Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncarbohydrate:proton symporter activity

SLC45A2 SLC45A1 SLC2A9

1.38e-078283GO:0005351
GeneOntologyMolecularFunctiontransporter activity

TMEM30B SLC35F2 SLC45A2 SLC45A1 SLC11A1 SLC2A9 SLCO1C1 SLC7A7 SLC22A17 PIEZO1 RHAG

6.00e-0712892811GO:0005215
GeneOntologyMolecularFunctioncarbohydrate:monoatomic cation symporter activity

SLC45A2 SLC45A1 SLC2A9

1.66e-0617283GO:0005402
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC35F2 SLC45A2 SLC45A1 SLC11A1 SLC2A9 SLCO1C1 SLC7A7 SLC22A17 PIEZO1 RHAG

2.46e-0611802810GO:0022857
GeneOntologyMolecularFunctionD-glucose transmembrane transporter activity

SLC45A2 SLC45A1 SLC2A9

5.56e-0625283GO:0055056
GeneOntologyMolecularFunctionhexose transmembrane transporter activity

SLC45A2 SLC45A1 SLC2A9

5.56e-0625283GO:0015149
GeneOntologyMolecularFunctionsolute:proton symporter activity

SLC45A2 SLC45A1 SLC2A9

5.56e-0625283GO:0015295
GeneOntologyMolecularFunctionD-glucose:proton symporter activity

SLC45A2 SLC45A1

5.68e-063282GO:0005356
GeneOntologyMolecularFunctionhexose:proton symporter activity

SLC45A2 SLC45A1

5.68e-063282GO:0009679
GeneOntologyMolecularFunctionmonosaccharide transmembrane transporter activity

SLC45A2 SLC45A1 SLC2A9

7.06e-0627283GO:0015145
GeneOntologyMolecularFunctionsugar transmembrane transporter activity

SLC45A2 SLC45A1 SLC2A9

8.80e-0629283GO:0051119
GeneOntologyMolecularFunctionsucrose transmembrane transporter activity

SLC45A2 SLC45A1

1.14e-054282GO:0008515
GeneOntologyMolecularFunctionsucrose:proton symporter activity

SLC45A2 SLC45A1

1.14e-054282GO:0008506
GeneOntologyMolecularFunctionoligosaccharide transmembrane transporter activity

SLC45A2 SLC45A1

1.14e-054282GO:0015157
GeneOntologyMolecularFunctiondisaccharide transmembrane transporter activity

SLC45A2 SLC45A1

1.14e-054282GO:0015154
GeneOntologyMolecularFunctionsucrose:monoatomic cation symporter activity

SLC45A2 SLC45A1

1.14e-054282GO:0009669
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

PGA4 PGA5 PGA3

1.86e-0537283GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

PGA4 PGA5 PGA3

2.02e-0538283GO:0070001
GeneOntologyMolecularFunctioncarbohydrate transmembrane transporter activity

SLC45A2 SLC45A1 SLC2A9

2.73e-0542283GO:0015144
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC45A2 SLC45A1 SLC11A1 SLC2A9 SLCO1C1

5.14e-05296285GO:0015291
GeneOntologyMolecularFunctionproton transmembrane transporter activity

SLC45A2 SLC45A1 SLC11A1 SLC2A9

1.31e-04188284GO:0015078
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC45A2 SLC45A1 SLC11A1 SLC2A9 SLCO1C1

4.75e-04477285GO:0022804
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC45A2 SLC45A1 SLC2A9

6.06e-04119283GO:0015294
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC45A2 SLC45A1 SLC11A1 SLC2A9

7.79e-04301284GO:0022853
GeneOntologyMolecularFunctionsymporter activity

SLC45A2 SLC45A1 SLC2A9

1.19e-03150283GO:0015293
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC45A2 SLC45A1 SLC11A1 SLC2A9 RHAG

1.62e-03627285GO:0022890
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC45A2 SLC45A1 SLC11A1 SLC2A9 PIEZO1

2.09e-03664285GO:0008324
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC45A2 SLC45A1 SLC11A1 SLC2A9 RHAG

3.70e-03758285GO:0015318
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC45A2 SLC45A1 SLC11A1 SLC2A9 PIEZO1

4.48e-03793285GO:0015075
GeneOntologyMolecularFunctionorganic cation transmembrane transporter activity

SLC7A7 RHAG

6.02e-0383282GO:0015101
GeneOntologyMolecularFunctionendopeptidase activity

PGA4 PGA5 PGA3

2.18e-02430283GO:0004175
GeneOntologyBiologicalProcessoligosaccharide transport

SLC45A2 SLC45A1

8.45e-064252GO:0015772
GeneOntologyBiologicalProcesssucrose transport

SLC45A2 SLC45A1

8.45e-064252GO:0015770
GeneOntologyBiologicalProcessdisaccharide transport

SLC45A2 SLC45A1

8.45e-064252GO:0015766
GeneOntologyBiologicalProcessL-arginine transmembrane transport

SLC11A1 SLC7A7

1.47e-0415252GO:1903826
GeneOntologyBiologicalProcessbasic amino acid transmembrane transport

SLC11A1 SLC7A7

2.38e-0419252GO:1990822
GeneOntologyBiologicalProcessbasic amino acid transport

SLC11A1 SLC7A7

3.21e-0422252GO:0015802
GeneOntologyBiologicalProcessorganic anion transport

SLC11A1 SLC2A9 SLCO1C1 SLC7A7 RHAG

3.34e-04515255GO:0015711
GeneOntologyCellularComponentmultivesicular body lumen

PGA4 PGA5 PGA3

7.51e-087283GO:0097486
GeneOntologyCellularComponentlate endosome lumen

PGA4 PGA5 PGA3

3.53e-0711283GO:0031906
GeneOntologyCellularComponentendosome lumen

PGA4 PGA5 PGA3

2.56e-0543283GO:0031904
GeneOntologyCellularComponentmultivesicular body

PGA4 PGA5 PGA3

2.19e-0488283GO:0005771
GeneOntologyCellularComponentlate endosome

PGA4 SLC11A1 PGA5 PGA3

1.13e-03348284GO:0005770
DomainAspartic_peptidase_N

PGA4 PGA5 PGA3

1.05e-077283IPR012848
DomainA1_Propeptide

PGA4 PGA5 PGA3

1.05e-077283PF07966
DomainAspartic_peptidase_A1

PGA4 PGA5 PGA3

3.60e-0710283IPR001461
DomainPEPTIDASE_A1

PGA4 PGA5 PGA3

3.60e-0710283PS51767
DomainPEPTIDASE_A1

PGA4 PGA5 PGA3

3.60e-0710283IPR033121
DomainAsp

PGA4 PGA5 PGA3

3.60e-0710283PF00026
DomainASP_PROTEASE

PGA4 PGA5 PGA3

6.58e-0712283PS00141
Domain-

PGA4 PGA5 PGA3

6.58e-07122832.40.70.10
DomainAspartic_peptidase_AS

PGA4 PGA5 PGA3

8.54e-0713283IPR001969
DomainPeptidase_aspartic_dom

PGA4 PGA5 PGA3

2.02e-0617283IPR021109
DomainMFS_dom

SLC45A2 SLC2A9 SLCO1C1 SLC22A17

4.54e-05134284IPR020846
DomainMFS

SLC45A2 SLC45A1 SLC22A17

2.05e-0477283IPR011701
DomainMFS_1

SLC45A2 SLC45A1 SLC22A17

2.05e-0477283PF07690
DomainMFS

SLC2A9 SLCO1C1 SLC22A17

5.54e-04108283PS50850
DomainSUGAR_TRANSPORT_1

SLC2A9 SLC22A17

5.86e-0424282PS00216
DomainSugar_transporter_CS

SLC2A9 SLC22A17

1.05e-0332282IPR005829
DomainSugar_tr

SLC2A9 SLC22A17

1.32e-0336282PF00083
DomainMFS_sugar_transport-like

SLC2A9 SLC22A17

1.32e-0336282IPR005828
PathwayWP_GASTRIC_ACID_PRODUCTION

PGA4 PGA5 PGA3

3.40e-0711193M39726
PathwayREACTOME_SURFACTANT_METABOLISM

PGA4 PGA5 PGA3

8.24e-0630193M27566
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC11A1 SLC2A9 SLCO1C1 SLC7A7 RHAG

1.26e-05238195MM15076
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC11A1 SLC2A9 SLCO1C1 SLC7A7 RHAG

1.57e-05249195M5988
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC11A1 SLC2A9 SLCO1C1 SLC7A7 SLC22A17 RHAG

1.96e-04681196MM14985
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC11A1 SLC2A9 SLCO1C1 SLC7A7 SLC22A17 RHAG

3.00e-04736196M27287
PathwayREACTOME_SLC_TRANSPORTER_DISORDERS

SLC2A9 SLC7A7 RHAG

3.00e-0499193M27474
PathwayREACTOME_DISORDERS_OF_TRANSMEMBRANE_TRANSPORTERS

SLC2A9 SLC7A7 RHAG

1.63e-03177193M27476
Pubmed

Localization of pepsinogen (A and C) and cellular differentiation of pepsinogen-synthesizing cells in the human gastric mucosa.

PGA4 PGA5 PGA3

4.67e-1032832032552
Pubmed

Close linkage of human chromosomal pepsinogen A genes.

PGA4 PGA5 PGA3

4.67e-1032833017318
Pubmed

Serum pepsinogen test for early detection of gastric cancer in a European country.

PGA4 PGA5 PGA3

4.67e-10328321989121
Pubmed

Helicobacter pylori infection and serum pepsinogen A, pepsinogen C, and gastrin in gastritis and peptic ulcer: significance of inflammation and effect of bacterial eradication.

PGA4 PGA5 PGA3

4.67e-1032838053437
Pubmed

Serum antibodies to H+,K+-ATPase, serum pepsinogen A and Helicobacter pylori in relation to gastric mucosa morphology in patients with low or low-normal concentrations of serum cobalamins.

PGA4 PGA5 PGA3

4.67e-1032839855083
Pubmed

Advantages of serum pepsinogen A combined with gastrin or pepsinogen C as first-line analytes in the evaluation of suspected cobalamin deficiency: a study in patients previously not subjected to gastrointestinal surgery.

PGA4 PGA5 PGA3

4.67e-1032839797498
Pubmed

The glomerular sieving of pepsinogen A and C in man.

PGA4 PGA5 PGA3

4.67e-1032832478370
Pubmed

Analysis of the promoter of a human pepsinogen A gene.

PGA4 PGA5 PGA3

4.67e-1032831812762
Pubmed

O6-methylguanine in blood leucocyte DNA: an association with the geographic prevalence of gastric cancer and with low levels of serum pepsinogen A, a marker of severe chronic atrophic gastritis. The EUROGAST Study Group.

PGA4 PGA5 PGA3

4.67e-1032837923573
Pubmed

Family and population studies on the human pepsinogen A multigene family.

PGA4 PGA5 PGA3

4.67e-1032832566575
Pubmed

Fast detection of phosphorylation of human pepsinogen A, human pepsinogen C and swine pepsinogen using a combination of reversed-phase high-performance liquid chromatography and capillary zone electrophoresis for peptide mapping.

PGA4 PGA5 PGA3

4.67e-1032839061458
Pubmed

Ratio between serum IL-8 and pepsinogen A/C: a marker for atrophic body gastritis.

PGA4 PGA5 PGA3

4.67e-10328312588289
Pubmed

Clinical significance of pepsinogen A isozymogens, serum pepsinogen A and C levels, and serum gastrin levels.

PGA4 PGA5 PGA3

4.67e-1032833815274
Pubmed

Immunoblot technique to visualise serum pepsinogen A isozymogen patterns.

PGA4 PGA5 PGA3

4.67e-1032832229438
Pubmed

Prediction of gastric cancer development by serum pepsinogen test and Helicobacter pylori seropositivity in Eastern Asians: a systematic review and meta-analysis.

PGA4 PGA5 PGA3

4.67e-10328325314140
Pubmed

Validation of the pepsinogen test method for gastric cancer screening using a follow-up study.

PGA4 PGA5 PGA3

4.67e-10328319890696
Pubmed

Pepsinogens: physiology, pharmacology pathophysiology and exercise.

PGA4 PGA5 PGA3

4.67e-10328310675278
Pubmed

Gastric cancer detection using gastric juice pepsinogen and melanoma-associated gene RNA.

PGA4 PGA5 PGA3

4.67e-10328323897256
Pubmed

An aspartic proteinase expressed in the yolk sac and neonatal stomach of the mouse.

PGA4 PGA5 PGA3

4.67e-10328311566730
Pubmed

The effect of acute and chronic protein loading on urinary pepsinogen A excretion.

PGA4 PGA5 PGA3

4.67e-1032831956484
Pubmed

The epidemiology of low serum pepsinogen A levels and an international association with gastric cancer rates. EUROGAST Study Group.

PGA4 PGA5 PGA3

4.67e-1032837926498
Pubmed

Transcription regulation of human and porcine pepsinogen A.

PGA4 PGA5 PGA3

4.67e-1032838540382
Pubmed

Pepsinogen A polymorphism in gastric mucosa and urine, with special reference to patients with gastric cancer.

PGA4 PGA5 PGA3

4.67e-1032833780036
Pubmed

Crystal structure of human pepsinogen A.

PGA4 PGA5 PGA3

4.67e-1032839561228
Pubmed

Diagnostic value of serum pepsinogen C in patients with raised serum concentrations of pepsinogen A.

PGA4 PGA5 PGA3

4.67e-1032838244094
Pubmed

The combination of serum trefoil factor 3 and pepsinogen testing is a valid non-endoscopic biomarker for predicting the presence of gastric cancer: a new marker for gastric cancer risk.

PGA4 PGA5 PGA3

4.67e-10328321455714
Pubmed

Plasma pepsinogens, antibodies against Helicobacter pylori, and risk of gastric cancer in the Shanghai Women's Health Study Cohort.

PGA4 PGA5 PGA3

4.67e-10328321407214
Pubmed

Serum pepsinogen level, atrophic gastritis and the risk of incident pancreatic cancer--a prospective cohort study.

PGA4 PGA5 PGA3

4.67e-10328319800305
Pubmed

Identification of a Glu greater than Lys substitution in the activation segment of human pepsinogen A-3 and -5 isozymogens by peptide mapping using endoproteinase Lys-C.

PGA4 PGA5 PGA3

4.67e-1032832901984
Pubmed

Exploratory findings of audiometry in adult patients with otitis media with high pepsinogen concentrations: a preliminary study.

PGA4 PGA5 PGA3

4.67e-10328322992016
Pubmed

The role of serum pepsinogen in the detection of gastric cancer.

PGA4 PGA5 PGA3

4.67e-10328320981206
Pubmed

Assignment of human pepsinogen A locus to the q12-pter region of chromosome 11.

PGA4 PGA5 PGA3

4.67e-1032833839486
Pubmed

Isolation of an activation intermediate and determination of the amino acid sequence of the activation segment of human pepsinogen A.

PGA4 PGA5 PGA3

4.67e-1032836774973
Pubmed

Gastric chief cell-specific transcription of the pepsinogen A gene.

PGA4 PGA5 PGA3

4.67e-1032838504820
Pubmed

Detection of pepsinogen in the neonatal lung and stomach by immunohistochemistry.

PGA4 PGA5 PGA3

4.67e-10328321970995
Pubmed

Serum pepsinogen reference intervals in apparently healthy Chinese population with latex enhanced turbidimetric immunoassay.

PGA4 PGA5 PGA3

4.67e-10328324170207
Pubmed

Primary structure of human pepsinogen gene.

PGA4 PGA5 PGA3

4.67e-1032836300126
Pubmed

Pepsinogen I/II ratio is related to glucose, triacylglycerol, and uric acid levels.

PGA4 PGA5 PGA3

4.67e-10328322304859
Pubmed

Pepsinogen I and II expressions in situ and their correlations with serum pesignogen levels in gastric cancer and its precancerous disease.

PGA4 PGA5 PGA3

4.67e-10328324004680
Pubmed

Effect of enprostil on serum gastrin and pepsinogen A and C levels in patients on long-term treatment with omeprazole.

PGA4 PGA5 PGA3

4.67e-1032838038355
Pubmed

Assignment of the pepsinogen gene complex (PGA) to human chromosome region 11q13 by in situ hybridization.

PGA4 PGA5 PGA3

4.67e-1032833467902
Pubmed

The pepsinogens of human gastric mucosa.

PGA4 PGA5 PGA3

4.67e-1032834586732
Pubmed

Serum pepsinogens in gastric cancer screening.

PGA4 PGA5 PGA3

4.67e-10328320428942
Pubmed

Relationships between the human pepsinogen DNA and protein polymorphisms.

PGA4 PGA5 PGA3

4.67e-1032833014868
Pubmed

Human pepsinogen A isozymogen patterns in serum and gastric mucosa.

PGA4 PGA5 PGA3

4.67e-1032832227273
Pubmed

Genomic structure and evolution of the human pepsinogen A multigene family.

PGA4 PGA5 PGA3

4.67e-1032832892778
Pubmed

The value of serum pepsinogen levels for the diagnosis of gastric diseases in Chinese Han people in midsouth China.

PGA4 PGA5 PGA3

4.67e-10328324383519
Pubmed

The relationship of Helicobacter pylori colonization, the serum pepsinogen A level, and gastric resection.

PGA4 PGA5 PGA3

4.67e-1032839525001
Pubmed

Gene structures of pepsinogens A and C.

PGA4 PGA5 PGA3

4.67e-1032831455184
Pubmed

Evaluation of pepsinogen A and gastrin-17 as markers of gastric cancer and high-risk pathologic conditions.

PGA4 PGA5 PGA3

4.67e-1032837886402
Pubmed

Hypomethylation and expression of pepsinogen A genes in the fundic mucosa of human stomach.

PGA4 PGA5 PGA3

4.67e-1032832831884
Pubmed

Identification of a high risk gastric cancer group using serum pepsinogen after successful eradication of Helicobacter pylori.

PGA4 PGA5 PGA3

4.67e-10328323034090
Pubmed

A possible association of low pepsinogen I and pepsinogen I/II with low and high body weight in Japanese men.

PGA4 PGA5 PGA3

4.67e-10328324125879
Pubmed

Serum pepsinogen and gastric cancer screening.

PGA4 PGA5 PGA3

4.67e-10328317379991
Pubmed

Effects of omeprazole and lansoprazole on fasting and postprandial serum gastrin and serum pepsinogen A and C.

PGA4 PGA5 PGA3

4.67e-1032838751234
Pubmed

Enzyme-linked immunosorbent assay and radioimmunoassay of serum pepsinogen A.

PGA4 PGA5 PGA3

4.67e-1032833554488
Pubmed

The ratio of pepsinogen A to pepsinogen C: a sensitive test for atrophic gastritis.

PGA4 PGA5 PGA3

4.67e-1032832799289
Pubmed

CRYSTALLINE PEPSIN : I. ISOLATION AND TESTS OF PURITY.

PGA4 PGA5 PGA3

4.67e-10328319872561
Pubmed

Human pepsinogen A (PGA): an informative gene complex located at 11q13.

PGA4 PGA5 PGA3

4.67e-1032831968039
Pubmed

Low serum pepsinogen I and pepsinogen I/II ratio and Helicobacter pylori infection are associated with increased risk of gastric cancer: 14-year follow up result in a rural Chinese community.

PGA4 PGA5 PGA3

4.67e-10328321547904
Pubmed

Expression of serum miR-20a-5p, let-7a, and miR-320a and their correlations with pepsinogen in atrophic gastritis and gastric cancer: a case-control study.

PGA4 PGA5 PGA3

4.67e-10328323521833
Pubmed

Serum pepsinogen I/II ratio is correlated with albuminuria in patients with type 2 diabetes.

PGA4 PGA5 PGA3

1.87e-09428323047493
Pubmed

Pepsinogen A and C serum levels in relation to acute NSAID-associated mucosal lesions in healthy volunteers.

PGA4 PGA5 PGA3

1.87e-0942838322031
Pubmed

Transcription factor SOX2 up-regulates stomach-specific pepsinogen A gene expression.

PGA4 PGA5 PGA3

1.87e-09428317136346
Pubmed

Pepsinogen A, pepsinogen C, and gastrin as markers of atrophic chronic gastritis in European dyspeptics.

PGA4 PGA5 PGA3

1.87e-09428312698190
Pubmed

Pepsinogens, progastricsins, and prochymosins: structure, function, evolution, and development.

PGA4 PGA5 PGA3

1.87e-09428311915945
Pubmed

Accuracy and cut-off values of pepsinogens I, II and gastrin 17 for diagnosis of gastric fundic atrophy: influence of gastritis.

PGA4 PGA5 PGA3

4.67e-09528322066020
Pubmed

Glypican-6 and Glypican-4 stimulate embryonic stomach growth by regulating Hedgehog and noncanonical Wnt signaling.

PGA4 PGA5 PGA3

3.78e-071828336057966
Pubmed

Crystal structure of human pepsin and its complex with pepstatin.

PGA4 PGA5

6.25e-0722827663352
Pubmed

Isolation of human, swine, and rat prepepsinogens and calf preprochymosin, and determination of the primary structures of their NH2-terminal signal sequences.

PGA4 PGA5

6.25e-0722822415509
Pubmed

Nucleotide sequence comparison of five human pepsinogen A (PGA) genes: evolution of the PGA multigene family.

PGA4 PGA5

6.25e-0722822714789
Pubmed

Activation of human pepsinogens.

PGA4 PGA5

6.25e-0722823197840
Pubmed

A comparative study on the NH2-terminal amino acid sequences and some other properties of six isozymic forms of human pepsinogens and pepsins.

PGA4 PGA5

1.87e-0632822515193
Pubmed

Multiple roles of epithelial heparan sulfate in stomach morphogenesis.

PGA4 PGA5 PGA3

3.01e-063528329700203
Pubmed

An expression profile analysis of ES cell-derived definitive endodermal cells and Pdx1-expressing cells.

PGA4 PGA5 PGA3

3.56e-063728321362171
Pubmed

Endothelin-2 deficiency causes growth retardation, hypothermia, and emphysema in mice.

PGA4 PGA5 PGA3

4.88e-064128323676500
Pubmed

DNA damage-induced activation of CUL4B targets HUWE1 for proteasomal degradation.

HUWE1 DDB1

6.24e-06528225883150
Pubmed

CRL4BRBBP7 targets HUWE1 for ubiquitination and proteasomal degradation.

HUWE1 DDB1

9.36e-06628229738775
Pubmed

Developmental and cell type-specific expression of thyroid hormone transporters in the mouse brain and in primary brain cells.

SLCO1C1 SLC7A7

2.24e-05928221264952
Pubmed

NEDD4L-mediated Merlin ubiquitination facilitates Hippo pathway activation.

HUWE1 DDB1

2.80e-051028233058421
Pubmed

CRL7SMU1 E3 ligase complex-driven H2B ubiquitylation functions in sister chromatid cohesion by regulating SMC1 expression.

HUWE1 DDB1

9.49e-051828229507117
Pubmed

Characterization of MRFAP1 turnover and interactions downstream of the NEDD8 pathway.

HUWE1 DDB1

1.56e-042328222038470
Pubmed

MLF2 Negatively Regulates P53 and Promotes Colorectal Carcinogenesis.

HUWE1 DDB1

6.89e-044828237438558
InteractionSTXBP3 interactions

TMEM30B SLC35F2 HUWE1 S1PR1

1.25e-05104284int:STXBP3
CytobandEnsembl 112 genes in cytogenetic band chr11q12

PGA4 PGA5 DDB1 PGA3

5.56e-05345284chr11q12
Cytoband11q12.2

PGA4 PGA3

2.62e-043928211q12.2
GeneFamilySolute carriers

SLC35F2 SLC45A2 SLC45A1 SLC11A1 SLC2A9 SLCO1C1 SLC7A7 SLC22A17 RHAG

1.04e-11395169752
GeneFamilyADAM metallopeptidase domain containing|CD molecules

S1PR1 RHAG

4.65e-02394162471
CoexpressionNIKOLSKY_BREAST_CANCER_11Q12_Q14_AMPLICON

PGA4 PGA5 DDB1 PGA3

2.32e-05158284M1493
ToppCellwk_08-11-Hematologic-Myeloid-Neutrophil|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PGA4 SLC11A1 SLC7A7 PGA5 PGA3

1.01e-07185285655fb705d7a029844ecb4f6a53e948e37ee81006
ToppCellwk_08-11-Hematologic-Myeloid-S100A12-hi_cla._mono.|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PGA4 SLC11A1 SLC7A7 PGA5

5.83e-06190284b8c131020d20005cd9f23d26312196f62c958074
ToppCellwk_08-11-Hematologic-Myeloid-CX3CR1+_Mac|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PGA4 SLC7A7 PGA5 PGA3

6.20e-06193284afc20433b5abc9b430751a2aa8d93b0fd136a888
ToppCellTracheal-10x5prime-Immune_Myeloid-Macrophage_other-Macrophage_intravascular|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PGA4 SLC11A1 PGA5 PGA3

7.14e-06200284a1ae299cf77580a6d1a728ee591888b6d70a19d6
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

TMEM30B SLC11A1 SLC2A9

5.49e-051182833cebd17f4688cd43fe1283dc60957e87d5536810
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

TMEM30B SLC11A1 SLC2A9

5.49e-0511828371f63efc641cd07c870f7695118fb244929c1536
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2|Entopeduncular / BrainAtlas - Mouse McCarroll V32

TMEM30B SLC11A1 SLC2A9

5.49e-0511828361b00b001edb1954a5fffaf4dfe71708124a45e5
ToppCellBAL-Control-cDC_7|Control / Compartment, Disease Groups and Clusters

EMC6 SLC35F2 HAS1

5.92e-05121283b49b044a687a31883dfccecf10a183b5ba567f7a
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Rectal_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

PGA4 HHIPL1 SLC11A1

8.37e-05136283feb957df4bff3266cb9a7382b16fc927ae03b9b4
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_1|Cerebellum / BrainAtlas - Mouse McCarroll V32

SLC35F2 SLC45A2 PIEZO1

1.01e-0414528337580218f6a6f65a1d827cbcf59465f8827f9a55
ToppCell390C-Fibroblasts-Fibroblast-F|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

PAQR6 HAS1 PGA3

1.46e-041642832957065d7f1332c5280d47be7cc342286f84be3e
ToppCell390C-Fibroblasts-Fibroblast-F-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

PAQR6 HAS1 PGA3

1.46e-0416428382e57d618c6e59bca4a03d31caf35b6043dfcf52
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage|343B / Donor, Lineage, Cell class and subclass (all cells)

SLC11A1 SLC2A9 SLC7A7

1.76e-04175283d3890bd0c570bb81434fdd1c5229891cefe2e462
ToppCellChildren_(3_yrs)-Immune-enucleated_erythrocyte|Children_(3_yrs) / Lineage, Cell type, age group and donor

S1PR1 SLC22A17 RHAG

1.76e-0417528336cb3c8116bd467ee5da0630d8b3d3e4afcc2ded
ToppCellwk_15-18-Mesenchymal-Mesothelial-intermediate_mesothelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

HHIPL1 DNAJC22 HAS1

1.89e-04179283b1f085e4c8d65d5cdbfaf2db80343638abb08979
ToppCellwk_08-11-Hematologic-Myeloid-APOE+_Mac2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PGA4 SLC7A7 PGA5

2.08e-041852838f843badc0e26cb7300c83db56c7974beb90fcf3
ToppCell3'_v3-lymph-node_spleen-Myeloid_Monocytic-Nonclassical_monocytes|lymph-node_spleen / Manually curated celltypes from each tissue

SLC11A1 SLC7A7 PGA5

2.11e-04186283d7da5edb2ee36f96cdd7e27eb9afcc1cbfd52bb6
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLC11A1 SLC7A7 PGA5

2.18e-0418828348dcbb424771a2f839d65b0c429ef01ad3479a4a
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC35F2 SLCO1C1 S1PR1

2.18e-041882834dc89c7843ebd078e3414e835c56f11fa27f0c5f
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC35F2 SLCO1C1 S1PR1

2.18e-04188283d577b3c2a844e3062c7ca9e9ebc1722d0ac95caa
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC35F2 SLCO1C1 S1PR1

2.18e-041882831e788b60dd643bf220d8dfafa82d85fd083cbc71
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC45A1 HAS1 SLC2A9

2.21e-04189283f7d57723b8fb0f1e1485f51e3eff93ec0f39761e
ToppCellNS-critical-d_16-33-Myeloid-Non-resident_Macrophage|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

HAS1 SLC11A1 SLC7A7

2.25e-041902834fe9654a9b449ef49ca10b973ac4378dab34cb53
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage_2|343B / Donor, Lineage, Cell class and subclass (all cells)

SLC11A1 SLC2A9 SLC7A7

2.25e-041902836514f00d222eef08c282face7f177259bca62f0e
ToppCellwk_20-22-Hematologic-Myeloid-Neutrophil|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PGA4 SLC11A1 PGA3

2.25e-041902835da4a90f56f66567614d84b9b437f559006ea51c
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC35F2 SLCO1C1 S1PR1

2.32e-041922839ae05db5bfb8b9d3935c0328e6f2d489d2b1ebfd
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC35F2 SLCO1C1 S1PR1

2.32e-04192283a116db7dec495e5a0ba9c7537057cd1e567d7885
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC35F2 SLCO1C1 S1PR1

2.32e-0419228366defad13bd8e79319741e43ddb056841710b1d7
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC35F2 SLCO1C1 S1PR1

2.35e-041932831772f2ac217727de63c4a9303881b3a19a6bb0f0
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)-D122|Adult / Lineage, Cell type, age group and donor

SLC11A1 SLC2A9 SLC7A7

2.35e-04193283cc1b6d3bf56e4a88f6fe23dd036a83cf5538c958
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC35F2 SLCO1C1 S1PR1

2.35e-04193283e4b440d50ae7391b26924778be6d9d53e0692449
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC35F2 SLCO1C1 S1PR1

2.35e-04193283e523dc5751f6fdcd4fc1a62b1eecd43f6ae79da9
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Radial_glial-gliogenic/outer_RGCs_and_astrocytes|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

PAQR6 SLCO1C1 S1PR1

2.39e-041942837c6c0376603e5fcb64814fd6204d153629c2fbf5
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLC11A1 SLC2A9 SLC7A7

2.39e-0419428369cf7c989ac355c459db13f9d4267b55adc3c174
ToppCellmetastatic_Brain-Myeloid_cells-Monocytes|metastatic_Brain / Location, Cell class and cell subclass

HAS1 SLC11A1 SLC7A7

2.42e-04195283dfc24ee09bdc20d8a38feb8a4cc5f6b54a032981
ToppCellImmune-alveolar_macrophage_(MARCO_positive)|World / Lineage, Cell type, age group and donor

SLC11A1 SLC2A9 SLC7A7

2.42e-04195283f92114ef995e690a3bedc62c89c5fd6773d0d9f7
ToppCellwk_15-18-Hematologic-Myeloid-Neutrophil|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PGA4 SLC11A1 PGA5

2.46e-0419628336c01e0feea33448222010c21442b9fac671bd7d
ToppCellproximal-Hematologic-Nonclassical_Monocyte-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SLC11A1 SLC7A7 PGA5

2.46e-041962837e136975e5943d42d51d8cc91c912547ef79cf4d
ToppCellproximal-3-Hematologic-Nonclassical_Monocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SLC11A1 SLC7A7 PGA5

2.46e-04196283e426d02c6bcff2358a45e627cc86389070a4af25
ToppCellproximal-Hematologic-Nonclassical_Monocyte|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SLC11A1 SLC7A7 PGA5

2.46e-04196283439d695526714772971fd1a4a92b8b6a84eee1a4
ToppCell10x5'v1-week_12-13-Myeloid_neutrophil-granulo-neutrophil-neutrophil|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SLC11A1 SLC7A7 PGA3

2.50e-041972838dd10962b6ba587512b2e68c762ade68c751cbc8
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW19-Macroglial-Astrocyte|GW19 / Sample Type, Dataset, Time_group, and Cell type.

PAQR6 SLCO1C1 S1PR1

2.54e-04198283bfad1c51cf884ff7ce89f8278820800582541dc7
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLC11A1 SLC2A9 SLC7A7

2.54e-04198283e125eb8aa57c172e5518874da1bd25998292f5e2
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLC11A1 SLC2A9 SLC7A7

2.54e-041982836a4161680b46b2c12353a693c403b5a4bb3da03f
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLC11A1 SLC2A9 SLC7A7

2.54e-041982830baeb8e2c199ff10bb5c829c523546af3c9227c1
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLC11A1 SLC2A9 SLC7A7

2.54e-041982830b41b3d6c2db795320e8b65d40d85fb8b618cc34
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW19-Macroglial|GW19 / Sample Type, Dataset, Time_group, and Cell type.

PAQR6 SLCO1C1 S1PR1

2.54e-041982836372e65242236c497d9b3be147092897c1609d22
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-IN_Progenitors|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

PAQR6 SLCO1C1 S1PR1

2.54e-041982833811d9e3e54bbe8b208c591697e43b55ab5bbf0e
ToppCellBronchus_Control_(B.)-Immune-TX-MoAM-3|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

SLC11A1 SLC7A7 PGA5

2.54e-041982831d92b09aeb03a95fa9e221813002045c4f41dd24
ToppCellfacs-Tongue-nan-3m-Epithelial-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM30B HUWE1 DDB1

2.57e-041992838d50e1ee58710d896c0204937331d9f4dcd38de0
ToppCell10x3'2.3-week_12-13-Myeloid_neutrophil-granulo-neutrophil-neutrophil|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SLC11A1 SLC7A7 PGA5

2.57e-041992837cbd98dd10c91584dee04593910031e90c1340b8
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW23-Myeloid-Microglia|GW23 / Sample Type, Dataset, Time_group, and Cell type.

SLC11A1 SLC7A7 PIEZO1

2.57e-041992834ddfbcaa8054b69b3398d8c0d5fab8ae94805cb9
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Monocytic-Monocyte_CD16|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SLC11A1 SLC7A7 PGA3

2.57e-0419928336662a76211162b1bf2d58dc819cae339f715c5f
ToppCellParenchymal-NucSeq-Immune_Myeloid|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLC11A1 SLC2A9 SLC7A7

2.57e-041992837ee2805fd9143eba11bf6832267b62189683608b
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW23-Myeloid|GW23 / Sample Type, Dataset, Time_group, and Cell type.

SLC11A1 SLC7A7 PIEZO1

2.57e-041992833ba48a4715d5e9387650aa97e0c5d7f7897bf380
ToppCellControl_saline-Hematopoietic_Myeloid-Granulocytic_cells-Mast-cells|Control_saline / Treatment groups by lineage, cell group, cell type

PAQR6 HHIPL1 HAS1

2.61e-0420028358b25dc2d29e98354bfc8e8e161796c237c3dc23
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Macroglial-Glia_progenitor_cell|GW23 / Sample Type, Dataset, Time_group, and Cell type.

UBIAD1 SLCO1C1 S1PR1

2.61e-04200283859f98f63797087e7df18be632de153009b6cab1
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Mesenchymal|GW23 / Sample Type, Dataset, Time_group, and Cell type.

SLC11A1 SLC7A7 PIEZO1

2.61e-042002830eccf41edefc3b8b5d0316f57d5ba572949aec2b
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Mesenchymal-BMP_responsible_cell|GW23 / Sample Type, Dataset, Time_group, and Cell type.

SLC11A1 SLC7A7 PIEZO1

2.61e-0420028301d707c4f8ee0daac635b7260937b1baebc6fc23
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Macroglial-Astrocyte|6m / Sample Type, Dataset, Time_group, and Cell type.

PAQR6 SLCO1C1 S1PR1

2.61e-042002836ff22adb3007c3c9ef64a05c9dbc1d440bdaee1b
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Macroglial|GW19 / Sample Type, Dataset, Time_group, and Cell type.

PAQR6 SLCO1C1 S1PR1

2.61e-042002833a954d9d542e52c9b181f0850a09b1bff0a0c82d
ToppCellBronchial-NucSeq-Immune_Myeloid|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLC11A1 SLC2A9 SLC7A7

2.61e-042002832f5b71e55c2de0e77fdae6667eb57f333acc6cd1
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLC11A1 SLC2A9 SLC7A7

2.61e-04200283a443e475e7a10c26a6173d1af961de6219e0e567
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Macroglial-Astrocyte|GW19 / Sample Type, Dataset, Time_group, and Cell type.

PAQR6 SLCO1C1 S1PR1

2.61e-042002837c66953ff6d8f16f4decd23c85232990d2d8c6c4
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLC11A1 SLC2A9 SLC7A7

2.61e-04200283ed785a6d08ca2b350dc3307b587eadfb2886d1f9
ToppCellTracheal-10x3prime_v2-Immune_Myeloid-Monocytic-Monocyte_CD16|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SLC11A1 SLC7A7 PGA5

2.61e-0420028394d7aa057a31287696a634d15ce91ce64af6455b
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Macroglial|6m / Sample Type, Dataset, Time_group, and Cell type.

PAQR6 SLCO1C1 S1PR1

2.61e-0420028342dc8ed66a021097e703eef2d756607396ca2f56
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Sla_(Layer6a)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TAS1R2 PGA5

4.86e-0452282c134eb63bd1969af2af7f8de5989e19063533865
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Sla_(Layer6a)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TAS1R2 PGA5

4.86e-045228214971277db09343d668e4f5a82ca2b6a92326251
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Adora2a_(Striatum,_iSPNs)--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TMEM30B SLC45A2

6.25e-0459282a8c9a99501dc244471362915dd847ab2c6e164bf
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Adora2a_(Striatum,_iSPNs)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TMEM30B SLC45A2

6.25e-0459282469e47aa60bf7072e80db15e51da4c103b2a21ff
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Adora2a_(Striatum,_iSPNs)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TMEM30B SLC45A2

6.25e-04592824f9f20aa4d5ad91c01ef7e9d60b59b5bade6a399
ToppCellHippocampus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Fabp7_(Fabp7)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

PAQR6 HHIPL1

1.03e-037628227fa0c5e95d29753875f1c5b04243dc6c6891ee1
ToppCellHippocampus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Fabp7_(Fabp7)|Hippocampus / BrainAtlas - Mouse McCarroll V32

PAQR6 HHIPL1

1.03e-0376282269921aac79ffd2cf680f76fda15baeafb7c1ba9
ToppCellHippocampus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Fabp7_(Fabp7)--|Hippocampus / BrainAtlas - Mouse McCarroll V32

PAQR6 HHIPL1

1.03e-03762823fac82dea7307808c8dbb7acfba707f16b312104
ToppCellASK452-Epithelial-Type_2|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

POMT2 SLC2A9

1.29e-0385282523a532e91aa271faab67d0256919b67af2bd7d8
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_1|Entopeduncular / BrainAtlas - Mouse McCarroll V32

SLC45A2 SLC7A7

1.85e-031022822c3622fc3cd62d9b7e185d0204cf7f03e7dde73c
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SLC45A2 POPDC3

1.92e-03104282b5ca6e589f414e549f4990fe334d4ee54829b298
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2-Endothelial_Tip.Dcn.Ifitm1_(Ifitm1)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

TMEM30B HHIPL1

2.07e-031082822a00a9d3c9ef0c9c743939ee6e79ccbd401eccf7
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2-Endothelial_Tip.Dcn.Ifitm1_(Ifitm1)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

TMEM30B HHIPL1

2.07e-03108282db82e0273ce10627462ff0402f4c1d4c9cb3875b
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

TMEM30B HHIPL1

2.07e-031082820c8bac6c520a3600765327c44705675927bc2f60
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_1|Thalamus / BrainAtlas - Mouse McCarroll V32

SLC35F2 SLCO1C1

2.11e-031092824e4a884b8979f4ff8b232c1581ea78884dda29ed
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-Like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TAS1R2 TMEM30B

2.15e-03110282c80d1c3df75648e2c8f6832279c2acca63d76681
ToppCellLPS_only-Unknown|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

POPDC3 SLCO1C1

2.34e-031152827a733f6987b40ec497a03734b79ed5355ad3a2fc
ToppCellLPS_only-Unknown-Endothelial-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

POPDC3 SLCO1C1

2.34e-03115282c67145d3cd9243994a141749b426ff2a6dcc8d93
ToppCellLPS_only-Unknown-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

POPDC3 SLCO1C1

2.34e-03115282ad5298c2ad8bf94fa13c2e50b0799e929473ef59
ToppCellLPS-IL1RA-Endothelial-Epi-like|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC45A1 HAS1

2.38e-03116282cf4e3c34570f57502ec524881d351ef8e47976d2
ToppCellHippocampus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Nnat_(Nnat)|Hippocampus / BrainAtlas - Mouse McCarroll V32

PAQR6 S1PR1

2.59e-031212828334a6b2ced1d6a4808458d6d4232d1b688ba28a
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Pax6|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC35F2 POPDC3

2.59e-031212827f2057367777c6c92f596054cbc5fe567d079fbc
ToppCellHippocampus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Nnat_(Nnat)--|Hippocampus / BrainAtlas - Mouse McCarroll V32

PAQR6 S1PR1

2.59e-031212824b33eeed7b70da120133b14d42c104d2461d52dc
ToppCellHippocampus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Nnat_(Nnat)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

PAQR6 S1PR1

2.59e-03121282a33e4ae0b0efb702db1b646ac0486e3b6ce48457
ToppCellTCGA-Head_and_Esophagus-Solid_Tissue_Normal-Esophagus_normal_tissue-Esophagus_normal_tissue|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

PGA4 PGA5

2.63e-031222824f091144530ac1e85f7a8296847ec08753156d71
ToppCellTCGA-Head_and_Esophagus-Solid_Tissue_Normal-Esophagus_normal_tissue|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

PGA4 PGA5

2.63e-031222829f48ba786d913182021b3e42349fb84934b855b8
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_B|PND01-03-samps / Age Group, Lineage, Cell class and subclass

SLCO1C1 S1PR1

2.67e-03123282e0130010aa406d4e9d8f16ad32858c382277eeb2
ToppCellPosterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Acta2Rgs5.Abcc9_(Mural.Acta2Rgs5.Abcc9)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TMEM30B SLC11A1

2.80e-0312628243e7b226a195ab2068518b3a9ffd2192129e8ae4
ToppCellPosterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Acta2Rgs5.Abcc9_(Mural.Acta2Rgs5.Abcc9)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TMEM30B SLC11A1

2.80e-031262822b06adfb00a557bd90ad93719548a49f9ae9edeb
ToppCellLPS-IL1RA-Endothelial-Epi-like-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC45A1 HAS1

2.85e-031272826b24630978eb0772b4cd3bf59e5bc4390be47619
ToppCellTCGA-Mesothelium|World / Sample_Type by Project: Shred V9

HHIPL1 HAS1

2.98e-031302823ef1733eb57e2a9a3298ce0d65401f19e2084df1
ToppCellTCGA-Head_and_Esophagus-Solid_Tissue_Normal-Esophagus_normal_tissue-Esophagus_normal_tissue-2|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

PGA4 PGA5

2.98e-031302823450b9edc7360f8494b5e2ded3132c508bbc971b
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

TMEM30B HHIPL1

3.07e-03132282893b7ec2a2d8a140cc98575d1beca1189f053e9a
Drugfenuron

HAS1 SLC7A7 PGA5

4.72e-0713283CID000007560
DrugDantrolene sodium salt [14663-23-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A

POMT2 SLC45A2 POPDC3 PAQR6 SLC11A1

4.05e-061992852329_UP
Drug2e A

SLC45A2 SLC7A7

3.05e-057282CID011840906
Drugretinoic acid; Down 200; 1uM; HL60; HT_HG-U133A

SLC35F2 UBIAD1 SLC2A9 PIEZO1

6.67e-051802841152_DN
DrugEthotoin [86-35-1]; Up 200; 19.6uM; MCF7; HT_HG-U133A

POPDC3 HUWE1 SLC7A7 RHAG

8.91e-051942844366_UP
DrugPipenzolate bromide [125-51-9]; Up 200; 9.2uM; PC3; HT_HG-U133A

SLC45A2 HUWE1 SLC11A1 SLCO1C1

9.28e-051962844484_UP
DrugThiamine hydrochloride [67-03-8]; Up 200; 11.8uM; MCF7; HT_HG-U133A

POMT2 PAQR6 SLC11A1 SLC2A9

9.28e-051962847479_UP
DrugAdrenosterone [382-45-6]; Up 200; 13.4uM; PC3; HT_HG-U133A

POMT2 HUWE1 SLC11A1 SLC2A9

9.46e-051972845045_UP
DrugEstriol [50-27-1]; Up 200; 13.8uM; PC3; HT_HG-U133A

POMT2 HUWE1 SLC11A1 RHAG

9.46e-051972845866_UP
DrugDacarbazine [4342-03-4]; Up 200; 22uM; PC3; HT_HG-U133A

SLC45A2 HUWE1 DNAJC22 SLCO1C1

9.46e-051972844480_UP
Drug2-Aminobenzenesulfonamide [3306-62-5]; Up 200; 23.2uM; MCF7; HT_HG-U133A

POMT2 POPDC3 SLC11A1 SLCO1C1

9.65e-051982845422_UP
DrugTolfenamic acid [13710-19-5]; Up 200; 15.2uM; PC3; HT_HG-U133A

HUWE1 SLC2A9 S1PR1 RHAG

9.65e-051982846354_UP
DrugAcetopromazine maleate salt [3598-37-6]; Up 200; 9uM; MCF7; HT_HG-U133A

POPDC3 DNAJC22 SLCO1C1 SLC22A17

1.00e-042002842769_UP
Drugbenzyloxyresorufin

SLC45A2 HAS1 PTCHD3

1.19e-0478283CID000114982
DiseaseStomatocytosis Result

PIEZO1 RHAG

2.24e-063262C0677598
Diseasestomatocytic anemia

PIEZO1 RHAG

2.24e-063262C0272048
Diseaseautosomal recessive limb-girdle muscular dystrophy (is_implicated_in)

POMT2 POPDC3

7.45e-065262DOID:0110274 (is_implicated_in)
Diseasedepressive symptom measurement, response to antidepressant

PIEZO1 RHAG

2.73e-0388262EFO_0007006, GO_0036276

Protein segments in the cluster

PeptideGeneStartEntry
GSFLYYAPFDGILGL

PGA5

171

P0DJD9
SFSLYGNKCYLFGGL

HCFC2

131

Q9Y5Z7
GQLLFGDDGYLYIFT

HHIPL1

316

Q96JK4
YFGLAALLAAAYLGL

SLC11A1

496

P49279
GALSLYSLGCAFPYA

PAQR6

121

Q6TCH4
LFSFLYHLASYDAGG

HUWE1

386

Q7Z6Z7
GSFLYYAPFDGILGL

PGA3

171

P0DJD8
CAGLAFIGLGLGLYY

TMEM30B

41

Q3MIR4
LASDRYGLLAFGLYG

HAS1

46

Q92839
YGLLAFGLYGAFLSA

HAS1

51

Q92839
LAGAFGSSFLYGYNL

SLC2A9

61

Q9NRM0
AGILGLTGLYGFIFY

EMC6

41

Q9BV81
GLAYLAFTGPLAYSA

DNAJC22

186

Q8N4W6
YYFIGNLALSDLLAG

S1PR1

81

P21453
YFIAYLAFGLGTGLA

SLC45A1

641

Q9Y2W3
GLKGLYFTGYLLFGL

SLC45A2

396

Q9UMX9
YFTGYLLFGLGTGFI

SLC45A2

401

Q9UMX9
GFFGLLYVFSLLGLG

POPDC3

46

Q9HBV1
YLLCALGDGALFYFG

DDB1

601

Q16531
YLTGFFGGYILGGSL

PTCHD3

296

Q3KNS1
GSFLYYAPFDGILGL

PGA4

171

P0DJD7
LAGYLSGYDGTFLFQ

POMT2

116

Q9UKY4
LFILGFASGYLFLGY

SLC22A17

106

Q8WUG5
GLFLFGYKFSGLYIL

SLC35F2

306

Q8IXU6
GASYAYILEAFGGFL

SLC7A7

101

Q9UM01
KLYLGSSVFGYLLFL

SLCO1C1

426

Q9NYB5
AFGAYFGLAVAGILY

RHAG

176

Q02094
ALIYFGGLSGSFLYT

UBIAD1

161

Q9Y5Z9
DFYLPGDYLLGGLFS

TAS1R2

26

Q8TE23
GLGYLLACFYLLLFG

PIEZO1

1186

Q92508