Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionnucleocytoplasmic carrier activity

NUP214 IPO4 IPO11 KPNB1 KPNA3

1.09e-05321865GO:0140142
GeneOntologyMolecularFunctionactin binding

BIN1 MYH9 NEBL MYO1E TRPM7 MYO9B MYH7B LRRK2 PTK2 GSN PDLIM3 TLN1 FSCN2 MACF1 FHDC1 SSH2

1.13e-0547918616GO:0003779
GeneOntologyMolecularFunctionnuclear import signal receptor activity

IPO4 IPO11 KPNB1 KPNA3

3.14e-05201864GO:0061608
GeneOntologyMolecularFunctionactin filament binding

BIN1 MYH9 NEBL MYO1E MYO9B MYH7B GSN TLN1 FSCN2 MACF1

5.53e-0522718610GO:0051015
GeneOntologyMolecularFunctionmolecular carrier activity

NASP NUP214 IPO4 CBLIF IPO11 KPNB1 KPNA3

6.86e-051081867GO:0140104
GeneOntologyMolecularFunctionrRNA (cytosine-N4-)-methyltransferase activity

METTL15P1 METTL15

8.63e-0521862GO:0071424
GeneOntologyMolecularFunctionnuclear localization sequence binding

NUP214 IPO4 KPNB1 KPNA3

1.08e-04271864GO:0008139
GeneOntologyMolecularFunctioncytoskeletal protein binding

BIN1 MYH9 NEBL MYO1E RTCB TRPM7 MYO9B MYH7B IFT81 CAPN2 LRRK2 LMTK2 DNM1L PTK2 GSN RMDN3 PDLIM3 TLN1 FSCN2 MACF1 FHDC1 SSH2 KPNB1

2.38e-04109918623GO:0008092
GeneOntologyMolecularFunctionclathrin binding

BIN1 CLTCL1 LRRK2 DNM1L SYT1

3.02e-04631865GO:0030276
GeneOntologyMolecularFunctionmicrofilament motor activity

MYH9 MYO1E MYO9B MYH7B

4.20e-04381864GO:0000146
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

PARP11 HK3 RPS6KA5 TRPM7 HYKK NTRK2 NTRK3 RPS6KA3 POLR2A MAP3K14 LRRK2 LMTK2 ACVR2B PTK2 PARP6 NEK1 ART3 PKLR FGGY PCYT1B

4.89e-0493818620GO:0016772
GeneOntologyMolecularFunctiontriplex DNA binding

DDX11 DDX11L8

5.11e-0441862GO:0045142
GeneOntologyMolecularFunctionneurotrophin receptor activity

NTRK2 NTRK3

8.47e-0451862GO:0005030
GeneOntologyMolecularFunctionGTPase activator activity

DOCK4 MYO9B LRRK2 DNM1L GIT2 RGS12 SRGAP3 ARHGAP28 NCKAP1L

1.25e-032791869GO:0005096
GeneOntologyMolecularFunctionrRNA (cytosine) methyltransferase activity

METTL15P1 METTL15

1.26e-0361862GO:0016434
GeneOntologyMolecularFunctionNAD+-protein-cysteine ADP-ribosyltransferase activity

PARP11 PARP6

1.26e-0361862GO:0140803
GeneOntologyMolecularFunctioncarboxylesterase activity

CES5A CES3

1.26e-0361862GO:0106435
GeneOntologyMolecularFunctionsignal sequence binding

NUP214 IPO4 KPNB1 KPNA3

1.29e-03511864GO:0005048
GeneOntologyCellularComponentactin cytoskeleton

BIN1 MYH9 PDCD6IP NEBL MYO1E MYO9B MYH7B CAPN2 KEAP1 PTK2 GSN TRMT10A PDLIM3 FSCN2 MACF1 FHDC1

6.43e-0557618716GO:0015629
DomainCarboxylesterase_B_AS

CEL CES5A CES3

5.16e-0581853IPR019826
DomainCARBOXYLESTERASE_B_1

CEL CES5A CES3

5.16e-0581853PS00122
DomainTPKR_C2

NTRK2 NTRK3

2.91e-0431852PF16920
DomainTyr_kinase_NGF_rcpt

NTRK2 NTRK3

2.91e-0431852IPR020777
DomainNTRK_C2

NTRK2 NTRK3

2.91e-0431852IPR031635
DomainCARBOXYLESTERASE_B_2

CEL CES5A CES3

3.21e-04141853PS00941
DomainIMPORTIN_B_NT

IPO4 IPO11 KPNB1

3.21e-04141853PS50166
DomainCOesterase

CEL CES5A CES3

3.21e-04141853PF00135
DomainCarbesteraseB

CEL CES5A CES3

3.21e-04141853IPR002018
Domain-

LRRK2 MROH5 HEATR1 IPO4 TRIP12 IPO11 ARMC6 KPNB1 KPNA3

3.80e-0422218591.25.10.10
DomainIBN_N

IPO4 IPO11 KPNB1

3.99e-04151853PF03810
DomainIBN_N

IPO4 IPO11 KPNB1

4.87e-04161853SM00913
DomainMyosin_head_motor_dom

MYH9 MYO1E MYO9B MYH7B

5.29e-04381854IPR001609
DomainMYOSIN_MOTOR

MYH9 MYO1E MYO9B MYH7B

5.29e-04381854PS51456
DomainMyosin_head

MYH9 MYO1E MYO9B MYH7B

5.29e-04381854PF00063
DomainMYSc

MYH9 MYO1E MYO9B MYH7B

5.29e-04381854SM00242
DomainTRPM_tetra

TRPM7 TRPM1

5.78e-0441852PF16519
DomainTRPM_tetra

TRPM7 TRPM1

5.78e-0441852IPR032415
DomainImportin-beta_N

IPO4 IPO11 KPNB1

5.87e-04171853IPR001494
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

MYH9 PDCD6IP RTCB LYPLA2 RPS6 CAPN2 PSMB1 NASP SMPD4 NUP214 KEAP1 CPOX IPO4 PLXNB2 CLCC1 GSN SACM1L RPL10A RMDN3 FASN LMAN1 TLN1 COG5 ALDH6A1 M6PR UBE2Z ALDH7A1 IPO11 ATP5F1B KPNB1

9.03e-1113671903032687490
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

PALD1 CLTCL1 PDCD6IP NUP85 MYO1E RTCB RPS6KA3 ECD PSMB1 MAP3K14 SMPD4 SAMHD1 HEATR1 IPO4 ECSIT CLCC1 GSN SACM1L FASN MDN1 TLN1 NFKB2 NUP210 NIP7 SERPINE1 COG5 IPO11 ATP5F1B KPNB1 KPNA3

3.12e-1014401903030833792
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

BIN1 MYH9 PDCD6IP NUP85 MYO1E RTCB RPS6 RPS6KA3 POLR2A CAPN2 PSMB1 NASP DNM1L SAMHD1 IPO4 PARP6 FASN TRMT10A UBE2H TLN1 GLS MACF1 COG5 ALDH7A1 GABPA IPO11 ATP5F1B KPNB1 KPNA3

1.75e-0914551902922863883
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

PALD1 MYH9 NEBL RTCB LYPLA2 RPS6 POLR2A ECD NASP TNRC6B DNM1L NUP214 HEATR1 KEAP1 RPL10A NEK1 FASN PDLIM3 TLN1 MACF1 BOD1L1 ATP5F1B KPNB1

2.03e-099341902333916271
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

MAN1A1 PDCD6IP NUP85 CAPN2 SAMHD1 NUP214 HEATR1 IPO4 ECSIT PLXNB2 TRIP12 CLCC1 SACM1L SEMA4C RMDN3 FASN LMAN1 TLN1 NUP210 XXYLT1 COG5 IPO11 KPNB1

2.38e-099421902331073040
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

MYH9 PDCD6IP NUP85 RTCB LYPLA2 RPS6 RPS6KA3 NASP SMPD4 DNM1L NUP214 HEATR1 KEAP1 IPO4 TRIP12 RPL10A FASN MDN1 LMAN1 NIP7 PKLR AQR GABPA IPO11 ATP5F1B ARMC6 KPNB1

3.81e-0913181902730463901
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

TRAF2 MYH9 PDCD6IP RTCB NSD2 RPS6 POLR2A PSMB1 NASP DNM1L SAMHD1 NUP214 HEATR1 CPOX IPO4 SACM1L RPL10A FASN MDN1 LMAN1 TLN1 GLS NUP210 BOD1L1 AQR ATP5F1B KPNB1

1.94e-0814251902730948266
Pubmed

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.

MYH9 CLTCL1 MYH7B CAPN2 PSMB1 TNRC6B SAMHD1 IPO4 ITIH2 GSN SACM1L RPL10A FASN MDN1 NUP210 PABPC1L ATP5F1B KPNB1

2.05e-086471901826618866
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

MYH9 CLTCL1 PDCD6IP RTCB RPS6 POLR2A PSMB1 VPS33A IPO4 GSN RPL10A RMDN3 FASN MDN1 PDLIM3 TLN1 MACF1 OSTF1 ATP5F1B KPNB1

2.21e-088071902030575818
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

MYH9 PDCD6IP RTCB NSD2 RPS6 POLR2A NUP214 HEATR1 IPO4 TRIP12 RPL10A FASN MDN1 TLN1 NUP210 MACF1 AQR KPNB1

2.36e-086531901822586326
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

TRAF2 MYH9 PDCD6IP RTCB MYO9B RPS6 POLR2A CAPN2 PSMB1 NUP214 HEATR1 IPO4 TRIP12 PTK2 RPL10A FASN MDN1 TLN1 NFKB2 GLS MACF1 AQR ALDH7A1 ATP5F1B KPNB1 KPNA3

2.76e-0813531902629467282
Pubmed

Comprehensive Proteomic Analysis of PGC7-Interacting Proteins.

TRAF2 NUP85 RTCB RPS6 IFT81 SMPD4 IPO4 RMDN3 PPP2R3C METTL15 SYCE1 KPNB1

6.98e-082871901228712289
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

PALD1 MYH9 PDCD6IP RPS6 TNRC6B DNM1L NUP214 KEAP1 CLCC1 SPICE1 RPL10A FASN LMAN1 TLN1 MACF1 BOD1L1 ATP5F1B KPNB1

7.95e-087081901839231216
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

PDCD6IP NUP85 POLR2A PSMB1 DNM1L SAMHD1 NUP214 HEATR1 IPO4 RPL10A FASN MDN1 TLN1 NUP210 IPO11 ATP5F1B KPNB1

9.56e-086381901733239621
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

CYP2A13 MYH9 CLTCL1 NUP85 NSD2 MYH7B RPS6 IFT81 ECD HEATR1 PPARA CPOX TRIP12 DDX11 FASN MDN1 GLS NIP7 SCN9A CES3 MACF1 BOD1L1 PABPC1L GABPA ATP5F1B KPNB1

9.69e-0814421902635575683
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

PDCD6IP NUP85 RTCB RPS6KA3 ECD CAPN2 PSMB1 DNM1L SAMHD1 NUP214 HEATR1 CPOX IPO4 GSN RPL10A RMDN3 FASN LMAN1 NUP210 ATP5F1B KPNB1

1.02e-079741902128675297
Pubmed

Defining the membrane proteome of NK cells.

MYH9 MAN1A1 CLTCL1 PDCD6IP NUP85 MYO9B RPS6 DNM1L HEATR1 IPO4 CLCC1 RPL10A FASN MDN1 LMAN1 NUP210 HSD11B1 COG5 M6PR AQR ATP5F1B KPNB1 NCKAP1L

1.22e-0711681902319946888
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

PDCD6IP NSD2 RPS6KA3 POLR2A DNM1L NUP214 HEATR1 GIT2 GSN FASN TLN1 KPNA3 NCKAP1L

1.48e-073701901322922362
Pubmed

Downregulation of TRAF2 mediates NIK-induced pancreatic cancer cell proliferation and tumorigenicity.

TRAF2 MAP3K14 NFKB2

1.60e-073190323301098
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

TRAF2 MYH9 PDCD6IP RTCB VPS33A DNM1L NUP214 KEAP1 SHOC2 PLXNB2 TRIP12 SACM1L FASN LMAN1 GLS NUP210 XXYLT1 MACF1 BOD1L1 AQR ALDH7A1 ARMC6 KPNB1 KPNA3

1.98e-0712971902433545068
Pubmed

High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.

TRAF2 NTRK2 CYP19A1 NTRK3 RPS6KA3 MAP3K14 PPARA ACVR2B AR STAR IFNAR2 OSTF1 HSD11B1

2.20e-073831901319453261
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

HK3 NUP85 MYO9B IFT81 POLR2A SMPD4 HEATR1 CPOX CPS1 TRIP12 SACM1L RMDN3 FASN MDN1 NFKB2 COG5 GABPA NOVA1 ARMC6

2.81e-078571901925609649
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

DOCK4 VPS37A CCDC186 RPS6 DNM1L IPO4 RMDN3 NEK1 MDN1 EXOC3L4 GLS SCAPER SSH2 GPT2 IPO11 DNAH11 RPAP2

2.82e-076891901736543142
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

PARP11 MYH9 PDCD6IP TRPM7 SLC22A23 NASP DNM1L NUP214 HEATR1 KEAP1 CPOX CLCC1 SACM1L SEMA4C RPL10A SNX14 FASN UBE2H SCAPER GMPR SSH2 COG5 PPP2R3C KPNA3

2.99e-0713271902432694731
Pubmed

Mutual regulation between OGT and XIAP to control colon cancer cell growth and invasion.

RTCB NASP ECSIT SHOC2 TRIP12 CLCC1 RPL10A LMAN1 GLS GPT2 ALDH6A1 ALDH7A1 GABPA ATP5F1B ARMC6 KPNB1 KPNA3

3.80e-077041901732994395
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

MYH9 PDCD6IP NEBL RTCB MYO9B RPS6 POLR2A PSMB1 TNRC6B SAMHD1 NUP214 TRIP12 SPICE1 SACM1L RPL10A FASN TLN1 GPT2 AQR ATP5F1B KPNB1 RPAP2 KPNA3

3.84e-0712471902327684187
Pubmed

Interferon induces NF-kappa B-inducing kinase/tumor necrosis factor receptor-associated factor-dependent NF-kappa B activation to promote cell survival.

TRAF2 MAP3K14 NFKB2

6.39e-074190316009713
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

BIN1 MYH9 NUP85 POLR2A VPS33A NUP214 HEATR1 IPO4 TRIP12 RPL10A SRGAP3 MACF1 BOD1L1 AQR

7.19e-074981901436634849
Pubmed

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.

MYH9 NUP85 PSMB1 TNRC6B SMPD4 HEATR1 CLCC1 RPL10A RMDN3 FASN LMAN1 NUP210 IPO11 ATP5F1B ARMC6 KPNB1

7.60e-076571901636180527
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

PDCD6IP NUP85 RTCB MYO9B RPS6 POLR2A NUP214 HEATR1 PLXNB2 TRIP12 GSN RPL10A FASN MDN1 TLN1 NUP210 MACF1 AQR ATP5F1B KPNB1

9.74e-0710241902024711643
Pubmed

FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.

MYH9 MYO1E RTCB MYO9B RPS6 POLR2A DNM1L SAMHD1 GIT2 TRIP12 RPL10A NFKB2 MACF1 ATP5F1B KPNA3

1.26e-066011901533658012
Pubmed

Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK.

TRAF2 MAP3K14 NFKB2

1.59e-065190318997794
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

BIN1 MYH9 PDCD6IP NTRK2 TNRC6B DNM1L GIT2 KEAP1 IPO4 PTK2 GSN SPICE1 MDN1 SRGAP3 SYT1 MACF1 SSH2 TMEM240 KPNB1

1.59e-069631901928671696
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

MYH9 PDCD6IP NUP85 MYO1E RTCB RPS6 ECD HEATR1 KEAP1 IPO4 TRIP12 ITIH2 GSN RPL10A FASN GLS NUP210 NIP7 SERPINE1 AQR ATP5F1B KPNB1

1.66e-0612571902236526897
Pubmed

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

NUP85 RTCB RPS6 POLR2A PSMB1 VPS33A NASP TNRC6B SMPD4 SAMHD1 KEAP1 CPOX IPO4 DDX11 RPL10A FASN MDN1 NUP210 ATP5F1B ARMC6 KPNB1 KPNA3

1.66e-0612571902237317656
Pubmed

SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.

MYH9 PDCD6IP RTCB MYH7B NASP DNM1L CPOX IPO4 TRIP12 SACM1L FASN LMAN1 TLN1 GLS IPO11 ATP5F1B KPNB1 KPNA3

1.78e-068781901837223481
Pubmed

Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6.

MYH9 PDCD6IP RTCB LYPLA2 RPS6 PSMB1 HEATR1 IPO4 RPL10A FASN MDN1 TLN1 NUP210 MACF1 ATP5F1B KPNB1

1.96e-067071901619738201
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

TRPM7 IFT81 ECD SMPD4 RTN4IP1 HEATR1 IPO4 ECSIT HSPA12B PLXNB2 BCS1L CLCC1 SPICE1 RPL10A MDN1 LMAN1 TLN1 GLS NUP210 NIP7 MACF1 M6PR AQR ATP5F1B

2.21e-0614871902433957083
Pubmed

The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.

PDCD6IP NUP85 MYO1E NSD2 CAPN2 DNM1L SAMHD1 IPO4 SACM1L MDN1 AQR ALDH7A1

2.35e-064001901235013556
Pubmed

Phase-separated nuclear bodies of nucleoporin fusions promote condensation of MLL1/CRM1 and rearrangement of 3D genome structure.

NUP85 NUP214 NUP210 KPNB1 KPNA3

2.60e-0640190537516964
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

AKAP6 DMGDH CLTCL1 TRPM7 NAT9 IFT81 PSMB1 VPS33A DNM1L SAMHD1 PPARA ACVR2B CPS1 BCS1L CLCC1 SPICE1 FAN1 RPL10A MDN1 UGT2A3 OSTF1 RPGR

2.62e-0612931902215342556
Pubmed

Evolutionary development of redundant nuclear localization signals in the mRNA export factor NXF1.

IPO4 IPO11 KPNB1

3.17e-066190321965294
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

MYH9 PDCD6IP MYO1E RTCB LYPLA2 RPS6 POLR2A ECD CAPN2 PSMB1 TNRC6B CPS1 GSN RPL10A FASN UBE2H TLN1 NIP7 MACF1 AQR ATP5F1B KPNB1 RPAP2

3.26e-0614151902328515276
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

PALD1 MYH9 TRPM7 LYPLA2 NASP SMPD4 DNM1L NUP214 CLCC1 RMDN3 FASN LMAN1 TLN1 KPNB1

3.33e-065681901437774976
Pubmed

TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.

TRAF2 VPS37A PDCD6IP RTCB MYO9B POLR2A PSMB1 TNRC6B COX11 SAMHD1 RPL10A FASN NFKB2 SCAPER ATP5F1B KPNB1 RPAP2 KPNA3

3.52e-069221901827609421
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

BIN1 MYH9 PDCD6IP MYO1E RTCB NAT9 RPS6 DNM1L GSN SACM1L RPL10A FASN SRGAP3 TLN1 SCAPER SYT1 MACF1 SSH2 ALDH7A1 ATP5F1B DNAH11 KPNB1 KPNA3

3.92e-0614311902337142655
Pubmed

Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.

TRAF2 MAN1A1 HK3 NUP85 CCDC186 NUP214 CLCC1 ALDH7A1 IPO11 PCYT1B

4.24e-062851901032838362
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

MYH9 MYO1E NSD2 TNRC6B NUP214 HEATR1 KEAP1 ECSIT CLCC1 GSN MDN1 LMAN1 NUP210 ALDH7A1 IPO11 KPNA3

4.45e-067541901633060197
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

DOCK4 PDCD6IP RTCB TRPM7 NTRK3 MAP3K14 LMTK2 DNM1L TRIP12 RGS12 SPICE1 NEK1 MDN1 MACF1 BOD1L1 SSH2 AQR

5.73e-068611901736931259
Pubmed

Global Interactome Mapping of Mitochondrial Intermembrane Space Proteases Identifies a Novel Function for HTRA2.

TRAF2 POLR2A CAPN2 RTN4IP1 NUP214 CPOX CPS1 ECSIT BCS1L MDN1 GLS OSTF1 GPT2

5.82e-065151901331617661
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

FAT4 MYH9 PDCD6IP TRPM7 CCDC186 RPS6 LRRK2 TNRC6B DNM1L IPO4 TRIP12 CLCC1 SEMA4C PKLR RPGR AP3S2

6.48e-067771901635844135
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

BEST1 VPS37A PDCD6IP HYKK NSD2 SLC22A23 TNRC6B PPARA ACVR2B AR CLCC1 PTK2 UBE2H NUP210 XXYLT1 MACF1 BOD1L1 OSTF1 GPT2 METTL15 FGGY PDZD2 RPAP2

7.49e-0614891902328611215
Pubmed

Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.

MYH9 LYPLA2 ECD NASP SMPD4 KEAP1 IPO4 CLCC1 FASN LMAN1 TLN1 KPNB1

7.59e-064491901231732153
Pubmed

Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.

PALD1 TRPM7 RPS6 SMPD4 PLXNB2 CLCC1 RPL10A RMDN3 MDN1 LMAN1 TLN1

7.71e-063751901132788342
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

PALD1 TRAF2 NUP85 TRPM7 PSMB1 COX11 SMPD4 DNM1L RTN4IP1 HEATR1 CPOX ECSIT PLXNB2 BCS1L CLCC1 RPL10A RMDN3 MDN1 LMAN1 GLS NIP7 METTL15 ATP5F1B

8.08e-0614961902332877691
Pubmed

Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.

TRPM7 RPS6KA3 IFT81 POLR2A DNM1L NUP214 SHOC2 SACM1L NEK1 LMAN1 IPO11 RPAP2 KPNA3

8.40e-065331901325544563
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

AKAP6 HK3 PDCD6IP RPS6KA3 LMTK2 NASP DNM1L RTN4IP1 HEATR1 TRIP12 EXOC3L4 PGAP1 SYT1 MACF1 BOD1L1 COG5 SLX4 KPNA3 NCKAP1L

8.68e-0610841901911544199
Pubmed

TrkB and TrkC signaling are required for maturation and synaptogenesis of hippocampal connections.

NTRK2 NTRK3 SYT1

8.81e-06819039736654
Pubmed

MYH9-dependent polarization of ATG9B promotes colorectal cancer metastasis by accelerating focal adhesion assembly.

MYH9 FASN TLN1

8.81e-068190334131310
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

MYH9 PDCD6IP RTCB RPS6 POLR2A NASP HEATR1 IPO4 TRIP12 RPL10A FASN MDN1 NFKB2 GLS NIP7 BOD1L1 ATP5F1B KPNB1

9.15e-069891901836424410
Pubmed

Deubiquitinating enzyme PSMD14 promotes tumor metastasis through stabilizing SNAIL in human esophageal squamous cell carcinoma.

DOCK4 MYH9 CLTCL1 RTCB RPS6 SAMHD1 IPO4 FASN IPO11 ATP5F1B KPNB1

9.39e-063831901129331416
Pubmed

ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ.

MYH9 RPS6 PSMB1 SAMHD1 NUP214 HEATR1 IPO4 TRIP12 RPL10A FASN MDN1 ATP5F1B ARMC6 RPAP2

9.65e-066241901433729478
Pubmed

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.

NASP COX11 IPO4 TRIP12 RGS12 TLN1 MACF1 ARHGAP28 PPP2R3C KPNB1

1.23e-053221901026514267
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

MYH9 RPS6 POLR2A ECD NASP NUP214 HEATR1 FASN TLN1

1.27e-05256190933397691
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

TRAF2 RPS6KA5 RPS6KA3 POLR2A CAPN2 DNM1L KEAP1 PLXNB2 PTK2 SACM1L SEMA4C NEK1 CES3 SSH2 DNAH11

1.30e-057301901534857952
Pubmed

Sex chromosome complement determines sex differences in aromatase expression and regulation in the stria terminalis and anterior amygdala of the developing mouse brain.

CYP19A1 AR STAR

1.32e-059190326231585
Pubmed

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

DMGDH HK3 COX11 RTN4IP1 CPOX CPS1 ECSIT BCS1L STAR RPL10A RMDN3 FASN CROT GLS GPT2 ALDH6A1 ALDH7A1

1.47e-059261901720877624
Pubmed

Identification of different proteins binding to Na, K-ATPase α1 in LPS-induced ARDS cell model by proteomic analysis.

MYH9 POLR2A CPS1 TRIP12 FASN TLN1 NFKB2

1.52e-05144190735681168
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

PDCD6IP RPS6KA3 POLR2A DNM1L SAMHD1 NUP214 FASN MDN1 TLN1 BOD1L1

1.60e-053321901032786267
Pubmed

Transferrin Receptor Protein 1 Cooperates with mGluR2 To Mediate the Internalization of Rabies Virus and SARS-CoV-2.

RPS6 PSMB1 HEATR1 TRIP12 RPL10A MDN1 LMAN1 BOD1L1 ATP5F1B KPNB1

1.64e-053331901036779763
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DOCK4 PALD1 TNRC6B NUP214 SACM1L SRGAP3 TLN1 MACF1 BOD1L1 AQR PDZD2

1.65e-054071901112693553
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

MYH9 CLTCL1 POLR2A HEATR1 PTK2 FASN NUP210 AQR

1.66e-05202190824639526
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

DOCK4 BIN1 MYH9 PDCD6IP RPS6 NTRK2 CAPN2 VPS33A LMTK2 TNRC6B SHOC2 SACM1L SRGAP3 GLS SYT1 MACF1 ALDH6A1 ATP5F1B ARMC6

1.73e-0511391901936417873
Pubmed

ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells.

TRAF2 MYH9 MYO1E MYH7B SAMHD1 GSN FASN LMAN1 ATP5F1B

1.83e-05268190933024031
Pubmed

Proteomic analysis of α4β1 integrin adhesion complexes reveals α-subunit-dependent protein recruitment.

MYH9 PDCD6IP LYPLA2 RPS6 PSMB1 NUP214 HEATR1 RPL10A TLN1 NUP210 ATP5F1B KPNB1

1.84e-054911901222623428
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

MYH9 RTCB RPS6 HEATR1 CPS1 CBLB TRIP12 GSN RPL10A FASN MDN1 NUP210 NIP7 AQR ATP5F1B KPNB1

1.87e-058471901635850772
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

COL6A6 NAT9 IFT81 POLR2A NASP NUP214 TRIP12 RGS12 SNX14 MDN1 SCN9A IPO11

2.08e-054971901236774506
Pubmed

Mitochondrial protein interactome elucidated by chemical cross-linking mass spectrometry.

DNM1L CPOX CPS1 BCS1L RMDN3 CROT GLS GPT2 ALDH6A1 ATP5F1B

2.12e-053431901028130547
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

MYH9 PDCD6IP RTCB VPS33A DNM1L SHOC2 TRIP12 FASN MDN1 TLN1 MACF1 AQR KPNB1

2.12e-055821901320467437
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

MYH9 PDCD6IP CPS1 FASN MDN1 TLN1 IPO11 ATP5F1B KPNB1 NCKAP1L

2.17e-053441901030333137
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

CAPN2 VPS33A DNM1L NUP214 IPO4 MDN1 NIP7 MACF1 BOD1L1

2.73e-05282190923667531
Pubmed

Genes related to sex steroids, neural growth, and social-emotional behavior are associated with autistic traits, empathy, and Asperger syndrome.

NTRK2 CYP19A1 NTRK3 AR HSD11B1

2.92e-0565190519598235
Pubmed

Gelsolin dysfunction causes photoreceptor loss in induced pluripotent cell and animal retinitis pigmentosa models.

GSN RPGR

2.97e-052190228814713
Pubmed

Interaction of focal adhesion kinase with cytoskeletal protein talin.

PTK2 TLN1

2.97e-05219027622520
Pubmed

PPARalpha deficiency does not modify age dependency but prevents high fat diet increase in plasma PAI-1 as well as insulin resistance.

PPARA SERPINE1

2.97e-052190215116271
Pubmed

Polymorphisms in the CYP19 and AR genes--relation to bone mass and longitudinal bone changes in postmenopausal women with or without hormone replacement therapy: The Danish Osteoporosis Prevention Study.

CYP19A1 AR

2.97e-052190214517714
Pubmed

Elevated androgens and prolactin in aromatase-deficient mice cause enlargement, but not malignancy, of the prostate gland.

CYP19A1 AR

2.97e-052190211356695
Pubmed

METTL15 interacts with the assembly intermediate of murine mitochondrial small ribosomal subunit to form m4C840 12S rRNA residue.

METTL15P1 METTL15

2.97e-052190232573735
Pubmed

TrkB but not trkC receptors are necessary for postnatal maintenance of hippocampal spines.

NTRK2 NTRK3

2.97e-052190217442456
Pubmed

Lasp2 enhances tumor invasion via facilitating phosphorylation of FAK and predicts poor overall survival of non-small cell lung cancer patients.

NEBL PTK2

2.97e-052190228667800
Pubmed

ERK regulates calpain 2-induced androgen receptor proteolysis in CWR22 relapsed prostate tumor cell lines.

CAPN2 AR

2.97e-052190219946123
Pubmed

Selective activation and down-regulation of Trk receptors by neurotrophins in human neurons co-expressing TrkB and TrkC.

NTRK2 NTRK3

2.97e-052190235536742
Pubmed

Inhibition of prostate cancer cell growth by second-site androgen receptor antagonists.

AR GSN

2.97e-052190219574450
Pubmed

Molecular cloning of the oncofetal isoform of the human pancreatic bile salt-dependent lipase.

CEL LMAN1

2.97e-05219029774442
Pubmed

Collagen remodeling by phagocytosis is determined by collagen substrate topology and calcium-dependent interactions of gelsolin with nonmuscle myosin IIA in cell adhesions.

MYH9 GSN

2.97e-052190223325791
Pubmed

Discovery and characterization of targetable NTRK point mutations in hematologic neoplasms.

NTRK2 NTRK3

2.97e-052190232315394
Pubmed

BIN1/M-Amphiphysin2 induces clustering of phosphoinositides to recruit its downstream partner dynamin.

BIN1 DNM1L

2.97e-052190225487648
Pubmed

Lack of TrkB and TrkC signaling alters the synaptogenesis and maturation of mossy fiber terminals in the hippocampus.

NTRK2 NTRK3

2.97e-052190215726425
Pubmed

Haematopoietic focal adhesion kinase deficiency alters haematopoietic homeostasis to drive tumour metastasis.

POLR2A PTK2

2.97e-052190225270220
Pubmed

Inhibition by fibrates of plasminogen activator inhibitor type-1 expression in human adipocytes and preadipocytes.

PPARA SERPINE1

2.97e-052190219492148
InteractionEED interactions

MYH9 MAN1A1 PDCD6IP NUP85 MYO1E RTCB NSD2 RPS6 POLR2A CAPN2 NDST4 SMPD4 DNM1L NUP214 HEATR1 IPO4 CBLB PLXNB2 TRIP12 AR GSN RPL10A FASN TLN1 NFKB2 NUP210 NIP7 MACF1 UBE2Z AQR ATP5F1B KPNB1

2.25e-06144518332int:EED
InteractionNRIP1 interactions

AKAP6 TRAF2 POLR2A VPS33A PPARA TRIP12 AR MACF1 KPNB1 KPNA3

3.61e-0617018310int:NRIP1
InteractionAPPL1 interactions

TRAF2 BIN1 RTCB NTRK2 NTRK3 CBLB AR PHAF1 LMAN1 SCAPER

6.62e-0618218310int:APPL1
InteractionNUP155 interactions

PDCD6IP NUP85 TRPM7 NTRK3 TNRC6B SMPD4 DNM1L NUP214 CLCC1 RMDN3 LMAN1 UBE2H NUP210 SLX4 IPO11 KPNB1

7.76e-0647718316int:NUP155
InteractionGSK3B interactions

TRAF2 MYH9 PDCD6IP NAT9 ECD CAPN2 LRRK2 TNRC6B DNM1L SAMHD1 KEAP1 TRIP12 AR PTK2 GSN SPICE1 NEK1 FASN NFKB2 MACF1 SLX4 KPNB1

1.37e-0586818322int:GSK3B
InteractionKCNA3 interactions

PALD1 MYH9 PDCD6IP MYH7B RPS6 NTRK2 LRRK2 TNRC6B DNM1L NUP214 KEAP1 CLCC1 SPICE1 RPL10A FASN LMAN1 TLN1 MACF1 BOD1L1 TRPM1 ATP5F1B KPNB1

1.44e-0587118322int:KCNA3
InteractionSTIP1 interactions

PDCD6IP NUP85 RPS6KA3 POLR2A PSMB1 LRRK2 NASP DNM1L SAMHD1 NUP214 HEATR1 IPO4 AR PTK2 RPL10A FASN MDN1 LMAN1 UBE2H TLN1 NUP210 IPO11 ATP5F1B KPNB1

1.47e-05100618324int:STIP1
InteractionLMBR1L interactions

MAN1A1 PDCD6IP NUP85 CAPN2 SAMHD1 NUP214 HEATR1 IPO4 ECSIT PLXNB2 TRIP12 CLCC1 SACM1L SEMA4C RMDN3 FASN LMAN1 TLN1 NUP210 XXYLT1 COG5 IPO11 KPNB1

1.67e-0594618323int:LMBR1L
InteractionOGT interactions

RTCB NSD2 NASP NUP214 ECSIT SHOC2 TRIP12 AR CLCC1 RPL10A LMAN1 UBE2H GLS BOD1L1 GPT2 ALDH6A1 SLX4 ALDH7A1 GABPA ATP5F1B ARMC6 KPNB1 KPNA3

1.78e-0595018323int:OGT
InteractionECT2 interactions

MYH9 CLTCL1 PDCD6IP MYO1E RPS6 CAPN2 TNRC6B HEATR1 CPS1 TRIP12 GSN RPL10A FASN EXOC3L4 NUP210 NIP7 MACF1 BOD1L1 PABPC1L PDZD2 KPNB1 RPAP2

1.90e-0588718322int:ECT2
InteractionMAPRE1 interactions

TRAF2 NUP85 MYO1E RPS6 PSMB1 LRRK2 SMPD4 NUP214 HSPA12B SHOC2 RPL10A UBE2H NUP210 MACF1 KPNB1 KPNA3

1.95e-0551418316int:MAPRE1
InteractionNR2C2 interactions

TRAF2 MYH9 PDCD6IP NUP85 RTCB LYPLA2 RPS6 RPS6KA3 NASP SMPD4 DNM1L NUP214 HEATR1 KEAP1 IPO4 TRIP12 AR RPL10A FASN MDN1 LMAN1 NIP7 PKLR AQR GABPA IPO11 ATP5F1B ARMC6 KPNB1

2.63e-05140318329int:NR2C2
InteractionNAA40 interactions

PALD1 MYH9 NEBL RTCB LYPLA2 RPS6 POLR2A ECD NASP TNRC6B DNM1L NUP214 HEATR1 KEAP1 RPL10A NEK1 FASN PDLIM3 TLN1 MACF1 BOD1L1 ATP5F1B KPNB1

2.81e-0597818323int:NAA40
InteractionPLCG1 interactions

MYH9 TRPM7 NTRK2 NTRK3 PLXNB2 AR PTK2 GSN FASN UBE2H TLN1

3.09e-0526418311int:PLCG1
InteractionFOXP3 interactions

PDCD6IP NSD2 RPS6KA3 POLR2A DNM1L NUP214 HEATR1 GIT2 GSN FASN TLN1 NOVA1 KPNA3 NCKAP1L

4.25e-0543218314int:FOXP3
InteractionOBSL1 interactions

NUP85 RTCB RPS6 POLR2A PSMB1 NUP214 HEATR1 CBLB TRIP12 AR GSN RPL10A FASN MDN1 UBE2H TLN1 NUP210 MACF1 AQR ATP5F1B KPNB1

7.41e-0590218321int:OBSL1
InteractionFOXL1 interactions

HK3 MYO9B SMPD4 HEATR1 RMDN3 FASN MDN1 COG5 NOVA1

7.86e-051961839int:FOXL1
InteractionUGT2A2 interactions

UGT2A2 UGT2A3

8.20e-0521832int:UGT2A2
InteractionRAC1 interactions

DOCK4 PALD1 BIN1 MYH9 MYO1E TRPM7 RPS6 RPS6KA3 LRRK2 GIT2 IPO4 PLXNB2 ITGB8 CLCC1 PTK2 FASN MDN1 LMAN1 UBE2H SRGAP3 MACF1 COG5 KPNB1

1.00e-04106318323int:RAC1
InteractionNUMA1 interactions

NUP85 MYO1E NSD2 LYPLA2 NUP214 KEAP1 TRIP12 AR UBE2H TLN1 NUP210 MACF1 SLX4 KPNB1

1.02e-0446918314int:NUMA1
InteractionAGR2 interactions

TRAF2 MYH9 CLTCL1 PDCD6IP RTCB RPS6 POLR2A PSMB1 VPS33A IPO4 GSN RPL10A RMDN3 FASN MDN1 PDLIM3 TLN1 MACF1 OSTF1 ATP5F1B KPNB1

1.21e-0493418321int:AGR2
InteractionRANBP1 interactions

NUP85 LRRK2 DNM1L NUP214 IPO4 UBE2H NUP210 KPNB1 KPNA3

1.38e-042111839int:RANBP1
InteractionKPNB1 interactions

NUP85 RPS6 MAP3K14 SMPD4 DNM1L SAMHD1 NUP214 IPO4 FAN1 UBE2H NUP210 SLX4 IPO11 KPNB1 KPNA3

1.39e-0454418315int:KPNB1
InteractionNUDCD2 interactions

MYH9 MYO1E RPS6 CYP19A1 CPS1 PTK2 LMAN1 UBE2H NUP210 OSTF1 RPGR ATP5F1B KPNB1

1.39e-0442418313int:NUDCD2
InteractionMTNR1A interactions

NASP COX11 TRIP12 RGS12 TLN1 ARHGAP28 PPP2R3C KPNB1

1.41e-041661838int:MTNR1A
InteractionSSB interactions

MYH9 RPS6 LRRK2 DNM1L CPOX AR FAN1 RPL10A FASN UBE2H TLN1 MACF1 ARMC6 KPNB1

1.42e-0448418314int:SSB
InteractionSIRT7 interactions

MYH9 PDCD6IP RTCB NSD2 RPS6 POLR2A NUP214 HEATR1 IPO4 TRIP12 RPL10A FASN MDN1 TLN1 NUP210 MACF1 AQR KPNB1

1.55e-0474418318int:SIRT7
GeneFamilyArmadillo repeat containing|Importins

IPO4 IPO11 KPNB1 KPNA3

7.44e-06181314596
GeneFamilyCarboxylesterases

CES5A CES3

5.14e-0451312461
CoexpressionZHENG_BOUND_BY_FOXP3

PARP11 MAN1A1 HK3 TNRC6B SAMHD1 CPOX CR1L CBLB IFNAR2 SNX14 UBE2H PGAP1 XXYLT1 MACF1 SSH2 AQR

7.35e-0749818916M1741
CoexpressionZHENG_BOUND_BY_FOXP3

PARP11 MAN1A1 HK3 TNRC6B SAMHD1 CPOX CR1L CBLB IFNAR2 SNX14 UBE2H PGAP1 XXYLT1 MACF1 SSH2 AQR

9.30e-0750718916MM1030
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

BIN1 MYH9 MAN1A1 RPS6KA5 MYO9B RPS6KA3 CAPN2 TNRC6B GIT2 CBLB TRIP12 VSIR SACM1L IFNAR2 RPL10A SRGAP3 TLN1 GLS NUP210 MACF1 BOD1L1 LTB OSTF1 SSH2 GABPA KPNB1 NCKAP1L

9.81e-06149218927M40023
CoexpressionMARSON_BOUND_BY_FOXP3_UNSTIMULATED

SLC9A9 PDCD6IP MYO1E RPS6KA5 NAT9 WDR31 RPS6KA3 POLR2A MAP3K14 AMDHD1 NASP COX11 RTN4IP1 CR1L CLCC1 VSIR PTK2 SACM1L UBE2H FSCN2 OSTF1 ARMC6 KPNB1 KPNA3

1.07e-05123918924M1743
CoexpressionGSE5503_LIVER_DC_VS_PLN_DC_ACTIVATED_ALLOGENIC_TCELL_UP

BEST1 CEL RPS6 IPO4 HSPA12B RGS12 TLN1 SYT1 ALDH7A1

1.51e-051991899M6992
CoexpressionGSE27786_LIN_NEG_VS_NKTCELL_DN

MYO1E MYO9B GIT2 CR1L FASN DPF3 SLX4 AQR RPAP2

1.57e-052001899M4788
CoexpressionGSE29164_DAY3_VS_DAY7_CD8_TCELL_TREATED_MELANOMA_UP

AKAP6 TRAF2 MYO9B RGS12 DDX11 SCAPER BANK1 SLX4 PCYT1B

1.57e-052001899M8488
CoexpressionMARSON_BOUND_BY_FOXP3_UNSTIMULATED

SLC9A9 PDCD6IP MYO1E RPS6KA5 NAT9 WDR31 RPS6KA3 POLR2A MAP3K14 AMDHD1 NASP COX11 RTN4IP1 CR1L CLCC1 VSIR PTK2 SACM1L UBE2H FSCN2 OSTF1 ARMC6 KPNB1 KPNA3

1.75e-05127718924MM1032
CoexpressionKONDO_EZH2_TARGETS

DOCK4 NEBL CYP19A1 TNRC6B LMAN1 DPF3 NIP7 SERPINE1 CXCL5

4.55e-052291899M5301
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

AKAP6 DOCK4 CELF6 COL6A6 CCDC186 NTRK3 LRRK2 ACVR2B ZNF385D MDN1 SRGAP3 PGAP1 SCN9A SYT1 BOD1L1 SSH2 CXCL5 MGAT4C GPR176 UBE2Z NOVA1

5.26e-05110618921M39071
CoexpressionPARENT_MTOR_SIGNALING_UP

BIN1 MYO9B LYPLA2 CYP19A1 NASP TNRC6B GIT2 PPARA CBLB SYT1 GMPR RPGR ALDH7A1 NCKAP1L

6.84e-0556718914M16909
CoexpressionGSE5099_CLASSICAL_M1_VS_ALTERNATIVE_M2_MACROPHAGE_UP

PARP11 BIN1 RPS6KA3 CAPN2 SAMHD1 CBLB SEMA4C PGAP1

8.65e-051941898M6595
CoexpressionGSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_4H_CD4_TCELL_UP

SLC9A9 BIN1 CES5A HYKK SLC22A23 TNRC6B SAMHD1 ST7L

8.65e-051941898M4187
CoexpressionGSE25123_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_UP

FAT4 NSD2 ECD CAPN2 VPS33A NUP214 SNX14 LMAN1

1.03e-041991898M7967
CoexpressionGSE9988_ANTI_TREM1_VS_CTRL_TREATED_MONOCYTES_DN

RTCB MAP3K14 NUP214 GIT2 PLXNB2 PHAF1 BOD1L1 NCKAP1L

1.07e-042001898M5851
CoexpressionGSE17186_BLOOD_VS_CORD_BLOOD_CD21HIGH_TRANSITIONAL_BCELL_UP

HK3 SEMA4C IFNAR2 NFKB2 PPP2R3C M6PR KPNA3 NCKAP1L

1.07e-042001898M7185
CoexpressionGSE25088_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_UP

PDCD6IP RPS6KA5 CAPN2 RTN4IP1 PLXNB2 SSH2 UBE2Z BANK1

1.07e-042001898M7981
CoexpressionGSE16385_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_UP

RPS6KA5 MYO9B MAP3K14 PTK2 SPICE1 CBLIF SCAPER NCKAP1L

1.07e-042001898M7990
CoexpressionHU_FETAL_RETINA_MICROGLIA

DOCK4 PALD1 BIN1 MYH9 MYO9B SAMHD1 VSIR GSN TLN1 OSTF1 NCKAP1L

1.11e-0438218911M39266
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

AKAP6 MYH9 MYO1E NTRK3 ZNF385D GLS SERPINE1 MACF1 ARHGAP28 GPR176

9.31e-09189190106b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DOCK4 SLC9A9 FAT4 COL6A6 ZNF385D SRGAP3 MACF1 ARHGAP28 OSTF1

1.75e-0719619091450cb69c5bf469e97c03bf1890f6f7c54165b8a
ToppCellLV|World / Chamber and Cluster_Paper

AKAP6 NEBL TRPM7 MYH7B ART3 DPF3 MGAT4C PDZD2

1.10e-0618019085ac6f485a58bb29462fec02dfbe8eb70864eafe3
ToppCellfacs-Spleen|facs / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BIN1 MAN1A1 MYO1E RPS6 RPL10A PGAP1 LTB BANK1

1.24e-061831908d8e87234d2fc2059536ed456993ab0557d118361
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

DOCK4 DMGDH FAT4 NTRK2 SAMHD1 AR NEK1 HSD11B1

1.29e-06184190867164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellfacs-Spleen-nan-3m-Lymphocytic-CD79a_B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAN1A1 MYO1E LRRK2 GSN PGAP1 MACF1 BANK1 NCKAP1L

1.46e-061871908b51af2824e65734f333b1325117f4a2e88b17c23
ToppCellfacs-Spleen-nan-3m-Lymphocytic-B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAN1A1 MYO1E LRRK2 GSN PGAP1 MACF1 BANK1 NCKAP1L

1.46e-0618719083ca3954f45f167e98a230f2847f0582d74fcd32e
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

AKAP6 MYO1E NTRK3 PDLIM3 GLS MACF1 ARHGAP28 GPR176

1.52e-06188190834e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellControl-Myeloid-TRAM2|Myeloid / Condition, Lineage and Cell class

CAPN2 ITGB8 NFKB2 ANKDD1A SERPINE1 GMPR UBE2Z PDZD2

1.78e-061921908571fd71dad361a8b6c1bf9ad7184a89b3fbec667
ToppCellRV-02._Fibroblast_II|RV / Chamber and Cluster_Paper

SLC9A9 MAN1A1 SAMHD1 CBLB GSN SERPINE1 SSH2 NOVA1

1.92e-06194190811c79a8c56ece42713b04b321982e41e239f07a5
ToppCellControl-Myeloid-TRAM2|Control / Condition, Lineage and Cell class

CAPN2 ITGB8 NFKB2 SERPINE1 GMPR CXCL5 UBE2Z PDZD2

1.92e-061941908d951dd1274d3ff1ac30671ec4153a4a8bc97b53f
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SLC9A9 FAT4 COL6A6 CBLB ZNF385D MACF1 ARHGAP28 OSTF1

2.15e-06197190811a4c417f035e554431a8f03be13b5eefa3530c0
ToppCellSepsis-Bac-SEP-Lymphocyte-T/NK-CD8+_Tcm|Bac-SEP / Disease, condition lineage and cell class

BIN1 LYPLA2 RPS6 CROT MDN1 PGAP1 KCNJ13 LTB

2.24e-06198190884a07dea22b7771b34118729607b48c2d75df870
ToppCelldroplet-Liver-nan-3m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMGDH CPS1 ITIH2 CROT UGT2A3 CES3 ALDH6A1

3.96e-061511907cc9632b58522e2ba3ad36a0b8d37c7c9c8b636c4
ToppCelldroplet-Liver-nan-3m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMGDH CPS1 ITIH2 CROT UGT2A3 CES3 ALDH6A1

3.96e-0615119077758cfbe8dca849c90bd6e8bc63310e53beeb8fd
ToppCelldroplet-Liver-nan-3m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMGDH CPS1 ITIH2 CROT UGT2A3 CES3 ALDH6A1

3.96e-061511907b4a0546c1573b4b2290890307f2a5daf3a7cbb37
ToppCelldroplet-Liver-nan-3m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMGDH CPS1 ITIH2 CROT UGT2A3 CES3 ALDH6A1

4.14e-061521907faa92f7c5a6db9f1eb7d8ec930ba7c8ed9fd1bf1
ToppCelldroplet-Liver-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMGDH CPS1 ITIH2 CROT UGT2A3 CES3 ALDH6A1

4.14e-0615219071febeeb7376e34b9f86c81b2cb1314ee12408864
ToppCellfacs-Liver-Hepatocytes|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMGDH CPS1 ITIH2 UGT2A3 CES3 GPT2 ALDH6A1

4.91e-061561907e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

AKAP6 NTRK2 PPARA MDN1 SCAPER ALDH6A1 MGAT4C

6.04e-061611907347edb0de10850b7d16c40945751033289289c9b
ToppCelldroplet-Mammary_Gland-nan-21m-Epithelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PARP11 MYO9B IPO4 ITIH2 NEK1 PDLIM3 FGGY

7.10e-0616519077c771f22b58989572c939ed127e637ec28dc0dca
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Reln_Tac1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DOCK4 AMN MYO1E CPS1 PDLIM3 SCN9A GPR176

7.10e-061651907d8df50f5a3b646e8ea13739fdc65ce6f39b4d4d2
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Hematologic-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BEST1 HK3 SRGAP3 LTB HSD11B1 GPT2 CXCL5

8.30e-06169190715a9183c838cc6384d7f5dfeae3d30602964c9b3
ToppCellSmart-seq2-blood_(Smart-seq2)|Smart-seq2 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HK3 LRRK2 SAMHD1 PLXNB2 VSIR GMPR LTB

8.30e-0616919070ee74cc97a2db9cc16dc73424f74747afe13af90
ToppCellCOVID-19-Heart-Neuronal|Heart / Disease (COVID-19 only), tissue and cell type

MYO1E SLC22A23 CYP19A1 SAMHD1 ITGB8 SCN9A RPGR

9.67e-0617319076fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCelldroplet-Marrow-nan-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK3 LRRK2 VSIR GSN PABPC1L LTB OSTF1

1.00e-0517419074b749ac9f05776c0c56b74daca833bd0b5704299
ToppCellE12.5-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SLC9A9 NTRK2 NTRK3 PTK2 ART3 SERPINE1 GPR176

1.12e-0517719075cdf413f82376a95467322b16d10b0d1e7557e2d
ToppCellfacs-Lung-EPCAM-3m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC22A23 MAP3K14 CBLB ITGB8 NFKB2 SCAPER KPNA3

1.16e-0517819070b456ac768e026c3ecd5a9a4f43d6f126e7685a1
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BIN1 AMN PPARA CES3 GPT2 ALDH6A1 PDZD2

1.21e-05179190778fae47ec9bff4e0159a86a281e831d7f8ee925a
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BIN1 MAN1A1 MYO1E RPS6 RPL10A LTB BANK1

1.25e-051801907243622eee35d38748e945677ff115616e763e3b4
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BIN1 MAN1A1 MYO1E RPS6 RPL10A LTB BANK1

1.25e-0518019073a8d9a71efe113d1df3933902a625c0a56812074
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC9A9 ACVR2B ART3 HSD11B1 METTL15 PCYT1B PDZD2

1.30e-051811907274c0b768925cd5804483303f8c5ebd17a534c41
ToppCelldroplet-Thymus-nan-24m-Myeloid-nan|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BIN1 MYO1E LRRK2 SAMHD1 NFKB2 LTB BANK1

1.30e-0518119072a3092fbadd18967199f1203c11f0dd956417254
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DMGDH NEBL LRRK2 ITGB8 RGS12 SRGAP3 PDZD2

1.34e-051821907eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCelldroplet-Spleen-nan-18m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAN1A1 MYO1E LRRK2 RPL10A MACF1 LTB BANK1

1.39e-05183190728cbf909424f3be4491d49832f0aca0386560814
ToppCellMild/Remission-B_intermediate-10|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

MYO9B LRRK2 CBLB PTK2 TLN1 SYT1 MACF1

1.39e-051831907278064c9f0582463b83bf156d34e77f60187613b
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAN1A1 MYO1E LRRK2 RPL10A MACF1 LTB BANK1

1.39e-0518319073fa608aa6b119869ec3280dc388dfee57160e63a
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DMGDH AMN FADS6 DPF3 UGT2A3 ALDH6A1 PCYT1B

1.39e-051831907d73cac83cde82665f110baad7cf28db75f9ffe52
ToppCellRA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

AKAP6 MYO1E NTRK3 PDLIM3 GLS ARHGAP28 GPR176

1.39e-051831907cae2ee08f985a6f005b4b8e959e465350315156a
ToppCellPBMC-Mild-cDC_9|Mild / Compartment, Disease Groups and Clusters

MYO1E SAMHD1 HEATR1 ACVR2B CR1L ZNF385D CES3

1.44e-0518419072e0c9a2c40c892a2d435eafb31f1f838de9baf15
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL6A6 NTRK2 NTRK3 ZNF385D PDLIM3 HSD11B1 MGAT4C

1.44e-0518419074d4d8f3f44c67d74c57e7af7b7c158f0157b2f49
ToppCelldroplet-Spleen|droplet / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BIN1 MAN1A1 MYO1E RPS6 RPL10A LTB BANK1

1.49e-051851907392c3130c79f7a938b73461c9dded803bb5c5785
ToppCellFetal_29-31_weeks-Immune-enucleated_erythrocyte-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MAN1A1 SLC22A23 CPOX CR1L DPF3 GMPR FHDC1

1.49e-051851907c4bf3ac684c1a8876b51f7af4d3a62dc47e961ee
ToppCellFetal_29-31_weeks-Immune-enucleated_erythrocyte-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MAN1A1 SLC22A23 CPOX CR1L DPF3 GMPR FHDC1

1.49e-051851907e8f7da9641b6cf1db1093b4f301ce828fd3a529c
ToppCelldroplet-Thymus-nan-24m-Myeloid-B_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BIN1 MYO1E RPS6 LRRK2 NFKB2 LTB BANK1

1.49e-051851907d7fed17356f8bf5900fd106f25b4f7501ad7b590
ToppCelldroplet-Thymus-nan-24m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BIN1 MYO1E LRRK2 SAMHD1 NFKB2 LTB BANK1

1.49e-051851907a92bd84e44fc992b7eeefaa2ff8091ed09f0df00
ToppCellmoderate-Lymphoid-NK|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FAT4 PDLIM3 KCNJ13 SERPINE1 TRPM1 GPR176 NOVA1

1.49e-0518519074979a787acbc9b4ca8defe91cc79b674e51af1bf
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MYH9 MYO9B ZNF385D PDLIM3 PGAP1 SERPINE1 GPR176

1.49e-051851907e58a009aaf342be019a909747b1895d5987d4daf
ToppCelldroplet-Thymus-nan-24m-Myeloid-professional_antigen_presenting_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BIN1 MYO1E LRRK2 SAMHD1 NFKB2 LTB BANK1

1.49e-051851907877eb127ac797f8a1e1a9e0049fa16cae16cfa35
ToppCellImmune-enucleated_erythrocyte|World / Lineage, Cell type, age group and donor

MAN1A1 SLC22A23 CPOX CR1L DPF3 GMPR FHDC1

1.55e-051861907f9d5ec5cc8fd6e63bf25abe390307ec8a4a2d5a3
ToppCell368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DOCK4 NUP85 TNRC6B PHAF1 UBE2H COG5 DNAH11

1.55e-05186190777bebf576eb9b96ecb4fefb8a82a31aaaa917fc0
ToppCell368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DOCK4 NUP85 TNRC6B PHAF1 UBE2H COG5 DNAH11

1.55e-05186190713bc41c60fd628af31899a5e8b480e06cc4781be
ToppCellsevere_influenza-RBC|World / disease group, cell group and cell class (v2)

SLC22A23 CPOX CR1L UBE2H PKLR GMPR FHDC1

1.60e-051871907f846750575f318503d21ade30f5bfd2e1d4c84af
ToppCellRV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

AKAP6 NEBL TRPM7 MYH7B ART3 DPF3 GMPR

1.60e-05187190778cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

DOCK4 COL6A6 SAMHD1 PDLIM3 PGAP1 MACF1 ARHGAP28

1.60e-05187190792d468dde81125d51daf7abd4703741abe1ab91c
ToppCellFetal_29-31_weeks-Immune-enucleated_erythrocyte|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MAN1A1 SLC22A23 CPOX CR1L DPF3 GMPR FHDC1

1.71e-0518919071900e574870fc647bfa11c732a72f3d38aab717c
ToppCellRV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

AKAP6 NEBL TRPM7 MYH7B ART3 DPF3 PDZD2

1.71e-0518919075e80c47f63980904c4c1ff02c201b67b456a0974
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 SAMHD1 CBLB MDN1 SERPINE1 MGAT4C GPR176

1.77e-051901907048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BIN1 MAN1A1 MYO1E LRRK2 RPL10A MACF1 BANK1

1.77e-051901907ee7b60cdf93c695ea2d59a170ca8cf4dc93e7eb2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 SAMHD1 CBLB MDN1 SERPINE1 MGAT4C GPR176

1.77e-0519019071121eb607a984c59fbffe7220837fc178745aa55
ToppCellLV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

AKAP6 NEBL TRPM7 MYH7B ART3 DPF3 PDZD2

1.77e-051901907de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCelldroplet-Lung-nan-21m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BIN1 MAN1A1 MYO1E RPS6 PGAP1 LTB BANK1

1.77e-051901907046de398870b6d483466f369813b100c22743301
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL6A6 NTRK2 NTRK3 GSN ZNF385D PDLIM3 NOVA1

1.90e-0519219078d56e360ebc624ca4cd7f0af4f3cc599c244f134
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

TNRC6B PTK2 SCAPER MACF1 SSH2 FGGY PDZD2

1.90e-051921907e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FAT4 NDST4 ITGB8 ZNF385D SYT1 ARHGAP28 NOVA1

1.90e-05192190772881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCellMesenchymal-matrix_fibroblast_2_cell|World / Lineage, Cell type, age group and donor

FAT4 COL6A6 NTRK2 NTRK3 ZNF385D PDLIM3 NOVA1

1.90e-051921907a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MAN1A1 SLC22A23 CR1L UBE2H DPF3 GMPR FHDC1

1.96e-051931907305e15ee467826ee08b2617c69f250ad39c11b19
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-hematologic-erythrocytic|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MAN1A1 SLC22A23 CR1L UBE2H DPF3 GMPR FHDC1

1.96e-051931907dd376664906caccc9c2065f8e7a364509e18a5cc
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FAT4 COL6A6 NTRK2 NTRK3 GSN ZNF385D NOVA1

2.03e-051941907439d3f17c1f4736122b330e98add9292c7036a8e
ToppCellRV-02._Fibroblast_II|World / Chamber and Cluster_Paper

SLC9A9 MAN1A1 CBLB GSN SERPINE1 SSH2 NOVA1

2.10e-051951907ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HYKK SLC22A23 AR ITGB8 CROT SRGAP3 ALDH7A1

2.10e-0519519076c9c58322c1df891bb4bab56dacb542c8777bb7d
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_3|Classical_Monocyte / Disease condition and Cell class

MYH9 CCDC186 CYP19A1 SAMHD1 VSIR TLN1 ATP5F1B

2.17e-05196190715397ec27167bb2fb6fec120b68bf38fc71b2670
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HYKK SLC22A23 AR ITGB8 CROT SRGAP3 ALDH7A1

2.24e-051971907107cb153ea7fc74bbd244dbb9d0499c0a8506724
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DOCK4 SLC9A9 CBLB SRGAP3 MACF1 ARHGAP28 OSTF1

2.24e-05197190731a1852911bda38543916585fda34255fd62a134
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SLC9A9 COL6A6 CBLB SRGAP3 MACF1 ARHGAP28 OSTF1

2.24e-0519719070034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCellIPF-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

DOCK4 FAT4 NEBL COL6A6 ITGB8 MACF1 ARHGAP28

2.24e-051971907f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 SAMHD1 CBLB MDN1 PDLIM3 SERPINE1 GPR176

2.31e-051981907a860246bcea847249a78fd2e86ed8e04371060db
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SLC9A9 FAT4 COL6A6 ZNF385D SRGAP3 MACF1 ARHGAP28

2.31e-05198190717dc055e2a289496d9c5cdbf3297bdf906dc6d22
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AMN SLC22A23 ITGB8 CROT SRGAP3 PGAP1 ALDH7A1

2.47e-0520019078827653738a931e4a4545e0c7d75be12bed40740
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Mesenchymal-BMP_responsible_cell|GW26 / Sample Type, Dataset, Time_group, and Cell type.

PALD1 SLC9A9 VSIR GSN TLN1 OSTF1 NCKAP1L

2.47e-052001907cd0d69f973ca3204b500d12031b403a1f4593431
ToppCellfacs-Liver-Hepatocytes-3m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPS1 ITIH2 CROT UGT2A3 CES3 ALDH6A1

2.95e-0513919064ddfbc36a0560fb70594627178bff652ab1ea3e9
ToppCellfacs-Liver-Hepatocytes-3m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPS1 ITIH2 CROT UGT2A3 CES3 ALDH6A1

2.95e-05139190682bf5ba69a907fbd9b4e2b2dd1dd27b8c4c75f25
ToppCellfacs-Liver-Hepatocytes-3m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPS1 ITIH2 CROT UGT2A3 CES3 ALDH6A1

2.95e-051391906fc9ac09c2106e88104a52575832d71d17765eec8
ToppCellfacs-Liver-Hepatocytes-3m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPS1 ITIH2 CROT UGT2A3 CES3 ALDH6A1

2.95e-051391906fc4b39ac9a10cf0acacfebbc4295edf324d930d5
ToppCellRV-14._Fibroblast_III|RV / Chamber and Cluster_Paper

SLC9A9 FADS6 GSN PGAP1 KCNJ13 SERPINE1

3.08e-051401906b4fee8eb6bf855b364b00bda3f78e49d851bbca0
ToppCell10x5'-Lung-Myeloid_Mac-Intestinal_macrophages|Lung / Manually curated celltypes from each tissue

AKAP6 PALD1 SLC9A9 CR1L SPICE1 PDLIM3

3.20e-0514119067671d300b1722711fd2d8034b96a3aa7e3ccb560
ToppCellBac-SEP-Lymphocyte-T_NK-CD8_TCM|Bac-SEP / Disease, Lineage and Cell Type

BIN1 LYPLA2 RPS6 MDN1 KCNJ13 LTB

4.20e-0514819065814bfb5060bac455334eb50d2a7b1f01c0b6831
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PALD1 AZIN2 MAP3K14 LRRK2 NFKB2 PABPC1L

4.53e-0515019067a381f5ae94eba5eb60dcbf83416b4eb18c279ea
ToppCellSevere_COVID-19-undefined|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

MAN1A1 NTRK3 ITGB8 FAN1 EXOC3L4 CXCL5

4.70e-0515119062ae403417fcb3fe402f6f47bb60ffa68d5fefd2a
ToppCellSevere_COVID-19-undefined-undefined|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

MAN1A1 NTRK3 ITGB8 FAN1 EXOC3L4 CXCL5

4.70e-051511906b402185dd7a93c6d0ec5c4d84d5031a157ee8cfb
ToppCellCOVID-19-Heart-CM_5_(RYR2-)|Heart / Disease (COVID-19 only), tissue and cell type

BIN1 CLTCL1 SLC22A23 CHRND ART3 CES3

5.43e-051551906d7e26696fd9c0a759524f331243db43059b33ed9
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CEL TRPM7 NSD2 DRC1 ZNF385D CPO

5.63e-0515619064d2679e7639758c49fc25a2deb9109b08f0a3e57
ToppCellwk_08-11-Hematologic-Meg-ery-Platelet|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

MYH7B CR1L EXOC3L4 SERPINE1 GMPR CXCL5

6.48e-051601906e0591f95f3f47ffbe013ebbebf6bed8c7c344732
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_1|E16.5-samps / Age Group, Lineage, Cell class and subclass

DOCK4 NEBL GSN EXOC3L4 MACF1 HSD11B1

7.18e-051631906f1ec2625b52664308968b01d8e0275e1e0751480
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD4-Teffector/EM_CD4|GI_small-bowel / Manually curated celltypes from each tissue

RPS6 NTRK2 NTRK3 RPL10A LTB FHDC1

7.68e-051651906ecaeb90a6bc27524ef6f2eefa72aec7315dbde3b
ToppCellInt-URO-Myeloid-tDC|Int-URO / Disease, Lineage and Cell Type

PALD1 MYO1E HSPA12B AR SCN9A ALDH7A1

7.68e-0516519069803c3db6cdcf925bea7d9c382bf4fd05acf3509
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Reln_Tac1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DOCK4 AMN MYO1E PDLIM3 SCN9A GPR176

7.94e-05166190659d47c1fca7a8c70f6998f3367a9dbcb9b67966f
ToppCellfacs-Heart-RV-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMGDH GSN UGT2A3 PKLR CES3 HSD11B1

8.21e-0516719063e3d8f6df2feefafad5b44ba0ebf5b5a0fe4ed58
ToppCellfacs-Heart-RV-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMGDH GSN UGT2A3 PKLR CES3 HSD11B1

8.21e-0516719063ad9f3122dbe96580f640388ef920ea209fc2349
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)|368C / Donor, Lineage, Cell class and subclass (all cells)

PALD1 SRGAP3 SCN9A RPGR MGAT4C IPO11

8.48e-051681906a74c8a9e3299183fba31ce3053ef325b5dbcd104
DrugIsoflupredone acetate [338-98-7]; Up 200; 9.6uM; PC3; HT_HG-U133A

FAT4 CLTCL1 NEBL NSD2 NASP HEATR1 CPS1 PTK2 SERPINE1 COG5 CXCL5

4.43e-07188186111832_UP
DiseaseDental enamel hypoplasia

MYH7B SCAPER SYT1

5.28e-05121873EFO_1001304
DiseaseAdenocarcinoma of lung (disorder)

CYP2A13 NTRK2 NTRK3 KEAP1 IPO4 RPL10A NEK1 FASN

5.40e-052061878C0152013
DiseaseMalignant neoplasm of breast

AKAP6 MYH9 HK3 NSD2 RPS6 CYP19A1 RPS6KA3 NUP214 KEAP1 AR GSN CHRND FASN TRMT10A SRGAP3 NIP7 MACF1 BOD1L1 HSD11B1

5.70e-05107418719C0006142
Diseasecreatine measurement

CPS1 SLCO1B7 METTL15 MGAT4C

7.85e-05361874EFO_0010472
DiseaseWarsaw breakage syndrome (implicated_via_orthology)

DDX11 DDX11L8

1.19e-0431872DOID:0060535 (implicated_via_orthology)
Diseaseidiopathic interstitial pneumonia (is_marker_for)

KEAP1 CXCL5

2.38e-0441872DOID:2797 (is_marker_for)
DiseaseKidney Failure, Chronic

MYH9 PPARA FASN SERPINE1

2.44e-04481874C0022661
Diseasemean platelet volume

SLC9A9 MYH9 MYO1E COL6A6 MYO9B SLC22A23 POLR2A LRRK2 DNM1L CPS1 ST7L RGS12 EXOC3L4 GLS ANKDD1A BANK1 ATP5F1B

2.85e-04102018717EFO_0004584
Diseasepolycystic ovary syndrome (biomarker_via_orthology)

CYP19A1 STAR ATP5F1B

3.06e-04211873DOID:11612 (biomarker_via_orthology)
DiseaseObesity

NTRK2 PPARA FASN SERPINE1 HSD11B1 ALDH6A1 FGGY

3.48e-042051877C0028754
Diseaseblood pressure

SLC9A9 VPS37A BANK1

3.53e-04221873EFO_0004325
Diseasetriacylglycerol 58:9 measurement

CPOX NFKB2 CPO

3.53e-04221873EFO_0010443
Diseasetype 2 diabetes mellitus (biomarker_via_orthology)

DNM1L STAR SERPINE1 HSD11B1 GPT2 ATP5F1B

3.61e-041471876DOID:9352 (biomarker_via_orthology)
Diseasecortical surface area measurement

PALD1 SLC9A9 MYO9B CAPN2 MAP3K14 TNRC6B CPS1 ST7L PLXNB2 ITGB8 SACM1L GLS SYT1 MACF1 ARHGAP28 SSH2 BANK1 NOVA1 DNAH11 PDZD2

3.67e-04134518720EFO_0010736
Diseaseresponse to rifampicin, response to efavirenz, drug-induced liver injury

NEBL SYT1

3.95e-0451872EFO_0004228, EFO_0006904, EFO_0007866
Diseaseribitol measurement

NASP FGGY

3.95e-0451872EFO_0800143
DiseaseParoxysmal atrial fibrillation

AKAP6 NEBL PTK2 DPF3 XXYLT1 COG5

4.95e-041561876C0235480
Diseasefamilial atrial fibrillation

AKAP6 NEBL PTK2 DPF3 XXYLT1 COG5

4.95e-041561876C3468561
DiseasePersistent atrial fibrillation

AKAP6 NEBL PTK2 DPF3 XXYLT1 COG5

4.95e-041561876C2585653
Diseaseprostate carcinoma, type 2 diabetes mellitus

AKAP6 LMTK2 TNRC6B AP3S2

5.42e-04591874EFO_0001663, MONDO_0005148
DiseaseAtrial Fibrillation

AKAP6 NEBL PTK2 DPF3 XXYLT1 COG5

5.66e-041601876C0004238
DiseaseDepressive Symptoms

CYP19A1 FASN SERPINE1

5.85e-04261873C0086132
Diseasediastolic blood pressure, social deprivation

ST7L BANK1

5.89e-0461872EFO_0006336, EFO_0009696
Diseaseleiomyoma (is_implicated_in)

AR PTK2

5.89e-0461872DOID:127 (is_implicated_in)
DiseaseQRS duration

FAT4 NEBL CES5A MYH7B SYT1 COG5 MGAT4C ATP5F1B

6.61e-042981878EFO_0005055
DiseaseCiliopathies

ACVR2B NEK1 KCNJ13 RPGR DNAH11

6.93e-041101875C4277690
DiseaseHyalinosis, Segmental Glomerular

MYH9 MYO1E SERPINE1

7.30e-04281873C0086432
DiseasePilomyxoid astrocytoma

NTRK2 SRGAP3

8.22e-0471872C1519086
DiseaseCongenital Pain Insensitivity

CLTCL1 SCN9A

8.22e-0471872C0002768
DiseaseMASA syndrome (implicated_via_orthology)

TRPM7 TRPM1

8.22e-0471872DOID:0060246 (implicated_via_orthology)
DiseaseMicrocephaly

NSD2 DNM1L NUP214 GPT2

8.77e-04671874C0025958
Diseaseplatelet measurement

MYO9B LRRK2 DNM1L CPS1 ST7L EXOC3L4 ANKDD1A BANK1

9.46e-043151878EFO_0005036
Diseasereticulocyte count

MYH9 MYO9B CYP19A1 PPIL6 TNRC6B PLXNB2 AR DPF3 GLS PKLR GMPR FHDC1 UBE2Z ATP5F1B PDZD2 KPNA3

1.06e-03104518716EFO_0007986
DiseaseLarge cell carcinoma of lung

NTRK3 LMTK2 NEK1

1.09e-03321873C0345958
DiseaseQT interval, response to tricyclic antidepressant

CPOX CPO

1.09e-0381872EFO_0004682, EFO_0007916
DiseaseAlcohol withdrawal syndrome

CYP19A1 AR

1.09e-0381872C0236663
DiseaseAcute Coronary Syndrome

PSMB1 GSN FASN

1.19e-03331873C0948089
Diseaseelectroencephalogram measurement

FAM47A PPARA ARHGAP28 OSTF1

1.27e-03741874EFO_0004357
Diseasetestosterone measurement

DOCK4 MYO9B CYP19A1 POLR2A UGT2A2 PPARA ST7L AR IFNAR2 PNMA6F IFNW1 FASN PGAP1 C18orf63 MACF1 METTL15 BANK1 KPNB1

1.30e-03127518718EFO_0004908
Diseasebehavioural disinhibition measurement

PALD1 PPARA CPS1 DNAH11

1.34e-03751874EFO_0006946
Diseaseintellectual disability (implicated_via_orthology)

CAPN2 PSMB1 NDST4 BOD1L1

1.34e-03751874DOID:1059 (implicated_via_orthology)
Diseaseserum alanine aminotransferase measurement

CELF6 TRPM7 MYH7B NDST4 CPS1 PLXNB2 RGS12 DDX11 PARP6 TRMT10A CROT NUP210 ATP5F1B ARMC6

1.36e-0386918714EFO_0004735
DiseaseTodd Paralysis

TRPM7 CHRND

1.40e-0391872C0234544
DiseaseExperimental Autoimmune Encephalomyelitis

PPARA CBLB

1.40e-0391872C0014072
DiseaseParalysed

TRPM7 CHRND

1.40e-0391872C0522224
DiseaseGestational Diabetes

CYP19A1 AR

1.40e-0391872C0085207
DiseaseAutistic Disorder

DOCK4 SLC9A9 NTRK2 CYP19A1 AR UBE2H SERPINE1

1.44e-032611877C0004352
DiseaseFocal glomerulosclerosis

MYH9 MYO1E SERPINE1

1.53e-03361873C0017668
Diseasechronic obstructive pulmonary disease

AKAP6 MYH9 NEBL HYKK IFT81 ITGB8 SRGAP3 DPF3 SSH2 NOVA1 PDZD2 KPNA3

1.54e-0368818712EFO_0000341
Diseasevisceral heterotaxy (implicated_via_orthology)

DRC1 ACVR2B DNAH11

1.66e-03371873DOID:0050545 (implicated_via_orthology)
DiseaseImmature Reticulocyte Fraction Measurement

PKLR GMPR

1.74e-03101872EFO_0009253
Diseasecreatinine measurement

DMGDH CEL MYH7B MAP3K14 NASP TNRC6B ACVR2B CPS1 CBLB PLXNB2 AR RGS12 DPF3 SYT1 KPNA3

1.76e-0399518715EFO_0004518
Diseaseblood molybdenum measurement

AKAP6 ZNF385D MGAT4C

1.79e-03381873EFO_0007582
Diseasesleep duration

SLC9A9 NEK1 SRGAP3 PABPC1L COG5 BANK1 NOVA1 PDZD2

2.27e-033621878EFO_0005271
DiseaseIntellectual Disability

AKAP6 NSD2 SNX14 FASN SRGAP3 SCAPER SYT1 MACF1 GPT2

2.30e-034471879C3714756
Diseaseobsolete_red blood cell distribution width

CEL NAT9 MYO9B SLC22A23 SAMHD1 CPS1 ST7L CR1L VSIR PTK2 DPF3 UGT2A3 NUP210 SCAPER GMPR COG5 ALDH6A1 KPNB1

2.37e-03134718718EFO_0005192
Diseaseobesity (implicated_via_orthology)

FAT4 CAPN2 PLXNB2 AR HSD11B1 ATP5F1B

2.57e-032151876DOID:9970 (implicated_via_orthology)
Diseaseatrial fibrillation

AKAP6 NEBL POLR2A PTK2 DPF3 XXYLT1 COG5 BANK1

2.64e-033711878EFO_0000275
DiseaseGastric Adenocarcinoma

TRPM7 NTRK3 RPS6KA3

2.92e-03451873C0278701
Diseasesmoking status measurement, ulcerative colitis

CELF6 PARP6

2.98e-03131872EFO_0000729, EFO_0006527
Diseasedimethylglycine measurement

DMGDH ZNF385D DPF3

3.11e-03461873EFO_0010476
DiseasePrimary Ciliary Dyskinesia

DRC1 RPGR DNAH11

3.31e-03471873C4551720
Diseasehypoxanthine mesurement

XXYLT1 GMPR

3.46e-03141872EFO_0010500
DiseaseKartagener syndrome (implicated_via_orthology)

DRC1 DNAH11

3.46e-03141872DOID:0050144 (implicated_via_orthology)
DiseaseEndometrioma

CYP19A1 NTRK3 LRRK2 ITGB8 ARHGAP28

3.70e-031611875C0269102
DiseaseEndometriosis

CYP19A1 NTRK3 LRRK2 ITGB8 ARHGAP28

3.70e-031611875C0014175
Diseaseceramide measurement

NTRK2 CPS1 SLCO1B7 MDN1 ART3 M6PR

3.97e-032351876EFO_0010222
Diseaseattention deficit hyperactivity disorder, autism spectrum disorder, intelligence

AKAP6 SLC22A23 NTRK3 DPF3 SYT1 METTL15 BANK1 NOVA1

4.03e-033981878EFO_0003756, EFO_0003888, EFO_0004337
DiseaseWeight Gain

GSN FGGY IPO11 DNAH11

4.10e-031021874C0043094
DiseaseRetinitis Pigmentosa

BEST1 SCAPER FSCN2 RPGR

4.39e-031041874C0035334
Diseasecongenital myasthenic syndrome (implicated_via_orthology)

CHRND SYT1

4.52e-03161872DOID:3635 (implicated_via_orthology)
Diseasephosphatidylcholine 38:6 measurement

CPOX CPO

4.52e-03161872EFO_0010388
Diseaseperipheral arterial disease

NEBL HYKK SYT1

4.90e-03541873EFO_0004265
DiseaseLeukemia, Myelocytic, Acute

NTRK3 CAPN2 NUP214 CBLB SLX4

5.01e-031731875C0023467
DiseaseStreptozotocin Diabetes

PPARA SERPINE1 PKLR HSD11B1

5.02e-031081874C0038433
DiseaseDiabetes Mellitus, Experimental

PPARA SERPINE1 PKLR HSD11B1

5.02e-031081874C0011853
DiseaseAlloxan Diabetes

PPARA SERPINE1 PKLR HSD11B1

5.02e-031081874C0002152
DiseaseSjogren's syndrome (implicated_via_orthology)

CYP19A1 MAP3K14

5.10e-03171872DOID:12894 (implicated_via_orthology)
Diseaseerythritol measurement

NASP BANK1

5.10e-03171872EFO_0021171
Diseaselymphocyte count

PALD1 AMN CEL PPIL6 TNRC6B SAMHD1 KEAP1 CPS1 PLXNB2 TRIP12 VSIR UBE2H TLN1 NFKB2 SSH2 PPP2R3C RPAP2 KPNA3

5.63e-03146418718EFO_0004587
Diseaseuric acid measurement

FAT4 CEL TRPM7 IFT81 LMTK2 CPS1 AR DPF3 SYT1 IPO11

5.75e-0361018710EFO_0004761
Diseasepre-eclampsia (is_marker_for)

ACVR2B GSN SERPINE1

5.98e-03581873DOID:10591 (is_marker_for)
Diseaseimmature platelet fraction

MYO9B ST7L EXOC3L4 ANKDD1A

6.07e-031141874EFO_0009187

Protein segments in the cluster

PeptideGeneStartEntry
GDLQQRVVMPDFKIH

nan

366

A8MVM7
MDPIQKAVINHTFGV

ZNF385D

56

Q9H6B1
MKALEFPAGSVHVNV

BANK1

251

Q8NDB2
FIPAKAVEAAQAHQM

GPT2

446

Q8TD30
PLMDKVVTFAGHLQR

EXOC3L4

546

Q17RC7
KPAVDGANFIVNHMR

CHRND

436

Q07001
PNGMNKGEHALVLFE

CCDC186

181

Q7Z3E2
LQKIVPDGHTFMQAG

ANTXRL

141

A6NF34
NIQDSVPKAVMHFLV

DNM1L

661

O00429
PLHTKQAVSMFLGAV

ALDH7A1

371

P49419
ANKAEMELVQHIGIP

AZIN2

91

Q96A70
MLYKNDPVGAIHNAE

BCS1L

401

Q9Y276
AALQAMKAHPQKAGV

ARMC6

416

Q6NXE6
QQMPRGNHFTIDEVK

FAT4

1461

Q6V0I7
MIQAILVFNNHGKPR

AP3S2

1

P59780
QIECGHVVLNKNMPF

DNAH11

616

Q96DT5
HKNGQHFIIPQMADS

GIT2

241

Q14161
HLVQAGFMTPAEHKQ

BEST1

156

O76090
PADKMVSVLVQEGHA

AMN

51

Q9BXJ7
DHHQLPPVIKNMAFQ

AQR

1096

O60306
AVSGIVHMQAAPKEE

HSD11B1

226

P28845
GHIFASIDMPAINKG

CEL

341

P19835
VPGNAKEEHLNMFIQ

CBWD5

281

Q5RIA9
HPEMIQVGQKAANAL

CPO

256

Q8IVL8
LGPVAAVAAQMQHVA

CELF6

266

Q96J87
VPAHMFGVTKFGDNI

ECD

71

O95905
QPFQVAEVFTGHMGK

ATP5F1B

466

P06576
DDKPHNPMVNAGAIV

GLS

326

O94925
FQVVMKVVQLLPDGH

PALD1

706

Q9ULE6
LMKIHGQDPVSFQDV

PPP2R3C

376

Q969Q6
AHDVQNPLHFGEMKV

NUP210

516

Q8TEM1
HTQNKEALVAVPLGM

NUP210

1386

Q8TEM1
NKPGMNLLHFVAQEA

FHDC1

331

Q9C0D6
EMSGVNQKIPFDIHC

MGAT4C

441

Q9UBM8
AKNHGVVMPDANKEN

ALDH6A1

286

Q02252
PMIIHQLAKGDFGTQ

KPNA3

371

O00505
EVVKAHPRFMLFATQ

MDN1

1181

Q9NU22
EVAVLANMKHPNIVQ

NEK1

51

Q96PY6
EMFHIGQQQIFKPTE

GPR176

371

Q14439
GQFMQEPKIHIFNER

ITIH2

861

P19823
NKFLRAHGPDAMILV

NTRK3

626

Q16288
MATVIHNPLKALGDQ

DPF3

1

Q92784
LAKMQLHGIAQPVTA

GABPA

426

Q06546
NRQDAPHLVKGAMAA

RPS6KA3

691

P51812
LTVNGFVEPHKNMEV

IPO11

221

Q9UI26
IDVHMDPNIGKRLNA

KIAA1109

3456

Q2LD37
SHMLAEIKAIFPNGQ

CBLB

151

Q13191
VPGNAKEEHLNMFIQ

CBWD2

281

Q8IUF1
VPGNAKEEHLNMFIQ

CBWD1

281

Q9BRT8
ENKTPGVMDAFLVLH

MYH7B

726

A7E2Y1
GHARALMQAKTLFPN

PCYT1B

91

Q9Y5K3
VFPVLAAKHCIMQAN

PDCD6IP

241

Q8WUM4
QKAVEKGAVHPAMAN

PNMA6F

366

A0A0J9YX94
VIPMNHETDVNFQGK

PLXNB2

676

O15031
MHQVAIAAKDPANGR

NUP85

116

Q9BW27
ANGVMIFLINIDPHL

OR2T6

41

Q8NHC8
QPQLVVHVGMDTAAK

PGPEP1L

46

A6NFU8
LAINGKPLVGLMHFD

PDZD2

2801

O15018
VNNHECGFLLPMKEA

CES5A

341

Q6NT32
VMQKFNGHDALPFIP

NSD2

61

O96028
AVVAHMDGKPNLIFQ

KCNJ13

176

O60928
HENPDLAKVMNLIVF

NCKAP1L

506

P55160
AKVENMIIPAQGHFG

LMAN1

231

P49257
AMHSFPANDEVQKLG

LRRK2

166

Q5S007
PVMAGIGEEIAHFQK

NUP214

701

P35658
GNFPVEAVKMQHAIA

PKLR

411

P30613
PSHQKIFDLMELNGV

LMTK2

646

Q8IWU2
RNAAVIDPLQFHMGV

RPS6KA5

386

O75582
GHVTIPGQQDKDMFQ

MYH9

306

P35579
VHCLSPQKGQIFLDM

METTL15P1

81

P0C7V9
KALPGFRNLHVDDQM

AR

721

P10275
LNKEFALEHGIPINM

NDST4

401

Q9H3R1
LAAAPLHEQKQMIGE

PABPC1L

536

Q4VXU2
MANETQKVGAIHFPF

DDX11

1

Q96FC9
AVNGKTMPALEVFAH

HSPA12B

161

Q96MM6
VHCLSPQKGQIFLDM

METTL15

81

A6NJ78
ENFSVPHNKRGVLGM

PPIL6

231

Q8IXY8
HESLNPGAQRFEKMI

HK3

296

P52790
HPNDVLKILEAFVMG

DRC1

621

Q96MC2
QKHLVMGDIPAAVNA

NASP

51

P49321
PQAEMFEHLSGKLQQ

MACF1

4221

Q9UPN3
HALMVFRVAKVFAQP

SMPD4

501

Q9NXE4
IVGFTNHINVMVKFP

IFNAR2

141

P48551
KRGVPQINEQMLFHG

PARP11

191

Q9NR21
QLRPGAEANFMLKVH

ITGB8

126

P26012
PQLVAMIVNHLKSQG

BOD1L1

51

Q8NFC6
VTKAIHALMENAVQP

COG5

591

Q9UP83
NEGIMHESKPFFAVQ

CPS1

361

P31327
FPQEMVKGSQLQKAH

IFNW1

61

P05000
ELHFLQKVVSEPAMG

IFT81

291

Q8WYA0
DMILNEIKQGKFHNP

CBLIF

251

P27352
EIKQGKFHNPMSIAQ

CBLIF

256

P27352
QNHIIMFLKAAGFPT

HYKK

81

A2RU49
VMKHLPGPQQQAFKE

CYP2A13

226

Q16696
FGLAVHEKFVPQDMR

DOCK4

1556

Q8N1I0
GMHEKGIIFNNNPEL

CYP19A1

126

P11511
KLIDHMVQGHAAFPE

FGGY

336

Q96C11
MVQGHAAFPELQVKA

FGGY

341

Q96C11
GGLSKNPLFVQMHAD

FGGY

456

Q96C11
VAGHASDKIENMVPV

COX11

131

Q9Y6N1
DPVNGMAHVIKDIQF

CR1L

101

Q2VPA4
MANETQKVGAIHFPF

DDX11L8

1

A8MPP1
VPGNAKEEHLNMFIQ

CBWD3

281

Q5JTY5
VPGNAKEEHLNMFIQ

CBWD6

281

Q4V339
QINFHGDELHPMKAA

AMDHD1

256

Q96NU7
LKGDQENVHPDVMLV

KPNB1

776

Q14974
ANVIPKVGFTNISHM

DMGDH

556

Q9UI17
ALIEHEMKNGIPANR

LYPLA2

101

O95372
SHLSGNPIFAEKVMN

MAN1A1

361

P33908
AFVEQVEAQLMAKHP

FAM47A

116

Q5JRC9
QDAPAAQFMAHKVVL

KEAP1

86

Q14145
HGPVEALKQMLFNLQ

LAS2

291

Q8IYD9
VVQGKEPAHLMSLFG

GSN

526

P06396
VAGIFPDKVLHNIMS

HEATR1

1311

Q9H583
RAKFPEHTIMAGNVV

GMPR

146

P36959
EKPFHSVPFLMGVNN

CES3

331

Q6UWW8
KFDLSQNHPLGMAIF

FASN

1771

P49327
QNHPLGMAIFLKNVT

FASN

1776

P49327
DLPPGFMFKVQAQHD

BIN1

516

O00499
LEEAGFKMPCQLHQV

CAPN2

631

P17655
VDENPKMAIFLQHAA

SCAPER

1126

Q9BY12
PQISKVANHMDGFQR

SACM1L

276

Q9NTJ5
AAFGHVQRAEMLPKT

CPOX

91

P36551
GETPKHFAVQVVDML

IPO4

326

Q8TEX9
VGFKNMQNVEHVPLS

PSMB1

181

P20618
KMGQIINIFHAIPAA

C18orf63

206

Q68DL7
QGVHPKMISNLQVFA

CXCL5

56

P42830
HGVMPNKETEFLLIQ

ECSIT

171

Q9BQ95
EVVGMFNIAPHKVRV

COL6A6

461

A6NMZ7
IFQHIGLPMFSRDNK

FADS6

246

Q8N9I5
VHKVGNTPLDMNQFR

CROT

146

Q9UKG9
EQHVFQNGSMLKPAV

PARP6

291

Q2NL67
GGHKDIVEMLFTQPN

OSTF1

116

Q92882
QIPNNVAHATEGKMA

MAP3K14

116

Q99558
AVHGFIAEKIREMPQ

NOVA1

111

P51513
GKASNNPPFVIHDME

PPARA

231

Q07869
FVQRDLKLVQGFMPH

SERPINE1

121

P05121
ATPLGPQEMAKNHIF

MROH5

701

Q6ZUA9
MPTNGLHQVLKIQFG

FSCN2

1

O14926
MVVFAAPHRGVAKEI

RPGR

361

Q92834
FQQLPEMAVQDVKHV

FAN1

766

Q9Y2M0
MKQIGNVAALPGIVH

RTCB

66

Q9Y3I0
EQLAQAMFDHIPVGV

RTCB

141

Q9Y3I0
VKVHAASVNPIDVNM

RTN4IP1

76

Q8WWV3
IPQNVIHFILKDMLG

RTL1

711

A6NKG5
IGEFKVPMNTVDFGH

SYT1

241

P21579
HVDKAIALQPENPMA

RMDN3

351

Q96TC7
NDKQGFPMKQGVLTH

RPS6

56

P62753
NPHQGNAILEKMTFD

SLC9A9

116

Q8IVB4
FEHLINSNGIKPVME

SAMHD1

241

Q9Y3Z3
FGMLTAPIIELHNQK

SLC22A23

581

A1A5C7
VDPMAIVVFHQADIG

NIP7

156

Q9Y221
LMHGVKPFQGVKNND

PTK2

616

Q05397
HPMTEEFKNVLAIGN

SCN9A

766

Q15858
NMEHNRINKIPFGIF

SHOC2

361

Q9UQ13
QEFAPKSVAIIGHSM

PGAP1

161

Q75T13
LEMELPGVKIVHAQF

PDLIM3

176

Q53GG5
VQPELKALAIGFHSM

SLCO1B7

516

G3V0H7
LNFVKKHPLMEEQVG

SEMA4C

391

Q9C0C4
LGMPLAQAVAILQKH

PHAF1

21

Q9BSU1
AIKAHMNNIIEPRGE

SPICE1

681

Q8N0Z3
LLVADFGAMVNNPHL

SLX4

676

Q8IY92
EHLDPQMGDAVNVLK

AKAP6

1396

Q13023
AAQKGHVPVLAFIME

ANKDD1A

131

Q495B1
TPGMKHENLLQFIAA

ACVR2B

236

Q13705
AQNDFPVAMQIGAKH

CLTCL1

256

P53675
HAPQVADAILGNKMF

CLTCL1

591

P53675
AFAQHQAEVAKMEPL

CLCC1

236

Q96S66
NKFLRAHGPDAVLMA

NTRK2

626

Q16620
HLSLFFVVMKGPNDA

TRAF2

406

Q12933
RPFEEAAGNMVHVKQ

TMEM240

146

Q5SV17
MNKIFHPNIDEASGT

UBE2H

71

P62256
MVDPDLFNHKIHQGI

RGS12

341

O14924
QRLVVGAKGMEQFPH

M6PR

211

P20645
VFVEHMVPQDANQKG

SSH2

506

Q76I76
KFEFQPHMGDEVCQV

SRGAP3

331

O43295
EKGQHLEPFIMNFIN

SNX14

716

Q9Y5W7
PILGIQKHSQEGMVF

RPAP2

566

Q8IXW5
FGNMPEQKGVIRAEH

STAR

206

P49675
ELEKHGMQVPAQAQS

SYCE1

281

Q8N0S2
DPHFQDALMQLAKAV

TLN1

661

Q9Y490
SLMERGPHVKVQFQA

ARHGAP28

481

Q9P2N2
GPHVKVQFQALHLMV

ARHGAP28

486

Q9P2N2
QFHVATMVDNELPGL

POLR2A

311

P24928
HGAMELQVQTGKDAP

VSIR

161

Q9H7M9
HQFPEIMGIFAKAVL

ST7L

531

Q8TDW4
HLQGQTMQDPFGEKR

UBE2Z

291

Q9H832
AGKFPSLLTHNENMV

RPL10A

131

P62906
ISVHGGLQNFEMQPK

TRPM1

101

Q7Z4N2
VPIFGDQLDNIAHMK

UGT2A3

391

Q6UWM9
GINHAQLPLGNFVKM

TRMT10A

226

Q8TBZ6
VGEIKQFVSQLPHMQ

VPS33A

331

Q96AX1
DSRGLQVAHMFPAKQ

WDR31

216

Q8NA23
LSQMEQFPVKVHDFP

TRIP12

1226

Q14669
NPMLFHLVRDVKQGN

TRPM7

486

Q96QT4
PLVNNFTMHSDLGKI

VPS37A

101

Q8NEZ2
QPDNIAHMKAKGAAV

UGT2A2

406

P0DTE5
TQEANMHKNGAIVAP

TNRC6B

1411

Q9UPQ9
LFPIVEAMQKHFSAG

XXYLT1

181

Q8NBI6
VNISHPDMVDFARGK

LTB

221

Q06643
IGMEEHPELQQFVGK

MYO1E

746

Q12965
KTQIFLPMNFKDNHG

ART3

81

Q13508
VMEPAFIIQHFAGKV

MYO9B

626

Q13459
GQGNEPSIRMFQKLH

NAT9

146

Q9BTE0
SPMLNHVKNIGAFIS

NEBL

71

O76041
PKDMTAQFNNLGVLH

NFKB2

126

Q00653