Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionubiquitin-protein transferase activity

FBXO22 TRIM2 RNF144A RNF8 CUL9 RNF139 RNF217

2.41e-04473537GO:0004842
GeneOntologyMolecularFunctionubiquitin-like protein transferase activity

FBXO22 TRIM2 RNF144A RNF8 CUL9 RNF139 RNF217

3.88e-04512537GO:0019787
GeneOntologyMolecularFunctionubiquitin protein ligase activity

TRIM2 RNF144A RNF8 CUL9 RNF139 RNF217

4.40e-04372536GO:0061630
GeneOntologyMolecularFunctionaminoacyltransferase activity

FBXO22 TRIM2 RNF144A RNF8 CUL9 RNF139 RNF217

4.88e-04532537GO:0016755
GeneOntologyMolecularFunctionzinc ion binding

TRIM2 PRICKLE3 SUPT4H1 RNF144A RNF8 PRICKLE2 CUL9 RNF139 RNF217

5.09e-04891539GO:0008270
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

TRIM2 RNF144A RNF8 CUL9 RNF139 RNF217

6.28e-04398536GO:0061659
GeneOntologyMolecularFunctionacyltransferase activity

FBXO22 TRIM2 PNPLA1 RNF144A RNF8 CUL9 RNF139 RNF217

9.37e-04775538GO:0016746
GeneOntologyBiologicalProcessubiquitin-dependent protein catabolic process

FBXO22 TRIM2 ARRDC4 RNF144A RNF8 CUL9 CAV3 RNF139 RNF217

3.85e-05640549GO:0006511
GeneOntologyBiologicalProcessproteolysis involved in protein catabolic process

YOD1 FBXO22 TRIM2 ARRDC4 RNF144A RNF8 CUL9 CAV3 RNF139 RNF217

4.20e-058125410GO:0051603
GeneOntologyBiologicalProcessmodification-dependent protein catabolic process

FBXO22 TRIM2 ARRDC4 RNF144A RNF8 CUL9 CAV3 RNF139 RNF217

4.39e-05651549GO:0019941
GeneOntologyBiologicalProcessmodification-dependent macromolecule catabolic process

FBXO22 TRIM2 ARRDC4 RNF144A RNF8 CUL9 CAV3 RNF139 RNF217

4.66e-05656549GO:0043632
GeneOntologyBiologicalProcessprotein polyubiquitination

FBXO22 TRIM2 ARRDC4 RNF144A RNF8 RNF217

1.05e-04289546GO:0000209
GeneOntologyCellularComponentgamma-delta T cell receptor complex

TRGC1 TRGC2

9.76e-056542GO:0042106
GeneOntologyCellularComponentcell surface

IL1RAPL1 CCR2 CD19 TRGC1 TRGC2 SCNN1G KCNN2 ROS1 CAV3 VWDE

4.87e-0411115410GO:0009986
DomainIBR

RNF144A CUL9 RNF217

6.84e-0614513PF01485
DomainIBR

RNF144A CUL9 RNF217

6.84e-0614513SM00647
DomainLIM1_prickle

PRICKLE3 PRICKLE2

7.31e-062512IPR033725
DomainIBR_dom

RNF144A CUL9 RNF217

8.53e-0615513IPR002867
DomainLIM3_prickle

PRICKLE3 PRICKLE2

2.19e-053512IPR033727
DomainLIM2_prickle

PRICKLE3 PRICKLE2

2.19e-053512IPR033726
DomainPET_prickle

PRICKLE3 PRICKLE2

2.19e-053512IPR033723
DomainGPR137

GPR137C GPR137B

2.19e-053512IPR029723
DomainPET

PRICKLE3 PRICKLE2

1.09e-046512PF06297
DomainPET

PRICKLE3 PRICKLE2

1.09e-046512PS51303
DomainPET_domain

PRICKLE3 PRICKLE2

1.09e-046512IPR010442
DomainZF_RING_1

TRIM2 RNF144A RNF8 CUL9 RNF139 RNF217

1.36e-04291516PS00518
DomainZF_RING_2

TRIM2 RNF144A RNF8 CUL9 RNF139 RNF217

1.55e-04298516PS50089
DomainE3_UB_ligase_RBR

RNF144A RNF217

3.24e-0410512IPR031127
DomainZnf_RING_CS

TRIM2 RNF144A RNF8 CUL9

1.02e-03163514IPR017907
DomainRING

TRIM2 RNF144A RNF8 CUL9 RNF139

1.43e-03305515SM00184
DomainZnf_RING

TRIM2 RNF144A RNF8 CUL9 RNF139

1.91e-03326515IPR001841
DomainARM-type_fold

ARFGEF3 USP34 DIAPH2 CUL9 NUP188

2.27e-03339515IPR016024
DomainFHA

RNF8 KIF13A

2.64e-0328512SM00240
Domainzf-C3HC4

TRIM2 RNF144A RNF8 RNF139

3.19e-03223514PF00097
DomainFHA_DOMAIN

RNF8 KIF13A

3.23e-0331512PS50006
DomainFHA

RNF8 KIF13A

3.23e-0331512PF00498
DomainFHA_dom

RNF8 KIF13A

4.34e-0336512IPR000253
Domain-

RNF8 KIF13A

4.34e-03365122.60.200.20
Domain-

TRIM2 ROS1

5.08e-03395122.120.10.30
Domain6-blade_b-propeller_TolB-like

TRIM2 ROS1

7.01e-0346512IPR011042
DomainSMAD_FHA_domain

RNF8 KIF13A

8.88e-0352512IPR008984
DomainZnf_C3HC4_RING-type

TRIM2 RNF8 RNF139

1.16e-02172513IPR018957
Pubmed

Structure, organization, and somatic rearrangement of T cell gamma genes.

TRGC1 TRGC2

2.37e-0625423917858
Pubmed

Allelic differences in TCR gamma-chains alter gamma delta T cell antigen reactivity.

TRGC1 TRGC2

2.37e-0625428046225
Pubmed

Polymorphism of Tcrb and Tcrg genes in Biozzi mice: segregation analysis of a new Tcrg haplotype with antibody responsiveness.

TRGC1 TRGC2

2.37e-0625421973682
Pubmed

T cell-specific gamma genes in C57BL/10 mice. Sequence and expression of new constant and variable region genes.

TRGC1 TRGC2

2.37e-0625423486244
Pubmed

Physical linkage of mouse Tcrg-V genes. II. Regulatory features of the Vg4-Vg3 intergenic region.

TRGC1 TRGC2

2.37e-0625428119740
Pubmed

Organization of the murine T-cell receptor gamma locus.

TRGC1 TRGC2

2.37e-0625428244371
Pubmed

Regulation of RNF144A E3 Ubiquitin Ligase Activity by Self-association through Its Transmembrane Domain.

RNF144A RNF217

2.37e-06254226216882
Pubmed

RGS3 and IL1RAPL1 missense variants implicate defective neurotransmission in early-onset inherited schizophrenias.

IL1RAPL1 RGS3

2.37e-06254236318984
Pubmed

The genomic arrangement of T cell receptor variable genes is a determinant of the developmental rearrangement pattern.

TRGC1 TRGC2

2.37e-06254214691262
Pubmed

New T-cell receptor gamma haplotypes in wild mice and evidence for limited Tcrg-V gene polymorphism.

TRGC1 TRGC2

2.37e-0625428420824
Pubmed

Developmentally ordered V-J recombination in mouse T cell receptor gamma locus is not perturbed by targeted deletion of the Vgamma4 gene.

TRGC1 TRGC2

2.37e-0625429126983
Pubmed

Conservation of Tcrg-V5 and limited allelic sequence polymorphism of the other Tcrg-V genes used by mouse tissue-specific gd-T lymphocytes.

TRGC1 TRGC2

2.37e-0625428550103
Pubmed

Limited diversity of the rearranged T-cell gamma gene.

TRGC1 TRGC2

2.37e-0625423871915
Pubmed

Mapping genomic organization by field inversion and two-dimensional gel electrophoresis: application to the murine T-cell receptor gamma gene family.

TRGC1 TRGC2

2.37e-0625423375073
Pubmed

Langerhans cells are not required for epidermal Vgamma3 T cell homeostasis and function.

TRGC1 TRGC2

7.09e-06354221486908
Pubmed

Genetic polymorphism and exon changes of the constant regions of the human T-cell rearranging gene gamma.

TRGC1 TRGC2

7.09e-0635422879283
Pubmed

High-throughput microarray detection of olfactory receptor gene expression in the mouse.

OR2M5 OR2M3

1.42e-05454215377787
Pubmed

B cells modulate the expression of MHC-II on cardiac CCR2- macrophages.

CCR2 CD19

1.42e-05454233971183
Pubmed

Structure of a gammadelta T cell receptor in complex with the nonclassical MHC T22.

TRGC1 TRGC2

2.36e-05554215821084
Pubmed

The lysosomal GPCR-like protein GPR137B regulates Rag and mTORC1 localization and activity.

GPR137C GPR137B

2.36e-05554231036939
Pubmed

T cell receptor signaling for γδT cell development.

TRGC1 TRGC2

3.54e-05654230976362
Pubmed

Stoichiometry of the murine gammadelta T cell receptor.

TRGC1 TRGC2

4.94e-05754216418397
Pubmed

Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk.

TRGC1 TRGC2

4.94e-0575427477352
Pubmed

BRCA1 Haploinsufficiency Is Masked by RNF168-Mediated Chromatin Ubiquitylation.

CD19 RNF8

8.46e-05954230704900
Pubmed

Gene repression by Pax5 in B cells is essential for blood cell homeostasis and is reversed in plasma cells.

CCR2 CD19

8.46e-05954216546096
Pubmed

Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network.

TRIM2 RNF144A RNF8 RNF139

8.66e-0514954419549727
Pubmed

STAT5 is required for thymopoiesis in a development stage-specific manner.

TRGC1 TRGC2

1.83e-041354215294943
Pubmed

Interferon-driven deletion of antiviral B cells at the onset of chronic infection.

CCR2 CD19

2.13e-041454227872905
Pubmed

YOD1/TRAF6 association balances p62-dependent IL-1 signaling to NF-κB.

YOD1 RNF8

2.80e-041654228244869
Pubmed

The human T-cell receptor gamma (TRG) genes.

TRGC1 TRGC2

5.36e-04225422527426
Pubmed

A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system.

TRIM2 RNF8 RNF139

8.32e-0411854319690564
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

USP34 WASHC4 ZNF516 NUP188 BAHD1

1.37e-0352954514621295
CytobandEnsembl 112 genes in cytogenetic band chr6q22

RFX6 ROS1 RNF217

4.63e-04127543chr6q22
Cytoband7p14

TRGC1 TRGC2

5.78e-04305427p14
GeneFamilyPrickle planar cell polarity proteins|LIM domain containing

PRICKLE3 PRICKLE2

2.86e-0544021184
GeneFamilyRing finger proteins

TRIM2 RNF144A RNF8 RNF139 RNF217

3.34e-0427540558
GeneFamilyT cell receptor gamma locus at 7p14

TRGC1 TRGC2

1.07e-0322402375
GeneFamilyCyclins|F-boxes other

FBXO22 FBXO47

3.36e-0339402560
ToppCelldroplet-Pancreas-Endocrine-18m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 PTPRE PRICKLE3 RNF144A VKORC1L1 RGS3

7.75e-08185526512a195ebbae445afe3722a3943020080daf2f3c
ToppCellsevere-HLA-DR+_CD83+_Monocyte|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CCR2 PTPRE ARRDC4 DIAPH2 MPEG1 RNF217

1.16e-07198526a77f3440d7fb6a50066abc7e9ad59e83798ef13d
ToppCelldroplet-Spleen-nan-21m-Myeloid-macrophage|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTCHD1 ARRDC4 SCNN1G MPEG1 RGS3

1.73e-061725254fe5b91e4871bc6c5be57eb5b8bb04815b2fb80d
ToppCellControl-Epithelial_cells-Airway_club|Control / group, cell type (main and fine annotations)

ARFGEF3 PTCHD1 TRIM2 PTPRE ROS1

2.22e-06181525c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCellCOPD-Epithelial-Club|World / Disease state, Lineage and Cell class

ARFGEF3 PTCHD1 TRIM2 SCNN1G ROS1

2.54e-061865253006f4ab1eaf1eb34c10ca9f7c869603d2d25744
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IL1RAPL1 SNTG1 SCNN1G CUL9

2.35e-05143524990844ca674d30b2924c74b45bed4fdfb8463fa7
ToppCelldroplet-Lung-3m-Hematologic-myeloid-interstitial_macrophage|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CCR2 PTCHD1 PNPLA1 MPEG1

3.48e-051585249a6d9b541446a6aa9f8ed040b330dbb5c6447076
ToppCelldroplet-Lung-3m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CCR2 PTCHD1 PNPLA1 MPEG1

3.48e-051585242438713d2a7e32c647ab3384237ed614f4ec8fec
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IL1RAPL1 PIEZO2 RNF144A RFX6

3.56e-051595245ca96db4281abb5f646150ccf36adc66ab201c78
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 PTCHD1 PTPRE MPEG1

3.56e-05159524cdbccb83af6220bab300dfe56443ff69f6e2043a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IL1RAPL1 PTCHD1 PIEZO2 RNF144A

3.74e-051615241b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCelldroplet-Kidney-nan-21m-Myeloid-CD45____macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 PTCHD1 PTPRE MPEG1

4.02e-05164524d4cdcd61e8c28b3fb912cef8837cc1a49678a729
ToppCellfacs-MAT-Fat-3m-Myeloid-macrophage|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 PTCHD1 PTPRE MPEG1

4.02e-05164524b81498c3934e0d52bf0329dc745e02966f9d8613
ToppCelldroplet-Kidney-nan-21m-Myeloid-macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 PTCHD1 PTPRE MPEG1

4.12e-051655249852a4cb680af39c92c7d2d5e5fa8dc04e6602aa
ToppCelldroplet-Kidney-nan-21m-Myeloid|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 PTCHD1 PTPRE MPEG1

4.12e-05165524c629ed33ff14834c32cc1a91116fb079f7aaa94d
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ARFGEF3 PTCHD1 TRIM2 PRICKLE2

4.21e-05166524c20479fe7a4306320d7f26e78bf956225f00f35a
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-Reg_T-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PRICKLE3 CUL9 KYAT3 ZFP69

4.42e-05168524187b98664843a304406f086ea696adbf32283d07
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IL1RAPL1 PTCHD1 PIEZO2 RNF144A

4.84e-0517252408a3fe536b1b064c5ee7779bc2b1115a5963a26b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IL1RAPL1 PTCHD1 PIEZO2 RNF144A

4.84e-05172524553701349444eb366df3c11f54bb093434f153c6
ToppCellwk_15-18-Hematologic-Myeloid-pDC|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CCR2 PTPRE MPEG1 SLC9C2

4.95e-05173524b571970e3ba88afc07041c5692ccfd85fc39e796
ToppCell3'-Child04-06-SmallIntestine-Epithelial-neuro-epithelial-N_cells_(NTS+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 ARRDC4 RFX6 VWDE

4.95e-05173524f31e738c2b3b319fb40b0b16b2393a51c9a8999c
ToppCellnucseq-Epithelial-Epithelial_Airway-Secretory/RAS|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ARFGEF3 EVA1C TRIM2 SCNN1G

5.41e-05177524779ba86f53650772755b52460be03f18bb204e55
ToppCellnucseq-Epithelial-Epithelial_Airway-Secretory/RAS-Secretory|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ARFGEF3 EVA1C TRIM2 SCNN1G

5.41e-051775240f210cfb61b873c5fd77dc17eadf4d017306500e
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ARFGEF3 PTCHD1 TRIM2 PRICKLE2

5.53e-05178524f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid-pDC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCR2 PTPRE MPEG1 SLC9C2

5.53e-05178524b7d1d8f76c1c2467b1a39a9b4150ed4a47144a15
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GPR26 DIAPH2 KCNN2 KIF13A

5.65e-051795249ba8693fba2175bca9ff9735cc04e657abeb9084
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL1RAPL1 PIEZO2 PTPRE PRICKLE2

5.65e-05179524a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARFGEF3 SNTG1 RFX6 ROS1

5.77e-051805246b1606238417490e0d9930870a7827419d1c3737
ToppCellPCW_05-06-Hematologic_ErythroMegGranulo-Hem_Granulocytic-im_mast/basophil_(18)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CCR2 TRGC1 TRGC2 MPEG1

5.90e-05181524f737f2b1f35747b81fdd8996e289bde5c290af61
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_monocyte_(14)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CCR2 TRGC1 TRGC2 MPEG1

5.90e-051815243457c1d431db4282be5a6243119e48960748ede7
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

ARFGEF3 PTCHD1 TRIM2 PRICKLE2

6.42e-0518552498b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

ARFGEF3 TRIM2 SCNN1G ROS1

6.42e-05185524cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 CD19 DIAPH2 MPEG1

6.42e-051855247adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PTPRE DIAPH2 MPEG1 RFX6

6.56e-0518652423b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellEpithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|World / Lineage, Cell type, age group and donor

ARFGEF3 PTCHD1 TRIM2 ROS1

6.69e-0518752481cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IL1RAPL1 EVA1C PIEZO2 RNF144A

6.83e-0518852432f22a4d8cb98fd8b8fa0fbf28ef9266d711d081
ToppCellIPF-Epithelial-Club|IPF / Disease state, Lineage and Cell class

ARFGEF3 TRIM2 SCNN1G ROS1

6.98e-05189524f3fcef008ef252b29ac6d567fef27f9acf9cd70f
ToppCellPCW_05-06-Hematologic_ErythroMegGranulo-Hem_Granulocytic|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CCR2 TRGC1 TRGC2 MPEG1

7.12e-051905248e254fc77dd1d2d2a4ce0700af3c37829ca089bf
ToppCellCOPD-Epithelial-Club|COPD / Disease state, Lineage and Cell class

ARFGEF3 TRIM2 SCNN1G ROS1

7.27e-05191524c909cf5fa0e6519aa93a47d2c3fcd2ae2163cd8d
ToppCellChildren_(3_yrs)-Epithelial-club_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ARFGEF3 TRIM2 PRICKLE2 SCNN1G

7.27e-0519152423776c7302cead3881b39127398f3b3e0d27885e
ToppCellIPF-Epithelial-Club|World / Disease state, Lineage and Cell class

ARFGEF3 TRIM2 SCNN1G ROS1

7.27e-051915243c88a6f1d74bb3b9173cd0ea3a63c6d9570e3954
ToppCellCOPD-Epithelial|COPD / Disease state, Lineage and Cell class

ARFGEF3 TRIM2 PRICKLE2 ROS1

7.41e-051925240644fad5df18f0021f6f49cca996d8cf47f972ff
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

IL1RAPL1 ARFGEF3 PIEZO2 TRIM2

7.41e-051925243ce5dbde41aeb73d49f2c7991d34682f0827fa5a
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ARRDC4 VKORC1L1 TRGC2 GPR137B

7.56e-05193524aa679fb27f914a931e51cff7153861cde0edfd85
ToppCellnormal_Lymph_Node-T/NK_cells-CD8_low_T|T/NK_cells / Location, Cell class and cell subclass

CCR2 TRGC1 TRGC2 GPR137B

7.56e-0519352448809047d3194aff225fc43c3d5152c20434fe62
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

ARFGEF3 EVA1C TRIM2 PRICKLE2

7.87e-05195524fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ARFGEF3 TRIM2 PRICKLE2 SCNN1G

7.87e-05195524dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

ARFGEF3 EVA1C TRIM2 PRICKLE2

7.87e-05195524eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellTransverse-Dendritic_cell-Lymphoid_DC|Dendritic_cell / Region, Cell class and subclass

EVA1C PIEZO2 CD19 PRICKLE3

8.19e-051975248545baf923ddf84c5ce9414a36d810603be52401
ToppCellBLOOD--(3)_Classical_Mono-2| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CCR2 PTPRE ARRDC4 MPEG1

8.35e-0519852434c23181c227f65209cde4382248253282f6ac6e
ToppCellBiopsy_Other_PF-Epithelial-SCGB3A2+|Biopsy_Other_PF / Sample group, Lineage and Cell type

ARFGEF3 TRIM2 SCNN1G ROS1

8.68e-05200524631550dc34bcb605ab726645f4024d7828bb7975
ToppCellSevere-B_intermediate-1|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

IL1RAPL1 WASHC4 MPEG1

4.29e-0412652342a0bdbe18ef85146cac4e86b2b27d0b3b20d8a2
ToppCellMild/Remission-B_intermediate-10|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

CD19 RNF144A GPR137B

5.36e-041365231b3c6edcbe0eb674d2d9c838e83ebe2b93e3eec1
ToppCellLPS_only-Myeloid-Monocytes,_Macrophages-Erythroid|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPR137C PRICKLE3 MPEG1

5.71e-04139523d96e5c17582f1576fa09d6bad35c418b6248448c
ToppCelldroplet-Pancreas-Exocrine-18m-Hematologic-leukocyte|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 PNPLA1 MPEG1

6.07e-04142523bf4a9633d128805a0d7e426d6fe6c29db1ff8c81
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IL1RAPL1 SCNN1G CAV3

6.33e-041445235665dd2839b6c8ddbf5ddb2d22e1ee6073f74c3b
ToppCellfacs-Trachea-3m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CCR2 MPEG1 ROS1

6.33e-041445238bd042f12186f36bc5aabf6a0232270a448f4b58
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FBXO22 GPR137C SCNN1G

6.72e-041475232885978bcfc5623967c0c1204dadf5c78c74a082
ToppCelldroplet-Pancreas-Exocrine-18m-Hematologic|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 PNPLA1 MPEG1

6.72e-04147523684e2d8d2f0516cf8b0dc53efa7efc3050bbf0d1
ToppCellPND07-Immune-Immune_Myeloid-DC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCR2 PTPRE MPEG1

6.72e-04147523bbc52cbea37a38058436e3fc6fc0777f83404524
ToppCelldroplet-Pancreas-Exocrine-18m-Hematologic-leukocyte|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 PNPLA1 MPEG1

6.72e-04147523c031fad0a4e192019775809968e46da54a111d27
ToppCellPND03-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCR2 PTPRE MPEG1

6.85e-041485233f48f5ba0a0928ddf6da7a1be1976933921f42ad
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 PTCHD1 PTPRE

6.98e-0414952348fca6ae33d7722c024b43ce04f4dbce7b6b424b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IL1RAPL1 PIEZO2 RNF144A

7.12e-041505238645b9c7f9511ed6cc9afe04440c2873a3094150
ToppCelldroplet-Fat-Scat-21m-Myeloid-monocyte|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 PTPRE MPEG1

7.12e-04150523b6e5e04aaf1c5265ac07581868d3159f9292a84c
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D175|Adult / Lineage, Cell type, age group and donor

PTCHD1 KCNN2 ROS1

7.12e-04150523b0b6ba3686d3eb8a9b249d30be14111de3b893be
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SNTG1 SCNN1G ROS1

7.26e-04151523f4f7156b2c0cfc78fd1841e07c9915d97ced561f
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCR2 PTPRE MPEG1

7.40e-04152523b2e29fbda6b5f2d87cfc05423caf9cbf3b04ac65
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_4|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PTCHD1 TRIM2 CUL9

7.40e-041525236d02b50e9e9ecf820f84a79e46d153a4840a1cfe
ToppCellfacs-Aorta-Heart-24m-Myeloid-nan|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 PTPRE MPEG1

7.40e-04152523525d65c5c8e5580947367afdb1f6e68b49e9e5bb
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_4|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

PTCHD1 TRIM2 CUL9

7.40e-04152523eb7ff36792c3c54ac88cfe976f84016b70b1a1d7
ToppCellE16.5-samps-Myeloid-Fetal_macrophage-Proliferative_Myeloid|E16.5-samps / Age Group, Lineage, Cell class and subclass

CCR2 PTPRE MPEG1

7.40e-04152523e427758a6e39052616a0d8ecec0c1299e81d1d3c
ToppCellMyeloid-C_(Monocyte)|World / shred on cell class and cell subclass (v4)

CCR2 PTPRE MPEG1

7.40e-041525239145dc014ed7f154c158d454dc2b9754396afcca
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IL1RAPL1 SNTG1 SCNN1G

7.54e-041535239b6675ace8a83c8d446b722301d0ec4e6840f3fc
ToppCellE16.5-samps-Myeloid-Fetal_macrophage|E16.5-samps / Age Group, Lineage, Cell class and subclass

CCR2 PTPRE MPEG1

7.54e-04153523e9567966fe4426176e2f2dc0be4832c769c9903a
ToppCellControl-PLT_4|World / Disease Group and Platelet Clusters

GPR137C THUMPD1 RGS3

7.69e-04154523a2a03c5e6759c45aeeedf1e68ecb5a0112ef9a20
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRGC1 TRGC2 KCNN2

7.69e-04154523e94cd11488003347120eacd3ced0a8923ed09ccc
ToppCellPND03-Immune-Immune_Myeloid-DC-cDC2|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCR2 PTPRE MPEG1

7.69e-04154523c663e9834be0b45389a862dc3c13a1f988a3e5ee
ToppCellE16.5-samps-Myeloid|E16.5-samps / Age Group, Lineage, Cell class and subclass

CCR2 PTPRE MPEG1

7.98e-04156523c7c73cef5700b0ae75280e62c94728434c712537
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCR2 PTPRE MPEG1

8.13e-04157523857cd7edc872ade3f0164abefe61600c69d16f58
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IL1RAPL1 SNTG1 SCNN1G

8.13e-041575232c5295043611bac7dfa4aef2146681bce4a33a8f
ToppCelldroplet-Fat-Scat-21m-Myeloid|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 PTPRE MPEG1

8.28e-04158523c8df636412a08c570f235c34d4cff46924a9b11d
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCR2 PTPRE MPEG1

8.28e-04158523097a1b719da5c99a7db8531ab45913bd9270b497
ToppCellMonocytes-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

CCR2 PTPRE MPEG1

8.28e-04158523c3096b3a914a1a15ebe3664613e94b951f8555fc
ToppCelldroplet-Fat-Scat-21m-Myeloid-myeloid_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 PTPRE MPEG1

8.28e-04158523718eafcf8a171bb69b402dc9d69564c3521a62a9
ToppCellInt-URO-Lymphocyte-T_NK-CD8_TCM|Int-URO / Disease, Lineage and Cell Type

EVA1C TRGC2 VWDE

8.28e-04158523edcc5a26d4571b179f3ae538fed23b661e4677dd
ToppCelldroplet-Kidney-nan-18m-Lymphocytic-CD45|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 PTPRE MPEG1

8.28e-04158523e0b862e4b9ebaa12869640b5d18d5fa852861bef
ToppCellfacs-Aorta-Heart-24m-Myeloid|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 PTPRE MPEG1

8.43e-04159523443f6df4a88fa8755adcde4cc12575dff614ecb4
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARFGEF3 PTCHD1 RFX6

8.43e-041595237747cef94c55144fddcd024a7495318357f1351b
ToppCellE16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCR2 PTPRE MPEG1

8.43e-04159523dd9059f98eec43adbcc0cd42bb155670f7a3a479
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Lymphocytic-B_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD19 GPR137B FBXO47

8.43e-04159523656aa20706bdba81bbcc3e68e6058215b92b8802
ToppCelldroplet-Kidney-nan-18m-Myeloid-CD45____macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 PTPRE MPEG1

8.58e-04160523d18c4cc99a31481dd0ee8af9299695d5f6857b42
ToppCelldroplet-Kidney-nan-18m-Myeloid|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 PTPRE MPEG1

8.58e-04160523a707a4ad9fbedcca227f76b49f1393e88101c2fb
ToppCelldroplet-Kidney-nan-18m-Myeloid-macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 PTPRE MPEG1

8.58e-0416052373b604cbdcd9e8f0f317964abc632abee314a557
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR2 PTPRE MPEG1

8.58e-04160523e9e52532131cdc3fb01e81cfc046e3f670cc8e75
ToppCellE18.5-Immune-Immune_Myeloid-DC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCR2 PTPRE MPEG1

8.58e-041605239f1fec2cf565193c73cc3c8a4f0476e57478e3b8
ToppCellVE-CD8-naive_CD4|VE / Condition, Cell_class and T cell subcluster

ZNF516 ZFP69 BAHD1

8.58e-04160523255d2a150bfe19ee3d4d34533feb9c37ce73d225
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 PTPRE MOV10L1

8.74e-04161523fb59d96c2aa9e4654f02bf6ce36bf832776cb4dd
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)|Hippocampus / BrainAtlas - Mouse McCarroll V32

PTCHD1 THUMPD1 GABRQ

8.74e-0416152366554f59eaea4ba55a6c6724f9368e24e99c91e9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 PTPRE MOV10L1

8.74e-04161523c53c461fc721a7960cef86662f49e2a495520701
DiseaseAutism Spectrum Disorders

IL1RAPL1 PTCHD1 GABRQ

4.87e-0485533C1510586
Diseasemuscular dystrophy (implicated_via_orthology)

TRIM2 CAV3

6.50e-0421532DOID:9884 (implicated_via_orthology)
DiseaseMental Retardation, X-Linked

IL1RAPL1 PTCHD1

1.25e-0329532C1136249
DiseaseMental Retardation, X-Linked 1

IL1RAPL1 PTCHD1

1.52e-0332532C2931498

Protein segments in the cluster

PeptideGeneStartEntry
YKIIEECVSQIVLHC

DIAPH2

446

O60879
ILDCCIIRVDYSLAV

ARRDC4

281

Q8NCT1
IIDIFCVCDSILYKV

RFX6

311

Q8HWS3
CVCDSILYKVLTDVL

RFX6

316

Q8HWS3
FCVLYLAEKAECLFT

RGS3

631

P49796
LLVFCKTVCEDVFQV

MPEG1

441

Q2M385
SILSKFYQCEICVVD

YOD1

226

Q5VVQ6
ELRVVLVFGYNCCKV

FBXO22

216

Q8NEZ5
CVVLVDYTIRKFCIQ

PTPRE

266

P23469
CRFEEIVIDAVKPYC

MOV10L1

831

Q9BXT6
YERIFFICLEILVCA

KCNN2

211

Q9H2S1
NISCIKAIDIYILVC

GABRQ

321

Q9UN88
LFILCAISLVCYICK

GPR137C

211

Q8N3F9
FLLSFVVLCCTYLKV

GPR26

181

Q8NDV2
LVCLVTIYKCYKIEI

IL1RAPL1

371

Q9NZN1
DTSIFEKILFICCIV

OR2M3

191

Q8NG83
DTSIFEKVLFICCIV

OR2M5

191

A3KFT3
KLACIETYTLELFVI

OR4L1

186

Q8NH43
KEELIEALYCSCFVP

PNPLA1

141

Q8N8W4
IFCTLCLKQYVELLI

RNF144A

41

P50876
VCTVCNELLVDLIYF

PRICKLE2

161

Q7Z3G6
FVCTTCQELLVDLIY

PRICKLE3

216

O43900
LLRLFYCTVLVCSKE

EVA1C

31

P58658
KVSAVTLAYLIFCLC

CD19

291

P15391
LKIAEVCIETYISSC

ARFGEF3

136

Q5TH69
VACIEEKCYVLTFAE

BAHD1

701

Q8TBE0
IIFTKCQKEDSVYVC

CCR2

176

P41597
CIKSYLIEIQCISHI

CAV3

106

P56539
VVFLALVCEKELYCM

FBXO47

356

Q5MNV8
YAVVLCCLGAKEILS

CUL9

1071

Q8IWT3
CSVVCVIEIIEVFFI

SCNN1G

541

P51170
VIADLCIKYDTLCIS

KYAT3

231

Q6YP21
FLECLFCDVKLQYAV

KIF13A

796

Q9H1H9
FAVTAFCVELCLKVI

RNF139

421

Q8WU17
LFVLCAVSLSICLYK

GPR137B

201

O60478
LLKSVVYFAIITCCL

TRGC1

146

P0CF51
LLLKSVVYFAIITCC

TRGC2

161

P03986
LQCIICSEYFIEAVT

RNF8

401

O76064
LEVERIQCKTYACVL

SNTG1

391

Q9NSN8
KVELDCISVLCLIYG

PTCHD1

746

Q96NR3
FLCEVKSITFYACAI

OR5AL1

101

P0C617
AVCEECLKVYLSAQV

RNF217

281

Q8TC41
CLLCSLVKTIDQFEY

SUPT4H1

16

P63272
TIKENVCIIDGLCYV

VWDE

1051

Q8N2E2
VIVAGLSLYEVCAKC

ZNF516

326

Q92618
ICVEDIYAHIFILKC

PIEZO2

2366

Q9H5I5
CALIMKIICLEIYYV

NUP188

1036

Q5SRE5
LVDLCVDISKGCVYL

ROS1

2056

P08922
LYFVLKEFCIICIVT

VKORC1L1

131

Q8N0U8
KEFCIICIVTYVLNF

VKORC1L1

136

Q8N0U8
VLNKVITVYAALCCE

WASHC4

86

Q2M389
SCLLKREIEYTVICE

SLC9C2

951

Q5TAH2
LLCEDPVFAEYIKCI

USP34

3206

Q70CQ2
IDKQFLICSICLERY

TRIM2

16

Q9C040
QYTVVVEIIKAVCCL

THUMPD1

236

Q9NXG2
IRTKTYECNICEKIF

ZFP69

266

Q49AA0