693CID000177238
Drugplakin

KRT6A KRT6B KRT6C DMD

1.13e-0482694CID000018752
Drug4,4'-thiodiphenol

KRT6A KRT6B KRT6C

1.24e-0432693CID000017570
DiseaseMalignant neoplasm of breast

ANK2 HOOK1 CENPF ZFP64 SNAI2 H6PD DMD RB1CC1 ADAR SORL1 ZNF646

2.42e-0510746611C0006142
DiseasePachyonychia Congenita, Jadassohn Lewandowsky Type

KRT6A KRT6B

2.95e-054662C1706595
Diseasepachyonychia congenita (is_implicated_in)

KRT6A KRT6B

2.95e-054662DOID:0050449 (is_implicated_in)
DiseasePachyonychia congenita syndrome

KRT6A KRT6B

2.95e-054662cv:C0265334
DiseasePachyonychia Congenita, Type 2 (disorder)

KRT6A KRT6B

2.95e-054662C1721007
DiseasePachyonychia Congenita

KRT6A KRT6B

4.91e-055662C0265334
DiseaseCalcinosis

SNAI2 C6 DMD

1.15e-0442663C0006663
DiseaseMicrocalcification

SNAI2 C6 DMD

1.15e-0442663C0521174
DiseaseTumoral calcinosis

SNAI2 C6 DMD

1.15e-0442663C0263628
DiseaseBrugada Syndrome (disorder)

ANK2 KCNJ8

1.32e-0324662C1142166
Diseaseobesity (implicated_via_orthology)

FLII PUM2 TSC1 PUM1

1.39e-03215664DOID:9970 (implicated_via_orthology)
DiseaseAtaxia

CACNB4 PUM1

1.43e-0325662C0004134
Diseaseintellectual disability (is_implicated_in)

TSC1 DMD

2.06e-0330662DOID:1059 (is_implicated_in)
Diseasebrain aneurysm

CARD11 CCDC171 PRDM2

2.10e-03113663EFO_0003870
Diseaseprogressive supranuclear palsy

HOOK1 SEC13

2.20e-0331662MONDO_0019037

Protein segments in the cluster

PeptideGeneStartEntry
HLNVQIAASEKLAQC

CACNB1

366

Q02641
AFQLCQAVKFLHDNK

CLK2

271

P49760
LACVQPHKNANKSDA

ADAM18

551

Q9Y3Q7
AKKHQAFLVETCENN

CCDC171

406

Q6TFL3
TCAQALQHLDKNNLK

GVINP1

46

Q7Z2Y8
LKLSVHKSQQNDCAN

MASTL

491

Q96GX5
SKCVNLAKDNEVLHQ

ANKRD18B

771

A2A2Z9
LHIAAANKAVKCAEA

ANKRD28

111

O15084
AAVCVAKLHDINAQL

AP1B1

141

Q10567
NFSNGHVVCEKKQQL

ATP8B4

726

Q8TF62
VAAAETAKHQAKCNI

DMD

3301

P11532
HLNVQLVAADKLAQC

CACNB4

356

O00305
AKNKAGNTALHLACQ

ANKRD6

136

Q9Y2G4
KDQNGNHVVQKCIEC

PUM2

846

Q8TB72
KHCIVLLQIAKDQSN

OSBPL9

171

Q96SU4
KESLQCSNCNANVHK

ARHGEF28

676

Q8N1W1
LCTAQHKQKEEQAVS

ANK2

3686

Q01484
KCTTAKQELANNLHV

RB1CC1

436

Q8TDY2
QSLDEAQAKKHALNC

PBX2

66

P40425
EVKKHQNQEDRCAAA

DIO2

181

Q92813
DHVKKQCASLQAAIA

KRT6C

396

P48668
DKKACSAIHAVNLRN

FLII

556

Q13045
FIAKSGACNLAHKNI

KCNJ8

36

Q15842
DHVKKQCANLQAAIA

KRT6A

396

P02538
QAVAKCAQLLVSIKH

CFAP65

336

Q6ZU64
SEKQADKCLNFLQDH

DDX60L

931

Q5H9U9
DHVKKQCANLQAAIA

KRT6B

396

P04259
KNLDCQKEAAHIINA

NEK11

306

Q8NG66
KDQNGNHVVQKCIEC

PUM1

966

Q14671
HLQQNKHNACANAAK

B3GALT2

396

O43825
KHNACANAAKEKAGR

B3GALT2

401

O43825
HFAECVKQAKGVRQQ

HEATR5B

806

Q9P2D3
KNNCKISADFHVDLN

DOCK11

406

Q5JSL3
AVCAHSKKQGKQEAA

ADAR

771

P55265
ALHNDQEACKAKEQN

CENPF

2456

P49454
CKFLAEKCLNNQQLH

C6

816

P13671
NQNCLDEELKAHKAV

BTBD7

266

Q9P203
HCQAKVLNSLTQQEK

GBF1

591

Q92538
AAAKKLCENLLQTVH

KHDC4

306

Q7Z7F0
EDFVQHKIQKACQRA

E4F1

71

Q66K89
GCAINCEKKQEHIQN

HOOK1

126

Q9UJC3
ILFKNQACCVQSEKH

H6PD

371

O95479
DHVKCNILKAQLENA

EPB41L4B

606

Q9H329
QCNVNTHEKVKTALN

CALCRL

126

Q16602
NIEAVAAKNKHCLLE

CARD11

1041

Q9BXL7
TLNNVHACAKNDFKI

C8B

371

P07358
CKKEFAFLCNLQQHQ

PRDM2

1196

Q13029
HVATLACVNKTNKNV

RND3

191

P61587
EVKKINNAHTIGCNA

SEC13

141

P55735
KVQVQCLSKAHNTND

SORL1

1626

Q92673
DVRAFCNQLKHKATQ

NEPRO

311

Q6NW34
HAIEAEKFQCNLCNK

SNAI2

121

O43623
IKIAAHCKAQRNLNS

RAPGEF5

421

Q92565
NANAVDKFKCVHQQL

ANKRD30BL

196

A7E2S9
INKDDVQHKQVCFSR

CLCA1

716

A8K7I4
DCNLAVQLLKCNKSH

TJAP1

171

Q5JTD0
AKLQEAKRQHQSDCV

TUFT1

181

Q9NNX1
KKNAHNVDHASVLAC

STIL

1016

Q15468
KLDSAIHLCNNAVQK

TTLL8

441

A6PVC2
KANNKVCHTELLLSQ

TSC1

816

Q92574
QVCAVQQAESHGDKK

REV1

956

Q9UBZ9
CSKQLFNAAALKNHV

ZNF646

406

O15015
LNKKACNTQFNIHVA

SPZ1

401

Q9BXG8
CKQQFNNLDAFVAHK

ZFP64

36

Q9NTW7
HQKRAKDENGAVCAT

HIVEP1

1761

P15822
KECRKAFSQNAHLAQ

ZNF583

271

Q96ND8
KCFEKNEAIQAAHDA

UCHL1

131

P09936
NSHFANKKCQDVIVA

ZW10

396

O43264
CGKAFAQKANLTQHQ

ZNF473

791

Q8WTR7
KKAAHIFNEALVCHQ

MYO1B

601

O43795