Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix structural constituent

COL4A4 COL12A1 CRELD2 SLIT2 FBLN2 FBN1 FBN2 HMCN2 VCAN COL14A1 MUC4 FBN3

1.96e-1018810112GO:0005201
GeneOntologyMolecularFunctionalpha1-adrenergic receptor activity

ADRA1D ADRA1B ADRA1A

1.26e-0731013GO:0004937
GeneOntologyMolecularFunctioncalcium ion binding

NOTCH2NLA CRELD2 PLA2G2F ADGRE2 DLL1 NOTCH2NLC SVEP1 SLIT2 FBLN2 FBN1 FBN2 HMCN2 EGF ADGRE3 VCAN FBN3 NOTCH2

2.02e-0774910117GO:0005509
GeneOntologyMolecularFunctionalpha-adrenergic receptor activity

ADRA1D ADRA1B ADRA1A

2.48e-0661013GO:0004936
GeneOntologyMolecularFunctionadrenergic receptor activity

ADRA1D ADRA1B ADRA1A

1.47e-05101013GO:0004935
GeneOntologyMolecularFunctionextracellular matrix constituent conferring elasticity

FBLN2 FBN1 FBN2

2.67e-05121013GO:0030023
GeneOntologyMolecularFunctionstructural molecule activity conferring elasticity

FBLN2 FBN1 FBN2

4.39e-05141013GO:0097493
GeneOntologyMolecularFunctionstructural molecule activity

COL4A4 COL12A1 CRELD2 SLIT2 CRYGB FBLN2 FBN1 FBN2 HMCN2 VCAN COL14A1 KRTAP24-1 MUC4 FBN3

1.55e-0489110114GO:0005198
GeneOntologyMolecularFunctionextracellular matrix binding

ZAN SLIT2 FBLN2 LYPD3

5.14e-04731014GO:0050840
GeneOntologyMolecularFunctionG protein-coupled amine receptor activity

ADRA1D ADRA1B ADRA1A

1.16e-03411013GO:0008227
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

TRPV1 CHRNA9 OR4E2 ADGRE2 PLXNB2 ADRA1D ADRA1B ADRA1A HMCN2 EDAR ADGRE3 SEMA6A CHRNA10 ADGRL2 NOTCH2 SORL1

1.21e-03135310116GO:0004888
GeneOntologyMolecularFunctionexcitatory extracellular ligand-gated monoatomic ion channel activity

TRPV1 CHRNA9 CHRNA10

1.34e-03431013GO:0005231
GeneOntologyMolecularFunctionRoundabout binding

SLIT2 IGFALS

1.62e-03121012GO:0048495
GeneOntologyMolecularFunctionextracellular matrix structural constituent conferring tensile strength

COL4A4 COL12A1 COL14A1

1.63e-03461013GO:0030020
GeneOntologyBiologicalProcessneuron-glial cell signaling

ADRA1D ADRA1B ADRA1A

1.20e-0651033GO:0150099
GeneOntologyBiologicalProcessregulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback

ADRA1D ADRA1B ADRA1A

2.39e-0661033GO:0001978
GeneOntologyBiologicalProcesspositive regulation of blood pressure by epinephrine-norepinephrine

ADRA1D ADRA1B ADRA1A

4.17e-0671033GO:0003321
GeneOntologyBiologicalProcessregulation of systemic arterial blood pressure by norepinephrine-epinephrine

ADRA1D ADRA1B ADRA1A

6.65e-0681033GO:0001993
GeneOntologyBiologicalProcessregulation of systemic arterial blood pressure by baroreceptor feedback

ADRA1D ADRA1B ADRA1A

6.65e-0681033GO:0003025
GeneOntologyBiologicalProcessregulation of protein localization to early endosome

DTX3L EGF SORL1

1.41e-05101033GO:1902965
GeneOntologyBiologicalProcesspositive regulation of protein localization to early endosome

DTX3L EGF SORL1

1.41e-05101033GO:1902966
GeneOntologyBiologicalProcessregulation of cellular response to growth factor stimulus

ELAPOR2 ZEB1 ZNF423 DLL1 SLIT2 FBN1 FBN2 SEMA6A NOTCH2 SORL1

4.10e-0541210310GO:0090287
GeneOntologyBiologicalProcesspositive regulation of protein localization to endosome

DTX3L EGF SORL1

4.23e-05141033GO:1905668
GeneOntologyBiologicalProcesspositive regulation of neural precursor cell proliferation

FLNA INSM1 EGF VCAN NOTCH2

5.03e-05801035GO:2000179
GeneOntologyBiologicalProcessregulation of protein localization to endosome

DTX3L EGF SORL1

5.27e-05151033GO:1905666
GeneOntologyBiologicalProcessprotein localization to early endosome

DTX3L EGF SORL1

6.46e-05161033GO:1902946
GeneOntologyBiologicalProcessnorepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure

ADRA1D ADRA1A

7.38e-0531032GO:0001994
GeneOntologyBiologicalProcessbaroreceptor response to increased systemic arterial blood pressure

ADRA1D ADRA1A

7.38e-0531032GO:0001983
GeneOntologyBiologicalProcessNotch signaling pathway

ZNF423 NOTCH2NLA DTX3L DLL1 NOTCH2NLC TP63 NOTCH2

8.90e-052101037GO:0007219
GeneOntologyBiologicalProcesspositive regulation of cytosolic calcium ion concentration

TRPV1 CHRNA9 ADRA1D ADRA1B ADRA1A CHRNA10 OGA

1.33e-042241037GO:0007204
GeneOntologyBiologicalProcesspositive regulation of Notch signaling pathway

NOTCH2NLA DLL1 NOTCH2NLC TP63

1.42e-04531034GO:0045747
GeneOntologyBiologicalProcesssequestering of TGFbeta in extracellular matrix

FBN1 FBN2

1.47e-0441032GO:0035583
GeneOntologyBiologicalProcesspositive regulation of heart rate by epinephrine-norepinephrine

ADRA1B ADRA1A

1.47e-0441032GO:0001996
GeneOntologyBiologicalProcesspositive regulation of the force of heart contraction by epinephrine-norepinephrine

ADRA1B ADRA1A

1.47e-0441032GO:0001997
GeneOntologyBiologicalProcessneural precursor cell proliferation

FLNA ZNF423 INSM1 PLXNB2 EGF VCAN NOTCH2

1.69e-042331037GO:0061351
GeneOntologyBiologicalProcessnervous system process involved in regulation of systemic arterial blood pressure

ADRA1D ADRA1B ADRA1A

2.27e-04241033GO:0001976
GeneOntologyBiologicalProcesspositive regulation of the force of heart contraction by chemical signal

ADRA1B ADRA1A

2.45e-0451032GO:0003099
GeneOntologyBiologicalProcessadenylate cyclase-activating adrenergic receptor signaling pathway

ADRA1D ADRA1B ADRA1A

2.57e-04251033GO:0071880
GeneOntologyBiologicalProcessadenylate cyclase-activating G protein-coupled receptor signaling pathway

ADGRE2 ADRA1D ADRA1B ADRA1A ADGRE3 ADGRL2

3.96e-041911036GO:0007189
GeneOntologyBiologicalProcessepithelial cell development

FLNA INSM1 DLL1 CRYGB FASN TP63 NOTCH2

4.05e-042691037GO:0002064
GeneOntologyBiologicalProcessnegative regulation of heart contraction

TRPV1 ADRA1D ADRA1A

4.45e-04301033GO:0045822
GeneOntologyBiologicalProcessregulation of BMP signaling pathway

ELAPOR2 ZNF423 FBN1 NOTCH2 SORL1

5.09e-041311035GO:0030510
GeneOntologyBiologicalProcessnegative regulation of blood circulation

TRPV1 ADRA1D ADRA1A

5.40e-04321033GO:1903523
GeneOntologyBiologicalProcessnegative regulation of systemic arterial blood pressure

TRPV1 ADRA1D ADRA1A

5.40e-04321033GO:0003085
GeneOntologyBiologicalProcessadenylate cyclase-modulating G protein-coupled receptor signaling pathway

FLNA ADGRE2 ADRA1D ADRA1B ADRA1A ADGRE3 ADGRL2

5.84e-042861037GO:0007188
GeneOntologyBiologicalProcessregulation of neural precursor cell proliferation

FLNA INSM1 EGF VCAN NOTCH2

5.84e-041351035GO:2000177
GeneOntologyBiologicalProcessprotein localization to endosome

DTX3L EGF SORL1

5.92e-04331033GO:0036010
GeneOntologyBiologicalProcessmaintenance of protein location in extracellular region

FBN1 FBN2

6.78e-0481032GO:0071694
GeneOntologyBiologicalProcessregulation of the force of heart contraction by chemical signal

ADRA1B ADRA1A

6.78e-0481032GO:0003057
GeneOntologyBiologicalProcessadrenergic receptor signaling pathway

ADRA1D ADRA1B ADRA1A

7.05e-04351033GO:0071875
GeneOntologyCellularComponentextracellular matrix

COL4A4 COL12A1 ZAN PLXNB2 SVEP1 SLIT2 FBLN2 FBN1 FBN2 IGFALS HMCN2 VCAN COL14A1 MUC4 FBN3

8.65e-0765610415GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

COL4A4 COL12A1 ZAN PLXNB2 SVEP1 SLIT2 FBLN2 FBN1 FBN2 IGFALS HMCN2 VCAN COL14A1 MUC4 FBN3

8.98e-0765810415GO:0030312
GeneOntologyCellularComponentmicrofibril

FBN1 FBN2 FBN3

3.30e-05131043GO:0001527
GeneOntologyCellularComponentcollagen-containing extracellular matrix

COL4A4 COL12A1 PLXNB2 SLIT2 FBLN2 FBN1 FBN2 HMCN2 VCAN COL14A1 MUC4

6.67e-0553010411GO:0062023
GeneOntologyCellularComponentanchoring collagen complex

COL12A1 COL14A1

7.33e-0531042GO:0030934
GeneOntologyCellularComponentRAVE complex

DMXL2 DMXL1

7.33e-0531042GO:0043291
GeneOntologyCellularComponentFACIT collagen trimer

COL12A1 COL14A1

3.63e-0461042GO:0005593
GeneOntologyCellularComponentkeratin filament

KRTAP9-4 KRTAP9-2 KRTAP9-9 KRTAP24-1

1.41e-03971044GO:0045095
DomainEGF_Ca-bd_CS

NOTCH2NLA CRELD2 ADGRE2 DLL1 NOTCH2NLC SVEP1 SLIT2 FBLN2 FBN1 FBN2 HMCN2 EGF ADGRE3 VCAN FBN3 NOTCH2

8.60e-209710116IPR018097
DomainEGF_CA

NOTCH2NLA CRELD2 ADGRE2 DLL1 NOTCH2NLC SVEP1 SLIT2 FBLN2 FBN1 FBN2 HMCN2 EGF ADGRE3 VCAN FBN3 NOTCH2

1.22e-199910116PS01187
DomainASX_HYDROXYL

NOTCH2NLA CRELD2 ADGRE2 DLL1 NOTCH2NLC SVEP1 SLIT2 FBLN2 FBN1 FBN2 HMCN2 EGF ADGRE3 VCAN FBN3 NOTCH2

1.44e-1910010116PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

NOTCH2NLA CRELD2 ADGRE2 DLL1 NOTCH2NLC SVEP1 SLIT2 FBLN2 FBN1 FBN2 HMCN2 EGF ADGRE3 VCAN FBN3 NOTCH2

3.85e-1910610116IPR000152
DomainEGF_3

ZAN NOTCH2NLA CRELD2 ADGRE2 DLL1 NOTCH2NLC PGAP6 SVEP1 SLIT2 FBLN2 FBN1 FBN2 HMCN2 EGF ADGRE3 VCAN MUC4 FBN3 NOTCH2 SORL1

1.19e-1823510120PS50026
DomainEGF

ZAN NOTCH2NLA CRELD2 ADGRE2 DLL1 NOTCH2NLC PGAP6 SVEP1 RSPO3 SLIT2 FBLN2 FBN1 FBN2 EGF ADGRE3 VCAN MUC4 FBN3 NOTCH2 SORL1

1.19e-1823510120SM00181
DomainEGF-like_dom

ZAN NOTCH2NLA CRELD2 ADGRE2 DLL1 NOTCH2NLC PGAP6 SVEP1 SLIT2 FBLN2 FBN1 FBN2 HMCN2 EGF ADGRE3 VCAN MUC4 FBN3 NOTCH2 SORL1

3.74e-1824910120IPR000742
DomainEGF_CA

NOTCH2NLA CRELD2 ADGRE2 DLL1 NOTCH2NLC SVEP1 SLIT2 FBLN2 FBN1 FBN2 HMCN2 EGF ADGRE3 VCAN FBN3 NOTCH2

4.01e-1812210116SM00179
DomainEGF-like_Ca-bd_dom

NOTCH2NLA CRELD2 ADGRE2 DLL1 NOTCH2NLC SVEP1 SLIT2 FBLN2 FBN1 FBN2 HMCN2 EGF ADGRE3 VCAN FBN3 NOTCH2

5.24e-1812410116IPR001881
DomainEGF-like_CS

ZAN NOTCH2NLA CRELD2 ADGRE2 DLL1 NOTCH2NLC PGAP6 SVEP1 SLIT2 FBLN2 FBN1 FBN2 HMCN2 EGF VCAN MUC4 FBN3 NOTCH2 SORL1

1.75e-1626110119IPR013032
DomainEGF_2

ZAN NOTCH2NLA CRELD2 ADGRE2 DLL1 NOTCH2NLC PGAP6 SVEP1 SLIT2 FBLN2 FBN1 FBN2 HMCN2 EGF VCAN MUC4 FBN3 NOTCH2 SORL1

2.33e-1626510119PS01186
DomainEGF_CA

NOTCH2NLA CRELD2 ADGRE2 NOTCH2NLC SVEP1 FBLN2 FBN1 FBN2 HMCN2 EGF ADGRE3 FBN3 NOTCH2

9.58e-168610113PF07645
DomainEGF_1

ZAN NOTCH2NLA CRELD2 ADGRE2 DLL1 NOTCH2NLC PGAP6 SVEP1 SLIT2 FBLN2 FBN1 FBN2 HMCN2 EGF VCAN MUC4 FBN3 NOTCH2

2.02e-1525510118PS00022
DomainGrowth_fac_rcpt_

ELAPOR2 CRELD2 ADGRE2 DLL1 SVEP1 RSPO3 FBLN2 FBN1 FBN2 HMCN2 EGF ADGRE3 ELAPOR1 FBN3 NOTCH2

5.44e-1515610115IPR009030
DomainEGF

ZAN NOTCH2NLA DLL1 NOTCH2NLC SVEP1 SLIT2 EGF VCAN MUC4 FBN3 NOTCH2

8.05e-1112610111PF00008
DomainhEGF

DLL1 SVEP1 SLIT2 FBN2 FBN3 NOTCH2

7.36e-09281016PF12661
DomainFBN

FBN1 FBN2 FBN3

1.53e-0731013IPR011398
DomainTB

FBN1 FBN2 FBN3

5.29e-0671013PF00683
Domain-

FBN1 FBN2 FBN3

8.43e-06810133.90.290.10
DomaincEGF

FBLN2 FBN1 FBN2 FBN3

1.10e-05261014IPR026823
DomaincEGF

FBLN2 FBN1 FBN2 FBN3

1.10e-05261014PF12662
DomainTB

FBN1 FBN2 FBN3

1.26e-0591013PS51364
DomainTB_dom

FBN1 FBN2 FBN3

1.26e-0591013IPR017878
Domain-

DMXL2 DYNC2I2 BCAS3 PLXNB2 DDB1 DMXL1 TULP4 SEMA6A WDR90 BRWD1

1.30e-05333101102.130.10.10
DomainWD40/YVTN_repeat-like_dom

DMXL2 DYNC2I2 BCAS3 PLXNB2 DDB1 DMXL1 TULP4 SEMA6A WDR90 BRWD1

1.37e-0533510110IPR015943
DomainADR_fam

ADRA1D ADRA1B ADRA1A

1.79e-05101013IPR002233
DomainRav1p_C

DMXL2 DMXL1

2.90e-0521012IPR022033
DomainRav1p_C

DMXL2 DMXL1

2.90e-0521012PF12234
DomainAMOP

ISM1 MUC4

1.73e-0441012SM00723
DomainAMOP

ISM1 MUC4

1.73e-0441012PF03782
DomainAMOP_dom

ISM1 MUC4

1.73e-0441012IPR005533
DomainAMOP

ISM1 MUC4

1.73e-0441012PS50856
DomainWD40_repeat_dom

DMXL2 DYNC2I2 BCAS3 DDB1 DMXL1 TULP4 WDR90 BRWD1

2.09e-042971018IPR017986
DomainEphrin_rec_like

ELAPOR2 SVEP1 ELAPOR1

3.24e-04251013SM01411
DomainTyr-kin_ephrin_A/B_rcpt-like

ELAPOR2 SVEP1 ELAPOR1

3.24e-04251013IPR011641
DomainWD40

DMXL2 DYNC2I2 BCAS3 DMXL1 TULP4 WDR90 BRWD1

5.16e-042591017PF00400
DomainWD40

DMXL2 DYNC2I2 BCAS3 DMXL1 TULP4 WDR90 BRWD1

6.32e-042681017SM00320
DomainWD40_repeat

DMXL2 DYNC2I2 BCAS3 DMXL1 TULP4 WDR90 BRWD1

6.90e-042721017IPR001680
DomainWD_REPEATS_1

DMXL2 DYNC2I2 BCAS3 DMXL1 TULP4 WDR90 BRWD1

7.84e-042781017PS00678
DomainMan6P_isomerase_rcpt-bd_dom

ELAPOR2 ELAPOR1

7.94e-0481012IPR009011
DomainWD_REPEATS_2

DMXL2 DYNC2I2 BCAS3 DMXL1 TULP4 WDR90 BRWD1

8.01e-042791017PS50082
DomainWD_REPEATS_REGION

DMXL2 DYNC2I2 BCAS3 DMXL1 TULP4 WDR90 BRWD1

8.01e-042791017PS50294
DomainGPS

ADGRE2 ADGRE3 ADGRL2

8.13e-04341013SM00303
DomainGPCR_2_secretin-like_CS

ADGRE2 ADGRE3 ADGRL2

8.13e-04341013IPR017983
DomainGPS

ADGRE2 ADGRE3 ADGRL2

8.86e-04351013PF01825
DomainGPS

ADGRE2 ADGRE3 ADGRL2

9.63e-04361013PS50221
DomainVWFA

COL12A1 SVEP1 HMCN2 COL14A1

1.02e-03821014PS50234
DomainGPS

ADGRE2 ADGRE3 ADGRL2

1.04e-03371013IPR000203
DomainVWA

COL12A1 SVEP1 HMCN2 COL14A1

1.12e-03841014SM00327
DomainKeratin_B2_2

KRTAP9-4 KRTAP9-2 KRTAP9-9

1.22e-03391013PF13885
DomainKeratin_B2

KRTAP9-4 KRTAP9-2 KRTAP9-9

1.31e-03401013PF01500
Domain-

SVEP1 EGF

1.54e-031110122.40.155.10
DomainGFP-like

SVEP1 EGF

1.54e-03111012IPR023413
DomainGAIN_dom_N

ADGRE3 ADGRL2

1.54e-03111012IPR032471
DomainGAIN

ADGRE3 ADGRL2

1.54e-03111012PF16489
DomainVWF_A

COL12A1 SVEP1 HMCN2 COL14A1

2.05e-03991014IPR002035
DomainPMG

KRTAP13-2 KRTAP24-1

2.17e-03131012PF05287
DomainKRTAP_PMG

KRTAP13-2 KRTAP24-1

2.17e-03131012IPR007951
DomainG_PROTEIN_RECEP_F2_2

ADGRE2 ADGRE3 ADGRL2

2.50e-03501013PS00650
Domain7tm_2

ADGRE2 ADGRE3 ADGRL2

2.50e-03501013PF00002
DomainIMPORTIN_B_NT

TNPO1 TNPO2

2.53e-03141012PS50166
DomainLdl_recept_b

EGF SORL1

2.53e-03141012PF00058
DomainLDLRB

EGF SORL1

2.53e-03141012PS51120
DomainIBN_N

TNPO1 TNPO2

2.90e-03151012PF03810
DomainLY

EGF SORL1

2.90e-03151012SM00135
DomainLDLR_classB_rpt

EGF SORL1

2.90e-03151012IPR000033
DomainVWD

ZAN MUC4

3.31e-03161012SM00216
DomainVWF_type-D

ZAN MUC4

3.31e-03161012IPR001846
DomainIBN_N

TNPO1 TNPO2

3.31e-03161012SM00913
DomainVWFD

ZAN MUC4

3.31e-03161012PS51233
DomainNicotinic_acetylcholine_rcpt

CHRNA9 CHRNA10

3.31e-03161012IPR002394
DomainVWD

ZAN MUC4

3.31e-03161012PF00094
DomainVWA

COL12A1 SVEP1 COL14A1

3.46e-03561013PF00092
DomainImportin-beta_N

TNPO1 TNPO2

3.73e-03171012IPR001494
DomainLaminin_G

COL12A1 SLIT2 COL14A1

3.82e-03581013IPR001791
DomainKAP

KRTAP9-4 KRTAP9-2 KRTAP9-9

3.82e-03581013IPR002494
DomainFurin_repeat

CRELD2 RSPO3

4.19e-03181012IPR006212
DomainFU

CRELD2 RSPO3

4.19e-03181012SM00261
DomainGPCR_2_secretin-like

ADGRE2 ADGRE3 ADGRL2

4.20e-03601013IPR000832
DomainGPCR_2-like

ADGRE2 ADGRE3 ADGRL2

4.20e-03601013IPR017981
DomainG_PROTEIN_RECEP_F2_4

ADGRE2 ADGRE3 ADGRL2

4.40e-03611013PS50261
PathwayWP_HYPOTHESIZED_PATHWAYS_IN_PATHOGENESIS_OF_CARDIOVASCULAR_DISEASE

FLNA FBN1 FBN2 FBN3

7.71e-0625734M39713
PathwayREACTOME_ADRENOCEPTORS

ADRA1D ADRA1B ADRA1A

1.09e-059733M27302
PathwayREACTOME_ADRENOCEPTORS

ADRA1D ADRA1B ADRA1A

1.09e-059733MM15009
PathwayWP_PRIMARY_OVARIAN_INSUFFICIENCY

TMEM150B TSHB FANCA TP63 MCM9 SPIDR NOTCH2

3.18e-05174737M48058
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

FBLN2 FBN1 FBN2 FBN3

3.84e-0537734M27134
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

FBLN2 FBN1 FBN2 FBN3

7.68e-0544734M26969
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

COL4A4 COL12A1 FBN1 FBN2 COL14A1 FBN3

8.49e-05140736M587
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

COL4A4 COL12A1 FBLN2 FBN1 FBN2 VCAN COL14A1 FBN3

1.55e-04300738M610
PathwayREACTOME_ACETYLCHOLINE_INHIBITS_CONTRACTION_OF_OUTER_HAIR_CELLS

CHRNA9 CHRNA10

2.62e-045732M41824
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

COL4A4 COL12A1 FBLN2 FBN1 FBN2 VCAN COL14A1

3.69e-04258737MM14572
PathwayKEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION

TRPV1 CHRNA9 TSHB ADRA1D ADRA1B ADRA1A CHRNA10

5.07e-04272737M13380
PathwayWP_MONOAMINE_GPCRS

ADRA1D ADRA1B ADRA1A

5.40e-0431733MM15871
PathwayKEGG_MEDICUS_ENV_FACTOR_E2_TO_NUCLEAR_INITIATED_ESTROGEN_SIGNALING_PATHWAY

DLL1 EGF

5.46e-047732M47805
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

FBLN2 FBN1 FBN2

5.93e-0432733MM14854
PathwayWP_MONOAMINE_GPCRS

ADRA1D ADRA1B ADRA1A

6.50e-0433733M39585
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

COL4A4 COL12A1 CRELD2 PLXNB2 SLIT2 FBLN2 FBN1 FBN2 HMCN2 COL14A1 MUC4

5.67e-121751041128071719
Pubmed

Gene expressions and mechanical functions of α1-adrenoceptor subtypes in mouse ureter.

ADRA1D ADRA1B ADRA1A

2.60e-083104319259685
Pubmed

Localizations and expressions of alpha-1A, alpha-1B and alpha-1D adrenoceptors in human ureter.

ADRA1D ADRA1B ADRA1A

2.60e-083104317973108
Pubmed

Examination of alpha 1 adrenoceptor subtypes in the human ureter.

ADRA1D ADRA1B ADRA1A

2.60e-083104317681068
Pubmed

Molecular cloning of alpha 1d-adrenergic receptor and tissue distribution of three alpha 1-adrenergic receptor subtypes in mouse.

ADRA1D ADRA1B ADRA1A

2.60e-08310437595531
Pubmed

Alpha 1-adrenergic receptor responses in alpha 1AB-AR knockout mouse hearts suggest the presence of alpha 1D-AR.

ADRA1D ADRA1B ADRA1A

2.60e-083104312595294
Pubmed

Functional role of α1-adrenoceptor subtypes in murine ophthalmic arteries.

ADRA1D ADRA1B ADRA1A

2.60e-083104321613371
Pubmed

Up-regulation of α1-adrenoceptors in burn and keloid scars.

ADRA1D ADRA1B ADRA1A

2.60e-083104329089212
Pubmed

Role of α1-adrenoceptor subtypes on corneal epithelial thickness and cell proliferation in mice.

ADRA1D ADRA1B ADRA1A

2.60e-083104330257104
Pubmed

Differential regulation of the cell cycle by alpha1-adrenergic receptor subtypes.

ADRA1D ADRA1B ADRA1A

2.60e-083104315297446
Pubmed

The alpha 1-adrenergic receptor that mediates smooth muscle contraction in human prostate has the pharmacological properties of the cloned human alpha 1c subtype.

ADRA1D ADRA1B ADRA1A

2.60e-08310438183249
Pubmed

Blockade of both alpha1A- and alpha1B-adrenergic receptor subtype signaling is required to inhibit neointimal formation in the mouse femoral artery.

ADRA1D ADRA1B ADRA1A

2.60e-083104317384126
Pubmed

Role of α₁-adrenoceptor subtypes in pupil dilation studied with gene-targeted mice.

ADRA1D ADRA1B ADRA1A

2.60e-083104325425303
Pubmed

Cloning, expression and characterization of human alpha adrenergic receptors alpha 1a, alpha 1b and alpha 1c.

ADRA1D ADRA1B ADRA1A

2.60e-08310438024574
Pubmed

Alpha1-adrenoceptors are required for normal male sexual function.

ADRA1D ADRA1B ADRA1A

2.60e-083104317603545
Pubmed

The alpha(1B)-adrenergic receptor decreases the inotropic response in the mouse Langendorff heart model.

ADRA1D ADRA1B ADRA1A

2.60e-083104314659805
Pubmed

The presence and distribution of alpha adrenergic receptors in human renal pelvis and calyces.

ADRA1D ADRA1B ADRA1A

2.60e-083104323877383
Pubmed

Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: sequence corrections and direct comparison with other species homologues.

ADRA1D ADRA1B ADRA1A

2.60e-08310437815325
Pubmed

Evidence of alpha1-adrenoceptor functional changes in omental arteries of patients with end-stage renal disease.

ADRA1D ADRA1B ADRA1A

2.60e-083104318257748
Pubmed

Specific interactions between gC1qR and alpha1-adrenoceptor subtypes.

ADRA1D ADRA1B ADRA1A

2.60e-083104314626446
Pubmed

Neuron-glia signaling via alpha(1) adrenoceptor-mediated Ca(2+) release in Bergmann glial cells in situ.

ADRA1D ADRA1B ADRA1A

2.60e-083104310493741
Pubmed

alpha 1-Adrenergic receptor subtypes differentially control the cell cycle of transfected CHO cells through a cAMP-dependent mechanism involving p27Kip1.

ADRA1D ADRA1B ADRA1A

2.60e-083104312409310
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

COL4A4 COL12A1 PLXNB2 FBLN2 FBN1 HMCN2 VCAN COL14A1

4.16e-08167104822159717
Pubmed

Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly.

FBN1 FBN2 FBN3

1.04e-074104325034023
Pubmed

Evolution of Human Brain Size-Associated NOTCH2NL Genes Proceeds toward Reduced Protein Levels.

NOTCH2NLA NOTCH2NLC NOTCH2

1.04e-074104332330268
Pubmed

Characterization of heteromeric complexes between chemokine (C-X-C motif) receptor 4 and α1-adrenergic receptors utilizing intermolecular bioluminescence resonance energy transfer assays.

ADRA1D ADRA1B ADRA1A

1.04e-074104332085899
Pubmed

Comprehensive proteomic characterization of stem cell-derived extracellular matrices.

COL12A1 FBLN2 FBN1 FBN2 VCAN COL14A1

2.39e-0786104628327460
Pubmed

The stimulatory effects of alpha1-adrenergic receptors on TGF-beta1, IGF-1 and hyaluronan production in human skin fibroblasts.

ADRA1D ADRA1B ADRA1A

2.59e-075104324844469
Pubmed

Human-Specific NOTCH2NL Genes Affect Notch Signaling and Cortical Neurogenesis.

NOTCH2NLA NOTCH2NLC NOTCH2

2.59e-075104329856954
Pubmed

Human-Specific NOTCH2NL Genes Expand Cortical Neurogenesis through Delta/Notch Regulation.

NOTCH2NLA DLL1 NOTCH2NLC

2.59e-075104329856955
Pubmed

Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.

COL12A1 FBLN2 FBN1 FBN2 VCAN

4.13e-0750104523658023
Pubmed

Interaction of neuronal nitric oxide synthase with alpha1-adrenergic receptor subtypes in transfected HEK-293 cells.

ADRA1D ADRA1B ADRA1A

5.16e-076104312184796
Pubmed

Yeast two-hybrid screening for proteins that interact with alpha1-adrenergic receptors.

ADRA1D ADRA1B ADRA1A

5.16e-076104315525470
Pubmed

α1-Adrenergic Receptors Function Within Hetero-Oligomeric Complexes With Atypical Chemokine Receptor 3 and Chemokine (C-X-C motif) Receptor 4 in Vascular Smooth Muscle Cells.

ADRA1D ADRA1B ADRA1A

5.16e-076104328862946
Pubmed

Expression of adrenergic receptors in mouse preimplantation embryos and ovulated oocytes.

ADRA1D ADRA1B ADRA1A

5.16e-076104317636168
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

FLNA ZNF423 NOTCH2NLA CRELD2 DDB1 SLIT2 FBLN2 FBN1 MPND FHL3 NOTCH2

9.89e-075601041121653829
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FLNA SLC37A3 BCAS3 DLL1 PLXNB2 ZNF865 FANCA PIAS4 FASN TULP4 NEK8 DUSP16 HMGXB3 WDR90 NOTCH2

1.05e-0611051041535748872
Pubmed

Signalling codes for the maintenance and lineage commitment of embryonic gastric epithelial progenitors.

PGC RSPO3 TP63 NOTCH2

1.26e-0627104432878924
Pubmed

Cardiac function in genetically engineered mice with altered adrenergic receptor signaling.

ADRA1D ADRA1B ADRA1A

1.44e-06810439139936
Pubmed

An ultra-high sulfur keratin gene is expressed specifically during hair growth.

KRTAP9-4 KRTAP9-2 KRTAP9-9

1.44e-06810432465353
Pubmed

Molecular evolution of the keratin associated protein gene family in mammals, role in the evolution of mammalian hair.

KRTAP9-4 KRTAP13-2 KRTAP9-2 KRTAP9-9 KRTAP24-1

2.09e-0669104518721477
Pubmed

Adrenergic regulation of AMP-activated protein kinase in brown adipose tissue in vivo.

ADRA1D ADRA1B ADRA1A

2.15e-069104321209093
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

COL4A4 COL12A1 B4GAT1 CRELD2 CPD ADGRE2 PLXNB2 DDB1 DMXL1 FANCA FBN1 FBN2 TBC1D4 NOTCH2 SORL1

2.92e-0612011041535696571
Pubmed

Domperidone treatment for gastroparesis: demographic and pharmacogenetic characterization of clinical efficacy and side-effects.

ADRA1D ADRA1B ADRA1A

3.07e-0610104321063774
Pubmed

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.

COL12A1 FBLN2 FBN1 HMCN2 VCAN COL14A1

5.34e-06146104627068509
Pubmed

Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter.

INSM1 ISM1 DLL1 TP63 NOTCH2

6.23e-0686104535103284
Pubmed

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

COL4A4 COL12A1 FBLN2 FBN1 VCAN COL14A1

6.99e-06153104625037231
Pubmed

Age-dependent blood pressure elevation is due to increased vascular smooth muscle tone mediated by G-protein signalling.

ADRA1D ADRA1B ADRA1A

7.27e-0613104326531127
Pubmed

Insm1 controls development of pituitary endocrine cells and requires a SNAG domain for function and for recruitment of histone-modifying factors.

INSM1 TSHB DLL1 NOTCH2

8.51e-0643104424227653
Pubmed

Homo- and heterotypic fibrillin-1 and -2 interactions constitute the basis for the assembly of microfibrils.

FBN1 FBN2

8.86e-062104212399449
Pubmed

An alpha1A-adrenergic-extracellular signal-regulated kinase survival signaling pathway in cardiac myocytes.

ADRA1B ADRA1A

8.86e-062104217283256
Pubmed

Fibrillin-1 and fibrillin-2 are essential for formation of thick oxytalan fibers in human nonpigmented ciliary epithelial cells in vitro.

FBN1 FBN2

8.86e-062104221851253
Pubmed

Collagen types XII and XIV are present in basement membrane zones during human embryonic development.

COL12A1 COL14A1

8.86e-062104215609093
Pubmed

Confocal laser scanning analysis of the association of fibulin-2 with fibrillin-1 and fibronectin define different stages of skin regeneration.

FBLN2 FBN1

8.86e-06210429886271
Pubmed

New Evidence Supporting the Role of FBN1 in the Development of Adolescent Idiopathic Scoliosis.

FBN1 FBN2

8.86e-062104230044367
Pubmed

Material and mechanical properties of bones deficient for fibrillin-1 or fibrillin-2 microfibrils.

FBN1 FBN2

8.86e-062104221440062
Pubmed

MAGP-2 has multiple binding regions on fibrillins and has covalent periodic association with fibrillin-containing microfibrils.

FBN1 FBN2

8.86e-062104215131124
Pubmed

Inhibition of α9α10 nicotinic acetylcholine receptors prevents chemotherapy-induced neuropathic pain.

CHRNA9 CHRNA10

8.86e-062104228223528
Pubmed

Cross-talk between alpha1D-adrenoceptors and transient receptor potential vanilloid type 1 triggers prostate cancer cell proliferation.

TRPV1 ADRA1D

8.86e-062104225481381
Pubmed

Microfibril structure masks fibrillin-2 in postnatal tissues.

FBN1 FBN2

8.86e-062104220404337
Pubmed

Clinical implications from studies of alpha1 adrenergic receptor knockout mice.

ADRA1D ADRA1B

8.86e-062104217141736
Pubmed

Cell surface expression of alpha1D-adrenergic receptors is controlled by heterodimerization with alpha1B-adrenergic receptors.

ADRA1D ADRA1B

8.86e-062104214736874
Pubmed

Fibrillln mutations in Marfan syndrome and related phenotypes.

FBN1 FBN2

8.86e-06210428791520
Pubmed

Fibrillin genes map to regions of conserved mouse/human synteny on mouse chromosomes 2 and 18.

FBN1 FBN2

8.86e-06210428307578
Pubmed

Nicotinic acetylcholine receptors regulate vestibular afferent gain and activation timing.

CHRNA9 CHRNA10

8.86e-062104227718229
Pubmed

The alpha10 nicotinic acetylcholine receptor subunit is required for normal synaptic function and integrity of the olivocochlear system.

CHRNA9 CHRNA10

8.86e-062104218077337
Pubmed

Early in life stressful events induce chronic visceral pain and changes in bladder function in adult female mice through a mechanism involving TRPV1 and alpha 1A adrenoceptors.

TRPV1 ADRA1A

8.86e-062104238178640
Pubmed

Developmental expression of fibrillin genes suggests heterogeneity of extracellular microfibrils.

FBN1 FBN2

8.86e-06210427744963
Pubmed

Fibrillin microfibrils in bone physiology.

FBN1 FBN2

8.86e-062104226408953
Pubmed

A novel human nicotinic receptor subunit, alpha10, that confers functionality to the alpha9-subunit.

CHRNA9 CHRNA10

8.86e-062104211752216
Pubmed

Arg-Gly-Asp-containing domains of fibrillins-1 and -2 distinctly regulate lung fibroblast migration.

FBN1 FBN2

8.86e-062104218006876
Pubmed

Versican interacts with fibrillin-1 and links extracellular microfibrils to other connective tissue networks.

FBN1 VCAN

8.86e-062104211726670
Pubmed

Rare variants in FBN1 and FBN2 are associated with severe adolescent idiopathic scoliosis.

FBN1 FBN2

8.86e-062104224833718
Pubmed

Fibrillin-1 and fibulin-2 interact and are colocalized in some tissues.

FBLN2 FBN1

8.86e-06210428702639
Pubmed

Deletion of nicotinic acetylcholine receptor alpha9 in mice resulted in altered bone structure.

CHRNA9 CHRNA10

8.86e-062104230414510
Pubmed

Homotypic versican G1 domain interactions enhance hyaluronan incorporation into fibrillin microfibrils.

FBN1 VCAN

8.86e-062104223963449
Pubmed

The COL12A1 and COL14A1 genes and Achilles tendon injuries.

COL12A1 COL14A1

8.86e-062104217960519
Pubmed

A point mutation in the hair cell nicotinic cholinergic receptor prolongs cochlear inhibition and enhances noise protection.

CHRNA9 CHRNA10

8.86e-062104219166271
Pubmed

Nonselective assembly of fibrillin 1 and fibrillin 2 in the rodent ocular zonule and in cultured cells: implications for Marfan syndrome.

FBN1 FBN2

8.86e-062104224265020
Pubmed

In vivo studies of mutant fibrillin-1 microfibrils.

FBN1 FBN2

8.86e-062104220529844
Pubmed

B-cell deficiency does not abrogate development of cutaneous hyperplasia in mice inheriting the defective fibrillin-1 gene.

RAG2 FBN1

8.86e-06210429451590
Pubmed

Fibrillin-1 mutations causing Weill-Marchesani syndrome and acromicric and geleophysic dysplasias disrupt heparan sulfate interactions.

FBN1 FBN2

8.86e-062104223133647
Pubmed

alpha(1)-adrenoceptor subtypes differentially couple to growth promotion and inhibition in Chinese hamster ovary cells.

ADRA1D ADRA1A

8.86e-062104210860850
Pubmed

Nuclear alpha1-adrenergic receptors signal activated ERK localization to caveolae in adult cardiac myocytes.

ADRA1B ADRA1A

8.86e-062104218802028
Pubmed

Phosphocholine - an agonist of metabotropic but not of ionotropic functions of α9-containing nicotinic acetylcholine receptors.

CHRNA9 CHRNA10

8.86e-062104227349288
Pubmed

Linkage of Marfan syndrome and a phenotypically related disorder to two different fibrillin genes.

FBN1 FBN2

8.86e-06210421852206
Pubmed

Molecular basis for the differential sensitivity of rat and human α9α10 nAChRs to α-conotoxin RgIA.

CHRNA9 CHRNA10

8.86e-062104222774872
Pubmed

Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins.

TNPO1 TNPO2

8.86e-06210429298975
Pubmed

The mouse tight skin (Tsk) phenotype is not dependent on the presence of mature T and B lymphocytes.

RAG2 FBN1

8.86e-06210429799844
Pubmed

Transcriptional responses to growth factor and G protein-coupled receptors in PC12 cells: comparison of alpha(1)-adrenergic receptor subtypes.

ADRA1D ADRA1B

8.86e-062104210820200
Pubmed

Alpha1-adrenergic receptors prevent a maladaptive cardiac response to pressure overload.

ADRA1B ADRA1A

8.86e-062104216585965
Pubmed

Fibrillins can co-assemble in fibrils, but fibrillin fibril composition displays cell-specific differences.

FBN1 FBN2

8.86e-062104212429739
Pubmed

Characterization of HA-tagged α9 and α10 nAChRs in the mouse cochlea.

CHRNA9 CHRNA10

8.86e-062104233311584
Pubmed

Notch ligation by Delta1 inhibits peripheral immune responses to transplantation antigens by a CD8+ cell-dependent mechanism.

DLL1 NOTCH2

8.86e-062104214660750
Pubmed

Oligomerization of the alpha 1a- and alpha 1b-adrenergic receptor subtypes. Potential implications in receptor internalization.

ADRA1B ADRA1A

8.86e-062104212888550
Pubmed

Abnormal corneal endothelial maturation in collagen XII and XIV null mice.

COL12A1 COL14A1

8.86e-062104223599329
Pubmed

Fibrillin-1 and fibrillin-2 in human embryonic and early fetal development.

FBN1 FBN2

8.86e-062104212524050
Pubmed

Transportin-1 and Transportin-2: protein nuclear import and beyond.

TNPO1 TNPO2

8.86e-062104224780099
Pubmed

alpha(1A)- and alpha(1B)-adrenergic receptors differentially modulate antidepressant-like behavior in the mouse.

ADRA1B ADRA1A

8.86e-062104219540213
Pubmed

The alpha(1A/C)- and alpha(1B)-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouse.

ADRA1B ADRA1A

8.86e-062104212782680
InteractionZFP41 interactions

CRELD2 FASN FBN1 FBN2 NOTCH2 SORL1

4.02e-07571016int:ZFP41
InteractionFBN1 interactions

PLXNB2 FBLN2 FBN1 FBN2 VCAN

5.60e-06511015int:FBN1
InteractionNTN5 interactions

FBN1 FBN2 NOTCH2 SORL1

5.85e-06241014int:NTN5
InteractionSLURP1 interactions

DMXL2 DYNC2I2 CRELD2 PLXNB2 VCAN NOTCH2 SORL1

8.07e-061441017int:SLURP1
InteractionZNF408 interactions

NOTCH2NLA FASN FBLN2 FBN1 FBN2 NOTCH2 SORL1

8.44e-061451017int:ZNF408
InteractionHOXA1 interactions

ZBTB16 KRTAP9-4 KRTAP13-2 NOTCH2NLA CRELD2 SLIT2 FBLN2 FBN1 KRTAP9-2 FHL3

1.21e-0535610110int:HOXA1
InteractionFBLN2 interactions

COL4A4 ZNF865 FBLN2 FBN1 VCAN

2.01e-05661015int:FBLN2
InteractionFBXO2 interactions

COL12A1 CPD PLXNB2 SLIT2 FBN1 FBN2 COL14A1 SEMA6A NOTCH2 SORL1

4.11e-0541110110int:FBXO2
InteractionDCN interactions

COL4A4 FLNA FBN1 COL14A1

6.31e-05431014int:DCN
InteractionGIP interactions

COL12A1 NOTCH2NLA CRELD2 COL14A1

6.92e-05441014int:GIP
InteractionST14 interactions

CRELD2 SLIT2 FBN1 FBN2 VCAN SEMA6A NOTCH2

8.29e-052071017int:ST14
InteractionLTBP1 interactions

FASN FBLN2 FBN1 FBN2 NOTCH2

9.96e-05921015int:LTBP1
InteractionADAMTSL4 interactions

FLNA KRTAP9-4 NOTCH2NLA NEK8 KRTAP9-2 ZFHX2 FHL3

1.11e-042171017int:ADAMTSL4
InteractionCCN6 interactions

CRELD2 NOTCH2 SORL1

1.12e-04191013int:CCN6
GeneFamilyAdrenoceptors

ADRA1D ADRA1B ADRA1A

4.59e-069703169
GeneFamilyKeratin associated proteins

KRTAP9-4 KRTAP13-2 KRTAP9-2 KRTAP9-9 KRTAP24-1

6.44e-05109705619
GeneFamilyWD repeat domain containing

DMXL2 DYNC2I2 BCAS3 DMXL1 TULP4 WDR90 BRWD1

6.82e-05262707362
GeneFamilyCD molecules|Adhesion G protein-coupled receptors, subfamily E

ADGRE2 ADGRE3

1.47e-045702915
GeneFamilyFibulins

FBLN2 HMCN2

4.08e-048702556
GeneFamilyCollagens

COL4A4 COL12A1 COL14A1

7.49e-0446703490
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZEB1 ZFHX2

1.50e-0315702529
GeneFamilyCholinergic receptors nicotinic subunits

CHRNA9 CHRNA10

1.71e-0316702173
GeneFamilyArmadillo repeat containing|Importins

TNPO1 TNPO2

2.17e-0318702596
CoexpressionNABA_CORE_MATRISOME

COL4A4 COL12A1 CRELD2 SVEP1 RSPO3 SLIT2 FBLN2 FBN1 FBN2 IGFALS HMCN2 VCAN COL14A1 FBN3

3.67e-1227510214M5884
CoexpressionNABA_CORE_MATRISOME

COL4A4 COL12A1 CRELD2 SVEP1 RSPO3 SLIT2 FBLN2 FBN1 FBN2 IGFALS HMCN2 VCAN COL14A1

4.56e-1127010213MM17057
CoexpressionNABA_ECM_GLYCOPROTEINS

CRELD2 SVEP1 RSPO3 SLIT2 FBLN2 FBN1 FBN2 IGFALS HMCN2 FBN3

5.09e-0919610210M3008
CoexpressionNABA_MATRISOME

COL4A4 COL12A1 ISM1 CRELD2 PLXNB2 SVEP1 RSPO3 SLIT2 FBLN2 FBN1 FBN2 IGFALS HMCN2 EGF ADAM5 VCAN COL14A1 SEMA6A MUC4

1.08e-08100810219MM17056
CoexpressionNABA_MATRISOME

COL4A4 COL12A1 ISM1 CRELD2 PLXNB2 SVEP1 RSPO3 SLIT2 FBLN2 FBN1 FBN2 IGFALS HMCN2 EGF VCAN COL14A1 SEMA6A MUC4 FBN3

1.43e-08102610219M5889
CoexpressionNABA_ECM_GLYCOPROTEINS

CRELD2 SVEP1 RSPO3 SLIT2 FBLN2 FBN1 FBN2 IGFALS HMCN2

6.13e-081911029MM17059
CoexpressionHALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION

FLNA COL12A1 SLIT2 FBLN2 FBN1 FBN2 VCAN NOTCH2

1.19e-062001028M5930
CoexpressionDESCARTES_FETAL_THYMUS_STROMAL_CELLS

COL12A1 FBLN2 FBN1 FBN2 VCAN COL14A1

1.63e-051371026M40313
CoexpressionVECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_UP

COL12A1 ZNF423 ISM1 SLIT2 FBN1 VCAN

7.08e-051781026M17079
CoexpressionBOQUEST_STEM_CELL_UP

NOTCH2NLA SVEP1 SLIT2 FBN1 VCAN COL14A1 NOTCH2

7.40e-052611027M1834
CoexpressionDEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN

FLNA B4GAT1 PLXNB2 FANCA FBN2 VCAN SORL1

1.05e-042761027M3063
CoexpressionGSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_14H_DN

ATP10A CALHM4 ADRA1B HMCN2 DUSP16 SEMA6A

1.07e-041921026M4277
CoexpressionLIM_MAMMARY_STEM_CELL_UP

COL12A1 ZNF423 ISM1 DLL1 SVEP1 SLIT2 TP63 VCAN COL14A1

1.07e-044791029M2573
CoexpressionLIM_MAMMARY_STEM_CELL_UP

COL12A1 ZNF423 ISM1 DLL1 SVEP1 SLIT2 TP63 VCAN COL14A1

1.14e-044831029MM1082
CoexpressionGSE34156_NOD2_LIGAND_VS_TLR1_TLR2_LIGAND_6H_TREATED_MONOCYTE_DN

ZNF787 DMXL2 ADGRE2 PLXNB2 ADGRE3 VCAN

1.24e-041971026M8686
CoexpressionGSE23984_CTRL_VS_HYPOCALEMIC_VITAMIND_ANALOG_TCELL_UP

DMXL2 CPD METAP1 FASN SPIDR ADGRL2

1.34e-042001026M8051
CoexpressionGSE29618_MONOCYTE_VS_MDC_UP

DMXL2 CPD FBN2 VCAN NOTCH2 SORL1

1.34e-042001026M4948
CoexpressionTURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_DUCTAL_NORMAL_UP

ZEB1 COL12A1 FBN1 VCAN

1.54e-04691024M10165
CoexpressionDI_MARTINO_MATRISOME_HIGHLY_PROLIFERATIVE_HNSCC

COL12A1 FBLN2 FBN2

1.56e-04271023M47994
CoexpressionAtlasfacebase_RNAseq_e10.5_MandArch_2500_K4

ZBTB16 RNASE13 STPG1 ELAPOR1 LYPD3 SNX31

1.59e-0681946facebase_RNAseq_e10.5_MandArch_2500_K4
CoexpressionAtlasdev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_1000

COL12A1 SVEP1 RSPO3 SLIT2 FBN1 FBN2 VCAN COL14A1

2.09e-05261948gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k4_1000
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_1000

FLNA PLXNB2 SVEP1 SLIT2 FBLN2 FBN1 FBN2 VCAN COL14A1 SEMA6A SPIDR ADGRL2 NOTCH2

7.05e-058279413gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_1000
CoexpressionAtlasStromal Cells, Ep.MEChi.Th, CD45-EpCAm+Ly51-MHCIIhi, Thymus, avg-1

COL12A1 INSM1 CPD PGC DUSP16 ELAPOR1 COL14A1 ADGRL2 HDC

8.71e-05411949GSM854302_500
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_500

FLNA SVEP1 SLIT2 FBN1 FBN2 VCAN COL14A1 SPIDR ADGRL2

9.90e-05418949gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_500
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D231|Adult / Lineage, Cell type, age group and donor

ZEB1 ISM1 SVEP1 RSPO3 SLIT2 FBLN2 FBN1 HMCN2 COL14A1

4.97e-101851039fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCellLV-02._Fibroblast_II|World / Chamber and Cluster_Paper

COL4A4 ZEB1 COL12A1 ZBTB16 SVEP1 SLIT2 FBLN2 FBN1 VCAN

6.60e-101911039d36565257ccba8c1bbed2c1c01be66a9cbb5f834
ToppCellLA|World / Chamber and Cluster_Paper

ZEB1 COL12A1 SVEP1 SLIT2 FASN FBLN2 FBN1 HMCN2 VCAN

7.23e-101931039d4bf89437216baf489ea0239136dcedf3b6714af
ToppCellLV-02._Fibroblast_II|LV / Chamber and Cluster_Paper

COL4A4 ZEB1 COL12A1 ZBTB16 SVEP1 SLIT2 FBLN2 FBN1 VCAN

7.57e-101941039014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

COL4A4 COL12A1 SVEP1 SLIT2 FBLN2 FBN1 HMCN2 VCAN NOTCH2

7.57e-101941039d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA ZEB1 COL12A1 ISM1 ATP10A SVEP1 RSPO3 FBN1 VCAN

7.92e-10195103949c99553629cdd83ee56a2e508d5bc8d34b8507b
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL12A1 ISM1 SVEP1 RSPO3 SLIT2 FBLN2 FBN1 VCAN COL14A1

7.92e-101951039f54bc4454270ff06e85596f98199372b50d0179f
ToppCellLA-02._Fibroblast_II|World / Chamber and Cluster_Paper

COL4A4 ZEB1 COL12A1 SVEP1 SLIT2 FBLN2 FBN1 HMCN2 VCAN

7.92e-101951039a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA ZEB1 COL12A1 ISM1 ATP10A SVEP1 RSPO3 FBN1 VCAN

7.92e-101951039dd281a249854800f737dc22e0f375f66dfb5cf5f
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZEB1 ZNF423 SVEP1 RSPO3 SLIT2 FBLN2 FBN1 VCAN COL14A1

9.90e-102001039ad3fdcef895400f929f2ae12ff9bd85fd46adb3a
ToppCellTracheal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZEB1 COL12A1 ISM1 SVEP1 SLIT2 FBLN2 FBN1 VCAN COL14A1

9.90e-102001039b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZEB1 COL12A1 ISM1 SVEP1 SLIT2 FBLN2 FBN1 VCAN COL14A1

9.90e-1020010390c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_3|E16.5-samps / Age Group, Lineage, Cell class and subclass

COL12A1 SVEP1 SLIT2 VCAN COL14A1 WDR90 CHRNA10 NOTCH2

2.18e-091491038651494e84be03dc7b061ebdfa91756a1c507b9b4
ToppCellCOVID-19-Heart-Fib_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

ZEB1 COL12A1 SVEP1 SLIT2 FBLN2 FBN1 HMCN2 VCAN

1.20e-0818510388f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

COL4A4 COL12A1 SVEP1 SLIT2 FBLN2 FBN1 HMCN2 VCAN

1.30e-0818710384ea486991f66c29728d127171a07b81404ec0b78
ToppCellCOVID-19-Heart-Fib_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

COL4A4 ZEB1 COL12A1 SVEP1 SLIT2 FBLN2 FBN1 HMCN2

1.36e-081881038fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D175|Adult / Lineage, Cell type, age group and donor

ZEB1 ZNF423 ISM1 SVEP1 SLIT2 FBLN2 FBN1 COL14A1

1.47e-0819010387dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SVEP1 RSPO3 SLIT2 FBLN2 FBN1 FBN2 VCAN COL14A1

1.60e-0819210388937a59f6bbe07f671bdabbd3707dc9c17a14cd9
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SVEP1 RSPO3 SLIT2 FBLN2 FBN1 FBN2 VCAN COL14A1

1.60e-081921038e4a7f2673f801b008ca67291db2fb2b9fd2955b8
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SVEP1 RSPO3 SLIT2 FBLN2 FBN1 FBN2 VCAN COL14A1

1.60e-081921038ac1477433704573f95111eee6263b93668d2845e
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell|Adult / Lineage, Cell type, age group and donor

ZEB1 ZNF423 ISM1 SVEP1 SLIT2 FBLN2 FBN1 COL14A1

1.60e-081921038d21f0f577156f17c899b08871046a26b88aea011
ToppCellMesenchymal-matrix_fibroblast_2_cell|World / Lineage, Cell type, age group and donor

COL12A1 ZNF423 SVEP1 RSPO3 SLIT2 FBLN2 FBN1 COL14A1

1.60e-081921038a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCellLV-01._Fibroblast_I|LV / Chamber and Cluster_Paper

COL4A4 COL12A1 ZBTB16 SVEP1 SLIT2 FBLN2 FBN1 VCAN

1.66e-081931038dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCellLA-02._Fibroblast_II|LA / Chamber and Cluster_Paper

COL4A4 ZEB1 ZBTB16 SVEP1 SLIT2 FBLN2 FBN1 VCAN

1.73e-081941038234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCellCOVID-19-Heart-Fib_1|Heart / Disease (COVID-19 only), tissue and cell type

COL4A4 COL12A1 SVEP1 SLIT2 FBLN2 FBN1 VCAN NOTCH2

1.80e-081951038f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCell11.5-Airway-Mesenchymal-Mesenchyme_SERPINF1-high|Airway / Age, Tissue, Lineage and Cell class

ZEB1 COL12A1 ISM1 RSPO3 FBLN2 FBN1 FBN2 COL14A1

1.95e-0819710389a053a32ff9c3a85ef9a3382453acd619cc48546
ToppCellBronchus_Control_(B.)-Stromal-TX-Fibroblasts-2,_SCARA5|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

COL12A1 ZBTB16 ZNF423 ISM1 SVEP1 FBLN2 FBN1 COL14A1

2.20e-0820010382022df85df94ab8cbb4e80e3fe9894c01051c5e0
ToppCell5'-Adult-SmallIntestine-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA COL12A1 SVEP1 RSPO3 SLIT2 FBN1 VCAN COL14A1

2.20e-082001038a637281d91e95734ee4f8510b3780e0272b16fda
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL12A1 SVEP1 RSPO3 SLIT2 FBLN2 FBN1 VCAN COL14A1

2.20e-0820010386f7f015b5fa1f52374f2c7d9ba339012395eda5f
ToppCellBronchus_Control_(B.)-Stromal-TX|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

COL12A1 ZBTB16 ZNF423 ISM1 SVEP1 FBLN2 FBN1 COL14A1

2.20e-08200103869b41f5fb370aa8840a9ad7919d03ef1e57d1b5b
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL12A1 SVEP1 RSPO3 SLIT2 FBLN2 FBN1 VCAN COL14A1

2.20e-0820010383a164e3971bcd62b148b813171c103adb81f972e
ToppCellBronchial-10x5prime-Stromal-Fibroblastic-Fibro_adventitial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL12A1 ZNF423 SVEP1 RSPO3 SLIT2 FBLN2 FBN1 COL14A1

2.20e-082001038b04831708fa20471a127b87e8db3728b6e729ce8
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZEB1 SVEP1 RSPO3 SLIT2 FBLN2 FBN1 VCAN COL14A1

2.20e-08200103874e74123ea7bf38d337a3a0248a6a51437c6ab42
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF423 ISM1 SLIT2 FBLN2 FBN1 VCAN COL14A1 ADGRL2

2.20e-082001038fb53be20392a8309a7393774c774a1b1aec6e676
ToppCell5'-Adult-LargeIntestine-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL12A1 ZBTB16 SVEP1 RSPO3 FBLN2 FBN1 VCAN COL14A1

2.20e-0820010385a87bb8eb1c6bd2fbc357e1528e15ba1c0051438
ToppCellRA-01._Fibroblast_I|RA / Chamber and Cluster_Paper

COL4A4 ZBTB16 SLIT2 FBLN2 FBN1 VCAN ZNF804B

1.36e-0716910376373562ab3b1765060212a6a53d6543e7e942e80
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 DPRX SVEP1 SLIT2 FBN1 VCAN COL14A1

1.48e-0717110375d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL12A1 ISM1 SVEP1 SLIT2 FBLN2 FBN1 COL14A1

1.54e-071721037e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 SVEP1 SLIT2 ADRA1D ADRA1A FBN1 COL14A1

1.73e-071751037795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCell356C-Fibroblasts-Fibroblast-E-|356C / Donor, Lineage, Cell class and subclass (all cells)

TRPV1 ZNF423 SVEP1 RSPO3 FBLN2 FBN1 COL14A1

1.94e-071781037a493a277d175e5e153410a745b26ebe2e0839ea0
ToppCell356C-Fibroblasts-Fibroblast-E|356C / Donor, Lineage, Cell class and subclass (all cells)

TRPV1 ZNF423 SVEP1 RSPO3 FBLN2 FBN1 COL14A1

1.94e-071781037371218babddfd3d8a7bb82a46ce65327ee3fcf12
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL4A4 ADRA1B FBLN2 FBN1 FBXL18 VCAN COL14A1

2.71e-071871037fa8f221b4c2df61eadaa9c77e4cf45848b00330b
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SVEP1 RSPO3 FBLN2 FBN1 FBN2 VCAN COL14A1

2.71e-0718710374e553721fa5598cb211f44e3226280b7e6885484
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SVEP1 RSPO3 FBLN2 FBN1 FBN2 VCAN COL14A1

2.71e-071871037d36e7fc6125e7a4310499365022d38f34b757a73
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SVEP1 RSPO3 FBLN2 FBN1 FBN2 VCAN COL14A1

2.71e-071871037827eae63fabf6892a82ce7779b5f395958d3d628
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZEB1 COL12A1 SVEP1 RSPO3 FBLN2 FBN1 HMCN2

2.81e-071881037ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCellLV-01._Fibroblast_I|World / Chamber and Cluster_Paper

COL4A4 ZEB1 COL12A1 ZBTB16 SVEP1 SLIT2 FBN1

3.02e-07190103712992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZEB1 COL12A1 ATP10A SVEP1 ADRA1A FBN1 VCAN

3.02e-07190103770c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A4 COL12A1 SVEP1 ADRA1B FBN1 VCAN COL14A1

3.13e-07191103739092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A4 COL12A1 SVEP1 ADRA1B FBN1 VCAN COL14A1

3.13e-071911037ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCellRV-01._Fibroblast_I|RV / Chamber and Cluster_Paper

COL4A4 COL12A1 SVEP1 SLIT2 FBLN2 FBN1 VCAN

3.24e-071921037356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

COL4A4 ZEB1 COL12A1 SVEP1 SLIT2 FBN1 VCAN

3.24e-07192103760b1312e84f6d6448365a952469c506c00b5fe93
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ZNF423 SVEP1 RSPO3 SLIT2 FBLN2 FBN1 COL14A1

3.24e-071921037e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 SVEP1 FBN1 HMCN2 VCAN COL14A1 FHL3

3.35e-071931037dc8e62df6121ee99b156aca6b1b3ae555739b6f2
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ZNF423 SVEP1 RSPO3 SLIT2 FBLN2 FBN1 COL14A1

3.35e-0719310379ab47b360bee1d4f1092c2269e58acebe9584021
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 SVEP1 FBN1 HMCN2 VCAN COL14A1 FHL3

3.35e-071931037e2ee077fd381bd906e6b4329f22e7d106e422a7f
ToppCellRV-02._Fibroblast_II|RV / Chamber and Cluster_Paper

COL4A4 ZEB1 SVEP1 SLIT2 FBLN2 FBN1 VCAN

3.47e-07194103711c79a8c56ece42713b04b321982e41e239f07a5
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A4 COL12A1 ATP10A SVEP1 FBN1 VCAN COL14A1

3.47e-071941037240d122dcb9dd1ab2867503ad85869853adcacae
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL12A1 SVEP1 RSPO3 FBLN2 FBN1 HMCN2 COL14A1

3.47e-071941037439d3f17c1f4736122b330e98add9292c7036a8e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A4 COL12A1 ATP10A SVEP1 FBN1 VCAN COL14A1

3.47e-071941037ae7df037592f1c20c9d32be15fe6fc3c562ebeb1
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ZBTB16 ZNF423 SVEP1 RSPO3 SLIT2 FBN1 HMCN2

3.60e-071951037ff0aa455e9844a6d7ae57ff59fb6cea825cf1fc2
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ISM1 SVEP1 SLIT2 ADRA1B FBN1 VCAN COL14A1

3.60e-071951037cbe518b465b4ef32797ae6b608219207c08493df
ToppCellPND03-Mesenchymal-Mesenchymal_structural|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ISM1 SVEP1 SLIT2 ADRA1B FBN1 VCAN COL14A1

3.60e-071951037136b06b0931a69b1241101f68c01c44c70365fd9
ToppCellRV-02._Fibroblast_II|World / Chamber and Cluster_Paper

COL4A4 ZEB1 ZBTB16 SVEP1 SLIT2 FBN1 VCAN

3.60e-071951037ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCellRA-02._Fibroblast_II|RA / Chamber and Cluster_Paper

COL4A4 ZBTB16 SVEP1 SLIT2 FBLN2 FBN1 VCAN

3.60e-0719510376a02ebbeb3199447ddce64d92d8809436e040eba
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA ZBTB16 ATP10A RSPO3 ADRA1A HMCN2 COL14A1

3.72e-0719610371522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA ZBTB16 ATP10A RSPO3 ADRA1A HMCN2 COL14A1

3.72e-0719610371c8294014713684b50885e638668f2ce75f357f0
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PGC SVEP1 SLIT2 FASN FBLN2 FBN1 COL14A1

3.72e-071961037988a3e0688e0a7ba69774497d3b130631bb26c50
ToppCell10x3'2.3-week_17-19-Mesenchymal_adipo|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

COL12A1 SVEP1 RSPO3 SLIT2 FBN1 VCAN COL14A1

3.85e-0719710375afddde4e2b5cd55abe11e9b9efae02dbdc3da3a
ToppCell10x3'2.3-week_17-19-Mesenchymal_adipo-stroma-adipo-CAR|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

COL12A1 SVEP1 RSPO3 SLIT2 FBN1 VCAN COL14A1

3.85e-0719710371baffd087ca194a7355fefbb3bf67befb14fe2de
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZEB1 ISM1 SVEP1 SLIT2 FBLN2 FBN1 VCAN

3.85e-07197103744673c38384453207871d3fd8e8ba9093cc06bc5
ToppCell10x3'2.3-week_17-19-Mesenchymal_adipo-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

COL12A1 SVEP1 RSPO3 SLIT2 FBN1 VCAN COL14A1

3.85e-071971037b9745e382baa2725dfcae060701fb53f6c8a31fa
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL12A1 ISM1 RSPO3 SLIT2 FBLN2 FBN1 COL14A1

3.85e-071971037c747c496ac090309b7f8a3e9d840928f12c83f2f
ToppCell10x3'2.3-week_14-16-Mesenchymal_adipo-stroma-adipo-CAR|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL12A1 SVEP1 RSPO3 SLIT2 FBN1 COL14A1 ADGRL2

3.99e-071981037a8c21f4db6730d0aa05b61fbe72bf9f7571a9015
ToppCell10x3'2.3-week_14-16-Mesenchymal_adipo-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL12A1 SVEP1 RSPO3 SLIT2 FBN1 COL14A1 ADGRL2

3.99e-0719810378b68fc887e5ad0a59ea4d93dfd1edda67030f142
ToppCelltumor_Lung-Fibroblasts-COL14A1+_matrix_FBs|tumor_Lung / Location, Cell class and cell subclass

ISM1 SVEP1 RSPO3 SLIT2 FBLN2 FBN1 COL14A1

3.99e-07198103774f2c7ef702b25a5b99e56121229e678ed992524
ToppCellE18.5-Mesenchymal|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNA ISM1 SVEP1 SLIT2 FBN1 VCAN COL14A1

3.99e-071981037a16aa41eab2e297e56de43c22c355df0f79315da
ToppCellbackground-Hepatic_Stellate_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

COL4A4 COL12A1 SVEP1 RSPO3 SLIT2 FBN1 COL14A1

3.99e-071981037bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCell10x3'2.3-week_14-16-Mesenchymal_adipo|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL12A1 SVEP1 RSPO3 SLIT2 FBN1 COL14A1 ADGRL2

3.99e-0719810374739b2e4ab141c66772e61686b45614a1839483e
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ISM1 NOTCH2NLA SVEP1 FBLN2 FBN1 EDAR COL14A1

4.12e-071991037dfc5c7a4a093baa7158dd8d4d29a870d9c469a3f
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL12A1 SVEP1 RSPO3 FBN1 FBN2 VCAN COL14A1

4.12e-07199103784545ced0c792bc77980a50d65e484eab648d47e
ToppCellmLN-(4)_Monocyte|mLN / shred on region, Cell_type, and subtype

TMEM150B DMXL2 ADGRE2 PLXNB2 SLIT2 FBN2 VCAN

4.12e-0719910376795ff31f92580195c9db776951f99d647484d24
ToppCellBronchial-10x5prime-Stromal-Fibroblastic-Fibro_immune_recruiting|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A4 SVEP1 RSPO3 SLIT2 ADRA1A ZNF804B COL14A1

4.12e-0719910370cdbedf09ec72734b86ddab3fec562e066afed92
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL12A1 SVEP1 RSPO3 SLIT2 FBN1 VCAN COL14A1

4.12e-071991037103f657132e830a0e5efeb745afb4b77c208a1fa
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA SVEP1 RSPO3 FBN1 FBN2 VCAN COL14A1

4.12e-07199103736c1deac7ef0f9ebde6b2f7a63f7daa03d8c139a
ToppCell10x5'v1-week_14-16-Mesenchymal_adipo-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL12A1 SVEP1 RSPO3 SLIT2 FBN1 VCAN COL14A1

4.12e-0719910379b2262edbdec89166d895ab97527e0ee5f9b6010
ToppCellmLN-Monocyte|mLN / Region, Cell class and subclass

TMEM150B DMXL2 ADGRE2 PLXNB2 SLIT2 FBN2 VCAN

4.12e-071991037241f790cd5d8a9b2451333deecc826a673bae70a
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL12A1 SVEP1 RSPO3 FBN1 FBN2 VCAN COL14A1

4.12e-0719910378d71e1fc92ee24deedf23fbb1a85a7fba0d8d436
ToppCell10x5'v1-week_14-16-Mesenchymal_adipo|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL12A1 SVEP1 RSPO3 SLIT2 FBN1 VCAN COL14A1

4.12e-071991037251b3643dcd8f4645b17101bd716e66f12a20e88
ToppCellmLN-Monocyte-Monocyte|mLN / Region, Cell class and subclass

TMEM150B DMXL2 ADGRE2 PLXNB2 SLIT2 FBN2 VCAN

4.12e-071991037dcee372774c169a3048bdaed3734b3215bf8ffad
ToppCellmLN-(4)_Monocyte-(40)_Monocyte|mLN / shred on region, Cell_type, and subtype

TMEM150B DMXL2 ADGRE2 PLXNB2 SLIT2 FBN2 VCAN

4.12e-071991037bcbb1eee8d79bf670dbe113094c3a292b135ce2f
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-immature_mesenchymal_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL12A1 SVEP1 RSPO3 FBN1 FBN2 VCAN COL14A1

4.12e-07199103749690494270981eec5b5261c59e0545dff90cc21
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL12A1 ISM1 SVEP1 SLIT2 FBLN2 FBN1 COL14A1

4.12e-071991037fb580e9321ddf97c73b2e356cd82523db74a38a2
ToppCell10x5'v1-week_14-16-Mesenchymal_adipo-stroma-adipo-CAR|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL12A1 SVEP1 RSPO3 SLIT2 FBN1 VCAN COL14A1

4.12e-071991037117f4f43b6c06dda553799b1063e827bce697370
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ISM1 NOTCH2NLA SVEP1 FBLN2 FBN1 EDAR COL14A1

4.12e-071991037c1760581c34b81d1d92c67500a1c8944e9cc6dad
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL12A1 SVEP1 RSPO3 FBLN2 FBN1 VCAN COL14A1

4.26e-072001037933b5b400e48a511ba0a056be1d33d3610b5f10d
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-2,_SCARA5-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SVEP1 RSPO3 SLIT2 FBLN2 FBN1 VCAN COL14A1

4.26e-0720010370b2614b8513693dd508c9003699049efd9abac52
ToppCell5'-Adult-Distal_Rectal-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL12A1 SVEP1 RSPO3 FBLN2 FBN1 VCAN COL14A1

4.26e-072001037db6281b5d4032116310db379d9175d790994c99c
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL12A1 SVEP1 RSPO3 FBLN2 FBN1 VCAN COL14A1

4.26e-072001037cfea2f9d85646c9b722150551ff2e8fc4f6cc98a
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZEB1 COL12A1 ISM1 SVEP1 FBN1 VCAN COL14A1

4.26e-072001037a4ec0e80f5422b91b85264a9bb74568dd577e285
Drug1-(2-(3-methoxyphenyl)ethyl)phenoxy-3-(dimethylamino)-2-propanol

ADRA1D ADRA1B ADRA1A

8.73e-0831023ctd:C099060
DrugAlfuzosin

ADRA1D ADRA1B ADRA1A

8.73e-0831023DB00346
DrugPhenylephrine

ADRA1D ADRA1B ADRA1A

8.73e-0831023DB00388
DrugDapiprazole

ADRA1D ADRA1B ADRA1A

8.73e-0831023DB00298
Drug2-(beta-(3-iodo-4-hydroxyphenyl)ethylaminomethyl)tetralone

ADRA1D ADRA1B ADRA1A

8.73e-0831023ctd:C048008
DrugTamsulosin

ADRA1D ADRA1B ADRA1A

8.73e-0831023DB00706
Drugabanoquil

ADRA1D ADRA1B ADRA1A

8.73e-0831023ctd:C058534
Drugifoxetine

ADRA1D ADRA1B ADRA1A

8.73e-0831023CID000071971
Drugchlorethylclonidine

ADRA1D ADRA1B ADRA1A

8.73e-0831023ctd:C051731
DrugWy 25309

ADRA1D ADRA1B ADRA1A

8.73e-0831023CID000133818
DrugXB513

ADRA1D ADRA1B ADRA1A

8.73e-0831023CID000183813
Drugtamsulosin

ADRA1D ADRA1B ADRA1A

3.48e-0741023ctd:C088482
Drugsertindole

ADRA1D ADRA1B ADRA1A

3.48e-0741023ctd:C066304
DrugBE 2254

ADRA1D ADRA1B ADRA1A

3.48e-0741023ctd:C010652
Drug5-methylurapidil

ADRA1D ADRA1B ADRA1A

3.48e-0741023ctd:C057446
DrugLeniquinsin

ADRA1D ADRA1B ADRA1A

8.67e-0751023CID000025195
DrugAC1L9NP0

ADRA1D ADRA1B ADRA1A

8.67e-0751023CID000449842
DrugS-10089

ADRA1D ADRA1B ADRA1A

8.67e-0751023CID000146399
DrugCS-263

ADRA1D ADRA1B ADRA1A

8.67e-0751023CID000137303
Drug5-methylgramine

ADRA1D ADRA1B ADRA1A

8.67e-0751023CID000034855
Drugmetazosin

ADRA1D ADRA1B ADRA1A

8.67e-0751023CID000093514
DrugAC1O6ABX

ADRA1D ADRA1B ADRA1A

8.67e-0751023CID006449894
DrugKABI 2023

ADRA1D ADRA1B ADRA1A

8.67e-0751023CID000192124
DrugA-53693

ADRA1D ADRA1B ADRA1A

8.67e-0751023CID003082713
Drugmethylatropine

CHRNA9 TSHB ADRA1B ADRA1A CHRNA10

9.50e-07401025CID000005860
Drugtripelennamine

ZEB1 ADRA1D ADRA1B ADRA1A IGFALS

1.22e-06421025CID000005587
DrugDoxazosin

ADRA1D ADRA1B ADRA1A

1.73e-0661023DB00590
DrugPrazosin

ADRA1D ADRA1B ADRA1A

1.73e-0661023DB00457
DrugBr-pindolol

ADRA1D ADRA1B ADRA1A

1.73e-0661023CID000125847
DrugTerazosin

ADRA1D ADRA1B ADRA1A

1.73e-0661023DB01162
DrugTerazosin

ADRA1D ADRA1B ADRA1A

1.73e-0661023ctd:C041226
DrugBMY 7378

ADRA1D ADRA1B ADRA1A

1.73e-0661023ctd:C053428
DrugXylometazoline

ADRA1D ADRA1B ADRA1A

1.73e-0661023DB06694
Drugalfuzosin

ADRA1D ADRA1B ADRA1A

1.73e-0661023ctd:C047638
Drugdibozane

ADRA1D ADRA1B ADRA1A

1.73e-0661023CID000094342
DrugNaphazoline

ADRA1D ADRA1B ADRA1A

3.02e-0671023ctd:D009278
Drugxylometazoline

ADRA1D ADRA1B ADRA1A

3.02e-0671023ctd:C009695
DrugEpinephrine

ADRA1D ADRA1B ADRA1A

4.81e-0681023DB00668
DrugOxymetazoline

ADRA1D ADRA1B ADRA1A

4.81e-0681023ctd:D010109
Drugtiodazosin

ADRA1D ADRA1B ADRA1A

4.81e-0681023CID000060891
DrugSertindole

ADRA1D ADRA1B ADRA1A

4.81e-0681023DB06144
Drugdibenamine

ZEB1 ADRA1D ADRA1B ADRA1A

5.26e-06261024CID000005820
Drugalpha-methyldopamine

ADRA1B ADRA1A SEMA6A HDC

5.26e-06261024CID000017005
Drugguanadrel

ADRA1D ADRA1B ADRA1A

7.19e-0691023CID000038521
DrugSB-273779

ADRA1D ADRA1B ADRA1A

7.19e-0691023CID005311133
Drugdapiprazole

ADRA1D ADRA1B ADRA1A

7.19e-0691023CID003033538
Drugp-menthane

ADRA1D ADRA1B ADRA1A

7.19e-0691023CID000007459
Drugadrafinil

ADRA1D ADRA1B ADRA1A

7.19e-0691023CID003033226
DrugNorepinephrine

ADRA1D ADRA1B ADRA1A

1.02e-05101023DB00368
Drugtrimazosin

ADRA1D ADRA1B ADRA1A

1.02e-05101023CID000037264
DrugL-659,066

ADRA1D ADRA1B ADRA1A

1.02e-05101023CID000163952
DrugErgotamine

ADRA1D ADRA1B ADRA1A

1.02e-05101023DB00696
Drugazapetine

ADRA1D ADRA1B ADRA1A

1.02e-05101023CID000008966
DrugDroxidopa

ADRA1D ADRA1B ADRA1A

1.02e-05101023DB06262
DrugDO 710

ADRA1D ADRA1B ADRA1A

1.02e-05101023CID003084985
Drugbethanidine

ADRA1D ADRA1B ADRA1A

1.86e-05121023CID000002368
DrugSZL-49

ADRA1D ADRA1B ADRA1A

1.86e-05121023CID000004892
DrugSt-1913

ADRA1B ADRA1A

1.99e-0521022CID000123528
DrugNeldazosin

ADRA1B ADRA1A

1.99e-0521022CID000065908
DrugDL-028

ADRA1B ADRA1A

1.99e-0521022CID005487531
Drugquinazosin

ADRA1B ADRA1A

1.99e-0521022CID000027486
Drughydroxyphenacetyl aminoclonidine

ADRA1B ADRA1A

1.99e-0521022CID000173558
DrugMidodrine

ADRA1B ADRA1A

1.99e-0521022DB00211
Drugsulfonterol

ADRA1B ADRA1A

1.99e-0521022CID000170372
DrugAC1L27FT

ADRA1B ADRA1A

1.99e-0521022CID000016192
Drugpaveril

ADRA1B ADRA1A

1.99e-0521022CID000006855
Drugtolazine

ADRA1B ADRA1A

1.99e-0521022CID000101252
Drugpiclonidine

ADRA1B ADRA1A

1.99e-0521022CID000068914
DrugLidanserin

ADRA1B ADRA1A

1.99e-0521022CID000068919
DrugFCE 22716

ADRA1B ADRA1A

1.99e-0521022CID000125720
DrugSKF 101253

ADRA1B ADRA1A

1.99e-0521022CID000135152
DrugASL-7022

ADRA1B ADRA1A

1.99e-0521022CID000173406
Drughoquizil

ADRA1B ADRA1A

1.99e-0521022CID000030690
DrugMethoxamine

ADRA1B ADRA1A

1.99e-0521022DB00723
DrugPrestwick_774

ADRA1B ADRA1A

1.99e-0521022CID006420011
Drugcompound 44-549

ADRA1B ADRA1A

1.99e-0521022CID000191431
Drug5-dembs

ADRA1B ADRA1A

1.99e-0521022CID000130379
Druglevomepromazine sulfoxide

ADRA1B ADRA1A

1.99e-0521022CID000165566
DrugR 56

ADRA1B ADRA1A

1.99e-0521022CID009578362
Drugdihydrolysergic acid amide

ADRA1B ADRA1A

1.99e-0521022CID000151000
DrugSt-404

ADRA1B ADRA1A

1.99e-0521022CID000191786
DrugAC1MBW4N

ADRA1B ADRA1A

1.99e-0521022CID002732234
DrugMyordil

ADRA1B ADRA1A

1.99e-0521022CID000011282
Drug5-cfmbs

ADRA1B ADRA1A

1.99e-0521022CID000183818
DrugIK29

ADRA1B ADRA1A

1.99e-0521022CID000183825
Drugpyrroxan

ADRA1B ADRA1A

1.99e-0521022CID000036302
Drugdihydroergonine

ADRA1B ADRA1A

1.99e-0521022CID000193205
DrugIndoramin

ADRA1B ADRA1A

1.99e-0521022ctd:D007217
Drugpenta-O-ethylquercetin

ADRA1B ADRA1A

1.99e-0521022CID000133942
Drugsarpogrelate

ADRA1D ADRA1B ADRA1A SORL1

2.24e-05371024ctd:C064294
Drugpractolol

ADRA1D ADRA1B ADRA1A EDAR

2.24e-05371024CID000004883
DrugNSC196867

ADRA1D ADRA1B ADRA1A

2.42e-05131023CID000003982
Drugindoramin

ADRA1D ADRA1B ADRA1A

2.42e-05131023CID000033625
Drugoxymetazoline

CHRNA9 ADRA1D ADRA1B ADRA1A CHRNA10

2.83e-05791025CID000004636
DrugDMSe

FLNA COL12A1 ADGRE2 EDAR COL14A1 SEMA6A

2.89e-051321026CID000020796
Drugchlorpromazine hydrochloride; Up 200; 1uM; HL60; HT_HG-U133A

DMXL2 TRPV1 ADGRE2 ATP10A SVEP1 SPIDR NOTCH2

2.91e-0519610271158_UP
DrugEstriol [50-27-1]; Up 200; 13.8uM; PC3; HT_HG-U133A

ADGRE2 ATP10A FBN2 EGF VCAN ZFHX2 NOTCH2

3.01e-0519710275866_UP
DrugNomifensine maleate [32795-47-4]; Up 200; 11.2uM; MCF7; HT_HG-U133A

TNPO2 CPD SVEP1 FANCA ADRA1A IGFALS KRTAP9-9

3.01e-0519710277217_UP
Drugderiglidole

ADRA1D ADRA1B ADRA1A

3.07e-05141023CID000065945
Drugpropiomazine

ADRA1D ADRA1B ADRA1A

3.07e-05141023CID000004940
Diseaseconnective tissue disease (implicated_via_orthology)

FBN1 FBN2 FBN3

3.23e-083953DOID:65 (implicated_via_orthology)
Diseaseintellectual developmental disorder with hypotonia, impaired speech, and dysmorphic facies (implicated_via_orthology)

TNPO1 TNPO2

1.03e-052952DOID:0081262 (implicated_via_orthology)
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

FLNA FBN1 FBN2 VCAN

2.62e-0553954C4707243
DiseaseBicuspid aortic valve

HMCN2 MUC4

3.07e-053952HP_0001647
DiseaseMalignant neoplasm of breast

FLNA ZEB1 B4GAT1 DTX3L DLL1 RSPO3 FASN ADRA1A EGF STPG1 ELAPOR1 NOTCH2 SORL1

4.02e-0510749513C0006142
Diseasepolycystic ovary syndrome (biomarker_via_orthology)

ADRA1D ADRA1B ADRA1A

4.12e-0521953DOID:11612 (biomarker_via_orthology)
Diseasescoliosis (is_implicated_in)

FBN1 FBN2

6.13e-054952DOID:0060249 (is_implicated_in)
Diseaseresponse to hydroxyurea

ADRA1D ADRA1A

6.13e-054952GO_0072710
Diseaselevulinate 4-oxovalerate measurement

ADRA1D ADRA1A

6.13e-054952EFO_0021024
Diseasecortical surface area measurement

ZBTB16 ZAN ZNF423 SKIDA1 PLXNB2 SVEP1 RSPO3 SLIT2 FBN1 FBN2 VCAN SEMA6A ADGRL2 FBN3

1.01e-0413459514EFO_0010736
DiseaseMetaplasia

RAG2 EGF

1.02e-045952C0025568
Diseaseresponse to angiotensin receptor blocker

BCAS3 RSPO3 DUSP16

1.23e-0430953EFO_0010735
DiseaseFever, Diarrhea, response to sulfasalazine

ADRA1D ADRA1A

1.53e-046952EFO_0008324, HP_0001945, HP_0002014
Diseasebirth measurement, spontaneous preterm birth

ADGRL2 SORL1

2.13e-047952EFO_0006917, EFO_0006921
DiseaseNEPHRONOPHTHISIS 2

ZNF423 NEK8

2.84e-048952C1865872
Diseaseprimary ovarian insufficiency (is_implicated_in)

FANCA TP63

2.84e-048952DOID:5426 (is_implicated_in)
DiseaseMammary Carcinoma, Human

FLNA ZEB1 B4GAT1 DLL1 RSPO3 FASN EGF NOTCH2

2.99e-04525958C4704874
DiseaseMammary Neoplasms, Human

FLNA ZEB1 B4GAT1 DLL1 RSPO3 FASN EGF NOTCH2

2.99e-04525958C1257931
DiseaseMammary Neoplasms

FLNA ZEB1 B4GAT1 DLL1 RSPO3 FASN EGF NOTCH2

3.06e-04527958C1458155
Diseasebrain connectivity measurement

SKIDA1 FANCA PIAS4 RSPO3 SLIT2 VCAN SNX31

3.17e-04400957EFO_0005210
DiseaseNeoplasm Invasiveness

ZEB1 ZBTB16 EGF NOTCH2 SORL1

3.29e-04184955C0027626
DiseaseBreast Carcinoma

FLNA ZEB1 B4GAT1 DLL1 RSPO3 FASN EGF NOTCH2

3.52e-04538958C0678222
Diseasemitral valve prolapse (is_implicated_in)

FLNA FBN1

3.64e-049952DOID:988 (is_implicated_in)
Diseasegrey matter volume measurement

ADRA1D ADRA1A ADGRL2

3.89e-0444953EFO_0005420
Diseaseserum urea measurement

TNPO1 FANCA RSPO3 ADGRL2 SORL1

4.29e-04195955EFO_0009795
Diseasedimethylglycine measurement

FANCA ZNF804B ADGRL2

4.44e-0446953EFO_0010476
Diseaseblood urea nitrogen measurement

TNPO1 BCAS3 FANCA RSPO3 WDR90 ADGRL2 SORL1

6.55e-04452957EFO_0004741
DiseaseTinnitus, response to cisplatin

ADRA1D ADRA1A

1.05e-0315952GO_0072718, HP_0000360
DiseaseNeoplastic Cell Transformation

ZEB1 CHRNA9 EGF TP63

1.08e-03139954C0007621
DiseaseLiver carcinoma

RSPO3 SLIT2 FASN ADRA1A IGFALS FBXL18 EGF

1.28e-03507957C2239176
DiseaseS-adenosylhomocysteine measurement

ADRA1D ADRA1A

1.35e-0317952EFO_0010531
Diseaseamino acid measurement

SLIT2 ADRA1D ADRA1A FBLN2 VCAN MCM9 COL14A1 ADGRL2

1.57e-03678958EFO_0005134
Diseaseabnormal paneth cell measurement

ZBTB16 ADRA1D

1.69e-0319952EFO_0007963
Diseaseovulation

TMEM150B FANCA

1.69e-0319952GO_0030728
DiseaseX-24309 measurement

ADRA1D ADRA1A

1.88e-0320952EFO_0800872
Diseasegut microbiome measurement, bone density

ZEB1 COL12A1 ADGRL2

2.07e-0378953EFO_0003923, EFO_0007874
Diseaserenal system measurement, blood urea nitrogen measurement

BCAS3 RSPO3

2.27e-0322952EFO_0004741, EFO_0004742
Diseasegamma-glutamylglutamine measurement

TNPO1 SLIT2

2.27e-0322952EFO_0021138
DiseaseEpilepsy, Benign Psychomotor, Childhood

TRPV1 SLIT2

2.48e-0323952C0393672
DiseaseEpilepsy, Lateral Temporal

TRPV1 SLIT2

2.48e-0323952C0393682
DiseaseUncinate Epilepsy

TRPV1 SLIT2

2.48e-0323952C0014558
DiseaseEpilepsy, Temporal Lobe

TRPV1 SLIT2

2.48e-0323952C0014556
Diseasetemperament and character inventory

FBN2 ADGRL2

2.70e-0324952EFO_0004825
DiseaseKidney Diseases

ADRA1B EGF NEK8

2.91e-0388953C0022658
Diseasewhite matter hyperintensity measurement

ZAN ADRA1D ADRA1A VCAN SNX31

2.97e-03302955EFO_0005665
Diseasebrain cancer (implicated_via_orthology)

INSM1 NOTCH2

3.17e-0326952DOID:1319 (implicated_via_orthology)
Diseaseisthmus cingulate cortex volume measurement

ADRA1D ADRA1A

3.17e-0326952EFO_0010310
DiseaseEndogenous Hyperinsulinism

FANCA FBN1

3.17e-0326952C1257963
DiseaseExogenous Hyperinsulinism

FANCA FBN1

3.17e-0326952C1257964
DiseaseCompensatory Hyperinsulinemia

FANCA FBN1

3.17e-0326952C1257965
Diseasenevus count, cutaneous melanoma

PLXNB2 FANCA NOTCH2

3.20e-0391953EFO_0000389, EFO_0004632

Protein segments in the cluster

PeptideGeneStartEntry
YGCCSEPYPDVTFTL

CHRNA10

216

Q9GZZ6
TEYCNGDLPYCLPDT

ADAM5

181

Q6NVV9
PTETSYVCTCVPGYS

VCAN

3106

P13611
PFYYGLCTPCQAPTN

B4GAT1

286

O43505
SYDCVCSPGYEPVSG

ADGRE2

91

Q9UHX3
YLNSCINPIIYPCSS

ADRA1A

316

P35348
GSCLPVFSTLPFAYC

COL4A4

1511

P53420
CQPPAYTYNNITCAS

IGFALS

571

P35858
QYECVPYIFVCPGTL

ADGRL2

126

O95490
LGYFNSCLNPIIYPC

ADRA1B

336

P35368
PTCFILCGNFSSAPY

POLE2

316

P56282
VKNVISYGCCSEPYP

CHRNA9

211

Q9UGM1
SYGCCSEPYPDVTFT

CHRNA9

216

Q9UGM1
YPVCLAPYLVVTTCS

DMXL2

1006

Q8TDJ6
PTPSSYRCECNVGYT

FBN3

426

Q75N90
GSSGTSPPYCCVDLY

BCAS3

156

Q9H6U6
IPSYCLGAYCNSPSA

DMXL1

746

Q9Y485
LIYNASCATCYPPSN

ATP10A

1246

O60312
SCYLPPLRYPATCTF

RAG2

66

P55895
GQYCDSLYVPCAPSP

NOTCH2NLA

176

Q7Z3S9
FYSVPSFPECSSQCG

HDC

636

P19113
VYSPQSGFTCVSPCS

MUC4

5311

Q99102
PYYSCQCAPPFSGSR

NOTCH2

1396

Q04721
PSPLNYYNFPKSCCT

METAP1

181

P53582
SYQCVDTPCPATYRQ

HMCN2

4926

Q8NDA2
YGMVCYSCLLAPPNT

EDAR

131

Q9UNE0
PCPYGSYSNGSDCTR

ELAPOR1

396

Q6UXG2
VSCLYTLGYPPAQAQ

DYNC2I2

146

Q96EX3
YYESPSTQCLLCSSP

HMGXB3

741

Q12766
VPGSYQCACPEQGYT

FBLN2

1001

P98095
SYPTCTQCRDSQDPY

PLXNB2

471

O15031
SENPCSLYSSVCYSP

KBTBD2

276

Q8IY47
YTVVGTPCYISPELC

NEK8

161

Q86SG6
TTLYLVPCLNDCGPY

PGAP6

491

Q9HCN3
QPCLALLCSPYYSGN

MPND

381

Q8N594
VYCQGPTPNCSIYEP

PLA2G2F

136

Q9BZM2
GQYCDSLYVPCAPSP

NOTCH2NLC

176

P0DPK4
YCLYPILESQVCAPS

DPRX

161

A6NFQ7
YTSECFPCKPGTFSN

ELAPOR2

286

A8MWY0
SAYPPNGVECYSCVG

LYPD3

131

O95274
CYAPLNPDNTSLYDC

NPC1L1

471

Q9UHC9
SRCATLQYCPDPYIQ

TP63

6

Q9H3D4
QTDSGPYCVPCYDNT

FHL3

21

Q13643
PGYCDSSQCASIPYN

COL12A1

3041

Q99715
SYKPICPTCQTSYGI

DTX3L

591

Q8TDB6
GSYYCTCPVGFVLLP

EGF

376

P01133
LENSYSCTCPPGFYG

DLL1

346

O00548
TCRVTYCPTEPGNYI

FLNA

2101

P21333
NTVSSYFCKCPPGFY

FBN1

306

P35555
PGYCDPSSCSAYGVR

COL14A1

1756

Q05707
DKIPPSLYSTYCQAC

FANCA

611

O15360
AYSCSQLPTCGDQVY

DUSP16

581

Q9BY84
PEITVYTSCCYFPSA

CPD

1176

O75976
YTSCCYFPSAARLPS

CPD

1181

O75976
TITGEYCCSCAPPYR

CALHM4

76

Q5JW98
SYECTTDCPNLQPYF

CRYGB

16

P07316
AGPVDLCTYPKYCTV

BRWD1

1186

Q9NSI6
SCQSPCYRPAYGSTF

KRTAP13-2

156

Q52LG2
YYPTTVCLPGCLNQS

KRTAP9-2

121

Q9BYQ4
YYPTTVCLPGCLNQS

KRTAP9-4

106

Q9BYQ2
YYPTTVCLPGCLNQS

KRTAP9-9

101

Q9BYP9
PCFIPSYVSPLCYIS

KRTAP24-1

181

Q3LI83
SYVSPLCYISNSCQP

KRTAP24-1

186

Q3LI83
NTVGSYFCVCPRGYV

FBN2

336

P35556
NPCETCPPVNSTEYY

FBN2

1616

P35556
CPPVNSTEYYTLCPG

FBN2

1621

P35556
GTCYNTLGNYTCICP

FBN2

1706

P35556
PTCPGAQLCTVYYAS

FASN

1556

P49327
ENCYNTPGSYVCVCP

CRELD2

306

Q6UXH1
SCPCSYPTEVAYSTA

ISM1

321

B1AKI9
YGCQAPTICFVYQDP

DDB1

171

Q16531
CKYCPATFYSSPGLT

INSM1

471

Q01101
SQPYECVFTGTCYPN

CFAP221

246

Q4G0U5
EQYYTFCRPSSCPSL

MCM9

161

Q9NXL9
PSTCLPNYYRCSSGT

SORL1

1416

Q92673
YISICGSFPPQSCIF

TMEM150B

41

A6NC51
PTEYCGTFCYPNVSQ

OGA

216

O60502
FTPSYGVVPCCTSLE

FBXL18

181

Q96ME1
PVYCPASLGSCFAEI

SKIDA1

531

Q1XH10
LQYECTACPSGTYKP

SVEP1

316

Q4LDE5
YLQLDPCTCDYPESG

SNX31

271

Q8N9S9
NDINECTPPYSVYCG

ADGRE3

66

Q9BY15
CTPPYSVYCGFNAVC

ADGRE3

71

Q9BY15
GYFNSCVNPLIYPCS

ADRA1D

391

P25100
SYCTLPPMYPGSSTC

TULP4

1236

Q9NRJ4
VCSLSHQQPPTSCYY

RNASE13

111

Q5GAN3
TYKGLPCPYASCILA

TMEM269

141

A0A1B0GVZ9
LCYGAPPLLYCGTSS

WDR90

1306

Q96KV7
YPCDLCGKSYSAPQS

ZNF865

441

P0CJ78
KTEPCISYGCNPLYF

ZNF804B

466

A4D1E1
GASPYQCTICTEYCP

ZBTB16

626

Q05516
QTTVYCCPYCSFLSP

ZFHX2

976

Q9C0A1
LPYCGPNIIDSYFCD

OR4E2

166

Q8NGC2
PPSSYILSNNGYCTV

PGC

331

P20142
ISFYQACCLPGVIPY

SLC37A3

281

Q8NCC5
ACCLPGVIPYSLAYA

SLC37A3

286

Q8NCC5
CRPPDSSYNSLYSTC

TRPV1

621

Q8NER1
IPSGSCPVILNTYFC

SPIDR

371

Q14159
ETPAPNYYNASVSCC

STPG1

146

Q5TH74
STPYNSIPGSAVCAY

SEMA6A

316

Q9H2E6
SGFLPYCEPVYQRCV

TNPO2

596

O14787
CLSSCPSGYYGTRYP

RSPO3

76

Q9BXY4
GINNYTCLCPPEYTG

SLIT2

1016

O94813
PEPGLSQYICYVFQC

TBC1D4

406

O60343
QSGFLPYCEPVYQRC

TNPO1

606

Q92973
CYSDTSCPQEDQYPP

PIAS4

196

Q8N2W9
VAPYFSYPVALSCKC

TSHB

91

P01222
GTPDAFSQLLTCPYC

ZEB1

161

P37275
QTYVKCPAPCQTTYV

XP32

86

Q5T750
GASPCQSYYVQAPAS

XP32

136

Q5T750
YCVTDPCSAPCSTSY

XP32

156

Q5T750
EVYSCPYCTNSPIFG

ZNF423

561

Q2M1K9
VPEGLCISVPCSFSY

SIGLEC10

31

Q96LC7
CPAYSSYTNCLPSCS

ZAN

2211

Q9Y493
VGAPSVCSSCGQSYY

ZNF787

341

Q6DD87