Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
MousePheno	ocular hypertelorism	ROR2 TET1 CTNNB1 RREB1	1.18e-05	29	69	4	MP:0001300
Domain	RGS-like	ARHGEF1 ARHGEF12	6.56e-05	3	88	2	PF09128
Domain	RGS-like_dom	ARHGEF1 ARHGEF12	6.56e-05	3	88	2	IPR015212
Domain	HP	VILL AVIL	6.03e-04	8	88	2	PS51089
Domain	-	VILL AVIL	6.03e-04	8	88	2	1.10.950.10
Domain	Villin/Gelsolin	VILL AVIL	6.03e-04	8	88	2	IPR007122
Domain	VHP	VILL AVIL	6.03e-04	8	88	2	PF02209
Domain	Villin_headpiece	VILL AVIL	6.03e-04	8	88	2	IPR003128
Domain	GEL	VILL AVIL	6.03e-04	8	88	2	SM00262
Domain	VHP	VILL AVIL	6.03e-04	8	88	2	SM00153
Domain	LAM_G_DOMAIN	CELSR1 NRXN1 CSPG4	7.57e-04	38	88	3	PS50025
Domain	RGS	SNX25 ARHGEF1 ARHGEF12	8.17e-04	39	88	3	IPR016137
Domain	Laminin_G_2	CELSR1 NRXN1 CSPG4	8.80e-04	40	88	3	PF02210
Domain	LamG	CELSR1 NRXN1 CSPG4	1.16e-03	44	88	3	SM00282
Domain	Methyltransf_16	CAMKMT METTL22	1.17e-03	11	88	2	IPR019410
Domain	Methyltransf_16	CAMKMT METTL22	1.17e-03	11	88	2	PF10294
Domain	KRAB	ZNF311 ZNF776 ZNF559 ZNF587 ZNF317 ZNF417 ZNF124	1.51e-03	358	88	7	PS50805
Domain	KRAB	ZNF311 ZNF776 ZNF559 ZNF587 ZNF317 ZNF417 ZNF124	1.51e-03	358	88	7	PF01352
Domain	KRAB	ZNF311 ZNF776 ZNF559 ZNF587 ZNF317 ZNF417 ZNF124	1.79e-03	369	88	7	SM00349
Domain	KRAB	ZNF311 ZNF776 ZNF559 ZNF587 ZNF317 ZNF417 ZNF124	1.82e-03	370	88	7	IPR001909
Domain	Gelsolin	VILL AVIL	1.93e-03	14	88	2	PF00626
Domain	Gelsolin-like_dom	VILL AVIL	1.93e-03	14	88	2	IPR007123
Domain	Laminin_G	CELSR1 NRXN1 CSPG4	2.59e-03	58	88	3	IPR001791
Domain	ADF-H/Gelsolin-like_dom	VILL AVIL	5.66e-03	24	88	2	IPR029006
Domain	-	VILL AVIL	5.66e-03	24	88	2	3.40.20.10
Pathway	KEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNA12_13_RHO_SIGNALING_PATHWAY	ARHGEF1 ARHGEF12 CTNNB1	3.52e-05	13	72	3	M47547
Pubmed	PX-RICS, a novel splicing variant of RICS, is a main isoform expressed during neural development.	ARHGAP32 GRIN2B CTNNB1	1.56e-07	5	88	3	17663722
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	ARHGAP32 NRXN1 LRRC7 GRIN2B CTNNB1 FSCN1 DCTN1 ITIH4	2.57e-07	251	88	8	27507650
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	KIF21B ARHGAP32 DNAJC13 NRXN1 WDR81 ARHGEF12 LRRC7 GRIN2B CTNNB1 FSCN1 DCTN1 GOLGB1 ITIH4	9.15e-07	963	88	13	28671696
Pubmed	Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.	ABCC1 CELSR1 FAM13A ROR2 UGGT2 EIF2AK1	1.71e-06	142	88	6	19851296
Pubmed	Association of genetic variants with hemorrhagic stroke in Japanese individuals.	ABCC1 CELSR1 FAM13A ROR2 UGGT2 EIF2AK1	1.79e-06	143	88	6	20198315
Pubmed	RICS, a novel GTPase-activating protein for Cdc42 and Rac1, is involved in the beta-catenin-N-cadherin and N-methyl-D-aspartate receptor signaling.	ARHGAP32 GRIN2B CTNNB1	2.55e-06	11	88	3	12531901
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	ARHGAP32 UBXN4 RBM33 ROR2 LRRC7 TOR1AIP1 GOLGB1	4.92e-06	263	88	7	34702444
Pubmed	Polycystin-1 C-terminal tail associates with beta-catenin and inhibits canonical Wnt signaling.	PKD1 CTNNB1	6.33e-06	2	88	2	18632682
Pubmed	Homo- and hetero-oligomerization of PDZ-RhoGEF, LARG and p115RhoGEF by their C-terminal region regulates their in vivo Rho GEF activity and transforming potential.	ARHGEF1 ARHGEF12	6.33e-06	2	88	2	14712228
Pubmed	Predicting the effect of a point mutation on a protein fold: the villin and advillin headpieces and their Pro62Ala mutants.	VILL AVIL	6.33e-06	2	88	2	18022635
Pubmed	Glucocorticoid down-regulation of fascin protein expression is required for the steroid-induced formation of tight junctions and cell-cell interactions in rat mammary epithelial tumor cells.	CTNNB1 FSCN1	6.33e-06	2	88	2	10026156
Pubmed	MSSP, a protein binding to an origin of replication in the c-myc gene, interacts with a catalytic subunit of DNA polymerase alpha and stimulates its polymerase activity.	POLA1 RBMS1	6.33e-06	2	88	2	10869558
Pubmed	RAI3 knockdown promotes adipogenic differentiation of human adipose-derived stem cells by decreasing β-catenin levels.	CTNNB1 GPRC5A	6.33e-06	2	88	2	28870805
Pubmed	Stable genetic alterations of β-catenin and ROR2 regulate the Wnt pathway, affect the fate of MSCs.	ROR2 CTNNB1	6.33e-06	2	88	2	24590964
Pubmed	Positive cross talk between protein kinase D and β-catenin in intestinal epithelial cells: impact on β-catenin nuclear localization and phosphorylation at Ser552.	PKD1 CTNNB1	6.33e-06	2	88	2	26739494
Pubmed	Densin and beta-catenin form a complex and co-localize in cultured podocyte cell junctions.	LRRC7 CTNNB1	6.33e-06	2	88	2	17581699
Pubmed	Downregulation of TET1 Promotes Glioma Cell Proliferation and Invasion by Targeting Wnt/β-Catenin Pathway.	TET1 CTNNB1	6.33e-06	2	88	2	34926132
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF311 ZNF776 ZNF587 ZNF317 ZNF417 ZNF124	6.96e-06	181	88	6	37372979
Pubmed	Notum attenuates Wnt/β-catenin signaling to promote tracheal cartilage patterning.	ROR2 LRRC7 CTNNB1	1.24e-05	18	88	3	29428562
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	ARHGAP32 ARHGEF12 LRRC7 CTNNB1 GPRC5A FSCN1 PCDH1 IL6ST GOLGB1	1.35e-05	565	88	9	25468996
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	ARHGAP32 HSPA12A DNAJC13 ATP8A1 OXR1 MAP1B ARHGEF1 ARHGEF12 LRRC7 GRIN2B CTNNB1 FSCN1 DCTN1 PCDH1	1.39e-05	1431	88	14	37142655
Pubmed	Thrombin and lysophosphatidic acid receptors utilize distinct rhoGEFs in prostate cancer cells.	ARHGEF1 ARHGEF12	1.90e-05	3	88	2	15143072
Pubmed	Mechanistic insights into specificity, activity, and regulatory elements of the regulator of G-protein signaling (RGS)-containing Rho-specific guanine nucleotide exchange factors (GEFs) p115, PDZ-RhoGEF (PRG), and leukemia-associated RhoGEF (LARG).	ARHGEF1 ARHGEF12	1.90e-05	3	88	2	21454492
Pubmed	A hierarchy of ankyrin-spectrin complexes clusters sodium channels at nodes of Ranvier.	ANK1 AVIL	1.90e-05	3	88	2	25362473
Pubmed	Epigenetic identification of receptor tyrosine kinase-like orphan receptor 2 as a functional tumor suppressor inhibiting β-catenin and AKT signaling but frequently methylated in common carcinomas.	ROR2 CTNNB1	1.90e-05	3	88	2	24158497
Pubmed	Neurobeachin and the Kinesin KIF21B Are Critical for Endocytic Recycling of NMDA Receptors and Regulate Social Behavior.	KIF21B GRIN2B	1.90e-05	3	88	2	29847800
Pubmed	Update on the new classification of hepatic adenomas: clinical, molecular, and pathologic characteristics.	CTNNB1 IL6ST	1.90e-05	3	88	2	25076298
Pubmed	Wnt5a promotes hippocampal postsynaptic development and GluN2B-induced expression via the eIF2α HRI kinase.	GRIN2B EIF2AK1	1.90e-05	3	88	2	33795747
Pubmed	T-cell factor/β-catenin activity is suppressed in two different models of autosomal dominant polycystic kidney disease.	PKD1 CTNNB1	1.90e-05	3	88	2	21389971
Pubmed	B plexins activate Rho through PDZ-RhoGEF.	ARHGEF1 ARHGEF12	1.90e-05	3	88	2	12372594
Pubmed	Noncanonical Wnt5a enhances Wnt/β-catenin signaling during osteoblastogenesis.	ROR2 CTNNB1	1.90e-05	3	88	2	24670389
Pubmed	Functional proteomics mapping of a human signaling pathway.	CSRNP2 ZNF587 CSPG4 PKD1 GMEB1 CTNNB1 DCTN1 PCDH1 GOLGB1	1.93e-05	591	88	9	15231748
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	UBXN4 ATP8A1 RBM33 ZNF559 GNPTAB CSPG4 MCUR1 ZFAND6 SNCG RREB1 ZNF417 GOLGB1 ALG13	2.20e-05	1293	88	13	15342556
Pubmed	Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families.	DNAJC13 UBXN4 GPRC5A CHML TOR1AIP1 IL6ST GOLGB1	2.54e-05	339	88	7	37232246
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	KIF21B HSPA12A ATP8A1 ANK1 MAP1B LRRC7 GRIN2B CTNNB1 DCTN1	2.84e-05	621	88	9	22794259
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	HSPA12A ATP8A1 OXR1 MAP1B LRRC7 GRIN2B CTNNB1	2.94e-05	347	88	7	17114649
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	BPTF AARS2 ARHGEF1 UBA2 FSCN1 TOR1AIP1 GOLGB1	3.72e-05	360	88	7	33111431
Pubmed	ROR2 deficit may induce the tetralogy of Fallot via down-regulating of β-catenin/SOX3/HSPA6 in vitro and in vivo.	ROR2 CTNNB1	3.79e-05	4	88	2	37749917
Pubmed	Fascin, a novel target of beta-catenin-TCF signaling, is expressed at the invasive front of human colon cancer.	CTNNB1 FSCN1	3.79e-05	4	88	2	17638895
Pubmed	The splicing regulator PTBP2 controls a program of embryonic splicing required for neuronal maturation.	KIF21B ARHGEF12 GRIN2B	4.90e-05	28	88	3	24448406
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	ABCC1 CELSR1 MAP1B GNPTAB ROR2 CSPG4 LTN1 UGGT2 CTNNB1 GPRC5A TOR1AIP1 IL6ST	4.98e-05	1201	88	12	35696571
Pubmed	Neurotransmitter release regulated by a MALS-liprin-alpha presynaptic complex.	NRXN1 GRIN2B CTNNB1	6.05e-05	30	88	3	16186258
Pubmed	A novel mouse model reveals that polycystin-1 deficiency in ependyma and choroid plexus results in dysfunctional cilia and hydrocephalus.	PKD1 CTNNB1	6.30e-05	5	88	2	19774080
Pubmed	The AAA+ protein torsinA interacts with a conserved domain present in LAP1 and a novel ER protein.	LRRC7 TOR1AIP1	6.30e-05	5	88	2	15767459
Pubmed	Aquaporin-1 retards renal cyst development in polycystic kidney disease by inhibition of Wnt signaling.	PKD1 CTNNB1	6.30e-05	5	88	2	25573755
Pubmed	Polycystin: new aspects of structure, function, and regulation.	PKD1 CTNNB1	6.30e-05	5	88	2	11274246
Pubmed	p250GAP, a novel brain-enriched GTPase-activating protein for Rho family GTPases, is involved in the N-methyl-d-aspartate receptor signaling.	ARHGAP32 GRIN2B	6.30e-05	5	88	2	12857875
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	KIF21B ZZZ3 OXR1 ARHGEF1 TET1 UBA2 CAMKMT FRYL RFTN2 DCTN1 MYSM1 ALG13	6.86e-05	1242	88	12	30973865
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	HSPA12A DNAJC13 NRXN1 FRYL	7.26e-05	87	88	4	12465718
Pubmed	Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients.	ATP8A1 CAMKMT GRIN2B ITIH4	8.65e-05	91	88	4	22610502
Pubmed	Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.	FSIP2 HSPA12A UBXN4 FRYL CTNNB1 SNCG FSCN1 PCDH1	8.72e-05	558	88	8	35063084
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	THAP4 BPTF PPP2R3A DNAJC13 FAM13A MAP1B ZNF587 ROR2 CAMKMT LRRC7 FRYL PCDH1 GOLGB1	9.30e-05	1489	88	13	28611215
Pubmed	A role for spermine oxidase as a mediator of reactive oxygen species production in HIV-Tat-induced neuronal toxicity.	GRIN2B SMOX	9.43e-05	6	88	2	23665428
Pubmed	Multivalent interactions of calcium/calmodulin-dependent protein kinase II with the postsynaptic density proteins NR2B, densin-180, and alpha-actinin-2.	LRRC7 GRIN2B	9.43e-05	6	88	2	16120608
Pubmed	Novel roles of Pkd2 in male reproductive system development.	PKD1 CTNNB1	9.43e-05	6	88	2	24951251
Pubmed	Potent activation of RhoA by Galpha q and Gq-coupled receptors.	ARHGEF1 ARHGEF12	9.43e-05	6	88	2	12016230
Pubmed	Computer sequence analysis of human highly conserved zinc finger modules.	ZNF311 ZNF587	9.43e-05	6	88	2	10520746
Pubmed	Discrete somatic niches coordinate proliferation and migration of primordial germ cells via Wnt signaling.	ROR2 CTNNB1	9.43e-05	6	88	2	27402951
Pubmed	A bacterial effector targets host DH-PH domain RhoGEFs and antagonizes macrophage phagocytosis.	ARHGEF1 ARHGEF12	9.43e-05	6	88	2	20300064
Pubmed	Wnt signaling gradients establish planar cell polarity by inducing Vangl2 phosphorylation through Ror2.	ROR2 CTNNB1	9.43e-05	6	88	2	21316585
Pubmed	An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.	ARHGAP32 RBM33 ROR2 GPRC5A TOR1AIP1	9.72e-05	180	88	5	35198878
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	ABCC1 UBXN4 RBM33 ZFAND6 UGGT2 CTNNB1 ZNF317 RREB1 TOR1AIP1	1.01e-04	733	88	9	34672954
Pubmed	Alpha-E-catenin binds to dynamitin and regulates dynactin-mediated intracellular traffic.	CTNNB1 DCTN1	1.32e-04	7	88	2	19075109
Pubmed	PCP auto count: a novel Fiji/ImageJ plug-in for automated quantification of planar cell polarity and cell counting.	CELSR1 CTNNB1	1.32e-04	7	88	2	38827526
Pubmed	Crooked tail (Cd) model of human folate-responsive neural tube defects is mutated in Wnt coreceptor lipoprotein receptor-related protein 6.	CTNNB1 GPRC5A	1.32e-04	7	88	2	16126904
Pubmed	Pioglitazone improves the phenotype and molecular defects of a targeted Pkd1 mutant.	PKD1 CTNNB1	1.32e-04	7	88	2	12095915
Pubmed	Flattop regulates basal body docking and positioning in mono- and multiciliated cells.	CELSR1 CTNNB1	1.32e-04	7	88	2	25296022
Pubmed	Polycystin-1 binds Par3/aPKC and controls convergent extension during renal tubular morphogenesis.	PKD1 CTNNB1	1.32e-04	7	88	2	24153433
Pubmed	Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide polymorphisms.	IGF2BP2 RBMS1 ZFAND6	1.56e-04	41	88	3	20889853
Pubmed	ADAM10 hyperactivation acts on piccolo to deplete synaptic vesicle stores in Huntington's disease.	ATP8A1 OXR1 CTNNB1 FSCN1 DCTN1	1.67e-04	202	88	5	33601422
Pubmed	Defects in Synaptic Plasticity, Reduced NMDA-Receptor Transport, and Instability of Postsynaptic Density Proteins in Mice Lacking Microtubule-Associated Protein 1A.	MAP1B GRIN2B	1.75e-04	8	88	2	26609151
Pubmed	Diverse Targets of β-Catenin during the Epithelial-Mesenchymal Transition Define Cancer Stem Cells and Predict Disease Relapse.	ABCC1 CTNNB1	2.25e-04	9	88	2	26122848
Pubmed	The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling.	CTNNB1 CRBN	2.25e-04	9	88	2	34489457
Pubmed	Polycystic kidneys caused by sustained expression of Cux1 isoform p75.	PKD1 CTNNB1	2.25e-04	9	88	2	18356167
Pubmed	Frizzled3 and Frizzled6 Cooperate with Vangl2 to Direct Cochlear Innervation by Type II Spiral Ganglion Neurons.	CELSR1 ROR2	2.25e-04	9	88	2	31462532
Pubmed	A Novel Human CAMK2A Mutation Disrupts Dendritic Morphology and Synaptic Transmission, and Causes ASD-Related Behaviors.	LRRC7 GRIN2B	2.25e-04	9	88	2	28130356
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	IGF2BP2 AARS2 MAP1B LTN1 CTNNB1 GPRC5A FSCN1 DCTN1	2.39e-04	647	88	8	26618866
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	HSPA12A DNAJC13 PKD1 RBP4 ARHGEF12 GPRC5A SNCG RREB1 FIGNL1 ITIH4	2.49e-04	1016	88	10	19056867
Pubmed	Tbx1 regulates extracellular matrix-cell interactions in the second heart field.	CTNNB1 GOLGB1	2.81e-04	10	88	2	31180501
Pubmed	Modification of the composition of polycystin-1 multiprotein complexes by calcium and tyrosine phosphorylation.	PKD1 CTNNB1	2.81e-04	10	88	2	11113628
Pubmed	Pkd1 regulates lymphatic vascular morphogenesis during development.	PKD1 CTNNB1	2.81e-04	10	88	2	24767999
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	BPTF ARHGAP32 VILL RBM33 WDR81 FIGNL1	3.27e-04	363	88	6	14691545
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	FSIP2 ARHGAP32 FAM13A MAP1B ARHGEF1 ROR2 TET1 FRYL GOLGB1	3.34e-04	861	88	9	36931259
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	ARHGAP32 HSPA12A AARS2 NRXN1	3.41e-04	130	88	4	12421765
Pubmed	Ephrin-A5 and EphA5 interaction induces synaptogenesis during early hippocampal development.	CACNA1D GRIN2B	3.43e-04	11	88	2	20824214
Pubmed	A dual role for planar cell polarity genes in ciliated cells.	CELSR1 CTNNB1	3.43e-04	11	88	2	25024228
Pubmed	Wnt5a regulates directional cell migration and cell proliferation via Ror2-mediated noncanonical pathway in mammalian palate development.	ROR2 CTNNB1	3.43e-04	11	88	2	18948417
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	ARHGAP32 CSPG4 CTNNB1 PCDH1 TOR1AIP1 IL6ST	4.00e-04	377	88	6	38117590
Pubmed	A branching model of lineage differentiation underpinning the neurogenic potential of enteric glia.	IGF2BP2 CTNNB1	4.11e-04	12	88	2	37737269
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	IGF2BP2 AARS2 MAP1B POLA1 LTN1 UBA2 FSCN1 DCTN1	4.20e-04	704	88	8	29955894
Pubmed	SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.	BPTF HSPA12A MAP1B LTN1 TOR1AIP1	4.44e-04	250	88	5	33536335
Pubmed	A mutation in the tuft mouse disrupts TET1 activity and alters the expression of genes that are crucial for neural tube closure.	CELSR1 TET1	4.85e-04	13	88	2	26989192
Pubmed	Endothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells.	CSPG4 CTNNB1	5.65e-04	14	88	2	27516371
Pubmed	A critical role for miR-142 in alveolar epithelial lineage formation in mouse lung development.	CTNNB1 IL6ST	5.65e-04	14	88	2	30887098
Pubmed	Craniofacial abnormality with skeletal dysplasia in mice lacking chondroitin sulfate N-acetylgalactosaminyltransferase-1.	CSPG4 CTNNB1	5.65e-04	14	88	2	30459452
Pubmed	Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization.	HSPA12A MAP1B GRIN2B CTNNB1 FSCN1 DCTN1	5.68e-04	403	88	6	30562941
Pubmed	Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease.	CELSR1 ROR2 CTNNB1	5.83e-04	64	88	3	24431302
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	ABCC1 ARHGAP32 CSPG4 CTNNB1 GPRC5A PCDH1 IL6ST	6.12e-04	569	88	7	30639242
Pubmed	Tet proteins influence the balance between neuroectodermal and mesodermal fate choice by inhibiting Wnt signaling.	TET1 CTNNB1	6.51e-04	15	88	2	27930333
Pubmed	Parvins Are Required for Endothelial Cell-Cell Junctions and Cell Polarity During Embryonic Blood Vessel Formation.	CSPG4 CTNNB1	6.51e-04	15	88	2	29567677
GeneFamily	Gelsolin/villins	VILL AVIL	3.85e-04	8	68	2	950
Coexpression	ERWIN_COHEN_BLOOD_LIVE_VACCINE_TC_83_AGE_23_48YO_VACCINATED_VS_CONTROL_14DY_UP	UBXN4 ZZZ3 ATP8A1 OXR1 LTN1 UBA2 CHML FIGNL1 CRBN MYSM1 IL6ST ALG13	3.18e-06	687	88	12	M41022
Coexpression	ONKEN_UVEAL_MELANOMA_UP	ABCC1 CELSR1 DNAJC13 UBXN4 OXR1 POLA1 RBMS1 GNPTAB CSPG4 UGGT2 TOR1AIP1 ALG13	1.30e-05	790	88	12	M12490
Coexpression	RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP	MAGEA5P IGF2BP2 DNAJC13 UBXN4 OXR1 RBMS1 UGGT2 ZNF317 CHML RIOK2 FIGNL1	2.96e-05	721	88	11	M10237
Coexpression	GSE18281_PERIMEDULLARY_CORTICAL_REGION_VS_WHOLE_MEDULLA_THYMUS_UP	CACNA1D BPTF ARHGAP32 CELSR1 FSCN1 DCTN1	5.74e-05	199	88	6	M7259
Coexpression	HALLMARK_HEME_METABOLISM	ATG4A ANK1 ARHGEF12 PSMD9 EIF2AK1 SMOX	5.90e-05	200	88	6	M5945
Coexpression	GSE4535_BM_DERIVED_DC_VS_FOLLICULAR_DC_DN	NOD1 CSRNP2 RBMS1 ARHGEF1 TET1 GOLGB1	5.90e-05	200	88	6	M6574
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1D NRXN1 OXR1 MAP1B PKD1 LRRC7 GRIN2B	1.26e-07	196	88	7	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1D NRXN1 OXR1 MAP1B PKD1 LRRC7 GRIN2B	1.35e-07	198	88	7	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	10x5'v1-week_12-13-Myeloid_macrophage-stroma-osteoclast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PPP2R3A OXR1 GNPTAB ROR2 CSPG4 RFTN2	1.88e-06	186	88	6	c9dfcf7bba7e5ef97ad5d9b7084fba932c91ab68
ToppCell	10x5'v1-week_17-19-Myeloid_macrophage-stroma-osteoclast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PPP2R3A OXR1 GNPTAB ROR2 CSPG4 RFTN2	2.00e-06	188	88	6	762b52f21d2bc5409f86746a904c4358490be9c0
ToppCell	distal-3-Endothelial-Bronchial_Vessel_2\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ATG4A ZZZ3 ZNF559 ARHGEF12 PCDH1 ITIH4	2.70e-06	198	88	6	f701d06e3d7fd2192afae3698c5ec3c355e96da3
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1D NRXN1 OXR1 MAP1B LRRC7 GRIN2B	2.70e-06	198	88	6	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	CACNA1D OXR1 MAP1B PKD1 LRRC7 GRIN2B	2.86e-06	200	88	6	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN1 AVIL ROR2 CSPG4 SNCG	9.91e-06	144	88	5	121853910eeea1ea0642b3cc99f9200015480368
ToppCell	Endothelial-B-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	MAP1B RFTN2 GRIN2B SNCG FSCN1	1.97e-05	166	88	5	c286987ea4e511195607c87ec4529c2c2ed2122e
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	KIF21B NRXN1 MAP1B GRIN2B FSCN1	2.54e-05	175	88	5	9a96a946db731ba24c9be34bedebf1f4a1372b9e
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	KIF21B NRXN1 MAP1B GRIN2B FSCN1	2.54e-05	175	88	5	54c1f080195ad8392a095e83b56a4b54073d4c0d
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	KIF21B NRXN1 MAP1B GRIN2B FSCN1	2.54e-05	175	88	5	2b51406a2c2daa13ab4ed283ede038cd11d9e641
ToppCell	facs-Heart-LV-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP1B CSPG4 UBA2 SNCG ITIH4	2.83e-05	179	88	5	8da6863edc756540bb097cc7221c1408640d9bb4
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	IGF2BP2 ANK1 ARHGEF12 EIF2AK1 SMOX	2.83e-05	179	88	5	dfefa4b7ae0ee50cf67e0f1938c682f08a03ec53
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-hematologic-erythrocytic\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	IGF2BP2 ANK1 ARHGEF12 EIF2AK1 SMOX	2.83e-05	179	88	5	64672528f73ac0921f9c7df72e14ecbfac4d5270
ToppCell	facs-Heart-LV-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP1B CSPG4 UBA2 SNCG ITIH4	2.83e-05	179	88	5	f39c13c99a07d009cc677e363ffe089089c64916
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-hematologic\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	IGF2BP2 ANK1 ARHGEF12 EIF2AK1 SMOX	2.83e-05	179	88	5	fa0dd87111d399649cdea55f2e610ebc169e8a56
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	IGF2BP2 ANK1 ARHGEF12 EIF2AK1 SMOX	3.14e-05	183	88	5	b52d7683dc6652766e814ebe935c264ecd610c4b
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-hematologic\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	IGF2BP2 ANK1 ARHGEF12 EIF2AK1 SMOX	3.14e-05	183	88	5	1db466cf757813322db1cdcc0bf1d91c062fd9de
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-hematologic-erythrocytic\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	IGF2BP2 ANK1 ARHGEF12 EIF2AK1 SMOX	3.14e-05	183	88	5	1d77d8d8c8f78f43dd8864e76f294ee66d4942c2
ToppCell	COVID-19_Severe-RBC\|World / disease group, cell group and cell class	IGF2BP2 ANK1 ARHGEF12 EIF2AK1 SMOX	3.31e-05	185	88	5	96b7058b1b282134970aa9e75285760a9f94a8b5
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	IGF2BP2 ANK1 ARHGEF12 EIF2AK1 SMOX	3.57e-05	188	88	5	da211e7fb62fff176aa9c39061aef9ab0af6079e
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	ATP8A1 FAM13A CTNNB1 IL6ST GOLGB1	3.57e-05	188	88	5	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGAP32 CELSR1 ATP8A1 FAM13A GPRC5A	3.57e-05	188	88	5	4bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCell	Influenza_Severe-RBC\|World / Disease group and Cell class	IGF2BP2 ANK1 ARHGEF12 EIF2AK1 SMOX	3.57e-05	188	88	5	f0438e6a77ee1f0456cb65926685266fff470983
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-hematologic\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	IGF2BP2 ANK1 ARHGEF12 EIF2AK1 SMOX	3.57e-05	188	88	5	3c6c0eaadc474ebb218ae349b787c410f66177ab
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-hematologic-erythrocytic\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	IGF2BP2 ANK1 ARHGEF12 EIF2AK1 SMOX	3.57e-05	188	88	5	3467149de45b47a5015486ef94bec070e9c3ffc2
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BPTF MAP1B ARHGEF12 CTNNB1 GOLGB1	3.76e-05	190	88	5	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	10x5'v1-week_12-13-Myeloid_macrophage\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PPP2R3A OXR1 GNPTAB CSPG4 RFTN2	3.85e-05	191	88	5	be2fe2583bdcee0b35c43a347da9c4adb93e30e0
ToppCell	10x5'v1-week_12-13-Myeloid_macrophage-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PPP2R3A OXR1 GNPTAB CSPG4 RFTN2	3.85e-05	191	88	5	4cebaf31d4f09f4ab273a819ad5cbff7d9a9b341
ToppCell	PBMC-Severe-Hematopoietic\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGF2BP2 ANK1 ARHGEF12 EIF2AK1 SMOX	3.95e-05	192	88	5	68d0bf6249a24d23cb1b0be434bced2ff2d0f2b4
ToppCell	droplet-Lung-3m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CELSR1 ATP8A1 SNX25 GPRC5A ITIH4	3.95e-05	192	88	5	13e4b17d7a592604140777aca235f795df6b3f91
ToppCell	PBMC-Severe-Hematopoietic\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	IGF2BP2 ANK1 ARHGEF12 EIF2AK1 SMOX	3.95e-05	192	88	5	3b75fe82018bb259b02bfaee96b310f4d6df0350
ToppCell	droplet-Lung-3m-Epithelial-alveolar_epithelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CELSR1 ATP8A1 SNX25 GPRC5A ITIH4	3.95e-05	192	88	5	f51b3fd962263920a6cae783ca7af13f5eb7aaa3
ToppCell	Influenza_Severe-RBC\|Influenza_Severe / Disease group and Cell class	IGF2BP2 ANK1 ARHGEF12 EIF2AK1 SMOX	3.95e-05	192	88	5	f19b6da3fd98da1a76d2570137a8f73a3850ebcb
ToppCell	droplet-Lung-3m-Epithelial-alveolar_epithelial-type_II_pneumocyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CELSR1 ATP8A1 SNX25 GPRC5A ITIH4	3.95e-05	192	88	5	6244541688f85917018a057aa0b3e5972934dfbc
ToppCell	10x_3'_v3-bone_marrow_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte\|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ATG4A ANK1 ARHGEF12 EIF2AK1 SMOX	4.05e-05	193	88	5	305e15ee467826ee08b2617c69f250ad39c11b19
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP1B CSPG4 UBA2 SNCG ITIH4	4.05e-05	193	88	5	0266a4fdf436d83ec1d9392abba8c6ec5166970a
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	BPTF IGF2BP2 RBM33 RBMS1 GOLGB1	4.05e-05	193	88	5	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	severe_influenza-RBC\|severe_influenza / disease group, cell group and cell class (v2)	IGF2BP2 ANK1 ARHGEF12 EIF2AK1 SMOX	4.05e-05	193	88	5	ffb0b3c2cce13b6891157f0fede2600f3938670e
ToppCell	10x_3'_v3-bone_marrow_(10x_3'_v3)-hematologic-erythrocytic\|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ATG4A ANK1 ARHGEF12 EIF2AK1 SMOX	4.05e-05	193	88	5	dd376664906caccc9c2065f8e7a364509e18a5cc
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1D NRXN1 MAP1B FRYL GOLGB1	4.25e-05	195	88	5	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1D NRXN1 MAP1B FRYL GOLGB1	4.25e-05	195	88	5	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	367C-Fibroblasts-Fibroblast-K_(Pericytes)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	CSPG4 UBA2 SNCG PCDH1 ITIH4	4.36e-05	196	88	5	1d94cecd378a829dd8014fc086d7fca48c953a91
ToppCell	367C-Fibroblasts-Fibroblast-K_(Pericytes)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	CSPG4 UBA2 SNCG PCDH1 ITIH4	4.36e-05	196	88	5	aacec48285bcb7ccf1b538187071885e3602cc49
ToppCell	distal-Endothelial-Bronchial_Vessel_2-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ATG4A ZZZ3 ZNF559 ARHGEF12 ITIH4	4.46e-05	197	88	5	9fcfbfbe78e8fe90c76eb37a58ed9dc8ece652a1
ToppCell	COVID-19-COVID-19_Mild-Others-RBC\|COVID-19_Mild / Disease, condition lineage and cell class	IGF2BP2 ANK1 ARHGEF12 EIF2AK1 SMOX	4.46e-05	197	88	5	3bae601e5d9689ea57e923814af8cdcae690becc
ToppCell	10x3'2.3-week_12-13-Myeloid_macrophage-stroma-osteoclast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PPP2R3A OXR1 GNPTAB ROR2 RFTN2	4.46e-05	197	88	5	1bf69db7e830315c8fa85e6e85b0cb94014e9169
ToppCell	ILEUM-inflamed-(8)_Fibroblast-(8)_Pericytes\|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	MAP1B CSPG4 UBA2 SNCG PCDH1	4.57e-05	198	88	5	5e274c5597d8720290d452465f0bd40637cb3f27
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARHGAP32 NRXN1 OXR1 MAP1B GRIN2B	4.57e-05	198	88	5	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1D NRXN1 OXR1 MAP1B GRIN2B	4.57e-05	198	88	5	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1D OXR1 MAP1B LRRC7 GRIN2B	4.57e-05	198	88	5	0ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn-35\|World / Primary Cells by Cluster	BPTF FAM13A NRXN1 MAP1B LRRC7	4.57e-05	198	88	5	de5214a85fe017eb23d4aa8af624464f062ec57e
ToppCell	Bronchial-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 CELSR1 ATP8A1 SNX25 GPRC5A	4.68e-05	199	88	5	5f7da3eab58ace6cddb3179a415cd839d5767958
ToppCell	Parenchymal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 CELSR1 ATP8A1 SNX25 GPRC5A	4.68e-05	199	88	5	5cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCell	Influenza-Influenza_Severe-Others-RBC\|Influenza_Severe / Disease, condition lineage and cell class	IGF2BP2 ANK1 ARHGEF12 EIF2AK1 SMOX	4.68e-05	199	88	5	da0fec0a492bc3827d9066d2590bcd466cd45564
ToppCell	Influenza-Influenza_Severe-Others\|Influenza_Severe / Disease, condition lineage and cell class	IGF2BP2 ANK1 ARHGEF12 EIF2AK1 SMOX	4.79e-05	200	88	5	8909da4f7da3bc469a2becb4cfa5c25012af5845
ToppCell	COVID-19-COVID-19_Severe-Others-RBC\|COVID-19_Severe / Disease, condition lineage and cell class	IGF2BP2 ANK1 ARHGEF12 EIF2AK1 SMOX	4.79e-05	200	88	5	308f74e7e13ecc6d133c219c42cc8895a96644c8
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	CELSR1 ATP8A1 CATSPER4 ARHGEF1 GOLGB1	4.79e-05	200	88	5	8683445ad5b70748c4a1f12eb77d47623085147e
ToppCell	COVID-19-COVID-19_Severe-Others\|COVID-19_Severe / Disease, condition lineage and cell class	IGF2BP2 ANK1 ARHGEF12 EIF2AK1 SMOX	4.79e-05	200	88	5	932b310a2838e4b354b90460fa904a8ebca4747a
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Neuronal\|6m / Sample Type, Dataset, Time_group, and Cell type.	KIF21B NRXN1 MAP1B LRRC7 GRIN2B	4.79e-05	200	88	5	cedbc47b1defb5973cf7ab6baaa2d6f2fd481f88
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Cortical_neuron\|6m / Sample Type, Dataset, Time_group, and Cell type.	KIF21B NRXN1 MAP1B LRRC7 GRIN2B	4.79e-05	200	88	5	6f7ff0533339fcc9d316f2c77334a79c1409ec4f
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ROR2 GRIN2B GPRC5A IQUB	2.06e-04	147	88	4	64fa0753a3a79f492ef8acc6942bf90d379a983f
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_TIP\|Cerebellum / BrainAtlas - Mouse McCarroll V32	ROR2 RBP4 GPRC5A ITIH4	2.17e-04	149	88	4	3980fa4f1986a2f164a1826ea043fb71f1d756cd
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-lymphoid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LDHD PPP2R3A MAP1B CATSPER4	2.34e-04	152	88	4	acfafdb64bd5b0eb7371b04cfef51ed2798e9b30
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-common_lymphoid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LDHD PPP2R3A MAP1B CATSPER4	2.34e-04	152	88	4	9d6c88ceca0569dbeb12e488acec7fcb7f972f03
ToppCell	PND14-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANK1 POLA1 FIGNL1 ALG13	2.59e-04	156	88	4	8349604bd801e20d33770f7d8243598c3756302b
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZNF776 ARHGEF1 LRRC7 ZNF417	2.85e-04	160	88	4	1a9329d8183296f36928bd9e96f10db9f04ce326
ToppCell	facs-Marrow-Granulocytes-18m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LDHD ANK1 ARHGEF12 ITIH4	2.92e-04	161	88	4	60f433eab9d5531bdf6aa86b0265f20b866b904c
ToppCell	TCGA-Uterus-Primary_Tumor-Uterine_Carcinoma-Uterine_Carcinosarcoma-3\|TCGA-Uterus / Sample_Type by Project: Shred V9	GNPTAB RBP4 FRYL PCDH1	3.06e-04	163	88	4	d64dd39b077105c73e570ccef70f0e74a2c586ac
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-ventral_progenitors_and_neurons_1\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	KIF21B NRXN1 GRIN2B PDCL2	3.20e-04	165	88	4	9795ce31689bc63f5a2d68725ef00b23a90c3846
ToppCell	Endothelial-B-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	MAP1B GRIN2B SNCG FSCN1	3.20e-04	165	88	4	b6893882472aeb0d18e26f47eaec9d53688afcde
ToppCell	Ionocyte\|World / Class top	CACNA1D NRXN1 CSPG4 CAMKMT	3.58e-04	170	88	4	d2e592f2a679e6a8d32f2b752d9a3c493e50ced4
ToppCell	PND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATP8A1 POLA1 SNX25 CTNNB1	3.58e-04	170	88	4	4ce81608111b9ee7cb974dad2c182f38db3dcd79
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGAP32 HSPA12A NRXN1 CSPG4	3.58e-04	170	88	4	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	Endothelial-B-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	MAP1B GRIN2B SNCG FSCN1	3.75e-04	172	88	4	8a527dff06d841a86c7eb04a1dd9630787294da4
ToppCell	PND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CELSR1 IGF2BP2 ATP8A1 GPRC5A	3.83e-04	173	88	4	45808cf69122c16b9d2b5ffa06d15392c55954b7
ToppCell	droplet-Spleen-SPLEEN-30m-Hematologic-erythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATG4A ANK1 EIF2AK1 SMOX	3.83e-04	173	88	4	a8fb8db6061fa4d8d56a7b45004ecbd344501573
ToppCell	PND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CELSR1 IGF2BP2 ATP8A1 GPRC5A	3.83e-04	173	88	4	7fa9dbcb258c3ab974490063951620e2def03db1
ToppCell	droplet-Heart-HEART-1m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR1 IGF2BP2 WDR81 RFTN2	3.83e-04	173	88	4	9dc7746a84f0e268a7c061e1bbcd5e31903034dc
ToppCell	tumor_Lung-Myeloid_cells-Undetermined\|Myeloid_cells / Location, Cell class and cell subclass	NRXN1 MAP1B CSPG4 RFTN2	3.83e-04	173	88	4	934550c0290fb1058f353d97dba92757aeb2075e
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1D NRXN1 FRYL PDCL2	3.91e-04	174	88	4	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-5\|TCGA-Pancreas / Sample_Type by Project: Shred V9	CELSR1 IGF2BP2 SNCG FSCN1	3.91e-04	174	88	4	73e1ad4007d94fca25ed7c6fbe5d205d4e1b8a3b
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 ZFAND6 EIF2AK1 SMOX	3.91e-04	174	88	4	81ab196e36cac2a7974d6e3fe457efffddfd03bb
ToppCell	NS-moderate-d_07-13-Lymphoid-NK\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MAP1B CSPG4 TET1 RFTN2	4.00e-04	175	88	4	f6cd24d22f62469319f9d244e3e5de527d3d4d94
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Epithelial-mature_enterocytic-Enterocyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1D CELSR1 RBP4 CCL15	4.08e-04	176	88	4	24eedbbb406d788630bb16678cceef4492d3999c
ToppCell	droplet-Marrow-nan-24m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATG4A ANK1 AVIL SMOX	4.08e-04	176	88	4	fc51e4dcad5456c229d76fdcb9a80c4c79eacf3f
ToppCell	droplet-Marrow-nan-24m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATG4A ANK1 EIF2AK1 SMOX	4.08e-04	176	88	4	f92063b72ebfeb9b192281dc63d6bf2759c78554
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	CACNA1D MAP1B RFTN2 IGDCC4	4.17e-04	177	88	4	cdfd2f0ee2f692271b1525e414b0f645cdadb1f6
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAP1B CSPG4 RBP4 UGGT2	4.17e-04	177	88	4	6b4fe717928814dafcd13090b1c90ea973938c6d
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|356C / Donor, Lineage, Cell class and subclass (all cells)	CACNA1D MAP1B RFTN2 IGDCC4	4.17e-04	177	88	4	db222faaecbe5600da39277243c4e7e764eb63c9
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_naive-11\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CACNA1D SNX25 ZNF587 LRRC7	4.17e-04	177	88	4	3535575686c9700ab72700aae6f2070ebbb50044
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP32 HSPA12A MAP1B IL6ST	4.35e-04	179	88	4	025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ARHGAP32 ZNF587 GPRC5A GOLGB1	4.35e-04	179	88	4	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	CSPG4 RBP4 SNCG IGDCC4	4.35e-04	179	88	4	98c0c5c8034ae8a4b3ceea7fd1d0386ee5f89d09
ToppCell	COVID-19_Moderate-RBC\|World / disease group, cell group and cell class	IGF2BP2 ANK1 EIF2AK1 SMOX	4.35e-04	179	88	4	932fa98c0981ef8ef1e4945cdd4ae8c6c0858251
ToppCell	ASK454-Endothelial-Lymphatic\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	HSPA12A SNCG FSCN1 CHML	4.35e-04	179	88	4	fd84a79f76a01c0377dff5b20016b004d369f96f
ToppCell	human_hepatoblastoma-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	ABCC1 ATP8A1 OXR1 GRIN2B	4.35e-04	179	88	4	14fc8ccb6b215063d747643f47d780d2b237eb67
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D ROR2 LRRC7 IGDCC4	4.45e-04	180	88	4	08ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell	facs-Heart-RV-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSPG4 UBA2 SNCG ITIH4	4.45e-04	180	88	4	0059e5acade6c895fd629767bea1c15f40b0d1b0
Disease	Abnormality of refraction	CACNA1D ARHGAP32 DNAJC13 NOD1 FAM13A RBMS1 CAMKMT GRIN2B CTNNB1 DCTN1 TOR1AIP1	2.92e-06	673	83	11	HP_0000539
Disease	reticulocyte count	NOD1 ANK1 OXR1 RBMS1 PKD1 LTN1 PCDHGB4 ZFAND6 EIF2AK1 RREB1 SMOX	1.64e-04	1045	83	11	EFO_0007986
Disease	neuroimaging measurement	KIF21B CELSR1 CSRNP2 MAP1B ARHGEF1 ROR2 PKD1 ARHGEF12 FRYL PDCL2 RREB1	1.99e-04	1069	83	11	EFO_0004346
Disease	autosomal dominant nonsyndromic deafness (is_implicated_in)	THOC1 MAP1B	4.23e-04	11	83	2	DOID:0050564 (is_implicated_in)
Disease	vascular dementia (is_marker_for)	GRIN2B SNCG	4.23e-04	11	83	2	DOID:8725 (is_marker_for)
Disease	response to vaccine, cytokine measurement	ATP8A1 CAMKMT GRIN2B ITIH4	5.20e-04	131	83	4	EFO_0004645, EFO_0004873
Disease	reticulocyte measurement	NOD1 ANK1 OXR1 RBMS1 LTN1 PCDHGB4 ZFAND6 EIF2AK1 RREB1 SMOX	7.38e-04	1053	83	10	EFO_0010700
Disease	age at first sexual intercourse measurement	CACNA1D BPTF NRXN1 RBMS1 CAMKMT CRBN	7.49e-04	383	83	6	EFO_0009749
Disease	Alzheimer's disease (is_marker_for)	BPTF GRIN2B CTNNB1 SNCG IL6ST	8.05e-04	257	83	5	DOID:10652 (is_marker_for)
Disease	diabetes mellitus	IGF2BP2 ANK1 RREB1	9.43e-04	68	83	3	EFO_0000400
Disease	Multiple congenital anomalies	NRXN1 CTNNB1	1.03e-03	17	83	2	C0000772
Disease	Cannabis use, age at onset	PCDHGB4 LRRC7	1.30e-03	19	83	2	EFO_0004847, EFO_0007585
Disease	susceptibility to scarlet fever measurement	PPP2R3A CELSR1 FRYL	1.45e-03	79	83	3	EFO_0008409
Disease	gestational age, birth measurement	PPP2R3A OXR1	1.59e-03	21	83	2	EFO_0005112, EFO_0006921
Disease	Intellectual Disability	BPTF NRXN1 OXR1 MAP1B GRIN2B ALG13	1.65e-03	447	83	6	C3714756
Disease	Autism Spectrum Disorders	NRXN1 TET1 GRIN2B	1.80e-03	85	83	3	C1510586
Disease	colorectal cancer, hormone replacement therapy	IGF2BP2 RBP4 GRIN2B	1.98e-03	88	83	3	EFO_0003961, MONDO_0005575
Disease	carnosine measurement	OXR1 SMOX	2.07e-03	24	83	2	EFO_0010470
Disease	Neurodevelopmental Disorders	GRIN2B CTNNB1 ALG13	2.32e-03	93	83	3	C1535926

Protein segments in the cluster

Peptide	Gene	Start	Entry
FENELETNSEEQNSQ	ARHGEF1	31	Q92888
FVDTEENGTVNDQTF	ATG4A	286	Q8WYN0
GQFVVTEITDFTQDD	AVIL	626	O75366
EVGNENNSVTVFIEE	ALG13	516	Q9NP73
QQQRITFSETGAEEE	CATSPER4	321	Q7RTX7
QDSTGEALVNFTQAE	CSPG4	1636	Q6UVK1
QSQIQVFEDGADTTS	DCTN1	91	Q14203
QGSETQDFQEFIAEN	CSRNP2	306	Q9H175
TEEQFTDEQGNIVTK	ANK1	1811	P16157
SNVQEREAQFGTTAE	CRBN	126	Q96SW2
VLGSQAQFTNDAETE	CCL15	16	Q16663
DVFVFNVQNDTDVSS	CELSR1	1241	Q9NYQ6
CQESSQVDVVNVSEG	BPTF	1156	Q12830
AFSQDENGIVSQSEV	ATP8A1	1136	Q9Y2Q0
VAFGESQSEDEQFEN	ARHGEF12	746	Q9NZN5
EDQIFSTEVRGNETQ	IGDCC4	571	Q8TDY8
QNITFQTESSVAEQE	ITIH4	516	Q14624
QTESSVAEQEAEFQS	ITIH4	521	Q14624
EYQQNNDIGEESTVV	CHML	61	P26374
SQEEITQGFEETGDT	GPRC5A	301	Q8NFJ5
NEDEENFSSQGVTIS	RBM33	76	Q96EV2
EEASGQQQVAVETSN	RBMS1	381	P29558
DGQFDQEDGVTQVTC	RFTN2	486	Q52LD8
ATDQDEGVNAEITFS	PCDHGB4	266	Q9UN71
VQFAQEIDQVSSSAD	KIAA1107	856	Q9UPP5
VTGENKDVSETSFQN	LTN1	1326	O94822
SQSFTQEQVADIDGQ	CTNNB1	71	P35222
EEIEQIVQQSDAFSG	FIGNL1	591	Q6PIW4
FNVGTDDIAIEESNA	NRXN1	156	P58400
ETNNEETESPSQEFV	MAP1B	1146	P46821
EDNGFATQQAEIIVS	MCUR1	176	Q96AQ8
VGVQAATTEEQEAVS	MAGEA5P	26	P43359
SQVFDEVDTDQSGVL	GNPTAB	1011	Q3T906
EAGSENNTAVVAVET	GMEB1	56	Q9Y692
NTGFVAEETTAENAN	LRRC7	776	Q96NW7
SEFQPQVEEEVSNSE	FSIP2	6296	Q5CZC0
SGNQYVNEVTNAEED	PDCL2	96	Q8N4E4
VSQVAAEDFDSGVNA	PCDH1	736	Q08174
VVFSSNEDLEVGDQQ	FRYL	2381	O94915
VAVEDNSSEQQFGVF	FRYL	2411	O94915
NVQQENGYASTDEEI	KIF21B	1096	O75037
FVFTQEEVQASGLQE	NOD1	476	Q9Y239
IVNDTDSNVSEQQSF	HSPA12A	41	O43301
GTVENVEQVNTDTET	IGF2BP2	106	Q9Y6M1
FNVGTDDIAIEESNA	NRXN1	1191	Q9ULB1
TNETVAQEAYESEVQ	ARHGAP32	961	A7KAX9
NQDAGDQEESFVSEV	FAM13A	546	O94988
TLVAEESAQAQFQEG	PPP2R3A	1096	Q06190
QEGDSSFSVQEVQVD	POLA1	311	P09884
VIFSTNEVVDAENTQ	LRIT1	511	Q9P2V4
ASSESVQTVNQAEVE	OXR1	366	Q8N573
GNFTDVSVVEIEAND	IL6ST	686	P40189
LSANQDEETDQETFQ	FSCN1	281	Q16658
SSEENVNFLGQTEAQ	EIF2AK1	361	Q9BQI3
RTEEIVQQNGASDFS	LDHD	341	Q86WU2
GDVVASNAELESQFQ	DNAJC13	416	O75165
QNIVNSTEESDDAFD	IQUB	11	Q8NA54
TESVNTENVSGEGEN	CACNA1D	471	Q01668
VTAENEVGSAQDSIF	PKD1	1611	P98161
STEQEQDAEENGVTG	ABCC1	871	P33527
DDEIVEFGSVNTQNF	PSMD9	156	O00233
EQANAVSEAVVSSVN	SNCG	61	O76070
DDGTNQINEQASFAV	SNX25	431	Q9H3E2
EVQSQGEETNASDQQ	UBA2	286	Q9UBT2
QSTVQEAEEEEEGSV	ROR2	906	Q01974
QAGTDTTGQEVAEAQ	METTL22	101	Q9BUU2
ENTVQEAVGQDEAVY	AARS2	681	Q5JTZ9
QEAFEATANQQEVSD	TET1	346	Q8NFU7
NVEDVLTSFDNTGNV	CAMKMT	111	Q7Z624
TSVQQKVNFSEEGET	TOR1AIP1	206	Q5JTV8
FLQTAEDNTQDEVAG	RREB1	1196	Q92766
QDNIVAEFSVDETGQ	RBP4	56	P02753
ETEDVQASVSDTAQQ	ZFAND6	116	Q6FIF0
QQGTVTFEDVAVNFS	ZNF587	11	Q96SQ5
NAESQNSVGVFTREE	SMOX	161	Q9NWM0
QQGTVTFEDVAVNFS	ZNF417	11	Q8TAU3
QVVENNSVTEFSEEK	RIOK2	406	Q9BVS4
TNVEVVNDGAESAAF	VILL	326	O15195
NSVAFEDVAVNFTQE	ZNF124	11	Q15973
NTTVEDETETNEVQG	UGGT2	256	Q9NYU1
VFVVFVAGDDEQSTQ	UBXN4	21	Q92575
QDSVTFEDVAVDFTQ	ZNF559	11	Q9BR84
QRSTVVDNDADFQGT	ZZZ3	146	Q8IYH5
VGSQESVTFQDVAVD	ZNF317	51	Q96PQ6
AFVSAQNTGVVEVEE	THAP4	496	Q8WY91
QTIQETTGREDFTEN	WDR81	611	Q562E7
VTVFNTNEQESTLGQ	THOC1	186	Q96FV9
QESVTFEDVAVNFTN	ZNF311	61	Q5JNZ3
QGTVTFEDVAVNFSQ	ZNF776	11	Q68DI1
DVYNEGTQAVTEENI	GOLGB1	456	Q14789
ETNQGEFITSDSQEA	MYSM1	256	Q5VVJ2
GVVFADDTDQEAIAQ	GRIN2B	96	Q13224