Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	structural constituent of postsynaptic density	MAGI2 DLG1 DLG3	4.38e-05	11	131	3	GO:0098919
GeneOntologyMolecularFunction	structural constituent of postsynaptic specialization	MAGI2 DLG1 DLG3	7.52e-05	13	131	3	GO:0098879
GeneOntologyMolecularFunction	ATP hydrolysis activity	KIF27 DYNC2H1 ABCB6 RNF213 NLRP1 DHX9 NAV2 ACIN1 MACF1 CHD6 ABCD2	1.59e-04	441	131	11	GO:0016887
GeneOntologyMolecularFunction	actin binding	ESPN MYLK CFL1 SPTB ESPNL NEB SYNE2 MACF1 AFDN UTRN EPB41L2	3.23e-04	479	131	11	GO:0003779
GeneOntologyMolecularFunction	phosphatase binding	CFL1 AMBRA1 MAGI3 MAGI2 PPP3R1 DLG1 DLG3 SOD1	3.58e-04	264	131	8	GO:0019902
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	GPHN FLT3 HK1 MYLK POLE SPEG GRK5 TUT7 MAGI3 MAP3K12 CDKL5 KSR1 POLR3B CLK3 DLG1 POLD3	4.32e-04	938	131	16	GO:0016772
GeneOntologyMolecularFunction	ATP-dependent activity	KIF27 DYNC2H1 ABCB6 RNF213 NLRP1 ZNFX1 DHX9 NAV2 ACIN1 MACF1 CHD6 ABCD2	7.31e-04	614	131	12	GO:0140657
GeneOntologyMolecularFunction	actin filament binding	ESPN CFL1 SPTB ESPNL NEB MACF1 AFDN	7.58e-04	227	131	7	GO:0051015
GeneOntologyMolecularFunction	RNA polymerase binding	UVSSA RPRD1B DHX9 WDHD1	8.79e-04	65	131	4	GO:0070063
GeneOntologyCellularComponent	postsynaptic specialization, intracellular component	GPHN CFL1 CDKL5 DLG1 DLG3	2.65e-05	56	131	5	GO:0099091
GeneOntologyCellularComponent	nuclear speck	SART3 THOC7 SRSF4 SRSF6 GRK5 RBM39 SNW1 CLK3 ACIN1 AFDN SDCBP2	8.71e-05	431	131	11	GO:0016607
GeneOntologyCellularComponent	ASAP complex	SART3 ACIN1	2.32e-04	4	131	2	GO:0061574
GeneOntologyCellularComponent	SOSS complex	NABP1 NABP2	2.32e-04	4	131	2	GO:0070876
GeneOntologyCellularComponent	tight junction	CYTH1 MAGI3 MAGI2 DLG1 DLG3 AFDN	2.45e-04	139	131	6	GO:0070160
GeneOntologyCellularComponent	postsynaptic density, intracellular component	CFL1 CDKL5 DLG1 DLG3	2.51e-04	49	131	4	GO:0099092
GeneOntologyCellularComponent	neuron to neuron synapse	GPHN SYN3 CFL1 ADGRB3 MAGI2 CDKL5 PPP3R1 DLG1 MACF1 DLG3 AFDN	4.61e-04	523	131	11	GO:0098984
GeneOntologyCellularComponent	apical junction complex	CYTH1 MAGI3 MAGI2 DLG1 DLG3 AFDN	4.87e-04	158	131	6	GO:0043296
GeneOntologyCellularComponent	nuclear body	SART3 THOC7 SRSF4 SRSF6 GRK5 RBM39 DHX9 CTCFL SNW1 CLK3 CHFR ACIN1 AFDN SDCBP2 REXO1L1P	5.41e-04	903	131	15	GO:0016604
GeneOntologyCellularComponent	postsynaptic density	GPHN SYN3 CFL1 ADGRB3 MAGI2 CDKL5 DLG1 MACF1 DLG3 AFDN	5.59e-04	451	131	10	GO:0014069
GeneOntologyCellularComponent	NLRP1 inflammasome complex	CASP4 NLRP1	5.75e-04	6	131	2	GO:0072558
GeneOntologyCellularComponent	asymmetric synapse	GPHN SYN3 CFL1 ADGRB3 MAGI2 CDKL5 DLG1 MACF1 DLG3 AFDN	8.59e-04	477	131	10	GO:0032279
GeneOntologyCellularComponent	nuclear chromosome	RBBP7 POLE RGS12 DHX9 WDHD1 NCAPD2 POLD3	1.12e-03	254	131	7	GO:0000228
GeneOntologyCellularComponent	postsynaptic specialization	GPHN SYN3 CFL1 ADGRB3 MAGI2 CDKL5 DLG1 MACF1 DLG3 AFDN	1.28e-03	503	131	10	GO:0099572
GeneOntologyCellularComponent	spectrin	SPTB EPB41L2	1.36e-03	9	131	2	GO:0008091
GeneOntologyCellularComponent	bicellular tight junction	CYTH1 MAGI3 MAGI2 DLG1 DLG3	1.42e-03	131	131	5	GO:0005923
GeneOntologyCellularComponent	actin-based cell projection	ESPN CFL1 ESPNL OSBPL3 SYNE2 DLG1 UTRN	1.88e-03	278	131	7	GO:0098858
GeneOntologyCellularComponent	aggresome	TRIM73 TRIM50 TRIM74	2.01e-03	40	131	3	GO:0016235
MousePheno	hypochlorhydria	TRIM73 TRIM50 TRIM74	1.33e-05	7	103	3	MP:0008001
Domain	Guanylate_kinase_CS	MAGI3 MAGI2 DLG1 DLG3	3.38e-06	16	126	4	IPR020590
Domain	PDZ	MAGI3 RGS12 MAGI2 DLG1 DLG3 AFDN SDCBP2 PREX1	7.34e-06	148	126	8	SM00228
Domain	-	MAGI3 RGS12 MAGI2 DLG1 DLG3 AFDN SDCBP2 PREX1	8.10e-06	150	126	8	2.30.42.10
Domain	PDZ	MAGI3 RGS12 MAGI2 DLG1 DLG3 AFDN SDCBP2 PREX1	8.51e-06	151	126	8	PS50106
Domain	PDZ	MAGI3 RGS12 MAGI2 DLG1 DLG3 AFDN SDCBP2 PREX1	8.93e-06	152	126	8	IPR001478
Domain	Spectrin	SPTB SYNE2 MACF1 UTRN	1.58e-05	23	126	4	PF00435
Domain	ACTININ_2	SPTB SYNE2 MACF1 UTRN	1.58e-05	23	126	4	PS00020
Domain	ACTININ_1	SPTB SYNE2 MACF1 UTRN	1.58e-05	23	126	4	PS00019
Domain	Actinin_actin-bd_CS	SPTB SYNE2 MACF1 UTRN	1.58e-05	23	126	4	IPR001589
Domain	GUANYLATE_KINASE_2	MAGI3 MAGI2 DLG1 DLG3	1.58e-05	23	126	4	PS50052
Domain	GUANYLATE_KINASE_1	MAGI3 MAGI2 DLG1 DLG3	1.58e-05	23	126	4	PS00856
Domain	Guanylate_kin	MAGI3 MAGI2 DLG1 DLG3	2.63e-05	26	126	4	PF00625
Domain	GK/Ca_channel_bsu	MAGI3 MAGI2 DLG1 DLG3	2.63e-05	26	126	4	IPR008145
Domain	Guanylate_kin-like_dom	MAGI3 MAGI2 DLG1 DLG3	2.63e-05	26	126	4	IPR008144
Domain	GuKc	MAGI3 MAGI2 DLG1 DLG3	2.63e-05	26	126	4	SM00072
Domain	Spectrin_repeat	SPTB SYNE2 MACF1 UTRN	4.12e-05	29	126	4	IPR002017
Domain	PDZ	MAGI3 RGS12 MAGI2 DLG1 DLG3 AFDN SDCBP2	4.81e-05	141	126	7	PF00595
Domain	SPEC	SPTB SYNE2 MACF1 UTRN	6.13e-05	32	126	4	SM00150
Domain	Spectrin/alpha-actinin	SPTB SYNE2 MACF1 UTRN	6.13e-05	32	126	4	IPR018159
Domain	CH	SPTB SYNE2 NAV2 MACF1 UTRN	7.71e-05	65	126	5	SM00033
Domain	CH	SPTB SYNE2 NAV2 MACF1 UTRN	1.10e-04	70	126	5	PF00307
Domain	-	SPTB SYNE2 NAV2 MACF1 UTRN	1.18e-04	71	126	5	1.10.418.10
Domain	CH	SPTB SYNE2 NAV2 MACF1 UTRN	1.34e-04	73	126	5	PS50021
Domain	CH-domain	SPTB SYNE2 NAV2 MACF1 UTRN	1.53e-04	75	126	5	IPR001715
Domain	MAGUK_N_PEST	DLG1 DLG3	2.69e-04	4	126	2	PF10608
Domain	PDZ_assoc	DLG1 DLG3	2.69e-04	4	126	2	PF10600
Domain	DLG1_PEST_dom	DLG1 DLG3	2.69e-04	4	126	2	IPR019590
Domain	PDZ_assoc	DLG1 DLG3	2.69e-04	4	126	2	IPR019583
Domain	MAGUK_N_PEST	DLG1 DLG3	2.69e-04	4	126	2	SM01277
Domain	DLG1	DLG1 DLG3	2.69e-04	4	126	2	IPR016313
Domain	ZF_RING_2	MYCBP2 TRIM73 RNF213 TTC3 CHFR TRIM50 MEX3B TRIM74	9.45e-04	298	126	8	PS50089
Domain	RING	MYCBP2 TRIM73 RNF213 TTC3 CHFR TRIM50 MEX3B TRIM74	1.10e-03	305	126	8	SM00184
Domain	zf-RING_UBOX	TRIM73 TRIM50 TRIM74	1.54e-03	34	126	3	PF13445
Domain	Znf-RING_LisH	TRIM73 TRIM50 TRIM74	1.54e-03	34	126	3	IPR027370
Domain	Znf_RING	MYCBP2 TRIM73 RNF213 TTC3 CHFR TRIM50 MEX3B TRIM74	1.67e-03	326	126	8	IPR001841
Domain	P-loop_NTPase	KIF27 DYNC2H1 ABCB6 RNF213 MAGI3 NLRP1 ZNFX1 DHX9 MAGI2 NAV2 DLG1 DLG3 CHD6 ABCD2	1.75e-03	848	126	14	IPR027417
Domain	ZF_BBOX	MYCBP2 TRIM73 TRIM50 TRIM74	2.10e-03	80	126	4	PS50119
Domain	Znf_B-box	MYCBP2 TRIM73 TRIM50 TRIM74	2.20e-03	81	126	4	IPR000315
Domain	tRNA_anti-codon	NABP1 NABP2	2.85e-03	12	126	2	PF01336
Domain	NA-bd_OB_tRNA	NABP1 NABP2	2.85e-03	12	126	2	IPR004365
Domain	AAA	DYNC2H1 ABCB6 RNF213 NAV2 ABCD2	2.94e-03	144	126	5	SM00382
Domain	AAA+_ATPase	DYNC2H1 ABCB6 RNF213 NAV2 ABCD2	2.94e-03	144	126	5	IPR003593
Domain	ZF_RING_1	MYCBP2 TRIM73 TTC3 CHFR TRIM50 MEX3B TRIM74	3.62e-03	291	126	7	PS00518
Domain	WW	MAGI3 MAGI2 UTRN	3.92e-03	47	126	3	PF00397
Domain	zf-C3HC4	TRIM73 RNF213 TTC3 CHFR TRIM50 TRIM74	4.07e-03	223	126	6	PF00097
Domain	WW	MAGI3 MAGI2 UTRN	4.16e-03	48	126	3	SM00456
Domain	-	CYTH1 CYTH4	4.48e-03	15	126	2	1.10.1000.11
Domain	Sec7	CYTH1 CYTH4	4.48e-03	15	126	2	PF01369
Domain	Sec7_alpha_orthog	CYTH1 CYTH4	4.48e-03	15	126	2	IPR023394
Domain	WW_DOMAIN_1	MAGI3 MAGI2 UTRN	4.93e-03	51	126	3	PS01159
Domain	WW_DOMAIN_2	MAGI3 MAGI2 UTRN	4.93e-03	51	126	3	PS50020
Domain	SEC7	CYTH1 CYTH4	5.09e-03	16	126	2	PS50190
Domain	Sec7	CYTH1 CYTH4	5.09e-03	16	126	2	SM00222
Domain	Sec7_dom	CYTH1 CYTH4	5.09e-03	16	126	2	IPR000904
Domain	WW_dom	MAGI3 MAGI2 UTRN	5.21e-03	52	126	3	IPR001202
Domain	Znf_C3HC4_RING-type	TRIM73 RNF213 TTC3 TRIM50 TRIM74	6.24e-03	172	126	5	IPR018957
Domain	-	SART3 SRSF4 SRSF6 TMEM63B RBM39 ACIN1	6.26e-03	244	126	6	3.30.70.330
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	SART3 HK1 SRSF6 MYCBP2 CFL1 POLE TUT7 ACOT7 AMBRA1 RBM39 ELAC2 DHX9 POLR3B SNW1 PNPLA6 ADSL NCAPD2 ACIN1 MACF1 AFDN POLD3 DHRS2 ZNF281 UTRN EPB41L2 RPL11	7.95e-12	1353	132	26	29467282
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	PDXDC1 SART3 KIAA0930 SRSF4 SRSF6 MYCBP2 WDR33 CFL1 POLE CASP4 ELAC2 DHX9 PSMD6 MAGI2 CLK3 OSBPL3 UBAC1 ACIN1 DLG3 AFDN PREX1 EPB41L2	3.28e-09	1284	132	22	17353931
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	SART3 HK1 SRSF4 MYCBP2 RBBP7 POLE TUT7 RBM39 SNW1 SYNE2 NCAPD2 ACIN1 MACF1 AFDN UTRN EPB41L2	4.18e-09	653	132	16	22586326
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	GPHN SART3 HK1 SYN3 RBBP7 CFL1 SPTB ACOT7 ZNFX1 RBM39 DHX9 PSMD6 MAGI2 CDKL5 PNPLA6 DLG1 MACF1 DLG3 AFDN UTRN EPB41L2 RPL11 SOD1	4.60e-09	1431	132	23	37142655
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	GPHN AKAP8 MYCBP2 CFL1 CYTH1 ADGRB3 ZNFX1 TTC3 MAGI2 SNW1 NFATC3 DNAJA4 OSBPL3 SYNE2 DLG1 MACF1 DLG3 AFDN EPB41L2	4.61e-09	963	132	19	28671696
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	GPHN KIAA0930 AKAP8 MYCBP2 RBBP7 MAGI3 RGS12 KSR1 NFATC3 CLK3 OSBPL3 SYNE2 NAV2 MACF1 AFDN UTRN MEX3B EPB41L2	5.01e-09	861	132	18	36931259
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	SART3 SRSF4 AKAP8 SRSF6 WDR33 TUT7 ZNFX1 RBM39 ELAC2 DHX9 SNW1 CLK3 ACIN1 MACF1 MTO1 MEX3B RPL11	1.24e-08	807	132	17	22681889
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	SART3 MYCBP2 DYNC2H1 RPRD1B MSRA MAGI2 CLK3 SYNE2 ACIN1 DLG1 MACF1 MEX3B	1.36e-08	358	132	12	32460013
Pubmed	Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.	SRSF4 SRSF6 MYCBP2 RBBP7 RPRD1B CDKL5 SNW1 OSBPL3 ACIN1 DLG1 EPB41L2 RPL11	1.49e-08	361	132	12	30344098
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	PDXDC1 GPHN SART3 SRSF4 AKAP8 RBBP7 POLE ACOT7 RANBP6 AMBRA1 DUSP19 PSMD6 SNW1 ADSL OSBPL3 DLG1 AFDN UTRN	3.29e-08	974	132	18	28675297
Pubmed	DBIRD complex integrates alternative mRNA splicing with RNA polymerase II transcript elongation.	SRSF4 AKAP8 SRSF6 WDR33 DHX9 ACIN1 AFDN	5.14e-08	89	132	7	22446626
Pubmed	Gene structure variation in segmental duplication block C of human chromosome 7q 11.23 during primate evolution.	TRIM73 TRIM50 TRIM74	5.34e-08	3	132	3	26196062
Pubmed	TRIM50 protein regulates vesicular trafficking for acid secretion in gastric parietal cells.	TRIM73 TRIM50 TRIM74	5.34e-08	3	132	3	22872646
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	SART3 HK1 SRSF4 AKAP8 MYCBP2 RBBP7 CFL1 ACOT7 RBM39 DHX9 PSMD6 NCAPD2 MACF1 AFDN POLD3 CTSB EPB41L2 RPL11 SOD1	7.57e-08	1149	132	19	35446349
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	PDXDC1 AKAP8 MYCBP2 DYNC2H1 POLE RANBP6 AMBRA1 PSMD6 TRAFD1 PNPLA6 NCAPD2 POLD3 MTO1 CTSB	8.52e-08	606	132	14	36538041
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	MYCBP2 CYTH1 SPTB ADGRB3 MAGI3 ZNFX1 TTC3 MAGI2 POLR3B PPP3R1 NABP2 DLG1 MACF1 AFDN CHD6 CTSB UTRN PREX1 PLXNB3 SOD1	8.85e-08	1285	132	20	35914814
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	PDXDC1 GPHN SART3 HK1 SRSF6 RBBP7 CFL1 ACOT7 RANBP6 ELAC2 RPRD1B DHX9 PSMD6 ADSL WDHD1 NCAPD2 GMDS MACF1 POLD3 EPB41L2 RPL11	1.43e-07	1455	132	21	22863883
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	THOC7 HK1 SRSF4 AKAP8 SRSF6 MYCBP2 WDR33 CYTH1 ZKSCAN8 RBM39 DHX9 SNW1 CLK3 ACIN1 MACF1 CHD6 ZNF281 RPL11	1.58e-07	1082	132	18	38697112
Pubmed	Exome sequencing in seven families and gene-based association studies indicate genetic heterogeneity and suggest possible candidates for fibromuscular dysplasia.	MYLK DYNC2H1 RNF213	2.13e-07	4	132	3	26147384
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	PDXDC1 HK1 SRSF4 MYCBP2 WDR33 POLE TUT7 RANBP6 RNF213 CHML TTC3 RBM39 ELAC2 DHX9 PSMD6 ADSL OSBPL3 SYNE2 MALSU1 MTO1 CTSB	2.27e-07	1496	132	21	32877691
Pubmed	Quantifying domain-ligand affinities and specificities by high-throughput holdup assay.	MAGI3 RGS12 MAGI2 DLG1 DLG3	2.50e-07	36	132	5	26053890
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	PDXDC1 HK1 AKAP8 SRSF6 MYCBP2 RBBP7 CFL1 POLE AMBRA1 RBM39 ELAC2 DHX9 PSMD6 TRAFD1 SNW1 ADSL GMDS POLD3 RPL11	3.00e-07	1257	132	19	37317656
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	SRSF4 KIF27 AKAP8 SRSF6 RBBP7 WDR33 POLE RBM39 DHX9 SNW1 NCAPD2 ACIN1 MACF1	3.70e-07	582	132	13	20467437
Pubmed	Induced chromosome deletions cause hypersociability and other features of Williams-Beuren syndrome in mice.	TRIM73 TRIM50 TRIM74	5.31e-07	5	132	3	20049703
Pubmed	Williams-Beuren syndrome TRIM50 encodes an E3 ubiquitin ligase.	TRIM73 TRIM50 TRIM74	5.31e-07	5	132	3	18398435
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	ESPN SART3 HK1 MYLK WDR33 CFL1 GRK5 MAGI3 NEB TTC3 DNAJA4 SYNE2 NCAPD2 NAV2 ACIN1 DLG1 MACF1 DLG3 CHD6 PREX1	5.50e-07	1442	132	20	35575683
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	SART3 MAGI3 ZNFX1 MAGI2 MACF1 IFT80 PLXNB3	6.93e-07	130	132	7	12421765
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	SART3 HK1 AKAP8 SRSF6 MYCBP2 DYNC2H1 POLE TTC3 ELAC2 DHX9 SNW1 PNPLA6 DNAJA4 SYNE2 GMDS DLG1 MACF1 IFT80 EPB41L2 SOD1	8.86e-07	1487	132	20	33957083
Pubmed	Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.	SPTB ADGRB3 MAGI3 CDKL5 DLG1 MACF1 DLG3 AFDN	9.29e-07	197	132	8	36604605
Pubmed	TRIM50 regulates Beclin 1 proautophagic activity.	TRIM73 TRIM50 TRIM74	1.06e-06	6	132	3	29604308
Pubmed	TRIM50 promotes NLRP3 inflammasome activation by directly inducing NLRP3 oligomerization.	TRIM73 TRIM50 TRIM74	1.06e-06	6	132	3	36178239
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	GPHN SART3 KIAA0930 MYCBP2 DYNC2H1 RBBP7 AMBRA1 MAGI3 ATG2A TFAP4 PSMD6 POLR3B ADSL DLG1 CTSB UTRN	1.44e-06	1005	132	16	19615732
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	AKAP8 SRSF6 MYCBP2 TFAP4 RPRD1B DHX9 TRAFD1 PNPLA6 WDHD1 ACIN1 DLG1 AFDN EPB41L2 CYTH4	1.58e-06	774	132	14	15302935
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	GPHN SART3 SYN3 MYCBP2 ADGRB3 ZNFX1 RBM39 PSMD6 MAGI2 CDKL5 PPP3R1 DLG1 MACF1 DLG3 AFDN POLD3 EPB41L2	1.59e-06	1139	132	17	36417873
Pubmed	Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.	GPHN HK1 RBBP7 ACOT7 RBM39 DHX9 PSMD6 ADSL WDHD1 EHHADH ACIN1 AFDN RPL11	1.63e-06	665	132	13	30457570
Pubmed	Charting the landscape of tandem BRCT domain-mediated protein interactions.	HK1 SRSF4 AKAP8 SRSF6 DYNC2H1 RBBP7 WDR33 CFL1 RBM39 RPRD1B WDHD1 NCAPD2 RPL11	1.77e-06	670	132	13	22990118
Pubmed	Allele-specific binding of ZFP57 in the epigenetic regulation of imprinted and non-imprinted monoallelic expression.	TRIM73 TRIM50 TRIM74	1.85e-06	7	132	3	26025256
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	SART3 HK1 KIF27 SRSF6 DYNC2H1 CFL1 POLE TTC3 RBM39 RPRD1B DHX9 PSMD6 SNW1 ADSL NCAPD2 ACIN1 AFDN EPB41L2 RPL11	1.94e-06	1425	132	19	30948266
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	GPHN SPEG ZNFX1 NAV2 CHD6 IFT80 PREX1	2.07e-06	153	132	7	10718198
Pubmed	R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.	SART3 SRSF4 SRSF6 RBM39 DHX9 POLR3B SNW1 EHHADH RPL11	2.35e-06	300	132	9	28561026
Pubmed	TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.	SART3 SRSF4 AKAP8 SRSF6 RBBP7 WDR33 CFL1 CYTH1 DHX9 PSMD6 SNW1 CLK3 NCAPD2 ACIN1 SOD1	2.42e-06	922	132	15	27609421
Pubmed	Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.	SRSF4 SRSF6 MYCBP2 RBBP7 CFL1 RBM39 DHX9 PSMD6 SNW1 CLK3 NCAPD2 ACIN1 DLG1 RPL11	2.64e-06	809	132	14	32129710
Pubmed	The protein interaction landscape of the human CMGC kinase group.	SRSF4 AKAP8 SRSF6 WDR33 NEB RBM39 DHX9 CDKL5 TRAFD1 CLK3 ACIN1 CTSB ZNF281	2.65e-06	695	132	13	23602568
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	GPHN SART3 RBBP7 CFL1 ACOT7 RBM39 SNW1 ZNF724 ACIN1 MACF1 ZNF281 UTRN EPB41L2 RPL11 SOD1	2.83e-06	934	132	15	33916271
Pubmed	Proteomic analysis of beta1-adrenergic receptor interactions with PDZ scaffold proteins.	MAGI3 MAGI2 DLG1	2.95e-06	8	132	3	16316992
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	SART3 HK1 WDR33 CFL1 ADGRB3 RBM39 ELAC2 PSMD6 POLR3B NCAPD2 MACF1 UTRN EPB41L2 RPL11	4.47e-06	847	132	14	35235311
Pubmed	Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.	THOC7 SRSF4 SRSF6 RBBP7 WDR33 CFL1 RBM39 DHX9 SNW1 CLK3 ACIN1 RPL11 SOD1	4.58e-06	731	132	13	29298432
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	KIAA0930 MYCBP2 CFL1 POLE SPEG CYTH1 GRK5 AMBRA1 ATG2A TTC3 ELAC2 PNPLA6 NCAPD2 NAV2 PREX1 CYTH4	4.84e-06	1105	132	16	35748872
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	THOC7 SRSF4 SRSF6 WDR33 CFL1 ACOT7 RBM39 ELAC2 DHX9 SNW1 ADSL ACIN1 DLG1 POLD3 ZNF281 RPL11 SOD1	5.30e-06	1247	132	17	27684187
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	AKAP8 SRSF6 MYCBP2 CFL1 RBM39 DHX9 PSMD6 SNW1 SYNE2 ACIN1 MACF1 AFDN UTRN EPB41L2 RPL11	8.53e-06	1024	132	15	24711643
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	THOC7 SRSF4 AKAP8 SRSF6 RBBP7 WDR33 ZKSCAN8 TFAP4 RBM39 RPRD1B DHX9 SNW1 OSBPL3 ACIN1 CHD6 ZNF281 RPL11	8.60e-06	1294	132	17	30804502
Pubmed	DGKι regulates presynaptic release during mGluR-dependent LTD.	GPHN DLG1 DLG3	8.62e-06	11	132	3	21119615
Pubmed	USP11 mediates repair of DNA-protein cross-links by deubiquitinating SPRTN metalloprotease.	KIAA0930 CFL1 RBM39 ELAC2 DHX9 ADSL CLK3 GMDS POLD3 ZNF281 RPL11	1.11e-05	565	132	11	33567341
Pubmed	Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex.	GPHN SYNE2 DLG1 MACF1	1.19e-05	37	132	4	27565344
Pubmed	Lysine acetylation targets protein complexes and co-regulates major cellular functions.	KIAA0930 SRSF4 SRSF6 RNF213	1.32e-05	38	132	4	19608861
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	PSMD6 KSR1 ADSL WDHD1 CLK3 OSBPL3 CROCC2 ZNF724 POC5 TRIM50 MTO1 RPL11	1.33e-05	689	132	12	36543142
Pubmed	Familial amyotrophic lateral sclerosis (FALS)-linked SOD1 mutation accelerates neuronal cell death by activating cleavage of caspase-4 under ER stress in an in vitro model of FALS.	CASP4 SOD1	1.43e-05	2	132	2	20816908
Pubmed	Serine- and arginine-rich proteins 55 and 75 (SRp55 and SRp75) induce production of HIV-1 vpr mRNA by inhibiting the 5'-splice site of exon 3.	SRSF4 SRSF6	1.43e-05	2	132	2	20685659
Pubmed	GRK5 Controls SAP97-Dependent Cardiotoxic β1 Adrenergic Receptor-CaMKII Signaling in Heart Failure.	GRK5 DLG1	1.43e-05	2	132	2	32507058
Pubmed	Differential regulation of maternal and paternal chromosome condensation in mitotic zygotes.	AKAP8 NCAPD2	1.43e-05	2	132	2	12082153
Pubmed	A subset of SR proteins activates splicing of the cardiac troponin T alternative exon by direct interactions with an exonic enhancer.	SRSF4 SRSF6	1.43e-05	2	132	2	7651409
Pubmed	NABP1, a novel RORgamma-regulated gene encoding a single-stranded nucleic-acid-binding protein.	NABP1 NABP2	1.43e-05	2	132	2	16533169
Pubmed	GRK5-mediated exacerbation of pathological cardiac hypertrophy involves facilitation of nuclear NFAT activity.	GRK5 NFATC3	1.43e-05	2	132	2	25332207
Pubmed	Localization of Dlg at the mammalian neuromuscular junction.	DLG1 UTRN	1.43e-05	2	132	2	9674605
Pubmed	ABCB6 RNA expression in leukemias--expression is low in acute promyelocytic leukemia and FLT3-ITD-positive acute myeloid leukemia.	FLT3 ABCB6	1.43e-05	2	132	2	23793916
Pubmed	Cloning and characterization of E-dlg, a novel splice variant of mouse homologue of the Drosophila discs large tumor suppressor binds preferentially to SAP102.	DLG1 DLG3	1.43e-05	2	132	2	18618587
Pubmed	Role of SAP97 protein in the regulation of corticotropin-releasing factor receptor 1 endocytosis and extracellular signal-regulated kinase 1/2 signaling.	MAGI3 MAGI2 DLG1	1.49e-05	13	132	3	23576434
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	SRSF6 RBBP7 POLE ZKSCAN8 TFAP4 RBM39 DHX9 SNW1 NFATC3 ACIN1 EPB41L2	1.49e-05	583	132	11	29844126
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	SART3 AKAP8 RBBP7 CYTH1 ABCB6 PNPLA6 CLK3 NCAPD2 DLG1 MACF1 DLG3 AFDN CHD6 DHRS2 ZNF281 UTRN PREX1 EPB41L2	1.51e-05	1497	132	18	31527615
Pubmed	BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.	PDXDC1 SART3 MYLK CFL1 ZNFX1 DHX9 ADSL ACIN1 MACF1 AFDN CTSB UTRN	1.82e-05	711	132	12	33022573
Pubmed	RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.	THOC7 SRSF4 AKAP8 SRSF6 WDR33 ZKSCAN8 RBM39 ELAC2 DHX9 CLK3 ACIN1 RPL11	1.87e-05	713	132	12	29802200
Pubmed	Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes.	MYCBP2 RBM39 WDHD1 NFATC3 ACIN1	1.88e-05	85	132	5	16051665
Pubmed	Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.	SRSF4 AKAP8 SRSF6 RBBP7 CFL1 RBM39 DHX9 PSMD6 SNW1 EHHADH CLK3 RPL11	1.89e-05	714	132	12	28302793
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KIAA0930 DYNC2H1 RNF213 MAGI3 OSBPL3 MACF1 PREX1 REXO1L1P MEX3B SEC14L1	2.00e-05	493	132	10	15368895
Pubmed	Proteomic analysis of the SIRT6 interactome: novel links to genome maintenance and cellular stress signaling.	SART3 RBBP7 WDHD1 NCAPD2 POLD3	2.10e-05	87	132	5	24169447
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	SRSF4 AKAP8 SRSF6 RBBP7 CFL1 TFAP4 RBM39 DHX9 SNW1 PNPLA6 OSBPL3 ACIN1 RPL11	2.17e-05	847	132	13	35850772
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	GPHN SRSF6 RBBP7 WDR33 RPRD1B TRAFD1 SNW1 ACIN1 EPB41L2	2.31e-05	399	132	9	35987950
Pubmed	Brain-specific angiogenesis inhibitor-1 signaling, regulation, and enrichment in the postsynaptic density.	MAGI3 MAGI2 DLG1	2.35e-05	15	132	3	23782696
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	SART3 THOC7 AKAP8 SRSF6 CFL1 TUT7 RBM39 DHX9 SNW1 PNPLA6 CLK3 KCTD20 ACIN1 DLG1 EPB41L2 RPL11	2.37e-05	1257	132	16	36526897
Pubmed	Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression.	THOC7 MYLK AKAP8 SRSF6 TFAP4 RBM39 TRAFD1 LPL ACIN1	2.49e-05	403	132	9	35253629
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	MYCBP2 ADGRB3 SYNE2 NAV2 MACF1 CHD6 PREX1	2.57e-05	225	132	7	12168954
Pubmed	Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.	ANKRD31 FLT3 ZNFX1 NEB EHHADH MACF1	2.63e-05	152	132	6	34299191
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	PDXDC1 SART3 RBBP7 WDR33 SNW1 WDHD1 KCTD20 UTRN	2.76e-05	313	132	8	38270169
Pubmed	ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ.	SART3 MYCBP2 RBBP7 CFL1 AMBRA1 TTC3 DHX9 TRAFD1 SNW1 POLD3 RPL11	2.77e-05	624	132	11	33729478
Pubmed	The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome.	TRIM73 TRIM50 TRIM74	2.89e-05	16	132	3	22792322
Pubmed	Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry.	RBBP7 TUT7 DHX9 NCAPD2 DLG1 DLG3 UTRN EPB41L2 RPL11	2.91e-05	411	132	9	36652389
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	GPHN SYN3 CFL1 SPEG RBM39 MACF1 EPB41L2	3.04e-05	231	132	7	16452087
Pubmed	Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets.	FLT3 RBBP7 POLE NABP1 WDHD1 ACIN1	3.15e-05	157	132	6	30686591
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	SART3 RBBP7 POLE RNF213 TFAP4 ELAC2 RPRD1B DHX9 POLR3B SNW1 WDHD1 NCAPD2 ACIN1 POLD3	3.31e-05	1014	132	14	32416067
Pubmed	A Role for Mitochondrial Translation in Promotion of Viability in K-Ras Mutant Cells.	HGF CFL1 POLE RBM39 ELAC2 DHX9 SNW1 RPL11 SOD1	3.38e-05	419	132	9	28700943
Pubmed	Expanding the Interactome of TES by Exploiting TES Modules with Different Subcellular Localizations.	HK1 KIF27 AKAP8 CFL1 TRAFD1 MACF1 UTRN	3.39e-05	235	132	7	28378594
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	DYNC2H1 POLE ZNFX1 NEB RPRD1B WDHD1 SYNE2 CHD6 CTSB ZNF281 PREX1	3.39e-05	638	132	11	31182584
Pubmed	The Activation-Induced Assembly of an RNA/Protein Interactome Centered on the Splicing Factor U2AF2 Regulates Gene Expression in Human CD4 T Cells.	HK1 SRSF4 SRSF6 CFL1 DHX9 SNW1 ACIN1	3.77e-05	239	132	7	26641092
Pubmed	RioK1, a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln for binding and modulates PRMT5 complex composition and substrate specificity.	SART3 SRSF4 SRSF6 RBBP7 ZNFX1 RBM39 DHX9 POLR3B RPL11	3.77e-05	425	132	9	21081503
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	GPHN SART3 HK1 SRSF4 AKAP8 SRSF6 RBM39 DHX9 PSMD6 SNW1 WDHD1	4.18e-05	653	132	11	33742100
Pubmed	Hexokinase I N-terminal based peptide prevents the VDAC1-SOD1 G93A interaction and re-establishes ALS cell viability.	HK1 SOD1	4.28e-05	3	132	2	27721436
Pubmed	Calcineurin/Nfat signaling is required for perinatal lung maturation and function.	PPP3R1 NFATC3	4.28e-05	3	132	2	16998587
Pubmed	The ubiquitin ligase Phr1 regulates axon outgrowth through modulation of microtubule dynamics.	MYCBP2 MAP3K12	4.28e-05	3	132	2	18031680
Pubmed	HGF-induced migration depends on the PI(3,4,5)P3-binding microexon-spliced variant of the Arf6 exchange factor cytohesin-1.	HGF CYTH1	4.28e-05	3	132	2	30404949
Pubmed	Compartmentalized NRG signaling and PDZ domain-containing proteins in synapse structure and function.	DLG1 DLG3	4.28e-05	3	132	2	12175853
Interaction	IQSEC3 interactions	GPHN MYCBP2 MAGI2 UTRN	1.67e-06	14	132	4	int:IQSEC3
Interaction	YWHAG interactions	GPHN HGF KIAA0930 AKAP8 MYCBP2 CFL1 SPEG CYTH1 GRK5 MAGI3 RGS12 KSR1 NFATC3 CLK3 OSBPL3 SYNE2 NAV2 ACIN1 MACF1 AFDN UTRN MEX3B EPB41L2 SOD1	1.73e-06	1248	132	24	int:YWHAG
Interaction	YWHAQ interactions	KIAA0930 SRSF6 MYCBP2 CFL1 SPEG GRK5 SPTB NEB MAP3K12 RBM39 RGS12 DHX9 KSR1 WDHD1 NFATC3 CLK3 OSBPL3 NAV2 MACF1 AFDN EPB41L2 SOD1	3.45e-06	1118	132	22	int:YWHAQ
Interaction	DLGAP2 interactions	GRK5 MAGI2 CDKL5 DLG1 DLG3	5.38e-06	39	132	5	int:DLGAP2
Interaction	CLK2 interactions	SRSF4 SRSF6 WDR33 RBM39 EHHADH CLK3 ACIN1 TRIM50 EPB41L2	5.63e-06	195	132	9	int:CLK2
Interaction	CEBPB interactions	THOC7 HK1 SRSF4 AKAP8 SRSF6 RBBP7 WDR33 CFL1 ACOT7 CASP4 TFAP4 RBM39 RPRD1B DHX9 PSMD6 KSR1 WDHD1 DNAJA4 ACIN1 POLD3 CTSB ZNF281 RPL11 SOD1	2.02e-05	1443	132	24	int:CEBPB
Interaction	PRNP interactions	GPHN MYLK ZKSCAN8 PSMD6 MAGI2 KSR1 ADSL WDHD1 CLK3 OSBPL3 CROCC2 ZNF724 DLG1 MACF1 DLG3 AFDN POC5 TRIM50 MTO1 EPB41L2 RPL11	2.04e-05	1158	132	21	int:PRNP
Interaction	PPIG interactions	SART3 SRSF4 SRSF6 GRK5 RBM39 CLK3 EPB41L2	2.05e-05	127	132	7	int:PPIG
Interaction	SIRT7 interactions	SART3 HK1 SRSF4 MYCBP2 RBBP7 POLE TUT7 RBM39 SNW1 SYNE2 NCAPD2 ACIN1 MACF1 AFDN UTRN EPB41L2	2.96e-05	744	132	16	int:SIRT7
Interaction	KCTD13 interactions	GPHN SART3 HK1 SYN3 RBBP7 CFL1 SPTB ACOT7 ZNFX1 RBM39 DHX9 PSMD6 MAGI2 CDKL5 PNPLA6 DLG1 MACF1 DLG3 AFDN UTRN EPB41L2 RPL11 SOD1	3.50e-05	1394	132	23	int:KCTD13
Interaction	HUWE1 interactions	GPHN FLT3 SRSF4 SRSF6 MYCBP2 RBBP7 SPTB AMBRA1 TTC3 RPRD1B PSMD6 TRAFD1 SNW1 ADSL NCAPD2 GMDS DLG1 MACF1 CTSB SOD1	3.60e-05	1110	132	20	int:HUWE1
Interaction	CUL4A interactions	HK1 KIF27 RBBP7 GRK5 AMBRA1 RNF213 NLRP1 RBM39 C4orf54 RGS12 DHX9 ADSL WDHD1 NAV2 AFDN CTSB RPL11	4.34e-05	854	132	17	int:CUL4A
Interaction	CLEC16A interactions	PDXDC1 AKAP8 MYCBP2 DYNC2H1 POLE RANBP6 AMBRA1 PSMD6 TRAFD1 PNPLA6 NCAPD2 POLD3 MTO1 CTSB	6.67e-05	629	132	14	int:CLEC16A
Interaction	HDAC11 interactions	AKAP8 MYCBP2 WDR33 SNW1 OSBPL3 SYNE2 ACIN1	7.04e-05	154	132	7	int:HDAC11
Interaction	ZNF724 interactions	ZKSCAN8 ZNF724 DHRS2 RPL11	8.80e-05	36	132	4	int:ZNF724
Interaction	GOT2 interactions	THOC7 MYLK CFL1 ACOT7 RBM39 ABCD2 UTRN	9.31e-05	161	132	7	int:GOT2
Interaction	PPP1CC interactions	SRSF4 SRSF6 MYCBP2 RBBP7 RPRD1B CDKL5 POLR3B SNW1 OSBPL3 KCTD20 ACIN1 DLG1 DLG3 EPB41L2 RPL11	1.00e-04	738	132	15	int:PPP1CC
Interaction	YWHAB interactions	KIAA0930 AKAP8 MYCBP2 SPEG GRK5 NEB RGS12 DHX9 KSR1 NFATC3 CLK3 OSBPL3 NAV2 MACF1 AFDN MEX3B EPB41L2 SOD1	1.11e-04	1014	132	18	int:YWHAB
Interaction	SRSF7 interactions	SRSF4 SRSF6 RBBP7 WDR33 RBM39 DHX9 SNW1 CLK3 ACIN1 MALSU1 RPL11	1.14e-04	425	132	11	int:SRSF7
Interaction	YWHAZ interactions	KIAA0930 AKAP8 MYCBP2 CFL1 SPEG GRK5 NEB RBM39 RGS12 KSR1 ADSL NFATC3 CLK3 OSBPL3 SYNE2 NAV2 MACF1 AFDN MEX3B EPB41L2 SOD1	1.32e-04	1319	132	21	int:YWHAZ
Interaction	C9orf72 interactions	PDXDC1 HK1 AKAP8 SRSF6 SYN3 MYCBP2 RBBP7 TRIM73 CFL1 POLE AMBRA1 RBM39 ELAC2 DHX9 PSMD6 TRAFD1 SNW1 ADSL GMDS POLD3 RPL11	1.32e-04	1319	132	21	int:C9orf72
Interaction	MEN1 interactions	SART3 SRSF4 AKAP8 SRSF6 RBBP7 WDR33 RNF213 TFAP4 DHX9 SNW1 PNPLA6 WDHD1 OSBPL3 NCAPD2 ACIN1 AFDN ZNF281 RPL11	1.33e-04	1029	132	18	int:MEN1
Interaction	CAVIN1 interactions	HK1 AKAP8 TMEM63B MAGI3 DHX9 ACIN1 UTRN EPB41L2 RPL11	1.33e-04	292	132	9	int:CAVIN1
Interaction	SNRPB interactions	SART3 THOC7 SRSF4 AKAP8 RBM39 RPRD1B DHX9 MAGI2 SNW1 NCAPD2 ACIN1 MACF1	1.54e-04	517	132	12	int:SNRPB
Interaction	KCNJ2 interactions	HK1 NCAPD2 DLG1 DLG3	1.62e-04	42	132	4	int:KCNJ2
Interaction	THRAP3 interactions	SART3 SRSF4 AKAP8 SRSF6 MYCBP2 RBBP7 RBM39 DHX9 CLK3 ACIN1 RPL11	1.63e-04	443	132	11	int:THRAP3
Interaction	SSRP1 interactions	THOC7 AKAP8 SRSF6 POLE RBM39 RPRD1B DHX9 PSMD6 SNW1 WDHD1 NABP2 ACIN1 POLD3 RPL11	1.63e-04	685	132	14	int:SSRP1
Interaction	ACIN1 interactions	SRSF4 SRSF6 GRK5 RBM39 DHX9 SNW1 CLK3 ACIN1 EPB41L2	1.67e-04	301	132	9	int:ACIN1
Interaction	ACTA1 interactions	MYLK CFL1 CYTH1 DUSP19 DHX9 SNW1 DLG1 MACF1 UTRN EPB41L2	1.69e-04	371	132	10	int:ACTA1
Interaction	DLGAP3 interactions	MAGI2 CDKL5 DLG1 DLG3	1.95e-04	44	132	4	int:DLGAP3
Interaction	PLXNB3 interactions	MAGI3 MAGI2 PLXNB3	2.09e-04	18	132	3	int:PLXNB3
Interaction	UBE2O interactions	AKAP8 SRSF6 DYNC2H1 RBBP7 CFL1 GRK5 ZKSCAN8 RBM39 PSMD6 CLK3 ACIN1 MACF1 DHRS2 EPB41L2 RPL11	2.11e-04	790	132	15	int:UBE2O
Interaction	HAGH interactions	FLT3 HK1 DHX9 CTSB SOD1	2.28e-04	84	132	5	int:HAGH
Interaction	RHBDL1 interactions	MAGI3 MAGI2 DLG3	2.46e-04	19	132	3	int:RHBDL1
Interaction	USP15 interactions	SART3 MYCBP2 RBBP7 GRK5 RNF213 TFAP4 PSMD6 MAGI2 ADSL OSBPL3 NCAPD2 TRIM74	2.54e-04	546	132	12	int:USP15
GeneFamily	PDZ domain containing	MAGI3 RGS12 MAGI2 DLG1 DLG3 AFDN SDCBP2 PREX1	1.15e-06	152	93	8	1220
GeneFamily	Calcium voltage-gated channel subunits\|Membrane associated guanylate kinases	MAGI3 MAGI2 DLG1 DLG3	8.99e-06	26	93	4	904
GeneFamily	Ring finger proteins	TRIM73 RNF213 TTC3 CHFR TRIM50 MEX3B TRIM74	5.42e-04	275	93	7	58
GeneFamily	RNA binding motif containing\|Serine and arginine rich splicing factors	SRSF4 SRSF6	1.67e-03	12	93	2	737
Coexpression	GSE25146_UNSTIM_VS_HELIOBACTER_PYLORI_LPS_STIM_AGS_CELL_UP	SRSF6 GRK5 CASP4 MAGI3 WDHD1 NCAPD2 ACIN1 MTO1	3.99e-06	180	133	8	M8127
Coexpression	LINDGREN_BLADDER_CANCER_CLUSTER_1_DN	PDXDC1 MYLK POLE GRK5 ACOT7 WDHD1 NAV2 B4GALNT3 PREX1 CDCA4	2.42e-05	378	133	10	M17788
Coexpression	TABULA_MURIS_SENIS_BRAIN_NON_MYELOID_NEURON_AGEING	KIAA0930 MYLK AKAP8 MYCBP2 CYTH1 ADGRB3 MSRA MAGI2 AKR1E2 PNPLA6 NABP2 KCTD20 IFT80 MALSU1 SDCBP2 SEC14L1	2.79e-05	954	133	16	MM3689
Coexpression	GSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_2H_UP	POLE CASP4 RNF213 NEB TRAFD1 WDHD1 NCAPD2	4.28e-05	183	133	7	M2993
Coexpression	MORI_SMALL_PRE_BII_LYMPHOCYTE_DN	GPHN RBBP7 WDHD1 NFATC3 CDCA4	4.32e-05	76	133	5	M13396
Coexpression	MORI_SMALL_PRE_BII_LYMPHOCYTE_DN	GPHN RBBP7 WDHD1 NFATC3 CDCA4	4.89e-05	78	133	5	MM593
Coexpression	THAKAR_PBMC_INACTIVATED_INFLUENZA_AGE_21_30YO_RESPONDERS_28DY_DN	PDXDC1 KIAA0930 SRSF4 CFL1 CYTH1 NLRP1 ATG2A PNPLA6 CLK3 CHFR GMDS CTSB UTRN CYTH4 SEC14L1	5.77e-05	905	133	15	M40865
Coexpression	GSE16450_CTRL_VS_IFNA_12H_STIM_IMMATURE_NEURON_CELL_LINE_UP	GPHN MSRA POLR3B ATF7IP2 GMDS DLG1 UTRN	6.82e-05	197	133	7	M7403
Coexpression	GSE26156_DOUBLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_UP	SRSF6 CYTH1 CASP4 NLRP1 RBM39 SYNE2 RPL11	7.26e-05	199	133	7	M8298
Coexpression	GSE2405_HEAT_KILLED_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_24H_UP	CASP4 CHML CTCFL BARHL2 ATF7IP2 DLG1 EPB41L2	7.26e-05	199	133	7	M6218
Coexpression	GSE28726_ACT_CD4_TCELL_VS_ACT_VA24NEG_NKTCELL_DN	AKAP8 SRSF6 CYTH1 CASP4 RBM39 TOB1 SYNE2	7.49e-05	200	133	7	M8306
Coexpression	GSE24574_BCL6_HIGH_TFH_VS_TFH_CD4_TCELL_DN	AKAP8 SRSF6 CYTH1 CASP4 RBM39 TOB1 SYNE2	7.49e-05	200	133	7	M8331
Coexpression	GSE17721_CTRL_VS_CPG_2H_BMDC_UP	SART3 AKAP8 WDR33 PNPLA6 DLG1 POC5 ABCD2	7.49e-05	200	133	7	M3759
Coexpression	GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_2H_DN	FLT3 POLE CHML AKR1E2 ATF7IP2 KCTD20 IFT80	7.49e-05	200	133	7	M6037
Coexpression	GSE25088_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_DN	MYCBP2 CFL1 POLE WDHD1 NFATC3 OSBPL3 AFDN	7.49e-05	200	133	7	M7983
Coexpression	KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP	WDR33 ATG2A NABP1 RBM39 KSR1 TRAFD1 LPL CHFR GMDS CHD6 POC5 IFT80 UTRN PREX1 SEC14L1	9.02e-05	942	133	15	M8144
Coexpression	ZHENG_CORD_BLOOD_C10_MULTILYMPHOID_PROGENITOR	CYTH1 TTC3 OSBPL3 PREX1 CYTH4	1.38e-04	97	133	5	M39219
Coexpression	HOEBEKE_LYMPHOID_STEM_CELL_UP	NLRP1 RBM39 OSBPL3 MACF1 CYTH4	1.38e-04	97	133	5	M14698
ToppCell	ILEUM-inflamed-(3)_MNP-(3)_moDC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	MRC1 SRSF6 ATG2A CHML RBM39 DLG1 UTRN EPB41L2 SEC14L1	5.33e-09	187	133	9	0099def970fbc828756fbf853eca2ce77b8cd342
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-conventional_dendritic_cell\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MRC1 HK1 ACOT7 CHML LPL CTSB RPL11 SOD1	1.00e-07	188	133	8	e35104ca327c2d9eb6ffed658051f62f855a0a0e
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4\|GI_small-bowel / Manually curated celltypes from each tissue	CYTH1 RNF213 MAGI3 NABP1 SYNE2 ATF7IP2 AFDN CTSB	1.28e-07	194	133	8	4547b57669be5d4f0de55175802ee04372288a6a
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	TMEM63B MAGI3 CDKL5 OSBPL3 SYNE2 NAV2 IFT80 UTRN	1.55e-07	199	133	8	d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	TMEM63B MAGI3 CDKL5 OSBPL3 SYNE2 NAV2 IFT80 UTRN	1.61e-07	200	133	8	8683445ad5b70748c4a1f12eb77d47623085147e
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	MYCBP2 CYTH1 RNF213 RBM39 SYNE2 ACIN1 MACF1 UTRN	1.61e-07	200	133	8	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	wk_20-22-Hematologic-Meg-ery-Definitive_erythroblast\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ESPN GALNTL6 SPTB TMEM63B ABCB6 ATG2A UBAC1	1.28e-06	182	133	7	0c77ef4556c1d1512ebe9077df858b28f9e38dd5
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MRC1 HK1 ACOT7 LPL CTSB RPL11 SOD1	1.76e-06	191	133	7	5c0c44612b4cdbf89c0f1f219416374a7541f610
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MYLK SYN3 GRK5 ADGRB3 MAGI2 NAV2 MACF1	1.89e-06	193	133	7	99525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell	LPS_IL1RA_TNF\|World / Treatment groups by lineage, cell group, cell type	HGF MYLK DYNC2H1 ADGRB3 TOB1 LPL UTRN	2.17e-06	197	133	7	0a6550dce156fc81f15b1e7830d331ca50d87d06
ToppCell	Control-Control-Lymphocyte-T/NK-NK_activated\|Control / Disease, condition lineage and cell class	POLE RNF213 MAGI2 SYNE2 MACF1 DLG3 UTRN	2.24e-06	198	133	7	76d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MAGI3 CDKL5 OSBPL3 SYNE2 NAV2 IFT80 UTRN	2.32e-06	199	133	7	a270630626df614f8605abddb7dee7c4d74f6149
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	GPHN ADGRB3 AMBRA1 MAGI3 MAGI2 DLG1 UTRN	2.32e-06	199	133	7	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / Treatment groups by lineage, cell group, cell type	TMEM63B MAGI3 OSBPL3 SYNE2 NAV2 AFDN UTRN	2.39e-06	200	133	7	2dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCell	3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	RNF213 ATG2A RBM39 SYNE2 MACF1 UTRN	3.27e-06	135	133	6	ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCell	metastatic_Lymph_Node-Myeloid_cells-Alveolar_Mac\|Myeloid_cells / Location, Cell class and cell subclass	MRC1 ADGRB3 ACOT7 CCDC168 PNPLA6 LPL	4.21e-06	141	133	6	399380de5ea09e22fd128e3e55fffeffc4874c15
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	PDXDC1 RNF213 NABP1 RBM39 SYNE2 MACF1	7.53e-06	156	133	6	1545169694f686d28648a68b552c2ae606599d66
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	RNF213 NABP1 RBM39 SYNE2 MACF1 UTRN	1.27e-05	171	133	6	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MRC1 NABP1 LPL ABCD2 CTSB PREX1	1.31e-05	172	133	6	584af6537685cb459bf0fc298e6f46872016c116
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MRC1 NABP1 LPL ABCD2 CTSB CYTH4	1.36e-05	173	133	6	7713716ec95932b2fac177ce4cfec027b4754cef
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MRC1 HAO1 NABP1 WDHD1 LPL CTSB	1.50e-05	176	133	6	270d7908dbd84028958d257f94941dc685e20255
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PDXDC1 KSR1 DNAJA4 DLG1 MACF1 B4GALNT3	1.65e-05	179	133	6	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	RNF213 NABP1 OSBPL3 SYNE2 MACF1 TRIM74	1.75e-05	181	133	6	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GRK5 MAGI3 ATF7IP2 NAV2 AFDN UTRN	1.92e-05	184	133	6	57c792e6e2fedba25d3350ffe649fd74750b579d
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MRC1 NABP1 LPL ABCD2 CTSB CYTH4	1.92e-05	184	133	6	fe9ea4d0e0be820e95eaf9bb42a5560d0e177574
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4\|TCGA-Pancreas / Sample_Type by Project: Shred V9	HGF MYCBP2 NFATC3 KCTD20 UTRN EPB41L2	1.92e-05	184	133	6	67164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GRK5 MAGI3 ATF7IP2 NAV2 AFDN UTRN	1.92e-05	184	133	6	d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	MYCBP2 TRIM73 RNF213 OSBPL3 MACF1 IFT80	1.98e-05	185	133	6	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MRC1 CHML LPL CTSB RPL11 SOD1	2.04e-05	186	133	6	38f9f7d3b782978fd23b2a7fe565266285d39e44
ToppCell	Myeloid-B_(Activated_Macrophage)\|World / shred on cell class and cell subclass (v4)	MRC1 NABP1 LPL ABCD2 CTSB CYTH4	2.04e-05	186	133	6	33d731a7883d75e4e7db83b641cdb1e9a39938bf
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	MYCBP2 TRIM73 RNF213 OSBPL3 MACF1 IFT80	2.04e-05	186	133	6	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MRC1 NABP1 LPL ABCD2 CTSB CYTH4	2.04e-05	186	133	6	7950e03ea080238c168b9d807e217f459acdfb28
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	HGF MYLK GRK5 ADGRB3 MAGI2 EPB41L2	2.11e-05	187	133	6	a9316e2818217ec5feae9cf8816f7249803caee6
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	RNF213 NABP1 RBM39 SYNE2 MACF1 UTRN	2.17e-05	188	133	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYLK MYCBP2 MACF1 AFDN UTRN EPB41L2	2.30e-05	190	133	6	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	pdx-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	POLE WDHD1 ZNF43 NCAPD2 POLD3 CDCA4	2.30e-05	190	133	6	d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCell	Myeloid-Myeloid-B_(Activated_Macrophage)\|Myeloid / shred on cell class and cell subclass (v4)	MRC1 NABP1 LPL ABCD2 CTSB EPB41L2	2.37e-05	191	133	6	7bf125249af1e8bb138ed4d999fdd74b03ab2447
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	MAGI3 RBM39 DLG1 AFDN CHD6 UTRN	2.44e-05	192	133	6	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	RNF213 NLRP1 NABP1 RBM39 SYNE2 MACF1	2.44e-05	192	133	6	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	Children_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MRC1 CFL1 PNPLA6 LPL CTSB RPL11	2.52e-05	193	133	6	8b2f89c3cf137315eed05d9edb5fc6011c5325a8
ToppCell	human_hepatoblastoma-Tumor_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	MAGI3 NFATC3 ATF7IP2 DLG1 AFDN CHD6	2.52e-05	193	133	6	503a979328c68b096680b71359a26f02fafdff35
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	MAGI3 RBM39 DLG1 AFDN CHD6 UTRN	2.52e-05	193	133	6	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MYLK SYN3 GRK5 ADGRB3 MAGI2 NAV2	2.59e-05	194	133	6	e93de9428c986b8943fc169258847c650cfab0e5
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	HGF MYLK ADGRB3 MAGI2 LPL RPL11	2.59e-05	194	133	6	a3e5a15cf6c1361207f661ee15eb634f77daf1cb
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	GPHN AMBRA1 MAGI3 MAGI2 NAV2 DLG1	2.74e-05	196	133	6	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	10x5'v1-week_12-13-Hematopoietic-erythroid\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ESPN SPTB TMEM63B DNAJA4 UBAC1 SOD1	2.74e-05	196	133	6	0aae78e73d53416d857bdf21f595a0a0a0ba7944
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ACOT7 WDHD1 NABP2 NCAPD2 POLD3 CDCA4	2.74e-05	196	133	6	de70cc301a8cbaedb0a5ea4a6442dcdaa477822d
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CFL1 CASP4 RNF213 ATG2A RBM39 SYNE2	2.74e-05	196	133	6	17f17edadafdad9f24e88d708d7e1c765503131c
ToppCell	COVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MRC1 CYTH1 RNF213 CTSB PREX1 CYTH4	2.82e-05	197	133	6	e42910a653a1b5bd90c090e9665a84871ed2873f
ToppCell	LPS_IL1RA_TNF-Hematopoietic_Myeloid-Dendritic_cells-pDC\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FLT3 NLRP1 DNAJA4 ABCD2 CTSB CYTH4	2.82e-05	197	133	6	8fa38fb95e285f9cc756ec4f32009be4ede09d3c
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TRIM73 RNF213 RBM39 SYNE2 MACF1 UTRN	2.82e-05	197	133	6	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.0.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MRC1 CFL1 ACOT7 PNPLA6 LPL CTSB	2.82e-05	197	133	6	bf0f64bd356584cd4f8ac68867604c2118067450
ToppCell	COVID-19_Severe-PLT_0\|COVID-19_Severe / Disease Group and Platelet Clusters	HK1 CFL1 SPTB KCTD20 MACF1 SOD1	2.82e-05	197	133	6	dbdeefa72d10f2c5f75ad5aac6f31a892d4e94a9
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	MYLK GRK5 ADGRB3 LPL MACF1 AFDN	2.82e-05	197	133	6	0034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCell	COVID-19-lung-Macrophage_VCANhi_FCN1hi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CYTH1 RNF213 PNPLA6 CTSB PREX1 CYTH4	2.90e-05	198	133	6	ea34096bee852a7e996f097fa279381afa8f86ff
ToppCell	Immune\|World / Lineage, Cell type, age group and donor	MRC1 CYTH1 NLRP1 CTSB PREX1 CYTH4	2.90e-05	198	133	6	65681b54d13c6997bd90a1c2a12314a80e964fe3
ToppCell	Control_saline-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control_saline / Treatment groups by lineage, cell group, cell type	TMEM63B MAGI3 SYNE2 NAV2 IFT80 UTRN	2.90e-05	198	133	6	85f424cd9bb3117c9e322031024aabb87696ce47
ToppCell	Fetal_29-31_weeks-Immune\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MRC1 CYTH1 NLRP1 CTSB PREX1 CYTH4	2.90e-05	198	133	6	5dff131356b8c22743bd27b2b21f86ee6e4a0a0d
ToppCell	Adult-Immune\|Adult / Lineage, Cell type, age group and donor	MRC1 CYTH1 PNPLA6 CTSB PREX1 CYTH4	2.90e-05	198	133	6	9bfd7b88aa646eaf5eddb15cf985c7ca910cb35e
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	GPHN AMBRA1 MAGI3 MAGI2 NAV2 DLG1	2.90e-05	198	133	6	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TRIM73 RNF213 RBM39 SYNE2 MACF1 UTRN	2.99e-05	199	133	6	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	TMEM63B MAGI3 SYNE2 NAV2 IFT80 UTRN	2.99e-05	199	133	6	1c70e7d6bd25980e1b92aa1cac3f3c95d9651b4b
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	HGF MYLK MYCBP2 DYNC2H1 LPL MACF1	2.99e-05	199	133	6	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MRC1 RNF213 NABP1 UTRN PREX1 CYTH4	2.99e-05	199	133	6	5ceeed92f831d068ff4bb3994f420002338330e7
ToppCell	10x5'v1-week_14-16-Hematopoietic-erythroid-mid_erythroid\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	HK1 SPTB TMEM63B UBAC1 CTSB SOD1	2.99e-05	199	133	6	e6853b2c0ef6549d5554754c5d5f65825b66025b
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MRC1 NABP1 CHML PNPLA6 DNAJA4 LPL	2.99e-05	199	133	6	fde8e3ba19d19069a4d3b8db55bfe6220cf634d5
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	HGF MYLK DYNC2H1 LPL MACF1 EPB41L2	2.99e-05	199	133	6	30d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-T/NK-CD8+_T_naive\|COVID-19_Severe / Disease, condition lineage and cell class	TRIM73 TTC3 TOB1 ATF7IP2 RPL11 SOD1	2.99e-05	199	133	6	4fffd7b7355f8c56892e8e2d75f55f77b4e1bcc6
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	HGF MYLK DYNC2H1 LPL MACF1 EPB41L2	3.07e-05	200	133	6	9b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	RNF213 SYNE2 MACF1 AFDN UTRN SEC14L1	3.07e-05	200	133	6	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	mild-CD8+_Tem\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RNF213 ATG2A RBM39 SYNE2 MACF1 UTRN	3.07e-05	200	133	6	d8aec4904c9420b8f9d7508658ba1e36c66cdfcc
ToppCell	COVID-19-COVID-19_Severe-Others-RBC\|COVID-19_Severe / Disease, condition lineage and cell class	ESPN HK1 SPTB TMEM63B DNAJA4 CTSB	3.07e-05	200	133	6	308f74e7e13ecc6d133c219c42cc8895a96644c8
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	TMEM63B MAGI3 SYNE2 NAV2 IFT80 UTRN	3.07e-05	200	133	6	ddfb1f006365bf16203ee49f20200f68220cc288
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD14\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MRC1 FLT3 KSR1 CTSB PREX1 CYTH4	3.07e-05	200	133	6	5432bdf495431cd26f6e4cd585100f3652588913
ToppCell	mild-gd_T\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RNF213 ATG2A RBM39 SYNE2 MACF1 UTRN	3.07e-05	200	133	6	109f673a4967ffa52270a0b4f818b3461288db44
ToppCell	healthy_donor\|World / Disease condition, Lineage, Cell class and subclass	CYTH1 NLRP1 RBM39 SYNE2 MACF1 UTRN	3.07e-05	200	133	6	afd4d5609adaa470e3d880f8be4a4d55e162b3d6
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	HGF MYLK MYCBP2 DYNC2H1 LPL MACF1	3.07e-05	200	133	6	a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	MYCBP2 RNF213 RBM39 SYNE2 MACF1 UTRN	3.07e-05	200	133	6	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	metastatic_Brain-Fibroblasts-Smooth_muscle_cells\|Fibroblasts / Location, Cell class and cell subclass	KIF27 SPEG ZNF180 TFAP4 POC5	9.94e-05	154	133	5	423f58fc7dcef068458cbf7b4ee989e37227041e
ToppCell	metastatic_Lymph_Node-Myeloid_cells-Alveolar_Mac\|metastatic_Lymph_Node / Location, Cell class and cell subclass	MRC1 ADGRB3 PNPLA6 LPL CTSB	1.03e-04	155	133	5	03fd443740272dcb547e39deaf7ae89b8307f241
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GALNTL6 NLRP1 BTN2A2 PREX1 PLXNB3	1.16e-04	159	133	5	d3f81ba22160568ccaa6d2b04ebfd30630f9a6db
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ESPN RBBP7 DHX9 TOB1 SYNE2	1.26e-04	162	133	5	80317c4253bf8e897782e562f29835f181c65b98
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	SPEG SYNE2 MACF1 ABCD2 UTRN	1.26e-04	162	133	5	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	E18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYCBP2 NABP1 LPL NCAPD2 ABCD2	1.37e-04	165	133	5	1dcd6b8aa192baeaa1f7bb334843edab6049b96f
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MRC1 CHML NCAPD2 CTSB CYTH4	1.41e-04	166	133	5	bb8135119dc37fdbba476599a56d368f422688dc
ToppCell	facs-MAT-Fat-18m-Myeloid-macrophage\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 KIAA0930 FLT3 PREX1 CYTH4	1.45e-04	167	133	5	c2952d8ba763374c5678b92825c8956fc3e3ecd2
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FAM228A NEB MACF1 POLD3 ABCD2	1.54e-04	169	133	5	16c52a0f6d96ecc1832922fce9b39691849f0d73
ToppCell	E16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MRC1 NABP1 LPL ATF7IP2 ABCD2	1.54e-04	169	133	5	305cedbd97059029d7d2a248a8a4b6cfe281aa54
ToppCell	facs-Large_Intestine-Proximal-18m-Epithelial-enterocyte_of_epithelium_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ESPN MYLK CFL1 SDCBP2 SOD1	1.58e-04	170	133	5	75b0486620cab838d3feb1c3aa965b487a906618
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PDXDC1 RANBP6 AMBRA1 TOB1 AFDN	1.58e-04	170	133	5	adb625124832b0786a590e8f75b61e7263a1e0d4
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEB OSBPL3 IFT80 B4GALNT3 SDCBP2	1.62e-04	171	133	5	8719a18c9e6b6f5d8ec4e937c2bda1e36441c9ec
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-BM_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEB OSBPL3 IFT80 B4GALNT3 SDCBP2	1.62e-04	171	133	5	f4cdd7862c8fe99ee765a2f3ed375b584f4976c5
ToppCell	facs-Spleen-nan-24m-Lymphocytic-Cd3e_T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNTL6 NAV2 CTSB SDCBP2 UTRN	1.71e-04	173	133	5	f2eeff86e7dc7f4e3c36f775777d56685d7096cf
ToppCell	E18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYCBP2 NABP1 LPL ABCD2 CTSB	1.71e-04	173	133	5	279efbab7810fa60ab12ea5d09a84800df4adef0
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MRC1 NLRP1 LPL NCAPD2 ABCD2	1.76e-04	174	133	5	65147b0f8c2ccadd5685430d31081520c157536a
ToppCell	Control-Epithelial_cells-AT1\|Control / group, cell type (main and fine annotations)	GRK5 MAGI3 ATF7IP2 NAV2 AFDN	1.76e-04	174	133	5	548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCell	facs-Large_Intestine-Proximal-18m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ESPN MYLK CFL1 RPL11 SOD1	1.86e-04	176	133	5	d1c4c78a6d4a4ad37912eade4b7d16ef84b9a706
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MRC1 NABP1 LPL ABCD2 CTSB	1.86e-04	176	133	5	b0b87eebcf5c994386b39ca607e17f10e9d9de74
ToppCell	facs-Large_Intestine-Proximal-18m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ESPN MYLK CFL1 RPL11 SOD1	1.86e-04	176	133	5	8c2f830124b3bd7c3a483aabe060a1d202c4a409
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MRC1 NABP1 LPL ATF7IP2 CTSB	1.91e-04	177	133	5	67cc3a6461db5e0678f96b18224aeb83ad34b0f4
Drug	Sulfaguanidine [57-67-0]; Down 200; 18.6uM; HL60; HG-U133A	HGF AKAP8 TFAP4 WDHD1 NABP2 ACIN1 DLG1 MACF1 PRRG4 EPB41L2	2.08e-07	196	131	10	1995_DN
Drug	S(-)Eticlopride hydrochloride [97612-24-3]; Down 200; 10.6uM; MCF7; HT_HG-U133A	HGF SPEG CYTH1 GRK5 AMBRA1 BTN2A2 PPP3R1 DNAJA4 PRRG4	1.98e-06	195	131	9	3393_DN
Drug	Meclofenoxate hydrochloride [3685-84-5]; Down 200; 13.6uM; HL60; HT_HG-U133A	GPHN HGF AMBRA1 DHX9 BTN2A2 WDHD1 PRRG4 CTSB SEC14L1	2.34e-06	199	131	9	2546_DN
Drug	AC1L9LT0	GRK5 MAGI3 DLG1 DLG3 SDCBP2 UTRN SEC14L1	7.25e-06	123	131	7	CID000448294
Disease	asphyxiating thoracic dystrophy 3 (implicated_via_orthology)	DYNC2H1 IFT80	1.93e-05	2	130	2	DOID:0110087 (implicated_via_orthology)
Disease	autosomal recessive nonsyndromic deafness 36 (implicated_via_orthology)	ESPN ESPNL	1.93e-05	2	130	2	DOID:0110494 (implicated_via_orthology)
Disease	very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	PDXDC1 ANKRD31 RGS12 MSRA LPL SYNE2 MACF1	5.99e-05	222	130	7	EFO_0008317, EFO_0020943
Disease	colorectal cancer	HK1 ADGRB3 RANBP6 HAO1 NABP1 MAGI2 OSBPL3 UBAC1 MACF1 POLD3 PREX1	7.80e-05	604	130	11	MONDO_0005575
Disease	Motor Neuron Disease, Upper	PNPLA6 SOD1	1.15e-04	4	130	2	C0521659
Disease	Motor Neuron Disease, Secondary	PNPLA6 SOD1	1.15e-04	4	130	2	C0543858
Disease	Motor Neuron Disease	PNPLA6 SOD1	1.15e-04	4	130	2	C0085084
Disease	Familial Motor Neuron Disease	PNPLA6 SOD1	1.15e-04	4	130	2	C0270763
Disease	Motor Neuron Disease, Lower	PNPLA6 SOD1	1.15e-04	4	130	2	C0270764
Disease	Jeune thoracic dystrophy	DYNC2H1 IFT80	1.15e-04	4	130	2	cv:C0265275
Disease	Anterior Horn Cell Disease	PNPLA6 SOD1	1.15e-04	4	130	2	C0154681
Disease	free cholesterol to total lipids in medium VLDL percentage	PDXDC1 ANKRD31 RGS12 LPL	1.19e-04	57	130	4	EFO_0022284
Disease	body surface area	PDXDC1 SYN3 CYTH1 TFAP4 ADSL GMDS MACF1 POC5 B4GALNT3 POLD3 EPB41L2	1.35e-04	643	130	11	EFO_0022196
Disease	free cholesterol to total lipids in very large VLDL percentage	PDXDC1 ANKRD31 RGS12 LPL	1.36e-04	59	130	4	EFO_0022289
Disease	triglycerides to total lipids in medium VLDL percentage	PDXDC1 ANKRD31 RGS12 LPL	1.75e-04	63	130	4	EFO_0022335
Disease	cholesterol to total lipids in medium VLDL percentage	PDXDC1 ANKRD31 RGS12 LPL	1.75e-04	63	130	4	EFO_0022239
Disease	Headache	HGF RNF213 BTN2A2 MACF1	1.86e-04	64	130	4	HP_0002315
Disease	sciatic neuropathy (is_implicated_in)	HGF SOD1	1.91e-04	5	130	2	DOID:11446 (is_implicated_in)
Disease	Lateral Sclerosis	PNPLA6 SOD1	1.91e-04	5	130	2	C0154682
Disease	Short rib-polydactyly syndrome, Verma-Naumoff type	DYNC2H1 IFT80	1.91e-04	5	130	2	C0432197
Disease	cholesterol to total lipids in medium LDL percentage	PDXDC1 ANKRD31 LPL	2.26e-04	27	130	3	EFO_0022238
Disease	cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement	PDXDC1 KIF27 RGS12 MSRA LPL MACF1 POC5	2.30e-04	276	130	7	EFO_0004612, EFO_0020943
Disease	Colorectal Carcinoma	SRSF6 POLE ABCB6 CDKL5 ZNF43 ACIN1 DLG3 POLD3 DHRS2 ABCD2 SDCBP2	2.87e-04	702	130	11	C0009402
Disease	Epileptic encephalopathy	GPHN MAGI2 ADSL	3.11e-04	30	130	3	C0543888
Disease	sexual dimorphism measurement	PDXDC1 ANKRD31 SYN3 CFL1 UVSSA TUT7 RBM39 BTN2A2 LPL GMDS MACF1 POC5 B4GALNT3 EPB41L2	3.83e-04	1106	130	14	EFO_0021796
Disease	cholesterol:total lipids ratio, low density lipoprotein cholesterol measurement	PDXDC1 ANKRD31 LPL SYNE2 MACF1	4.53e-04	144	130	5	EFO_0004611, EFO_0020943
Disease	triglyceride measurement, very low density lipoprotein cholesterol measurement	PDXDC1 MSRA LPL SYNE2 MACF1 CTSB	4.88e-04	224	130	6	EFO_0004530, EFO_0008317
Disease	triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement	PDXDC1 ANKRD31 RGS12 MSRA LPL MACF1	5.00e-04	225	130	6	EFO_0008317, EFO_0020947
Disease	benign neoplasm (implicated_via_orthology)	DLG1 DLG3	5.30e-04	8	130	2	DOID:0060072 (implicated_via_orthology)
Disease	triglycerides:total lipids ratio, low density lipoprotein cholesterol measurement	PDXDC1 ANKRD31 LPL SYNE2 MACF1	5.46e-04	150	130	5	EFO_0004611, EFO_0020947
Disease	very low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	PDXDC1 ANKRD31 RGS12 MSRA LPL MACF1	6.85e-04	239	130	6	EFO_0008317, EFO_0020945
Disease	fatty acid measurement	PDXDC1 ANKRD31 KIF27 RGS12 MSRA LPL MACF1 CTSB	7.21e-04	436	130	8	EFO_0005110
Disease	cholesteryl ester 18:3 measurement	PDXDC1 NAV2 POLD3	7.33e-04	40	130	3	EFO_0010346
Disease	mean reticulocyte volume	FLT3 HK1 SYN3 SPTB NEB TFAP4 LPL AFDN PREX1 MEX3B EPB41L2	8.41e-04	799	130	11	EFO_0010701
Disease	hepatocyte growth factor measurement	HGF HAO1 RGS12	9.70e-04	44	130	3	EFO_0006903
Disease	Jeune thoracic dystrophy	DYNC2H1 IFT80	1.03e-03	11	130	2	C0265275
Disease	very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	PDXDC1 ANKRD31 MSRA LPL SYNE2 MACF1	1.15e-03	264	130	6	EFO_0008317, EFO_0020944
Disease	cancer (implicated_via_orthology)	FLT3 POLE RANBP6 DLG1 MACF1 DLG3	1.24e-03	268	130	6	DOID:162 (implicated_via_orthology)
Disease	developmental disorder of mental health (implicated_via_orthology)	DLG1 DLG3 PLXNB3	1.33e-03	49	130	3	DOID:0060037 (implicated_via_orthology)
Disease	RAC-beta serine/threonine-protein kinase measurement	SYN3 EHHADH	1.46e-03	13	130	2	EFO_0021989
Disease	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	ANKRD31 LPL POC5	1.49e-03	51	130	3	EFO_0004340, EFO_0004348, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928
Disease	PR interval	MYCBP2 TFAP4 MAGI2 SYNE2 NAV2 DLG1 MACF1 CHD6	1.62e-03	495	130	8	EFO_0004462
Disease	triglycerides to total lipids in very large VLDL percentage	PDXDC1 ANKRD31 LPL	1.67e-03	53	130	3	EFO_0022340
Disease	alkaline phosphatase measurement	AKAP8 TFAP4 MSRA CTCFL TRAFD1 ADSL NFATC3 LPL MACF1 B4GALNT3 CTSB UTRN	1.80e-03	1015	130	12	EFO_0004533
Disease	Necrosis	LPL CTSB SOD1	1.85e-03	55	130	3	C0027540
Disease	Schizophrenia	HK1 SYN3 CASP4 AMBRA1 RGS12 MSRA MAGI2 PPP3R1 LPL DLG1 DLG3	1.86e-03	883	130	11	C0036341
Disease	very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	PDXDC1 ANKRD31 MSRA LPL SYNE2 MACF1	1.88e-03	291	130	6	EFO_0008317, EFO_0020946
Disease	diffuse idiopathic skeletal hyperostosis	HAO1 POLD3	1.95e-03	15	130	2	EFO_0007236
Disease	cholesteryl esters to total lipids in large VLDL percentage	PDXDC1 ANKRD31 LPL	1.95e-03	56	130	3	EFO_0022250
Disease	low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	PDXDC1 LPL SYNE2 MACF1 POC5	1.96e-03	200	130	5	EFO_0004611, EFO_0020945
Disease	cholesterol:total lipids ratio, intermediate density lipoprotein measurement	PDXDC1 LPL SYNE2 MACF1	2.05e-03	121	130	4	EFO_0008595, EFO_0020943
Disease	triglycerides to total lipids in small VLDL percentage	PDXDC1 ANKRD31 LPL	2.16e-03	58	130	3	EFO_0022338
Disease	cholesterol in IDL measurement	PDXDC1 ANKRD31 LPL	2.16e-03	58	130	3	EFO_0021899
Disease	cholesterol to total lipids in IDL percentage	PDXDC1 LPL MACF1	2.38e-03	60	130	3	EFO_0022233
Disease	reticulocyte measurement	GPHN HK1 SPTB TUT7 ABCB6 NABP1 DNAJA4 UBAC1 LPL SYNE2 AFDN PREX1	2.44e-03	1053	130	12	EFO_0010700
Disease	triglycerides:total lipids ratio, intermediate density lipoprotein measurement	PDXDC1 LPL SYNE2 MACF1	2.45e-03	127	130	4	EFO_0008595, EFO_0020947
Disease	free cholesterol in IDL measurement	PDXDC1 ANKRD31 LPL	2.50e-03	61	130	3	EFO_0022181
Disease	respiratory symptom change measurement, response to placebo	ATF7IP2 NAV2	2.51e-03	17	130	2	EFO_0008344, EFO_0010068
Disease	Vascular Diseases	HGF MYLK	2.51e-03	17	130	2	C0042373
Disease	free cholesterol in very large HDL measurement	PDXDC1 LPL POC5	2.61e-03	62	130	3	EFO_0022273
Disease	unipolar depression	GPHN GALNTL6 CATSPERD DYNC2H1 GRK5 ZKSCAN8 CASP4 RNF213 MSRA MAGI2 AKR1E2 SYNE2 CHD6	2.62e-03	1206	130	13	EFO_0003761
Disease	cholesteryl ester measurement, high density lipoprotein cholesterol measurement	PDXDC1 RGS12 MSRA LPL POC5 CTSB	2.66e-03	312	130	6	EFO_0004612, EFO_0010351
Disease	polyunsaturated fatty acid measurement	PDXDC1 MSRA LPL CTSB	2.74e-03	131	130	4	EFO_0010733
Disease	total cholesterol measurement, high density lipoprotein cholesterol measurement	PDXDC1 RGS12 MSRA LPL POC5 CTSB	2.78e-03	315	130	6	EFO_0004574, EFO_0004612
Disease	carcinoma (implicated_via_orthology)	FLT3 DLG1 DLG3	2.86e-03	64	130	3	DOID:305 (implicated_via_orthology)
Disease	cholesteryl esters to total lipids in medium VLDL percentage	PDXDC1 RGS12 LPL	2.86e-03	64	130	3	EFO_0022253
Disease	total lipids in very large HDL measurement	PDXDC1 LPL POC5	3.12e-03	66	130	3	EFO_0022312
Disease	phospholipids in very large HDL measurement	PDXDC1 LPL POC5	3.12e-03	66	130	3	EFO_0022298
Disease	dense area measurement, mammographic density measurement	MAGI2 ADSL	3.14e-03	19	130	2	EFO_0005941, EFO_0006503
Disease	polycystic kidney disease (biomarker_via_orthology)	CTSB SOD1	3.14e-03	19	130	2	DOID:0080322 (biomarker_via_orthology)
Disease	response to methotrexate, neurotoxicity	PNPLA6 MACF1	3.14e-03	19	130	2	EFO_0011057, GO_0031427
Disease	cholesterol to total lipids in very small VLDL percentage	PDXDC1 RGS12 LPL	3.26e-03	67	130	3	EFO_0022245
Disease	phospholipids:total lipids ratio	PDXDC1 ANKRD31 LPL MACF1 POC5	3.39e-03	227	130	5	EFO_0020946
Disease	fatty acid measurement, linoleic acid measurement	PDXDC1 KIF27 LPL	3.40e-03	68	130	3	EFO_0005110, EFO_0006807
Disease	total cholesterol measurement, hematocrit, stroke, ventricular rate measurement, body mass index, atrial fibrillation, high density lipoprotein cholesterol measurement, coronary artery disease, diastolic blood pressure, triglyceride measurement, systolic blood pressure, heart failure, diabetes mellitus, glucose measurement, mortality, cancer	ANKRD31 LPL POC5	3.54e-03	69	130	3	EFO_0000275, EFO_0000400, EFO_0000712, EFO_0001645, EFO_0003144, EFO_0004340, EFO_0004348, EFO_0004352, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928, MONDO_0004992
Disease	cholesterol in very large HDL measurement	PDXDC1 LPL POC5	3.54e-03	69	130	3	EFO_0022229
Disease	Retinal Degeneration	IFT80 SOD1	3.83e-03	21	130	2	C0035304
Disease	vitiligo (is_implicated_in)	HGF NLRP1	3.83e-03	21	130	2	DOID:12306 (is_implicated_in)
Disease	docosahexaenoic acid to total fatty acids percentage	PDXDC1 LPL	3.83e-03	21	130	2	EFO_0022262
Disease	Hepatitis, Chronic	HGF SOD1	4.20e-03	22	130	2	C0019189
Disease	Chronic active hepatitis	HGF SOD1	4.20e-03	22	130	2	C0520463
Disease	Chronic Persistent Hepatitis	HGF SOD1	4.20e-03	22	130	2	C0149519
Disease	Cryptogenic Chronic Hepatitis	HGF SOD1	4.20e-03	22	130	2	C0524611
Disease	free cholesterol to total lipids in large LDL percentage	PDXDC1 LPL MACF1	4.31e-03	74	130	3	EFO_0022280

Protein segments in the cluster

Peptide	Gene	Start	Entry
GDDGTHDKGLKICRT	ACIN1	906	Q9UKV3
HDKIRKGCVITISGR	ACOT7	281	O00154
AAVGAHDACRDAKEK	AFDN	1756	P55196
CETGKRHSIKELEEI	FAM228A	81	Q86W67
EEVKDRCTLAEKLGG	CFL1	141	P23528
KILRGQDHCGIESEV	CTSB	311	P07858
ELHVGKCKIEFLTGE	CATSPERD	381	Q86XM0
EKDGVCREKDHRSPS	CTCFL	31	Q8NI51
AIKGKVIDVDHGIIC	ABCD2	466	Q9UBJ2
AGVIDAIRKHCVEGK	B4GALNT3	886	Q6L9W6
CGTAHEKGVPKARSE	AKAP8	631	O43823
DVDIACRSVLHKDIG	ADGRB3	1191	O60242
GILEGICGTVHDEKK	CASP4	211	P49662
VREVAEKGKHCILDV	DLG1	796	Q12959
GKVVECLDHARGKSQ	CLK3	316	P49761
VIKDGCIVERGRHEA	ABCB6	796	Q9NP58
EEFCAVVGGLDIHKK	PPP3R1	151	P63098
KAGEVIKHGDLRCVR	DNAJA4	291	Q8WW22
ACKTDGDGRVVEGKH	CYTH4	336	Q9UIA0
EVKTGKCVHSLIGHR	AMBRA1	81	Q9C0C7
CETKDEGGKRLEAVH	ATG2A	941	Q2TAZ0
VDKESGRCKAIIDHF	CHML	411	P26374
IKDDVIEECNKHGGV	RBM39	446	Q14498
GHDIKRGECVLAKGT	GPHN	461	Q9NQX3
KEVCSEKTGHAEVVR	MSRA	106	Q9UJ68
LSEAKVETICHRKEG	ANKRD31	296	Q8N7Z5
RETAIEVGKGCDFHI	POC5	81	Q8NA72
CSHIGVLKALEEAGV	PNPLA6	991	Q8IY17
VKDCGADVHLRALDG	ESPNL	191	Q6ZVH7
RDGKALCKDTGHFEV	MYLK	756	Q15746
KCVKQGGIVDKDLRH	MAGI2	96	Q86UL8
ADRCGKLKVGDHISA	MAGI3	891	Q5TCQ9
VGRCKETGKVHVTVD	GMDS	306	O60547
AKKGERECHIVVLTD	KCTD20	251	Q7Z5Y7
EHTGKCRVSGVVLVD	MTO1	166	Q9Y2Z2
KKELSSCDGHDGLRR	ESPN	486	B1AK53
VCTRADGGDIHIHKK	KIAA0930	121	Q6ICG6
AKDSEGVDIKLGVCA	EPB41L2	411	O43491
IDHTIKAIVICGAEG	EHHADH	41	Q08426
DEKGNTVIVGAKECH	KIF27	161	Q86VH2
ISKEEVRVHIGRGEC	PLXNB3	1181	Q9ULL4
CLRKVTGLGGEHKED	KSR1	166	Q8IVT5
GLGDVDQLVKCSHER	LPL	256	P06858
AVGHTDKIGRLKELC	PDXDC1	246	Q6P996
AVGHTDKIGRLKELC	PDXDC2P	246	Q6P474
VLEDEKGRGKHSNCI	NLRP1	636	Q9C000
KGILRGDDAREAVKH	HAO1	236	Q9UJM8
IKACKTEADGRVVEG	CYTH1	336	Q15438
AAVEVGDAAEVKRCK	POLE	781	Q07864
HDVHGRGDEKCKQVL	HGF	551	P14210
KGFKATDCVGHDVVT	HK1	621	P19367
CGKSVERQHKLEEAL	MACF1	6646	Q9UPN3
TGKIECEIKINHEGE	RBBP7	111	Q16576
HGKVVKICDFGLARD	FLT3	821	P36888
KNHRTVCELLGKEVE	DYNC2H1	1766	Q8NCM8
VSGDHCRIVVDEKSG	CHFR	56	Q96EP1
GRVEKSVEAHCGAVL	IFT80	96	Q9P2H3
IKRKSEEGNVHDGCK	GCNT7	341	Q6ZNI0
ECGKHDRDLLIGTAK	CHD6	1576	Q8TD26
AEAKHEGARKEVLGL	CROCC2	1191	H7BZ55
KDDEIRDKCGGDAVH	TMEM63B	136	Q5T3F8
GCQVAKQHVRDGRKE	REXO1L1P	466	Q8IX06
AVAERGKHCILDVSG	DLG3	711	Q92796
KCHGTKEEGDREITS	BARHL2	206	Q9NY43
QRIGKTECRNKHEGI	ATF7IP2	346	Q5U623
KIKSEGTCLHRLEEE	MAP3K12	396	Q12852
CKRDPHVKIEGKDTD	MALSU1	151	Q96EH3
LVKGAKLHDRESGEE	CCDC168	2501	Q8NDH2
RLGCQEEGAAEVKRH	GRK5	431	P34947
VGVCRHSVERKGEVL	BTN2A2	396	Q8WVV5
EGAYGVVLKCRHKET	CDKL5	21	O76039
GVVVADGDHDKLSKR	C4orf54	1301	D6RIA3
SVAGIVCHVGKAEDR	DHRS2	86	Q13268
ELEEICKAHGTVKDL	SART3	816	Q15020
KSEDGAIHVIERRCK	SEC14L1	46	Q92503
GGEEAEIRFCEHKRL	DHX9	931	Q08211
GRLHCKIDKVNEIVE	PSMD6	341	Q15008
EREKLHGCIDVGLSV	OSBPL3	91	Q9H4L5
CRKEGGDLTSIHTIE	MRC1	391	P22897
EHVAEIVGRQGCKIK	MEX3B	76	Q6ZN04
HGATGTELRLDICVK	GALNTL6	471	Q49A17
LDICAVKAVHSKDGR	SYN3	346	O14994
DCKRVLDGVKAELHV	UTRN	1446	P46939
NGKDLCGERVIVEHA	SRSF4	56	Q08170
HVAREADEGCKKPLE	RPRD1B	91	Q9NQG5
THGGCLKRAIDLKAE	UVSSA	356	Q2YD98
TKDGHEVRSCKVADK	NABP1	36	Q96AH0
KDLKTHPEVCGREGE	TRAFD1	126	O14545
LIKGHGEDCIEAEEK	SYNE2	6731	Q8WXH0
KAGGSRQDCHEKIRV	ADSL	391	P30566
ECSARKEGGRHVKIV	NAV2	2006	Q8IVL1
HGGIKKVCFKVAEED	PREX1	1141	Q8TCU6
EEEAIKVDLHEGCGR	MYCBP2	4306	O75592
NGKELCGERVIVEHA	SRSF6	56	Q13247
GHSCHKVAVVREDKL	POLD3	71	Q15054
IECISHIGLAVGKEK	RANBP6	566	O60518
RTLVVHEKADDLGKG	SOD1	116	P00441
VREIHLCKDERGKTG	SDCBP2	106	Q9H190
HNEREVGAGIRCKIK	AKR1E2	41	Q96JD6
TIHCLEILEGERGKE	CCDC54	151	Q8NEL0
LKRKCVGHEEDVEGA	CDCA4	6	Q9BXL8
ACHTRGLDGIKELEI	NCAPD2	1291	Q15021
VDEEKARCLEGIGGH	TRIM74	186	Q86UV6
DVKHVFRLCGTDEKI	RNF213	1056	Q63HN8
IIHTGEKSYKREECG	ZNF724	246	A8MTY0
SHEDVVKLIGKCSGV	RGS12	76	O14924
AAVKDGKSITHEGRE	ELAC2	276	Q9BQ52
GERHLVTCKGATVEA	NXNL2	6	Q5VZ03
GRKCKLLLTSVHEDD	SPEG	1021	Q15772
EKIAVHCTVRGAKAE	RPL11	66	P62913
HCTVRGAKAEEILEK	RPL11	71	P62913
ERVKHEKGYAICGLA	WDHD1	266	O75717
KTKDGHEVRTCKVAD	NABP2	31	Q9BQ15
GGEVKCEFEHKVIKE	TTC3	731	P53804
LKHRRTCGEVIVKGA	ZNF281	361	Q9Y2X9
VEGKIIREKCQGAHI	NFATC3	646	Q12968
GSKVKDVCEDLVRHG	POLR3B	966	Q9NW08
CARGPKASKHAGEEV	PRRG4	21	Q9BZD6
AGIKTHVEKEDGEAR	SNW1	336	Q13573
EGKRVGKVIDHAIET	SPTB	286	P11277
KEIECSIAGAHEKIA	THOC7	86	Q6I9Y2
KGSGFRCIHIGEKVD	TOB1	51	P50616
DCKEVIGGTNHTLER	ZNFX1	1871	Q9P2E3
KDHKSVDECKVHRGG	ZNF43	116	P17038
HERVCKSDETGEKSG	ZNF180	186	Q9UJW8
VDEEKARCLEGIGGH	TRIM73	186	Q86UV7
GKVLRLHICASDGAE	UBAC1	11	Q9BSL1
EERILRGHGADVKCV	WDR33	236	Q9C0J8
EDVKECGKHVERALL	TUT7	906	Q5VYS8
VDEEKARCLEGIGGH	TRIM50	186	Q86XT4
HFRKTEKEVIGGLCS	TFAP4	16	Q01664
AAKCNGDVIRGLEHE	ZKSCAN8	286	Q15776
IEEAKRKDGVVLVHC	DUSP19	136	Q8WTR2
GDVAKTICHVDEKAK	NEB	141	P20929