Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	olfactory receptor activity	OR5AC2 OR4A8 OR5AU1 OR5C1 OR1L6 OR5T2 OR5A1 OR5M11 OR10G9 OR10G8 OR2L13 OR6P1 GPR148 OR10G7 OR10G4 OR51F1	7.03e-11	431	89	16	GO:0004984
GeneOntologyMolecularFunction	G protein-coupled receptor activity	FZD7 OR5AC2 OR4A8 OR5AU1 GPR39 OR5C1 OR1L6 OR5T2 OR5A1 OR5M11 OR10G9 OR10G8 OR2L13 OR6P1 GPR148 OR10G7 OR10G4 OR51F1	5.60e-08	884	89	18	GO:0004930
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	FZD7 CHRNA6 OR5AC2 OR4A8 OR5AU1 GPR39 OR5C1 OR1L6 OR5T2 OR5A1 OR5M11 OR10G9 OR10G8 OR2L13 OR6P1 PLXNA1 PLXNA2 GPR148 OR10G7 OR10G4 OR51F1	3.67e-07	1353	89	21	GO:0004888
GeneOntologyMolecularFunction	odorant binding	OR5AC2 OR5AU1 OR5C1 OR5T2 OR5A1 OR5M11 GPR148	1.59e-06	127	89	7	GO:0005549
GeneOntologyMolecularFunction	glucan 1,4-alpha-glucosidase activity	MGAM MGAM2	1.96e-05	2	89	2	GO:0004339
GeneOntologyMolecularFunction	bone sialoprotein binding	ANXA2 ANXA2P2	1.96e-05	2	89	2	GO:0044730
GeneOntologyMolecularFunction	phospholipase A2 inhibitor activity	ANXA2 ANXA2P2	1.95e-04	5	89	2	GO:0019834
GeneOntologyMolecularFunction	alpha-1,4-glucosidase activity	MGAM MGAM2	1.95e-04	5	89	2	GO:0004558
GeneOntologyMolecularFunction	histone H3K4me/H3K4me2/H3K4me3 demethylase activity	KDM5C KDM5D	2.91e-04	6	89	2	GO:0034647
GeneOntologyMolecularFunction	alpha-glucosidase activity	MGAM MGAM2	4.07e-04	7	89	2	GO:0090599
GeneOntologyMolecularFunction	histone H3K4 demethylase activity	KDM5C KDM5D	5.41e-04	8	89	2	GO:0032453
GeneOntologyMolecularFunction	protein-glutamic acid ligase activity	TTLL4 TTLL1	8.64e-04	10	89	2	GO:0070739
GeneOntologyMolecularFunction	tubulin-glutamic acid ligase activity	TTLL4 TTLL1	8.64e-04	10	89	2	GO:0070740
GeneOntologyMolecularFunction	semaphorin receptor activity	PLXNA1 PLXNA2	1.26e-03	12	89	2	GO:0017154
GeneOntologyMolecularFunction	phospholipase inhibitor activity	ANXA2 ANXA2P2	1.48e-03	13	89	2	GO:0004859
GeneOntologyMolecularFunction	S100 protein binding	ANXA2 ANXA2P2	1.99e-03	15	89	2	GO:0044548
GeneOntologyMolecularFunction	glucosidase activity	MGAM MGAM2	1.99e-03	15	89	2	GO:0015926
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR5AC2 OR4A8 OR5AU1 OR5C1 OR1L6 OR5T2 OR5A1 OR5M11 OR10G9 OR10G8 OR2L13 OR6P1 GPR148 OR10G7 OR10G4 OR51F1	1.81e-11	432	84	16	GO:0050911
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR5AC2 OR4A8 OR5AU1 OR5C1 OR1L6 CASP4 OR5T2 OR5A1 OR5M11 OR10G9 OR10G8 OR2L13 OR6P1 GPR148 OR10G7 OR10G4 OR51F1	3.14e-11	524	84	17	GO:0009593
GeneOntologyBiologicalProcess	sensory perception of smell	OR5AC2 OR4A8 OR5AU1 OR5C1 OR1L6 OR5T2 OR5A1 OR5M11 OR10G9 OR10G8 OR2L13 OR6P1 GPR148 OR10G7 OR10G4 OR51F1	5.39e-11	465	84	16	GO:0007608
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR5AC2 OR4A8 OR5AU1 OR5C1 OR1L6 OR5T2 OR5A1 OR5M11 OR10G9 OR10G8 OR2L13 OR6P1 GPR148 OR10G7 OR10G4 OR51F1	1.00e-10	485	84	16	GO:0050907
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR5AC2 OR4A8 OR5AU1 OR5C1 OR1L6 OR5T2 OR5A1 OR5M11 OR10G9 OR10G8 OR2L13 OR6P1 GPR148 OR10G7 OR10G4 OR51F1	5.82e-10	547	84	16	GO:0007606
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR5AC2 OR4A8 OR5AU1 OR5C1 OR1L6 OR5T2 OR5A1 OR5M11 OR10G9 OR10G8 OR2L13 OR6P1 GPR148 OR10G7 OR10G4 OR51F1	1.42e-09	582	84	16	GO:0050906
GeneOntologyBiologicalProcess	detection of stimulus	OR5AC2 OR4A8 OR5AU1 OR5C1 OR1L6 CASP4 OR5T2 OR5A1 OR5M11 OR10G9 OR10G8 OR2L13 OR6P1 GPR148 OR10G7 OR10G4 OR51F1	4.21e-09	722	84	17	GO:0051606
GeneOntologyBiologicalProcess	sensory perception	OR5AC2 OR4A8 OR5AU1 OR5C1 OR1L6 OR5T2 OR5A1 OR5M11 OR10G9 OR10G8 SLC1A3 OR2L13 OR6P1 GPR148 OR10G7 OR10G4 OR51F1	1.22e-06	1072	84	17	GO:0007600
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	FZD7 OR5AC2 OR4A8 OR5AU1 GPR39 OR5C1 OR1L6 OR5T2 OR5A1 OR5M11 OR10G9 OR10G8 OR2L13 OR6P1 GPR148 OR10G7 OR10G4 OR51F1	1.03e-05	1395	84	18	GO:0007186
GeneOntologyBiologicalProcess	positive regulation of low-density lipoprotein particle receptor binding	ANXA2 ANXA2P2	1.64e-05	2	84	2	GO:1905597
GeneOntologyBiologicalProcess	positive regulation of receptor-mediated endocytosis involved in cholesterol transport	ANXA2 ANXA2P2	4.90e-05	3	84	2	GO:1905602
GeneOntologyBiologicalProcess	negative regulation of low-density lipoprotein particle receptor catabolic process	ANXA2 ANXA2P2	4.90e-05	3	84	2	GO:0032804
GeneOntologyBiologicalProcess	positive regulation of low-density lipoprotein particle clearance	ANXA2 ANXA2P2	9.78e-05	4	84	2	GO:1905581
GeneOntologyBiologicalProcess	negative regulation of receptor catabolic process	ANXA2 ANXA2P2	9.78e-05	4	84	2	GO:2000645
GeneOntologyBiologicalProcess	regulation of blastocyst development	TTLL4 TTLL1	9.78e-05	4	84	2	GO:0120222
GeneOntologyBiologicalProcess	positive regulation of intracellular cholesterol transport	ANXA2 ANXA2P2	9.78e-05	4	84	2	GO:0032385
GeneOntologyBiologicalProcess	positive regulation of intracellular sterol transport	ANXA2 ANXA2P2	9.78e-05	4	84	2	GO:0032382
GeneOntologyBiologicalProcess	positive regulation of plasma membrane repair	ANXA2 ANXA2P2	1.63e-04	5	84	2	GO:1905686
GeneOntologyBiologicalProcess	regulation of low-density lipoprotein particle receptor binding	ANXA2 ANXA2P2	1.63e-04	5	84	2	GO:1905595
GeneOntologyBiologicalProcess	positive regulation of intracellular lipid transport	ANXA2 ANXA2P2	1.63e-04	5	84	2	GO:0032379
GeneOntologyBiologicalProcess	positive regulation of low-density lipoprotein receptor activity	ANXA2 ANXA2P2	2.43e-04	6	84	2	GO:1905599
GeneOntologyBiologicalProcess	regulation of low-density lipoprotein particle receptor catabolic process	ANXA2 ANXA2P2	3.40e-04	7	84	2	GO:0032803
GeneOntologyBiologicalProcess	low-density lipoprotein particle receptor catabolic process	ANXA2 ANXA2P2	3.40e-04	7	84	2	GO:0032802
GeneOntologyBiologicalProcess	low-density lipoprotein receptor particle metabolic process	ANXA2 ANXA2P2	3.40e-04	7	84	2	GO:0032799
GeneOntologyBiologicalProcess	regulation of receptor-mediated endocytosis involved in cholesterol transport	ANXA2 ANXA2P2	4.52e-04	8	84	2	GO:1905600
GeneOntologyBiologicalProcess	regulation of plasma membrane repair	ANXA2 ANXA2P2	4.52e-04	8	84	2	GO:1905684
GeneOntologyBiologicalProcess	positive regulation of receptor binding	ANXA2 ANXA2P2	4.52e-04	8	84	2	GO:1900122
GeneOntologyBiologicalProcess	receptor-mediated endocytosis involved in cholesterol transport	ANXA2 ANXA2P2	8.80e-04	11	84	2	GO:0090118
GeneOntologyCellularComponent	AnxA2-p11 complex	ANXA2 ANXA2P2	5.36e-05	3	89	2	GO:1990665
GeneOntologyCellularComponent	PCSK9-AnxA2 complex	ANXA2 ANXA2P2	5.36e-05	3	89	2	GO:1990667
GeneOntologyCellularComponent	Mon1-Ccz1 complex	CCZ1B CCZ1	1.78e-04	5	89	2	GO:0035658
GeneOntologyCellularComponent	NLRP1 inflammasome complex	CASP12 CASP4	2.66e-04	6	89	2	GO:0072558
GeneOntologyCellularComponent	myelin sheath adaxonal region	ANXA2 ANXA2P2	3.71e-04	7	89	2	GO:0035749
GeneOntologyCellularComponent	late endosome	CCZ1B SLC29A3 CLCN6 CCZ1 ANXA2 ANXA2P2 WDR81	7.14e-04	348	89	7	GO:0005770
GeneOntologyCellularComponent	pinosome	ANXA2 ANXA2P2	9.62e-04	11	89	2	GO:0044352
GeneOntologyCellularComponent	macropinosome	ANXA2 ANXA2P2	9.62e-04	11	89	2	GO:0044354
GeneOntologyCellularComponent	late endosome membrane	SLC29A3 CLCN6 ANXA2 ANXA2P2 WDR81	1.01e-03	179	89	5	GO:0031902
GeneOntologyCellularComponent	semaphorin receptor complex	PLXNA1 PLXNA2	1.36e-03	13	89	2	GO:0002116
GeneOntologyCellularComponent	Schmidt-Lanterman incisure	ANXA2 ANXA2P2	2.34e-03	17	89	2	GO:0043220
GeneOntologyCellularComponent	canonical inflammasome complex	CASP12 CASP4	2.62e-03	18	89	2	GO:0061702
GeneOntologyCellularComponent	tricarboxylic acid cycle heteromeric enzyme complex	OGDHL SUCLA2	2.62e-03	18	89	2	GO:0045239
GeneOntologyCellularComponent	alpha-ketoacid dehydrogenase complex	PDK2 OGDHL	2.62e-03	18	89	2	GO:0045240
GeneOntologyCellularComponent	compact myelin	ANXA2 ANXA2P2	3.57e-03	21	89	2	GO:0043218
GeneOntologyCellularComponent	lysosomal membrane	CCZ1B SLC29A3 CLCN6 CCZ1 ANXA2 ANXA2P2 WDR81	3.57e-03	462	89	7	GO:0005765
GeneOntologyCellularComponent	lytic vacuole membrane	CCZ1B SLC29A3 CLCN6 CCZ1 ANXA2 ANXA2P2 WDR81	3.57e-03	462	89	7	GO:0098852
Domain	Olfact_rcpt	OR5AC2 OR5AU1 OR5C1 OR1L6 OR5T2 OR5A1 OR5M11 OR10G9 OR10G8 OR2L13 OR6P1 OR10G7 OR10G4	2.11e-08	393	84	13	IPR000725
Domain	GPCR_Rhodpsn_7TM	OR5AC2 OR5AU1 GPR39 OR5C1 OR1L6 OR5T2 OR5A1 OR5M11 OR10G9 OR10G8 OR2L13 OR6P1 GPR148 OR10G7 OR10G4	2.67e-07	670	84	15	IPR017452
Domain	7tm_1	OR5AC2 OR5AU1 GPR39 OR5C1 OR1L6 OR5T2 OR5A1 OR5M11 OR10G9 OR10G8 OR2L13 OR6P1 GPR148 OR10G7 OR10G4	3.05e-07	677	84	15	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR5AC2 OR5AU1 GPR39 OR5C1 OR1L6 OR5T2 OR5A1 OR5M11 OR10G9 OR10G8 OR2L13 OR6P1 GPR148 OR10G7 OR10G4	3.54e-07	685	84	15	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR5AC2 OR5AU1 GPR39 OR5C1 OR1L6 OR5T2 OR5A1 OR5M11 OR10G9 OR10G8 OR2L13 OR6P1 GPR148 OR10G7 OR10G4	3.96e-07	691	84	15	PS50262
Domain	GPCR_Rhodpsn	OR5AC2 OR5AU1 GPR39 OR5C1 OR1L6 OR5T2 OR5A1 OR5M11 OR10G9 OR10G8 OR2L13 OR6P1 GPR148 OR10G7 OR10G4	4.03e-07	692	84	15	IPR000276
Domain	DUF1712	CCZ1B CCZ1	2.00e-05	2	84	2	PF08217
Domain	DUF1712_fun	CCZ1B CCZ1	2.00e-05	2	84	2	IPR013176
Domain	-	KDM5C ARID5B KDM5D	3.84e-05	15	84	3	1.10.150.60
Domain	BRIGHT	KDM5C ARID5B KDM5D	3.84e-05	15	84	3	SM00501
Domain	ARID_dom	KDM5C ARID5B KDM5D	3.84e-05	15	84	3	IPR001606
Domain	ARID	KDM5C ARID5B KDM5D	3.84e-05	15	84	3	PS51011
Domain	ARID	KDM5C ARID5B KDM5D	3.84e-05	15	84	3	PF01388
Domain	Ig_E-set	POGLUT3 ASCC3 SNRNP200 PLXNA1 PLXNA2	1.06e-04	104	84	5	IPR014756
Domain	Lys_sp_deMease-like_dom	KDM5C KDM5D	1.19e-04	4	84	2	IPR013637
Domain	PLU-1	KDM5C KDM5D	1.19e-04	4	84	2	PF08429
Domain	Sec63	ASCC3 SNRNP200	1.19e-04	4	84	2	PF02889
Domain	Sec63	ASCC3 SNRNP200	1.19e-04	4	84	2	SM00973
Domain	Sec63-dom	ASCC3 SNRNP200	1.19e-04	4	84	2	IPR004179
Domain	NtCtMGAM_N	MGAM MGAM2	1.19e-04	4	84	2	PF16863
Domain	Gal_mutarotase_N	MGAM MGAM2	1.19e-04	4	84	2	IPR031727
Domain	zf-C5HC2	KDM5C KDM5D	1.98e-04	5	84	2	PF02928
Domain	Znf_C5HC2	KDM5C KDM5D	1.98e-04	5	84	2	IPR004198
Domain	Glyco_hydro_31_AS	MGAM MGAM2	2.96e-04	6	84	2	IPR030458
Domain	Sema	SEMA6D PLXNA1 PLXNA2	3.60e-04	31	84	3	SM00630
Domain	Semap_dom	SEMA6D PLXNA1 PLXNA2	3.60e-04	31	84	3	IPR001627
Domain	ATP_grasp_subdomain_2	TTLL4 TTLL1 SUCLA2	3.60e-04	31	84	3	IPR013816
Domain	Sema	SEMA6D PLXNA1 PLXNA2	3.60e-04	31	84	3	PF01403
Domain	SEMA	SEMA6D PLXNA1 PLXNA2	3.60e-04	31	84	3	PS51004
Domain	PSI	SEMA6D PLXNA1 PLXNA2	3.96e-04	32	84	3	PF01437
Domain	Plexin_repeat	SEMA6D PLXNA1 PLXNA2	3.96e-04	32	84	3	IPR002165
Domain	Glyco_hydro_31	MGAM MGAM2	4.14e-04	7	84	2	IPR000322
Domain	Pept_C14A_CASP1-typ	CASP12 CASP4	4.14e-04	7	84	2	IPR017350
Domain	Glyco_hydro_31	MGAM MGAM2	4.14e-04	7	84	2	PF01055
Domain	GLYCOSYL_HYDROL_F31_1	MGAM MGAM2	4.14e-04	7	84	2	PS00129
Domain	Trefoil	MGAM MGAM2	5.50e-04	8	84	2	PF00088
Domain	Plexin_cytopl	PLXNA1 PLXNA2	7.05e-04	9	84	2	PF08337
Domain	Plexin_cytoplasmic_RasGAP_dom	PLXNA1 PLXNA2	7.05e-04	9	84	2	IPR013548
Domain	Plexin	PLXNA1 PLXNA2	7.05e-04	9	84	2	IPR031148
Domain	P_TREFOIL_2	MGAM MGAM2	7.05e-04	9	84	2	PS51448
Domain	PD	MGAM MGAM2	7.05e-04	9	84	2	SM00018
Domain	JmjN	KDM5C KDM5D	8.79e-04	10	84	2	SM00545
Domain	JMJN	KDM5C KDM5D	8.79e-04	10	84	2	PS51183
Domain	JmjN	KDM5C KDM5D	8.79e-04	10	84	2	PF02375
Domain	JmjN	KDM5C KDM5D	8.79e-04	10	84	2	IPR003349
Domain	PSI	SEMA6D PLXNA1 PLXNA2	1.02e-03	44	84	3	IPR016201
Domain	-	MGAM MGAM2	1.07e-03	11	84	2	4.10.110.10
Domain	PSI	SEMA6D PLXNA1 PLXNA2	1.16e-03	46	84	3	SM00423
Domain	Caspase_cys_AS	CASP12 CASP4	1.28e-03	12	84	2	IPR033139
Domain	P_trefoil_dom	MGAM MGAM2	1.28e-03	12	84	2	IPR000519
Domain	Caspase_his_AS	CASP12 CASP4	1.28e-03	12	84	2	IPR016129
Domain	CASPASE_P10	CASP12 CASP4	1.28e-03	12	84	2	PS50207
Domain	CASPASE_CYS	CASP12 CASP4	1.28e-03	12	84	2	PS01122
Domain	Pept_C14_p10	CASP12 CASP4	1.28e-03	12	84	2	IPR002138
Domain	CASc	CASP12 CASP4	1.51e-03	13	84	2	SM00115
Domain	Pept_C14A	CASP12 CASP4	1.51e-03	13	84	2	IPR015917
Domain	TTL	TTLL4 TTLL1	1.51e-03	13	84	2	PS51221
Domain	TTL/TTLL_fam	TTLL4 TTLL1	1.51e-03	13	84	2	IPR004344
Domain	TTL	TTLL4 TTLL1	1.51e-03	13	84	2	PF03133
Domain	Glycoside_hydrolase_SF	MGAM GUSB MGAM2	1.75e-03	53	84	3	IPR017853
Domain	Pept_C14_p20	CASP12 CASP4	1.76e-03	14	84	2	IPR001309
Domain	Caspase-like_dom	CASP12 CASP4	1.76e-03	14	84	2	IPR029030
Domain	CASPASE_P20	CASP12 CASP4	1.76e-03	14	84	2	PS50208
Domain	-	CASP12 CASP4	1.76e-03	14	84	2	3.40.50.1460
Domain	Gal_mutarotase_SF_dom	MGAM MGAM2	2.60e-03	17	84	2	IPR011013
Domain	HATPase_c	TRAP1 PDK2	2.92e-03	18	84	2	SM00387
Domain	HATPase_c	TRAP1 PDK2	3.25e-03	19	84	2	PF02518
Domain	-	TRAP1 PDK2	3.60e-03	20	84	2	3.30.565.10
Domain	HATPase_C	TRAP1 PDK2	3.97e-03	21	84	2	IPR003594
Domain	DEAD/DEAH_box_helicase_dom	DDX60 ASCC3 SNRNP200	4.35e-03	73	84	3	IPR011545
Domain	DEAD	DDX60 ASCC3 SNRNP200	4.35e-03	73	84	3	PF00270
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR5AC2 OR4A8 OR5AU1 OR5C1 OR1L6 OR5T2 OR5A1 OR5M11 OR10G9 OR10G8 OR2L13 OR6P1 OR10G7 OR10G4 OR51F1	2.24e-09	417	72	15	M4072
Pathway	KEGG_OLFACTORY_TRANSDUCTION	OR5AC2 OR5AU1 OR5C1 OR1L6 OR5T2 OR5A1 OR5M11 OR10G9 OR10G8 OR2L13 OR10G7 OR10G4 OR51F1	7.14e-08	389	72	13	M14091
Pathway	REACTOME_SENSORY_PERCEPTION	OR5AC2 OR4A8 OR5AU1 OR5C1 OR1L6 OR5T2 OR5A1 OR5M11 OR10G9 OR10G8 OR2L13 OR6P1 OR10G7 OR10G4 OR51F1	5.85e-07	636	72	15	M41834
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR10G9 OR10G8 OR2L13 OR6P1 OR10G7 OR10G4	1.45e-06	70	72	6	MM14984
Pathway	REACTOME_OTHER_SEMAPHORIN_INTERACTIONS	SEMA6D PLXNA1 PLXNA2	1.17e-04	19	72	3	M10959
Pathway	REACTOME_SENSORY_PERCEPTION	OR10G9 OR10G8 OR2L13 OR6P1 OR10G7 OR10G4	4.14e-04	190	72	6	MM15687
Pathway	REACTOME_HDMS_DEMETHYLATE_HISTONES	KDM5C ARID5B KDM5D	4.24e-04	29	72	3	MM14934
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR4A8 OR5AU1 OR5C1 OR1L6 OR5T2 OR5A1 OR5M11 OR10G9 OR10G8 OR2L13 OR6P1 OR10G7 OR10G4 OR51F1	2.20e-13	340	89	14	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR4A8 OR5AU1 OR5C1 OR1L6 OR5T2 OR5A1 OR5M11 OR10G9 OR10G8 OR2L13 OR6P1 OR10G7 OR10G4 OR51F1	2.20e-13	340	89	14	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR4A8 OR5AU1 OR5C1 OR1L6 OR5T2 OR5A1 OR5M11 OR10G9 OR10G8 OR2L13 OR6P1 OR10G7 OR10G4 OR51F1	2.48e-13	343	89	14	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR4A8 OR5AU1 OR5C1 OR1L6 OR5T2 OR5A1 OR5M11 OR10G9 OR10G8 OR2L13 OR6P1 OR10G7 OR10G4 OR51F1	2.79e-13	346	89	14	14611657
Pubmed	The human olfactory receptor gene family.	OR4A8 OR5AU1 OR5C1 OR1L6 OR5T2 OR5A1 OR5M11 OR10G9 OR10G8 OR6P1 OR10G7 OR10G4 OR51F1	1.30e-09	541	89	13	14983052
Pubmed	Transcriptome profiling reveals expression signatures of cranial neural crest cells arising from different axial levels.	ANXA2 ANXA2P2 PLXNA1 PLXNA2	1.95e-08	12	89	4	28407732
Pubmed	On and off retinal circuit assembly by divergent molecular mechanisms.	SEMA6D PLXNA1 PLXNA2	3.50e-06	12	89	3	24179230
Pubmed	A competitive hexapeptide inhibitor of annexin A2 prevents hypoxia-induced angiogenic events.	ANXA2 ANXA2P2	6.48e-06	2	89	2	21486955
Pubmed	Plexin/neuropilin complexes mediate repulsion by the axonal guidance signal semaphorin 3A.	PLXNA1 PLXNA2	6.48e-06	2	89	2	10781943
Pubmed	Caspase-12 and caspase-4 are not required for caspase-dependent endoplasmic reticulum stress-induced apoptosis.	CASP12 CASP4	6.48e-06	2	89	2	15975932
Pubmed	Lipid raft endocytosis and exosomal transport facilitate extracellular trafficking of annexin A2.	ANXA2 ANXA2P2	6.48e-06	2	89	2	21737841
Pubmed	Vascular endothelial growth factor upregulates expression of annexin A2 in vitro and in a mouse model of ischemic retinopathy.	ANXA2 ANXA2P2	6.48e-06	2	89	2	19536308
Pubmed	Annexin A2 modulates radiation-sensitive transcriptional programming and cell fate.	ANXA2 ANXA2P2	6.48e-06	2	89	2	23148505
Pubmed	Regulation of the low-dose radiation paracrine-specific anchorage-independent growth response by annexin A2.	ANXA2 ANXA2P2	6.48e-06	2	89	2	19580511
Pubmed	ANXA2 (annexin A2) is crucial to ATG7-mediated autophagy, leading to tumor aggressiveness in triple-negative breast cancer cells.	ANXA2 ANXA2P2	6.48e-06	2	89	2	38290972
Pubmed	Mouse H-Y encoding Smcy gene and its X chromosomal homolog Smcx.	KDM5C KDM5D	6.48e-06	2	89	2	10441747
Pubmed	The cDNA sequence for the protein-tyrosine kinase substrate p36 (calpactin I heavy chain) reveals a multidomain protein with internal repeats.	ANXA2 ANXA2P2	6.48e-06	2	89	2	3013423
Pubmed	Activation of Annexin A2 signaling at the blood-brain barrier in a mouse model of multiple sclerosis.	ANXA2 ANXA2P2	6.48e-06	2	89	2	35064931
Pubmed	Inefficient purifying selection: the mammalian Y chromosome in the rodent genus Mus.	KDM5C KDM5D	6.48e-06	2	89	2	16416087
Pubmed	Complex Roles of Annexin A2 in Host Blood-Brain Barrier Invasion by Cryptococcus neoformans.	ANXA2 ANXA2P2	6.48e-06	2	89	2	28130864
Pubmed	Selenomethionine promotes ANXA2 phosphorylation for proliferation and protein synthesis of myoblasts and skeletal muscle growth.	ANXA2 ANXA2P2	6.48e-06	2	89	2	36739096
Pubmed	Localization of annexin II in the paranodal regions and Schmidt-Lanterman incisures in the peripheral nervous system.	ANXA2 ANXA2P2	6.48e-06	2	89	2	17549680
Pubmed	Methionine-induced hyperhomocysteinemia reverts fibrinolytic pathway activation in a murine model of acute promyelocytic leukemia.	ANXA2 ANXA2P2	6.48e-06	2	89	2	22517898
Pubmed	Annexin A2 promotes proliferative vitreoretinopathy in response to a macrophage inflammatory signal in mice.	ANXA2 ANXA2P2	6.48e-06	2	89	2	39384746
Pubmed	Anxa2 gene silencing attenuates obesity-induced insulin resistance by suppressing the NF-κB signaling pathway.	ANXA2 ANXA2P2	6.48e-06	2	89	2	30462534
Pubmed	Annexin A2 mediates up-regulation of NF-κB, β-catenin, and stem cell in response to progastrin in mice and HEK-293 cells.	ANXA2 ANXA2P2	6.48e-06	2	89	2	20826156
Pubmed	Prohibitin/annexin 2 interaction regulates fatty acid transport in adipose tissue.	ANXA2 ANXA2P2	6.48e-06	2	89	2	27468426
Pubmed	Inhibition of the membrane repair protein annexin-A2 prevents tumor invasion and metastasis.	ANXA2 ANXA2P2	6.48e-06	2	89	2	38092984
Pubmed	Tyrosine 23 phosphorylation-dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer.	ANXA2 ANXA2P2	6.48e-06	2	89	2	21572519
Pubmed	Homocysteine inhibits neoangiogenesis in mice through blockade of annexin A2-dependent fibrinolysis.	ANXA2 ANXA2P2	6.48e-06	2	89	2	19841537
Pubmed	Mutations of histone demethylase genes encoded by X and Y chromosomes, Kdm5c and Kdm5d, lead to noncompaction cardiomyopathy in mice.	KDM5C KDM5D	6.48e-06	2	89	2	32081420
Pubmed	Hypoxia-inducible factor-1 drives annexin A2 system-mediated perivascular fibrin clearance in oxygen-induced retinopathy in mice.	ANXA2 ANXA2P2	6.48e-06	2	89	2	21788340
Pubmed	The Membrane Phospholipid Binding Protein Annexin A2 Promotes Phagocytosis and Nonlytic Exocytosis of Cryptococcus neoformans and Impacts Survival in Fungal Infection.	ANXA2 ANXA2P2	6.48e-06	2	89	2	27371724
Pubmed	Annexin A2 Modulates ROS and Impacts Inflammatory Response via IL-17 Signaling in Polymicrobial Sepsis Mice.	ANXA2 ANXA2P2	6.48e-06	2	89	2	27389701
Pubmed	Annexin A2 Deficiency Exacerbates Neuroinflammation and Long-Term Neurological Deficits after Traumatic Brain Injury in Mice.	ANXA2 ANXA2P2	6.48e-06	2	89	2	31817350
Pubmed	ANNEXIN A2 FACILITATES NEOVASCULARIZATION TO PROTECT AGAINST MYOCARDIAL INFARCTION INJURY VIA INTERACTING WITH MACROPHAGE YAP AND ENDOTHELIAL INTEGRIN Β3.	ANXA2 ANXA2P2	6.48e-06	2	89	2	37832154
Pubmed	Annexin II expressed by osteoblasts and endothelial cells regulates stem cell adhesion, homing, and engraftment following transplantation.	ANXA2 ANXA2P2	6.48e-06	2	89	2	17360942
Pubmed	Annexin A2 regulates phagocytosis of photoreceptor outer segments in the mouse retina.	ANXA2 ANXA2P2	6.48e-06	2	89	2	19587120
Pubmed	Cell-surface translocation of annexin A2 contributes to bleomycin-induced pulmonary fibrosis by mediating inflammatory response in mice.	ANXA2 ANXA2P2	6.48e-06	2	89	2	30902828
Pubmed	Analysis of mutation rates in the SMCY/SMCX genes shows that mammalian evolution is male driven.	KDM5C KDM5D	6.48e-06	2	89	2	9060413
Pubmed	Annexin A2 at the interface between F-actin and membranes enriched in phosphatidylinositol 4,5,-bisphosphate.	ANXA2 ANXA2P2	6.48e-06	2	89	2	19022301
Pubmed	Cell surface translocation of annexin A2 facilitates glutamate-induced extracellular proteolysis.	ANXA2 ANXA2P2	6.48e-06	2	89	2	24742684
Pubmed	Annexin A2 depletion exacerbates the intracerebral microhemorrhage induced by acute rickettsia and Ebola virus infections.	ANXA2 ANXA2P2	6.48e-06	2	89	2	32687500
Pubmed	Annexin A2 binds to endosomes following organelle destabilization by particulate wear debris.	ANXA2 ANXA2P2	6.48e-06	2	89	2	22453828
Pubmed	Multi-Omics Profiling Identifies Microglial Annexin A2 as a Key Mediator of NF-κB Pro-inflammatory Signaling in Ischemic Reperfusion Injury.	ANXA2 ANXA2P2	6.48e-06	2	89	2	38253182
Pubmed	Agents that bind annexin A2 suppress ocular neovascularization.	ANXA2 ANXA2P2	6.48e-06	2	89	2	20607799
Pubmed	A new role for host annexin A2 in establishing bacterial adhesion to vascular endothelial cells: lines of evidence from atomic force microscopy and an in vivo study.	ANXA2 ANXA2P2	6.48e-06	2	89	2	31253864
Pubmed	Semaphorin-6D and Plexin-A1 Act in a Non-Cell-Autonomous Manner to Position and Target Retinal Ganglion Cell Axons.	SEMA6D PLXNA1	6.48e-06	2	89	2	37344233
Pubmed	Annexin A2 is a novel cellular redox regulatory protein involved in tumorigenesis.	ANXA2 ANXA2P2	6.48e-06	2	89	2	22185818
Pubmed	Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo.	ANXA2 ANXA2P2	6.48e-06	2	89	2	19628708
Pubmed	Annexin A2 binds to the localization signal in the 3' untranslated region of c-myc mRNA.	ANXA2 ANXA2P2	6.48e-06	2	89	2	15654879
Pubmed	A mouse Y chromosome gene encoded by a region essential for spermatogenesis and expression of male-specific minor histocompatibility antigens.	KDM5C KDM5D	6.48e-06	2	89	2	7524912
Pubmed	Anti-dsDNA antibodies bind to mesangial annexin II in lupus nephritis.	ANXA2 ANXA2P2	6.48e-06	2	89	2	20847146
Pubmed	Optic chiasm presentation of Semaphorin6D in the context of Plexin-A1 and Nr-CAM promotes retinal axon midline crossing.	SEMA6D PLXNA1 PLXNA2	8.86e-06	16	89	3	22632726
Pubmed	Novel features of boundary cap cells revealed by the analysis of newly identified molecular markers.	SEMA6D ANXA2 ANXA2P2 GDAP1	1.53e-05	58	89	4	19243017
Pubmed	STARD3NL inhibits the osteogenic differentiation by inactivating the Wnt/β-catenin pathway via binding to Annexin A2 in osteoporosis.	ANXA2 ANXA2P2	1.94e-05	3	89	2	35098646
Pubmed	Structural Basis for Plexin Activation and Regulation.	PLXNA1 PLXNA2	1.94e-05	3	89	2	27397516
Pubmed	Annexin A2 promotes angiogenesis after ischemic stroke via annexin A2 receptor - AKT/ERK pathways.	ANXA2 ANXA2P2	1.94e-05	3	89	2	36367512
Pubmed	Revealing Annexin A2 and ARF-6 enrollment during Trypanosoma cruzi extracellular amastigote-host cell interaction.	ANXA2 ANXA2P2	1.94e-05	3	89	2	26416603
Pubmed	Annexin A2 depletion delays EGFR endocytic trafficking via cofilin activation and enhances EGFR signaling and metastasis formation.	ANXA2 ANXA2P2	1.94e-05	3	89	2	23792445
Pubmed	The Annexin A2-Notch regulatory loop in hepatocytes promotes liver fibrosis in NAFLD by increasing osteopontin expression.	ANXA2 ANXA2P2	1.94e-05	3	89	2	35413401
Pubmed	Identification of plexin family molecules in mice.	PLXNA1 PLXNA2	1.94e-05	3	89	2	8806646
Pubmed	Annexin A2 supports pulmonary microvascular integrity by linking vascular endothelial cadherin and protein tyrosine phosphatases.	ANXA2 ANXA2P2	1.94e-05	3	89	2	28694388
Pubmed	High Podocalyxin levels promote cell viability partially through up-regulation of Annexin A2.	ANXA2 ANXA2P2	1.94e-05	3	89	2	27470587
Pubmed	Annexin 2-CXCL12 interactions regulate metastatic cell targeting and growth in the bone marrow.	ANXA2 ANXA2P2	1.94e-05	3	89	2	25139998
Pubmed	Annexins--unique membrane binding proteins with diverse functions.	ANXA2 ANXA2P2	1.94e-05	3	89	2	15169834
Pubmed	PI3KC3 complex subunit NRBF2 is required for apoptotic cell clearance to restrict intestinal inflammation.	CCZ1B CCZ1	1.94e-05	3	89	2	32160108
Pubmed	Annexin A2 reduces PCSK9 protein levels via a translational mechanism and interacts with the M1 and M2 domains of PCSK9.	ANXA2 ANXA2P2	1.94e-05	3	89	2	24808179
Pubmed	Impaired osteoblast differentiation in annexin A2- and -A5-deficient cells.	ANXA2 ANXA2P2	1.94e-05	3	89	2	25222280
Pubmed	The Annexin a2 Promotes Development in Arthritis through Neovascularization by Amplification Hedgehog Pathway.	ANXA2 ANXA2P2	1.94e-05	3	89	2	26963384
Pubmed	Fyn-dependent phosphorylation of PlexinA1 and PlexinA2 at conserved tyrosines is essential for zebrafish eye development.	PLXNA1 PLXNA2	1.94e-05	3	89	2	29091353
Pubmed	Repulsive and attractive semaphorins cooperate to direct the navigation of cardiac neural crest cells.	PLXNA1 PLXNA2	1.94e-05	3	89	2	18625214
Pubmed	Semaphorin 6D reverse signaling controls macrophage lipid metabolism and anti-inflammatory polarization.	SEMA6D PLXNA1	1.94e-05	3	89	2	29777213
Pubmed	Identification of a mouse male-specific transplantation antigen, H-Y.	KDM5C KDM5D	1.94e-05	3	89	2	7544442
Pubmed	Macrophage surface expression of annexins I and II in the phagocytosis of apoptotic lymphocytes.	ANXA2 ANXA2P2	1.94e-05	3	89	2	15064349
Pubmed	Annexin A2 links poor myofiber repair with inflammation and adipogenic replacement of the injured muscle.	ANXA2 ANXA2P2	1.94e-05	3	89	2	28334824
Pubmed	Tenascin-c renders a proangiogenic phenotype in macrophage via annexin II.	ANXA2 ANXA2P2	1.94e-05	3	89	2	28857429
Pubmed	Fibroadipogenic progenitors are responsible for muscle loss in limb girdle muscular dystrophy 2B.	ANXA2 ANXA2P2	1.94e-05	3	89	2	31160583
Pubmed	Plexins promote Hedgehog signaling through their cytoplasmic GAP activity.	PLXNA1 PLXNA2	1.94e-05	3	89	2	36169302
Pubmed	Differential expression of plexin-A subfamily members in the mouse nervous system.	PLXNA1 PLXNA2	1.94e-05	3	89	2	11241833
Pubmed	Inhibition of ANXA2 regulated by SRF attenuates the development of severe acute pancreatitis by inhibiting the NF-κB signaling pathway.	ANXA2 ANXA2P2	1.94e-05	3	89	2	35900381
Pubmed	Annexin II interactions with the annexin II receptor enhance multiple myeloma cell adhesion and growth in the bone marrow microenvironment.	ANXA2 ANXA2P2	1.94e-05	3	89	2	22223826
Pubmed	Annexin A2 promotes phagophore assembly by enhancing Atg16L⁺ vesicle biogenesis and homotypic fusion.	ANXA2 ANXA2P2	1.94e-05	3	89	2	25597631
Pubmed	Annexin A2 regulates TRPA1-dependent nociception.	ANXA2 ANXA2P2	1.94e-05	3	89	2	25355205
Pubmed	Complete structure of the murine p36 (annexin II) gene. Identification of mRNAs for both the murine and the human gene with alternatively spliced 5' noncoding exons.	ANXA2 ANXA2P2	1.94e-05	3	89	2	8634333
Pubmed	RNASEH1-AS1 induced by H3K27ac stabilizes ANXA2 mRNA to promote the progression of colorectal cancer through recruiting BUD13.	ANXA2 ANXA2P2	1.94e-05	3	89	2	38053379
Pubmed	Chromosomal localization of the human genes for lipocortin I and lipocortin II.	ANXA2 ANXA2P2	1.94e-05	3	89	2	2969496
Pubmed	Upregulation of HDAC9 in hippocampal neurons mediates depression-like behaviours by inhibiting ANXA2 degradation.	ANXA2 ANXA2P2	1.94e-05	3	89	2	37690046
Pubmed	Annexin-2 is a regulator of stromal cell-derived factor-1/CXCL12 function in the hematopoietic stem cell endosteal niche.	ANXA2 ANXA2P2	1.94e-05	3	89	2	21108988
Pubmed	The Tick Protein Sialostatin L2 Binds to Annexin A2 and Inhibits NLRC4-Mediated Inflammasome Activation.	ANXA2 ANXA2P2	1.94e-05	3	89	2	27045038
Pubmed	Accumulation of annexin A2 and S100A10 prevents apoptosis of apically delaminated, transformed epithelial cells.	ANXA2 ANXA2P2	1.94e-05	3	89	2	37844241
Pubmed	Hepatic Overexpression of Annexin A1 and A2 in Thioacetamide-Primed Mice Protects Them Against Acetaminophen-Induced Liver Failure and Death.	ANXA2 ANXA2P2	1.94e-05	3	89	2	27451051
Pubmed	Caspase-12 ablation preserves muscle function in the mdx mouse.	CASP12 CASP4	1.94e-05	3	89	2	24879640
Pubmed	FOXQ1 promotes the osteogenic differentiation of bone mesenchymal stem cells via Wnt/β-catenin signaling by binding with ANXA2.	ANXA2 ANXA2P2	1.94e-05	3	89	2	32943107
Pubmed	Prostaglandin-endoperoxide synthase-2 deletion affects the natural trafficking of Annexin A2 in monocytes and favours venous thrombosis in mice.	ANXA2 ANXA2P2	1.94e-05	3	89	2	28536720
Pubmed	Annexin II is a thiazolidinedione-responsive gene involved in insulin-induced glucose transporter isoform 4 translocation in 3T3-L1 adipocytes.	ANXA2 ANXA2P2	1.94e-05	3	89	2	14726447
Pubmed	Mitochondrially mediated integrin αIIbβ3 protein inactivation limits thrombus growth.	ANXA2 ANXA2P2	1.94e-05	3	89	2	24014035
Pubmed	Annexin A2 contributes to lung injury and fibrosis by augmenting factor Xa fibrogenic activity.	ANXA2 ANXA2P2	1.94e-05	3	89	2	28283478
Pubmed	Annexin A2 tetramer activates human and murine macrophages through TLR4.	ANXA2 ANXA2P2	3.87e-05	4	89	2	19965653
Pubmed	A new cis-acting motif is required for the axonal SMN-dependent Anxa2 mRNA localization.	ANXA2 ANXA2P2	3.87e-05	4	89	2	28258160
Cytoband	Ensembl 112 genes in cytogenetic band chr11q24	OR10G9 OR10G8 OR10G7 OR10G4	5.38e-04	191	89	4	chr11q24
Cytoband	Ensembl 112 genes in cytogenetic band chr11q22	CASP12 POGLUT3 CASP4	1.21e-03	107	89	3	chr11q22
Cytoband	6q15	DOP1A PM20D2	1.67e-03	31	89	2	6q15
Cytoband	11q24.1	OR10G9 OR10G4	2.37e-03	37	89	2	11q24.1
Cytoband	9q33.2	OR5C1 OR1L6	2.63e-03	39	89	2	9q33.2
Cytoband	11q22.3	CASP12 POGLUT3	3.33e-03	44	89	2	11q22.3
Cytoband	7p22.1	CCZ1B CCZ1	3.80e-03	47	89	2	7p22.1
Cytoband	11q12.1	OR5T2 OR5A1 OR5M11	3.86e-03	161	89	3	11q12.1
Cytoband	7q34	MGAM DENND11 MGAM2	4.27e-03	167	89	3	7q34
GeneFamily	Olfactory receptors, family 5	OR5AC2 OR5AU1 OR5C1 OR5T2 OR5A1 OR5M11	2.29e-06	112	62	6	152
GeneFamily	AT-rich interaction domain containing	KDM5C ARID5B KDM5D	1.70e-05	15	62	3	418
GeneFamily	Olfactory receptors, family 10	OR10G9 OR10G8 OR10G7 OR10G4	7.70e-05	66	62	4	157
GeneFamily	Plexins	PLXNA1 PLXNA2	4.10e-04	9	62	2	683
GeneFamily	X-linked mental retardation\|RNA helicases	ASCC3 SNRNP200	6.24e-04	11	62	2	1168
GeneFamily	Caspases\|Caspase recruitment domain containing	CASP12 CASP4	8.81e-04	13	62	2	468
GeneFamily	Tubulin tyrosine ligase family	TTLL4 TTLL1	1.03e-03	14	62	2	779
GeneFamily	Beta 4-glycosyltransferases	B4GALNT1 CHSY1	1.52e-03	17	62	2	425
GeneFamily	PHD finger proteins\|Lysine demethylases	KDM5C KDM5D	3.04e-03	24	62	2	485
GeneFamily	WD repeat domain containing\|Caspase recruitment domain containing\|Apoptosome	CASP12 CASP4	4.73e-03	30	62	2	959
Drug	BuPdGTP	POLE LSS GPR148 SMG6	7.35e-06	34	84	4	CID000123713
Drug	i14:0	MPO GUSB	1.35e-05	2	84	2	CID000520298
Drug	BW755C	MPO PTCHD3 GUSB PI4KA COX11	2.44e-05	93	84	5	CID000047795
Drug	hygromycin A	SLC5A5 MGAM INTU GUSB KDM5D	3.47e-05	100	84	5	CID006433481
Drug	3'-azido-2-chloro-2',3'-dideoxyadenosine	GPR148 SMG6	4.03e-05	3	84	2	CID000474898
Drug	StddUTP	GPR148 SMG6	4.03e-05	3	84	2	CID005274129
Drug	hTERT I540	GPR148 SMG6	4.03e-05	3	84	2	CID000403992
Drug	9-(benzotriazol-1-yl)acridine	GPR148 SMG6	4.03e-05	3	84	2	CID011312489
Drug	5-ClAU	POLE GPR148 SMG6	4.50e-05	19	84	3	CID000126441
Drug	naphthol AS	MPO MGAM GUSB	4.50e-05	19	84	3	CID000066719
Drug	poly(vA	POLE GPR148 SMG6	4.50e-05	19	84	3	CID000429118
Drug	dercitin	POLE GPR148 SMG6	4.50e-05	19	84	3	CID000130774
Drug	aucubigenin	POLE GPR148 SMG6	4.50e-05	19	84	3	CID000163040
Drug	OXT-ATP	POLE GPR148 SMG6	5.28e-05	20	84	3	CID000454146
Drug	AC1MHT6K	POLE GPR148 SMG6	5.28e-05	20	84	3	CID003010960
Drug	azide	MPO MGAM GUSB POLE WDR81 COX11	5.48e-05	180	84	6	CID000033558
Drug	AC1L3V16	POLE GPR148 SMG6	6.14e-05	21	84	3	CID000122664
Drug	parazoanthoxanthin A	POLE GPR148 SMG6	6.14e-05	21	84	3	CID000323259
Drug	potassium carbonate	MGAM GUSB PLXNA2	6.14e-05	21	84	3	CID000011430
Drug	petasiphenol	POLE GPR148 SMG6	7.09e-05	22	84	3	CID006438779
Drug	BVdUTP	POLE GPR148 SMG6	7.09e-05	22	84	3	CID006438404
Drug	U-78036	POLE GPR148 SMG6	7.09e-05	22	84	3	CID000072244
Drug	AC1LA211	POLE GPR148 SMG6	7.09e-05	22	84	3	CID000480107
Drug	3'-deoxythymidine	SLC29A3 POLE GPR148 SMG6	7.66e-05	61	84	4	CID000005280
Drug	AC1L59FT	INTU GUSB	8.03e-05	4	84	2	CID000172847
Drug	2-isopropylnaphthalene	GUSB KDM5D	8.03e-05	4	84	2	CID000016238
Drug	DNC000045	GPR148 SMG6	8.03e-05	4	84	2	CID010378848
Drug	MST-312	GPR148 SMG6	8.03e-05	4	84	2	CID010385095
Drug	PHA-00851261E [724719-49-7]; Up 200; 1uM; MCF7; HT_HG-U133A	TTLL4 GDAP1 LSS TTLL1 SLC1A3 SMG6	8.06e-05	193	84	6	3857_UP
Drug	BrVarafUTP	POLE GPR148 SMG6	9.27e-05	24	84	3	CID005273539
Drug	p-azoxyanisole	PMPCA POLE GPR148 SMG6	1.11e-04	67	84	4	CID000015277
Drug	AC1L1CVV	POLE GPR148 SMG6	1.18e-04	26	84	3	CID000027281
Drug	araTTP	POLE GPR148 SMG6	1.33e-04	27	84	3	CID000072188
Drug	AC1L9I2M	GPR148 SMG6	1.34e-04	5	84	2	CID000399187
Drug	EDTA-chromium	MPO MGAM	1.34e-04	5	84	2	CID000028282
Drug	quindoline	GPR148 SMG6	1.34e-04	5	84	2	CID000098912
Drug	KC-764	MPO GUSB	1.34e-04	5	84	2	CID000146826
Drug	hydroxycarbonate	MGAM GUSB	1.34e-04	5	84	2	CID000181880
Drug	R)-PCV-TP	POLE GPR148 SMG6	1.48e-04	28	84	3	CID000506602
Disease	smoking behavior	SEMA6D ARID5B XKR6 ASCC3 HS6ST3 PLXNA2 SMG6	3.39e-05	341	78	7	EFO_0004318
Disease	syndromic X-linked intellectual disability Claes-Jensen type (implicated_via_orthology)	KDM5C KDM5D	4.12e-05	4	78	2	DOID:0060809 (implicated_via_orthology)
Disease	risk-taking behaviour	FZD7 CASP12 SEMA6D ARID5B NFASC XKR6 ASCC3 HS6ST3 PLXNA2	1.85e-04	764	78	9	EFO_0008579
Disease	neutrophil count, eosinophil count	MPO TRAP1 PMPCA CHSY1 XKR6	2.57e-04	213	78	5	EFO_0004833, EFO_0004842
Disease	attention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement	FZD7 SEMA6D ARID5B NFASC XKR6 ASCC3 HS6ST3 PLXNA2 SMG6	2.62e-04	801	78	9	EFO_0003888, EFO_0007052, MONDO_0002491
Disease	neutrophil count, basophil count	MPO TRAP1 PMPCA CHSY1 XKR6	3.24e-04	224	78	5	EFO_0004833, EFO_0005090
Disease	granulocyte count	MPO TRAP1 PMPCA CHSY1 XKR6	5.75e-04	254	78	5	EFO_0007987
Disease	renal cell carcinoma (biomarker_via_orthology)	ANXA2 ANXA2P2	6.15e-04	14	78	2	DOID:4450 (biomarker_via_orthology)
Disease	Hermansky-Pudlak syndrome (implicated_via_orthology)	CCZ1B CCZ1	6.15e-04	14	78	2	DOID:3753 (implicated_via_orthology)
Disease	syndromic intellectual disability (implicated_via_orthology)	KDM5C KDM5D	8.08e-04	16	78	2	DOID:0050888 (implicated_via_orthology)
Disease	smoking status measurement	FZD7 TRAP1 SEMA6D ARID5B OR5A1 XKR6 ASCC3 HS6ST3 PLXNA2 SMG6	9.43e-04	1160	78	10	EFO_0006527
Disease	sensory perception of bitter taste	MGAM DENND11	2.15e-03	26	78	2	GO_0050913
Disease	hyperthyroidism (biomarker_via_orthology)	ANXA2 ANXA2P2	2.49e-03	28	78	2	DOID:7998 (biomarker_via_orthology)
Disease	chronic obstructive pulmonary disease (biomarker_via_orthology)	MPO CASP12	2.49e-03	28	78	2	DOID:3083 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
VYYYMRSLAASNPIL	SMG6	786	Q86US8
RYLMDYLNPLILSYV	CFAP54	1451	Q96N23
FTEIDRMPQLLAYYY	COG7	211	P83436
YARYRYPGSLDESQM	B4GALNT1	501	Q00973
TIERLSMTRYFYLFP	CASP4	361	P49662
PLQSPREYLYRYRTM	ARSI	241	Q5FYB1
LISLCLYYMRSHYPT	DOP1A	1456	Q5JWR5
RYKSYSPYDMLESIR	ANXA2	231	P07355
RYKSYSPYDMLESIR	ANXA2P2	231	A6NMY6
IERLSMTRYFYLFPG	CASP12	326	Q6UXS9
AMAYDRYVAIYDPLR	OR5M11	116	Q96RB7
VMSYDRYLAISYPLR	OR10G7	116	Q8NGN6
VMSYDRYLAISYPLR	OR10G4	116	Q8NGN3
RYLAISYPLRYTSMM	OR10G4	121	Q8NGN3
RSYFRAYMILLPFSE	GPR39	316	O43194
RYTLLPYLYTLMHKA	MGAM2	1566	Q2M2H8
LGVLYSMYKDYIRPR	HIGD1C	76	A8MV81
TRYTLLPYLYTLMQK	MGAM	1611	O43451
YLRYRYTLDELPTML	KDM5D	736	Q9BY66
DVLCLYAYLLPSMYR	DDX60	181	Q8IY21
FLDYRTYAMRVLFPG	PLXNA1	1321	Q9UIW2
GIPYLDYRTYAMRVL	PLXNA2	1311	O75051
YYDYISPRFMTILRR	OGDHL	951	Q9ULD0
YIHMLSLSLVYRYGR	OR51F1	261	A6NGY5
MAYDRYAAISSPLLY	OR5A1	121	Q8NGJ0
AMRKYLPTYRSYNDS	MPO	471	P05164
MYYPRVQHYRELLDS	GDAP1	116	Q8TB36
VYLPMSYCYAVRLSA	LSS	236	P48449
TYLLSVYRLEYMRVL	PI4KA	891	P42356
SGTLAAYYRLMRPYL	MSLNL	486	Q96KJ4
RVLPRSNMVYNLYEY	POLE	1386	Q07864
RYLAISYPLRYTSMM	OR10G8	121	Q8NGN5
YGTLIFMYLRPSSSY	OR5C1	256	Q8NGR4
RNFYYITMLRDPVSR	HS6ST3	236	Q8IZP7
PLRKIERLFSYMYST	PDK2	296	Q15119
LSYDYRPSYRMSVIA	DCHS2	1361	Q6V1P9
LSEDYYDMRRLYTIL	INTU	501	Q9ULD6
SLYYGTLIFMYVRPA	OR5AC2	251	Q9NZP5
LTDLYPGMTYTLRVY	NFASC	1171	O94856
LSYMLSGYRPYLSSE	OSGIN2	31	Q9Y236
YYSSTLFTYARPRAM	OR6P1	251	Q8NGX9
TVLTYLVDMRRFSYP	FZD7	271	O75084
TYSFYIRRLPMFYTI	CHRNA6	231	Q15825
RLSYAEMAEDYPRYP	CLCN6	771	P51797
MLGASYAAVPLYRLY	COX11	106	Q9Y6N1
ILSPSYTLLYRYMHF	DENND11	156	A4D1U4
ATTYYLADRRYDMLP	DIS3L	526	Q8TF46
FTLRPYRMSYREVKY	SLC1A3	66	P43003
YLMHERPAYLYSLEV	GUSB	291	P08236
LPRAMLTYLYLLRYR	GPR148	311	Q8TDV2
MRILYKYLTTSLFPR	CCZ1	241	P86791
MRILYKYLTTSLFPR	CCZ1B	241	P86790
YRQPYMTSISYRPAC	KRTAP16-1	411	A8MUX0
MYYTSPLYRDELVKG	DDHD1	491	Q8NEL9
YLPDLMYLDYRRIDD	DRC3	181	Q9H069
SDRYYTALYRKMLDP	CEBPZ	541	Q03701
AMRLLYYLKTEDPEY	PTCHD3	321	Q3KNS1
VMSYDRYLAISYPLR	OR10G9	116	Q8NGN4
RYLAISYPLRYTSMM	OR10G9	121	Q8NGN4
SIIYVYFRPLSMYSV	OR1L6	291	Q8NGR2
YFRPLSMYSVVRDRV	OR1L6	296	Q8NGR2
RYLAICHSLYYPIRM	OR2L13	121	Q8N349
MAYDRYVATCKPLRY	OR4A8	116	P0C604
YLRNYYTPDRMVLAG	PMPCA	241	Q10713
LSRLEYARYYMRPVL	SLC29A3	251	Q9BZD2
RMNSYPYLADRHYSR	RBM7	201	Q9Y580
RCRYYSNLRLPLMYS	SEZ6L	981	Q9BYH1
TLFMYLRPRSSYSLT	OR5AU1	306	Q8NGC0
LYLYRCITMYVTTLP	SGMS2	166	Q8NHU3
AMAYDRYVAIYNPLL	OR5T2	156	Q8NGG2
RYVAIYNPLLYSVSM	OR5T2	161	Q8NGG2
PSYSELIYYFRAPSM	PM20D2	266	Q8IYS1
KYPRREYYFAITMER	SUCLA2	161	Q9P2R7
VIVLSYPQYCRYRSM	ARID5B	176	Q14865
YLYVRMRANPLAYGI	ASCC3	921	Q8N3C0
YRRVNPMYGAEYILD	CHSY1	436	Q86X52
TVAAYRYPYLMLGDS	POGLUT3	376	Q7Z4H8
RASAYEALEKYPMAY	TOMM34	91	Q15785
GRTRYRMFAYYTIVL	XKR6	436	Q5GH73
YSRKGPELLMYTYSS	TRAV12-3	61	A0A0B4J271
RVLRMLRYPRYIYTT	POLR3C	81	Q9BUI4
RSEMCLSYLLYYPRI	MOXD1	461	Q6UVY6
MPVFYRLGLTSTYEY	SLC5A5	106	Q92911
DRYYRLAPMRLYTLS	TMEM181	136	Q9P2C4
LIDPLYLMAQVRYYS	TTC21A	501	Q8NDW8
GYAYLYIRMLRSPTL	SNRNP200	921	O75643
YASRMRAGTRNIYYL	TRAP1	486	Q12931
SSSILYRYPFERLKM	SNTB2	476	Q13425
FNPMCRYYRLSTLEY	SEMA6D	141	Q8NFY4
YVTSLLKMYVRRPYS	TTLL4	871	Q14679
SDITYYVYKARRTPR	WDR81	446	Q562E7
VLVSTYRPLRCYMYK	TTLL1	201	O95922
YLRYRYTLDELPAML	KDM5C	746	P41229