Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L EGF TBC1D3D MYCBP2 CDC42EP2 FGD1 RPGR TBC1D3I ARHGEF25 TBC1D3G GDPGP1 TBC1D3C TBC1D3B SYDE1 TBC1D3K TBC1D3F	5.46e-16	507	62	19	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L EGF TBC1D3D MYCBP2 CDC42EP2 FGD1 RPGR TBC1D3I ARHGEF25 TBC1D3G GDPGP1 TBC1D3C TBC1D3B SYDE1 TBC1D3K TBC1D3F	5.46e-16	507	62	19	GO:0030695
GeneOntologyMolecularFunction	GTPase activator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D CDC42EP2 TBC1D3I TBC1D3G TBC1D3C TBC1D3B SYDE1 TBC1D3K TBC1D3F	2.64e-12	279	62	13	GO:0005096
GeneOntologyMolecularFunction	enzyme regulator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L EGF TBC1D3D MYCBP2 CDC42EP2 FGD1 RPGR TBC1D3I ARHGEF25 TBC1D3G GDPGP1 TBC1D3C TBC1D3B SYDE1 SLX4 TBC1D3K TBC1D3F SPINK5	7.15e-10	1418	62	21	GO:0030234
GeneOntologyMolecularFunction	enzyme activator activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L EGF TBC1D3D CDC42EP2 TBC1D3I TBC1D3G TBC1D3C TBC1D3B SYDE1 SLX4 TBC1D3K TBC1D3F	1.06e-09	656	62	15	GO:0008047
GeneOntologyMolecularFunction	molecular function activator activity	TBC1D3E TBC1D3 CRLF1 TBC1D3H TBC1D3L EGF TBC1D3D CDC42EP2 TBC1D3I F2 TBC1D3G TBC1D3C TBC1D3B SYDE1 SLX4 TBC1D3K TBC1D3F	1.29e-07	1233	62	17	GO:0140677
GeneOntologyMolecularFunction	guanyl-nucleotide exchange factor activity	EGF MYCBP2 FGD1 RPGR ARHGEF25 GDPGP1	8.04e-05	231	62	6	GO:0005085
GeneOntologyMolecularFunction	peroxisome proliferator activated receptor binding	ASXL1 ASXL2	1.92e-03	21	62	2	GO:0042975
GeneOntologyBiologicalProcess	activation of GTPase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B SYDE1 TBC1D3K TBC1D3F	3.57e-16	109	61	12	GO:0090630
GeneOntologyBiologicalProcess	positive regulation of GTPase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B SYDE1 TBC1D3K TBC1D3F	5.98e-12	244	61	12	GO:0043547
GeneOntologyBiologicalProcess	regulation of GTPase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D FGD1 TBC1D3I TBC1D3G TBC1D3C TBC1D3B SYDE1 TBC1D3K TBC1D3F	1.41e-11	335	61	13	GO:0043087
GeneOntologyBiologicalProcess	positive regulation of hydrolase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G BBC3 TBC1D3C TBC1D3B SYDE1 TBC1D3K TBC1D3F NLRP6	1.56e-10	499	61	14	GO:0051345
GeneOntologyBiologicalProcess	positive regulation of catalytic activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L EGF TBC1D3D NEURL1 ASXL2 TBC1D3I F2 TBC1D3G BBC3 TBC1D3C TBC1D3B SYDE1 TBC1D3K TBC1D3F NLRP6	5.33e-10	1028	61	18	GO:0043085
GeneOntologyBiologicalProcess	regulation of hydrolase activity	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D FGD1 TBC1D3I TBC1D3G BBC3 TBC1D3C TBC1D3B SYDE1 TBC1D3K TBC1D3F SPINK5 NLRP6	3.41e-09	878	61	16	GO:0051336
GeneOntologyBiologicalProcess	positive regulation of molecular function	TBC1D3E TBC1D3 TBC1D3H TBC1D3L EGF TBC1D3D NEURL1 ASXL2 TBC1D3I F2 TBC1D3G BBC3 TBC1D3C TBC1D3B SYDE1 TBC1D3K TBC1D3F NLRP6	9.17e-08	1430	61	18	GO:0044093
GeneOntologyBiologicalProcess	positive regulation of mRNA splicing, via spliceosome	RBMY1A1 RBMY1C RBMY1D RBMY1E	8.60e-06	44	61	4	GO:0048026
GeneOntologyBiologicalProcess	positive regulation of mRNA processing	RBMY1A1 RBMY1C RBMY1D RBMY1E	1.33e-05	49	61	4	GO:0050685
GeneOntologyBiologicalProcess	positive regulation of RNA splicing	RBMY1A1 RBMY1C RBMY1D RBMY1E	3.62e-05	63	61	4	GO:0033120
GeneOntologyCellularComponent	PR-DUB complex	ASXL1 ASXL2	5.01e-05	4	61	2	GO:0035517
GeneOntologyCellularComponent	PcG protein complex	ASXL1 MTF2 ASXL2	4.72e-04	52	61	3	GO:0031519
Domain	TBC	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	3.31e-16	49	59	10	SM00164
Domain	RabGAP-TBC	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	7.79e-16	53	59	10	PF00566
Domain	TBC_RABGAP	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	1.16e-15	55	59	10	PS50086
Domain	Rab-GTPase-TBC_dom	TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	1.16e-15	55	59	10	IPR000195
Domain	RBM1CTR	RBMY1A1 RBMY1D RBMY1E	1.66e-06	8	59	3	PF08081
Domain	RBM1CTR	RBMY1A1 RBMY1D RBMY1E	1.66e-06	8	59	3	IPR012604
Domain	HARE-HTH	ASXL1 ASXL2	2.94e-05	3	59	2	PF05066
Domain	ASXH	ASXL1 ASXL2	2.94e-05	3	59	2	PF13919
Domain	PHD_3	ASXL1 ASXL2	2.94e-05	3	59	2	PF13922
Domain	ASX-like_PHD	ASXL1 ASXL2	2.94e-05	3	59	2	IPR026905
Domain	ASX/ASX-like	ASXL1 ASXL2	2.94e-05	3	59	2	IPR024811
Domain	ASXH	ASXL1 ASXL2	2.94e-05	3	59	2	IPR028020
Domain	HB1/Asxl_HTH	ASXL1 ASXL2	2.94e-05	3	59	2	IPR007759
Domain	RCC1	MYCBP2 RPGR	1.80e-03	20	59	2	PF00415
Domain	RCC1_1	MYCBP2 RPGR	1.98e-03	21	59	2	PS00625
Domain	RCC1_2	MYCBP2 RPGR	1.98e-03	21	59	2	PS00626
Domain	RCC1_3	MYCBP2 RPGR	1.98e-03	21	59	2	PS50012
Domain	Reg_chr_condens	MYCBP2 RPGR	2.18e-03	22	59	2	IPR000408
Domain	-	MYCBP2 RPGR	2.18e-03	22	59	2	2.130.10.30
Domain	RCC1/BLIP-II	MYCBP2 RPGR	2.38e-03	23	59	2	IPR009091
Domain	TRYPSIN_SER	KLK9 F2 PRSS36	2.89e-03	90	59	3	IPR033116
Domain	ZF_PHD_2	ASXL1 MTF2 ASXL2	3.37e-03	95	59	3	PS50016
Domain	ZF_PHD_1	ASXL1 MTF2 ASXL2	3.47e-03	96	59	3	PS01359
Domain	TRYPSIN_HIS	KLK9 F2 PRSS36	4.23e-03	103	59	3	IPR018114
Domain	TRYPSIN_SER	KLK9 F2 PRSS36	4.59e-03	106	59	3	PS00135
Domain	TRYPSIN_HIS	KLK9 F2 PRSS36	4.71e-03	107	59	3	PS00134
Domain	Peptidase_S1A	KLK9 F2 PRSS36	5.48e-03	113	59	3	IPR001314
Domain	TRYPSIN_DOM	KLK9 F2 PRSS36	5.75e-03	115	59	3	PS50240
Domain	Tryp_SPc	KLK9 F2 PRSS36	6.04e-03	117	59	3	SM00020
Domain	Trypsin	KLK9 F2 PRSS36	6.62e-03	121	59	3	PF00089
Domain	Trypsin_dom	KLK9 F2 PRSS36	6.62e-03	121	59	3	IPR001254
Domain	Peptidase_S1_PA	KLK9 F2 PRSS36	6.93e-03	123	59	3	IPR009003
Domain	Nucleotide-bd_a/b_plait	RBMY1A1 R3HCC1 RBMY1D RBMY1E	8.94e-03	258	59	4	IPR012677
Pathway	WP_17Q12_COPY_NUMBER_VARIATION_SYNDROME	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K	2.55e-11	99	46	9	M46448
Pubmed	TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12.	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	2.26e-31	11	62	11	16863688
Pubmed	DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.	TBC1D3E TBC1D3 TBC1D3H TBC1D3D TBC1D3G TBC1D3B TBC1D3F	6.61e-11	74	62	7	16625196
Pubmed	A Y chromosome gene family with RNA-binding protein homology: candidates for the azoospermia factor AZF controlling human spermatogenesis.	RBMY1A1 RBMY1C RBMY1D RBMY1E	3.19e-10	7	62	4	8269511
Pubmed	Structure and organization of the RBMY genes on the human Y chromosome: transposition and amplification of an ancestral autosomal hnRNPG gene.	RBMY1A1 RBMY1C RBMY1D RBMY1E	4.48e-09	12	62	4	9598316
Pubmed	PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer.	TBC1D3 TBC1D3D TBC1D3F	2.16e-08	4	62	3	12359748
Pubmed	Identification of novel sequences in the repertoire of hypervariable TRE17 genes from immortalized nonmalignant and malignant human keratinocytes.	TBC1D3 TBC1D3D TBC1D3F	2.16e-08	4	62	3	8406013
Pubmed	The Tre2 (USP6) oncogene is a hominoid-specific gene.	TBC1D3 TBC1D3D TBC1D3C	5.38e-08	5	62	3	12604796
Pubmed	An RBM homologue maps to the mouse Y chromosome and is expressed in germ cells.	RBMY1A1 RBMY1D RBMY1E	5.38e-08	5	62	3	8817321
Pubmed	Human TRE17 oncogene is generated from a family of homologous polymorphic sequences by single-base changes.	TBC1D3 TBC1D3D TBC1D3F	5.38e-08	5	62	3	8471161
Pubmed	Human RBMY regulates germline-specific splicing events by modulating the function of the serine/arginine-rich proteins 9G8 and Tra2-{beta}.	RBMY1A1 RBMY1D RBMY1E	5.38e-08	5	62	3	20016065
Pubmed	The role of human and mouse Y chromosome genes in male infertility.	RBMY1A1 RBMY1D RBMY1E	5.38e-08	5	62	3	11097427
Pubmed	Rapid evolution of mouse Y centromere repeat DNA belies recent sequence stability.	RBMY1A1 RBMY1D RBMY1E	5.38e-08	5	62	3	19737860
Pubmed	The behavior of the X- and Y-chromosomes in the oocyte during meiotic prophase in the B6.Y(TIR)sex-reversed mouse ovary.	RBMY1A1 RBMY1D RBMY1E	1.07e-07	6	62	3	18239052
Pubmed	Identification of target messenger RNA substrates for mouse RBMY.	RBMY1A1 RBMY1D RBMY1E	1.07e-07	6	62	3	18492746
Pubmed	Meiotic sex chromosome inactivation in male mice with targeted disruptions of Xist.	RBMY1A1 RBMY1D RBMY1E	1.07e-07	6	62	3	12356914
Pubmed	Mouse homologues of the human AZF candidate gene RBM are expressed in spermatogonia and spermatids, and map to a Y chromosome deletion interval associated with a high incidence of sperm abnormalities.	RBMY1A1 RBMY1D RBMY1E	1.07e-07	6	62	3	9499427
Pubmed	RBMY, a male germ cell-specific RNA-binding protein, activated in human liver cancers and transforms rodent fibroblasts.	RBMY1A1 RBMY1D RBMY1E	1.07e-07	6	62	3	15184870
Pubmed	Does Rbmy have a role in sperm development in mice?	RBMY1A1 RBMY1D RBMY1E	1.07e-07	6	62	3	15051956
Pubmed	Degeneracy in human multicopy RBM (YRRM), a candidate spermatogenesis gene.	RBMY1A1 RBMY1D RBMY1E	1.88e-07	7	62	3	8875892
Pubmed	RNA-binding motif protein 15 binds to the RNA transport element RTE and provides a direct link to the NXF1 export pathway.	RBMY1A1 RBMY1D RBMY1E	1.88e-07	7	62	3	17001072
Pubmed	The roles of RNA-binding proteins in spermatogenesis and male infertility.	RBMY1A1 RBMY1D RBMY1E	1.88e-07	7	62	3	10377282
Pubmed	Y chromosome short arm-Sxr recombination in XSxr/Y males causes deletion of Rbm and XY female sex reversal.	RBMY1A1 RBMY1D RBMY1E	3.00e-07	8	62	3	7479793
Pubmed	Mice with Y chromosome deletion and reduced Rbm genes on a heterozygous Dazl1 null background mimic a human azoospermic factor phenotype.	RBMY1A1 RBMY1D RBMY1E	6.42e-07	10	62	3	10601091
Pubmed	Characterisation of the coding sequence and fine mapping of the human DFFRY gene and comparative expression analysis and mapping to the Sxrb interval of the mouse Y chromosome of the Dffry gene.	RBMY1A1 RBMY1D RBMY1E	6.42e-07	10	62	3	9384609
Pubmed	The role of Dby mRNA in early development of male mouse zygotes.	RBMY1A1 RBMY1D RBMY1E	1.17e-06	12	62	3	20543856
Pubmed	GASZ promotes germ cell derivation from embryonic stem cells.	RBMY1A1 RBMY1D RBMY1E	1.52e-06	13	62	3	23816659
Pubmed	Absence of mDazl produces a final block on germ cell development at meiosis.	RBMY1A1 RBMY1D RBMY1E	1.94e-06	14	62	3	14611631
Pubmed	Evolutionary strata on the mouse X chromosome correspond to strata on the human X chromosome.	RBMY1A1 RBMY1D RBMY1E	2.42e-06	15	62	3	14762062
Pubmed	ASXL1/2 mutations and myeloid malignancies.	ASXL1 ASXL2	3.13e-06	2	62	2	36068610
Pubmed	ASXL2 is essential for haematopoiesis and acts as a haploinsufficient tumour suppressor in leukemia.	ASXL1 ASXL2	3.13e-06	2	62	2	28516957
Pubmed	Loss of maternal Trim28 causes male-predominant early embryonic lethality.	RBMY1A1 RBMY1D RBMY1E	3.60e-06	17	62	3	28115466
Pubmed	Sex differences in sex chromosome gene expression in mouse brain.	RBMY1A1 RBMY1D RBMY1E	4.32e-06	18	62	3	12023983
Pubmed	Additional sex comb-like (ASXL) proteins 1 and 2 play opposite roles in adipogenesis via reciprocal regulation of peroxisome proliferator-activated receptor {gamma}.	ASXL1 ASXL2	9.37e-06	3	62	2	21047783
Pubmed	Characterization of Asxl1, a murine homolog of Additional sex combs, and analysis of the Asx-like gene family.	ASXL1 ASXL2	9.37e-06	3	62	2	16412590
Pubmed	Diversity of human copy number variation and multicopy genes.	TBC1D3E TBC1D3G	9.37e-06	3	62	2	21030649
Pubmed	Role of FGD1, a Cdc42 guanine nucleotide exchange factor, in epidermal growth factor-stimulated c-Jun NH2-terminal kinase activation and cell migration.	EGF FGD1	9.37e-06	3	62	2	21212517
Pubmed	Functional proteomics of the epigenetic regulators ASXL1, ASXL2 and ASXL3: a convergence of proteomics and epigenetics for translational medicine.	ASXL1 ASXL2	9.37e-06	3	62	2	25835095
Pubmed	ASXL2 mutations are frequently found in pediatric AML patients with t(8;21)/ RUNX1-RUNX1T1 and associated with a better prognosis.	ASXL1 ASXL2	9.37e-06	3	62	2	28063196
Pubmed	Familial and Somatic BAP1 Mutations Inactivate ASXL1/2-Mediated Allosteric Regulation of BAP1 Deubiquitinase by Targeting Multiple Independent Domains.	ASXL1 ASXL2	9.37e-06	3	62	2	29284740
Pubmed	Kinetic Characterization of ASXL1/2-Mediated Allosteric Regulation of the BAP1 Deubiquitinase.	ASXL1 ASXL2	9.37e-06	3	62	2	33731362
Pubmed	Understanding the phenotypic spectrum of ASXL-related disease: Ten cases and a review of the literature.	ASXL1 ASXL2	9.37e-06	3	62	2	33751773
Pubmed	MRNIP interacts with sex body chromatin to support meiotic progression, spermatogenesis, and male fertility in mice.	RBMY1A1 RBMY1D RBMY1E	1.36e-05	26	62	3	35920200
Pubmed	BAP1/ASXL complex modulation regulates epithelial-mesenchymal transition during trophoblast differentiation and invasion.	ASXL1 ASXL2	1.87e-05	4	62	2	34170818
Pubmed	Oncogenic Truncations of ASXL1 Enhance a Motif for BRD4 ET-Domain Binding.	ASXL1 ASXL2	1.87e-05	4	62	2	34536441
Pubmed	Epidermal growth factor regulates hematopoietic regeneration after radiation injury.	EGF BBC3	6.53e-05	7	62	2	23377280
Pubmed	Molecular interactions and functional interference between vitronectin and transforming growth factor-beta.	EGF F2	8.69e-05	8	62	2	11796824
Pubmed	The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer.	ASXL1 ASXL2	1.12e-04	9	62	2	26416890
Pubmed	Additional sex combs-like family genes are required for normal cardiovascular development.	ASXL1 ASXL2	1.12e-04	9	62	2	24860998
Pubmed	Lineage-specific biology revealed by a finished genome assembly of the mouse.	RBMY1A1 RBMY1D RBMY1E	1.32e-04	55	62	3	19468303
Pubmed	ASXL3 bridges BRD4 to BAP1 complex and governs enhancer activity in small cell lung cancer.	ASXL1 ASXL2	1.39e-04	10	62	2	32669118
Pubmed	Diphthamide deficiency promotes association of eEF2 with p53 to induce p21 expression and neural crest defects.	DPH1 BBC3	1.39e-04	10	62	2	38671004
Pubmed	The deubiquitinating enzyme BAP1 regulates cell growth via interaction with HCF-1.	ASXL1 ASXL2	1.39e-04	10	62	2	19815555
Pubmed	T-STAR/ETOILE: a novel relative of SAM68 that interacts with an RNA-binding protein implicated in spermatogenesis.	RBMY1A1 RBMY1C	1.39e-04	10	62	2	10332027
Pubmed	An abundance of X-linked genes expressed in spermatogonia.	RBMY1A1 RBMY1D RBMY1E	1.63e-04	59	62	3	11279525
Pubmed	WT1 targets Gas1 to maintain nephron progenitor cells by modulating FGF signals.	CRLF1 GAS1	2.04e-04	12	62	2	25804736
Pubmed	RBMY, a probable human spermatogenesis factor, and other hnRNP G proteins interact with Tra2beta and affect splicing.	RBMY1A1 RBMY1C	2.41e-04	13	62	2	10749975
Pubmed	Loss of the tumor suppressor BAP1 causes myeloid transformation.	ASXL1 ASXL2	2.41e-04	13	62	2	22878500
Pubmed	The ubiquitin carboxyl hydrolase BAP1 forms a ternary complex with YY1 and HCF-1 and is a critical regulator of gene expression.	ASXL1 ASXL2	3.69e-04	16	62	2	20805357
Pubmed	Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy.	ASXL1 ASXL2	5.82e-04	20	62	2	29785026
Pubmed	Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7.	RBMY1A1 RBMY1D RBMY1E	6.64e-04	95	62	3	24029230
Pubmed	Fanconi Anemia	FAAP100 SLX4	7.72e-04	23	62	2	20301575
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	DPH1 EGF ICAM5 R3HCC1 WDR90 RPGR ENKD1	1.27e-03	925	62	7	28986522
Pubmed	GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.	TBC1D3 TBC1D3F	1.50e-03	32	62	2	23535730
Pubmed	A human MAP kinase interactome.	CDC42EP2 NCKAP5 EXTL3 ENKD1 TBC1D3F	1.76e-03	486	62	5	20936779
Cytoband	Ensembl 112 genes in cytogenetic band chr17q12	TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	1.27e-16	149	62	11	chr17q12
Cytoband	17q12	TBC1D3 TBC1D3H TBC1D3C TBC1D3B TBC1D3F	2.47e-07	99	62	5	17q12
Cytoband	Yq11.223	RBMY1A1 RBMY1D RBMY1E	2.79e-04	93	62	3	Yq11.223
GeneFamily	RNA binding motif containing	RBMY1A1 RBMY1C RBMY1D RBMY1E	5.86e-04	213	33	4	725
CoexpressionAtlas	Endoderm Differentiated Cells-reprogram_OSKM-L_vs_Endoderm Differentiated Cells-reprogram_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D ZSWIM5 ARHGEF25 TBC1D3G BBC3 TBC1D3C TBC1D3B TBC1D3K TBC1D3F	5.63e-13	213	59	12	PCBC_ratio_DE_from-OSKM-L_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlas	Endoderm Differentiated Cells-method_mRNA_vs_Endoderm Differentiated Cells-method_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D ZSWIM5 ARHGEF25 TBC1D3G BBC3 TBC1D3C TBC1D3B TBC1D3K TBC1D3F	5.63e-13	213	59	12	PCBC_ratio_DE_from-mRNA_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 15_vs_Mesoderm Day 30-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	3.09e-12	90	59	9	PCBC_ratio_MESO-15_vs_MESO-30_cfr-2X-p05
CoexpressionAtlas	DE cord blood_vs_DE blastocyst-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L EGF TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F SPINK5	5.80e-11	242	59	11	PCBC_ratio_DE cord blood_vs_DE blastocyst_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5-reprogram_OSKM-L_vs_Mesoderm Day 5-reprogram_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D WDR90 TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	4.98e-09	281	59	10	PCBC_ratio_MESO-5_from-OSKM-L_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5-method_mRNA_vs_Mesoderm Day 5-method_NA-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D WDR90 TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	4.98e-09	281	59	10	PCBC_ratio_MESO-5_from-mRNA_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	2.32e-07	320	59	9	PCBC_ratio_MESO-5_vs_DE_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 15_vs_Mesoderm Day 5-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D CD248 CDC42EP2 F2 TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	2.58e-05	1049	59	12	PCBC_ratio_MESO-15_vs_MESO-5_cfr-2X-p05
CoexpressionAtlas	Ectoderm Differentiated Cells_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05	ASXL1 TBC1D3 TBC1D3H TBC1D3L EGF TBC1D3D BARHL1 GAS1 TBC1D3G TBC1D3C TBC1D3B ENKD1 TBC1D3K TBC1D3F	3.67e-05	1466	59	14	PCBC_ratio_ECTO_vs_SC_cfr-2X-p05
CoexpressionAtlas	Mesoderm Day 5_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05	ASXL1 TBC1D3 TBC1D3H TBC1D3L EGF TBC1D3D ZSWIM5 TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	6.48e-05	1153	59	12	PCBC_ratio_MESO-5_vs_SC_cfr-2X-p05
CoexpressionAtlas	Ectoderm Differentiated Cells_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05	TBC1D3 TBC1D3H TBC1D3L TBC1D3D BARHL1 GAS1 TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F	1.59e-04	1075	59	11	PCBC_ratio_ECTO_vs_DE_cfr-2X-p05
CoexpressionAtlas	ratio_induced-Ectoderm_vs_StemCell_top-relative-expression-ranked_1000	ASXL1 TBC1D3 TBC1D3H FMN1 BARHL1 GAS1 NEURL1 TBC1D3C TBC1D3B TBC1D3F	3.52e-04	986	59	10	PCBC_ratio_ECTO_vs_SC_1000
ToppCell	facs-Lung-Endomucin-3m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEURL1 GDPGP1 CD163 NLRP6	7.42e-05	166	60	4	a2ce44702a0cd5fa5872cac3302d3c451205feef
ToppCell	facs-Lung-Endomucin-3m-Myeloid-myeloid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEURL1 GDPGP1 CD163 NLRP6	7.42e-05	166	60	4	0f641302a6b71c4badaaf20f51162bfc2386b167
ToppCell	wk_20-22-Hematologic-Meg-ery-Platelet\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	LY6G6F EGF ICAM5 BBC3	1.04e-04	181	60	4	724efbc200e8388829bc7d81830c2689a95fa838
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ZNF469 CILP CD248 GAS1	1.06e-04	182	60	4	e9fcae9d03a6faf85b91882c5da699037bc61aeb
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CILP CD248 GAS1 ARHGEF25	1.08e-04	183	60	4	06a68fa2be36448064f4668be24a5b85ad85c6e8
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CILP WDR90 F2 CD163	1.08e-04	183	60	4	6c1d7ce60e67bf1df364a4e177c351e7313eb41f
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-Stromal_4_(MMP1+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SHF CILP ARHGEF25 SYDE1	1.08e-04	183	60	4	269afec240a756eec3bbae5f30ec784281af3433
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CRLF1 CILP CD248 GAS1	1.10e-04	184	60	4	d754c3de621429b220ae4ac426cdfc619e848462
ToppCell	metastatic_Lymph_Node-Fibroblasts-COL14A1+_matrix_FBs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	CRACD CILP CD248 GAS1	1.13e-04	185	60	4	506eee2c1b6e8acec3aa8b2c66868010006c4c14
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CILP CD248 GAS1 ARHGEF25	1.13e-04	185	60	4	1b990e3089772be2b38c6d7ea0d1bf22461ae3ea
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CRLF1 CILP CD248 GAS1	1.20e-04	188	60	4	6c6486cae9a8f2f8200598cb4bfd3fd513eb28a3
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Subpleural_fibroblasts-Subpleural_fibroblasts_L.2.1.5.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CILP CD248 GAS1 ARHGEF25	1.30e-04	192	60	4	859a32c9e4ed6961897b2ccaecde73a599471df9
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Subpleural_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CILP CD248 GAS1 ARHGEF25	1.30e-04	192	60	4	89e1da82fa2069dac7adb9cba3e8b6c0179e0dc5
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRLF1 CILP CD248 GAS1	1.33e-04	193	60	4	eff718664fe0aaf89050efd9cc7b6dfb1df46666
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CILP CD248 GAS1 ARHGEF25	1.35e-04	194	60	4	ca1f24070424b44b7a442e4fca761ebfbe24b063
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FMN1 PRSS36 CD163 ANKS1A	1.35e-04	194	60	4	45708cb2cafde10bf4e4798b81d47c3b1f6aaa14
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CILP MYCBP2 GAS1 XRN1	1.38e-04	195	60	4	5c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell	metastatic_Lymph_Node-Fibroblasts\|metastatic_Lymph_Node / Location, Cell class and cell subclass	CRACD CILP CD248 GAS1	1.41e-04	196	60	4	275e153347caf94edc0c50021bbab49c8696fecb
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CRLF1 CILP CD248 GAS1	1.44e-04	197	60	4	71786e9432e2d649f5d86f639abb25e7102deb67
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	CILP CD248 GAS1 SYDE1	1.46e-04	198	60	4	5cfd1c030c0940136a397b5a4b5d6ecbaecf72eb
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Hematopoietic-Megakaryocytic-Megakaryocyte\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	CILP CD248 GAS1 SYDE1	1.46e-04	198	60	4	35edf6d5bedc2181fbdd56f43e458bc39f4eca16
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Hematopoietic-Megakaryocytic\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	CILP CD248 GAS1 SYDE1	1.46e-04	198	60	4	ff6d9455ebfe965cc6f48197172c0ebd3bddde81
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Hematopoietic\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	CILP CD248 GAS1 SYDE1	1.46e-04	198	60	4	5375a2895cf995f0db4a61861093f01794707901
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CRLF1 CILP CD248 GAS1	1.49e-04	199	60	4	1fd7bbb8727607e6507848602a19bc86882ef2d5
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ZNF469 CD248 GAS1 FGD1	1.49e-04	199	60	4	21335475bbfbad8a6943b8076a6c1c67f3eec5d3
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CRLF1 CILP CD248 GAS1	1.49e-04	199	60	4	9672230aa0bc6a7289050c955f5154ca183a5159
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CRLF1 CILP CD248 GAS1	1.49e-04	199	60	4	e18abe678da293bd01fae55e2f9ab6fdd643d02d
ToppCell	distal-3-mesenchymal-Adventitial_Fibroblast\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CILP CD248 GAS1 CDC42EP2	1.49e-04	199	60	4	547a7c30abc730af2670aee00c7a6af60426c9ac
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CRLF1 CILP CD248 GAS1	1.52e-04	200	60	4	17ffdbc13332bd3ed1d54abcd7af20267dd4b234
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Macroglial\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	GAS1 CDC42EP2 RPGR CD163	1.52e-04	200	60	4	ef222dc4a205d670172dae74990bdb952ac92e5b
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CILP CD248 GAS1 CDC42EP2	1.52e-04	200	60	4	a2bb67a06757f19be3f56f8cb5bb7e2affa5f4ed
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Macroglial-Astrocyte\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	GAS1 CDC42EP2 RPGR CD163	1.52e-04	200	60	4	98a994692440cb4f505b050276f0c8022c814a21
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CRLF1 CILP CD248 GAS1	1.52e-04	200	60	4	5c6520dc4c4693827f6680651785680b5883afb8
ToppCell	cellseq2-Mesenchymal-Fibroblastic\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CRLF1 CILP CD248 GAS1	1.52e-04	200	60	4	1c10597edd532bf172ca09870a937d35e2585081
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CRLF1 CILP CD248 GAS1	1.52e-04	200	60	4	665df8391d2ebcfc6536318612f4992852b5e2b8
ToppCell	cellseq2-Mesenchymal-Fibroblastic-Fibroblastic_1\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CRLF1 CILP CD248 GAS1	1.52e-04	200	60	4	440dda48b09c6a8581b7ca634b0d67f1ecacf65e
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CILP CD248 GAS1 CDC42EP2	1.52e-04	200	60	4	10f0c20ba7c71d9e2e177597f85b41cb40f0d878
ToppCell	cellseq2-Mesenchymal-Fibroblastic-Fibroblastic_1-AF2\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CRLF1 CILP CD248 GAS1	1.52e-04	200	60	4	44317fbf4d1480a37b50ab2777bf1a3e4fc0c05f
Drug	AZFd	RBMY1A1 RBMY1D RBMY1E F2	2.42e-07	23	54	4	CID000196489
Drug	PKI166	EGF RBMY1A1 RBMY1D RBMY1E	5.09e-06	48	54	4	CID006918403
Drug	hydantoin-5-propionic acid	RBMY1A1 RBMY1D RBMY1E	1.63e-05	21	54	3	CID000000782
Drug	4',5'-dimethylfluorescein	CRLF1 EGF	1.65e-05	3	54	2	CID003082937
Disease	polychlorinated biphenyls measurement, gestational serum measurement	FMN1 NCKAP5	1.91e-04	12	51	2	EFO_0007042, EFO_0007964
Disease	glomerulonephritis (is_marker_for)	F2 CD163	4.92e-04	19	51	2	DOID:2921 (is_marker_for)
Disease	CCL4 measurement	TBC1D3 TBC1D3F	5.46e-04	20	51	2	EFO_0004751
Disease	lymphocyte:monocyte ratio	ASXL1 MTF2 ICAM5 NLRP6	1.55e-03	288	51	4	EFO_0600088
Disease	macrophage inflammatory protein 1b measurement	TBC1D3 TBC1D3B TBC1D3F	1.70e-03	136	51	3	EFO_0008219

Protein segments in the cluster

Peptide	Gene	Start	Entry
DRALDTTAPRGPCIG	ENKD1	46	Q9H0I2
DPCRFALTSRGPEGG	ARHGEF25	426	Q86VW2
CTRPVDVRDSGGRPL	BBC3	231	Q96PG8
CRELGGDLATPRTPE	CD248	51	Q9HCU0
RDCLETGTPRPGGAS	BARHL1	56	Q9BZE3
CTGRSADLLLPPGDT	ANKS1A	866	Q92625
LSPGEILGCTSPRLS	DPH1	211	Q9BZG8
PLLPDSCETGTGLAR	ASXL1	1176	Q8IXJ9
SRGGTRELLPCGPET	ASXL2	736	Q76L83
PTLDLPCSIGRTEGT	MTF2	431	Q9Y483
GRVLPDPREACGSSS	RBMY1A1	461	P0DJD3
GRVLPDPREACGSSS	RBMY1C	461	P0DJD4
GRVLPDPREACGSSS	RBMY1D	461	P0C7P1
GRVLPDPREACGSSS	RBMY1E	461	A6NEQ0
DIRVPSSDGLSGPCR	R3HCC1	81	Q9Y3T6
CSSTEAGGDGIRRPP	FMN1	271	Q68DA7
TCPGDRSAITPGGLR	SHMT2	411	P34897
LLVCPGEGLSEPRSR	LY6G6F	181	Q5SQ64
LICTRESDPVRGPDG	SPINK5	786	Q9NQ38
ELTGTCSLLGPDLRP	ITGAE	121	P38570
STNCPRPERGGLETS	ICAM5	56	Q9UMF0
GPGPDLESLISRVCR	GDPGP1	261	Q6ZNW5
RAIEPCLPRTSGGGA	GAS1	141	P54826
LCVVDLSRGSTPLGP	FAAP100	366	Q0VG06
LDCGRPEPSARIVGG	PRSS36	36	Q5K4E3
TRTATVCGRELPDGP	CDC42EP2	86	O14613
SCGPRTRREPSSGEE	ELOA	6	Q14241
AGRLSEPGLICPDST	EGF	941	P01133
PGDPRLVISSGCATR	EXTL3	436	O43909
LRPGDESTPRGRCDS	CRACD	691	Q6ZU35
GVVSGGAEPCSRPRR	KLK9	216	Q9UKQ9
REPRLVGGDIPCSGR	CD163	476	Q86VB7
CEPRGGEPSSGPVRR	CRLF1	351	O75462
PCGELLERPGTRSLA	NLRP6	236	P59044
GGTRRASPPEFCVLG	PCARE	1246	A6NGG8
RTLPPIEGTLGLSAC	RPGR	426	Q92834
RVPPTTEGTRGLLSC	SYDE1	506	Q6ZW31
VAVLGEPGSDRRSCP	NCKAP5	1401	O14513
RGDTFCPGPTLSEDR	FGD1	921	P98174
PERPRTAGRTCEGTE	SHROOM2	826	Q13796
SCVSSGRPDRVPGGI	MYCBP2	781	O75592
RSSTPCPGGAVREDT	TBC1D3L	411	B9A6J9
DCRSPGLLDTTPIRG	SLX4	1466	Q8IY92
PAREDCRGLTGPLQS	ABCC8	651	Q09428
TDSDGRFRIPGLCPD	CILP	256	O75339
RSSTPCPGGAVREDT	TBC1D3B	411	A6NDS4
RSSTPCPGGAVREDT	TBC1D3H	411	P0C7X1
GPVRSAPCRTGTLEG	SHF	6	Q7M4L6
RTGSCEGFLPDPVLR	WDR90	346	Q96KV7
CTVTAPGLAGIPGRR	ZSWIM5	1081	Q9P217
GVTTCDPGTLRPADL	NEURL1	356	O76050
RSSTPCPGGAVREDT	TBC1D3F	411	A6NER0
EEFPGGLTIRCSPGR	XRN1	1146	Q8IZH2
RSSTPCPGGAVREDT	TBC1D3E	411	A0A087X179
PRVTCPSTGLGLGRT	ZNF469	2366	Q96JG9
PRTFGSGEADCGLRP	F2	326	P00734
RSSTPCPGGAVREDT	TBC1D3D	411	A0A087WVF3
RSSTPCPGGAVREDT	TBC1D3G	411	Q6DHY5
RSSTPCPGGAVREDT	TBC1D3	411	Q8IZP1
RSSTPCPGGAVREDT	TBC1D3K	411	A0A087X1G2
RSSTPCPGGAVREDT	TBC1D3I	411	A0A087WXS9
RSSTPCPGGAVREDT	TBC1D3C	411	Q6IPX1