Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsphingomyelin synthase activity

SGMS2 SGMS1

5.68e-063282GO:0033188
GeneOntologyMolecularFunctionceramide phosphoethanolamine synthase activity

SGMS2 SGMS1

5.68e-063282GO:0002950
GeneOntologyMolecularFunctionceramide cholinephosphotransferase activity

SGMS2 SGMS1

5.68e-063282GO:0047493
GeneOntologyMolecularFunctionprotein phosphatase activator activity

PPP4R3B PPP4R3A

2.55e-0417282GO:0072542
GeneOntologyMolecularFunctionphosphatase activator activity

PPP4R3B PPP4R3A

3.55e-0420282GO:0019211
GeneOntologyMolecularFunctionphosphotransferase activity, for other substituted phosphate groups

SGMS2 SGMS1

4.30e-0422282GO:0016780
GeneOntologyBiologicalProcessmeiosis I

FANCD2 CNTD1 MSH4 KNL1

4.44e-05147284GO:0007127
GeneOntologyBiologicalProcessmeiosis I cell cycle process

FANCD2 CNTD1 MSH4 KNL1

5.46e-05155284GO:0061982
GeneOntologyBiologicalProcesssphingomyelin biosynthetic process

SGMS2 SGMS1

9.70e-0511282GO:0006686
GeneOntologyBiologicalProcessreciprocal meiotic recombination

FANCD2 CNTD1 MSH4

1.01e-0467283GO:0007131
GeneOntologyBiologicalProcessreciprocal homologous recombination

FANCD2 CNTD1 MSH4

1.01e-0467283GO:0140527
GeneOntologyBiologicalProcesshomologous recombination

FANCD2 CNTD1 MSH4

1.36e-0474283GO:0035825
GeneOntologyBiologicalProcesshomologous chromosome segregation

FANCD2 MSH4 KNL1

1.59e-0478283GO:0045143
GeneOntologyBiologicalProcessmeiotic nuclear division

FANCD2 CNTD1 MSH4 KNL1

2.94e-04240284GO:0140013
GeneOntologyBiologicalProcesspositive regulation of cell cycle checkpoint

TTI2 KNL1

3.00e-0419282GO:1901978
GeneOntologyBiologicalProcesssphingomyelin metabolic process

SGMS2 SGMS1

3.67e-0421282GO:0006684
GeneOntologyBiologicalProcessmeiotic cell cycle process

FANCD2 CNTD1 MSH4 KNL1

4.46e-04268284GO:1903046
GeneOntologyBiologicalProcessmeiotic chromosome segregation

FANCD2 MSH4 KNL1

5.94e-04122283GO:0045132
GeneOntologyBiologicalProcesspositive regulation of gluconeogenesis

PPP4R3B PPP4R3A

8.60e-0432282GO:0045722
GeneOntologyCellularComponentprotein phosphatase 4 complex

PPP4R3B PPP4R3A

2.59e-056282GO:0030289
DomainDUF625

PPP4R3B PPP4R3A

2.01e-062272IPR006887
DomainSMK-1

PPP4R3B PPP4R3A

2.01e-062272PF04802
DomainPAP2_C

SGMS2 SGMS1

6.03e-063272PF14360
DomainSphingomyelin_synth-like_dom

SGMS2 SGMS1

6.03e-063272IPR025749
DomainWH1

PPP4R3B PPP4R3A

1.55e-0413272PS50229
DomainP_Acid_Pase_2/haloperoxidase

SGMS2 SGMS1

3.76e-0420272IPR000326
DomainPAP2

SGMS2 SGMS1

3.76e-0420272PF01569
DomainARM-type_fold

PPP4R3B UNC79 PPP4R3A TTI2

1.35e-03339274IPR016024
DomainARM-like

PPP4R3B PPP4R3A TTI2

6.76e-03270273IPR011989
PathwayWP_METABOLISM_OF_SPHINGOLIPIDS_IN_ER_AND_GOLGI_APPARATUS

SGMS2 SGMS1

5.25e-0421232M39459
PathwayWP_SYNTHESIS_OF_CERAMIDES_AND_1DEOXYCERAMIDES

SGMS2 SGMS1

5.77e-0422232M45544
PathwayWP_SPHINGOLIPID_METABOLISM_OVERVIEW

SGMS2 SGMS1

7.47e-0425232MM15931
PathwayWP_SPHINGOLIPID_METABOLISM_INTEGRATED_PATHWAY

SGMS2 SGMS1

8.08e-0426232M39784
PathwayWP_SPHINGOLIPID_METABOLISM_INTEGRATED_PATHWAY

SGMS2 SGMS1

8.08e-0426232MM15892
PathwayWP_SPHINGOLIPID_METABOLISM_OVERVIEW

SGMS2 SGMS1

8.72e-0427232M39863
PathwayREACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS

SGMS2 SGMS1

8.72e-0427232MM14646
PathwayWP_SPHINGOLIPID_PATHWAY

SGMS2 SGMS1

1.08e-0330232M39501
Pubmed

Sphingomyelin generated by sphingomyelin synthase 1 is involved in attachment and infection with Japanese encephalitis virus.

SGMS2 SGMS1

6.25e-07228227892528
Pubmed

SMS overexpression and knockdown: impact on cellular sphingomyelin and diacylglycerol metabolism, and cell apoptosis.

SGMS2 SGMS1

6.25e-07228217982138
Pubmed

2-Hydroxy-oleic acid does not activate sphingomyelin synthase activity.

SGMS2 SGMS1

6.25e-07228230305392
Pubmed

Sphingomyelin synthases regulate protein trafficking and secretion.

SGMS2 SGMS1

6.25e-07228221980337
Pubmed

An inositolphosphorylceramide synthase is involved in regulation of plant programmed cell death associated with defense in Arabidopsis.

SGMS2 SGMS1

6.25e-07228219001565
Pubmed

Deficiency of sphingomyelin synthase 1 but not sphingomyelin synthase 2 reduces bone formation due to impaired osteoblast differentiation.

SGMS2 SGMS1

6.25e-07228231847800
Pubmed

Chlamydia trachomatis-infected human cells convert ceramide to sphingomyelin without sphingomyelin synthases 1 and 2.

SGMS2 SGMS1

6.25e-07228231596951
Pubmed

Loss of SMEK, a novel, conserved protein, suppresses MEK1 null cell polarity, chemotaxis, and gene expression defects.

PPP4R3B PPP4R3A

6.25e-07228216107728
Pubmed

Differential localization of sphingomyelin synthase isoforms in neurons regulates sphingomyelin cluster formation.

SGMS2 SGMS1

6.25e-07228222209789
Pubmed

Both sphingomyelin synthases SMS1 and SMS2 are required for sphingomyelin homeostasis and growth in human HeLa cells.

SGMS2 SGMS1

6.25e-07228217449912
Pubmed

Sphingomyelin and sphingomyelin synthase (SMS) in the malignant transformation of glioma cells and in 2-hydroxyoleic acid therapy.

SGMS2 SGMS1

6.25e-07228222106271
Pubmed

Deficiency of sphingomyelin synthase-1 but not sphingomyelin synthase-2 causes hearing impairments in mice.

SGMS2 SGMS1

6.25e-07228222641779
Pubmed

Inhibition of sphingomyelin synthase (SMS) affects intracellular sphingomyelin accumulation and plasma membrane lipid organization.

SGMS2 SGMS1

6.25e-07228217616479
Pubmed

Carboxyl-terminal Tail-mediated Homodimerizations of Sphingomyelin Synthases Are Responsible for Efficient Export from the Endoplasmic Reticulum.

SGMS2 SGMS1

6.25e-07228227927984
Pubmed

The domain responsible for sphingomyelin synthase (SMS) activity.

SGMS2 SGMS1

6.25e-07228218694848
Pubmed

Effect of liver total sphingomyelin synthase deficiency on plasma lipid metabolism.

SGMS2 SGMS1

6.25e-07228233545384
Pubmed

Sphingomyelin synthases 1 and 2 exhibit phosphatidylcholine phospholipase C activity.

SGMS2 SGMS1

6.25e-07228234774525
Pubmed

Sphingomyelin synthases regulate production of diacylglycerol at the Golgi.

SGMS2 SGMS1

6.25e-07228218370930
Pubmed

Adenovirus-mediated overexpression of sphingomyelin synthases 1 and 2 increases the atherogenic potential in mice.

SGMS2 SGMS1

6.25e-07228216508036
Pubmed

All members in the sphingomyelin synthase gene family have ceramide phosphoethanolamine synthase activity.

SGMS2 SGMS1

1.87e-06328225605874
Pubmed

Sphingomyelin synthase-related protein SMSr is a phosphatidylethanolamine phospholipase C that promotes nonalcoholic fatty liver disease.

SGMS2 SGMS1

1.87e-06328237586586
Pubmed

Identification of a family of animal sphingomyelin synthases.

SGMS2 SGMS1

1.87e-06328214685263
Pubmed

Sphingomyelin maintains the cutaneous barrier via regulation of the STAT3 pathway.

SGMS2 SGMS1

1.87e-06328235230716
Pubmed

Impact of sphingomyelin synthase 1 deficiency on sphingolipid metabolism and atherosclerosis in mice.

SGMS2 SGMS1

1.87e-06328222580896
Pubmed

Suppressor of MEK null (SMEK)/protein phosphatase 4 catalytic subunit (PP4C) is a key regulator of hepatic gluconeogenesis.

PPP4R3B PPP4R3A

3.75e-06428220876121
Pubmed

SMS regulates the expression and function of P-gp and MRP2 in Caco-2 cells.

SGMS2 SGMS1

3.75e-06428227394416
Pubmed

Smek promotes histone deacetylation to suppress transcription of Wnt target gene brachyury in pluripotent embryonic stem cells.

PPP4R3B PPP4R3A

3.75e-06428221423269
Pubmed

Regulation of cell migration by sphingomyelin synthases: sphingomyelin in lipid rafts decreases responsiveness to signaling by the CXCL12/CXCR4 pathway.

SGMS2 SGMS1

3.75e-06428222688512
Pubmed

Modulation of ceramide metabolism in mouse primary macrophages.

SGMS2 SGMS1

3.75e-06428220637730
Pubmed

SMS2 deficiency impairs PKCδ-regulated B cell tolerance in the germinal center.

SGMS2 SGMS1

6.24e-06528234469734
Pubmed

A PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replication.

PPP4R3B PPP4R3A

1.74e-05828218614045
Pubmed

Smek promotes corticogenesis through regulating Mbd3's stability and Mbd3/NuRD complex recruitment to genes associated with neurogenesis.

PPP4R3B PPP4R3A

2.24e-05928228467410
Pubmed

Smek1/2 is a nuclear chaperone and cofactor for cleaved Wnt receptor Ryk, regulating cortical neurogenesis.

PPP4R3B PPP4R3A

4.10e-051228229180410
Pubmed

A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity.

PPP4R3B PPP4R3A

9.49e-051828216085932
Pubmed

PP4R4/KIAA1622 forms a novel stable cytosolic complex with phosphoprotein phosphatase 4.

PPP4R3B PPP4R3A

1.18e-042028218715871
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

FANCD2 PPP4R3B NOP14 NUP155 PPP4R3A KNL1

1.58e-04104928627880917
Pubmed

Morphology-based mammalian stem cell tests reveal potential developmental toxicity of donepezil.

SGMS2 SGMS1

2.17e-042728225269881
Pubmed

Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development.

SGMS2 SGMS1

2.17e-042728223096701
Pubmed

Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets.

FANCD2 MSH4 TTI2

2.72e-0415728330686591
Pubmed

Defining the membrane proteome of NK cells.

ABCC4 ATG9A NOP14 SGMS1 NUP155 AQR

2.83e-04116828619946888
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

PPP4R3B NUP155 AQR PPP4R3A

4.07e-0444028434244565
Pubmed

Transcription Factor CTIP1/ BCL11A Regulates Epidermal Differentiation and Lipid Metabolism During Skin Development.

SGMS2 SGMS1

4.09e-043728229044125
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

ABCC4 ATG9A PDE8A NUP155

6.77e-0450428434432599
Cytoband14q32.12

UNC79 PPP4R3A

1.44e-042928214q32.12
Cytoband15q14

AQR KNL1

4.14e-044928215q14
Cytoband11p15.4

OR52H1 OR52L1

6.63e-0320028211p15.4
GeneFamilyOlfactory receptors, family 52

OR52H1 OR52L1

8.43e-0449162165
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC4 SGMS2 SGMS1 ST3GAL6

4.92e-06182284ef65b095f4240d61cfd4a59aec19d72d324dba1d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC4 SGMS2 SGMS1 ST3GAL6

4.92e-0618228497a805783a1f2b055c21307db250e3688674eff3
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC4 SGMS2 SGMS1 ST3GAL6

5.36e-0618628465e25a9dcef5fc71510aaf170e220deef5b2feb2
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC4 SGMS2 SGMS1 ST3GAL6

5.36e-06186284ba6ba75218efc26371cea24ddbb0e9b3e3f421ac
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC4 SGMS2 SGMS1 ST3GAL6

5.36e-06186284e4f1259725160719e5fd13d76e5a707efed70013
ToppCelldroplet-Spleen-SPLEEN-30m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPC7 UNC79 KNL1 SORCS1

5.95e-06191284c8b99bd3a30c81ee4deba9cbf0196920ab3ab550
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Papillary|TCGA-Stomach / Sample_Type by Project: Shred V9

ZNF69 LRRC52 GADL1

5.09e-05115283f02675a5ee12cb35535f82433d7f3f3e8349a677
ToppCellMild/Remission-B_naive-1|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

PPP4R3B PPP4R3A EIF3CL

9.72e-05143283bd3f5fbd4e9e4dc414682db5607494f3ce988deb
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 ST3GAL6 SORCS1

1.46e-0416428357301178e420983c0cb72178e288a3a0449fdda3
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_1|COVID-19_Mild / Disease condition and Cell class

PPP4R3B PPP4R3A EIF3CL

1.48e-04165283ef709c5d3231c65d351316e1e31b9c9eba721628
ToppCellControl-B_intermediate-1|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

PPP4R3B PPP4R3A EIF3CL

1.54e-04167283948504367ecf58144d9dd74d2ec531358fc4b309
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Col23a1_Adamts2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FANCD2 NELL2 TRPC7

1.56e-041682833fe432267656aff81b6d92c18d1b6fc0cde73d6a
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_1|Classical_Monocyte / Disease condition and Cell class

PPP4R3B PPP4R3A EIF3CL

1.56e-04168283d50078614f7af74dc2aa4081c1708a5156ac51cf
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 ST3GAL6 SORCS1

1.68e-04172283bc3ed05fdd94d5e1f19285aea867b1453292baec
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FANCD2 GADL1 SORCS1

1.82e-0417728359cf56c385c324f0844f20003d2b5049a2791e45
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 UNC79 SORCS1

1.82e-041772830417460bdb012bc43d7254377fa53d79cdab3f34
ToppCellwk_15-18-Epithelial-PNS-COL20A1+_Schwann|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

NELL2 UNC79 SORCS1

1.82e-04177283b8cc6a7abf83a9844a5293b6cc4b19135b51fd53
ToppCellwk_08-11-Epithelial-PNS-FGFBP2+_Neural_progenitor|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

NELL2 ST3GAL6 SORCS1

1.82e-0417728315a5c96ea840376e54933ebe7a8334a11d9ce411
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP-neuro_SCP_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

NELL2 ST3GAL6 SORCS1

1.95e-04181283fad7ba168f541ac9d04edebc206f191e48bb7e99
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 ST3GAL6 SORCS1

1.95e-04181283a436e7e4c36403257ea90160a58ca0d6d7c0cdfc
ToppCellCOVID-19_Mild-CD4+_T_activated|COVID-19_Mild / Disease condition and Cell class

PPP4R3B PPP4R3A EIF3CL

1.98e-04182283877b6e611626628e709568747512f2827ebb2795
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 ST3GAL6 SORCS1

1.98e-04182283d6740bca2b974122b8451989365a94a81140afd1
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC79 LRRC52 SORCS1

1.98e-0418228382ca6d5ed48b4c487ce00b9309255abb8f20b61d
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC79 LRRC52 SORCS1

1.98e-04182283d568a8aec7e27ce632e248baea2ccd0e8dd255ac
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC79 LRRC52 SORCS1

1.98e-04182283e89cc30db8e5c77a8bbddd1d5a4b5af09f1ccd67
ToppCellPND10-Immune-Immune_Myeloid-Dendritic-cDC1|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FANCD2 NUP155 KNL1

2.01e-04183283ab38264daddccdf5ffb75ff2210b27423eca6bc0
ToppCellPND10-Immune-Immune_Myeloid-Dendritic|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FANCD2 NUP155 KNL1

2.01e-04183283e4911601dca2c0ecb448cdb6b222dedfc0c8bf6c
ToppCellCOVID-19_Mild-NK_activated|COVID-19_Mild / Disease condition and Cell class

PPP4R3B PPP4R3A EIF3CL

2.01e-0418328322bd05135906d0ecc4ba8c2e0a666093d1bf3b8f
ToppCellPND10-Immune-Immune_Myeloid-Dendritic-cDC1-cDC1_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FANCD2 NUP155 KNL1

2.01e-04183283263bfa1d8a7314bc3156c735c403c3bab8ea4dac
ToppCellControl-Neu_4|World / 5 Neutrophil clusters in COVID-19 patients

FANCD2 AQR KNL1

2.04e-04184283ce7f044956613118ee2e9fb6af2455c3166cb414
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

NELL2 MSH4 PDE8A

2.04e-04184283d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCellwk_08-11-Epithelial-PNS-COL20A1+_Schwann|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

NELL2 ST3GAL6 SORCS1

2.08e-04185283abec2a49fe0f0fa4cba49347207a1ee317333657
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC4 SGMS1 ST3GAL6

2.08e-04185283956fb0043c0c3e4e5c4d6f58ff95faf6209c380e
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC4 SGMS1 ST3GAL6

2.08e-041852837f46ea82a663181957f88e4e83114aef8a78820c
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

NELL2 ST3GAL6 SORCS1

2.08e-0418528356c7a0dbf141728ac76b8c90af197719942ca67c
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPC7 UNC79 GADL1

2.11e-04186283bdc87e4631a8ea73e262e541aa84a28f24c94b00
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC4 SGMS1 ST3GAL6

2.11e-04186283a58c9d1567da0961e0e295a156773d2252ee5a1a
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP-neuro_proliferating_SCP1_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

NELL2 ST3GAL6 SORCS1

2.11e-041862833113c85d0ac5fc46532c19b1bb71f34b985e1276
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC4 SGMS1 ST3GAL6

2.14e-04187283965584ee44669a72866a20ddf7f657bc5a7f7a8b
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC4 SGMS1 ST3GAL6

2.14e-04187283a7ef179e6561e17cafae10e1843bf82ac3ae0c89
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC4 SGMS1 ST3GAL6

2.14e-041872833e25c15fa29f8c738044914e8b3420d5713f18d9
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC4 SGMS1 ST3GAL6

2.18e-041882834dc89c7843ebd078e3414e835c56f11fa27f0c5f
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC4 SGMS1 ST3GAL6

2.18e-04188283d577b3c2a844e3062c7ca9e9ebc1722d0ac95caa
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC4 SGMS1 ST3GAL6

2.18e-041882831e788b60dd643bf220d8dfafa82d85fd083cbc71
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GDPD4 ABCC4 GADL1

2.21e-04189283aba941ba6ce7702418b3f470bde573d123c4aade
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTD1 UNC79 SORCS1

2.25e-04190283ff3dec5b45c6ea9b5319fb51a0198c6773b7be26
ToppCellwk_08-11-Epithelial-PNS-Schwann_precursor|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

NELL2 ST3GAL6 SORCS1

2.25e-041902834a777d8aa19cadd3b61b023772df142421a89113
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTD1 UNC79 SORCS1

2.25e-041902834971857eac9af17d66d673ed2ab7072639f60a10
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC4 SGMS1 ST3GAL6

2.32e-04192283a116db7dec495e5a0ba9c7537057cd1e567d7885
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC4 SGMS1 ST3GAL6

2.32e-04192283042391162df2e3d0027688dd14163c4c6821afe0
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC4 SGMS1 ST3GAL6

2.32e-041922839ae05db5bfb8b9d3935c0328e6f2d489d2b1ebfd
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC4 SGMS1 ST3GAL6

2.32e-0419228366defad13bd8e79319741e43ddb056841710b1d7
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GDPD4 ABCC4 GADL1

2.32e-04192283e0412964a3ee1bf3c0ef64f9a6f20f7e7835701e
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC4 SGMS1 ST3GAL6

2.32e-0419228371b0bfee0461ff64cef35881db3959c517e9731b
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GDPD4 ABCC4 GADL1

2.32e-04192283690cf19e9b0b2ada80097c63eae827529aa5b6f3
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC4 SGMS1 ST3GAL6

2.32e-041922839d53b42cdb537b30233cdfdc08052c8b13a1113f
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GDPD4 ABCC4 GADL1

2.32e-04192283b5871247a5f3e970fa05b33fff21bef9d2ab5741
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GDPD4 ABCC4 GADL1

2.32e-041922833d6c4c5847ca1e44fa380403d25af45d5b51ee9b
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC4 SGMS1 ST3GAL6

2.35e-041932831772f2ac217727de63c4a9303881b3a19a6bb0f0
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 ST3GAL6 SORCS1

2.35e-04193283d5930f7bd9b299f792212d40a3272a37adf64a82
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC4 SGMS1 ST3GAL6

2.35e-04193283e4b440d50ae7391b26924778be6d9d53e0692449
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC4 SGMS1 ST3GAL6

2.35e-04193283e523dc5751f6fdcd4fc1a62b1eecd43f6ae79da9
ToppCellControl-Neu_4|Control / 5 Neutrophil clusters in COVID-19 patients

FANCD2 AQR KNL1

2.46e-04196283b8b7b54ca17a08fa775507bb22b1c7248ada8f40
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 ST3GAL6 SORCS1

2.46e-04196283eea354bdaf4c558df6a94ec4f2f817f7073821d9
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 ST3GAL6 SORCS1

2.50e-041972831018aac22659c081d227d566afa29b1748c18ade
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 ST3GAL6 SORCS1

2.50e-04197283bb35a2b7320fda92e9cd42f536b7bd54e3a73a32
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-cycling_ENCC/glia|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 ST3GAL6 KNL1

2.50e-04197283cd7e34318b4ae72b7b312fda8cc0e041c2ac4ab5
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 ST3GAL6 SORCS1

2.54e-041982835b9a7b9f53a3d9cf8d6e6a7c1c94514b22cf9fa8
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 ST3GAL6 SORCS1

2.54e-04198283c8272ac4d90f2367f538f66db40de911ad73ea7f
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 ST3GAL6 SORCS1

2.54e-041982836e314dc820db9c53fe7fc7c96bed4d7d9a325160
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 ST3GAL6 SORCS1

2.54e-0419828350dfe6efca76ea9683a19b6bff59cb5030d346f1
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 ST3GAL6 SORCS1

2.57e-041992838d13a9ea87f685b5a34b84c4571db6be753cf2d9
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 ST3GAL6 SORCS1

2.57e-04199283f1d5808ccb1d5d4e2d34f864e705e2484000e88f
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 ST3GAL6 SORCS1

2.57e-04199283ce699726ac4825c65bf934cb9a76202ad7340596
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 ST3GAL6 SORCS1

2.57e-041992831761669ec514fdb4175042f11b9a31fa5687fc2b
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 ST3GAL6 SORCS1

2.57e-04199283a816b0eed80530113b7e720bbd2311a544ed8ed1
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 ST3GAL6 SORCS1

2.57e-04199283a76aa30fb264bdcbc0cb09113f814fc5a89e7319
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature-cycling_ENCC/glia|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 ST3GAL6 SORCS1

2.57e-041992839940f347973bf976ee23fb4b1cf1f349d96c21df
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 ST3GAL6 SORCS1

2.57e-041992835f350d9c7da9ac111bf22623dd4fed7f7983c9fc
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Stem_cells-Neuroepithelial_cell|GW23 / Sample Type, Dataset, Time_group, and Cell type.

FANCD2 SGMS2 KNL1

2.61e-04200283c9c832f489629b8724501ddfede984b41a7b674d
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Stem_cells|GW23 / Sample Type, Dataset, Time_group, and Cell type.

FANCD2 SGMS2 KNL1

2.61e-04200283d7832ab1ed0ff0a6f7e3ac11b2095dc72c90af44
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 ST3GAL6 SORCS1

2.61e-04200283363a8cebf2ace820661bcb87c7941f6671f8e5f3
ToppCell(53)_Lymphoid_DC|World / shred on Cell_type and subtype

ABCC4 NELL2 ST3GAL6

2.93e-0420828330212cfacad94a7cc562a69efa73a31259851515
ToppCellClub-club-6|World / Class top

NELL2 ST3GAL6

1.06e-03772823653cf20b1b312578a54ffd33e75a8b92874f9bf
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Rgs5Acta2.Cnn1_(Mural.Rgs5Acta2.Cnn1)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

CNTD1 KNL1

1.78e-03100282f6359e4b3926ce5f0980c994d7271f0743ce4c41
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Rgs5Acta2.Cnn1_(Mural.Rgs5Acta2.Cnn1)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

CNTD1 KNL1

1.78e-031002825bbcb307adf73cb8a496773f014d5cf2b36f446c
ToppCellSmart-seq2-thymus_(Smart-seq2)-hematologic|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

GADL1 SORCS1

1.96e-031052820c53fbd6ae1e3ba0216b4f5d89a129e90f002429
ToppCellSmart-seq2-thymus_(Smart-seq2)-hematologic-erythrocytic|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

GADL1 SORCS1

1.96e-03105282199d83f97517a5c794c772c57bb97653dc1d5911
ToppCellSmart-seq2-thymus_(Smart-seq2)-hematologic-erythrocytic-erythrocyte|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

GADL1 SORCS1

1.96e-0310528231cc5668d7a354bc6b7507e3ccb5338611bd162d
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Papillary-5|TCGA-Stomach / Sample_Type by Project: Shred V9

ZNF69 LRRC52

2.19e-03111282eb737146969b70c619649f244998d4183237c763
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-1|TCGA-Breast / Sample_Type by Project: Shred V9

GDPD4 CNTD1

2.23e-03112282518b7ab98b988b23f3d0f0e1f4fe90a7068f9d87
ToppCelldroplet-Mammary_Gland-nan-3m-Mesenchymal-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSH4 NOP14

2.26e-03113282ec4b89e727e1b921b9cb17443774955b95814dd4
ToppCell343B-Lymphocytic-NK_cells-NK_cell_B1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ATG9A EIF3CL

2.47e-03118282c351e465ece4f3767b2c19e695eca3c263c68777
ToppCellTCGA-Thymus-Primary_Tumor-Thymoma-Type_B3-5|TCGA-Thymus / Sample_Type by Project: Shred V9

TRPC7 SERPINA7

2.55e-031202829d4e630e1d3b9adf94a1884071bfe46edaa3f0c1
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_VISp_Col8a1_Rprm|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FANCD2 ABCC4

2.55e-031202822b7596946f9268c4202348adf3069decd8313bb0
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

FANCD2 MSH4

2.63e-0312228237612ad087d9c11d4a3466244ab36224de31930b
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-Tfh|GI_small-bowel / Manually curated celltypes from each tissue

NELL2 UNC79

2.80e-03126282d0d3e25e4fb074a76313fc90d8c3828b1d8ea486
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

KNL1 GADL1

2.80e-031262826cb89754010d64875e115da6c5805efac7a4a82d
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KNL1 GADL1

2.80e-0312628269b2525b92d1c7c35b21cc701f5fa52a9c1b94bb
ToppCelldroplet-Heart-nan-18m-Endothelial-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC4 SGMS1

2.80e-03126282de09142c12fd2ad6ecc3e7707015582f751eb426
Diseaseblood N-acetylcarnosine measurement

ABCC4 GADL1

1.82e-057282EFO_0022217
DiseaseX-12244--N-acetylcarnosine measurement

ABCC4 GADL1

1.82e-057282EFO_0021299
DiseaseN-acetylcarnosine measurement

ABCC4 GADL1

2.42e-058282EFO_0022101
DiseaseBipolar I disorder

TRPC7 GADL1

4.75e-0511282C0853193
Diseasecarnitine measurement

MSH4 SERPINA7

2.37e-0376282EFO_0010469
Diseasepuberty onset measurement

TRPC7 UNC79

6.26e-03125282EFO_0005677
Diseaseserum metabolite measurement

ABCC4 PDE8A OR52L1 GADL1

1.16e-02945284EFO_0005653

Protein segments in the cluster

PeptideGeneStartEntry
NTILDDSHLLVHCYL

AQR

271

O60306
LVLELLTFCVEHHTY

PPP4R3A

511

Q6IN85
HLILHIDCNKIYERV

NELL2

161

Q99435
VLACFLDKHHDIIII

PDE8A

116

O60658
LVVHHCRLLGEEIEY

KNL1

2231

Q8NG31
CITHLDHKDYIFLLL

LRRC52

236

Q8N7C0
ELYLHLCHKILILLV

GDPD4

61

Q6W3E5
LILELLTFCVEHHTY

PPP4R3B

546

Q5MIZ7
DLTVIDKLVVHLYHL

NOP14

491

P78316
LHLLDCIHVLLIRYV

NUP155

1321

O75694
LTFCTLILAILHHLY

ABCC4

141

O15439
LHINLELLECVYLVS

EIF3CL

676

B5ME19
ICIHKRELTELDIYH

ATG9A

196

Q7Z3C6
HKLLELCRDVIHYSV

GADL1

96

Q6ZQY3
HATCLTLLDLVYLLH

CNTD1

206

Q8N815
QLHALLCIYLEHTES

FANCD2

1181

Q9BXW9
CILLYLIVVEHSLHE

OR52H1

51

Q8NGJ2
AVLLVHAHEIGYIVC

OR52L1

101

Q8NGH7
IIAITLAFYICHEVH

ST3GAL6

261

Q9Y274
VCKLLSEIYEHIHCL

MSH4

596

O15457
AGIICILVAHEHYTI

SGMS2

261

Q8NHU3
YTPEHHLIQAVLLCL

TTI2

301

Q6NXR4
YLVLLVLGLHATIHC

SERPINA7

6

P05543
CILLAHDHYTVDVVV

SGMS1

321

Q86VZ5
CLSLYLIHERIHTGE

ZNF69

231

Q9UC07
VLYLHVTCPLEHVHL

SORCS1

881

Q8WY21
AAHCQEYEIVHILLL

TRPC7

171

Q9HCX4
YRDCDISKILLHLIH

UNC79

1411

Q9P2D8