Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA-DNA hybrid ribonuclease activity

ERVK-6 ERVK-7 ERVK-10 ERVK-11

6.55e-07111364GO:0004523
GeneOntologyMolecularFunctionRNA-directed DNA polymerase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-11

1.95e-06141364GO:0003964
GeneOntologyMolecularFunctionDNA polymerase activity

ERVK-6 ERVK-7 ERVK-10 REV3L ERVK-11

5.70e-06381365GO:0034061
GeneOntologyMolecularFunctionRNA stem-loop binding

ERVK-6 ERVK-7 ERVK-10 ERVK-11

1.13e-05211364GO:0035613
GeneOntologyMolecularFunctionnucleotidyltransferase activity

ERVK-6 CTU2 ERVK-7 ERVK-10 REV3L PARP14 ERVK-11

8.29e-051521367GO:0016779
GeneOntologyMolecularFunctionRNA endonuclease activity, producing 5'-phosphomonoesters

ERVK-6 ERVK-7 ERVK-10 ERVK-11

1.14e-04371364GO:0016891
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-25

1.14e-04371364GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-25

1.27e-04381364GO:0070001
GeneOntologyMolecularFunctionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

ERVK-6 ERVK-7 ERVK-10 ERVK-11

2.69e-04461364GO:0016893
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

ERVK-6 ERVK-7 ERVK-10 REV3L ARID1A MLH3 SHPRH ERVK-11

4.38e-042621368GO:0140097
GeneOntologyMolecularFunctionalkaline phosphatase activity

CILP CILP2

6.78e-0461362GO:0004035
GeneOntologyMolecularFunctionsphingosine-1-phosphate phosphatase activity

SGPP1 PLPP2

9.46e-0471362GO:0042392
GeneOntologyMolecularFunctionmicrotubule motor activity

KIF18A DNAH10 KIF26A KIF11

1.33e-03701364GO:0003777
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

ERVK-6 ERVK-7 ERVK-10 REV3L ARID1A DUS1L MLH3 SHPRH TRMT13 ERVK-11 QARS1 TDRD12

1.54e-0364513612GO:0140640
GeneOntologyMolecularFunctiondinucleotide phosphatase activity

CILP CILP2

1.61e-0391362GO:0004551
GeneOntologyMolecularFunctionG protein-coupled glutamate receptor activity

GRM1 GRM6

1.61e-0391362GO:0098988
GeneOntologyMolecularFunctionadenylate cyclase inhibiting G protein-coupled glutamate receptor activity

GRM1 GRM6

1.61e-0391362GO:0001640
GeneOntologyMolecularFunctionactin binding

KIF18A SPATA31A3 SPATA31A7 FERMT1 SPATA31A5 PDLIM5 SPATA31A1 EGFR XIRP2 CTNNA3

1.66e-0347913610GO:0003779
GeneOntologyBiologicalProcessDNA synthesis involved in DNA repair

ERVK-6 ERVK-7 ERVK-10 REV3L SIRT1 ERVK-11

7.83e-07481386GO:0000731
GeneOntologyBiologicalProcessDNA integration

ERVK-6 ERVK-7 ERVK-10 ERVK-11

1.31e-06131384GO:0015074
DomainDUF4599

SPATA31A3 SPATA31A7 SPATA31A5

6.92e-05121303PF15371
DomainDUF4599

SPATA31A3 SPATA31A7 SPATA31A5

6.92e-05121303IPR027970
DomainCarboxyPept-like_regulatory

CILP CILP2 TENM4

2.09e-04171303IPR008969
DomainHEAT

TNPO1 NCAPD3 TNPO2 HTT

3.44e-04481304PF02985
DomainFerI

MYOF OTOF

4.74e-0451302SM01202
DomainFerB

MYOF OTOF

4.74e-0451302SM01201
DomainFerlin_B-domain

MYOF OTOF

4.74e-0451302IPR012561
DomainFerlin_C

MYOF OTOF

4.74e-0451302PF16165
DomainFerlin_C

MYOF OTOF

4.74e-0451302IPR032362
DomainFerIin_dom

MYOF OTOF

4.74e-0451302IPR012968
DomainFerI

MYOF OTOF

4.74e-0451302PF08151
DomainFerB

MYOF OTOF

4.74e-0451302PF08150
DomainWxxW_domain

CILP CILP2

7.08e-0461302IPR025155
DomainMucin2_WxxW

CILP CILP2

7.08e-0461302PF13330
DomainHEAT

TNPO1 NCAPD3 TNPO2 HTT

7.11e-04581304IPR000357
DomainTSP_1

CILP THSD7B CILP2 SPON1

9.72e-04631304PF00090
DomainTSP1

CILP THSD7B CILP2 SPON1

1.09e-03651304SM00209
DomainTSP1_rpt

CILP THSD7B CILP2 SPON1

1.09e-03651304IPR000884
DomainTSP1

CILP THSD7B CILP2 SPON1

1.09e-03651304PS50092
DomainGPCR_3_mtglu_rcpt

GRM1 GRM6

1.31e-0381302IPR000162
DomainHEAT_REPEAT

TNPO1 NCAPD3 TNPO2 HTT

1.44e-03701304PS50077
DomaincNMP

RAPGEF6 KCNH3 KCNH6

1.68e-03341303SM00100
DomaincNMP_binding

RAPGEF6 KCNH3 KCNH6

1.68e-03341303PF00027
DomaincNMP-bd_dom

RAPGEF6 KCNH3 KCNH6

1.83e-03351303IPR000595
DomainATPase_P-typ_cyto_domN

ATP8B3 ATP2B3 ATP4A

1.83e-03351303IPR023299
DomainCNMP_BINDING_3

RAPGEF6 KCNH3 KCNH6

1.83e-03351303PS50042
DomainATPase_P-typ_P_site

ATP8B3 ATP2B3 ATP4A

1.99e-03361303IPR018303
DomainP_typ_ATPase

ATP8B3 ATP2B3 ATP4A

1.99e-03361303IPR001757
DomainATPASE_E1_E2

ATP8B3 ATP2B3 ATP4A

1.99e-03361303PS00154
DomainPAS_9

KCNH3 KCNH6

2.09e-03101302PF13426
DomainHydrolase_3

ATP8B3 ATP2B3

2.09e-03101302PF08282
DomainATPase_P-typ_transduc_dom_A

ATP8B3 ATP2B3 ATP4A

2.15e-03371303IPR008250
DomainE1-E2_ATPase

ATP8B3 ATP2B3 ATP4A

2.15e-03371303PF00122
DomainC2

ABR PCLO MYOF OTOF SYT5

2.24e-031311305PF00168
DomaincNMP-bd-like

RAPGEF6 KCNH3 KCNH6

2.33e-03381303IPR018490
DomainPKD_channel

PKD1L1 PKD1L3

2.54e-03111302PF08016
DomainPKD1_2_channel

PKD1L1 PKD1L3

2.54e-03111302IPR013122
DomainC2

ABR PCLO MYOF OTOF SYT5

2.72e-031371305SM00239
DomainC-type_lectin-like

MRC1 PKD1L3 PRG3 CLEC16A

3.06e-03861304IPR001304
DomainC2

ABR PCLO MYOF OTOF SYT5

3.17e-031421305PS50004
DomainRossmann-like_a/b/a_fold

CTU2 ASS1 QARS1

3.32e-03431303IPR014729
Domain-

CTU2 ASS1 QARS1

3.32e-034313033.40.50.620
DomainKinesin-like_fam

KIF18A KIF26A KIF11

3.32e-03431303IPR027640
Domain-

KIF18A KIF26A KIF11

3.54e-034413033.40.850.10
DomainKinesin

KIF18A KIF26A KIF11

3.54e-03441303PF00225
DomainKISc

KIF18A KIF26A KIF11

3.54e-03441303SM00129
DomainKINESIN_MOTOR_1

KIF18A KIF26A KIF11

3.54e-03441303PS00411
DomainKinesin_motor_dom

KIF18A KIF26A KIF11

3.54e-03441303IPR001752
DomainKINESIN_MOTOR_2

KIF18A KIF26A KIF11

3.54e-03441303PS50067
DomainNCD3G

GRM1 GRM6

3.57e-03131302PF07562
DomainGPCR_3_9-Cys_dom

GRM1 GRM6

3.57e-03131302IPR011500
Domain-

MRC1 IGF2R

3.57e-031313022.10.10.10
Domain-

ABR PCLO MYOF OTOF SYT5

3.78e-0314813052.60.40.150
DomainFN_type2_col-bd

MRC1 IGF2R

4.14e-03141302IPR000562
DomainFN2_2

MRC1 IGF2R

4.14e-03141302PS51092
DomainIMPORTIN_B_NT

TNPO1 TNPO2

4.14e-03141302PS50166
DomainFN2_1

MRC1 IGF2R

4.14e-03141302PS00023
DomainK_chnl_volt-dep_EAG/ELK/ERG

KCNH3 KCNH6

4.14e-03141302IPR003938
DomainTUDOR

TDRD6 TDRD12

4.14e-03141302PF00567
Domainfn2

MRC1 IGF2R

4.14e-03141302PF00040
DomainGPCR_3_CS

GRM1 GRM6

4.14e-03141302IPR017979
DomainFN2

MRC1 IGF2R

4.14e-03141302SM00059
Domain-

RAPGEF6 KCNH3 KCNH6

4.53e-034813032.60.120.10
Domain-

TNPO1 NCAPD3 INTS7 TNPO2 ARID1A HTT

4.63e-0322213061.25.10.10
DomainIBN_N

TNPO1 TNPO2

4.76e-03151302PF03810
DomainRmlC-like_jellyroll

RAPGEF6 KCNH3 KCNH6

5.38e-03511303IPR014710
DomainIBN_N

TNPO1 TNPO2

5.41e-03161302SM00913
DomainATPase_P-typ_TM_dom

ATP2B3 ATP4A

5.41e-03161302IPR023298
Domain-

ATP2B3 ATP4A

5.41e-031613021.20.1110.10
DomainC2_dom

ABR PCLO MYOF OTOF SYT5

5.83e-031641305IPR000008
DomainATPase_P-typ_cation-transptr_C

ATP2B3 ATP4A

6.11e-03171302IPR006068
DomainCation_ATPase_C

ATP2B3 ATP4A

6.11e-03171302PF00689
DomainImportin-beta_N

TNPO1 TNPO2

6.11e-03171302IPR001494
DomainLH2

PKD1L1 PKD1L3

6.84e-03181302SM00308
DomainCation_ATPase_N

ATP2B3 ATP4A

6.84e-03181302PF00690
Domain-

SGPP1 PLPP2

6.84e-031813021.20.144.10
DomainCation_ATPase_N

ATP2B3 ATP4A

6.84e-03181302SM00831
DomainacidPPc

SGPP1 PLPP2

6.84e-03181302SM00014
Pubmed

The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.

SPATA31A3 SPATA31A7 SPATA31A5 SPATA31A1

4.20e-096144420850414
Pubmed

Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.

SPATA31A3 SPATA31A7 SPATA31A5 SPATA31A1

4.20e-096144425930072
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

ATP8B3 DNAH10 MTHFD2 GRK6 KDM3B DNM1L RNF40 SEMA3G ARID1A GFPT1 KCNH3 KCNH6 EGFR FUT4 ATP4A WNK3 KIF11

1.08e-087301441734857952
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MTA2 RAPGEF6 ABR KIF26A GRK6 KDM3B CBLC RNF40 REV3L ARID1A DUS1L KCNH3 MYOF IGF2R WIZ TULP4 LRP3 SNAPC4 HTT

1.69e-0711051441935748872
Pubmed

Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.

ERVK-6 ERVK-7 ERVK-10

2.77e-074144310469592
Pubmed

Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.

SPATA31A3 SPATA31A7 SPATA31A5 SPATA31A1

2.81e-0624144432212159
Pubmed

Ferlin Overview: From Membrane to Cancer Biology.

MYOF OTOF

1.70e-052144231443490
Pubmed

Engagement of the mannose receptor by tumoral mucins activates an immune suppressive phenotype in human tumor-associated macrophages.

MRC1 MUC16

1.70e-052144221331365
Pubmed

Piccolo mediates EGFR signaling and acts as a prognostic biomarker in esophageal squamous cell carcinoma.

PCLO EGFR

1.70e-052144228263981
Pubmed

Autocrine ligands of the epithelial growth factor receptor mediate inflammatory responses to diesel exhaust particles.

EGFR CXCL8

1.70e-052144224555532
Pubmed

Mutant huntingtin regulates EGF receptor fate in non-neuronal cells lacking wild-type protein.

EGFR HTT

1.70e-052144222974559
Pubmed

Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins.

TNPO1 TNPO2

1.70e-05214429298975
Pubmed

Scratch wound-induced CXCL8 upregulation is EGFR-dependent in keratinocytes.

EGFR CXCL8

1.70e-052144232690371
Pubmed

Transportin-1 and Transportin-2: protein nuclear import and beyond.

TNPO1 TNPO2

1.70e-052144224780099
Pubmed

Inhibition of Drp1 hyperactivation reduces neuropathology and behavioral deficits in zQ175 knock-in mouse model of Huntington's disease.

DNM1L HTT

1.70e-052144230449600
Pubmed

Environmental tobacco smoke increases autophagic effects but decreases longevity associated with Sirt-1 protein expression in young C57BL mice hearts.

SIRT1 IGF2R

1.70e-052144227167200
Pubmed

IL8 and EDEM3 gene expression ratio indicates peripheral blood mononuclear cell (PBMC) quality.

EDEM3 CXCL8

1.70e-052144230496732
Pubmed

Kindlin-1 Regulates Epidermal Growth Factor Receptor Signaling.

FERMT1 EGFR

1.70e-052144230248333
Pubmed

Mutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease.

DNM1L HTT

1.70e-052144221997870
Pubmed

Enteroaggregative Escherichia coli induced activation of epidermal growth factor receptor contributes to IL-8 secretion by cultured human intestinal epithelial cells.

EGFR CXCL8

1.70e-052144237290638
Pubmed

Ratio of Apolipoprotein A-II/B Improves Risk Prediction of Postoperative Survival After Carotid Endarterectomy.

APOA2 APOB

1.70e-052144225953375
Pubmed

Elevated Type 1 Metabotropic Glutamate Receptor Availability in a Mouse Model of Huntington's Disease: a Longitudinal PET Study.

GRM1 HTT

1.70e-052144231912442
Pubmed

Cartilage intermediate layer protein 2 (CILP-2) is expressed in articular and meniscal cartilage and down-regulated in experimental osteoarthritis.

CILP CILP2

1.70e-052144221880736
Pubmed

Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity.

DNM1L HTT

1.70e-052144221336284
Pubmed

Upregulation of E3 Ubiquitin Ligase CBLC Enhances EGFR Dysregulation and Signaling in Lung Adenocarcinoma.

CBLC EGFR

1.70e-052144229945960
Pubmed

BANK negatively regulates Akt activation and subsequent B cell responses.

CD40 BANK1

1.70e-052144216546095
Pubmed

Mycoplasma pneumoniae induces interleukin-8 production via the epidermal growth factor receptor pathway.

EGFR CXCL8

1.70e-052144221831204
Pubmed

EGF-induced centrosome separation promotes mitotic progression and cell survival.

EGFR KIF11

1.70e-052144223643362
Pubmed

Metabolism of apolipoprotein A-II containing triglyceride rich ApoB lipoproteins in humans.

APOA2 APOB

1.70e-052144226071654
Pubmed

SIRT1 regulates TNF-α-induced expression of CD40 in 3T3-L1 adipocytes via NF-κB pathway.

SIRT1 CD40

1.70e-052144222717288
Pubmed

Helicobacter pylori-stimulated interleukin-8 (IL-8) promotes cell proliferation through transactivation of epidermal growth factor receptor (EGFR) by disintegrin and metalloproteinase (ADAM) activation.

EGFR CXCL8

1.70e-052144216240219
Pubmed

The cancer antigen CA125 represents a novel counter receptor for galectin-1.

MUC16 LGALS1

1.70e-052144212615972
Pubmed

Phosphorylation of the epidermal growth factor receptor (EGFR) is essential for interleukin-8 release from intestinal epithelial cells in response to challenge with Escherichia coli O157 : H7 flagellin.

EGFR CXCL8

1.70e-052144221546588
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

TNPO1 CTU2 KDM3B GATM DNM1L APOB GFPT1 LGALS1 EDEM3 MYOF IGF2R PLPP2 EGFR ASS1 QARS1 CLUH KIF11

2.81e-0512971441733545068
Pubmed

ATRX proximal protein associations boast roles beyond histone deposition.

TNPO1 MTA2 TNPO2 SIRT1 WIZ

3.96e-0591144534780483
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

KIF18A NCAPD3 CBX4 REV3L SIRT1 MLH3 WIZ

4.12e-05222144737071664
Pubmed

A revised nomenclature for transcribed human endogenous retroviral loci.

ERVK-6 ERVK-7 ERVK-10 ERVK-25 ERVK-11

4.63e-0594144521542922
Pubmed

Genetic heterogeneity of plasma lipoproteins in the mouse: control of low density lipoprotein particle sizes by genetic factors.

APOA2 APOB

5.09e-05314421971301
Pubmed

Neuregulin 1/ErbB signalling modulates hippocampal mGluRI-dependent LTD and object recognition memory.

GRM1 EGFR

5.09e-053144229427771
Pubmed

Identification of a karyopherin β1/β2 proline-tyrosine nuclear localization signal in huntingtin protein.

TNPO1 HTT

5.09e-053144223012356
Pubmed

Loss of function Cbl-c mutations in solid tumors.

CBLC EGFR

5.09e-053144231260484
Pubmed

FerA is a Membrane-Associating Four-Helix Bundle Domain in the Ferlin Family of Membrane-Fusion Proteins.

MYOF OTOF

5.09e-053144230026467
Pubmed

SIRT1 Activation Attenuates Bone Cancer Pain by Inhibiting mGluR1/5.

GRM1 SIRT1

5.09e-053144231270711
Pubmed

TNPO1-mediated nuclear import of ARID1B promotes tumor growth in ARID1A-deficient gynecologic cancer.

TNPO1 ARID1A

5.09e-053144234044070
Pubmed

IL-8-induced O-GlcNAc modification via GLUT3 and GFAT regulates cancer stem cell-like properties in colon and lung cancer cells.

GFPT1 CXCL8

5.09e-053144230305725
Pubmed

Clinicopathological and predictive significance of SIRT1 and peroxisome proliferator-activated receptor gamma in esophageal squamous cell carcinoma: The correlation with EGFR and Survivin.

SIRT1 EGFR

5.09e-053144229625788
Pubmed

The clinical value of the combined detection of sEGFR, CA125 and HE4 for epithelial ovarian cancer diagnosis.

MUC16 EGFR

5.09e-053144232016961
Pubmed

Pneumocystis-mediated IL-8 release by macrophages requires coexpression of mannose receptors and TLR2.

MRC1 CXCL8

5.09e-053144217020928
Pubmed

LTD₄ induces HB-EGF-dependent CXCL8 release through EGFR activation in human bronchial epithelial cells.

EGFR CXCL8

5.09e-053144220889674
Pubmed

Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirus.

ERVK-6 ERVK-11

5.09e-05314429971820
Pubmed

The C2 domains of otoferlin, dysferlin, and myoferlin alter the packing of lipid bilayers.

MYOF OTOF

5.09e-053144223859474
Pubmed

Role of SIRT1 in Streptococcus pneumoniae-induced human β-defensin-2 and interleukin-8 expression in A549 cell.

SIRT1 CXCL8

5.09e-053144224894820
Pubmed

Normal CFTR inhibits epidermal growth factor receptor-dependent pro-inflammatory chemokine production in human airway epithelial cells.

EGFR CXCL8

5.09e-053144223977375
Pubmed

Experimental diabetes mellitus exacerbates ischemia/reperfusion-induced myocardial injury by promoting mitochondrial fission: Role of down-regulation of myocardial Sirt1 and subsequent Akt/Drp1 interaction.

DNM1L SIRT1

5.09e-053144230381241
Pubmed

PPARα agonist fenofibrate attenuates TNF-α-induced CD40 expression in 3T3-L1 adipocytes via the SIRT1-dependent signaling pathway.

SIRT1 CD40

5.09e-053144223603572
Pubmed

CD40-CD40 ligand interactions in human microglia induce CXCL8 (interleukin-8) secretion by a mechanism dependent on activation of ERK1/2 and nuclear translocation of nuclear factor-kappaB (NFkappaB) and activator protein-1 (AP-1).

CD40 CXCL8

5.09e-053144217918746
Pubmed

Oncogenic KRAS-induced interleukin-8 overexpression promotes cell growth and migration and contributes to aggressive phenotypes of non-small cell lung cancer.

EGFR CXCL8

5.09e-053144221544811
Pubmed

ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import.

TNPO1 TNPO2

5.09e-053144220606625
Pubmed

Macrophage migration inhibitory factor and interleukin-8 produced by gastric epithelial cells during Helicobacter pylori exposure induce expression and activation of the epidermal growth factor receptor.

EGFR CXCL8

5.09e-053144218474653
Pubmed

Involvement of transportin 2-mediated HuR import in muscle cell differentiation.

TNPO1 TNPO2

5.09e-053144217475777
Pubmed

Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.

ERVK-10 ERVK-25 ERVK-11

5.42e-0518144318664271
Pubmed

Ring Finger Protein 11 acts on ligand-activated EGFR via the direct interaction with the UIM region of ANKRD13 protein family.

APOA2 MYOF EGFR QARS1

8.16e-0555144431985874
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

TNPO1 MTA2 NCAPD3 DNAH10 HSDL2 PCLO DNM1L APOB GRM1 GFPT1 IGF2R MRTO4 TDRD6 QARS1 ATP2B3 CLUH KIF11

8.95e-0514251441730948266
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

NCAPD3 KDM3B CBX4 ARID1A PARP14 WIZ TCF25 MRTO4

9.32e-05341144832971831
Pubmed

The mechanism of cleavage of EGFR ligands induced by inflammatory cytokines in gastric cancer cells.

EGFR CXCL8

1.02e-044144215300588
Pubmed

The nucleoporin Nup98 is a site for GDP/GTP exchange on ran and termination of karyopherin beta 2-mediated nuclear import.

TNPO1 TNPO2

1.02e-044144210875935
Pubmed

Activation of M3 muscarinic receptor by acetylcholine promotes non-small cell lung cancer cell proliferation and invasion via EGFR/PI3K/AKT pathway.

EGFR CXCL8

1.02e-044144225964092
Pubmed

Epidermal growth factor receptor reactivation induced by E-prostanoid-3 receptor- and tumor necrosis factor-alpha-converting enzyme-dependent feedback exaggerates interleukin-8 production in airway cancer (NCI-H292) cells.

EGFR CXCL8

1.02e-044144221925169
Pubmed

Resistance to arginine deiminase treatment in melanoma cells is associated with induced argininosuccinate synthetase expression involving c-Myc/HIF-1alpha/Sp4.

SP4 ASS1

1.02e-044144219934275
Pubmed

Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway.

SIRT1 HTT

1.02e-044144222179316
Pubmed

Gene polymorphisms of epidermal growth factor receptor and its downstream effector, interleukin-8, predict oxaliplatin efficacy in patients with advanced colorectal cancer.

EGFR CXCL8

1.02e-044144216098254
Pubmed

One of two chondrocyte-expressed isoforms of cartilage intermediate-layer protein functions as an insulin-like growth factor 1 antagonist.

CILP CILP2

1.02e-044144212746903
Pubmed

Karyopherin beta 2B participates in mRNA export from the nucleus.

TNPO1 TNPO2

1.02e-044144212384575
Pubmed

cbl-3: a new mammalian cbl family protein.

CBLC EGFR

1.02e-044144210362357
Pubmed

Immunohistochemical study of MMP-2, MMP-9, EGFR and IL-8 in decidual and trophoblastic specimens of recurrent pregnancy loss cases.

EGFR CXCL8

1.02e-044144237258409
Pubmed

Inhibition of metabotropic glutamate receptor signaling by the huntingtin-binding protein optineurin.

GRM1 HTT

1.02e-044144216091361
Pubmed

Molecular cloning and characterization of a novel cbl-family gene, cbl-c.

CBLC EGFR

1.02e-044144210571044
Pubmed

SH3 domain-dependent association of huntingtin with epidermal growth factor receptor signaling complexes.

EGFR HTT

1.02e-04414429079622
Pubmed

Transcriptional profiling uncovers a network of cholesterol-responsive atherosclerosis target genes.

HSDL2 APOB

1.02e-044144218369455
Pubmed

Conditional mutagenesis in mice with heat shock promoter-driven cre transgenes.

EGFR HTT

1.02e-044144210723724
Pubmed

Melatonin prevents Drp1-mediated mitochondrial fission in diabetic hearts through SIRT1-PGC1α pathway.

DNM1L SIRT1

1.02e-044144229575122
Pubmed

Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.

ERVK-6 ERVK-10

1.02e-04414427983737
Pubmed

Transportins 1 and 2 are redundant nuclear import factors for hnRNP A1 and HuR.

TNPO1 TNPO2

1.02e-044144215037768
Pubmed

Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.

APOB LGALS1 SPON1 FRZB

1.48e-0464144422261194
Pubmed

Iron metabolism mutant hbd mice have a deletion in Sec15l1, which has homology to a yeast gene for vesicle docking.

MYOF KIF11

1.69e-045144216289749
Pubmed

Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping.

ERVK-6 ERVK-7

1.69e-045144211401426
Pubmed

Identification of disulfide-linked apolipoprotein species in human lipoproteins.

APOA2 APOB

1.69e-04514428245722
Pubmed

Divergent roles of HDAC1 and HDAC2 in the regulation of epidermal development and tumorigenesis.

MTA2 EGFR

1.69e-045144224240174
Pubmed

MicroRNA 132 regulates nutritional stress-induced chemokine production through repression of SirT1.

SIRT1 CXCL8

1.69e-045144219819989
Pubmed

GGA2 interacts with EGFR cytoplasmic domain to stabilize the receptor expression and promote cell growth.

IGF2R EGFR

1.69e-045144229358589
Pubmed

Quantitation of HERV-K env gene expression and splicing in human breast cancer.

ERVK-6 ERVK-7

1.69e-045144212629516
Pubmed

Regulation of ubiquitin protein ligase activity in c-Cbl by phosphorylation-induced conformational change and constitutive activation by tyrosine to glutamate point mutations.

CBLC EGFR

1.69e-045144215117950
Pubmed

Knockdown of GnT-Va expression inhibits ligand-induced downregulation of the epidermal growth factor receptor and intracellular signaling by inhibiting receptor endocytosis.

LGALS1 EGFR

1.69e-045144219225046
Pubmed

Regulation of lysophosphatidic acid-induced epidermal growth factor receptor transactivation and interleukin-8 secretion in human bronchial epithelial cells by protein kinase Cdelta, Lyn kinase, and matrix metalloproteinases.

EGFR CXCL8

1.69e-045144216687414
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

MTA2 MTHFD2 CBX4 REV3L ARID1A SIRT1 EDEM3 MLH3 HMCN2 WIZ KMT5B ASS1 TCF25 TOPORS

2.33e-0411161441431753913
Pubmed

Mutations in a Sar1 GTPase of COPII vesicles are associated with lipid absorption disorders.

APOA2 APOB

2.53e-046144212692552
Pubmed

Genetic and dietary interactions in the regulation of HMG-CoA reductase gene expression.

APOA2 APOB

2.53e-04614421352323
Pubmed

Divergent Roles for Macrophage C-type Lectin Receptors, Dectin-1 and Mannose Receptors, in the Intestinal Inflammatory Response.

MRC1 IGF2R

2.53e-046144232234475
Pubmed

Cyclin D1 and epidermal growth factor polymorphisms associated with survival in patients with advanced colorectal cancer treated with Cetuximab.

EGFR CXCL8

2.53e-046144216788380
Pubmed

cbl-b inhibits epidermal growth factor receptor signaling.

CBLC EGFR

2.53e-046144210086340
Cytoband9p13.1

SPATA31A3 SPATA31A1 FAM74A3

5.95e-052414539p13.1
CytobandEnsembl 112 genes in cytogenetic band chr9q12

SPATA31A7 SPATA31A5

2.74e-0481452chr9q12
GeneFamilyFerlin family

MYOF OTOF

3.79e-046922828
GeneFamilyGlutamate metabotropic receptors|Protein phosphatase 1 regulatory subunits

GRM1 GRM6

7.03e-048922281
GeneFamilyKinesins|Pleckstrin homology domain containing

KIF18A KIF26A KIF11

1.65e-0346923622
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_VASCULAR_SMC_2_CELL

ABR NTF3 MTHFD2 OLFML2B GATM PDLIM5 FRZB CTNNA3

2.73e-061711338M45687
CoexpressionBONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING

TNPO1 CILP TNPO2 GRK6 GATM REV3L SIRT1 DUS1L EDEM3 MYOF WIZ FUT4

1.09e-0550613312M253
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500

NTF3 OLFML2B GATM MUC16 REV3L MYOF TENM4 EGFR EEPD1 ENPEP WNK3

2.54e-0537313411gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000

OLFML2B GATM MUC16 REV3L GFPT1 LGALS1 AKR1E2 MYOF IGF2R TENM4 EGFR EEPD1 ASS1 ENPEP WNK3 KIF11

3.03e-0577313416gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000

NTF3 OLFML2B GATM MUC16 LRRC4C THSD7B REV3L LGALS1 MYOF IGF2R TENM4 EGFR EEPD1 ASS1 ENPEP WNK3

3.22e-0577713416gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_1000
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_3|E16.5-samps / Age Group, Lineage, Cell class and subclass

PCDHGB2 DUS1L IGF2R CTNNA3 LRP3 ENPEP KIF11

4.28e-071491387651494e84be03dc7b061ebdfa91756a1c507b9b4
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 CTTNBP2 ABR FERMT1 MYOF DRAXIN TRMT13

1.31e-0617613875e46a09a36b9645b1b1fcb0b64bd0898561af3a9
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CILP MTHFD2 GATM EEPD1 DEPDC7 ATP4A KIF11

1.70e-0618313876c1d7ce60e67bf1df364a4e177c351e7313eb41f
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 PCLO APOB LRRC4C GRM1 TENM4 XIRP2

1.76e-0618413872cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 PCLO APOB LRRC4C GRM1 TENM4 XIRP2

1.76e-061841387ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 PCLO APOB LRRC4C GRM1 TENM4 XIRP2

1.76e-0618413872b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

NTF3 MTHFD2 OLFML2B GATM PDLIM5 FRZB CTNNA3

1.96e-061871387406ff9327d3109fe1e251629c4c617b00a573dc2
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NTF3 OLFML2B GATM PDLIM5 FRZB CTNNA3 ENPEP

2.18e-061901387d6b3a92119b210974a32af3fe9875d60eb02761e
ToppCell18-Distal-Mesenchymal-Pericyte|Distal / Age, Tissue, Lineage and Cell class

NTF3 MTHFD2 OLFML2B GATM PDLIM5 FRZB ENPEP

2.59e-061951387e0ee7905499ee1a1ca7b1184e2713028cf156985
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ARHGEF28 MUC16 THSD7B PKD1L3 GRM6 HMCN2 CXCL8

2.59e-061951387d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ARHGEF28 MUC16 THSD7B PKD1L3 GRM6 HMCN2 CXCL8

2.59e-06195138719853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell356C-Myeloid-Dendritic-cDC2|356C / Donor, Lineage, Cell class and subclass (all cells)

MRC1 GATM REV3L CHML CD40 CACNA2D3 CXCL8

2.59e-0619513874c9a2167d8cfe40dfd609c303ada5b5ef800bd8f
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NTF3 MTHFD2 OLFML2B PDLIM5 FRZB CTNNA3 ENPEP

2.77e-061971387cc494a656db868bb489238a5becc31bc8518f3cc
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CILP NTF3 OLFML2B PDLIM5 MYOF FRZB CTNNA3

3.06e-0620013879169a9ec8e9ab95d90a64c5a19ac666a5cf82313
ToppCell367C-Myeloid-Macrophage-SPP1+_Macrophage_3|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

C1orf167 REV3L HMCN2 ASS1 WNK3 CXCL8

8.96e-061551386335cd798afbaa0a3a3e1dc558a81cfa32da48983
ToppCell21-Trachea-Epithelial-Submucosal_gland_basal|Trachea / Age, Tissue, Lineage and Cell class

DCHS2 COL9A3 FERMT1 THSD7B PSORS1C1 FRZB

1.04e-0515913864f670b57b8d3b090ea2f1aafe15baf93cb7ef146
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Macrophage-macrophage,_alveolar-Macro_c6-VCAN|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GRM6 RNF227 KIRREL3 LIPT1 MIGA2 CRLF3

1.07e-0516013868374ae912337947b2cc8d17d5840f306361fe1ff
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF18A NCAPD3 ARHGEF28 CHML SHPRH MRTO4

1.19e-051631386a24db9d266a40f3bffe4f18d277bc269791b4560
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTTNBP2 ABR FERMT1 MYOF OTOF DRAXIN

1.62e-0517213863f784aed340b50ddbec3f7dc0a5279180d38a2bb
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NTF3 OLFML2B GRM1 LGALS1 SPON1 CTNNA3

1.67e-0517313865c55e1e27e9e3e77600d378cc87b51cc73907527
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

APOB LGALS1 OTOF FRZB TRMT13 CLEC16A

1.73e-051741386c529f3674b784f872f4387ffdeb46aecb619976b
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PAMR1 KIRREL3 EGFR SPON1 FRZB TDRD6

1.90e-0517713863d955ea938a1d2fb1b6d68d4997fd454bd632dfc
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 CTTNBP2 ABR FERMT1 MYOF DRAXIN

1.90e-05177138614fb8d182775dfd0e49aa7e4e12543a85b3b8bd6
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NTF3 MTHFD2 OLFML2B LGALS1 SPON1 CTNNA3

1.90e-0517713864553ee8cd9c24db6511b09fe49ed11a89e7cde9e
ToppCellP28-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL9A3 OLFML2B GATM LRRC4C ZFYVE28 FRZB

2.09e-0518013861e819c5c87704ec6535dfeaae56561895e239d07
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo-stroma-chondrocyte|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL9A3 PAMR1 CILP2 FRZB ASS1 TTC22

2.52e-05186138680a0a42ca8585cdb1dda57a18c254316a126ee64
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NTF3 MTHFD2 PDLIM5 FRZB CTNNA3 ENPEP

2.67e-051881386c2321a3a1d9603f8b4b4fc09707eb32ec1e04f3f
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NTF3 MTHFD2 PDLIM5 FRZB CTNNA3 ENPEP

3.01e-051921386dee97f650ae6f4d07a142ade402aae1905791a22
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CILP PAMR1 OLFML2B LGALS1 HMCN2 FRZB

3.10e-051931386dc8e62df6121ee99b156aca6b1b3ae555739b6f2
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

COL9A3 PAMR1 LGALS1 MYOF SPON1 ENPEP

3.10e-051931386cd45118ced91b10baed3b1068d4673ec99824b86
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

NTF3 MTHFD2 GATM PDLIM5 FRZB CTNNA3

3.10e-051931386360079cbaa18b74e4a48c5de40844faca076e1a6
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CILP PAMR1 OLFML2B LGALS1 HMCN2 FRZB

3.10e-051931386e2ee077fd381bd906e6b4329f22e7d106e422a7f
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

CILP PAMR1 KIRREL3 TENM4 HMCN2 EGFR

3.19e-051941386d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MTHFD2 OLFML2B PDLIM5 FRZB CTNNA3 ENPEP

3.28e-051951386815ac5dacd382b11abb32011ed1c0635b0ddc779
ToppCellwk_20-22-Hematologic-Myeloid-S100A12-lo_cla._mono.|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

MRC1 PLB1 GATM APOA2 CACNA2D3 CXCL8

3.28e-05195138666273af9882f829b6fc0e20f03f3412294d37c26
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MTHFD2 OLFML2B PDLIM5 FRZB CTNNA3 ENPEP

3.38e-051961386624f700daea48d9bad4cc554f4776bd809ae1e54
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF26A LRRC4C DRAXIN ASS1 SYT5 ATP2B3

3.47e-051971386fd43fc1cbf0c17b370397d73dddc572565a759c7
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MTHFD2 OLFML2B PDLIM5 FRZB CTNNA3 ENPEP

3.47e-0519713861c91e3afcc5be195b827a1dff83aff5cc2492456
ToppCell3'_v3-GI_small-bowel-Myeloid_Mac|GI_small-bowel / Manually curated celltypes from each tissue

THEMIS2 MRC1 OLFML2B GATM EEPD1 CXCL8

3.67e-0519913868990a3d69e24cb3aaba9d6def3d0be9ee973436d
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-Pericytes|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MTHFD2 OLFML2B PDLIM5 FRZB CTNNA3 ENPEP

3.67e-051991386f1723cfd6fbb8c8903a3b167872ec8523e3be250
ToppCellParenchymal-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CTTNBP2 OLFML2B RNF40 TENM4 ZNF540 ASS1

3.67e-0519913866f5ef959b51eccf1ffc2e5ddf0d83c62ca2257b2
ToppCellParenchymal-NucSeq-Stromal-Peri/Epineurial_|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CTTNBP2 OLFML2B RNF40 TENM4 ZNF540 ASS1

3.67e-0519913861aa99d21bf61b86df4a966dc47634044430aa39f
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL9A3 PAMR1 OLFML2B LGALS1 SPON1 ENPEP

3.67e-05199138683383d9ae4f501754fd3da0215ce6f0e3c70562c
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CILP NTF3 OLFML2B MYOF FRZB CTNNA3

3.78e-052001386a3a1e35934d676c39f917652e50c502cb2f613c1
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ABR NTF3 OLFML2B PDLIM5 FRZB CTNNA3

3.78e-052001386c06426f877919bdd267ea2fd7e7973c6619832ae
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte|LPS_only / Treatment groups by lineage, cell group, cell type

CILP NTF3 OLFML2B MYOF FRZB CTNNA3

3.78e-0520013868c8ef2b19ab5b1bfc0fae6c38a330f464f28e86f
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_3|Control_saline / Treatment groups by lineage, cell group, cell type

ABR NTF3 OLFML2B PDLIM5 FRZB CTNNA3

3.78e-052001386b0866b497aa71d06cef25f9a335fa584e95fa7e0
ToppCellLV-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

CBX4 GRM1 PDLIM5 XIRP2 CTNNA3

5.31e-051301385a3e12984fb61311e49cc76c59f74f4dffc48faa1
ToppCellCOVID-19-kidney-Technical/muscle_(EC)|kidney / Disease (COVID-19 only), tissue and cell type

MUC16 LRRC4C THSD7B KIRREL3 CTNNA3

7.30e-05139138564c35411bbe67acb5010dadc4b0b1be0f8b17737
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

LRRC4C THSD7B GRM1 KIRREL3 CTNNA3

9.21e-051461385c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCellClub_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

CILP FERMT1 PLPP2 TRMT13 TDRD6

9.51e-0514713855a824c89e4d045af465d7333275f8191fb29b041
ToppCellE16.5-samps-Myeloid-Fetal_macrophage-macrophage_-_intermediate_-_unactivated|E16.5-samps / Age Group, Lineage, Cell class and subclass

THEMIS2 MRC1 GATM APOB DRAXIN

1.05e-04150138560fdd266aaca1b589b9a77465a4a7fad4921339a
ToppCellChildren_(3_yrs)-Immune-dendritic_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

NTF3 C2orf78 KIRREL3 TENM4 HPS5

1.11e-0415213850769857f25da2e6169420818e61d65e33b7277b1
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

COL9A3 PAMR1 LGALS1 DRAXIN TOPORS

1.22e-0415513859d53caee196b5c2bbc90c4f54f693b64d4086065
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_VISp_Adamts2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ARHGEF28 NTF3 GATM KCNH3 OTOF

1.26e-0415613852cd007b423c2395c5ce331902e7f27c805755eb3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CTTNBP2 FERMT1 GRM6 KIRREL3 PSORS1C1

1.33e-041581385e7db0ee4740e3c7a4d97d7cd7462e2c2ab458a4b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CTTNBP2 FERMT1 GRM6 KIRREL3 PSORS1C1

1.33e-041581385d39e020c3e77eb9d3de600a171d22f94357061d4
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

LRRC4C THSD7B KIRREL3 XIRP2 CTNNA3

1.37e-0415913855335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLB1 CTTNBP2 DNAH10 TDRD6 CACNA2D3

1.41e-041601385c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLB1 CTTNBP2 DNAH10 TDRD6 CACNA2D3

1.41e-04160138525c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell367C-Fibroblasts-Fibroblast-F|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

DNAH10 SEMA3G GRM6 SYT5 KIF11

1.46e-041611385c61283c301a87bb802f6f8ce79c26067032dd7d9
ToppCell367C-Fibroblasts-Fibroblast-F-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

DNAH10 SEMA3G GRM6 SYT5 KIF11

1.46e-0416113859864d8b0929dacf4be7a4e97d2527ac3120ea264
ToppCellClub_cells-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

CBLC APOB KIRREL3 PLPP2 OTOF

1.59e-0416413854e25e6362ef793b08de2f4d1dccb6b1fc9c072a5
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GATM LRRC4C ASS1 CTNNA3 TDRD12

1.73e-0416713853edb0570e583bb527165bcd8a4c25a042054043b
ToppCelldroplet-Marrow-BM-1m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL9A3 INTS7 MYOF ASS1 ATP4A

1.78e-0416813852e88d9cb7c80a4656fab290db8b45a5a0599d769
ToppCellnormal_Lymph_Node-Myeloid_cells-CD163+CD14+_DCs|normal_Lymph_Node / Location, Cell class and cell subclass

ATP8B3 MRC1 OLFML2B MYOF CXCL8

2.04e-04173138538f88f5bbf92a3bf5109bc4782cd071b7cb1ca34
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

OLFML2B GRM1 LGALS1 SPON1 CTNNA3

2.09e-041741385778e0317c0c63fa4efd74114feb760975b819d92
ToppCellAdult-Epithelial-basal_cell-D231|Adult / Lineage, Cell type, age group and donor

NTF3 C2orf78 CILP2 PLPP2 EGFR

2.09e-041741385a4f98afe7d1cc2617f6f7bc8092c41df57474b30
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 GRM1 MYOF CLUH CXCL8

2.09e-041741385207aa0118633cbe9a65839bbb1bb3ba9f8118ad2
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1-3_PAX6_NABP1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CFAP47 NTF3 PDLIM5 CILP2 EEPD1

2.15e-041751385f7f8c16e81b26748a5323d70c542d06c02eccdff
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|368C / Donor, Lineage, Cell class and subclass (all cells)

KIF18A KIF26A PCLO KIF11 TDRD12

2.15e-041751385fd8b5b756f3df4a04938785f3d9edbb6f1cd20f6
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|368C / Donor, Lineage, Cell class and subclass (all cells)

KIF18A KIF26A PCLO KIF11 TDRD12

2.15e-04175138536c140540497bbe1c5f08fac2d94f08cac18fabb
ToppCellfacs-Marrow-B-cells-18m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFYVE28 KCNH6 PRG3 SPON1 SYT5

2.20e-0417613855f9ae5eb45603ed0422a3a993ecdbe2ce05d6e45
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MTHFD2 OLFML2B GATM CTNNA3 ENPEP

2.20e-0417613858b5c2fb7e5e551df658b1d5fc7f607a27bab00d5
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_3|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

PAMR1 KIRREL3 SPON1 FRZB TDRD6

2.20e-041761385bfa1633e1b7a8a2f04d37fa07284fe9bc0199f46
ToppCelldroplet-Fat-SCAT-30m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CILP KIRREL3 DRAXIN FRZB CACNA2D3

2.32e-0417813855cf12927f0756c4d8a289fe4308d736382e6212e
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

OLFML2B THSD7B FRZB CTNNA3 ENPEP

2.32e-041781385066dbc4cc2083c549d98122ed44707127f34d582
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_THTPA|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TPMT OLFML2B THSD7B SPON1 CTNNA3

2.32e-041781385e4e11e4940c911c17806200c25096928153c684d
ToppCelldroplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGEF28 KCNH3 PRG3 CD40 SYT5

2.38e-0417913854f20540bfbcefe0e83812be7ea542e8bb3bf19bc
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF28 OLFML2B TENM4 EGFR CACNA2D3

2.38e-041791385fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCelldroplet-Lung-nan-21m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF28 KCNH3 PRG3 CD40 SYT5

2.38e-041791385d78eacf47847a50888dd16c35bed9b7afc80010f
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-6_VIP_RGS16|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGEF28 PDLIM5 KCNH6 HMCN2 EGFR

2.38e-0417913855bf191bdc0c32bce83ab5c38f0616e209e420e55
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CTTNBP2 PCLO KCNH6 ASS1 ENPEP

2.45e-041801385f8bdfd7bf7b3d52c659a29d8f5f80858e79da83e
ToppCellE15.5-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

OLFML2B LGALS1 IGF2R SPON1 CTNNA3

2.45e-04180138538035cf2c6fbc443ea10ca7e942572715ed572da
ToppCellBronchial_Biopsy-Mesenchymal-Smooth_muscle|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

KIF26A SEMA3G FRZB CTNNA3 ENPEP

2.45e-0418013857085a851807e6a833965e1366946db0bbc5174e2
ToppCellsevere_influenza-B_memory|severe_influenza / disease group, cell group and cell class (v2)

GATM MUC16 PLPP2 CD40 BANK1

2.51e-04181138592e572c92109a6dae0f73138c57c3bbd2e0a2f36
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CTTNBP2 PAMR1 APOB SPON1 DEPDC7

2.51e-041811385b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCelltumor_Lung-Myeloid_cells-pDCs|tumor_Lung / Location, Cell class and cell subclass

THEMIS2 CHML TMEM210 KIRREL3 IGF2R

2.51e-041811385c864ffeb9234b8c29754afc91c85a972889617f4
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THEMIS2 MRC1 GATM MYOF KIF11

2.57e-04182138521dcab170ffeef89faa9fee5008568cb6e15c694
ToppCelldroplet-Limb_Muscle-nan-21m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL9A3 GATM ZFYVE28 FRZB CTNNA3

2.57e-041821385a512863304fad80acaab60a8c6107eb7c9cbac99
ToppCelldroplet-Lung-nan-18m-Myeloid-Proliferating_Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MTHFD2 GATM DEPDC7 ATP4A KIF11

2.57e-04182138511494a66d986297b837332ee9d382b71b9f22591
ToppCellwk_20-22-Mesenchymal-Chondrocyte-Resting_chondrocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

COL9A3 PCLO CILP2 TENM4 FRZB

2.57e-04182138503a5a02acd48f0eb210485348bfe0cd21f486215
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF28 HSDL2 TENM4 EGFR CACNA2D3

2.57e-04182138517ed11a7ea366dd3106400511d5e628d3f1a9c3e
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

MRC1 OLFML2B MYOF CCL3L1 DEPDC7

2.57e-041821385c3fb1460160744144aa31afc76c0a4d42ebdeb91
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D175|Adult / Lineage, Cell type, age group and donor

CTTNBP2 C1orf167 THSD7B TENM4 CD40

2.57e-041821385ad4d74d8b19976e1ccc3c5ba8013199338cf6fd8
ToppCellAdult-Epithelial-basal_cell|Adult / Lineage, Cell type, age group and donor

NTF3 FERMT1 C2orf78 PLPP2 EGFR

2.64e-04183138500a6b19ca49e3b8e0d1cd387a3515b0ff4b81c81
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

ARHGEF28 NTF3 MYOF HMCN2 ENPEP

2.64e-041831385818fd886e0188091310825f9145fa53328f2c979
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DCHS2 COL9A3 FERMT1 LRRC4C SPON1

2.64e-041831385d73cac83cde82665f110baad7cf28db75f9ffe52
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Monocytic-Nonclassical_Monocyte|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MRC1 LGALS1 ANKRD33 CCL3L1 CXCL8

2.64e-0418313854cc0961a67de76b8d756cd9ffcaa98e3fe3c3a69
ToppCellControl-Epithelial_cells-Airway_mucous|Control / group, cell type (main and fine annotations)

ARHGEF28 MUC16 CBLC EEPD1 ASS1

2.64e-04183138515d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
Diseasevery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

DNAH10 CBLC APOA2 APOB ARID1A IGF2R TENM4 EEPD1 BANK1 HTT

7.01e-0729113010EFO_0008317, EFO_0020946
Diseaseapolipoprotein B measurement

DCHS2 SP4 DNAH10 GRK6 CBLC APOB PKD1L3 ARID1A MYOF CILP2 IGF2R PSORS1C1 HTT

7.81e-0666313013EFO_0004615
Diseaseintellectual developmental disorder with hypotonia, impaired speech, and dysmorphic facies (implicated_via_orthology)

TNPO1 TNPO2

1.93e-0521302DOID:0081262 (implicated_via_orthology)
Diseaserisk-taking behaviour

KIF26A LRRC4C THSD7B REV3L PKD1L3 RNF227 KIRREL3 TENM4 TULP4 PSORS1C1 CD40 BANK1 HTT

3.45e-0576413013EFO_0008579
Diseasesleep duration, low density lipoprotein cholesterol measurement

CBLC APOB PKD1L3 IGF2R HTT

5.28e-05911305EFO_0004611, EFO_0005271
Diseasecholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement

CBLC APOA2 APOB ARID1A BANK1

9.52e-051031305EFO_0008595, EFO_0020944
Diseasefamilial hyperlipidemia

CBLC APOB ARID1A CILP2 IGF2R

1.09e-041061305MONDO_0001336
Diseasehigh density lipoprotein particle size measurement

DNAH10 APOA2 APOB CD40 ATP4A BANK1

1.11e-041701306EFO_0008592
DiseaseInsulin Resistance

MRC1 SIRT1 EGFR CD40

1.45e-04601304C0021655
DiseaseInsulin Sensitivity

MRC1 SIRT1 EGFR CD40

1.45e-04601304C0920563
Diseasecholesteryl ester measurement

DNAH10 APOA2 APOB ARID1A IGF2R CD40 BANK1

1.49e-042571307EFO_0010351
DiseaseBehcet Syndrome

APOB PSORS1C1 CXCL8

1.58e-04241303C0004943
DiseaseLumbar disc disease

COL9A3 CILP

1.91e-0451302C0221775
DiseaseINTERVERTEBRAL DISC DISEASE

COL9A3 CILP

1.91e-0451302603932
DiseaseIntervertebral disc disorder

COL9A3 CILP

1.91e-0451302cv:C0158252
Diseasecholesterol in large VLDL measurement

DNAH10 APOB ARID1A IGF2R

1.98e-04651304EFO_0021902
Diseasecholesterol in very large VLDL measurement

DNAH10 APOB ARID1A IGF2R

1.98e-04651304EFO_0022230
Diseaselevel of Sterol ester (27:1/16:0) in blood serum

CBLC APOB TTC22

2.02e-04261303OBA_2045191
Diseaseattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement

CTTNBP2 KIF26A LRRC4C THSD7B REV3L RNF227 TENM4 TULP4 CD40 CTNNA3 HPS5 CACNA2D3

2.28e-0480113012EFO_0003888, EFO_0007052, MONDO_0002491
Diseasetriglycerides to phosphoglycerides ratio

DNAH10 APOB ARID1A BANK1

2.35e-04681304EFO_0022327
DiseaseStreptococcal pneumonia

SIRT1 CXCL8

2.86e-0461302C0155862
Diseasefamilial combined hyperlipidemia (is_marker_for)

APOA2 APOB

2.86e-0461302DOID:13809 (is_marker_for)
DiseaseIntervertebral disc disorder

COL9A3 CILP

2.86e-0461302C0158252
DiseaseEndometrial Carcinoma

ARID1A MLH3 EGFR CXCL8

2.93e-04721304C0476089
Diseasehepatocellular carcinoma (is_marker_for)

APOA2 CBX4 ARID1A IGF2R EGFR ASS1 CXCL8

3.89e-043011307DOID:684 (is_marker_for)
DiseaseLDL cholesterol change measurement

APOB PKD1L3

3.99e-0471302EFO_0007804
Diseaselimb-girdle muscular dystrophy (implicated_via_orthology)

MYOF OTOF

3.99e-0471302DOID:11724 (implicated_via_orthology)
DiseaseLiver carcinoma

MAGEA3 KIF18A PAMR1 OLFML2B ARID1A IGF2R EGFR KIF11 CXCL8

4.27e-045071309C2239176
Diseasetotal cholesterol measurement, very low density lipoprotein cholesterol measurement

SP4 DNAH10 CBLC APOB ARID1A IGF2R

4.88e-042241306EFO_0004574, EFO_0008317
Diseasecholesteryl ester measurement, very low density lipoprotein cholesterol measurement

SP4 DNAH10 CBLC APOB ARID1A IGF2R

5.00e-042251306EFO_0008317, EFO_0010351
DiseaseFamilial hypercholesterolemia

APOA2 APOB

5.30e-0481302cv:C0020445
Diseaseserum metabolite measurement

TNPO1 GRK6 PKD1L1 GATM APOB REV3L C2orf78 GTF2B IGF2R KMT5B HPS5 ENPEP

9.86e-0494513012EFO_0005653
DiseaseUnipolar Depression

NTF3 PCLO GRM1 PDLIM5 EGFR ENPEP

1.04e-032591306C0041696
Diseasevery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

DNAH10 CBLC APOB IGF2R EEPD1 HTT

1.15e-032641306EFO_0008317, EFO_0020944
DiseaseOsteosarcoma

SIRT1 EGFR TOPORS

1.18e-03471303C0029463
Diseasehepatocellular carcinoma (is_implicated_in)

CBX4 ARID1A IGF2R ASS1 CXCL8

1.27e-031811305DOID:684 (is_implicated_in)
Diseaseapolipoprotein A 1 measurement, apolipoprotein B measurement

DNAH10 CBLC APOB ARID1A

1.31e-031071304EFO_0004614, EFO_0004615
Diseasecholesteryl esters to total lipids in IDL percentage

APOB ARID1A BANK1

1.41e-03501303EFO_0022247
DiseaseAlzheimer disease

MRC1 RAPGEF6 NTF3 CBLC EGFR SPON1 BANK1 CACNA2D3

1.42e-034851308MONDO_0004975
DiseaseHyperlipoproteinemia Type IIb

APOA2 APOB

1.46e-03131302C1704417
Diseasealcohol use disorder (implicated_via_orthology)

GRK6 KDM3B ARID1A SIRT1 EGFR

1.76e-031951305DOID:1574 (implicated_via_orthology)
Diseasetriglycerides in medium VLDL measurement

DNAH10 APOB ARID1A

1.85e-03551303EFO_0022155
Diseasephospholipids in medium HDL measurement

APOA2 APOB ARID1A

1.85e-03551303EFO_0022295
Diseasetriglycerides in large VLDL measurement

DNAH10 APOB ARID1A

1.95e-03561303EFO_0022178
Diseaselow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

DNAH10 CBLC APOB BANK1 HTT

1.96e-032001305EFO_0004611, EFO_0020945
Diseaselymphocyte count

THEMIS2 TNPO1 DNAH10 PCDHGB2 CHML GTF2B CILP2 CCDC66 TENM4 PLPP2 EGFR CRLF3 CD40 CLEC16A HTT

2.02e-03146413015EFO_0004587
Diseasepre-eclampsia (is_marker_for)

GATM ARID1A CD40

2.16e-03581303DOID:10591 (is_marker_for)
DiseaseEndometrial Neoplasms

ARID1A MLH3 CXCL8

2.16e-03581303C0014170
DiseaseObesity

MRC1 GFPT1 SIRT1 CD40 VPS13B

2.19e-032051305C0028754
DiseaseHyperlipoproteinemia Type IIa

APOA2 APOB

2.22e-03161302C0745103
Diseasefree cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

CBLC APOA2 APOB ARID1A CD40 BANK1

2.30e-033031306EFO_0004612, EFO_0020945
Diseasetotal lipids in VLDL measurement

APOB ARID1A IGF2R

2.38e-03601303EFO_0022314
Diseasecholesterol to total lipids in IDL percentage

APOB ARID1A BANK1

2.38e-03601303EFO_0022233
Diseasetriglycerides in small VLDL measurement

DNAH10 APOB ARID1A

2.50e-03611303EFO_0022145
Diseaseacute kidney failure (biomarker_via_orthology)

GATM SIRT1 EGFR

2.50e-03611303DOID:3021 (biomarker_via_orthology)
Diseasefree cholesterol in very large VLDL measurement

DNAH10 APOB ARID1A

2.50e-03611303EFO_0022274
Diseasephospholipids in large VLDL measurement

DNAH10 APOB ARID1A

2.61e-03621303EFO_0022169
Diseasetriglycerides in medium LDL measurement

APOB ARID1A IGF2R

2.61e-03621303EFO_0022322
Diseasetotal lipids in very large VLDL measurement

DNAH10 APOB ARID1A

2.61e-03621303EFO_0022313
Diseasephospholipids in very large VLDL measurement

DNAH10 APOB ARID1A

2.61e-03621303EFO_0022299
Diseasefree cholesterol measurement, very low density lipoprotein cholesterol measurement

SP4 DNAH10 APOB ARID1A IGF2R

2.69e-032151305EFO_0008317, EFO_0008591
Diseasefree cholesterol measurement, high density lipoprotein cholesterol measurement

DNAH10 APOA2 APOB ARID1A EEPD1 CD40

2.78e-033151306EFO_0004612, EFO_0008591
Diseasetotal cholesterol measurement, high density lipoprotein cholesterol measurement

DNAH10 APOA2 APOB ARID1A EEPD1 CD40

2.78e-033151306EFO_0004574, EFO_0004612
Diseasebehavior or behavioral disorder measurement, personality trait

INTS7 LRRC4C

2.81e-03181302EFO_0004365, EFO_0004782
DiseaseHypercholesterolemia, Familial

APOA2 APOB

2.81e-03181302C0020445
Diseasephospholipid measurement, high density lipoprotein cholesterol measurement

DNAH10 APOA2 APOB ARID1A EEPD1 CD40

3.06e-033211306EFO_0004612, EFO_0004639
Diseasetotal lipids in very large HDL measurement

APOA2 APOB BANK1

3.12e-03661303EFO_0022312
Diseasephospholipids in very large HDL measurement

APOA2 APOB BANK1

3.12e-03661303EFO_0022298
Diseasetype 2 diabetes mellitus (is_marker_for)

APOA2 APOB GFPT1 FRZB

3.13e-031361304DOID:9352 (is_marker_for)
DiseaseDown Syndrome, Partial Trisomy 21

NTF3 CXCL8

3.14e-03191302C0432416
DiseaseTrisomy 21, Meiotic Nondisjunction

NTF3 CXCL8

3.14e-03191302C0432417
DiseaseTrisomy 21, Mitotic Nondisjunction

NTF3 CXCL8

3.14e-03191302C0751081
DiseaseDown Syndrome

NTF3 CXCL8

3.14e-03191302C0013080
DiseaseSystemic Scleroderma

SIRT1 PSORS1C1

3.14e-03191302C0036421
Diseasereasoning

LRRC4C ANKRD33

3.14e-03191302EFO_0004350
Diseasetotal lipids in small VLDL

DNAH10 APOB IGF2R

3.26e-03671303EFO_0022148
Diseasetotal lipids in large VLDL

DNAH10 APOB ARID1A

3.26e-03671303EFO_0022175
DiseaseGrand Mal Status Epilepticus

NTF3 GRM1 CD40

3.26e-03671303C0311335
Diseasephospholipids:total lipids ratio, intermediate density lipoprotein measurement

APOA2 APOB BANK1

3.26e-03671303EFO_0008595, EFO_0020946
Diseaseradiation-induced disorder

DCHS2 PDLIM5 KIRREL3

3.26e-03671303EFO_0009565
DiseaseStatus Epilepticus, Subclinical

NTF3 GRM1 CD40

3.26e-03671303C0751522
DiseaseSimple Partial Status Epilepticus

NTF3 GRM1 CD40

3.26e-03671303C0751524
DiseaseNon-Convulsive Status Epilepticus

NTF3 GRM1 CD40

3.26e-03671303C0751523
DiseasePetit mal status

NTF3 GRM1 CD40

3.26e-03671303C0270823
DiseaseComplex Partial Status Epilepticus

NTF3 GRM1 CD40

3.26e-03671303C0393734
Diseasephospholipids:total lipids ratio

APOA2 APOB ARID1A IGF2R BANK1

3.39e-032271305EFO_0020946
DiseaseStatus Epilepticus

NTF3 GRM1 CD40

3.40e-03681303C0038220
Diseasefree cholesterol in large VLDL measurement

DNAH10 APOB ARID1A

3.40e-03681303EFO_0022265
Diseasemetabolite measurement

GRK6 GATM REV3L PDLIM5 MYOF IGF2R HPS5 ENPEP

3.45e-035601308EFO_0004725
Diseaseatherosclerosis (biomarker_via_orthology)

SIRT1 CD40

3.47e-03201302DOID:1936 (biomarker_via_orthology)
Diseasecitrulline measurement

HMCN2 ASS1

3.47e-03201302EFO_0009777
Diseaselipid measurement, high density lipoprotein cholesterol measurement

DNAH10 APOA2 APOB ARID1A EEPD1 CD40

3.50e-033301306EFO_0004529, EFO_0004612
Diseasevery low density lipoprotein cholesterol measurement, phospholipid measurement

SP4 DNAH10 APOB ARID1A IGF2R

3.52e-032291305EFO_0004639, EFO_0008317
Diseasecholesterol in very large HDL measurement

APOA2 APOB BANK1

3.54e-03691303EFO_0022229
DiseaseST2 protein measurement

KIRREL3 BANK1

3.83e-03211302EFO_0010599
Diseasegestational age, birth measurement

OLFML2B CACNA2D3

3.83e-03211302EFO_0005112, EFO_0006921
Diseaseskin hydration measurement

PKD1L1 LRRC4C

3.83e-03211302EFO_0009586
DiseaseColorectal Carcinoma

APOB GRM1 ARID1A GTF2B MLH3 EGFR ZNF540 C12orf76 CXCL8

3.99e-037021309C0009402
Diseasetriglycerides to total lipids in small HDL percentage

APOB ARID1A BANK1

3.99e-03721303EFO_0022336
Diseasetype 1 diabetes mellitus (is_marker_for)

APOA2 APOB CD40

3.99e-03721303DOID:9744 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
PYIVRQCVEEVEKRG

ABR

661

Q12979
QLRDCIIGKRPEEEN

BANK1

721

Q8NDB2
EIQPCLAESRAAREK

RNF40

886

O75150
RVKQCPGSLREEEIA

C1orf167

586

Q5SNV9
PGKEASEQRIRELCG

COL9A3

516

Q14050
LEGALVRRQAKEPCV

APOA2

16

P02652
KNPECLLEREVVVGS

C2orf78

521

A6NCI8
EVQERLQACRDKPGS

CBLC

246

Q9ULV8
PVARKLSAREQRDCE

DNM1L

631

O00429
EKLNLRGCEVVPDVN

FERMT1

416

Q9BQL6
RGCEVVPDVNVAGRK

FERMT1

421

Q9BQL6
RCQEEISRQEGAKPT

DUS1L

311

Q6P1R4
CVGDVVCLRKDNIVP

ATP8B3

236

O60423
GDVDIPRAKVVRVCQ

DEPDC7

86

Q96QD5
CSVEKANNPGVREVV

EEPD1

271

Q7L9B9
EVPEAIRKCQRAGIT

ATP2B3

686

Q16720
PCIARKQVEIAQREG

ASS1

96

P00966
LAFREGKVEQVPCSR

CHML

266

P26374
EIRVGCKYQAEIPDR

MTA2

146

O94776
NRCADLTAVDPVRGK

ANKRD33

211

Q7Z3H0
NGEDEKCRSFRSVVP

GSG1L2

101

A8MUP6
GKLGEQCEAVVRFPR

INTS7

36

Q9NVH2
KGDLIGCELPRREQV

KCNH3

641

Q9ULD8
GCELPRREQVVKANA

KCNH3

646

Q9ULD8
DVVERLREKCSPGGV

ZFYVE28

576

Q9HCC9
RRIQQAVESCPEEKG

ARHGEF28

1181

Q8N1W1
DPFVVDCSDKLGRVQ

ARID1A

1821

O14497
RPEKDGAATRVDAVC

MUC16

13381

Q8WXI7
LAIIAREGDCAPEEK

MAGEA3

206

P43357
NLKPGECLRVRGEVA

LGALS1

11

P09382
ECLRVRGEVAPDAKS

LGALS1

16

P09382
CNILKTEGVTVRRPD

GATM

131

P50440
RVCQAVQRAGDRPKS

FUT4

506

P22083
KAVAGRPVALECVAR

HMCN2

1636

Q8NDA2
VAIPHNRRKECGQED

KIF18A

751

Q8NI77
VECDPVRKEVSVRTG

KIF11

41

P52732
DIKNGRIEICNIEAP

LIPT1

301

Q9Y234
RDTACVKALRDIEPG

KMT5B

286

Q4FZB7
NVVDKSCPRGIIRVE

EDEM3

551

Q9BZQ6
LKVRPELRGDEQSCE

HPS5

566

Q9UPZ3
FRCLVDVVPVKNEDG

KCNH6

106

Q9H252
DEKPVDLTAGRRAVC

PCLO

2926

Q9Y6V0
VGKVPLCFVEREANE

MLH3

1301

Q9UHC1
VSDRIDREQICGKQP

PCDHGB2

86

Q9Y5G2
QPDRRDSIGVCAEKQ

CRLF3

326

Q8IUI8
GCPGEDVERAQKLRD

FAM74A3

61

Q4VXF1
DVERAQKLRDCPGED

FAM74A3

66

Q4VXF1
ELKGCPQEDVERVQR

FAM74A3

106

Q4VXF1
FEIICKRLRSEDGQP

KDM3B

1466

Q7LBC6
VDKDRKVCREPLVDG

LRP3

696

O75074
GKALPCIVDVRDEQQ

HSDL2

66

Q6YN16
GCEVAARAARRPEAV

KIF26A

1286

Q9ULI4
EALQLVKEGRVPCRT

MIGA2

321

Q7L4E1
ICVRKNLREVPDGIS

LRRC4C

61

Q9HCJ2
ELKRPSGDQVQVRRC

ENPEP

146

Q07075
APECGRCQRKILGEV

PDLIM5

476

Q96HC4
LEKVCRGNPADVTEA

PLPP2

146

O43688
KEARPVKNGCRGIDD

NTF3

196

P20783
CKGGPDEDAVERQRR

IQCF3

6

P0C7M6
VGRALQPVREKFSDC

ERVK-7

176

P63135
VGRALQPVREKFSDC

ERVK-6

176

Q9BXR3
ELKGCPQEDVERVQR

FAM74A7

106

A6NL05
REDAQPGAEVCRVRA

DCHS2

306

Q6V1P9
EDIVEVQGSPRCKIC

PRG3

96

Q9Y2Y8
AGPELQADCDQIVKR

PARP14

841

Q460N5
RCRPINATLAVEKEG

CGB2

26

Q6NT52
REKPEETCAAVRRGS

CTNNA3

861

Q9UI47
VDKCNLLEGEPREFV

EGFR

536

P00533
ERDLGQCDRFKPIRT

APOB

206

P04114
VTRRKGRCVEPETAN

DRAXIN

326

Q8NBI3
KCDQGQADPVVAVAR

HTT

941

P42858
RTVDPEQARGVLKCD

GRM6

731

O15303
PDENGVIAFDCRNRK

CACNA2D3

231

Q8IZS8
GGLEPERRDKCNRTV

CTTNBP2

936

Q8WZ74
EPIDLRCVKTRSEAG

CBX4

471

O00257
GQKRQLFDSDCVRDP

CCDC66

881

A2RUB6
EDAGKYVCRAVVPRV

KIRREL3

391

Q8IZU9
EVTPDDKRKACGRQL

GRK6

91

P43250
RDEKDGINRCLPDGQ

GRM1

131

Q13255
TGDPKRIDDVLCRVD

DNAH10

496

Q8IVF4
VIKVDFCADQPRIVD

CFAP47

201

Q6ZTR5
IPDCAGEVEKVLAAR

PKD1L1

2236

Q8TDX9
VPVDQVNRKDARACV

ATP4A

661

P20648
CKEAQPVVVIRAGDA

CTU2

31

Q2VPK5
CKEGDVLTPEQARVL

MRTO4

176

Q9UKD2
AQVDRPRVDIECAGK

OTOF

1151

Q9HC10
DGQIIKRVCGNERPA

PAMR1

191

Q6UXH9
RSQGPEIVEVEKGCR

MRC1

491

P22897
RVLQEGKARGCPEDA

IGF2R

521

P11717
ACPVVRVEGDNCEVK

IGF2R

1216

P11717
AAPREEQEKLGDICF

SYT5

231

O00445
LEVTCRRADAGEKPK

QARS1

661

P47897
ERIARKGEQCNIVPD

SPON1

406

Q9HCB6
DQEVQPGKRLRRVAC

SP4

611

Q02446
GAAEEEDARKRILCP

TRMT13

46

Q9NUP7
CEVSVTPEGVIKQRR

RAPGEF6

796

Q8TEU7
RLVDFGNIEDCVDPK

TDRD6

1601

O60522
QVVARQGRPVVICDK

GFPT1

626

Q06210
ERRICNAVSPDKDVD

MTHFD2

141

P13995
AVEFIVCRVKPADNE

TDRD12

996

Q587J7
SKAGETREAVPQCRV

SPATA31A7

946

Q8IWB4
GDCELDRVFIPVSKR

PKD1L3

851

Q7Z443
DPQKVARFQRLCGVE

SGPP1

16

Q9BX95
EKARAKCERDEAGNP

RNF227

106

A6NIN4
CICGELDQIDRKPRV

SHPRH

661

Q149N8
EAVRGDIFNQVVPRC

SIRT1

381

Q96EB6
KQVPGDEGREARLQC

WIZ

341

O95785
PQDKLEVREGAEIRC

PLB1

356

Q6P1J6
NPCEGDFRLQKLREA

OLFML2B

126

Q68BL8
PEEEDDIRNVIGRCK

OLFML2B

481

Q68BL8
SCEGVDLIDNPVIKR

AKR1E2

226

Q96JD6
DQDPRTAKEIALGRC

CILP

1081

O75339
DQSPRLAKEIAIGRC

CILP2

1066

Q8IUL8
GDIAQLCPARVEKRI

NCAPD3

861

P42695
IAFKRAEAVEPDGCV

C12orf76

21

Q8N812
PCGDVEKTRRAIRVF

CLEC16A

656

Q2KHT3
LTKRGRQVCADPSEE

CCL3L1

66

P16619
DPRSREVIRNACKAV

CLUH

691

O75153
VGRALQPVREKFSDC

ERVK-25

176

P63136
EKIPELARGDVCTAR

XIRP2

466

A4UGR9
SKAGETREAVPQCRV

SPATA31A3

946

Q5VYP0
LRAKGETCPRQVDNR

TMEM210

71

A6NLX4
PRAAGELEEAKCRRA

TULP4

1436

Q9NRJ4
TLLEQGKEPCVVARD

ZNF540

56

Q8NDQ6
GKEPCVVARDVTGRQ

ZNF540

61

Q8NDQ6
DAKGIETVRRDSCPA

REV3L

2851

O60673
SKAGETREAVPQCRV

SPATA31A1

946

Q5TZJ5
SKAGETREAVPQCRV

SPATA31A5

946

Q5VU36
VCERARQGCEPILIK

FRZB

111

Q92765
IACRQEGVPRTFKEI

GTF2B

166

Q00403
LAVDDDPEVRKNVCR

TNPO2

221

O14787
PLRVVATKDCEGERE

THEMIS2

346

Q5TEJ8
VGRALQPVREKFSDC

ERVK-10

176

P10266
DDCRKGRTQEDILVP

PSORS1C1

76

Q9UIG5
VGRALQPVREKFSDC

ERVK-11

176

Q9UQG0
KDIVPQEAEEFCRTG

TENM4

61

Q6N022
VTKRGQDVALRCDPI

TRBV7-6

31

A0A1B0GX31
VTKRGQDVTLRCDPI

TRBV7-7

31

A0A0K0K1E9
LAGDEEPEVRKNVCR

TNPO1

231

Q92973
DNCVIVGFVKPLAER

TOPORS

476

Q9NS56
KQPRVACDVEVDGVR

VPS13B

3931

Q7Z7G8
KIREEVPGRSDAQCR

SNAPC4

426

Q5SXM2
QREECVRKGRDPLTE

SEMA3G

101

Q9NS98
VRKGRDPLTECANFV

SEMA3G

106

Q9NS98
RGEVKPRTAECVTAQ

THSD7B

121

Q9C0I4
DRGALVAINPGDRKC

TPMT

151

P51580
ADLEEVVRVCPGFKA

TTC22

371

Q5TAA0
DAGDPAVEACENRRK

TCF25

531

Q9BQ70
VAKRGQDVALRCDPI

TRBV7-8

31

A0A1B0GX51
KTDVVCGPQDRLRAL

CD40

181

P25942
RCQEREFGLEIPQKE

ZNF175

96

Q9Y473
EKKPAGCLEERRDSQ

WNK3

496

Q9BYP7
EGAVLPRSAKELRCQ

CXCL8

21

P10145
KPVVGQCTIERLDRF

MYOF

1386

Q9NZM1