Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessdetection of mechanical stimulus involved in sensory perception of sound

ADGRV1 HPN STRC CHRNA10 STRCP1

1.17e-06231735GO:0050910
GeneOntologyBiologicalProcessdetection of mechanical stimulus

ADGRV1 PKDREJ HPN STRC CHRNA10 STRCP1

3.98e-05751736GO:0050982
GeneOntologyBiologicalProcessinner ear development

ADGRV1 TSKU FREM2 ATG4B HPN KCNK2 ANKRD24 STRC CHRNA10 STRCP1

5.70e-0525317310GO:0048839
GeneOntologyBiologicalProcessinner ear receptor cell stereocilium organization

ADGRV1 TSKU ANKRD24 STRC STRCP1

8.12e-05531735GO:0060122
GeneOntologyBiologicalProcessdetection of external stimulus

NR2F6 ADGRV1 PKDREJ PITPNM1 HPN STRC CHRNA10 STRCP1

1.09e-041731738GO:0009581
GeneOntologyBiologicalProcessdetection of mechanical stimulus involved in sensory perception

ADGRV1 HPN STRC CHRNA10 STRCP1

1.15e-04571735GO:0050974
GeneOntologyBiologicalProcessdetection of abiotic stimulus

NR2F6 ADGRV1 PKDREJ PITPNM1 HPN STRC CHRNA10 STRCP1

1.18e-041751738GO:0009582
MousePhenoabnormal cochlear outer hair cell physiology

ADGRV1 HPN STRC CHRNA10 STRCP1

7.66e-06281405MP:0004434
DomainL_dom-like

TCTE1 LRRC75B PRAMEF10 INSRR CPN2 FBXL19 NOD2 TLR10 TSKU TRIL CMIP NOD1 IGFALS NISCH LRRC73 TPBG

8.34e-0832817516IPR032675
Domain-

TCTE1 LRRC75B PRAMEF10 CPN2 FBXL19 NOD2 TLR10 TSKU TRIL CMIP NOD1 IGFALS NISCH LRRC73 TPBG

3.73e-07321175153.80.10.10
DomainLeu-rich_rpt

TCTE1 LRRC75B CPN2 FBXL19 NOD2 TLR10 TSKU TRIL NOD1 IGFALS NISCH TPBG

9.84e-0627117512IPR001611
DomainLNS2

PITPNM2 PITPNM1 PITPNM3

1.58e-0561753IPR013209
DomainPI_transfer

PITPNM2 PITPNM1 PITPNM3

1.58e-0561753IPR001666
DomainLNS2

PITPNM2 PITPNM1 PITPNM3

1.58e-0561753SM00775
DomainDDHD

PITPNM2 PITPNM1 PITPNM3

1.58e-0561753PF02862
DomainDDHD

PITPNM2 PITPNM1 PITPNM3

1.58e-0561753PS51043
DomainDDHD_dom

PITPNM2 PITPNM1 PITPNM3

1.58e-0561753IPR004177
DomainLNS2

PITPNM2 PITPNM1 PITPNM3

1.58e-0561753PF08235
DomainLNS2/PITP

PITPNM2 PITPNM1 PITPNM3

1.58e-0561753IPR031315
DomainDDHD

PITPNM2 PITPNM1 PITPNM3

1.58e-0561753SM01127
DomainAIG1

GIMAP5 GIMAP2 GIMAP1

4.37e-0581753PF04548
DomainG_AIG1

GIMAP5 GIMAP2 GIMAP1

4.37e-0581753IPR006703
DomainG_AIG1

GIMAP5 GIMAP2 GIMAP1

4.37e-0581753PS51720
DomainHEAT_REPEAT

PDS5B CAND2 MROH2A HEATR5A MROH1 IPO13

4.96e-05701756PS50077
DomainARM-type_fold

PDS5B USP34 CAND2 MROH2A HEATR5A FOCAD IPO9 MROH1 PELP1 NBEAL2 IPO13 SYMPK

8.77e-0533917512IPR016024
DomainARM-like

PDS5B CAND2 MROH2A HEATR5A IPO9 MROH1 PELP1 NBEAL2 IPO13 SYMPK

2.38e-0427017510IPR011989
DomainPHOSPHORYLASE

PYGB PYGM

2.60e-0431752PS00102
DomainGlycg_phsphrylas

PYGB PYGM

2.60e-0431752IPR011833
DomainGlyco_trans_35

PYGB PYGM

2.60e-0431752IPR000811
DomainPhosphorylase

PYGB PYGM

2.60e-0431752PF00343
DomainNa/sul_symport_CS

SLC13A1 SLC13A5

2.60e-0431752IPR031312
DomainNA_SULFATE

SLC13A1 SLC13A5

2.60e-0431752PS01271
DomainLRR

CPN2 NOD2 TLR10 TSKU TRIL IGFALS NISCH TPBG

6.28e-042011758PS51450
DomainNa/sul_symport

SLC13A1 SLC13A5

8.57e-0451752IPR001898
DomainIP_trans

PITPNM2 PITPNM1

8.57e-0451752PF02121
DomainNa_sulph_symp

SLC13A1 SLC13A5

8.57e-0451752PF00939
DomainLRR_1

CPN2 FBXL19 TLR10 TSKU TRIL IGFALS NISCH TPBG

1.09e-032191758PF00560
DomainDynamin_central

DNM3 DNM2

1.28e-0361752IPR000375
DomainGED

DNM3 DNM2

1.28e-0361752SM00302
DomainDynamin_M

DNM3 DNM2

1.28e-0361752PF01031
DomainGED_dom

DNM3 DNM2

1.28e-0361752IPR020850
DomainGED

DNM3 DNM2

1.28e-0361752PS51388
DomainDynamin_GTPase_CS

DNM3 DNM2

1.28e-0361752IPR019762
DomainGED

DNM3 DNM2

1.28e-0361752PF02212
DomainGED

DNM3 DNM2

1.28e-0361752IPR003130
DomainCys-rich_flank_reg_C

CPN2 TLR10 TRIL IGFALS TPBG

1.58e-03901755IPR000483
DomainLRRCT

CPN2 TLR10 TRIL IGFALS TPBG

1.58e-03901755SM00082
DomainTLV_coat

ERVMER34-1 ERVS71-1

1.78e-0371752PF00429
DomainG_DYNAMIN_1

DNM3 DNM2

1.78e-0371752PS00410
DomainDYNc

DNM3 DNM2

1.78e-0371752SM00053
PathwayREACTOME_SYNTHESIS_OF_PI

PITPNM2 PITPNM1 PITPNM3

5.79e-0651193M26962
PathwayREACTOME_SYNTHESIS_OF_PI

PITPNM2 PITPNM1 PITPNM3

5.79e-0651193MM14587
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TANC2 PITPNM2 USP34 NR2F6 MYCBP2 SZT2 SPEG MED14 PIGG FBXL19 BIRC6 NOD2 FOCAD CDR2L MROH1 ADAMTSL5 PCNX4 NBEAL2 AHNAK NISCH SBF2 MCM3AP PDCD11 PYGB ZFYVE26 BCAM ABCC10 SYMPK

3.08e-1211051782835748872
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PDS5B SYNE1 SPEG HEATR5A GPATCH8 FOCAD TRIL MROH1 NISCH MCM3AP DNM3 KATNIP CHPF2 DOP1B

2.77e-084071781412693553
Pubmed

Pitpnm1 is expressed in hair cells during development but is not required for hearing.

PITPNM2 PITPNM1 PITPNM3

1.32e-073178323820044
Pubmed

Chromosomal localization, genomic organization and evolution of the genes encoding human phosphatidylinositol transfer protein membrane-associated (PITPNM) 1, 2 and 3.

PITPNM2 PITPNM1 PITPNM3

1.32e-073178315627748
Pubmed

Identification of a novel family of targets of PYK2 related to Drosophila retinal degeneration B (rdgB) protein.

PITPNM2 PITPNM1 PITPNM3

5.25e-074178310022914
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

USP34 FAM234A CYP2S1 NUP205 FOCAD TSKU CMIP MROH1 TMEM168 TMTC4 MCM3AP IPO13 TMEM192 ADGRE5 BCAM TMED10 ABCC10 MFSD3 TPBG SYMPK

5.96e-0710611782033845483
Pubmed

Defining the membrane proteome of NK cells.

LPCAT1 MYCBP2 MED14 SLU7 PIGG LTB4R2 BIRC6 SLC1A4 NUP205 NBAS IPO9 PELP1 NBEAL2 AHNAK NISCH PYGB CHPF2 ADGRE5 PTTG1IP GAA KIF2C

6.55e-0711681782119946888
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

USP34 FKBP10 FAM234A MYCBP2 ADAM15 SPTLC1 C1RL PIGG GTF3C3 TSKU COL18A1 TMEM245 IPO13 TMEM131L CHPF2 ADGRE5 CERS1 TMED10 TOR1AIP1 KIF2C SYMPK

1.02e-0612011782135696571
Pubmed

Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.

USP34 CCNI2 NR2F6 LRRC75B ADAM15 INSRR CAMSAP3 FBXL19 FOCAD COL18A1 CMIP PELP1 NBEAL2 SLC22A10 ZFYVE26 GRIN3B KIF2C

1.49e-068321781736724073
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

PDS5B USP34 MYCBP2 NUP98 BIRC6 GTF3C3 NUP205 WDR75 PELP1 AHNAK MCM3AP PDCD11 PYGB DNM2 SYMPK

1.54e-066531781522586326
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

PDS5B FKBP10 LPCAT1 FAM234A CAND2 ADAM15 SPTLC1 NUP98 GTF3C3 NUP205 IPO9 NISCH CHPF2 CERS1 TMED10 TOR1AIP1 GAA SYMPK

1.87e-069421781831073040
Pubmed

Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.

FAM234A ADAM15 SPTLC1 NUP98 C1RL NUP205 COL18A1 FBXO6 TMEM245 TMEM131L CHPF2 TMED10 GAA DNM2

3.72e-066131781422268729
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PITPNM2 USP34 CASP8AP2 CAND2 SZT2 ADGRV1 NUP205 ATG4B NBEAL2 PAN2 IPO13 PDCD11 TMEM131L

3.80e-065291781314621295
Pubmed

Functional expression of pattern recognition receptors in tissues of the human female reproductive tract.

NOD2 TLR10 NOD1

4.54e-067178319406482
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

PDS5B PTBP3 IQGAP2 MED14 ATG4B IPO9 WDR75 PELP1 IGHA1 PYGB TOR1AIP1 DNM2 SYMPK

7.01e-065601781335241646
Pubmed

Human ortholog to mouse gene imap38 encoding an ER-localizable G-protein belongs to a gene family clustered on chromosome 7q32-36.

GIMAP5 GIMAP2 GIMAP1

7.24e-068178311814688
Pubmed

Comparative analysis of the human gimap gene cluster encoding a novel GTPase family.

GIMAP5 GIMAP2 GIMAP1

1.08e-059178315474311
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

GPHN TANC2 CAND2 IQGAP2 MYCBP2 CAMSAP3 FBXL19 ARL15 NUP205 CDR2L RIN1 IPO9 AHNAK NISCH PAN2 IPO13 KATNIP TMEM102 DNM2 KIF2C

1.57e-0513211782027173435
Pubmed

Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

USP34 PCLO GPATCH8 NBEAL2 MCM3AP KATNIP

1.75e-0510517869628581
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

TANC2 PDS5B FAM234A PPFIBP2 SYNE1 SPTLC1 PIGG BIRC6 SLC1A4 RIN1 NCOA7 TMEM102 BCAM CERS1

2.22e-057191781435337019
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

USP34 CASP8AP2 MYCBP2 SYNE1 ADGRV1 BIRC6 DNM3 DOP1B

2.25e-05225178812168954
Pubmed

Synergism between TLRs and NOD1/2 in oral epithelial cells.

NOD2 NOD1

2.60e-052178218573991
Pubmed

Signalling pathways and molecular interactions of NOD1 and NOD2.

NOD2 NOD1

2.60e-052178216493424
Pubmed

Mutational analysis of human NOD1 and NOD2 NACHT domains reveals different modes of activation.

NOD2 NOD1

2.60e-052178221310790
Pubmed

TRIM50 suppressed hepatocarcinoma progression through directly targeting SNAIL for ubiquitous degradation.

TRIM50 SNAI1

2.60e-052178229789583
Pubmed

Inflammatory cytokine response to Bacillus anthracis peptidoglycan requires phagocytosis and lysosomal trafficking.

NOD2 NOD1

2.60e-052178220308305
Pubmed

NOD1 and NOD2 regulate proinflammatory and prolabor mediators in human fetal membranes and myometrium via nuclear factor-kappa B.

NOD2 NOD1

2.60e-052178223740944
Pubmed

NOD1 and NOD2 of the innate immune system is differently expressed in human clear cell renal cell carcinoma, corresponding healthy renal tissue, its vasculature and primary isolated renal tubular epithelial cells.

NOD2 NOD1

2.60e-052178230903318
Pubmed

Peptidoglycan molecular requirements allowing detection by Nod1 and Nod2.

NOD2 NOD1

2.60e-052178212871942
Pubmed

Role of Nod1 in mucosal dendritic cells during Salmonella pathogenicity island 1-independent Salmonella enterica serovar Typhimurium infection.

NOD2 NOD1

2.60e-052178219620349
Pubmed

Nucleotide oligomerization domains 1 and 2: regulation of expression and function in preadipocytes.

NOD2 NOD1

2.60e-052178218714036
Pubmed

NOD1 and NOD2 signalling links ER stress with inflammation.

NOD2 NOD1

2.60e-052178227007849
Pubmed

Association of Toll-like receptor 10 and susceptibility to Crohn's disease independent of NOD2.

NOD2 TLR10

2.60e-052178221716313
Pubmed

TRIM50 Suppresses Pancreatic Cancer Progression and Reverses the Epithelial-Mesenchymal Transition via Facilitating the Ubiquitous Degradation of Snail1.

TRIM50 SNAI1

2.60e-052178234568024
Pubmed

A Salmonella virulence factor activates the NOD1/NOD2 signaling pathway.

NOD2 NOD1

2.60e-052178222186610
Pubmed

Viral infection augments Nod1/2 signaling to potentiate lethality associated with secondary bacterial infections.

NOD2 NOD1

2.60e-052178221669398
Pubmed

Understanding the molecular differential recognition of muramyl peptide ligands by LRR domains of human NOD receptors.

NOD2 NOD1

2.60e-052178228673961
Pubmed

Implication of NOD1 and NOD2 for the differentiation of multipotent mesenchymal stem cells derived from human umbilical cord blood.

NOD2 NOD1

2.60e-052178221042538
Pubmed

LipL21 lipoprotein binding to peptidoglycan enables Leptospira interrogans to escape NOD1 and NOD2 recognition.

NOD2 NOD1

2.60e-052178229211798
Pubmed

Aggregatibacter actinomycetemcomitans outer membrane vesicles are internalized in human host cells and trigger NOD1- and NOD2-dependent NF-κB activation.

NOD2 NOD1

2.60e-052178225024364
Pubmed

The role of NOD1/CARD4 and NOD2/CARD15 genetic variations in lung cancer risk.

NOD2 NOD1

2.60e-052178226238283
Pubmed

Contribution of the NOD1/CARD4 insertion/deletion polymorphism +32656 to inflammatory bowel disease in Northern Europe.

NOD2 NOD1

2.60e-052178217285593
Pubmed

Function of Nod-like receptors in microbial recognition and host defense.

NOD2 NOD1

2.60e-052178219120480
Pubmed

Cross-tolerization between Nod1 and Nod2 signaling results in reduced refractoriness to bacterial infection in Nod2-deficient macrophages.

NOD2 NOD1

2.60e-052178218768892
Pubmed

Expression and in vitro assessment of tumorigenicity for NOD1 and NOD2 receptors in breast cancer cell lines.

NOD2 NOD1

2.60e-052178229615116
Pubmed

NOD-like receptor activation by outer membrane vesicles from Vibrio cholerae non-O1 non-O139 strains is modulated by the quorum-sensing regulator HapR.

NOD2 NOD1

2.60e-052178221263023
Pubmed

Simultaneous deletion of NOD1 and NOD2 inhibits in vitro alloresponses but does not prevent allograft rejection.

NOD2 NOD1

2.60e-052178226159289
Pubmed

The role of nucleotide-binding oligomerization domain 1 during cytokine production by macrophages in response to Mycobacterium tuberculosis infection.

NOD2 NOD1

2.60e-052178226255090
Pubmed

Endosomes as platforms for NOD-like receptor signaling.

NOD2 NOD1

2.60e-052178224832447
Pubmed

The effects of NOD activation on adipocyte differentiation.

NOD2 NOD1

2.60e-052178223712977
Pubmed

Differential function of the NACHT-LRR (NLR) members Nod1 and Nod2 in arthritis.

NOD2 NOD1

2.60e-052178218574154
Pubmed

Aberrant expression of regulatory cytokine IL-35 and pattern recognition receptor NOD2 in patients with allergic asthma.

IL12A NOD2

2.60e-052178225326182
Pubmed

Gene Variants, mRNA and NOD1/2 Protein Levels in Tunisian Childhood Asthma.

NOD2 NOD1

2.60e-052178230874883
Pubmed

Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss.

STRC STRCP1

2.60e-052178234910522
Pubmed

Association of Nucleotide-binding Oligomerization Domain Receptors with Peptic Ulcer and Gastric Cancer.

NOD2 NOD1

2.60e-052178227917621
Pubmed

Progesterone receptor-B enhances estrogen responsiveness of breast cancer cells via scaffolding PELP1- and estrogen receptor-containing transcription complexes.

PGR PELP1

2.60e-052178224469035
Pubmed

The frameshift mutation in Nod2 results in unresponsiveness not only to Nod2- but also Nod1-activating peptidoglycan agonists.

NOD2 NOD1

2.60e-052178216115863
Pubmed

Differential expression and regulation of nuclear oligomerization domain proteins NOD1 and NOD2 in human endometrium: a potential role in innate immune protection and menstruation.

NOD2 NOD1

2.60e-052178219273470
Pubmed

Role of NOD1/CARD4 and NOD2/CARD15 gene polymorphisms in cancer etiology.

NOD2 NOD1

2.60e-052178221745515
Pubmed

Influence of a nucleotide oligomerization domain 1 (NOD1) polymorphism and NOD2 mutant alleles on Crohn's disease phenotype.

NOD2 NOD1

2.60e-052178217907287
Pubmed

Activation of Nod1 and Nod2 induces innate immune responses of prostate epithelial cells.

NOD2 NOD1

2.60e-052178222228081
Pubmed

NOD1/NOD2-mediated recognition of non-typeable Haemophilus influenzae activates innate immunity during otitis media.

NOD2 NOD1

2.60e-052178231474163
Pubmed

NOD1 and NOD2 in inflammatory and infectious diseases.

NOD2 NOD1

2.60e-052178232677123
Pubmed

NOD1 and NOD2 expression and function in very preterm infant mononuclear cells.

NOD2 NOD1

2.60e-052178224444388
Pubmed

Analgesic effects of chemically synthesized NOD1 and NOD2 agonists in mice.

NOD2 NOD1

2.60e-052178220083500
Pubmed

NOD1 and NOD2 stimulation triggers innate immune responses of human periodontal ligament cells.

NOD2 NOD1

2.60e-052178222218461
Pubmed

Nucleotide-binding oligomerization domain (NOD) plays an important role in neonatal infection.

NOD2 NOD1

2.60e-052178230321637
Pubmed

Complex insertion/deletion polymorphism in NOD1 (CARD4) is not associated with inflammatory bowel disease susceptibility in East Anglia panel.

NOD2 NOD1

2.60e-052178217012967
Pubmed

Salmonella enterica serovar Typhimurium ΔmsbB triggers exacerbated inflammation in Nod2 deficient mice.

NOD2 NOD1

2.60e-052178225423082
Pubmed

Higher Expression of NOD1 and NOD2 is Associated with Vogt-Koyanagi-Harada (VKH) Syndrome But Not Behcet's Disease (BD).

NOD2 NOD1

2.60e-052178226980698
Pubmed

Identification of microRNAs involved in NOD-dependent induction of pro-inflammatory genes in pulmonary endothelial cells.

NOD2 NOD1

2.60e-052178232353008
Pubmed

Nod1 and Nod2 enhance TLR-mediated invariant NKT cell activation during bacterial infection.

NOD2 NOD1

2.60e-052178224163408
Pubmed

NOD1 and NOD2 control the invasiveness of trophoblast cells via the MAPK/p38 signaling pathway in human first-trimester pregnancy.

NOD2 NOD1

2.60e-052178225840495
Pubmed

Disruption of Nod-like receptors alters inflammatory response to infection but does not confer protection in experimental cerebral malaria.

NOD2 NOD1

2.60e-052178219407112
Pubmed

Association of NOD1 and NOD2 genes polymorphisms with Helicobacter pylori related gastric cancer in a Chinese population.

NOD2 NOD1

2.60e-052178222563200
Pubmed

NOD protein expression and function in first trimester trophoblast cells.

NOD2 NOD1

2.60e-052178217156193
Pubmed

Nod-like receptors are critical for gut-brain axis signalling in mice.

NOD2 NOD1

2.60e-052178231652348
Pubmed

Sensing of the microbiota by NOD1 in mesenchymal stromal cells regulates murine hematopoiesis.

NOD2 NOD1

2.60e-052178227799160
Pubmed

Association of NOD1 and NOD2 polymorphisms with Guillain-Barré syndrome in Northern Indian population.

NOD2 NOD1

2.60e-052178227000222
Pubmed

Nucleotide-binding oligomerization domain-1 and -2 play no role in controlling Brucella abortus infection in mice.

NOD2 NOD1

2.60e-052178222203860
Pubmed

Investigation of NOD1/CARD4 variation in inflammatory bowel disease using a haplotype-tagging strategy.

NOD2 NOD1

2.60e-052178217613538
Pubmed

NOD1 and NOD2 Genetic Variants in Association with Risk of Gastric Cancer and Its Precursors in a Chinese Population.

NOD2 NOD1

2.60e-052178225933107
Pubmed

Mutations in a new gene encoding a protein of the hair bundle cause non-syndromic deafness at the DFNB16 locus.

STRC STRCP1

2.60e-052178211687802
Pubmed

Upregulation of NOD1 and NOD2 contribute to cancer progression through the positive regulation of tumorigenicity and metastasis in human squamous cervical cancer.

NOD2 NOD1

2.60e-052178235130902
Pubmed

Effects of genetic variations in the genes encoding NOD1 and NOD2 on type 2 diabetes mellitus and insulin resistance.

NOD2 NOD1

2.60e-052178227885704
Pubmed

NOD1 and NOD2 regulation of pulmonary innate immunity to Legionella pneumophila.

NOD2 NOD1

2.60e-052178221108472
Pubmed

Convergence of innate immunity and insulin resistance as evidenced by increased nucleotide oligomerization domain (NOD) expression and signaling in monocytes from patients with type 2 diabetes.

NOD2 NOD1

2.60e-052178224018334
Pubmed

Effects of NOD-like receptors in human B lymphocytes and crosstalk between NOD1/NOD2 and Toll-like receptors.

NOD2 NOD1

2.60e-052178220844241
Pubmed

NOD1 and NOD2 receptors: integral members of the innate and adaptive immunity system.

NOD2 NOD1

2.60e-052178223901396
Pubmed

Nucleotide-binding oligomerization domain 1 mediates recognition of Clostridium difficile and induces neutrophil recruitment and protection against the pathogen.

NOD2 NOD1

2.60e-052178221411735
Pubmed

Lack of Both Nucleotide-Binding Oligomerization Domain-Containing Proteins 1 and 2 Primes T Cells for Activation-Induced Cell Death.

NOD2 NOD1

2.60e-052178228652394
Pubmed

Phenotyping of Nod1/2 double deficient mice and characterization of Nod1/2 in systemic inflammation and associated renal disease.

NOD2 NOD1

2.60e-052178223259058
Pubmed

Association of NOD1 and NOD2 Polymorphisms With Susceptibility to Subacute Sclerosing Panencephalitis.

NOD2 NOD1

2.60e-052178236544356
Pubmed

Association of interleukin-1 receptor-associated kinase M (IRAK-M) and inflammatory bowel diseases.

NOD2 IRAK3

2.60e-052178217558906
Pubmed

Nod1 and nod2 are expressed in human and murine renal tubular epithelial cells and participate in renal ischemia reperfusion injury.

NOD2 NOD1

2.60e-052178220124104
Pubmed

Immunohistochemical detection of NOD1 and NOD2 in the healthy murine and canine eye.

NOD2 NOD1

2.60e-052178219604345
Pubmed

NOD1 activators link innate immunity to insulin resistance.

NOD2 NOD1

2.60e-052178221715553
Pubmed

Variants of NOD1 and NOD2 genes display opposite associations with familial risk of Crohn's disease and anti-saccharomyces cerevisiae antibody levels.

NOD2 NOD1

2.60e-052178221739538
Pubmed

Blau syndrome polymorphisms in NOD2 identify nucleotide hydrolysis and helical domain 1 as signalling regulators.

NOD2 NOD1

2.60e-052178225093298
Pubmed

Cellular stress promotes NOD1/2-dependent inflammation via the endogenous metabolite sphingosine-1-phosphate.

NOD2 NOD1

2.60e-052178233942347
InteractionOPALIN interactions

PDS5B CAND2 PIGG CYP2S1 NUP205 MROH1 TMTC4 IPO13 ADGRE5 ATP2B3 DOP1B

1.68e-0620917011int:OPALIN
InteractionTOP3B interactions

TANC2 PITPNM2 USP34 NR2F6 MYCBP2 SZT2 SPEG MED14 PIGG FBXL19 BIRC6 NOD2 FOCAD CDR2L MROH1 ADAMTSL5 PELP1 PCNX4 NBEAL2 AHNAK NISCH SBF2 MCM3AP PDCD11 PYGB ZFYVE26 BCAM ABCC10 SYMPK

1.50e-05147017029int:TOP3B
InteractionGYPA interactions

SCFD2 PDS5B FFAR2 CYP2S1 FOCAD DNM3 TMEM192 DNM2 SYMPK

1.74e-051741709int:GYPA
InteractionNPTN interactions

PDS5B CAND2 FOCAD FBXO6 MROH1 NBEAL2 IPO13 ZFYVE26 ATP2B3 DOP1B SYMPK

2.51e-0527817011int:NPTN
Cytoband7q36.1

GIMAP5 GIMAP2 GIMAP1 CHPF2

1.99e-047417747q36.1
GeneFamilyPhosphatidylinositol transfer proteins

PITPNM2 PITPNM1 PITPNM3

5.62e-06612031151
GeneFamilyGTPases, IMAP

GIMAP5 GIMAP2 GIMAP1

1.56e-0581203580
GeneFamilyGlycogen phosphorylases

PYGB PYGM

1.30e-0431202437
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

GPHN TANC2 LPCAT1 SYNE1 CFTR ADGRV1 FREM2 NCOA7 ROS1 FAM20A

5.77e-0919317710f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

GPHN TANC2 LPCAT1 SYNE1 CFTR ADGRV1 FREM2 NCOA7 ROS1 FAM20A

5.77e-0919317710fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2|Adult / Lineage, Cell type, age group and donor

GPHN TANC2 LPCAT1 CFTR ADGRV1 FREM2 HPN ROS1 FAM20A

8.39e-081931779738f4f0a9ddde2432b429ab46838e353b1790589
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LPCAT1 SYNE1 CFTR ADGRV1 FREM2 HPN TMEM245 ROS1 FAM20A

9.57e-0819617797e5addaa844e66f8160e05858c341866a80aed23
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GPHN LPCAT1 SYNE1 CFTR ADGRV1 FREM2 HPN TMEM245 ROS1

1.09e-0719917792dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Ctxn3_Sla|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TRABD2B IQGAP2 FEZF2 CMYA5 RIN1 AHNAK KCNK2 TPBG

2.89e-0716217784d13c271b4f63cf32980e5643b5d5951165fe8b5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GPHN PTBP3 IQGAP2 CFTR INSRR ARL15 PGR DOP1B

3.32e-071651778dc570154baed59ed109e5369589448e075ba66a9
ToppCellfacs-Skin-Anagen-24m-Epithelial-bulge_keratinocyte|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRABD2B C1RL VWA7 COL18A1 HPN KCNK2 PITPNM3 FAM20A

3.64e-07167177878909f685ccd1321064eb0887caf9263e0e54879
ToppCellfacs-Skin-Anagen-24m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRABD2B C1RL VWA7 COL18A1 HPN KCNK2 FAM20A NR1I3

5.19e-0717517785552ff1e13f931c8cd7780726c90b5609497a648
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GPHN PTBP3 IQGAP2 CFTR INSRR ARL15 NCOA7 DOP1B

6.43e-071801778cfc8bfbfd3617aabbb49f9730c29b673ca157e74
ToppCellControl-Epithelial_cells-AT2|Control / group, cell type (main and fine annotations)

GPHN TANC2 LPCAT1 SYNE1 ADGRV1 FREM2 ROS1 FAM20A

6.43e-071801778198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCellCOVID-19-lung-AT2|lung / Disease (COVID-19 only), tissue and cell type

TANC2 LPCAT1 PCLO CFTR ADGRV1 FREM2 HPN ROS1

1.01e-061911778276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

GPHN TANC2 USP34 NUP98 ARL15 BIRC6 CMIP SBF2

1.09e-061931778779276e775cb2492e8dd36436295a536084a6415
ToppCellFetal_29-31_weeks-Endothelial-capillary_endothelial_cell_(Cap1)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PITPNM2 ADAM15 ESAM PLEKHG2 COL18A1 CMIP SLC22A10 FES

1.09e-061931778ad2df9b77999780860141be6ec366afc0172a331
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

GPHN TANC2 PITPNM2 SYNE1 ADGRV1 FREM2 TMEM245 ROS1

1.13e-06194177897534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TANC2 LPCAT1 CFTR ADGRV1 FREM2 HPN ROS1 FAM20A

1.32e-0619817782e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TANC2 LPCAT1 CFTR ADGRV1 FREM2 HPN ROS1 FAM20A

1.32e-061981778f948391296c261c473d339069a6d0f20ccd6f38f
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLCD3B PCLO BCAN IGSF11 ADGRV1 KCNK2 NCOA7 PYGB

1.37e-06199177847466253069d4b1b8f13ce3210f434e60753b38a
ToppCellSigmoid-(3)_ILC|Sigmoid / shred on region, Cell_type, and subtype

PITPNM2 DIPK1C DUSP2 CDR2L CDH20 FES NCOA7 IRAK3

1.42e-062001778a7326c43987a5eb4f4f5b48c4252cf4870432e5d
ToppCellSigmoid-ILC-ILC|Sigmoid / Region, Cell class and subclass

PITPNM2 DIPK1C DUSP2 CDR2L CDH20 FES NCOA7 IRAK3

1.42e-0620017784ac1e6d7f358003e2448eb69e545772cd261c55f
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Macroglial|GW19 / Sample Type, Dataset, Time_group, and Cell type.

DIPK1C LPCAT1 IQGAP2 BCAN IGSF11 SLC1A4 FREM2 SLC13A5

1.42e-0620017783a954d9d542e52c9b181f0850a09b1bff0a0c82d
ToppCellSigmoid-ILC|Sigmoid / Region, Cell class and subclass

PITPNM2 DIPK1C DUSP2 CDR2L CDH20 FES NCOA7 IRAK3

1.42e-062001778dfb06821f1019833f5d81f9c93808219b5fef407
ToppCellSigmoid-(3)_ILC-(30)_ILC|Sigmoid / shred on region, Cell_type, and subtype

PITPNM2 DIPK1C DUSP2 CDR2L CDH20 FES NCOA7 IRAK3

1.42e-062001778c39de94623383da7b2b260eb016ddaa5da7f4350
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Macroglial-Astrocyte|GW19 / Sample Type, Dataset, Time_group, and Cell type.

DIPK1C LPCAT1 IQGAP2 BCAN IGSF11 SLC1A4 FREM2 SLC13A5

1.42e-0620017787c66953ff6d8f16f4decd23c85232990d2d8c6c4
ToppCellCOVID-19_Moderate-multiplets|COVID-19_Moderate / disease group, cell group and cell class

FKBP10 SYNE1 IDO2 ADAMTSL5 IGHA1 NBEAL2 CERS1

2.07e-061471777baf15c773d7751bc6f64d4974a22738626f2b3ff
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Nfib-Inhibitory_Neuron.Gad1Gad2.Nfib-Satb1_(Supramammillary_Nucleus_(SuM))|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

IL12A MROH2A BDKRB1 FAM151A STRC

6.55e-06661775f7d1d272ae723d8100b8c252b3d894dae5297fe4
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Nfib|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

IL12A MROH2A BDKRB1 FAM151A STRC

6.55e-066617752180e189dad1347ad77733ea95a934d70be97ee4
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Nfib-Inhibitory_Neuron.Gad1Gad2.Nfib-Satb1_(Supramammillary_Nucleus_(SuM))-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

IL12A MROH2A BDKRB1 FAM151A STRC

6.55e-06661775412c95c708344fd1726351389bb8a3d376f54fe4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PTBP3 IQGAP2 INSRR ARL15 PCNX4 CYP26C1 DOP1B

6.81e-0617617776c7edf1cb38644500bce6c5a1dd90bbe17415cdb
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

LRRC75B NUP98 NBAS CDH20 TMEM168 PDCD11 MFSD3

7.07e-06177177782fdd6185b368f54f03de389427cbe3071d21a99
ToppCellfacs-Lung-EPCAM-18m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM15 ESAM ARL15 ALS2CL PGR CDR2L TRIM62

7.07e-0617717772433924dcb085ebbe2545d476ebd7ee68e6092fb
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GPHN PTBP3 IQGAP2 CFTR INSRR ARL15 NCOA7

7.33e-06178177751d2188406f04329311b2efd1108fc36617a860e
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l19|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GIMAP5 ADAM15 ESAM GIMAP1 ARL15 NOD2 BCAM

8.48e-061821777840427d1c23d60482c943ff006b14007ed44d247
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ESAM CYP2S1 ERVMER34-1 COL18A1 BCAM PTTG1IP GAA

9.43e-0618517774a188e2566a75d1b4f3c879a8c241c277c4b451c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ESAM CYP2S1 ERVMER34-1 COL18A1 BCAM PTTG1IP GAA

9.43e-0618517776da9a06e1514d5d5f47359a14637f02539846096
ToppCelldroplet-Lung-nan-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TLCD3B ADAM15 ESAM CDR2L DNM3 BCAM TPBG

1.01e-051871777b535d5447bf15e95dcf025a0a455628b956fc857
ToppCelldroplet-Lung-nan-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TLCD3B ADAM15 ESAM CDR2L DNM3 BCAM TPBG

1.01e-05187177764dd28b23eda7dfb7fd069be2742de7bad0fd87a
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LPCAT1 CFTR ADGRV1 FREM2 HPN TMEM245 ROS1

1.01e-0518717775df9e1f5ca32217af255e76e6fb5afa346337811
ToppCellCOPD-Epithelial-ATII|Epithelial / Disease state, Lineage and Cell class

GPHN TANC2 LPCAT1 CFTR FREM2 TMEM245 ROS1

1.01e-051871777030af361f8bdcd0aff4ec1922702833325cf74d8
ToppCellCOVID-19-kidney-CD-IC-B|kidney / Disease (COVID-19 only), tissue and cell type

PTBP3 IQGAP2 CFTR INSRR ARL15 PGR NCOA7

1.01e-051871777ce05b89860573fe0356102e2998d1ef6d1968034
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_naive-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FFAR2 SIRPB1 NBEAL2 AHNAK FES IRAK3 SNAI1

1.08e-05189177755aba1ebc012006a5db3ff9c92589cb3d9f7c68a
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LPCAT1 CFTR ADGRV1 FREM2 TMEM245 ROS1 FAM20A

1.16e-051911777ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

LPCAT1 PCLO CFTR ADGRV1 FREM2 HPN ROS1

1.20e-051921777cc9911e182a289779a2612bc213daae5607689e7
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D122|Adult / Lineage, Cell type, age group and donor

GPHN LPCAT1 PCLO ADGRV1 FREM2 HPN FAM20A

1.20e-05192177706013a07e3a873b1d1c0451643c528593ac32a9c
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

GPHN LPCAT1 CFTR ADGRV1 FREM2 HPN ROS1

1.20e-05192177758c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO INSRR IGFALS MROH1 FAM151A NISCH GAA

1.24e-051931777471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO INSRR IGFALS MROH1 FAM151A NISCH GAA

1.24e-051931777fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.2.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LPCAT1 CFTR HPN NCOA7 ROS1 BCAM FAM20A

1.37e-051961777784459f9f3614ead947aeb61a873dfd4cbe50641
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LPCAT1 SYNE1 CFTR FREM2 HPN ROS1 FAM20A

1.42e-051971777bf10727fbe90b71d2ac60a11711e5f0701b3799d
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW19-Macroglial-Astrocyte|GW19 / Sample Type, Dataset, Time_group, and Cell type.

DIPK1C LPCAT1 IQGAP2 BCAN IGSF11 SLC1A4 SLC13A5

1.46e-051981777bfad1c51cf884ff7ce89f8278820800582541dc7
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW19-Macroglial|GW19 / Sample Type, Dataset, Time_group, and Cell type.

DIPK1C LPCAT1 IQGAP2 BCAN IGSF11 SLC1A4 SLC13A5

1.46e-0519817776372e65242236c497d9b3be147092897c1609d22
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

GPHN USP34 ARL15 BIRC6 FOCAD NBAS SBF2

1.51e-05199177794b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

TANC2 LPCAT1 CFTR CAMSAP3 ADGRV1 HPN ROS1

1.56e-052001777e8db082aa4d0597500e4f16a5c0ea3e62c6c59ae
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal-Unfolded_protein_responsible_cell|GW12 / Sample Type, Dataset, Time_group, and Cell type.

NR2F6 IQGAP2 CFTR PIGG PLEKHG2 AHNAK CHPF2

1.56e-0520017776b7314c425f6b40f1301dd39cc02b0436e96a2ec
ToppCellBronchial-10x5prime-Epithelial-Epi_alveolar-AT2|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LPCAT1 CFTR ADGRV1 FREM2 HPN ROS1 FAM20A

1.56e-052001777b535323e18d9fb0dde1e0026df142c831e48c29f
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CYP2S1 PLEKHG2 MROH1 FES TMEM102 NME6 GAA

1.56e-05200177788d713dfc792e7609bf7ecfb28f87cb748088570
ToppCellLPS-antiTNF-Myeloid-Monocytes,_Macrophages-T-cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IQGAP2 PITPNM1 TLR10 MROH1 PYGM CHPF2

1.75e-051361776186be8e1595608004b8216892cb9c7a7f31fbb4d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 CFTR INSRR PCNX4 NCOA7 DOP1B

2.62e-051461776ec1f793409d1a81c0f9323eb3c82ffe01dae0e44
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D122|Adult / Lineage, Cell type, age group and donor

PITPNM2 LPCAT1 CAMSAP3 ADGRV1 PITPNM3 ROS1

3.93e-05157177631d1bd9138c60e8485664ec4144f987226e3eef9
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PITPNM2 DNHD1 LPCAT1 IGFALS TMEM245 ROS1

4.69e-051621776e0417f1242edf71934fe62bccc55c4678f7ff4ac
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PITPNM2 DNHD1 LPCAT1 IGFALS TMEM245 ROS1

4.69e-0516217768e0f03fcc25b2ea777e8478fbf771699cf93719c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CASP8AP2 ADAM15 ESAM GIMAP1 TRIM62 PITPNM3

4.85e-0516317761feb4ef7b8abcfca9a72c8d13c40548de79e7db2
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Adult / Lineage, Cell type, age group and donor

PITPNM2 LPCAT1 CAMSAP3 ADGRV1 PITPNM3 FAM20A

4.85e-051631776e819a1d6d28290854aa0672b3a18fa9e293d8f23
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAM234A PPFIBP2 CFTR ADGRV1 NOD2 NBEAL2

5.02e-051641776d6f71d804bb65301c02ea4e6673e20688b5fcd5b
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-double_negative_T_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUP98 RIN1 RBM15B PAN2 KATNIP PTTG1IP

5.74e-051681776de1042267407719f19eb3f580a5df0c9cd0e8273
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

FKBP10 LRRC75B IGHA1 ZFYVE26 SNAI1 BCAM

5.74e-0516817768459d0a1bf6d4b5c83001097331f8b78fceb9305
ToppCell10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like|GI_small-bowel / Manually curated celltypes from each tissue

DIPK1C AHNAK CYP26C1 FES NCOA7 IRAK3

5.74e-051681776d02eba7ece17edcdd47fd6b784c93910ce61090f
ToppCellfacs-Kidney|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GIMAP5 GIMAP1 IGSF11 SLC13A1 FAM151A HPN

5.74e-051681776d2f17a470e04f8f0edb111894027bcfc6ee1a12f
ToppCell368C-Myeloid-Macrophage-FABP4+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SCFD2 ZBTB9 OCA2 ADGRV1 DNM3 CCL23

6.33e-051711776e59afa0a773dca3b9c208d17510ea55703b42598
ToppCellBronchial_Biopsy-Endothelial-Lymphatic|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

GIMAP5 GIMAP1 SIRPB1 TRIL NOD1 EFCC1

6.54e-051721776c41f5a66781bbf63afce7ca5d118cc6d8e0fe0bc
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAND2 PCLO INSRR GRID2IP FAM151A PITPNM3

6.97e-051741776f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FKBP10 FAM234A SYNE1 CMIP TMTC4 TMEM192

7.19e-0517517761d8aab491dcc27ea5dbfb6462d18ee280b21a05e
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FKBP10 FAM234A SYNE1 CMIP TMTC4 TMEM192

7.19e-051751776427a7ee92fe16a90625946492062d37aa0f7235b
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l7|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TLCD3B GIMAP5 ESAM GIMAP1 ARL15 BCAM

7.19e-0517517767be76d39e1a4f4ac709672cd2d409a2523a083ce
ToppCelldroplet-Heart-4Chambers-18m-Hematologic-erythrocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LPCAT1 CCNDBP1 E2F2 PROX2

7.25e-0556177464bb7d3632b14452b6b861f73880b1dab729a0cf
ToppCellCV-Severe-7|CV / Virus stimulation, Condition and Cluster

LRRC75B NUP98 CDH20 TMEM168 PDCD11 MFSD3

7.42e-0517617763de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|343B / Donor, Lineage, Cell class and subclass (all cells)

CAND2 MROH1 SBF2 DENND6B TMEM131L MFSD3

7.90e-051781776ec6364432d37a32f5152d36d89f5e96dddb72a9d
ToppCellBAL-Mild-cDC_4|Mild / Compartment, Disease Groups and Clusters

ARL15 TMEM168 TMTC4 IPO13 TMEM192 MFSD3

8.15e-05179177668511e87b12b8253de7771e5ccfc5869248b8450
ToppCell5'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GIMAP5 GIMAP2 ADAM15 ESAM GIMAP1 TRIM50

8.40e-051801776af7c4b9f1a0ddd894085cf93c29a6d253a7d077c
ToppCell5'-GW_trimst-1-SmallIntestine-Endothelial|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GIMAP5 GIMAP2 ADAM15 ESAM GIMAP1 TRIM50

8.40e-051801776e35e9159f5cd9ec905b3b6e27d938158aeb9c51c
ToppCellfacs-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAM15 ESAM CDR2L DNM3 BCAM KIF2C

8.66e-05181177672c28baf4fd417ff4a7068603830d55074960144
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPFIBP2 CFTR INSRR ARL15 PCNX4 NCOA7

8.66e-05181177630729f0364f719c044712a51453e22dc2c1a232b
ToppCellfacs-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAM15 ESAM CDR2L DNM3 BCAM KIF2C

8.66e-0518117762ac4d3e8987d5a009d7908d8787e18165826202a
ToppCellfacs-Lung-3m-Endothelial-venous_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAM15 ESAM CDR2L DNM3 BCAM KIF2C

8.66e-0518117762628c7ac345eaaeecf8e34617e81948925962cb9
ToppCellControl-Epithelial_cells-Airway_club|Control / group, cell type (main and fine annotations)

CFTR ADGRV1 FREM2 NCOA7 ROS1 FAM20A

8.66e-051811776c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CAND2 ADAM15 IPO9 MROH1 DENND6B MFSD3

8.93e-051821776c98da2db197b1531204e116600ff51891e5c17af
ToppCelldroplet-Heart-4Chambers-18m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC75B IQGAP2 IGSF11 COL18A1 KCNK2 FAM20A

8.93e-0518217766fdaf3c8c3952a8f14dd7288e523ed58eb1d3517
ToppCellCOVID-19-kidney-CD-IC-B|COVID-19 / Disease (COVID-19 only), tissue and cell type

IQGAP2 CFTR INSRR ARL15 CYP26C1 NCOA7

8.93e-051821776ee6a8c356bbbdae55e4ea858337e079491f9f4aa
ToppCellCOPD-Epithelial-ATII|World / Disease state, Lineage and Cell class

SYNE1 CFTR ADGRV1 FREM2 HPN ROS1

9.20e-0518317768e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCell3'_v3-Lung-Myeloid_Dendritic-DC1|Lung / Manually curated celltypes from each tissue

ESAM CYP2S1 PGR TLR10 IDO2 GRIN3B

9.20e-051831776e4cbd39575b5a4612d9934532e3bad63286f8aa5
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-cycling_ENCC/glia|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BCAN IGSF11 ADGRV1 COL18A1 KCNK2 KIF2C

9.20e-05183177629b62dd542bc3f8df843998f577724f3818d4271
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MROH2A PCLO CFTR ADGRV1 FREM2 ROS1

9.48e-0518417762cbed6462fea2622871bb7e49b0df3d984239281
ToppCell5'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PITPNM2 GIMAP5 GIMAP2 ADAM15 ESAM TRIM50

9.48e-05184177697e97de52daaff8840f4ee76a94ba5e3f79de7ce
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MROH2A PCLO CFTR ADGRV1 FREM2 ROS1

9.48e-0518417762b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellCOVID-19-Epithelial_cells-AT2|COVID-19 / group, cell type (main and fine annotations)

LPCAT1 CFTR ADGRV1 FREM2 HPN ROS1

9.48e-051841776369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MROH2A PCLO CFTR ADGRV1 FREM2 ROS1

9.48e-051841776ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

MYCBP2 ARL15 BIRC6 NBAS TMEM131L DOP1B

9.76e-051851776a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell5'-Adult-LymphNode-Hematopoietic-T_cells-ILC3|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DIPK1C DUSP2 HPN CYP26C1 FES IRAK3

9.76e-0518517767d6954bb04368ec62b284ba6c3021a15fbdfdee6
ToppCellpdx-Tumor_cells-T0|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

COL18A1 CMIP HPN TMEM245 SLC13A5 TRIM50

9.76e-0518517761d874608aa2062024323512f68889219471b2f00
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADGRV1 TRIL FREM2 AHNAK SLC13A5 PYGM

1.01e-04186177673cf266aeecd3cc15e8cb6094588a393bca8fbe6
Diseaseautosomal recessive nonsyndromic deafness 16 (implicated_via_orthology)

STRC STRCP1

3.22e-0521682DOID:0110471 (implicated_via_orthology)
DiseaseMalignant neoplasm of breast

NR2F6 SYNE1 SPTLC1 NUP98 MED14 GIMAP1 OCA2 PANX2 ALS2CL PKDREJ PGR CDH20 TMTC4 NISCH ZFYVE26 SNAI1 TOR1AIP1

1.44e-04107416817C0006142
Diseasecentronuclear myopathy 1 (implicated_via_orthology)

DNM3 DNM2

3.19e-0451682DOID:0111223 (implicated_via_orthology)
Diseasemicrocytic anemia (implicated_via_orthology)

DNM3 DNM2

3.19e-0451682DOID:11252 (implicated_via_orthology)
DiseaseCharcot-Marie-Tooth disease dominant intermediate B (implicated_via_orthology)

DNM3 DNM2

3.19e-0451682DOID:0110197 (implicated_via_orthology)
DiseaseKohlschutter-Tonz syndrome (implicated_via_orthology)

SLC13A1 SLC13A5

3.19e-0451682DOID:0111668 (implicated_via_orthology)
Diseasereticulocyte measurement

GPHN PITPNM2 USP34 IQGAP2 E2F2 ARL15 BIRC6 NOD1 CDH20 AHNAK NISCH SBF2 TMEM131L NCOA7 HBM GAA

3.58e-04105316816EFO_0010700
Diseasecomplement C1r subcomponent measurement

C1RL IGHA1

6.64e-0471682EFO_0008090
DiseaseVaricose veins

CCNI2 ADAM15 IGSF11 ADGRV1 CMYA5 SBF2

8.61e-041931686HP_0002619
Diseasealcohol-related neurodevelopmental disorder (implicated_via_orthology)

SLC13A1 SLC13A5

8.82e-0481682DOID:0050667 (implicated_via_orthology)
Diseasepulmonary sarcoidosis (is_implicated_in)

CFTR NOD2

1.13e-0391682DOID:13406 (is_implicated_in)
Diseaseplatelet component distribution width

PDS5B IQGAP2 SYNE1 SIRPB1 VWA7 COL18A1 CRLF3 DNM3 TMEM131L PYGB ADGRE5 GAA

1.35e-0375516812EFO_0007984
DiseaseCalcium channel blocker use measurement

USP34 ARL15 CMIP SBF2 FES ABCC10

1.43e-032131686EFO_0009930
DiseaseMoyamoya disease

WNT9A SBF2 DNM3

1.53e-03401683MONDO_0016820
Diseaseendometrial carcinoma, endometriosis

PGR TLR10

1.71e-03111682EFO_0001065, EFO_1001512
Diseasecollagen disease (implicated_via_orthology)

DNM3 DNM2

2.05e-03121682DOID:854 (implicated_via_orthology)
Diseaseasthma (is_implicated_in)

CFTR NOD2 TLR10 NOD1 IRAK3

2.10e-031571685DOID:2841 (is_implicated_in)
Diseasedevelopmental and epileptic encephalopathy (implicated_via_orthology)

DNM3 DNM2

2.41e-03131682DOID:0112202 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

SLC1A4 BDKRB1 SLC13A1 SBF2 SLC13A5

2.47e-031631685DOID:1826 (implicated_via_orthology)
Diseaseuric acid measurement

USP34 INSRR ADGRV1 ARL15 BIRC6 SBF2 SLC22A10 NCOA7 PYGB PYGM

2.70e-0361016810EFO_0004761
Diseasereticulocyte count

PITPNM2 USP34 IQGAP2 E2F2 ARL15 BIRC6 NOD1 CDH20 AHNAK NISCH TMEM131L NCOA7 HBM GAA

2.71e-03104516814EFO_0007986
Diseaserevision of total hip arthroplasty

VWA7 STRCP1

2.80e-03141682EFO_0020973
DiseaseArthritis, Psoriatic

FBXL19 NOD2

2.80e-03141682C0003872
Diseaseearly cardiac repolarization measurement

MYCBP2 HBM

2.80e-03141682EFO_0004885
Diseasediabetic neuropathy (implicated_via_orthology)

INSRR BDKRB1

2.80e-03141682DOID:9743 (implicated_via_orthology)
Diseasemitochondrial DNA measurement

ZBTB9 SIRPB1 PANX2 NUP205 KCNK2 DNM3 GRIN3B

2.83e-033281687EFO_0006312
DiseaseAutosomal Recessive Centronuclear Myopathy

SPEG DNM2

3.22e-03151682C3645536
Diseasecalcium measurement

SCFD2 PITPNM2 ADAM15 CMIP IGFALS PCNX4 HPN PYGB SLC13A5 ABCC10

3.32e-0362816810EFO_0004838
Disease4-acetamidobutanoate measurement

PANX2 DENND6B

3.67e-03161682EFO_0021003
DiseaseGlycogen storage disease

PYGM GAA

4.14e-03171682cv:C0017919
Diseasephosphatidylcholine 40:6 measurement

NOD2 TMTC4

4.14e-03171682EFO_0010389
Diseasecutaneous melanoma, hair color

PPFIBP2 ADGRV1 AHNAK

5.36e-03621683EFO_0000389, EFO_0003924

Protein segments in the cluster

PeptideGeneStartEntry
IQDPQLRVLLPALSH

PRAMEF33

361

A0A0G2JMD5
PCVLISLLAPLAFHL

CHRNA10

246

Q9GZZ6
AHVNSLVLQPLLPAA

ALS2CL

21

Q60I27
HPTLPRVLLELANVS

FAM234A

461

Q9H0X4
VPDLNITACILLLPH

BDKRB1

181

P46663
LPLENPVLLDRFHAT

CCL23

36

P55773
LAEALLAPLTQAPEA

CDR2L

271

Q86X02
LAHQSPLQPLTAAAL

nan

291

Q9N2J8
LAQLPEELFHPLTSL

CPN2

181

P22792
ALQHPQLCTLPFLIL

ARL15

126

Q9NXU5
ILLLDEPSAHLDPVT

CFTR

1366

P13569
ANVLPTLPFHVLRSL

BIRC6

4206

Q9NR09
HLLPRLPHDSAQLVT

ADAM15

291

Q13444
EALAPPVRHLIATQL

ADGRE5

316

P48960
EIGFLSNLPIILHEP

ADGRV1

651

Q8WXG9
LELLPQRNPSLHVAS

CCNI2

271

Q6ZMN8
LRLLHPSPDLVSQEA

CMIP

371

Q8IY22
HNRLEALPNSLLAPL

IGFALS

491

P35858
ELQAPDLELSLPAIH

AHNAK

5116

Q09666
SSAVPANLHLLLRPV

DNHD1

1811

Q96M86
ANLHLLLRPVALALP

DNHD1

1816

Q96M86
LILHLLQEAAQRPSP

ANKRD24

261

Q8TF21
LLPAPVVLASVHELD

DENND6B

236

Q8NEG7
SVLSIDLNHLRPIPE

CASP8AP2

841

Q9UKL3
EALQIIHSAEPRLLP

CAMSAP3

461

Q9P1Y5
LPENILLELFTHVPA

FBXO6

16

Q9NRD1
RPSPAAILDALHQAL

EFCC1

556

Q9HA90
PSALTPKILDLLVHA

ATP2B3

501

Q16720
LVELQPSHLACPDVL

ATG4B

351

Q9Y4P1
PTSPLRETLVHLNLA

FBXL19

621

Q6PCT2
LLISSLSPALPAEHL

RBM15B

141

Q8NDT2
VLLNLSHDPEVGLPA

OCA2

751

Q04671
PLVTIGHIALLAPDQ

PDS5B

766

Q9NTI5
NAAQAALPLHTAPLL

NR2F6

246

P10588
QFILPALPHAIDLLR

GPHN

156

Q9NQX3
HILNLLITSLECNPP

NUP205

986

Q92621
LAPVLPLVTHFADIN

NR1I3

151

Q14994
LPLLAALVLAQAPAA

BCAN

6

Q96GW7
QLVLSALPHALLAVL

ABCC10

31

Q5T3U5
LDPVLDAHLNPSLLQ

PAN2

21

Q504Q3
HLSPDLPLAVTANLI

TCTE1

111

Q5JU00
LNHPLHISDPVILIS

FAM106C

36

P0CH98
VANLLRVVLSLHHPP

NUP98

1751

P52948
QALPTEAAILTLAPH

LPCAT1

121

Q8NF37
PAPVHILLLSLTLAD

FFAR2

41

O15552
LHQAVPLLVPLLAGL

ERVS71-1

436

P61550
LPEPLLHQTQSALSL

SBF2

311

Q86WG5
LPIHLHQISASPRDL

KATNIP

1241

O60303
QVPNVCPHSLLLELL

DOP1B

1301

Q9Y3R5
AFLTILVQPQHLLAP

ERVMER34-1

16

Q9H9K5
ENHLPAPLGTLVLTD

FREM2

751

Q5SZK8
LDLPSLVAEHLPGRQ

MCM3AP

1341

O60318
VNHLTSERDVLPPLL

KCNK2

386

O95069
LRPDSPAHVLLAALL

DUSP2

101

Q05923
EVFPLLGSILHDPNI

CYP2S1

391

Q96SQ9
SPHVLNLTLIDLPGI

DNM3

126

Q9UQ16
GLPPILVHSDLVLTN

IDO2

136

Q6ZQW0
PAAAAATALHLHPLL

GPATCH8

1471

Q9UKJ3
ITIPPEPLALDNIHL

PCLO

2696

Q9Y6V0
HPLLLRNLTVQAAEP

PCNX4

1141

Q63HM2
NAPEVLLASLANPVL

PCDHGC5

346

Q9Y5F6
DFQPVLHLVALNSPL

COL18A1

1576

P39060
SHIQLDSLPEVPLLV

CRLF3

136

Q8IUI8
EPAHPLVLLANLLSG

NOD1

306

Q9Y239
VAFLNPVDPISHDLL

LRRC75B

76

Q2VPJ9
PVDPISHDLLVNLAR

LRRC75B

81

Q2VPJ9
AHLLPENVSALPATV

MANSC1

216

Q9H8J5
FCHPLNLIDIVSVLP

KCNS1

301

Q96KK3
LDHLSLARNLPVATP

IL12A

16

P29459
LSAHTLLFDLPPALL

IRAK3

11

Q9Y616
QDHIPLAALPLLATS

PITPNM2

506

Q9BZ72
LAPLLLHLQDPQATV

MROH1

1496

Q8NDA8
EALLTHLLSDISPPA

PELP1

456

Q8IZL8
HLLSDISPPADALKL

PELP1

461

Q8IZL8
SPHVLNLTLIDLPGI

DNM2

126

P50570
FPLLLLDHGVSAPEL

MFSD3

236

Q96ES6
DLLPHRLAILSNFPE

NBAS

751

A2RRP1
PTSHDLLLQVLLQEP

ADAMTSL5

286

Q6ZMM2
NDIALVHLSSPLPLT

HPN

256

P05981
NPFPVLHLIEDLRLA

PPFIBP2

46

Q8ND30
HRLVTTDLPPQLANL

MED14

201

O60244
ILTHSALNILLLPSP

MED14

1176

O60244
LSAPGPHVLLLVIQL

GIMAP5

106

Q96F15
HPVAASLPLLAGTLL

ALPI

506

P09923
ILLSPQPQICSHLAE

PROX2

6

Q3B8N5
VPILPLNHALLAART

PGR

306

P06401
LLSAPGPHALLLVTQ

GIMAP1

106

Q8WWP7
IPPQASLVFHVLLID

FKBP10

246

Q96AY3
SPLAPLLLLSLHGVA

IGSF11

6

Q5DX21
LLPPLCHQDDLLILS

HEATR5A

711

Q86XA9
PAHLAQLLLFAPDAD

GRID2IP

931

A4D2P6
TDSLLELPHPLLQQT

E2F2

371

Q14209
LSAPGPHVLLLVTQL

GIMAP2

101

Q9UG22
VPTLASPLEQLRHLA

CCNDBP1

11

O95273
IHLQIAEPAALRPSL

FAM151A

411

Q8WW52
HLPILIADSGQPVLS

CDH20

571

Q9HBT6
ELILPLLAASSPEHV

CMYA5

561

Q8N3K9
HLLPPPSEELALNEL

IGHA1

231

P01876
ALLELQHSIPLGPNV

C1RL

341

Q9NZP8
EHAHLAPPELLLLAL

CERS1

51

P27544
TSLVLLLLQHPAAIA

CYP26C1

306

Q6V0L0
SALAPPSRAQLQLHL

ESAM

21

Q96AP7
TLPAPLDTINVHLRA

GAA

806

P10253
PHLRDVALPALGAVL

INSRR

121

P14616
VLQPFLPSILDGLIH

IPO9

556

Q96P70
SPLADLHALVLRVDP

HBM

81

Q6B0K9
LHALVLRVDPANFPL

HBM

86

Q6B0K9
LLLLAVLLAAHPDAQ

BCAM

16

P50895
LLHCLLPQLSSPRLA

CAND2

176

O75155
LFLPILSPLAEAIHV

SLC13A1

496

Q9BZW2
HAVPPAAITLILSLL

SLC13A5

441

Q86YT5
LPLVLHALGNPELSV

IPO13

531

O94829
VAAINPELLQLLPLH

KIF2C

61

Q99661
AVIPAPAFLLLAHLL

FOCAD

446

Q5VW36
LLQDLSPHVLPVLGS

DIPK1C

201

Q0P6D2
PAALAAHPKLFLLEN

FEZF2

201

Q8TBJ5
AEPLTILSRNATHPL

PANX2

611

Q96RD6
HPQLLLNLVDSPITA

MROH2A

791

A6NES4
PSIPLLIDHLLSTQQ

FES

521

P07332
ALAPRLPHNLSLELV

GRIN3B

61

O60391
LPHNLSLELVVAAPP

GRIN3B

66

O60391
GTLELPTPLIAAHQL

SZT2

3096

Q5T011
SLALCQLPAHPALVQ

SERGEF

396

Q9UGK8
LLPLQLPRAIHHAAT

RIN1

156

Q13671
NSDHIILILLEPIPF

TLR10

721

Q9BXR5
TIHLEDLAPHLDPLA

SYNE1

4836

Q8NF91
NVTLPHHLLPLCADV

TMEM131L

846

A2VDJ0
HAVNLLQAVAALAPP

LTB4R2

241

Q9NPC1
EVLPVLRPHSALLEN

NCOA7

771

Q8NI08
LALALAPDLAQAPLA

RIPPLY1

16

Q0D2K3
LIPHILLENFAAAIP

SLC22A10

31

Q63ZE4
LLLPTANISDVDPAH

IQGAP2

476

Q13576
SVLLPLLHNDLNPTF

PKDREJ

1766

Q9NTG1
LLEDQLSPVLTEPHL

FAM20A

481

Q96MK3
ESLQNADHLPPILLL

NBEAL2

186

Q6ZNJ1
PLLNVAVASLHPLTD

TANC2

706

Q9HCD6
HSPTILEALEGNLPL

MYCBP2

2216

O75592
LFPLLPQDVHLLNSA

SCFD2

176

Q8WU76
LNIPELLFATDRLHP

SCFD2

666

Q8WU76
LQPPALRLHDFLVTL

STRC

86

Q7RTU9
RAPEQLLALTPLHQA

STRC

1286

Q7RTU9
VPSELPDAHLGVLFL

L3HYPDH

81

Q96EM0
LPPLLAAAAIEALNI

SPTLC1

341

O15269
LVHLNILEPLNPLLT

GTF3C3

396

Q9Y5Q9
LVLPLLVAEAAAAPA

CHPF2

491

Q9P2E5
HEAALAPTAPLLVAL

SIRPB1

361

O00241
LSRSQDHIPLAALPL

PITPNM1

506

O00562
DHIPLAALPLLATSS

PITPNM1

511

O00562
LEVAVLPHNIRAFLP

PDCD11

651

Q14690
PRASLLAALLFAVHP

TMTC4

146

Q5T4D3
DQAHLLAAIPPPEIL

SNAI1

36

O95863
DPLLDAQLLPHHSLQ

TMEM192

21

Q8IY95
SHPRSQPAILLLTAA

TOR1AIP1

401

Q5JTV8
ALSADVPPALLRHLF

NOD2

616

Q9HC29
IQLNDTHPSLAIPEL

PYGM

336

P11217
AHPESRSLAVLAPLQ

SPEG

961

Q15772
PRLVLAISFHLPINS

TMED10

26

P49755
SPHLLLPDSLSQLEE

TRABD2B

406

A6NFA1
LPLTENIPAISELLH

WDR75

721

Q8IWA0
EAIGLPTHDLPLILA

SLC1A4

436

P43007
QLPTALLEPLHSLEA

TRIL

291

Q7L0X0
LPCLEHVSLLNNPLS

NISCH

401

Q9Y2I1
PLLQAHAAAQALLRP

TMEM102

381

Q8N9M5
IQLNDTHPALSIPEL

PYGB

336

P11216
ALIKPDAVAHPLILE

NME6

16

O75414
IQDPQLRVLLPALSH

PRAMEF10

361

O60809
HLDAPPAELLLAQTE

SLU7

381

O95391
ALLLLLIPVAAAQEP

PTTG1IP

21

P53801
AISHLALIPETPLRQ

ROS1

1596

P08922
LLPPEHVQELNLRST

TMEM168

431

Q9H0V1
LVTNLNPDLITPHGL

PTBP3

361

O95758
QDHVPLAALPLLAIS

PITPNM3

211

Q9BZ71
ALSPLNPGELLIALH

SYMPK

936

Q92797
PLDALPAHLLVASGL

ZBTB9

111

Q96C00
HTPIVLAALLLPLCF

TMEM245

116

Q9H330
ILPLTLEPEAAAQAH

WNT9A

41

O14904
VPLAIPAHVNLGAAL

TLCD3B

226

Q71RH2
LQPPALRLHDFLVTL

STRCP1

86

A6NGW2
LPSLRQLDLSHNPLA

TPBG

141

Q13641
HRIPANAPLSLSQEL

PLEKHG2

1121

Q9H7P9
LDPVPLRHLLNLVSA

USP34

436

Q70CQ2
LVLLAALLFRPHNLP

PIGG

801

Q5H8A4
EALLLHLPALQSVSV

TSKU

296

Q8WUA8
LKLDPATAHPLLELS

TRIM50

296

Q86XT4
LSALQLALLHTPPLS

VWA7

396

Q9Y334
LFQDIHPVPAALTLD

TRIM62

286

Q9BVG3
LLLITSADLHPEPHL

ZFYVE26

581

Q68DK2
NPALALHPALVALDL

LRRC73

106

Q5JTD7