Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	alpha-1,4-glucosidase activity	MGAM GAA	5.87e-05	5	49	2	GO:0004558
GeneOntologyMolecularFunction	alpha-glucosidase activity	MGAM GAA	1.23e-04	7	49	2	GO:0090599
GeneOntologyMolecularFunction	protein serine kinase activity	RAF1 LIMK1 LIMK2 BUB1 LRRK2 MAP2K5	2.50e-04	363	49	6	GO:0106310
GeneOntologyMolecularFunction	nuclear receptor coactivator activity	TRERF1 ACTN2 PPARG	4.52e-04	61	49	3	GO:0030374
GeneOntologyMolecularFunction	glucosidase activity	MGAM GAA	6.07e-04	15	49	2	GO:0015926
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	RAF1 LIMK1 LIMK2 BUB1 LRRK2 MAP2K5	7.45e-04	446	49	6	GO:0004674
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	RAF1 LIMK1 LIMK2 N4BP2 BUB1 LRRK2 MAP2K5	1.62e-03	709	49	7	GO:0016773
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	RAF1 LIMK1 LIMK2 N4BP2 BUB1 LRRK2 TUT1 MAP2K5	1.87e-03	938	49	8	GO:0016772
GeneOntologyMolecularFunction	MAP kinase kinase kinase activity	RAF1 LRRK2	1.99e-03	27	49	2	GO:0004709
GeneOntologyMolecularFunction	kinase activity	RAF1 LIMK1 LIMK2 N4BP2 BUB1 LRRK2 MAP2K5	2.47e-03	764	49	7	GO:0016301
GeneOntologyMolecularFunction	lipid binding	FFAR3 GPR42 PACSIN3 PLEKHA2 PNPLA3 ACTN2 PPARG PACSIN2	2.59e-03	988	49	8	GO:0008289
GeneOntologyBiologicalProcess	maltose metabolic process	MGAM GAA	1.59e-05	3	48	2	GO:0000023
GeneOntologyBiologicalProcess	positive regulation of acute inflammatory response to non-antigenic stimulus	FFAR3 GPR42	1.59e-05	3	48	2	GO:0002879
GeneOntologyBiologicalProcess	regulation of acute inflammatory response to non-antigenic stimulus	FFAR3 GPR42	3.17e-05	4	48	2	GO:0002877
GeneOntologyBiologicalProcess	acute inflammatory response to non-antigenic stimulus	FFAR3 GPR42	5.28e-05	5	48	2	GO:0002525
GeneOntologyBiologicalProcess	positive regulation of neuronal action potential	FFAR3 GPR42	7.91e-05	6	48	2	GO:1904457
GeneOntologyCellularComponent	CHD-type complex	CHD5 CHD3	7.45e-04	17	50	2	GO:0090545
GeneOntologyCellularComponent	NuRD complex	CHD5 CHD3	7.45e-04	17	50	2	GO:0016581
GeneOntologyCellularComponent	pseudopodium	RAF1 ACTN2	8.37e-04	18	50	2	GO:0031143
GeneOntologyCellularComponent	autolysosome	LRRK2 GAA	8.37e-04	18	50	2	GO:0044754
GeneOntologyCellularComponent	histone deacetylase complex	TRERF1 CHD5 CHD3	1.11e-03	85	50	3	GO:0000118
MousePheno	abnormal sympathetic neuron innervation pattern	FFAR3 GPR42	2.15e-05	3	38	2	MP:0009284
MousePheno	abnormal sympathetic neuron physiology	FFAR3 GPR42	4.30e-05	4	38	2	MP:0009253
Domain	CHDCT2	CHD5 CHD3	2.02e-05	3	49	2	PF08074
Domain	CHDNT	CHD5 CHD3	2.02e-05	3	49	2	PF08073
Domain	DUF1086	CHD5 CHD3	2.02e-05	3	49	2	IPR009462
Domain	DUF1087	CHD5 CHD3	2.02e-05	3	49	2	IPR009463
Domain	CHD_N	CHD5 CHD3	2.02e-05	3	49	2	IPR012958
Domain	CHD_C2	CHD5 CHD3	2.02e-05	3	49	2	IPR012957
Domain	DUF1087	CHD5 CHD3	2.02e-05	3	49	2	PF06465
Domain	DUF1086	CHD5 CHD3	2.02e-05	3	49	2	PF06461
Domain	DUF1087	CHD5 CHD3	2.02e-05	3	49	2	SM01147
Domain	DUF1086	CHD5 CHD3	2.02e-05	3	49	2	SM01146
Domain	GPR40-rel_orph	FFAR3 GPR42	4.03e-05	4	49	2	IPR013312
Domain	Glyco_hydro_31_CS	MGAM GAA	4.03e-05	4	49	2	IPR030459
Domain	NtCtMGAM_N	MGAM GAA	4.03e-05	4	49	2	PF16863
Domain	Gal_mutarotase_N	MGAM GAA	4.03e-05	4	49	2	IPR031727
Domain	GLYCOSYL_HYDROL_F31_2	MGAM GAA	6.71e-05	5	49	2	PS00707
Domain	Glyco_hydro_31_AS	MGAM GAA	1.00e-04	6	49	2	IPR030458
Domain	Glyco_hydro_31	MGAM GAA	1.40e-04	7	49	2	IPR000322
Domain	Glyco_hydro_31	MGAM GAA	1.40e-04	7	49	2	PF01055
Domain	GLYCOSYL_HYDROL_F31_1	MGAM GAA	1.40e-04	7	49	2	PS00129
Domain	Trefoil	MGAM GAA	1.87e-04	8	49	2	PF00088
Domain	P_TREFOIL_1	MGAM GAA	1.87e-04	8	49	2	PS00025
Domain	P_trefoil_CS	MGAM GAA	1.87e-04	8	49	2	IPR017957
Domain	P_TREFOIL_2	MGAM GAA	2.40e-04	9	49	2	PS51448
Domain	PD	MGAM GAA	2.40e-04	9	49	2	SM00018
Domain	Ser/Thr_kinase_AS	RAF1 LIMK1 LIMK2 BUB1 LRRK2 MAP2K5	3.27e-04	357	49	6	IPR008271
Domain	PROTEIN_KINASE_ST	RAF1 LIMK1 LIMK2 BUB1 LRRK2 MAP2K5	3.52e-04	362	49	6	PS00108
Domain	-	MGAM GAA	3.65e-04	11	49	2	4.10.110.10
Domain	P_trefoil_dom	MGAM GAA	4.38e-04	12	49	2	IPR000519
Domain	ABC_A	ABCA10 ABCA9	4.38e-04	12	49	2	IPR026082
Domain	Protein_kinase_ATP_BS	RAF1 LIMK1 LIMK2 BUB1 LRRK2 MAP2K5	4.49e-04	379	49	6	IPR017441
Domain	Pkinase	RAF1 LIMK1 LIMK2 BUB1 LRRK2 MAP2K5	4.62e-04	381	49	6	PF00069
Domain	-	N4BP2 CHD5 LRRK2 CHD3 ABCA10 ABCA9 MX2 DNAH1	6.59e-04	746	49	8	3.40.50.300
Domain	Gal_mutarotase_SF_dom	MGAM GAA	8.94e-04	17	49	2	IPR011013
Domain	PROTEIN_KINASE_ATP	RAF1 LIMK1 LIMK2 BUB1 LRRK2 MAP2K5	1.22e-03	459	49	6	PS00107
Domain	FCH	PACSIN3 PACSIN2	1.51e-03	22	49	2	PF00611
Domain	FCH	PACSIN3 PACSIN2	1.51e-03	22	49	2	SM00055
Domain	P-loop_NTPase	N4BP2 CHD5 LRRK2 CHD3 ABCA10 ABCA9 MX2 DNAH1	1.51e-03	848	49	8	IPR027417
Domain	PHD	CHD5 KDM4A CHD3	1.64e-03	89	49	3	SM00249
Domain	FCH_dom	PACSIN3 PACSIN2	1.65e-03	23	49	2	IPR001060
Domain	Prot_kinase_dom	RAF1 LIMK1 LIMK2 BUB1 LRRK2 MAP2K5	1.68e-03	489	49	6	IPR000719
Domain	Znf_PHD	CHD5 KDM4A CHD3	1.75e-03	91	49	3	IPR001965
Domain	PROTEIN_KINASE_DOM	RAF1 LIMK1 LIMK2 BUB1 LRRK2 MAP2K5	1.75e-03	493	49	6	PS50011
Domain	Chromo_domain	CHD5 CHD3	1.79e-03	24	49	2	IPR023780
Domain	F_BAR	PACSIN3 PACSIN2	1.95e-03	25	49	2	IPR031160
Domain	F_BAR	PACSIN3 PACSIN2	1.95e-03	25	49	2	PS51741
Domain	ZF_PHD_2	CHD5 KDM4A CHD3	1.98e-03	95	49	3	PS50016
Domain	ZF_PHD_1	CHD5 KDM4A CHD3	2.04e-03	96	49	3	PS01359
Domain	Chromo	CHD5 CHD3	2.11e-03	26	49	2	PF00385
Domain	CHROMO_1	CHD5 CHD3	2.44e-03	28	49	2	PS00598
Domain	CHROMO_2	CHD5 CHD3	2.44e-03	28	49	2	PS50013
Domain	Kinase-like_dom	RAF1 LIMK1 LIMK2 BUB1 LRRK2 MAP2K5	2.82e-03	542	49	6	IPR011009
Domain	SNF2_N	CHD5 CHD3	3.18e-03	32	49	2	IPR000330
Domain	Chromodomain-like	CHD5 CHD3	3.18e-03	32	49	2	IPR016197
Domain	SNF2_N	CHD5 CHD3	3.18e-03	32	49	2	PF00176
Domain	Chromo/shadow_dom	CHD5 CHD3	3.38e-03	33	49	2	IPR000953
Domain	CHROMO	CHD5 CHD3	3.38e-03	33	49	2	SM00298
Domain	DNA/RNA_helicase_DEAH_CS	CHD5 CHD3	3.80e-03	35	49	2	IPR002464
Domain	DEAH_ATP_HELICASE	CHD5 CHD3	4.46e-03	38	49	2	PS00690
Domain	Pkinase_Tyr	RAF1 LIMK1 LIMK2	4.70e-03	129	49	3	PF07714
Pathway	PID_CDC42_PATHWAY	RAF1 EPS8 LIMK1 LIMK2	4.91e-05	70	41	4	M81
Pubmed	LIM kinase inhibition reduces breast cancer growth and invasiveness but systemic inhibition does not reduce metastasis in mice.	LIMK1 LIMK2	2.11e-06	2	51	2	23239465
Pubmed	Expression of the short chain fatty acid receptor GPR41/FFAR3 in autonomic and somatic sensory ganglia.	FFAR3 GPR42	2.11e-06	2	51	2	25637492
Pubmed	The small GTPase RhoA regulates the LIMK1/2-cofilin pathway to modulate cytoskeletal dynamics in oocyte meiosis.	LIMK1 LIMK2	2.11e-06	2	51	2	29319181
Pubmed	Selective tracking of FFAR3-expressing neurons supports receptor coupling to N-type calcium channels in mouse sympathetic neurons.	FFAR3 GPR42	2.11e-06	2	51	2	30478340
Pubmed	3-(4-Hydroxy-3-methoxyphenyl) propionic acid contributes to improved hepatic lipid metabolism via GPR41.	FFAR3 GPR42	2.11e-06	2	51	2	38040866
Pubmed	Genetic Inactivation of Free Fatty Acid Receptor 3 Impedes Behavioral Deficits and Pathological Hallmarks in the APPswe Alzheimer's Disease Mouse Model.	FFAR3 GPR42	2.11e-06	2	51	2	35408893
Pubmed	FFAR3 modulates insulin secretion and global gene expression in mouse islets.	FFAR3 GPR42	2.11e-06	2	51	2	26091414
Pubmed	The Diagnostic and Prognostic Value of LIMK1/2: A Pan-Cancer Analysis.	LIMK1 LIMK2	2.11e-06	2	51	2	34686503
Pubmed	GPR41 modulates insulin secretion and gene expression in pancreatic β-cells and modifies metabolic homeostasis in fed and fasting states.	FFAR3 GPR42	2.11e-06	2	51	2	27550964
Pubmed	Intestinal FFA3 mediates obesogenic effects in mice on a Western diet.	FFAR3 GPR42	2.11e-06	2	51	2	35858247
Pubmed	Phosphorylated LIM kinases colocalize with gamma-tubulin in centrosomes during early stages of mitosis.	LIMK1 LIMK2	2.11e-06	2	51	2	18000399
Pubmed	Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms.	FFAR3 GPR42	2.11e-06	2	51	2	22506074
Pubmed	Free fatty acid receptor 3 differentially contributes to β-cell compensation under high-fat diet and streptozotocin stress.	FFAR3 GPR42	2.11e-06	2	51	2	32073900
Pubmed	Different activity regulation and subcellular localization of LIMK1 and LIMK2 during cell cycle transition.	LIMK1 LIMK2	2.11e-06	2	51	2	16455074
Pubmed	The syndapin protein family: linking membrane trafficking with the cytoskeleton.	PACSIN3 PACSIN2	2.11e-06	2	51	2	15226389
Pubmed	Cloning and biochemical characterization of LIMK-2, a protein kinase containing two LIM domains.	LIMK1 LIMK2	2.11e-06	2	51	2	9089416
Pubmed	The effects of propionate and valerate on insulin responsiveness for glucose uptake in 3T3-L1 adipocytes and C2C12 myotubes via G protein-coupled receptor 41.	FFAR3 GPR42	2.11e-06	2	51	2	24748202
Pubmed	The Cognitive Improvement and Alleviation of Brain Hypermetabolism Caused by FFAR3 Ablation in Tg2576 Mice Is Persistent under Diet-Induced Obesity.	FFAR3 GPR42	2.11e-06	2	51	2	36362376
Pubmed	Elevated LIM kinase 1 in nonmetastatic prostate cancer reflects its role in facilitating androgen receptor nuclear translocation.	LIMK1 LIMK2	2.11e-06	2	51	2	25344584
Pubmed	Suppression of LIM Kinase 1 and LIM Kinase 2 Limits Glioblastoma Invasion.	LIMK1 LIMK2	2.11e-06	2	51	2	31641031
Pubmed	Roles of GPR41 and GPR43 in leptin secretory responses of murine adipocytes to short chain fatty acids.	FFAR3 GPR42	2.11e-06	2	51	2	20399779
Pubmed	Sequence polymorphisms provide a common consensus sequence for GPR41 and GPR42.	FFAR3 GPR42	2.11e-06	2	51	2	19630535
Pubmed	Madecassic acid, the contributor to the anti-colitis effect of madecassoside, enhances the shift of Th17 toward Treg cells via the PPARγ/AMPK/ACC1 pathway.	ACACA PPARG	2.11e-06	2	51	2	28358365
Pubmed	Male mice that lack the G-protein-coupled receptor GPR41 have low energy expenditure and increased body fat content.	FFAR3 GPR42	2.11e-06	2	51	2	23110765
Pubmed	LIMK1 and LIMK2 are important for metastatic behavior and tumor cell-induced angiogenesis of pancreatic cancer cells.	LIMK1 LIMK2	2.11e-06	2	51	2	20047470
Pubmed	The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation.	FFAR3 GPR42	2.11e-06	2	51	2	26522986
Pubmed	Involvement of LIMK1/2 in actin assembly during mouse embryo development.	LIMK1 LIMK2	2.11e-06	2	51	2	29943641
Pubmed	Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41.	FFAR3 GPR42	2.11e-06	2	51	2	14722361
Pubmed	Microbial short chain fatty acid metabolites lower blood pressure via endothelial G protein-coupled receptor 41.	FFAR3 GPR42	2.11e-06	2	51	2	27664183
Pubmed	Transient inhibition of LIMKs significantly attenuated central sensitization and delayed the development of chronic pain.	LIMK1 LIMK2	2.11e-06	2	51	2	28669900
Pubmed	LIM kinases: function, regulation and association with human disease.	LIMK1 LIMK2	2.11e-06	2	51	2	17294230
Pubmed	Human GPR42 is a transcribed multisite variant that exhibits copy number polymorphism and is functional when heterologously expressed.	FFAR3 GPR42	2.11e-06	2	51	2	26260360
Pubmed	G protein coupled receptor 41 regulates fibroblast activation in pulmonary fibrosis via Gαi/o and downstream Smad2/3 and ERK1/2 phosphorylation.	FFAR3 GPR42	2.11e-06	2	51	2	37019194
Pubmed	Self-association of LIM-kinase 1 mediated by the interaction between an N-terminal LIM domain and a C-terminal kinase domain.	LIMK1 LIMK2	2.11e-06	2	51	2	8980133
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TRERF1 RAF1 ACACA N4BP2 BUB1 PLEKHA2 CHD3	2.53e-06	418	51	7	34709266
Pubmed	Short-chain fatty acid receptor GPR41-mediated activation of sympathetic neurons involves synapsin 2b phosphorylation.	FFAR3 GPR42	6.32e-06	3	51	2	22673524
Pubmed	Contribution of the ERK5/MEK5 pathway to Ras/Raf signaling and growth control.	RAF1 MAP2K5	6.32e-06	3	51	2	10531364
Pubmed	GPER stabilizes F-actin cytoskeleton and activates TAZ via PLCβ-PKC and Rho/ROCK-LIMK-Cofilin pathway.	LIMK1 LIMK2	6.32e-06	3	51	2	31277940
Pubmed	NGPF2 triggers synaptic scaling up through ALK-LIMK-cofilin-mediated mechanisms.	LIMK1 LIMK2	6.32e-06	3	51	2	34407403
Pubmed	The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids.	FFAR3 GPR42	6.32e-06	3	51	2	12496283
Pubmed	LIMK Regulates Tumor-Cell Invasion and Matrix Degradation Through Tyrosine Phosphorylation of MT1-MMP.	LIMK1 LIMK2	6.32e-06	3	51	2	27116935
Pubmed	Short-chain fatty acids activate GPR41 and GPR43 on intestinal epithelial cells to promote inflammatory responses in mice.	FFAR3 GPR42	6.32e-06	3	51	2	23665276
Pubmed	Microbial short-chain fatty acids modulate CD8+ T cell responses and improve adoptive immunotherapy for cancer.	FFAR3 GPR42	6.32e-06	3	51	2	34210970
Pubmed	Dietary short-chain fatty acid intake improves the hepatic metabolic condition via FFAR3.	FFAR3 GPR42	6.32e-06	3	51	2	31719611
Pubmed	Regulation of ADF/cofilin phosphorylation and synaptic function by LIM-kinase.	LIMK1 LIMK2	6.32e-06	3	51	2	15458846
Pubmed	Regulation of nuclear translocation of HDAC3 by IkappaBalpha is required for tumor necrosis factor inhibition of peroxisome proliferator-activated receptor gamma function.	NFKBIA PPARG	6.32e-06	3	51	2	16371367
Pubmed	Acetate and propionate short chain fatty acids stimulate adipogenesis via GPCR43.	FFAR3 GPR42	6.32e-06	3	51	2	16123168
Pubmed	GPR41 gene expression is mediated by internal ribosome entry site (IRES)-dependent translation of bicistronic mRNA encoding GPR40 and GPR41 proteins.	FFAR3 GPR42	6.32e-06	3	51	2	22493486
Pubmed	A dimeric kinase assembly underlying autophosphorylation in the p21 activated kinases.	RAF1 LIMK1	6.32e-06	3	51	2	16837009
Pubmed	Neuroligin 1 regulates spines and synaptic plasticity via LIMK1/cofilin-mediated actin reorganization.	LIMK1 LIMK2	6.32e-06	3	51	2	26880202
Pubmed	A functional polymorphism of the NFKB1 gene increases the risk for alcoholic liver cirrhosis in patients with alcohol dependence.	NFKBIA PPARG	6.32e-06	3	51	2	19673747
Pubmed	Extracellular ionic locks determine variation in constitutive activity and ligand potency between species orthologs of the free fatty acid receptors FFA2 and FFA3.	FFAR3 GPR42	6.32e-06	3	51	2	23066016
Pubmed	Loss of FFA2 and FFA3 increases insulin secretion and improves glucose tolerance in type 2 diabetes.	FFAR3 GPR42	6.32e-06	3	51	2	25581519
Pubmed	JMJD2A promotes cellular transformation by blocking cellular senescence through transcriptional repression of the tumor suppressor CHD5.	CHD5 KDM4A	6.32e-06	3	51	2	23168260
Pubmed	Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2.	FFAR3 GPR42	6.32e-06	3	51	2	22190648
Pubmed	Microbiota-Derived Short-Chain Fatty Acids Promote the Memory Potential of Antigen-Activated CD8+ T Cells.	FFAR3 GPR42	6.32e-06	3	51	2	31272808
Pubmed	GPR41/FFAR3 and GPR43/FFAR2 as cosensors for short-chain fatty acids in enteroendocrine cells vs FFAR3 in enteric neurons and FFAR2 in enteric leukocytes.	FFAR3 GPR42	6.32e-06	3	51	2	23885020
Pubmed	Dietary Fiber Confers Protection against Flu by Shaping Ly6c- Patrolling Monocyte Hematopoiesis and CD8+ T Cell Metabolism.	FFAR3 GPR42	6.32e-06	3	51	2	29768180
Pubmed	Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41.	FFAR3 GPR42	6.32e-06	3	51	2	18931303
Pubmed	GPR41 and GPR43 regulate CD8+ T cell priming during herpes simplex virus type 1 infection.	FFAR3 GPR42	6.32e-06	3	51	2	38524121
Pubmed	Nischarin inhibits LIM kinase to regulate cofilin phosphorylation and cell invasion.	LIMK1 LIMK2	6.32e-06	3	51	2	18332102
Pubmed	Abnormalities in microbiota/butyrate/FFAR3 signaling in aging gut impair brain function.	FFAR3 GPR42	6.32e-06	3	51	2	38329121
Pubmed	Identification and characterization of a novel family of serine/threonine kinases containing two N-terminal LIM motifs.	LIMK1 LIMK2	1.26e-05	4	51	2	8537403
Pubmed	Olfactory receptor responding to gut microbiota-derived signals plays a role in renin secretion and blood pressure regulation.	FFAR3 GPR42	1.26e-05	4	51	2	23401498
Pubmed	Keratinocyte migration in the developing eyelid requires LIMK2.	LIMK1 LIMK2	1.26e-05	4	51	2	23071748
Pubmed	A cluster of four novel human G protein-coupled receptor genes occurring in close proximity to CD22 gene on chromosome 19q13.1.	FFAR3 GPR42	1.26e-05	4	51	2	9344866
Pubmed	PACSIN 3 is a novel SH3 domain cytoplasmic adapter protein of the pacsin-syndapin-FAP52 gene family.	PACSIN3 PACSIN2	1.26e-05	4	51	2	11179684
Pubmed	Sirtuin1 promotes osteogenic differentiation through downregulation of peroxisome proliferator-activated receptor γ in MC3T3-E1 cells.	ACACA PPARG	1.26e-05	4	51	2	27378422
Pubmed	Short-chain fatty acids and ketones directly regulate sympathetic nervous system via G protein-coupled receptor 41 (GPR41).	FFAR3 GPR42	1.26e-05	4	51	2	21518883
Pubmed	PACSINs bind to the TRPV4 cation channel. PACSIN 3 modulates the subcellular localization of TRPV4.	PACSIN3 PACSIN2	1.26e-05	4	51	2	16627472
Pubmed	A family of fatty acid binding receptors.	FFAR3 GPR42	1.26e-05	4	51	2	15684720
Pubmed	A novel Rho-dependent pathway that drives interaction of fascin-1 with p-Lin-11/Isl-1/Mec-3 kinase (LIMK) 1/2 to promote fascin-1/actin binding and filopodia stability.	LIMK1 LIMK2	1.26e-05	4	51	2	22883572
Pubmed	G-CSF promotes the proliferation of developing cardiomyocytes in vivo and in derivation from ESCs and iPSCs.	CSF3 ACTN2	1.26e-05	4	51	2	20207226
Pubmed	Maternal High Fiber Diet during Pregnancy and Lactation Influences Regulatory T Cell Differentiation in Offspring in Mice.	FFAR3 GPR42	1.26e-05	4	51	2	29021375
Pubmed	Essential role of PACSIN2/syndapin-II in caveolae membrane sculpting.	PACSIN3 PACSIN2	1.26e-05	4	51	2	21610094
Pubmed	Microbial metabolites, short-chain fatty acids, restrain tissue bacterial load, chronic inflammation, and associated cancer in the colon of mice.	FFAR3 GPR42	1.26e-05	4	51	2	29644622
Pubmed	TPPP acts downstream of RhoA-ROCK-LIMK2 to regulate astral microtubule organization and spindle orientation.	LIMK1 LIMK2	2.10e-05	5	51	2	22328514
Pubmed	Fatty acid binding receptors and their physiological role in type 2 diabetes.	FFAR3 GPR42	2.10e-05	5	51	2	19009545
Pubmed	Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells.	FFAR3 GPR42	2.10e-05	5	51	2	24327954
Pubmed	LIM kinase 1 modulates cortical actin and CXCR4 cycling and is activated by HIV-1 to initiate viral infection.	LIMK1 LIMK2	2.10e-05	5	51	2	21321123
Pubmed	Lactate inhibits lipolysis in fat cells through activation of an orphan G-protein-coupled receptor, GPR81.	FFAR3 GPR42	2.10e-05	5	51	2	19047060
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	TRERF1 LIMK1 LIMK2 NFKBIA ZNF254 KDM4A CHD3 ZNF282	2.16e-05	808	51	8	20412781
Pubmed	Cofilin phosphorylation and actin reorganization activities of testicular protein kinase 2 and its predominant expression in testicular Sertoli cells.	LIMK1 LIMK2	3.15e-05	6	51	2	11418599
Pubmed	Genetic predictors of weight loss and weight regain after intensive lifestyle modification, metformin treatment, or standard care in the Diabetes Prevention Program.	NEGR1 PPARG	3.15e-05	6	51	2	22179955
Pubmed	PACSIN proteins bind tubulin and promote microtubule assembly.	PACSIN3 PACSIN2	3.15e-05	6	51	2	18456257
Pubmed	Nf1 RasGAP inhibition of LIMK2 mediates a new cross-talk between Ras and Rho pathways.	LIMK1 LIMK2	3.15e-05	6	51	2	23082153
Pubmed	Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization.	LIMK1 LIMK2	3.15e-05	6	51	2	9655398
Pubmed	All three PACSIN isoforms bind to endocytic proteins and inhibit endocytosis.	PACSIN3 PACSIN2	3.15e-05	6	51	2	11082044
Pubmed	PICK1 interacts with PACSIN to regulate AMPA receptor internalization and cerebellar long-term depression.	PACSIN3 PACSIN2	3.15e-05	6	51	2	23918399
Pubmed	Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase.	LIMK1 LIMK2	3.15e-05	6	51	2	10436159
Pubmed	Free fatty acid receptors act as nutrient sensors to regulate energy homeostasis.	FFAR3 GPR42	3.15e-05	6	51	2	19460454
Pubmed	Role for p21-activated kinase PAK4 in development of the mammalian heart.	LIMK1 LIMK2	3.15e-05	6	51	2	22173944
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	RAF1 ATXN2L AARS1 LIMK1 LIMK2 ACACA N4BP2 PLEKHA2	3.39e-05	861	51	8	36931259
Pubmed	Altered expression of CDC42 signaling pathway components in cortical layer 3 pyramidal cells in schizophrenia.	LIMK1 LIMK2	4.41e-05	7	51	2	25981171
Pubmed	Leucine-rich repeat kinase 2 interacts with p21-activated kinase 6 to control neurite complexity in mammalian brain.	LIMK1 LRRK2	4.41e-05	7	51	2	26375402
Pubmed	Regulation of FasL expression: a SH3 domain containing protein family involved in the lysosomal association of FasL.	PACSIN3 PACSIN2	5.87e-05	8	51	2	16318909
Pubmed	Vagal neuron expression of the microbiota-derived metabolite receptor, free fatty acid receptor (FFAR3), is necessary for normal feeding behavior.	FFAR3 GPR42	5.87e-05	8	51	2	34626852
Pubmed	Anisotropic regulation of Ankrd2 gene expression in skeletal muscle by mechanical stretch.	RAF1 NFKBIA	5.87e-05	8	51	2	20442316
Pubmed	Activation of LIM kinases by myotonic dystrophy kinase-related Cdc42-binding kinase alpha.	LIMK1 LIMK2	5.87e-05	8	51	2	11340065
Pubmed	Filamin-A regulates actin-dependent clustering of HIV receptors.	LIMK1 LIMK2	5.87e-05	8	51	2	17572668
Cytoband	3p25	RAF1 PPARG	1.63e-04	17	51	2	3p25
Cytoband	19q13.1	FFAR3 GPR42	1.73e-03	55	51	2	19q13.1
Cytoband	Ensembl 112 genes in cytogenetic band chr17q24	ABCA10 ABCA9	5.37e-03	98	51	2	chr17q24
GeneFamily	PHD finger proteins\|NuRD complex	CHD5 CHD3	1.98e-04	12	32	2	1305
GeneFamily	ATP binding cassette subfamily A	ABCA10 ABCA9	2.73e-04	14	32	2	805
GeneFamily	Rho GTPase activating proteins\|F-BAR domain containing	PACSIN3 PACSIN2	7.50e-04	23	32	2	1288
GeneFamily	LIM domain containing	LIMK1 LIMK2	4.88e-03	59	32	2	1218
GeneFamily	PHD finger proteins	CHD5 CHD3	1.10e-02	90	32	2	88
Coexpression	GSE3982_EOSINOPHIL_VS_EFF_MEMORY_CD4_TCELL_UP	MGAM LIMK2 CHD5 RSRP1 ADI1 PACSIN2	2.48e-06	200	51	6	M5416
Coexpression	WANG_TNF_TARGETS	LIMK1 CSF3 NFKBIA	1.75e-05	26	51	3	M2308
Coexpression	FIRESTEIN_PROLIFERATION	RAF1 LIMK1 LIMK2 PPARG PACSIN2	1.78e-05	166	51	5	M5354
Coexpression	GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_2H_UP	RAF1 MGAM GAA PACSIN2 CLASRP	4.35e-05	200	51	5	M6090
ToppCell	CTRL-Myeloid-Neutrophil\|Myeloid / Disease state, Lineage and Cell class	MGAM LIMK2 FFAR3 NFKBIA LRRK2 MX2	4.17e-08	170	51	6	151dabe1d240dde414c881bf4fa816c69fa1c32d
ToppCell	CTRL-Myeloid-Neutrophil\|CTRL / Disease state, Lineage and Cell class	MGAM LIMK2 FFAR3 NFKBIA LRRK2 MX2	4.47e-08	172	51	6	ef3a6fe3b7300959f9f71130200c7fb8741c42b0
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 CSF3 NEGR1 ABCA10 ABCA9	1.07e-06	159	51	5	2607b562903228274fbd96168ba826782fab0b53
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 CSF3 NEGR1 ABCA10 ABCA9	1.07e-06	159	51	5	e812cbde59188924c6277c3feadf1a9592fa62a4
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D175\|Adult / Lineage, Cell type, age group and donor	EPS8 AARS1 ACACA CSF3 LRRK2	2.43e-06	188	51	5	ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCell	LA\|World / Chamber and Cluster_Paper	EPS8 NEGR1 PNPLA3 ABCA10 ABCA9	2.76e-06	193	51	5	d4bf89437216baf489ea0239136dcedf3b6714af
ToppCell	BL-critical-LOC-Myeloid-Neutrophil\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MGAM LIMK2 NFKBIA LRRK2 MX2	2.98e-06	196	51	5	f64d7fed31e418c55fe946744d78c3cbecec9bbf
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 NEGR1 ABCA10 ABCA9	2.63e-05	150	51	4	1270f33f9d7e46e55adf1a96e8beee858b95589d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 NEGR1 ABCA10 ABCA9	2.63e-05	150	51	4	156118ce1d69522624196410cba18b8354cd0bb4
ToppCell	CTRL-Myeloid-Monocyte\|CTRL / Disease state, Lineage and Cell class	MGAM CSF3 GPR42 NFKBIA	4.09e-05	168	51	4	13dca90c7b811e4d5e8fa44f5e892e29be9787a6
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 NEGR1 ABCA10 ABCA9	4.09e-05	168	51	4	d19a115365c5415e51c039718d7669de788fcf33
ToppCell	severe_COVID-19-Neutrophil\|World / disease group, cell group and cell class (v2)	MGAM LIMK2 NFKBIA MX2	4.28e-05	170	51	4	dfc807e0dd66179490a258ecbe8eb439e715799d
ToppCell	CTRL-Myeloid-Monocyte\|Myeloid / Disease state, Lineage and Cell class	MGAM CSF3 GPR42 NFKBIA	4.38e-05	171	51	4	bfa01571516a0b24476ae06cb07f56c5579dbd70
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 NEGR1 ABCA10 ABCA9	5.12e-05	178	51	4	78a0c6340001a77f5b2d890b6263f574af2e72da
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DPY19L1 GLRX3 NFKBIA ACTN2	5.12e-05	178	51	4	a0ab20c588e7d43d0320d4779d9ab95c1c86e297
ToppCell	-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	NEGR1 SPHKAP ABCA10 ABCA9	5.23e-05	179	51	4	10fadbaa1b6d21cbf9f354d717cc4c225619f4fd
ToppCell	RA-07._Pericyte\|RA / Chamber and Cluster_Paper	TRERF1 EPS8 PPARG PACSIN2	5.46e-05	181	51	4	8dfb42d096db6c2df9b41303a7199d134d4bff07
ToppCell	RA-07._Pericyte\|World / Chamber and Cluster_Paper	TRERF1 EPS8 PPARG PACSIN2	5.58e-05	182	51	4	2075efeae633550fb2eb026d0dfd741c8252482e
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	EPS8 NEGR1 ABCA10 ABCA9	5.58e-05	182	51	4	fbd5e332df73bf7141c822fa67b76367dc962017
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 NEGR1 ABCA10 ABCA9	5.82e-05	184	51	4	c5436a8e45f471b8d1301abbe9c7879204537f52
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 NEGR1 ABCA10 ABCA9	5.82e-05	184	51	4	e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCell	COVID-19-Heart-Fib_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	EPS8 NEGR1 ABCA10 ABCA9	5.95e-05	185	51	4	8f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCell	COVID-19-kidney-Fibroblast-1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TRERF1 EPS8 NEGR1 ABCA9	6.20e-05	187	51	4	76bfe8c42430a230a8bdf299575c444fb7780f24
ToppCell	control-Myeloid-Neutrophils_4\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	MGAM LIMK2 LRRK2 MX2	6.33e-05	188	51	4	22d76c222fb0e3da08e10191af0090f14e03f2ad
ToppCell	PBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MGAM LIMK2 LRRK2 MX2	6.33e-05	188	51	4	aa46073e2940dc1d2020b2e259bf0fc06cb990ee
ToppCell	PBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MGAM LIMK2 LRRK2 MX2	6.33e-05	188	51	4	04814b78da936a51a497e23060d19ca0d619e250
ToppCell	COVID-19-Heart-Fib_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	EPS8 NEGR1 ABCA10 ABCA9	6.33e-05	188	51	4	fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 NEGR1 ABCA10 ABCA9	6.46e-05	189	51	4	71397e993a77d70b2eeede240bdfc7660b558987
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	EPS8 CSF3 NFKBIA LRRK2	6.46e-05	189	51	4	e90ba6f6d7ba0698d04d84278aa035c28803733e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 NEGR1 ABCA10 ABCA9	6.46e-05	189	51	4	4eea4759520c312bd17a681034d8074e47093d2b
ToppCell	IPF-Myeloid-ncMonocyte\|Myeloid / Disease state, Lineage and Cell class	FFAR3 GPR42 LRRK2 MX2	6.46e-05	189	51	4	5c22d2d935f7bb270260b8bc6be67b565ec401bf
ToppCell	COPD-Myeloid-ncMonocyte\|World / Disease state, Lineage and Cell class	FFAR3 GPR42 LRRK2 MX2	6.59e-05	190	51	4	aece860b5609ad5a8fc920d685f0d0ec71bf9018
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 NEGR1 ABCA10 ABCA9	6.73e-05	191	51	4	39092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 NEGR1 ABCA10 ABCA9	6.73e-05	191	51	4	a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCell	RV-01._Fibroblast_I\|World / Chamber and Cluster_Paper	EPS8 NEGR1 ABCA10 ABCA9	6.73e-05	191	51	4	70c067c54084bfb02c29bab085f4defd477194fb
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MGAM LIMK2 LRRK2 MX2	6.73e-05	191	51	4	b9b091d6b352d5128bb864ff52d2e5fb3387b766
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 NEGR1 ABCA10 ABCA9	6.73e-05	191	51	4	8f6d592edc32fdb901af30501d4360512334e8c2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 NEGR1 ABCA10 ABCA9	6.73e-05	191	51	4	ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 NEGR1 ABCA10 ABCA9	6.87e-05	192	51	4	bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCell	NS-moderate-d_16-33-Myeloid-Neutrophil\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	LIMK2 NFKBIA LRRK2 MX2	6.87e-05	192	51	4	545c3990cbe3c04bfd95a0ab7499d2c4af509be1
ToppCell	NS-critical-d_0-4-Myeloid-Neutrophil\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MGAM LIMK2 NFKBIA LRRK2	6.87e-05	192	51	4	3db74359c30172a51177e00eac1f48f483e15578
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	EPS8 NEGR1 ABCA10 ABCA9	6.87e-05	192	51	4	60b1312e84f6d6448365a952469c506c00b5fe93
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 NEGR1 ABCA10 ABCA9	6.87e-05	192	51	4	5105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCell	IPF-Myeloid-ncMonocyte\|IPF / Disease state, Lineage and Cell class	FFAR3 GPR42 LRRK2 MX2	6.87e-05	192	51	4	e9fb8c57d8094f70fb492909b2bec40aa5f2e5b8
ToppCell	moderate-Myeloid-Neutrophil\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	LIMK2 NFKBIA LRRK2 MX2	6.87e-05	192	51	4	8105408400dac5dcb0ce62b558433257559c9f09
ToppCell	RV-01._Fibroblast_I\|RV / Chamber and Cluster_Paper	EPS8 NEGR1 ABCA10 ABCA9	6.87e-05	192	51	4	356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 NEGR1 ABCA10 ABCA9	6.87e-05	192	51	4	0ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCell	LA-14._Fibroblast_III\|LA / Chamber and Cluster_Paper	CSF3 NEGR1 ABCA10 ABCA9	7.01e-05	193	51	4	7426c291bac59e539c427bcaae18abc7d397d44e
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Mesenchymal-choroid_plexus/mesenchymal-like_cells\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	EPS8 LRRK2 PACSIN3 TNFRSF19	7.01e-05	193	51	4	b6f5a85210e60798205eaf5884cdb540f549d08a
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Mesenchymal\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	EPS8 LRRK2 PACSIN3 TNFRSF19	7.01e-05	193	51	4	e1de67ddada87229f5db0ec193a6da8745a86a64
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 EPS8 NEGR1 ABCA9	7.01e-05	193	51	4	5b602b1702283184bd3943c2a6f2290b7c37e407
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 EPS8 NEGR1 ABCA9	7.01e-05	193	51	4	c8c21eee8c6c086dc2faf416669cd4a002870fbe
ToppCell	COVID-19-Heart-Fib_2\|Heart / Disease (COVID-19 only), tissue and cell type	EPS8 NEGR1 ABCA10 ABCA9	7.15e-05	194	51	4	d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCell	RV-02._Fibroblast_II\|RV / Chamber and Cluster_Paper	EPS8 NEGR1 ABCA10 ABCA9	7.15e-05	194	51	4	11c79a8c56ece42713b04b321982e41e239f07a5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 NEGR1 ABCA10 ABCA9	7.15e-05	194	51	4	81713e0409e8be695ba5dfdc67a997b33435dd9e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 NEGR1 ABCA10 ABCA9	7.15e-05	194	51	4	e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	EPS8 ACACA LRRK2 PACSIN2	7.15e-05	194	51	4	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 NEGR1 ABCA10 ABCA9	7.15e-05	194	51	4	ba7f971fb9a19423602da60770f23d9fead4a451
ToppCell	LA-14._Fibroblast_III\|World / Chamber and Cluster_Paper	CSF3 NEGR1 ABCA10 ABCA9	7.15e-05	194	51	4	803fa83ceada17c38ca9f933b888f7e7b0b90761
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 NEGR1 ABCA10 ABCA9	7.15e-05	194	51	4	cf0244a29934e515446ac917d3c30672b460fb04
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MGAM LIMK2 NFKBIA LRRK2	7.15e-05	194	51	4	4eef50c38e6edb2ef2cdcd14eb50805f6cd65bc8
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 NEGR1 ABCA10 ABCA9	7.15e-05	194	51	4	627cffe2d448e74fc5df92e74e5b922a73304137
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NEGR1 ACTN2 ABCA10 ABCA9	7.29e-05	195	51	4	4243190ad291d56694e2155954dbaa879c9d3844
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 NEGR1 ABCA10 ABCA9	7.29e-05	195	51	4	3c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCell	RV-02._Fibroblast_II\|World / Chamber and Cluster_Paper	EPS8 NEGR1 ABCA10 ABCA9	7.29e-05	195	51	4	ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCell	RA-02._Fibroblast_II\|RA / Chamber and Cluster_Paper	EPS8 NEGR1 ABCA10 ABCA9	7.29e-05	195	51	4	6a02ebbeb3199447ddce64d92d8809436e040eba
ToppCell	COVID-19-Heart-Fib_1\|Heart / Disease (COVID-19 only), tissue and cell type	EPS8 NEGR1 ABCA10 ABCA9	7.29e-05	195	51	4	f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCell	COVID-19-kidney-Fibroblast-2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TRERF1 EPS8 NEGR1 ABCA9	7.29e-05	195	51	4	3d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCell	Control-Myeloid-ncMonocyte\|Control / Disease state, Lineage and Cell class	FFAR3 GPR42 LRRK2 MX2	7.29e-05	195	51	4	fcb05948e7480dc53f06f3fc9b9c3fc129874edd
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NEGR1 ACTN2 ABCA10 ABCA9	7.29e-05	195	51	4	df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NEGR1 ACTN2 ABCA10 ABCA9	7.44e-05	196	51	4	42e9828222a9663525d571633e8a454c30bfa7f8
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MGAM LIMK2 LRRK2 MX2	7.44e-05	196	51	4	fe8d3f45a64323947c36b127355d5940eb56c0ca
ToppCell	IPF-Lymphoid-T\|Lymphoid / Disease state, Lineage and Cell class	TRERF1 N4BP2 NFKBIA PPARG	7.44e-05	196	51	4	6e70c48a63d9673eb16b0847c1bd88eecc2f7a3c
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NEGR1 CHD5 TNFRSF19 ACTN2	7.44e-05	196	51	4	9830fb3da7a60f65ad463e9054bb77c06b025e4d
ToppCell	mild-Myeloid-Neutrophils_4\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	MGAM LIMK2 LRRK2 MX2	7.44e-05	196	51	4	f8c98cded5550843322b1711e1a57c7e88cae861
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MGAM LIMK2 LRRK2 MX2	7.44e-05	196	51	4	526d037bb12d81f1c235c60ddc787fbad0bbad77
ToppCell	mild-Myeloid-Neutrophils_2\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	MGAM LIMK2 LRRK2 MX2	7.44e-05	196	51	4	e9f30eb8a3915c3b2af009c832bff9b349b65ae5
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MGAM LIMK2 LRRK2 MX2	7.58e-05	197	51	4	340ce4fef244176fb52e38ffbcbdfda5ac3467dd
ToppCell	BL-critical-LOC-Myeloid\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MGAM LIMK2 NFKBIA LRRK2	7.58e-05	197	51	4	932a7fae4979b561688e6222505df0f4e510ab11
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 EPS8 NEGR1 ABCA9	7.58e-05	197	51	4	80e153790cef37b743e22a7370ff5b3a6abf147d
ToppCell	severe-Lymphocytic-CD4_T_cells_2\|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	MGAM LIMK2 LRRK2 MX2	7.58e-05	197	51	4	3b71e523d8a68f131def17233385df371db70db5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 NEGR1 ABCA10 ABCA9	7.58e-05	197	51	4	ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 NEGR1 ABCA10 ABCA9	7.58e-05	197	51	4	37f6b6f2809b952382eaebb642b0aad6371f4251
ToppCell	Bronchial-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NEGR1 TNFRSF19 ABCA10 ABCA9	7.58e-05	197	51	4	6806ec223e542f0475303698eb78c1cc527f5c6b
ToppCell	ASK428-Epithelial-Type_2\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	EPS8 CSF3 NFKBIA LRRK2	7.73e-05	198	51	4	ec0d1801363adb70c6a26655b79d12b438c7417d
ToppCell	moderate-Myeloid-Neutrophil\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	LIMK2 NFKBIA LRRK2 MX2	7.73e-05	198	51	4	a6306dac34af5783f3a734ef1eaa7a0c03267b4f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRERF1 EPS8 NEGR1 ABCA9	7.73e-05	198	51	4	79576525a10ed3e3a9d1608077cd16ecda23376f
ToppCell	COVID-19_Severe-Neu_1\|COVID-19_Severe / 5 Neutrophil clusters in COVID-19 patients	LIMK2 NFKBIA LRRK2 MX2	7.73e-05	198	51	4	bbe639ea5a636c985e509fb0a133ae3b60afac5a
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-A_(AT2)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	EPS8 CSF3 NFKBIA LRRK2	7.89e-05	199	51	4	09cf004032e5af912ee0cdde6e24ce3bcf7673cd
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_granulocytic\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MGAM LIMK2 NFKBIA LRRK2	7.89e-05	199	51	4	119807ea333d1dc7743c6b9f03a2c63e09e19541
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MGAM LIMK2 NFKBIA LRRK2	7.89e-05	199	51	4	691e04871cd6cac0ea5fca1b7fd6421df9315db6
ToppCell	LPS_IL1RA_TNF-Hematopoietic_Myeloid-Granulocytic_cells-Neutrophils\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MGAM LIMK2 NFKBIA LRRK2	7.89e-05	199	51	4	8c2ab13b5fffbab3da37041a7000d6537fc4db09
ToppCell	COVID-19_Severe-Neu_1\|World / 5 Neutrophil clusters in COVID-19 patients	LIMK2 NFKBIA LRRK2 MX2	7.89e-05	199	51	4	e4d8bf016fd95a440e30014a75587e097e90cfad
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NEGR1 LRRK2 ABCA10 ABCA9	8.04e-05	200	51	4	b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCell	LPS_IL1RA_TNF-Hematopoietic_Myeloid-Granulocytic_cells\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MGAM LIMK2 NFKBIA LRRK2	8.04e-05	200	51	4	1592ca96c59eb053d0f0915afb337db9f3a40c91
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NEGR1 ACTN2 ABCA10 ABCA9	8.04e-05	200	51	4	e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCell	severe-Neutrophil\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	MGAM LIMK2 LRRK2 MX2	8.04e-05	200	51	4	f9af7e77a8483ab4ae708b55514e64f5420fa0c1
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NEGR1 LRRK2 ABCA10 ABCA9	8.04e-05	200	51	4	0c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	MGAM LIMK2 NFKBIA	2.24e-04	103	51	3	3baaf23a9756be41af3a9b4f720e3ab00f1b674d
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	NFKBIA LRRK2 MX2	2.72e-04	110	51	3	854f21560ce7cb5e1923403b6d04df3d804431e2
Drug	Miglitol	MGAM GAA	4.73e-06	2	50	2	DB00491
Drug	calcium carbonate phosphate	MGAM ACACA	1.42e-05	3	50	2	CID006337635
Drug	N,N'-diethylethylenediamine	MGAM ACACA	1.42e-05	3	50	2	CID000067105
Drug	disodium (R,R)-5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxole-2,3-dicarboxylate	ACACA PNPLA3 PPARG	2.50e-05	26	50	3	ctd:C076126
Drug	Acarbose	MGAM GAA	2.83e-05	4	50	2	DB00284
Drug	steviol	ACACA NFKBIA PPARG	3.88e-05	30	50	3	ctd:C012042
Drug	N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine	RAF1 AARS1 NFKBIA PPARG MAP2K5 MX2	4.10e-05	291	50	6	ctd:C044387
Drug	C6-ceramide	RAF1 LIMK1 LIMK2 NFKBIA	4.38e-05	89	50	4	CID000375405
Drug	(-)-Lentiginosine	MGAM GAA	4.71e-05	5	50	2	CID000130407
Drug	D-gluco-octenitol	MGAM GAA	4.71e-05	5	50	2	CID006438548
Drug	alpha-solasonine	MGAM GAA	4.71e-05	5	50	2	CID000073410
Drug	2-ethyl-3-oxohexanoic acid	ACACA PPARG	4.71e-05	5	50	2	CID013539869
Drug	ngml	MGAM CSF3	4.71e-05	5	50	2	CID000066936
Drug	AC1L1DBR	RAF1 NFKBIA MAP2K5	5.19e-05	33	50	3	CID000002279
Drug	4-hydroxy-2-nonenal	RAF1 EPS8 CSF3 NFKBIA BUB1 ADI1 PPARG MAP2K5 MX2	5.26e-05	798	50	9	ctd:C027576
Drug	Silymarin	RAF1 ACACA CSF3 NFKBIA PPARG	5.29e-05	185	50	5	ctd:D012838
Drug	Dietary Carbohydrates	ACACA NFKBIA RSRP1 PPARG GAA	5.85e-05	189	50	5	ctd:D004040
Drug	Dihydroergotoxine mesylate [8067-24-1]; Down 200; 6.4uM; MCF7; HT_HG-U133A	ATXN2L LIMK1 BUB1 PPARG FOXI1	6.30e-05	192	50	5	4152_DN
Drug	Capsaicin [404-86-4]; Down 200; 13uM; PC3; HT_HG-U133A	LIMK1 LIMK2 BUB1 PACSIN3 CHD3	6.62e-05	194	50	5	4612_DN
Drug	Sertaconazole nitrate [99592-39-9]; Down 200; 8uM; MCF7; HT_HG-U133A	LIMK2 GLRX3 MAP2K5 ZNF282 FOXI1	6.62e-05	194	50	5	6811_DN
Drug	AC1OCFTL	MGAM GAA	7.05e-05	6	50	2	CID006918743
Drug	Clozapine [5786-21-0]; Up 200; 12.2uM; MCF7; HT_HG-U133A	ATXN2L LIMK1 LIMK2 PLEKHA2 MX2	7.12e-05	197	50	5	5630_UP
Drug	Betaxolol hydrochloride [63659-19-8]; Down 200; 11.6uM; PC3; HT_HG-U133A	LIMK1 PACSIN3 CHD3 TUT1 MAP2K5	7.12e-05	197	50	5	4608_DN
Drug	Mor-502	MGAM GAA	9.86e-05	7	50	2	CID003080955
Drug	heptenitol	MGAM GAA	9.86e-05	7	50	2	CID000188267
Drug	6-O-methylglucose	MGAM ACACA	9.86e-05	7	50	2	CID000151009
Drug	AC1L4187	NFKBIA PPARG	9.86e-05	7	50	2	CID000099904
Drug	isomaltotetraose	MGAM GAA	9.86e-05	7	50	2	CID003080783
Drug	IN1304	RAF1 NFKBIA PPARG	1.08e-04	42	50	3	CID004516886
Drug	sargahydroquinoic acid	NFKBIA PPARG	1.31e-04	8	50	2	ctd:C528847
Drug	3,4,5-triCQA	MGAM GAA	1.31e-04	8	50	2	CID006440783
Drug	diclofop	ACACA PPARG	1.31e-04	8	50	2	CID000038687
Drug	casuarictin	MGAM GAA	1.31e-04	8	50	2	CID000073644
Drug	KRN8602	CSF3 MX2	1.31e-04	8	50	2	CID000107869
Drug	valienamine	TRERF1 MGAM ADI1 MX2	1.64e-04	125	50	4	CID000193758
Drug	leucrose	MGAM GAA	1.68e-04	9	50	2	CID000165577
Drug	AC1L3ZED	NFKBIA PPARG	1.68e-04	9	50	2	CID000124949
Drug	AC1L46N3	MGAM GAA	1.68e-04	9	50	2	CID000151590
Drug	AC1L2239	ACACA PPARG	1.68e-04	9	50	2	CID000013609
Drug	N-acetylcysteine	RAF1 CSF3 NFKBIA PACSIN3 PPARG MAP2K5 PACSIN2	1.79e-04	546	50	7	CID000000581
Drug	AC1L1IZE	MGAM AARS1 PNPLA3 DNAH1	1.96e-04	131	50	4	CID000004799
Drug	oleoyl-lysophosphatidic acid	RAF1 LIMK1 LIMK2 PACSIN3 PPARG MAP2K5	2.07e-04	391	50	6	CID000003987
Drug	docetaxel	RAF1 PPARG ABCA10 ABCA9	2.08e-04	133	50	4	ctd:C067311
Drug	nectrisine	MGAM GAA	2.10e-04	10	50	2	CID000122106
Drug	AC1NUP8U	MGAM PPARG	2.10e-04	10	50	2	CID005487216
Drug	sitostanol	MGAM C6orf15	2.10e-04	10	50	2	CID000006743
Drug	AC1L3M0Q	MGAM GAA	2.10e-04	10	50	2	CID000118008
Drug	Dfj	MGAM GAA	2.10e-04	10	50	2	CID009549198
Drug	heptitol	MGAM GAA	2.10e-04	10	50	2	CID000101748
Drug	trehazolin	MGAM GAA	2.10e-04	10	50	2	CID003081797
Drug	paclobutrazol	ACACA PPARG	2.10e-04	10	50	2	ctd:C053370
Drug	1q65	AARS1 ACACA C6orf15	2.28e-04	54	50	3	CID000448017
Drug	Alfadexum	MGAM ACACA CSF3	2.28e-04	54	50	3	CID000024796
Drug	lard	ACACA PPARG MX2	2.41e-04	55	50	3	ctd:C029310
Drug	oleoyl-estrone	ACACA PNPLA3 PPARG	2.41e-04	55	50	3	ctd:C108709
Drug	Fatty Acids, Nonesterified	ACACA NFKBIA PPARG	2.54e-04	56	50	3	ctd:D005230
Drug	5-MSL	MGAM GAA	2.57e-04	11	50	2	CID000165311
Drug	ajoene	NFKBIA PPARG	2.57e-04	11	50	2	ctd:C048980
Drug	glucosyl fluoride	MGAM GAA	2.57e-04	11	50	2	CID000150967
Drug	FG5P	MGAM GAA	2.57e-04	11	50	2	CID000127486
Drug	M57-15	CSF3 PPARG	2.57e-04	11	50	2	CID000087583
Drug	trehalulose	MGAM GAA	2.57e-04	11	50	2	CID000162104
Drug	9 Da	MGAM ACACA	2.57e-04	11	50	2	CID005287565
Drug	AC1NUSO2	MGAM GAA	2.57e-04	11	50	2	CID005460006
Drug	Deoxycholic Acid	RAF1 CSF3 NFKBIA PPARG	2.60e-04	141	50	4	ctd:D003840
Drug	propionate	MGAM ACACA GLRX3 FFAR3 GPR42	2.70e-04	262	50	5	CID000001032
Drug	mangiferin	RAF1 ACACA CSF3 NFKBIA	2.75e-04	143	50	4	ctd:C013592
Drug	Fro	CSF3 BUB1 CHD3	2.82e-04	58	50	3	CID011840944
Drug	naringin	RAF1 ACACA NFKBIA PPARG	2.97e-04	146	50	4	ctd:C005274
Drug	osthol	NFKBIA PPARG	3.08e-04	12	50	2	ctd:C046627
Drug	Amrubicin [inn]	NFKBIA MX2	3.08e-04	12	50	2	CID000178149
Drug	Saponins	RAF1 NFKBIA PPARG	3.28e-04	61	50	3	ctd:D012503
Drug	Topo	ACACA CSF3 GAA MX2	3.55e-04	153	50	4	CID000065577
Drug	mannan	MGAM CSF3 GAA	3.61e-04	63	50	3	CID000000870
Drug	P-38	RAF1 LIMK1 CSF3 FFAR3 NFKBIA PPARG MAP2K5	3.62e-04	613	50	7	CID000200878
Drug	AC1L9AGE	MGAM GAA	3.63e-04	13	50	2	CID000441043
Drug	AC1NT9LE	NFKBIA PPARG	3.63e-04	13	50	2	CID005375507
Drug	MDL 25,637	MGAM GAA	3.63e-04	13	50	2	CID000128548
Drug	nitinol	NEGR1 ADI1	3.63e-04	13	50	2	CID003081502
Drug	valiolamine	MGAM GAA	3.63e-04	13	50	2	CID000174312
Drug	methyl 1'-epiacarviosin	MGAM GAA	3.63e-04	13	50	2	CID000197426
Drug	isoacarbose	MGAM GAA	3.63e-04	13	50	2	CID000449165
Drug	galloylglucose	MGAM GAA	3.63e-04	13	50	2	CID000124375
Disease	melanoma	RAF1 CSF3 TNFRSF19 KDM4A PPARG MX2	3.87e-06	248	50	6	C0025202
Disease	pancreatic carcinoma (biomarker_via_orthology)	RAF1 CHD3	8.43e-06	3	50	2	DOID:4905 (biomarker_via_orthology)
Disease	apolipoprotein B measurement	RAF1 NYNRIN C6orf15 RSRP1 PPARG ABCA10 ABCA9 CLASRP	1.45e-05	663	50	8	EFO_0004615
Disease	neutrophil percentage of granulocytes	TRERF1 LIMK2 CSF3 NFKBIA PPARG	4.21e-05	228	50	5	EFO_0007994
Disease	eosinophil percentage of granulocytes	TRERF1 LIMK2 CSF3 NFKBIA PPARG	4.76e-05	234	50	5	EFO_0007996
Disease	Cancer of Nasopharynx	NFKBIA TNFRSF19	1.01e-04	9	50	2	C0238301
Disease	cognitive disorder (is_implicated_in)	CSF3 PPARG	1.01e-04	9	50	2	DOID:1561 (is_implicated_in)
Disease	Colorectal Neoplasms	CHD5 BUB1 PPARG ABCA10 ABCA9	1.05e-04	277	50	5	C0009404
Disease	prostate cancer (is_marker_for)	RAF1 NFKBIA KDM4A MAP2K5	1.43e-04	156	50	4	DOID:10283 (is_marker_for)
Disease	Adult Hodgkin Lymphoma	CSF3 NFKBIA	2.17e-04	13	50	2	C0220597
Disease	Hodgkin lymphoma, lymphocyte depletion	CSF3 NFKBIA	2.17e-04	13	50	2	C0152267
Disease	Mixed Cellularity Hodgkin Lymphoma	CSF3 NFKBIA	2.17e-04	13	50	2	C0152266
Disease	Lymphocyte Rich Classical Hodgkin Lymphoma	CSF3 NFKBIA	2.17e-04	13	50	2	C1266194
Disease	Nodular Lymphocyte Predominant Hodgkin Lymphoma	CSF3 NFKBIA	2.17e-04	13	50	2	C1334968
Disease	Williams-Beuren syndrome (implicated_via_orthology)	LIMK1 LIMK2	2.91e-04	15	50	2	DOID:1928 (implicated_via_orthology)
Disease	gliosarcoma	NFKBIA PPARG	3.33e-04	16	50	2	C0206726
Disease	taste liking measurement	ATXN2L MGAM LIMK2 NEGR1 MAP2K5	4.99e-04	388	50	5	EFO_0010155
Disease	Hodgkin Disease	CSF3 NFKBIA	6.36e-04	22	50	2	C0019829
Disease	Ovarian Serous Adenocarcinoma	RAF1 LRRK2	6.96e-04	23	50	2	C1335177
Disease	Malignant neoplasm of pancreas	NFKBIA BUB1 PPARG	6.99e-04	102	50	3	C0346647
Disease	Hypertrophic obstructive cardiomyopathy	RAF1 GAA	8.23e-04	25	50	2	C4551472
Disease	Myocardial Failure	ACACA CSF3 PPARG	8.70e-04	110	50	3	C1959583
Disease	Congestive heart failure	ACACA CSF3 PPARG	8.70e-04	110	50	3	C0018802
Disease	Heart failure	ACACA CSF3 PPARG	8.70e-04	110	50	3	C0018801
Disease	Left-Sided Heart Failure	ACACA CSF3 PPARG	8.70e-04	110	50	3	C0023212
Disease	Heart Failure, Right-Sided	ACACA CSF3 PPARG	8.70e-04	110	50	3	C0235527
Disease	Heart Decompensation	ACACA CSF3 PPARG	8.70e-04	110	50	3	C1961112
Disease	very low density lipoprotein cholesterol measurement	NYNRIN RSRP1 PNPLA3 ABCA10	9.87e-04	260	50	4	EFO_0008317
Disease	anterior thigh muscle fat infiltration measurement	ATXN2L PPARG	1.03e-03	28	50	2	EFO_0020936
Disease	Colorectal Carcinoma	ACACA CHD5 BUB1 PPARG ABCA10 ABCA9	1.16e-03	702	50	6	C0009402
Disease	caudate nucleus volume	ATXN2L PPARG	1.19e-03	30	50	2	EFO_0004830
Disease	bowel opening frequency	FFAR3 GPR42	1.19e-03	30	50	2	EFO_0600084
Disease	Huntington's disease (implicated_via_orthology)	PACSIN3 PACSIN2	1.35e-03	32	50	2	DOID:12858 (implicated_via_orthology)
Disease	Cardiomyopathies	RAF1 ACTN2 GAA	1.41e-03	130	50	3	C0878544
Disease	posterior thigh muscle fat infiltration measurement	ATXN2L PPARG	1.62e-03	35	50	2	EFO_0020934
Disease	platelet component distribution width	NYNRIN LRRK2 RSRP1 PPARG GAA PACSIN2	1.68e-03	755	50	6	EFO_0007984

Protein segments in the cluster

Peptide	Gene	Start	Entry
APFNNWMEGAMEDLQ	ACTN2	526	P35609
PPDAIAGLQAEWMQM	BUB1	711	O43683
AFLNAIMRWGMPPQD	CHD5	1431	Q8TDI0
IMRWGMPPQDAFNSH	CHD5	1436	Q8TDI0
PFTGMDPEGQQQMWQ	ABCA10	1366	Q8WWZ4
EPSTGMDPEGQQQMW	ABCA9	1446	Q8IUA7
GIAFMGPPSQAMWAL	ACACA	226	Q13085
DMSNGWDPNEMFKFN	ATXN2L	246	Q8WWM7
WMAPEVIRMQDNNPF	RAF1	511	P04049
AWMMALPFCGPNAVD	OR10A7	161	Q8NGE5
QSVDFPWAAVDNMMV	NEGR1	36	Q7Z3B1
PWAPQCAQMNEVMAE	GLRX3	41	O76003
VVGNPYWMAPEMLNG	LIMK2	506	P53671
GMWIDMNEPSSFVNG	MGAM	1416	O43451
DGMWIDMNEPSSFVN	MGAM	2311	O43451
MLWLALGPFPAMENQ	MAP2K5	1	Q13163
SEGMDPEVAMPSWAN	PNPLA3	266	Q9NST1
EAPSFLNGVWMIMND	DPY19L1	76	Q2PZI1
AQAAGVMMQPDDWPF	KDM4A	861	O75164
MQSLMGPQDVGNDWE	LRRK2	96	Q5S007
NDNMKFEWSPAPMVQ	LY6L	81	H3BQJ8
MFQAAERPQEWAMEG	NFKBIA	1	P25963
RMVEAANGMHWPLPF	GPR42	71	O15529
FRANHGPGMAMNWPQ	PACSIN2	286	Q9UNF0
PPEDPWQMMAAAAED	C6orf15	111	Q6UXA7
MFDGPVDAIWIENMN	DNAH1	1946	Q9P2D7
PDGQIWANMDPEERM	HYLS1	6	Q96M11
LNAVMRWGMPPQDAF	CHD3	1421	Q12873
RMVEAANGMHWPLPF	FFAR3	71	O14843
MAFPGQSDTKMQWPE	IDI2-AS1	1	Q9NZ38
PFDGMWIDMNEPSNF	GAA	511	P10253
WQQMEELGMAPALQP	CSF3	151	P09919
PPMDTQNWVFVKEGM	FAM47A	41	Q5JRC9
GWEPPMLNFMGATME	EPS8	436	Q12929
DWANPMPTNMLSYGG	FOXI1	336	Q12951
MLLSGGDPPAQEWFM	NYNRIN	1	Q9P2P1
STHGPGMAMNWPQFE	PACSIN3	286	Q9UKS6
WYMDNPQNLAMGAGA	PLEKHA2	41	Q9HB19
EFSMVDGMWQAQGYP	SPHKAP	1051	Q2M3C7
MVDTEMPFWPTNFGI	PPARG	31	P37231
MSNYVNDMWPGSPQE	RSRP1	1	Q9BUV0
ESPVNMMPWQGDTNN	CLASRP	61	Q8N2M8
NEVQMNVDGPNPWMF	UTP14C	361	Q5TAP6
ILPGNMKDNFWEMGD	AARS1	166	P49588
VGEMVQDWAMQSPGQ	TUT1	696	Q9H6E5
AAAPGVAMNGWMPAR	nan	156	Q8N9P0
CGEFSDAWPLMQNPM	TNFRSF19	301	Q9NS68
DAWPLMQNPMGGDNI	TNFRSF19	306	Q9NS68
MCPHFAQDLWPEQGM	ZNF254	86	O75437
EMAEGMPPMQAQEWD	ZNF282	46	Q9UDV7
LANSNMMWGAPAQAE	TRERF1	101	Q96PN7
MMWGAPAQAEPTDGY	TRERF1	106	Q96PN7
MVQAWYMDDAPGDPR	ADI1	1	Q9BV57
GNPYWMAPEMINGRS	LIMK1	511	P53667
PQMMFPPNWQGAEKD	MX2	41	P20592
PMWNPMIPAFDLFQG	N4BP2	361	Q86UW6