Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR8A1 OR5AC2 OR5AK2 OR2T27 OR51Q1 GPR34 OR51I2 OR5AN1 TAS1R2 OR56A3 OR13G1 MRGPRX2 OR1C1 OR5AK3P OR4D11 OR8U3 OR2L13 EDNRA EDNRB OR8U9 OPRM1	6.37e-12	884	75	21	GO:0004930
GeneOntologyMolecularFunction	olfactory receptor activity	OR8A1 OR5AC2 OR5AK2 OR2T27 OR51Q1 OR51I2 OR5AN1 OR56A3 OR13G1 OR1C1 OR5AK3P OR4D11 OR8U3 OR2L13 OR8U9	5.64e-11	431	75	15	GO:0004984
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR8A1 ABCA1 OR5AC2 OR5AK2 OR2T27 IL1RAPL2 OR51Q1 GPR34 OR51I2 OR5AN1 HTR3E TAS1R2 OR56A3 OR13G1 MRGPRX2 OR1C1 OR5AK3P OR4D11 OR8U3 OR2L13 EDNRA EDNRB OR8U9 OPRM1	6.45e-11	1353	75	24	GO:0004888
GeneOntologyMolecularFunction	odorant binding	OR8A1 OR5AC2 OR5AK2 OR5AN1 OR13G1 OR5AK3P OR8U3 OR8U9	2.53e-08	127	75	8	GO:0005549
GeneOntologyMolecularFunction	NADH oxidase H202-forming activity	DUOX1 DUOX2	1.39e-05	2	75	2	GO:0106293
GeneOntologyMolecularFunction	endothelin receptor activity	EDNRA EDNRB	4.17e-05	3	75	2	GO:0004962
GeneOntologyMolecularFunction	NADPH oxidase H202-forming activity	DUOX1 DUOX2	1.38e-04	5	75	2	GO:0106294
GeneOntologyMolecularFunction	NAD(P)H oxidase H2O2-forming activity	DUOX1 DUOX2	8.97e-04	12	75	2	GO:0016174
GeneOntologyMolecularFunction	superoxide-generating NAD(P)H oxidase activity	DUOX1 DUOX2	8.97e-04	12	75	2	GO:0016175
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR8A1 OR5AC2 OR5AK2 OR2T27 OR51Q1 OR51I2 OR5AN1 TAS1R2 OR56A3 OR13G1 OR1C1 OR5AK3P OR4D11 OR8U3 OR2L13 OR8U9	2.02e-11	485	76	16	GO:0050907
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR8A1 OR5AC2 OR5AK2 OR2T27 OR51Q1 OR51I2 OR5AN1 OR56A3 OR13G1 OR1C1 OR5AK3P OR4D11 OR8U3 OR2L13 OR8U9	4.55e-11	432	76	15	GO:0050911
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR8A1 OR5AC2 OR5AK2 OR2T27 OR51Q1 OR51I2 OR5AN1 TAS1R2 OR56A3 OR13G1 OR1C1 OR5AK3P OR4D11 OR8U3 OR2L13 OR8U9	6.38e-11	524	76	16	GO:0009593
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR8A1 OR5AC2 OR5AK2 OR2T27 OR51Q1 OR51I2 OR5AN1 TAS1R2 OR56A3 OR13G1 OR1C1 OR5AK3P OR4D11 OR8U3 OR2L13 OR8U9	1.20e-10	547	76	16	GO:0007606
GeneOntologyBiologicalProcess	sensory perception of smell	OR8A1 OR5AC2 OR5AK2 OR2T27 OR51Q1 OR51I2 OR5AN1 OR56A3 OR13G1 OR1C1 OR5AK3P OR4D11 OR8U3 OR2L13 OR8U9	1.27e-10	465	76	15	GO:0007608
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR8A1 OR5AC2 OR5AK2 OR2T27 OR51Q1 OR51I2 OR5AN1 TAS1R2 OR56A3 OR13G1 OR1C1 OR5AK3P OR4D11 OR8U3 OR2L13 OR8U9	2.98e-10	582	76	16	GO:0050906
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR8A1 ABCA1 OR5AC2 OR5AK2 OR2T27 OR51Q1 GPR34 OR51I2 OR5AN1 TAS1R2 OR56A3 OR13G1 MRGPRX2 OR1C1 OR5AK3P OR4D11 OR8U3 OR2L13 EDNRA EDNRB OR8U9 OPRM1	3.29e-09	1395	76	22	GO:0007186
GeneOntologyBiologicalProcess	detection of stimulus	OR8A1 OR5AC2 OR5AK2 OR2T27 OR51Q1 OR51I2 OR5AN1 TAS1R2 OR56A3 OR13G1 OR1C1 OR5AK3P OR4D11 OR8U3 OR2L13 OR8U9	6.58e-09	722	76	16	GO:0051606
GeneOntologyBiologicalProcess	sensory perception	OR8A1 OR5AC2 OR5AK2 OR2T27 OR51Q1 OR51I2 OR5AN1 TAS1R2 OR56A3 OR13G1 MRGPRX2 OR1C1 OR5AK3P OR4D11 OR8U3 WDR1 OR2L13 OR8U9 OPRM1	7.72e-09	1072	76	19	GO:0007600
GeneOntologyBiologicalProcess	response to nitrogen compound	DUOX1 ABCA1 MTHFR RPS6KB1 PRKAA2 HTR3E PER1 DUOX2 MRGPRX2 REG1A GCK ARHGEF2 EDNRA EDNRB DHX9 OPRM1	1.28e-05	1272	76	16	GO:1901698
GeneOntologyBiologicalProcess	cuticle development	DUOX1 DUOX2	4.01e-05	3	76	2	GO:0042335
GeneOntologyBiologicalProcess	organic hydroxy compound metabolic process	DUOX1 ABCA1 DHRS7 PRKAA2 DUOX2 CACNA1H TKTL1 CUBN EDNRA EDNRB	1.18e-04	641	76	10	GO:1901615
GeneOntologyBiologicalProcess	positive regulation of peptidyl-lysine acetylation	DIP2A PRKAA2	2.78e-04	7	76	2	GO:2000758
MousePheno	impaired glucose tolerance	TANC2 KIFAP3 RPS6KB1 PRKAA2 PAM DEPDC5 GCK TTC38 VPS13B CES2	6.20e-06	480	50	10	MP:0005293
Domain	GPCR_Rhodpsn_7TM	OR8A1 OR5AC2 OR5AK2 OR2T27 OR51Q1 GPR34 OR51I2 OR5AN1 OR56A3 OR13G1 MRGPRX2 OR1C1 OR4D11 OR8U3 OR2L13 EDNRA EDNRB OR8U9 OPRM1	1.18e-11	670	75	19	IPR017452
Domain	7tm_1	OR8A1 OR5AC2 OR5AK2 OR2T27 OR51Q1 GPR34 OR51I2 OR5AN1 OR56A3 OR13G1 MRGPRX2 OR1C1 OR4D11 OR8U3 OR2L13 EDNRA EDNRB OR8U9 OPRM1	1.41e-11	677	75	19	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR8A1 OR5AC2 OR5AK2 OR2T27 OR51Q1 GPR34 OR51I2 OR5AN1 OR56A3 OR13G1 MRGPRX2 OR1C1 OR4D11 OR8U3 OR2L13 EDNRA EDNRB OR8U9 OPRM1	1.73e-11	685	75	19	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR8A1 OR5AC2 OR5AK2 OR2T27 OR51Q1 GPR34 OR51I2 OR5AN1 OR56A3 OR13G1 MRGPRX2 OR1C1 OR4D11 OR8U3 OR2L13 EDNRA EDNRB OR8U9 OPRM1	2.01e-11	691	75	19	PS50262
Domain	GPCR_Rhodpsn	OR8A1 OR5AC2 OR5AK2 OR2T27 OR51Q1 GPR34 OR51I2 OR5AN1 OR56A3 OR13G1 MRGPRX2 OR1C1 OR4D11 OR8U3 OR2L13 EDNRA EDNRB OR8U9 OPRM1	2.06e-11	692	75	19	IPR000276
Domain	Olfact_rcpt	OR8A1 OR5AC2 OR5AK2 OR2T27 OR51Q1 OR51I2 OR5AN1 OR56A3 OR13G1 OR1C1 OR4D11 OR8U3 OR2L13 OR8U9	4.63e-10	393	75	14	IPR000725
Domain	Endthln_rcpt	EDNRA EDNRB	1.59e-05	2	75	2	IPR000499
Domain	DUOX1	DUOX1 DUOX2	1.59e-05	2	75	2	IPR029595
Domain	NAD_binding_6	DUOX1 DUOX2	3.30e-04	7	75	2	PF08030
Domain	FAD_binding_8	DUOX1 DUOX2	3.30e-04	7	75	2	PF08022
Domain	FAD-bd_8	DUOX1 DUOX2	3.30e-04	7	75	2	IPR013112
Domain	Fe_red_NAD-bd_6	DUOX1 DUOX2	3.30e-04	7	75	2	IPR013121
Domain	Haem_peroxidase	DUOX1 DUOX2	7.01e-04	10	75	2	IPR010255
Domain	An_peroxidase	DUOX1 DUOX2	7.01e-04	10	75	2	PF03098
Domain	PEROXIDASE_3	DUOX1 DUOX2	7.01e-04	10	75	2	PS50292
Domain	Haem_peroxidase_animal	DUOX1 DUOX2	7.01e-04	10	75	2	IPR019791
Domain	-	DUOX1 DUOX2	7.01e-04	10	75	2	1.10.640.10
Domain	Ferric_reduct	DUOX1 DUOX2	1.02e-03	12	75	2	PF01794
Domain	Fe3_Rdtase_TM_dom	DUOX1 DUOX2	1.02e-03	12	75	2	IPR013130
Domain	Fd_Rdtase_FAD-bd	DUOX1 DUOX2	2.60e-03	19	75	2	IPR017927
Domain	FAD_FR	DUOX1 DUOX2	2.60e-03	19	75	2	PS51384
Domain	Riboflavin_synthase-like_b-brl	DUOX1 DUOX2	2.60e-03	19	75	2	IPR017938
Domain	Longin-like_dom	COPZ2 SEC22A	5.62e-03	28	75	2	IPR011012
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR8A1 OR5AC2 OR5AK2 OR2T27 OR51Q1 OR51I2 OR5AN1 OR56A3 OR13G1 OR1C1 OR4D11 OR8U3 OR2L13 OR8U9	3.15e-09	417	63	14	M4072
Pathway	KEGG_OLFACTORY_TRANSDUCTION	OR8A1 OR5AC2 OR5AK2 OR2T27 OR51Q1 OR51I2 OR5AN1 OR56A3 OR13G1 OR1C1 OR4D11 OR8U3 OR2L13	1.32e-08	389	63	13	M14091
Pathway	REACTOME_SENSORY_PERCEPTION	OR8A1 OR5AC2 OR5AK2 OR2T27 OR51Q1 OR51I2 OR5AN1 TAS1R2 OR56A3 OR13G1 OR1C1 OR4D11 OR8U3 OR2L13 OR8U9	9.02e-08	636	63	15	M41834
Pathway	WP_THYROXINE_THYROID_HORMONE_PRODUCTION	DUOX1 PRKAA2 DUOX2	1.82e-04	25	63	3	M39353
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR8A1 OR5AK2 OR51Q1 OR51I2 OR5AN1 OR56A3 OR13G1 OR5AK3P OR4D11 OR8U3 OR2L13	2.49e-10	340	77	11	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR8A1 OR5AK2 OR51Q1 OR51I2 OR5AN1 OR56A3 OR13G1 OR5AK3P OR4D11 OR8U3 OR2L13	2.49e-10	340	77	11	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR8A1 OR5AK2 OR51Q1 OR51I2 OR5AN1 OR56A3 OR13G1 OR5AK3P OR4D11 OR8U3 OR2L13	2.74e-10	343	77	11	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR8A1 OR5AK2 OR51Q1 OR51I2 OR5AN1 OR56A3 OR13G1 OR5AK3P OR4D11 OR8U3 OR2L13	3.00e-10	346	77	11	14611657
Pubmed	The human olfactory receptor gene family.	OR8A1 OR5AK2 OR2T27 OR51I2 OR5AN1 OR56A3 OR13G1 OR1C1 OR4D11 OR8U3	3.29e-07	541	77	10	14983052
Pubmed	Genetic risk factors for hepatopulmonary syndrome in patients with advanced liver disease.	DUOX1 MTHFR DUOX2 EDNRA EDNRB	2.19e-06	94	77	5	20346360
Pubmed	Digenic DUOX1 and DUOX2 Mutations in Cases With Congenital Hypothyroidism.	DUOX1 DUOX2	4.84e-06	2	77	2	28633507
Pubmed	Endothelin receptor heteromerization inhibits β-arrestin function in HEK293 cells.	EDNRA EDNRB	4.84e-06	2	77	2	32744876
Pubmed	Identification of a novel role for endothelins within the oviduct.	EDNRA EDNRB	4.84e-06	2	77	2	20357223
Pubmed	Expression of endothelin receptors in frog, chicken, mouse and human pigment cells.	EDNRA EDNRB	4.84e-06	2	77	2	16962346
Pubmed	The expression of endothelin type A and B receptors in the lateral wall of the mouse cochlea.	EDNRA EDNRB	4.84e-06	2	77	2	17607529
Pubmed	Reactive oxygen species regulate the levels of dual oxidase (Duox1-2) in human neuroblastoma cells.	DUOX1 DUOX2	4.84e-06	2	77	2	22523549
Pubmed	Expression of dual oxidases and secreted cytokines in chronic rhinosinusitis.	DUOX1 DUOX2	4.84e-06	2	77	2	23281318
Pubmed	Expression of endothelin receptor subtypes in bronchial tumors.	EDNRA EDNRB	4.84e-06	2	77	2	20043107
Pubmed	Modulation of endothelin receptors in the failing right ventricle of the heart and vasculature of the lung in human pulmonary arterial hypertension.	EDNRA EDNRB	4.84e-06	2	77	2	24582810
Pubmed	Dual oxidase 1 and NADPH oxidase 2 exert favorable effects in cervical cancer patients by activating immune response.	DUOX1 DUOX2	4.84e-06	2	77	2	31706280
Pubmed	Functional diversity of endothelin pathways in human lung fibroblasts may be based on structural diversity of the endothelin receptors.	EDNRA EDNRB	4.84e-06	2	77	2	14636059
Pubmed	Endothelin ETA and ETB receptor expression in the human trigeminal ganglion.	EDNRA EDNRB	4.84e-06	2	77	2	16816835
Pubmed	Association between migraine and endothelin type A receptor (ETA -231 A/G) gene polymorphism.	EDNRA EDNRB	4.84e-06	2	77	2	11376172
Pubmed	Molecular characterization and regulation of the human endothelin receptors.	EDNRA EDNRB	4.84e-06	2	77	2	8440682
Pubmed	Dual oxidase-2 has an intrinsic Ca2+-dependent H2O2-generating activity.	DUOX1 DUOX2	4.84e-06	2	77	2	15972824
Pubmed	Altered expression and signal transduction of endothelin-1 receptors in heritable and idiopathic pulmonary arterial hypertension.	EDNRA EDNRB	4.84e-06	2	77	2	22688668
Pubmed	ETA and ETB receptors are expressed in vascular adventitial fibroblasts.	EDNRA EDNRB	4.84e-06	2	77	2	21949113
Pubmed	Endothelin antagonism in portal hypertensive mice: implications for endothelin receptor-specific signaling in liver disease.	EDNRA EDNRB	4.84e-06	2	77	2	19299580
Pubmed	Conserved cysteine residues provide a protein-protein interaction surface in dual oxidase (DUOX) proteins.	DUOX1 DUOX2	4.84e-06	2	77	2	23362256
Pubmed	Activation of dual oxidases Duox1 and Duox2: differential regulation mediated by camp-dependent protein kinase and protein kinase C-dependent phosphorylation.	DUOX1 DUOX2	4.84e-06	2	77	2	19144650
Pubmed	Elevation of blood pressure by genetic and pharmacological disruption of the ETB receptor in mice.	EDNRA EDNRB	4.84e-06	2	77	2	10198387
Pubmed	Increased gene expression and production of murine endothelin receptors after birth.	EDNRA EDNRB	4.84e-06	2	77	2	12763050
Pubmed	[Molecular cloning of human endothelin receptors and their expression in vascular endothelial cells and smooth muscle cells].	EDNRA EDNRB	4.84e-06	2	77	2	1291713
Pubmed	Down-regulation of ETA receptors in ETB receptor-deficient mice.	EDNRA EDNRB	4.84e-06	2	77	2	15838300
Pubmed	Real-time polymerase chain reaction quantification of gene expression levels of murine endothelin-A and endothelin-B receptors: gene expression profiles by the standard curve method.	EDNRA EDNRB	4.84e-06	2	77	2	15838311
Pubmed	Comparison of endothelin receptors in normal versus cirrhotic human liver and in the liver from endothelial cell-specific ETB knockout mice.	EDNRA EDNRB	4.84e-06	2	77	2	22365955
Pubmed	Expression of nicotinamide adenine dinucleotide phosphate oxidase flavoprotein DUOX genes and proteins in human papillary and follicular thyroid carcinomas.	DUOX1 DUOX2	4.84e-06	2	77	2	11762710
Pubmed	Characterization of ThOX proteins as components of the thyroid H(2)O(2)-generating system.	DUOX1 DUOX2	4.84e-06	2	77	2	11822874
Pubmed	Endothelin receptor pharmacology and function in the mouse: comparison with rat and man.	EDNRA EDNRB	4.84e-06	2	77	2	15838332
Pubmed	Comparison of endothelin-A and endothelin-B receptor distribution visualized by radioligand binding versus immunocytochemical localization using subtype selective antisera.	EDNRA EDNRB	4.84e-06	2	77	2	15838285
Pubmed	Upregulation of vascular ET(B) receptor gene expression after chronic ET(A) receptor blockade in prediabetic NOD mice.	EDNRA EDNRB	4.84e-06	2	77	2	15838254
Pubmed	Dual oxidase 1 and 2 expression in airway epithelium of smokers and patients with mild/moderate chronic obstructive pulmonary disease.	DUOX1 DUOX2	4.84e-06	2	77	2	18177232
Pubmed	Targeting endothelin receptors A and B attenuates the inflammatory response and improves locomotor function following spinal cord injury in mice.	EDNRA EDNRB	4.84e-06	2	77	2	24756152
Pubmed	Endothelin receptor blockade inhibits molecular effectors of Kaposi's sarcoma cell invasion and tumor growth in vivo.	EDNRA EDNRB	4.84e-06	2	77	2	12875994
Pubmed	Dual oxidases represent novel hydrogen peroxide sources supporting mucosal surface host defense.	DUOX1 DUOX2	4.84e-06	2	77	2	12824283
Pubmed	Associations of EDNRA and EDNRB Polymorphisms with Intracerebral Hemorrhage.	EDNRA EDNRB	4.84e-06	2	77	2	31150867
Pubmed	Congenital Hypothyroidism due to Oligogenic Mutations in Two Sudanese Families.	DUOX1 DUOX2	4.84e-06	2	77	2	30375286
Pubmed	Facial hyperalgesia due to direct action of endothelin-1 in the trigeminal ganglion of mice.	EDNRA EDNRB	4.84e-06	2	77	2	29570803
Pubmed	Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family.	DUOX1 DUOX2	4.84e-06	2	77	2	10806195
Pubmed	Tyrosine cross-linking of extracellular matrix is catalyzed by Duox, a multidomain oxidase/peroxidase with homology to the phagocyte oxidase subunit gp91phox.	DUOX1 DUOX2	4.84e-06	2	77	2	11514595
Pubmed	Roles of DUOX-mediated hydrogen peroxide in metabolism, host defense, and signaling.	DUOX1 DUOX2	4.84e-06	2	77	2	24161126
Pubmed	Role of ET(A) receptors in the vasoconstriction induced by endothelin-1 in subcutaneous small arteries of normotensive subjects and hypertensive patients.	EDNRA EDNRB	4.84e-06	2	77	2	11930911
Pubmed	Expression of reduced nicotinamide adenine dinucleotide phosphate oxidase (ThoX, LNOX, Duox) genes and proteins in human thyroid tissues.	DUOX1 DUOX2	4.84e-06	2	77	2	11443211
Pubmed	Purification of a novel flavoprotein involved in the thyroid NADPH oxidase. Cloning of the porcine and human cdnas.	DUOX1 DUOX2	4.84e-06	2	77	2	10601291
Pubmed	Combined knockout of collecting duct endothelin A and B receptors causes hypertension and sodium retention.	EDNRA EDNRB	4.84e-06	2	77	2	18784261
Pubmed	Selective in vivo antagonism of endothelin receptors in transforming growth factor-beta1 transgenic mice that mimic the vascular pathology of Alzheimer's disease.	EDNRA EDNRB	4.84e-06	2	77	2	20628431
Pubmed	Ischemic heart disease induces upregulation of endothelin receptor mRNA in human coronary arteries.	EDNRA EDNRB	4.84e-06	2	77	2	14729387
Pubmed	p70S6 kinase phosphorylates AMPK on serine 491 to mediate leptin's effect on food intake.	RPS6KB1 PRKAA2	4.84e-06	2	77	2	22727014
Pubmed	Agonist-promoted ubiquitination differentially regulates receptor trafficking of endothelin type A and type B receptors.	EDNRA EDNRB	4.84e-06	2	77	2	25381251
Pubmed	The extracellular A-loop of dual oxidases affects the specificity of reactive oxygen species release.	DUOX1 DUOX2	4.84e-06	2	77	2	25586178
Pubmed	Effects of endothelin-related gene polymorphisms and aerobic exercise habit on age-related arterial stiffening: a 10-yr longitudinal study.	EDNRA EDNRB	4.84e-06	2	77	2	29097630
Pubmed	The contractile effects of endothelins on isolated isthmic segment of human oviduct at the luteal phase of the menstrual cycle.	EDNRA EDNRB	4.84e-06	2	77	2	20401344
Pubmed	Differential regulation of dual NADPH oxidases/peroxidases, Duox1 and Duox2, by Th1 and Th2 cytokines in respiratory tract epithelium.	DUOX1 DUOX2	4.84e-06	2	77	2	16111680
Pubmed	Blood pressure regulation by ETA and ETB receptors in conscious, telemetry-instrumented mice and role of ETA in hypertension produced by selective ETB blockade.	EDNRA EDNRB	4.84e-06	2	77	2	16399858
Pubmed	Nox/Duox family of nicotinamide adenine dinucleotide (phosphate) oxidases.	DUOX1 DUOX2	4.84e-06	2	77	2	11753072
Pubmed	Silencing of DUOX NADPH oxidases by promoter hypermethylation in lung cancer.	DUOX1 DUOX2	4.84e-06	2	77	2	18281478
Pubmed	Structural and functional characterization of the two human ThOX/Duox genes and their 5'-flanking regions.	DUOX1 DUOX2	4.84e-06	2	77	2	15062544
Pubmed	Regulated hydrogen peroxide production by Duox in human airway epithelial cells.	DUOX1 DUOX2	4.84e-06	2	77	2	15677770
Pubmed	Role of endothelin-1 and its receptors, ETA and ETB, in the survival of human vascular endothelial cells.	EDNRA EDNRB	4.84e-06	2	77	2	28732172
Pubmed	Ovarian hormones modulate endothelin-1 receptor responses in young women.	EDNRA EDNRB	4.84e-06	2	77	2	29999581
Pubmed	Mucosal reactive oxygen species are required for antiviral response: role of Duox in influenza a virus infection.	DUOX1 DUOX2	4.84e-06	2	77	2	24128054
Pubmed	Cloning and chromosomal localization of a human endothelin ETA receptor.	EDNRA EDNRB	4.84e-06	2	77	2	1659806
Pubmed	Up-regulation of endothelin receptors induced by cigarette smoke--involvement of MAPK in vascular and airway hyper-reactivity.	EDNRA EDNRB	4.84e-06	2	77	2	21057729
Pubmed	ADP-ribosyl cyclase and ryanodine receptors mediate endothelin ETA and ETB receptor-induced renal vasoconstriction in vivo.	EDNRA EDNRB	1.45e-05	3	77	2	18524860
Pubmed	TNFα-induced airway smooth muscle cell proliferation depends on endothelin receptor signaling, GM-CSF and IL-6.	EDNRA EDNRB	1.45e-05	3	77	2	27422754
Pubmed	Overexpression of endothelin-1 and endothelin receptors in the pulmonary arteries of failed Fontan patients.	EDNRA EDNRB	1.45e-05	3	77	2	21356562
Pubmed	Endothelin-3 induces both human and opossum gallbladder contraction mediated mainly by endothelin-B receptor subtype in vitro.	EDNRA EDNRB	1.45e-05	3	77	2	11982704
Pubmed	Function and survival of dendritic cells depend on endothelin-1 and endothelin receptor autocrine loops.	EDNRA EDNRB	1.45e-05	3	77	2	15213100
Pubmed	C-terminus of ETA/ETB receptors regulate endothelin-1 signal transmission.	EDNRA EDNRB	1.45e-05	3	77	2	23436727
Pubmed	Altered role of smooth muscle endothelin receptors in coronary endothelin-1 and alpha1-adrenoceptor-mediated vasoconstriction in Type 2 diabetes.	EDNRA EDNRB	1.45e-05	3	77	2	17660396
Pubmed	New concepts in endothelin control of sodium balance.	EDNRA EDNRB	1.45e-05	3	77	2	21418087
Pubmed	Functional coupling of G proteins to endothelin receptors is ligand and receptor subtype specific.	EDNRA EDNRB	1.45e-05	3	77	2	10789830
Pubmed	NADPH oxidase DUOX1 and DUOX2 but not NOX4 are independent predictors in hepatocellular carcinoma after hepatectomy.	DUOX1 DUOX2	1.45e-05	3	77	2	21915726
Pubmed	Expression and cellular localisation of renal endothelin-1 and endothelin receptor subtypes in autosomal-dominant polycystic kidney disease.	EDNRA EDNRB	1.45e-05	3	77	2	12629276
Pubmed	Endothelin-1 promotes vascular smooth muscle cell migration across the artery wall: a mechanism contributing to vascular remodelling and intimal hyperplasia in giant-cell arteritis.	EDNRA EDNRB	1.45e-05	3	77	2	28606962
Pubmed	Endothelin-1 inhibits sodium reabsorption by ET(A) and ET(B) receptors in the mouse cortical collecting duct.	EDNRA EDNRB	1.45e-05	3	77	2	23698114
Pubmed	Endothelin axis polymorphisms in patients with scleroderma.	EDNRA EDNRB	1.45e-05	3	77	2	16947775
Pubmed	Complex expression changes of the placental endothelin system in early and late onset preeclampsia, fetal growth restriction and gestational diabetes.	EDNRA EDNRB	1.45e-05	3	77	2	22580289
Pubmed	Direct action of endothelin-1 on podocytes promotes diabetic glomerulosclerosis.	EDNRA EDNRB	1.45e-05	3	77	2	24722437
Pubmed	Endothelin ETB receptor heterodimerization: beyond the ETA receptor.	EDNRA EDNRB	1.45e-05	3	77	2	18756291
Pubmed	Expression and localization of endothelin-1 and its receptors in the spiral ganglion neurons of mouse.	EDNRA EDNRB	1.45e-05	3	77	2	19370413
Pubmed	Vascular derived endothelin receptor A controls endothelin-induced retinal ganglion cell death.	EDNRA EDNRB	1.45e-05	3	77	2	35429992
Pubmed	Endothelin-1 and endothelin receptor gene variants and their association with negative outcomes following aneurysmal subarachnoid hemorrhage.	EDNRA EDNRB	1.45e-05	3	77	2	22997346
Pubmed	Jab1 regulates levels of endothelin type A and B receptors by promoting ubiquitination and degradation.	EDNRA EDNRB	1.45e-05	3	77	2	20034471
Pubmed	Increased expression of endothelin-1 and endothelin receptor A in reflux esophagitis and Barrett's esophagus.	EDNRA EDNRB	1.45e-05	3	77	2	23384184
Pubmed	Transforming growth factor-β regulates endothelin-1 signaling in the newborn mouse lung during hypoxia exposure.	EDNRA EDNRB	1.45e-05	3	77	2	22287612
Pubmed	ETB receptor polymorphism is associated with airway obstruction.	EDNRA EDNRB	1.45e-05	3	77	2	17470272
Pubmed	Gene expression of endothelin receptors in replaced rheumatic mitral stenotic valves.	EDNRA EDNRB	1.45e-05	3	77	2	23515723
Pubmed	CD31, EDNRB and TSPAN7 are promising prognostic markers in clear-cell renal cell carcinoma revealed by genome-wide expression analyses of primary tumors and metastases.	TSPAN7 EDNRB	1.45e-05	3	77	2	22213152
Pubmed	NADPH oxidase-dependent acid production in airway epithelial cells.	DUOX1 DUOX2	1.45e-05	3	77	2	15210697
Pubmed	Expression of the Endothelin-axis in the different histologic subtypes of renal cell carcinoma: a tissue microarray analysis.	EDNRA EDNRB	1.45e-05	3	77	2	17203161
Pubmed	Activation of endothelin-1 receptor signaling pathways is associated with neointima formation, neoangiogenesis and irreversible pulmonary artery hypertension in patients with congenital heart disease.	EDNRA EDNRB	1.45e-05	3	77	2	21498912
Pubmed	Endothelin receptor type B counteracts tenascin-C-induced endothelin receptor type A-dependent focal adhesion and actin stress fiber disorganization.	EDNRA EDNRB	1.45e-05	3	77	2	17616673
Pubmed	Role of nicotinamide adenine dinucleotide phosphate oxidase in mediating vesicant-induced interleukin-6 secretion in human airway epithelial cells.	DUOX1 DUOX2	1.45e-05	3	77	2	24164541
Cytoband	11q12.1	OR5AK2 OR5AN1 OR5AK3P OR4D11 OR8U3	8.03e-06	161	77	5	11q12.1
Cytoband	15q15.3	DUOX1 SERINC4 DUOX2	1.02e-05	25	77	3	15q15.3
Cytoband	1q44	OR2T27 OR13G1 OR1C1 OR2L13	3.69e-05	110	77	4	1q44
Cytoband	Ensembl 112 genes in cytogenetic band chr1q44	OR2T27 OR13G1 OR1C1 OR2L13	6.66e-05	128	77	4	chr1q44
Cytoband	Ensembl 112 genes in cytogenetic band chr11q12	OR5AK2 OR5AN1 OR5AK3P OR4D11 OR8U3	2.95e-04	345	77	5	chr11q12
Cytoband	7q22.1	MUC17 PMPCB MYH16	9.30e-04	113	77	3	7q22.1
Cytoband	21q22.3	DIP2A KRTAP10-7 KRTAP10-6	1.33e-03	128	77	3	21q22.3
Cytoband	Xp11.4	GPR34 TSPAN7	1.50e-03	34	77	2	Xp11.4
Cytoband	11p15.4	OR51Q1 OR51I2 OR56A3	4.70e-03	200	77	3	11p15.4
Cytoband	Ensembl 112 genes in cytogenetic band chr7q22	MUC17 PMPCB MYH16	6.04e-03	219	77	3	chr7q22
GeneFamily	Endothelin receptors	EDNRA EDNRB	9.09e-06	2	55	2	225
GeneFamily	Olfactory receptors, family 5	OR5AC2 OR5AK2 OR5AN1 OR5AK3P OR8U3	2.27e-05	112	55	5	152
ToppCell	Monocytes-NUPR1+_Monocytes\|Monocytes / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	TANC2 PMPCB GPR34 DHRS7 KPNA6 SNRNP200	1.02e-06	197	75	6	8a058c9d9285acd7cf2fb8e34f7602a86b5d6c89
ToppCell	PBMC-Severe-Lymphocyte-T/NK-NK_cell-NK\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	DIP2A COPZ2 DHRS7 TKTL1 TTC38	2.01e-05	196	75	5	d3bd8fab010e76024d7e06aba0ea5df3394f411f
ToppCell	PBMC-Severe-Lymphocyte-T/NK-NK_cell-NK-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	DIP2A COPZ2 DHRS7 TKTL1 TTC38	2.01e-05	196	75	5	77da6b1bcab45d376eb0368f540e0ed24ce98b42
ToppCell	severe-NK\|severe / disease stage, cell group and cell class	DIP2A RASA2 DHRS7 TKTL1 TTC38	2.11e-05	198	75	5	cb505077dc5bdf3fdd513bb9032e32bb9644c004
ToppCell	3'-Child04-06-SmallIntestine-Epithelial\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MUC17 UGT2B17 REG1A CUBN CES2	2.16e-05	199	75	5	ab71b312635a2b2c98d71b60a299f44bc80a3587
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-T/NK-NK\|COVID-19_Severe / Disease, condition lineage and cell class	DIP2A COPZ2 DHRS7 TKTL1 TTC38	2.21e-05	200	75	5	2580b7b83ba707718fe23ffca986e7a55ea85bce
Drug	Vidarabine [5536-17-4]; Up 200; 15uM; HL60; HT_HG-U133A	TANC2 IL1RAPL2 MTHFR LAMA4 TKTL1 TTC38 VPS13B EDNRA	2.99e-07	196	76	8	2706_UP
Drug	Bosentan	EDNRA EDNRB	1.10e-05	2	76	2	DB00559
Drug	TAK 044	EDNRA EDNRB	1.10e-05	2	76	2	ctd:C088196
Drug	6-bromo-2,3-dihydrobenzofuran	EDNRA EDNRB	1.10e-05	2	76	2	CID011252616
Drug	Sitaxentan	EDNRA EDNRB	1.10e-05	2	76	2	DB06268
Drug	A 182086	EDNRA EDNRB	1.10e-05	2	76	2	ctd:C467893
Drug	1H-Indene-2-carboxylic acid, 1-(1,3-benzodioxol-5-yl)-3-(2- (carboxymethoxy)-4-methoxyphenyl)-2,3-dihydro-5-propoxy-, (1S,2R,3S)-	EDNRA EDNRB	1.10e-05	2	76	2	ctd:C087551
Drug	IRL 1620	EDNRA EDNRB	1.10e-05	2	76	2	ctd:C074308
Drug	PD 156252	EDNRA EDNRB	1.10e-05	2	76	2	ctd:C106950
Drug	enrasentan	EDNRA EDNRB	1.10e-05	2	76	2	ctd:C098288
Drug	PD 145065	EDNRA EDNRB	1.10e-05	2	76	2	ctd:C082887
Drug	LU 224332	EDNRA EDNRB	1.10e-05	2	76	2	ctd:C113044
Drug	L-671,776	EDNRA EDNRB	1.10e-05	2	76	2	CID000122853
Drug	tezosentan	EDNRA EDNRB	1.10e-05	2	76	2	ctd:C120582
Drug	spirodihydrobenzofuranlactam VI	EDNRA EDNRB	1.10e-05	2	76	2	CID000469820
Drug	J 104132	EDNRA EDNRB	1.10e-05	2	76	2	ctd:C119319
Drug	M 603	EDNRA EDNRB OPRM1	1.58e-05	15	76	3	CID000162977
Drug	AC1L1GI5	DUOX1 DUOX2 EDNRA CES2	1.83e-05	47	76	4	CID000003693
Drug	potassium acetate	PAM REG1A DHX9	2.35e-05	17	76	3	CID000517044
Drug	AC1L3U2Y	GCK EDNRA EDNRB	2.81e-05	18	76	3	CID000122149
Drug	WS009A	EDNRA EDNRB	3.29e-05	3	76	2	CID000131948
Drug	Pd164333	EDNRA EDNRB	3.29e-05	3	76	2	CID005311351
Drug	2-nitrobenzoyl chloride	EDNRA EDNRB	3.29e-05	3	76	2	CID000011875
Drug	E106E	EDNRA EDNRB	3.29e-05	3	76	2	CID000026761
Drug	pyrazolinone	EDNRA EDNRB	3.29e-05	3	76	2	CID000351317
Drug	2-ethylacetanilide	EDNRA EDNRB	3.29e-05	3	76	2	CID000036332
Drug	ZD 2574	EDNRA EDNRB	3.29e-05	3	76	2	ctd:C415840
Drug	myriceric acid C	EDNRA EDNRB	3.29e-05	3	76	2	CID005274625
Drug	NSC 90	EDNRA EDNRB	3.29e-05	3	76	2	CID000073811
Drug	Hyoscyamine (L) [101-31-5]; Down 200; 13.8uM; MCF7; HT_HG-U133A	PER1 CACNA1H MLXIP ARHGEF2 TTC38 EDNRA	4.45e-05	192	76	6	2271_DN
Drug	BQ-788	GCK EDNRA EDNRB	4.55e-05	21	76	3	CID003081333
Drug	yohimbine; Down 200; 22.9uM; MCF7; HT_HG-U133A_EA	ZNF384 KPNA6 WDR1 SEC22A VPS13B CES2	4.86e-05	195	76	6	1119_DN
Drug	Picotamide monohydrate [80530-63-8]; Up 200; 10.2uM; MCF7; HT_HG-U133A	COPZ2 MTHFR PRKAA2 CACNA1H MLXIP USP9Y	5.00e-05	196	76	6	2233_UP
Drug	Ritodrine hydrochloride [23239-51-2]; Up 200; 12.4uM; MCF7; HT_HG-U133A	PRKAA2 PER1 LAMA4 USP9Y EDNRA EDNRB	5.29e-05	198	76	6	5680_UP
Drug	0179445-0000 [211246-22-9]; Up 200; 1uM; PC3; HT_HG-U133A	KIFAP3 DUOX1 ABCA1 COPZ2 ARHGEF2 EDNRA	5.29e-05	198	76	6	3736_UP
Drug	4-phenoxybutyric acid	EDNRA EDNRB	6.57e-05	4	76	2	CID000022741
Drug	sarafotoxins s6	EDNRA EDNRB	6.57e-05	4	76	2	ctd:C057354
Drug	indane-2-carboxylic acid	EDNRA EDNRB	6.57e-05	4	76	2	CID000575777
Drug	Meperidine	CES2 OPRM1	6.57e-05	4	76	2	ctd:D008614
Drug	Sch 39370	PER1 EDNRA EDNRB	9.87e-05	27	76	3	CID000121872
Drug	pd 151242	EDNRA EDNRB	1.09e-04	5	76	2	CID000132991
Drug	1,5-dihydroxyisoquinoline	EDNRA EDNRB	1.09e-04	5	76	2	ctd:C095653
Drug	Et-(16-21)	EDNRA EDNRB	1.09e-04	5	76	2	CID000129432
Drug	L015040	EDNRA EDNRB	1.09e-04	5	76	2	CID004574540
Drug	SM-20550	PAM EDNRA	1.09e-04	5	76	2	CID006918358
Drug	butynediol	EDNRA EDNRB	1.09e-04	5	76	2	CID000008066
Drug	2-phenylethenesulfonamide	EDNRA EDNRB	1.09e-04	5	76	2	CID000257501
Drug	Be 18257a	EDNRA EDNRB	1.09e-04	5	76	2	CID000197302
Drug	SB 234551	EDNRA EDNRB	1.09e-04	5	76	2	CID005311425
Drug	CGS 27830	EDNRA EDNRB	1.64e-04	6	76	2	CID000190809
Drug	Bq 153	EDNRA EDNRB	1.64e-04	6	76	2	CID000196897
Drug	A-192621	EDNRA EDNRB	1.64e-04	6	76	2	CID005310991
Drug	Bq 928	EDNRA EDNRB	1.64e-04	6	76	2	CID000133071
Drug	R)-3-pyrrolidinecarboxylic acid	EDNRA EDNRB	1.64e-04	6	76	2	CID001501969
Drug	19-oxo-11-deoxycorticosterone acetate	EDNRA EDNRB	2.28e-04	7	76	2	ctd:C040168
Drug	Dextropropoxyphene	CES2 OPRM1	2.28e-04	7	76	2	ctd:D011431
Drug	2,1,3-benzothiadiazole	EDNRA EDNRB	2.28e-04	7	76	2	CID000067502
Drug	dibenzocycloheptatriene	EDNRA EDNRB	2.28e-04	7	76	2	CID000067492
Drug	hexametaphosphate	PER1 GCK	2.28e-04	7	76	2	CID000024969
Drug	Be 18257b	EDNRA EDNRB	2.28e-04	7	76	2	CID000197303
Drug	losigamone	PER1 CACNA1H	2.28e-04	7	76	2	CID000060572
Drug	CI-907	EDNRA EDNRB CES2	2.56e-04	37	76	3	CID000005525
Disease	phenylketonuria (implicated_via_orthology)	DUOX1 DUOX2	3.04e-05	4	67	2	DOID:9281 (implicated_via_orthology)
Disease	unipolar depression, smoking behaviour measurement	OR5AK2 OR5AK3P	3.04e-05	4	67	2	EFO_0003761, EFO_0005671
Disease	Graft-vs-Host Disease	MTHFR UGT2B17	7.57e-05	6	67	2	C0018133
Disease	coronary artery disease (is_implicated_in)	ABCA1 MTHFR GCK CUBN	8.08e-05	100	67	4	DOID:3393 (is_implicated_in)
Disease	Depression, Postpartum	MTHFR OPRM1	1.06e-04	7	67	2	C0221074
Disease	migraine (is_implicated_in)	MTHFR EDNRA	1.81e-04	9	67	2	DOID:6364 (is_implicated_in)
Disease	primary bacterial infectious disease (implicated_via_orthology)	DUOX1 DUOX2	1.81e-04	9	67	2	DOID:0050338 (implicated_via_orthology)
Disease	Acute Cerebrovascular Accidents	MTHFR PRKAA2 EDNRA	2.55e-04	54	67	3	C0751956
Disease	Cerebrovascular accident	MTHFR PRKAA2 EDNRA	3.85e-04	62	67	3	C0038454
Disease	hypothyroidism (implicated_via_orthology)	DUOX1 DUOX2	3.90e-04	13	67	2	DOID:1459 (implicated_via_orthology)
Disease	trimethylamine-N-oxide measurement	TAS1R2 CUBN	4.54e-04	14	67	2	EFO_0010541
Disease	congenital hypothyroidism (implicated_via_orthology)	DUOX1 DUOX2	4.54e-04	14	67	2	DOID:0050328 (implicated_via_orthology)
Disease	type 2 diabetes mellitus (is_implicated_in)	ABCA1 MTHFR PRKAA2 GCK	6.28e-04	171	67	4	DOID:9352 (is_implicated_in)
Disease	Malignant neoplasm of breast	IL1RAPL2 MTHFR PRKAA2 PER1 NUP214 CUBN VPS13B EDNRA EDNRB	6.96e-04	1074	67	9	C0006142
Disease	portal hypertension (implicated_via_orthology)	EDNRA EDNRB	8.47e-04	19	67	2	DOID:10762 (implicated_via_orthology)
Disease	Alopecia	MTHFR EDNRA	8.47e-04	19	67	2	C0002170
Disease	Drug toxicity	MTHFR CACNA1H CES2	9.35e-04	84	67	3	C0013221
Disease	Adverse reaction to drug	MTHFR CACNA1H CES2	9.35e-04	84	67	3	C0041755
Disease	systemic mastocytosis	ABCA1 OR51Q1	1.47e-03	25	67	2	MONDO_0016586
Disease	Seizures	TANC2 MTHFR PAM OPRM1	1.54e-03	218	67	4	C0036572
Disease	Diabetes Mellitus, Non-Insulin-Dependent	PAM GCK EDNRA EDNRB	1.62e-03	221	67	4	C0011860
Disease	type 2 diabetes mellitus (implicated_via_orthology)	RPS6KB1 GCK EDNRB	1.78e-03	105	67	3	DOID:9352 (implicated_via_orthology)
Disease	glucose metabolism disease (implicated_via_orthology)	RPS6KB1 GCK	1.85e-03	28	67	2	DOID:4194 (implicated_via_orthology)
Disease	Thrombocytopenia	MTHFR WDR1	1.98e-03	29	67	2	C0040034

Protein segments in the cluster

Peptide	Gene	Start	Entry
MDTYSKMGEVFTDLC	CAMLG	261	P49069
SSFLYTVDSMLLDME	HTR3E	181	A5X5Y0
DSSSSVLEFMSMKSY	BRD9	481	Q9H8M2
TMDFFEMCASLITTL	PRKAA2	536	P54646
LFTTISVSGMTMCYA	ARHGEF2	41	Q92974
SYENELMLMSVLTCL	COPZ2	116	Q9P299
SSFNSCLDPVMYFLM	GPR34	316	Q9UPC5
LTTSVSMMLFDTFLY	ABCA1	821	O95477
SDTYFCMSMRIPVDE	PAM	71	P19021
TAIFYTLMTCEMLNR	EDNRA	271	P25101
LAITAFFYTLMTCEM	EDNRB	286	P24530
MSQRSLCMDTSLDVY	DHRS7	141	Q9Y394
SSTMTCMKDTYLVHL	CHML	496	P26374
SMSCPTVMCDIFYSL	RASA2	471	Q15283
TVMCDIFYSLRQMAT	RASA2	476	Q15283
AMVNDTVATMISCYY	GCK	201	P35557
ASISFMFSYILLTMC	DUOX1	1091	Q9NRD9
STSAMVYIFIQMSCE	DEPDC5	166	O75140
YMVCESSTVADMLHV	PMPCB	366	O75439
DIFSLSVMAFDCYMA	OR4D11	111	Q8NGI4
AMFDSLLMDSYVSST	KPNA6	61	O60684
ETSSMMIASTAVNYC	MTHFR	106	P42898
YNMFTSIFTLCTMSV	OPRM1	151	P35372
TMLTSENTISYAGCM	OR13G1	81	Q8NGZ3
LSTLRCYEDTMLAAM	KCTD7	66	Q96MP8
SFMFSYILLTMCRNL	DUOX2	1091	Q9NRD8
EPCSMDMSTYTLEEL	PER1	191	O15534
YFLSMLSFSDVAISM	OR51I2	61	Q9H344
FMESSVLLAMSVDCY	OR51Q1	111	Q8NH59
NMTFPSDSMSEDCLY	CES2	111	O00748
MEDTACFYLAEISMA	RPS6KB1	191	P23443
TLSACMMSSEYGSII	NUP214	106	P35658
TSFMMALCLSSIYED	IL12A	116	P29459
DTSAYETAMYVCCIM	OR2T27	191	Q8NH04
RSYEDQLSMMSDHLC	PPP1R21	736	Q6ZMI0
SESCLMTAMAYDRYA	OR5AN1	111	Q8NGI8
AFMTAECLLLASMAY	OR8U9	106	P0C7N5
TFATSDCYLLAIMAM	OR5AK3P	106	Q8NH89
FASSATTECFLLVMM	OR5AC2	106	Q9NZP5
TFATSDCYLLAMMAV	OR5AK2	106	Q8NH90
MLMSEFSDTLFSTLS	MLXIP	276	Q9HAP2
DSCIMAYDGLSSTMS	CUBN	1561	O60494
MAASTMSVCSSDLSY	KRTAP10-6	1	P60371
MAASTMSVCSSDLSY	KRTAP10-7	1	P60409
ARVTFCSYSVMEMCT	DIP2A	1241	Q14689
TMDNVATFCTLLMLF	CACNA1H	911	O95180
NFISSLGVSYMMLCT	SEC22A	61	Q96IW7
LMSATIDTSMFCEYF	DHX9	541	Q08211
SMDDRFKSMFAYTDC	KIFAP3	411	Q92845
MKLSCSSTYDVEMTV	OR8A1	201	Q8NGG7
SFVNMDSLLLCVMAY	OR1C1	106	Q15619
SYFMLISCLMFLSQS	REG1A	6	P05451
SMDDLKAFTSLSLYM	LAMA4	851	Q16363
MACSEGLLLTSMAYD	OR2L13	106	Q8N349
MYLSCSTNPEMTSIE	MUC17	81	Q685J3
STYCMKVSMSLTVAE	IL1RAPL2	121	Q9NP60
MMEVESSYSDFISCD	PKIG	1	Q9Y2B9
MDSCLYRVDENMTAS	TANC2	221	Q9HCD6
FLAMESCTFMVMAYD	OR56A3	111	Q8NH54
SCSMDDTVRYTSLML	WDR1	381	O75083
TTVMTCAYLAGLSML	MRGPRX2	106	Q96LB1
TFMITECFLLASMAY	OR8U3	106	Q8NH85
SIMDEFQEYTMLCLL	CHURC1	76	Q8WUH1
CLVCEMSSLFHAMYS	USP51	406	Q70EK9
RMCSLTFYSKSEMQI	ZNF384	231	Q8TF68
MSYLTAMGADYLSCD	TJP2	901	Q9UDY2
DFFISLLESYMSMCE	THOC2	226	Q8NI27
ASMTYLVSMESCAES	STOX1	216	Q6ZVD7
AMLSASIMYACVLFA	SERINC4	341	A6NH21
DLISHSEMFSDSYMS	nan	11	Q56UQ5
TEMYYMGTAITTCEA	USP9Y	1526	O00507
MTFYFTSSVSLCTFM	TAS1R2	766	Q8TE23
DSSQKECRMYMTESF	MYH16	631	Q9H6N6
MMILYCTLLASAQSE	SNRNP200	326	O75643
NDAMLDVVDSCSMLY	TTC38	286	Q5R3I4
ITASRISLMTYSCMA	VPS13B	1841	Q7Z7G8
CYDLVTSFMETNMGI	TSPAN7	201	P41732
SSSSEIMSVLFFYIM	TKTL1	51	P51854
MSVFLLMQLSCYFSS	UGT2B17	6	O75795