Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor	GLUD1 GLUD2	2.06e-04	2	287	2	GO:0016639
GeneOntologyMolecularFunction	glutamate dehydrogenase [NAD(P)+] activity	GLUD1 GLUD2	2.06e-04	2	287	2	GO:0004353
GeneOntologyMolecularFunction	glutamate dehydrogenase (NAD+) activity	GLUD1 GLUD2	2.06e-04	2	287	2	GO:0004352
GeneOntologyMolecularFunction	glutamate dehydrogenase (NADP+) activity	GLUD1 GLUD2	2.06e-04	2	287	2	GO:0004354
MousePheno	abnormal seminal vesicle epithelium morphology	SERPINE2 HERC6 GDF7	1.52e-05	4	220	3	MP:0013899
Domain	NUT	NUTM2A NUTM2G NUTM1 NUTM2B NUTM2F	7.71e-10	5	283	5	IPR024310
Domain	NUT_N	NUTM2A NUTM2G NUTM1 NUTM2B NUTM2F	7.71e-10	5	283	5	IPR024309
Domain	NUT	NUTM2A NUTM2G NUTM1 NUTM2B NUTM2F	7.71e-10	5	283	5	PF12881
Domain	HEAT_REPEAT	DOHH CAND2 NCAPG2 BRAT1 RANBP6 COPG2 HEATR5A PPP2R1B MROH2B HTT	9.69e-08	70	283	10	PS50077
Domain	ARM-type_fold	DOHH CAND2 LRRK2 NCBP1 NCAPG2 RRP12 AP1G2 ZER1 BRAT1 RNPEPL1 UBR4 RANBP6 COPG2 HEATR5A PPP2R1B PPP2R5D MROH2B HTT	4.57e-06	339	283	18	IPR016024
Domain	-	DOHH CAND2 LRRK2 NCAPG2 RRP12 AP1G2 ZER1 BRAT1 RANBP6 COPG2 HEATR5A PPP2R1B MROH2B HTT	7.81e-06	222	283	14	1.25.10.10
Domain	ARM-like	DOHH CAND2 LRRK2 NCAPG2 RRP12 AP1G2 ZER1 BRAT1 DOCK10 RANBP6 COPG2 HEATR5A PPP2R1B MROH2B HTT	1.69e-05	270	283	15	IPR011989
Domain	HEAT	DOHH CAND2 NCAPG2 BRAT1 RANBP6 PPP2R1B HTT	2.64e-05	58	283	7	IPR000357
Domain	HEAT	CAND2 NCAPG2 BRAT1 RANBP6 PPP2R1B HTT	8.25e-05	48	283	6	PF02985
Domain	ELFV_dehydrog_N	GLUD1 GLUD2	2.29e-04	2	283	2	PF02812
Domain	COR	LRRK2 LRRK1	2.29e-04	2	283	2	IPR032171
Domain	ELFV_dehydrog	GLUD1 GLUD2	2.29e-04	2	283	2	PF00208
Domain	NAD_bind_Glu_DH	GLUD1 GLUD2	2.29e-04	2	283	2	IPR033922
Domain	DUF4795	QRICH2 C16orf96	2.29e-04	2	283	2	IPR032013
Domain	ELFV_dehydrog	GLUD1 GLUD2	2.29e-04	2	283	2	SM00839
Domain	Glu/Leu/Phe/Val_DH_C	GLUD1 GLUD2	2.29e-04	2	283	2	IPR006096
Domain	Glu/Leu/Phe/Val_DH_dimer_dom	GLUD1 GLUD2	2.29e-04	2	283	2	IPR006097
Domain	Glu/Leu/Phe/Val_DH	GLUD1 GLUD2	2.29e-04	2	283	2	IPR006095
Domain	GLFV_DEHYDROGENASE	GLUD1 GLUD2	2.29e-04	2	283	2	PS00074
Domain	COR	LRRK2 LRRK1	2.29e-04	2	283	2	PF16095
Domain	Cbl-bd_cap	COPG2 MTR	2.29e-04	2	283	2	IPR003759
Domain	DUF4795	QRICH2 C16orf96	2.29e-04	2	283	2	PF16043
Domain	Glu/Leu/Phe/Val_DH_AS	GLUD1 GLUD2	2.29e-04	2	283	2	IPR033524
Domain	Orgcat_transp/SVOP	SLC22A7 SLC22A4 SLC22A5	2.70e-04	9	283	3	IPR004749
Domain	Quino_amine_DH_bsu	LRRK2 NID2 LRRK1 TEP1	3.04e-04	22	283	4	IPR011044
Domain	DUF4599	SPATA31C1 SPATA31D4 SPATA31D3	6.84e-04	12	283	3	PF15371
Domain	DUF4599	SPATA31C1 SPATA31D4 SPATA31D3	6.84e-04	12	283	3	IPR027970
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	VWA5B2 SREBF1 CARD10 KLF4 FHIP1B TTC3 ZZEF1 BIRC6 AHDC1 TNRC18 WIZ RRP12 AP1G2 ZER1 SIPA1L2 BRAT1 DPH2 RANBP10 FRAS1 SH3RF1 SZT2 RNPEPL1 UBR4 HIP1R PAPLN LRRK1 TEP1 TBC1D17 INTS5 NADSYN1 CELSR3 TRIM28 BTBD7 ANKRD34A DISP2 DOT1L CABIN1 SPEN DHX34 HTT	1.10e-14	1105	294	40	35748872
Pubmed	Isolation of zebrafish gdf7 and comparative genetic mapping of genes belonging to the growth/differentiation factor 5, 6, 7 subgroup of the TGF-beta superfamily.	GDF5 GDF6 GDF7	5.98e-07	3	294	3	10022976
Pubmed	Cutting edge: Suppressor of cytokine signaling 3 inhibits activation of NFATp.	NFATC2 RCAN1 PPP3CB	2.38e-06	4	294	3	11970967
Pubmed	Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.	NHLRC1 GDF5 CARD10 ZP3 ARID5A FANCG FAM120C RNASEH2C ZNF574 LETMD1 PIM2 NTN3 TSPAN32 TEP1 GSC TBC1D17 CCNT1 PPP2R1B PPP2R5D GTF2H4 DHX34 ZNF646	2.91e-06	832	294	22	36724073
Pubmed	MDM2 interaction with nuclear corepressor KAP1 contributes to p53 inactivation.	CDKN2A TRIM28 TP53	5.90e-06	5	294	3	16107876
Pubmed	Differential expression of the actin-binding proteins, alpha-actinin-2 and -3, in different species: implications for the evolution of functional redundancy.	MAG FZD9 LIPE MTR	6.35e-06	15	294	4	11440986
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	CDKN2A MTHFD2 FASTKD5 ZZEF1 TUBGCP5 WIZ FAM120C SCML1 SIPA1L2 WDR13 ZNF574 NID2 HDAC6 P3H3 C16orf96 SIPA1 TEP1 DICER1 CCNT1 ARHGEF33 TRIM28 MTR DHX34 TP53 ZNF646	1.10e-05	1116	294	25	31753913
Pubmed	Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells.	CDKN2A DICER1 TP53	1.17e-05	6	294	3	18591425
Pubmed	AIRE recruits P-TEFb for transcriptional elongation of target genes in medullary thymic epithelial cells.	AIRE CCNT1 CCNT2	1.17e-05	6	294	3	17938200
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	CDKN2A CAND2 MTHFD2 DISC1 COPB2 TUBGCP5 RRP12 GLUD1 GLUD2 SIPA1L2 BRAT1 HDAC6 SZT2 HIP1R RANBP6 EXOC5 MTR	1.89e-05	606	294	17	36538041
Pubmed	Multiple joint and skeletal patterning defects caused by single and double mutations in the mouse Gdf6 and Gdf5 genes.	GDF5 GDF6 GDF7	2.04e-05	7	294	3	12606286
Pubmed	Limb alterations in brachypodism mice due to mutations in a new member of the TGF beta-superfamily.	GDF5 GDF6 GDF7	2.04e-05	7	294	3	8145850
Pubmed	Bapx1 regulates patterning in the middle ear: altered regulatory role in the transition from the proximal jaw during vertebrate evolution.	GDF5 GDF6 GSC	2.04e-05	7	294	3	14973294
Pubmed	Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	FHIP1B GREB1L DLC1 INTS5 UNK DISP2 SSH2	2.67e-05	102	294	7	11214970
Pubmed	Generation and annotation of the DNA sequences of human chromosomes 2 and 4.	MTHFD2 INPP4A MAP3K20 RFTN2 GCKR FBXO41 RNPEPL1 GRK4 DOCK10 PPBP CCNT2 ARHGEF33 NHEJ1 HTT	2.81e-05	442	294	14	15815621
Pubmed	Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	JCAD RANBP10 FRAS1 STIM2 SH3RF1 ZSWIM5 BTBD7	2.85e-05	103	294	7	10819331
Pubmed	E3 ubiquitin ligase NEURL3 promotes innate antiviral response through catalyzing K63-linked ubiquitination of IRF7.	CDKN2A NFATC2 TRIM28 TP53	3.25e-05	22	294	4	35792897
Pubmed	TFIID component TAF7 functionally interacts with both TFIIH and P-TEFb.	CCNT1 CCNT2 GTF2H4	4.84e-05	9	294	3	18391197
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CAMTA2 FHIP1B NEDD4 RRP12 SIPA1L2 FRAS1 ZSWIM5 FRMPD1 DOCK10 HEATR5A BTBD7 DISP2 SPEN	4.98e-05	407	294	13	12693553
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CAND2 ZZEF1 ATG4B MED12L FBXO41 SZT2 HIP1R LRRK1 SHOC2 DICER1 INTS5 CELSR3 UNK DHX34 ZNF646	5.19e-05	529	294	15	14621295
Pubmed	Deregulated expression of p16INK4a and p53 pathway members in benign and malignant myoepithelial tumours of the salivary glands.	CDKN2A TP53	7.12e-05	2	294	2	19076682
Pubmed	Genome-wide analysis of p53-regulated transcription in Myc-driven lymphomas.	CDKN2A TP53	7.12e-05	2	294	2	28092679
Pubmed	Haplotype in the IBD5 region is associated with refractory Crohn's disease in Slovenian patients and modulates expression of the SLC22A5 gene.	SLC22A4 SLC22A5	7.12e-05	2	294	2	21695374
Pubmed	Is p16(INK4a) protein expression in oral ST lesions a reliable precancerous marker?	CDKN2A TP53	7.12e-05	2	294	2	18606525
Pubmed	Mutant p53-R273H mediates cancer cell survival and anoikis resistance through AKT-dependent suppression of BCL2-modifying factor (BMF).	BMF TP53	7.12e-05	2	294	2	26181206
Pubmed	Gain of function in the mouse model of a recurrent mutation p53N236S promotes the formation of double minute chromosomes and the oncogenic potential of p19ARF.	CDKN2A TP53	7.12e-05	2	294	2	28949402
Pubmed	Glutamate dehydrogenase is essential to sustain neuronal oxidative energy metabolism during stimulation.	GLUD1 GLUD2	7.12e-05	2	294	2	28621566
Pubmed	Genetic Alterations in the INK4a/ARF Locus: Effects on Melanoma Development and Progression.	CDKN2A TP53	7.12e-05	2	294	2	33076392
Pubmed	GluD1 knockout mice with a pure C57BL/6N background show impaired fear memory, social interaction, and enhanced depressive-like behavior.	GLUD1 GLUD2	7.12e-05	2	294	2	32078638
Pubmed	ARF and p53 coordinate tumor suppression of an oncogenic IFN-β-STAT1-ISG15 signaling axis.	CDKN2A TP53	7.12e-05	2	294	2	24726362
Pubmed	Real-time in vivo imaging of p16Ink4a reveals cross talk with p53.	CDKN2A TP53	7.12e-05	2	294	2	19667129
Pubmed	Motor Impairments and Dopaminergic Defects Caused by Loss of Leucine-Rich Repeat Kinase Function in Mice.	LRRK2 LRRK1	7.12e-05	2	294	2	35534227
Pubmed	Silencing of Dicer1 temporally separates pro- and anti-apoptotic signaling and confers susceptibility to chemotherapy in p53 mutated cells.	DICER1 TP53	7.12e-05	2	294	2	24846461
Pubmed	Substrate discrimination by ergothioneine transporter SLC22A4 and carnitine transporter SLC22A5: gain-of-function by interchange of selected amino acids.	SLC22A4 SLC22A5	7.12e-05	2	294	2	19814996
Pubmed	Atg4b-dependent autophagic flux alleviates Huntington's disease progression.	ATG4B HTT	7.12e-05	2	294	2	23861892
Pubmed	p53-Dependent and p53-independent activation of autophagy by ARF.	CDKN2A TP53	7.12e-05	2	294	2	18199527
Pubmed	Identification of the molecular dysfunction caused by glutamate dehydrogenase S445L mutation responsible for hyperinsulinism/hyperammonemia.	GLUD1 GLUD2	7.12e-05	2	294	2	28911206
Pubmed	Calmodulin suppresses synaptotagmin-2 transcription in cortical neurons.	SYTL2 CAMK1G	7.12e-05	2	294	2	20729199
Pubmed	Involvement of p53 and p16 tumor suppressor genes in recessive dystrophic epidermolysis bullosa-associated squamous cell carcinoma.	CDKN2A TP53	7.12e-05	2	294	2	15373786
Pubmed	Examining the contribution of smoking and HPV towards the etiology of oral cavity squamous cell carcinoma using high-throughput sequencing: A prospective observational study.	CDKN2A TP53	7.12e-05	2	294	2	30308005
Pubmed	Erlotinib resistance in mouse models of epidermal growth factor receptor-induced lung adenocarcinoma.	CDKN2A TP53	7.12e-05	2	294	2	20007486
Pubmed	Molecular basis of human glutamate dehydrogenase regulation under changing energy demands.	GLUD1 GLUD2	7.12e-05	2	294	2	15578726
Pubmed	Induction of KLF4 in basal keratinocytes blocks the proliferation-differentiation switch and initiates squamous epithelial dysplasia.	KLF4 TP53	7.12e-05	2	294	2	15674344
Pubmed	A high-throughput in vitro drug screen in a genetically engineered mouse model of diffuse intrinsic pontine glioma identifies BMS-754807 as a promising therapeutic agent.	CDKN2A TP53	7.12e-05	2	294	2	25748921
Pubmed	Krüppel-like factor 4 (KLF4) facilitates lipid production in immortalized human sebocytes via regulating the expression of SREBP1.	SREBF1 KLF4	7.12e-05	2	294	2	37229823
Pubmed	Induction of excitatory and inhibitory presynaptic differentiation by GluD1.	GLUD1 GLUD2	7.12e-05	2	294	2	22138648
Pubmed	Basaloid squamous cell carcinoma of the esophagus: assessment for high-risk human papillomavirus and related molecular markers.	CDKN2A TP53	7.12e-05	2	294	2	19738459
Pubmed	Transport of ipratropium, an anti-chronic obstructive pulmonary disease drug, is mediated by organic cation/carnitine transporters in human bronchial epithelial cells: implications for carrier-mediated pulmonary absorption.	SLC22A4 SLC22A5	7.12e-05	2	294	2	20020740
Pubmed	High-dose cytarabine does not overcome the adverse prognostic value of CDKN2A and TP53 deletions in mantle cell lymphoma.	CDKN2A TP53	7.12e-05	2	294	2	26022239
Pubmed	Surface plasmon resonance imaging protein arrays for analysis of triple protein interactions of HPV, E6, E6AP, and p53.	UBE3A TP53	7.12e-05	2	294	2	16493710
Pubmed	p53-independent apoptosis is induced by the p19ARF tumor suppressor.	CDKN2A TP53	7.12e-05	2	294	2	12099684
Pubmed	Human tumor suppressor ARF impedes S-phase progression independent of p53.	CDKN2A TP53	7.12e-05	2	294	2	11861400
Pubmed	P16 and p53 play distinct roles in different subtypes of breast cancer.	CDKN2A TP53	7.12e-05	2	294	2	24146864
Pubmed	Inhibiting USP16 rescues stem cell aging and memory in an Alzheimer's model.	CDKN2A USP16	7.12e-05	2	294	2	35311644
Pubmed	Cooperativity of p19ARF, Mdm2, and p53 in murine tumorigenesis.	CDKN2A TP53	7.12e-05	2	294	2	14586409
Pubmed	Characterization of the complex of the lysosomal membrane transporter MFSD1 and its accessory subunit GLMP.	GLMP MFSD1	7.12e-05	2	294	2	32959924
Pubmed	Arf and p53 act as guardians of a quiescent cellular state by protecting against immortalization of cells with stable genomes.	CDKN2A TP53	7.12e-05	2	294	2	23376716
Pubmed	Loss of p19(Arf) facilitates the angiogenic switch and tumor initiation in a multi-stage cancer model via p53-dependent and independent mechanisms.	CDKN2A TP53	7.12e-05	2	294	2	20805995
Pubmed	Identification of candidate cancer-causing genes in mouse brain tumors by retroviral tagging.	CDKN2A TP53	7.12e-05	2	294	2	15273287
Pubmed	Comparative analysis of P16 and P53 expression in uterine malignant mixed mullerian tumors.	CDKN2A TP53	7.12e-05	2	294	2	19851197
Pubmed	Atypical leiomyomas of the uterus with long-term follow-up after myomectomy with immunohistochemical analysis for p16INK4A, p53, Ki-67, estrogen receptors, and progesterone receptors.	CDKN2A TP53	7.12e-05	2	294	2	19851199
Pubmed	Kruppel-like factor 4 mediates p53-dependent G1/S cell cycle arrest in response to DNA damage.	KLF4 TP53	7.12e-05	2	294	2	12427745
Pubmed	Modeling the response of a tumor-suppressive network to mitogenic and oncogenic signals.	CDKN2A TP53	7.12e-05	2	294	2	28484034
Pubmed	Association of the OCTN1/1672T variant with increased risk for colorectal cancer in young individuals and ulcerative colitis patients.	SLC22A4 SLC22A5	7.12e-05	2	294	2	21793125
Pubmed	Human papillomavirus 16 is an aetiological factor of scrotal cancer.	CDKN2A TP53	7.12e-05	2	294	2	28376081
Pubmed	Human leucine-rich repeat kinase 1 and 2: intersecting or unrelated functions?	LRRK2 LRRK1	7.12e-05	2	294	2	22988872
Pubmed	Expression of p16 and cervical infection with high-risk human papillomavirus are not related to p53 activity in cervical intraepithelial neoplasia.	CDKN2A TP53	7.12e-05	2	294	2	18021213
Pubmed	Identification of TRIML2, a novel p53 target, that enhances p53 SUMOylation and regulates the transactivation of proapoptotic genes.	TRIML2 TP53	7.12e-05	2	294	2	25256710
Pubmed	Complementary effects of platelet-derived growth factor autocrine stimulation and p53 or Ink4a-Arf deletion in a mouse glioma model.	CDKN2A TP53	7.12e-05	2	294	2	12907595
Pubmed	Potentiation of neuronal activity by tonic GluD1 current in brain slices.	GLUD1 GLUD2	7.12e-05	2	294	2	37154294
Pubmed	Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53.	UBE3A TP53	7.12e-05	2	294	2	8380895
Pubmed	SLC22A4 and SLC22A5 gene polymorphisms and Crohn's disease in the Chinese Han population.	SLC22A4 SLC22A5	7.12e-05	2	294	2	19659785
Pubmed	Survey of familial glioma and role of germline p16INK4A/p14ARF and p53 mutation.	CDKN2A TP53	7.12e-05	2	294	2	20455025
Pubmed	p53 and p16 expression profiles in vulvar cancer: a translational analysis by the Arbeitsgemeinschaft Gynäkologische Onkologie Chemo and Radiotherapy in Epithelial Vulvar Cancer study group.	CDKN2A TP53	7.12e-05	2	294	2	33453182
Pubmed	Delayed ageing through damage protection by the Arf/p53 pathway.	CDKN2A TP53	7.12e-05	2	294	2	17637672
Pubmed	Genetic Analysis of LRRK1 and LRRK2 Variants in Essential Tremor Patients.	LRRK2 LRRK1	7.12e-05	2	294	2	29812962
Pubmed	Immortalization of human mammary epithelial cells is associated with inactivation of the p14ARF-p53 pathway.	CDKN2A TP53	7.12e-05	2	294	2	14966292
Pubmed	Dynamic and redundant regulation of LRRK2 and LRRK1 expression.	LRRK2 LRRK1	7.12e-05	2	294	2	18045479
Pubmed	Identification of somatic and germ-line DICER1 mutations in pleuropulmonary blastoma, cystic nephroma and rhabdomyosarcoma tumors within a DICER1 syndrome pedigree.	DICER1 TP53	7.12e-05	2	294	2	28222777
Pubmed	Heterodimerization of Lrrk1-Lrrk2: Implications for LRRK2-associated Parkinson disease.	LRRK2 LRRK1	7.12e-05	2	294	2	20144646
Pubmed	Variants in the LRRK1 gene and susceptibility to Parkinson's disease in Norway.	LRRK2 LRRK1	7.12e-05	2	294	2	17324517
Pubmed	Frequent mutations in TP53 and CDKN2A found by next-generation sequencing of head and neck cancer cell lines.	CDKN2A TP53	7.12e-05	2	294	2	22911296
Pubmed	Thymic adult T-cell acute lymphoblastic leukemia stratified in standard- and high-risk group by aberrant HOX11L2 expression: experience of the German multicenter ALL study group.	TLX1 TLX3	7.12e-05	2	294	2	18368072
Pubmed	Correlation between indoleamine 2,3 dioxygenase mRNA and CDKN2A/p16 mRNA: a combined strategy to cervical cancer diagnosis.	CDKN2A IDO1	7.12e-05	2	294	2	27761872
Pubmed	TP53 mutations and CDKN2A mutations/deletions are highly recurrent molecular alterations in the malignant progression of sinonasal papillomas.	CDKN2A TP53	7.12e-05	2	294	2	33203919
Pubmed	Expression and functional analysis of intestinal organic cation/L-carnitine transporter (OCTN) in Crohn's disease.	SLC22A4 SLC22A5	7.12e-05	2	294	2	22325173
Pubmed	Glutamate dehydrogenase deficiency disrupts glutamate homeostasis in hippocampus and prefrontal cortex and impairs recognition memory.	GLUD1 GLUD2	7.12e-05	2	294	2	31898404
Pubmed	Birth and adaptive evolution of a hominoid gene that supports high neurotransmitter flux.	GLUD1 GLUD2	7.12e-05	2	294	2	15378063
Pubmed	Negative feedback by IRE1β optimizes mucin production in goblet cells.	ERN2 MUC2	7.12e-05	2	294	2	23386727
Pubmed	Cdkn2a suppresses metastasis in squamous cell carcinomas induced by the gain-of-function mutant p53(R172H).	CDKN2A TP53	7.12e-05	2	294	2	27447534
Pubmed	Do different disorders in cell cycle regulation account for different biological behavior of urothelial and sinonasal inverted papillomas?	CDKN2A TP53	7.12e-05	2	294	2	18334838
Pubmed	Alterations in the tumor suppressor gene p16(INK4A) are associated with aggressive behavior of penile carcinomas.	CDKN2A TP53	7.12e-05	2	294	2	21085986
Pubmed	p53 Deficiency leads to compensatory up-regulation of p16INK4a.	CDKN2A TP53	7.12e-05	2	294	2	19240179
Pubmed	Mutational Status of CDKN2A and TP53 Genes in Laryngeal Squamous Cell Carcinoma.	CDKN2A TP53	7.12e-05	2	294	2	25149524
Pubmed	A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18.	UBE3A TP53	7.12e-05	2	294	2	1661671
Pubmed	Genetic alterations of INK4alpha/ARF locus and p53 in human hepatocellular carcinoma.	CDKN2A TP53	7.12e-05	2	294	2	12168936
Pubmed	Transcriptomic responses in mouse brain exposed to chronic excess of the neurotransmitter glutamate.	GLUD1 GLUD2	7.12e-05	2	294	2	20529287
Pubmed	Prostaglandin F2alpha promotes muscle cell survival and growth through upregulation of the inhibitor of apoptosis protein BRUCE.	BIRC6 NFATC2	7.12e-05	2	294	2	18566603
Pubmed	Dual inactivation of RB and p53 pathways in RAS-induced melanomas.	CDKN2A TP53	7.12e-05	2	294	2	11238948
Pubmed	The nuclear receptor NR4A1 induces a form of cell death dependent on autophagy in mammalian cells.	NR4A1 TP53	7.12e-05	2	294	2	23071566
Interaction	TOP3B interactions	VWA5B2 SREBF1 CARD10 KLF4 FHIP1B TTC3 ZZEF1 BIRC6 AHDC1 TNRC18 WIZ FAM120C RRP12 AP1G2 ZER1 CIAO2A SIPA1L2 BRAT1 DPH2 RANBP10 FRAS1 SH3RF1 SZT2 RNPEPL1 UBR4 HIP1R PAPLN LRRK1 THOC2 TEP1 TBC1D17 INTS5 NADSYN1 CELSR3 TRIM28 BTBD7 ANKRD34A UNK DISP2 DOT1L CABIN1 SPEN DHX34 TP53 HTT	3.99e-07	1470	279	45	int:TOP3B
GeneFamily	C2-set domain containing\|Immunoglobulin like domain containing\|Scavenger receptors	MAG BTN1A1 NECTIN1 SIGLEC12	4.84e-04	40	166	4	592
GeneFamily	Cyclins\|P-TEFb complex	CCNT1 CCNT2	4.97e-04	4	166	2	1281
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ABL2 NR4A1 ARID5A MED12L SIGLEC12 DOCK10 RASGEF1C GAB3 ARHGAP27 DOT1L	8.51e-07	199	293	10	b0a906586e58009f5ed9272fc29ba28e49c85ee6
ToppCell	Globus_pallidus\|World / BrainAtlas - Mouse McCarroll V32	MAG SZT2 RNPEPL1 DOCK10 ITGA10 SIDT2 UNK DOT1L	1.90e-06	126	293	8	44b63f945d5bedf1a2ca1810e7e100276ea9dd89
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_endothelial_cell_-_unspecif\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CARD10 ZP3 ARID5A FZD9 ADAD2 RECQL4 GNRH1 NPY5R ACKR1	2.38e-06	174	293	9	4d8c4a7d8f4972da68cebe0a79eb1a14ec546121
ToppCell	COVID-19-APC-like-Dendritic_cells\|COVID-19 / group, cell type (main and fine annotations)	IDO1 DISC1 NFATC2 MED12L STIM2 DOCK10 LRRK1 CD1A CSF2RA	3.60e-06	183	293	9	703364836b42aa6ac6c68b42b700ac23c4a1afc7
ToppCell	droplet-Liver-Npc-21m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDKN2A ZNF142 RFTN2 SIPA1L2 CCNT2 SPEN	1.00e-05	75	293	6	7f3be37cc378ee115fcb4b0eb9653fc77447aa0a
ToppCell	Endothelial-B-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	RAMP3 RNF112 CARD10 RFTN2 FZD9 PEAR1 P3H3 PLA2R1	1.39e-05	165	293	8	10087d8bd2985906ef19547fe77eb178ae5e1638
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AHDC1 FZD9 NRK WNK4 NID2 ITGA10 CHADL GTF2H4	1.46e-05	166	293	8	81c546c6d847e49e662b81e71992ca0f7a99e890
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte-Chondrocyte_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AHDC1 FZD9 NRK WNK4 NID2 ITGA10 CHADL GTF2H4	1.46e-05	166	293	8	37794a84601a2a949d579663d4a4bb8bc8fb5923
ToppCell	5'-Adult-LargeIntestine-Epithelial-goblet-Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SYTL2 FAM83E KLF4 WNK4 KLK15 ERN2 DISP2 MUC2	1.81e-05	171	293	8	48125d825ca2d7ef34564250f5b47d2a579e03c9
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATP8A2 CARD10 PRDM8 TENT4B RANBP6 POLR3C LLGL1 TRIM67	1.96e-05	173	293	8	4968712af1cca8c932abd3323631d7dcaffd4a66
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-goblet-BEST2+_Goblet_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SYTL2 KLF4 WNK4 KLK15 ERN2 MAMDC4 DISP2 MUC2	2.51e-05	179	293	8	c833ded1f9e87be2ba2037820d92a389560b711c
ToppCell	droplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM88 NEU3 RASIP1 DLC1 JCAD COPG2 DISP2 ELK3	2.72e-05	181	293	8	4df7972f88117108698efd06b124b232f8588981
ToppCell	droplet-Liver-hepatocytes-3m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM88 NEU3 RASIP1 DLC1 JCAD COPG2 DISP2 ELK3	2.72e-05	181	293	8	cbb530566893281289026bfd93adf721decd4ca3
ToppCell	COVID-19-APC-like\|COVID-19 / group, cell type (main and fine annotations)	IDO1 DISC1 NFATC2 MED12L DOCK10 LRRK1 CD1A CSF2RA	2.94e-05	183	293	8	b8f5afaf9ff1b2b1bc60be58654d1b23859dafa9
ToppCell	Fetal_29-31_weeks-Mesenchymal-chondrocyte-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	GDF5 RFTN2 NEDD4 FZD9 SERPINE2 NRK WNK4 ITGA10	3.17e-05	185	293	8	8ed10ba581849c9c4ac4397226be2b62b4b3b900
ToppCell	Endothelial-A-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	RAMP3 RFTN2 RASIP1 SERPINE2 PEAR1 JCAD SORCS3 ACKR1	3.17e-05	185	293	8	ae49c61f6ecf128fe2a958b8c75c83688da75f59
ToppCell	Fetal_29-31_weeks-Mesenchymal-chondrocyte\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	GDF5 RFTN2 NEDD4 FZD9 SERPINE2 NRK WNK4 ITGA10	3.17e-05	185	293	8	b8052cebb73f41abe6faf0aa847be7c8ef23ae94
ToppCell	wk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	QRICH2 IRF9 ZER1 FRAS1 HIP1R MAMDC4 WDR97 MTR	3.17e-05	185	293	8	636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCell	Substantia_nigra-Neuronal\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	TTC3 LRFN5 FBXO41 CELSR3 ANKRD34A DISP2 ACKR1 MAPK8IP2	3.30e-05	186	293	8	3f889083fcffe516388e9b03a5e23af2010ced33
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-fenestrated_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM88 RAMP3 ATP8A2 KLF4 RASIP1 SERPINE2 DLC1 ELK3	3.43e-05	187	293	8	f2a0d0829dc88aa93bfb2eebbbc0ef156a9cba84
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-Pecam____fenestrated_capillary_endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM88 RAMP3 ATP8A2 KLF4 RASIP1 SERPINE2 DLC1 ELK3	3.43e-05	187	293	8	fa71f9220b288ed6a1d06f347fec42649aac1f13
ToppCell	PND07-28-samps-Mesenchymal-Matrix_fibroblast\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	VGLL3 MAP3K20 NEDD4 SERPINE2 DLC1 RCAN1 NFKBIZ CAMK1G	3.69e-05	189	293	8	dc5164591dea45b420798b94dda211be03daa70c
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	GDF5 FZD9 NRK DIO2 WNK4 MXRA5 ITGA10 CHADL	3.98e-05	191	293	8	273c4a757292a9301de0eaeacdec91c9866be229
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	GDF5 FZD9 NRK DIO2 WNK4 MXRA5 ITGA10 CHADL	3.98e-05	191	293	8	f9a46956778a8773d6656340ecf5d218376d79c2
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM88 RAMP3 RNF112 KLF4 RASIP1 DLC1 ELK3 ACKR1	4.29e-05	193	293	8	daefbfd3a3dd1351fbe94b9abfd807db44d56c24
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RAMP3 RASIP1 DLC1 JCAD OVCH1 ARHGAP28 ELK3 ACKR1	4.29e-05	193	293	8	1f978e102a029a6beb10913052cd0a20c7253e8e
ToppCell	3'-Adult-LargeIntestine-Epithelial-goblet\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SYTL2 NR4A1 KLF4 WNK4 KLK15 ERN2 DISP2 MUC2	4.44e-05	194	293	8	1a188e52f2f0b6eca3e8d4a4671d9beab0fbbb88
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_prolif-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	VGLL3 RNASEH2C PEAR1 NID2 MXRA5 TDRD1 HPDL HASPIN	4.44e-05	194	293	8	b8aa48d7774e4da3351ee2177eb694fcfec7cbc3
ToppCell	droplet-Kidney-nan-21m-Endothelial-fenestrated_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM88 RAMP3 ATP8A2 KLF4 RASIP1 SERPINE2 DLC1 ELK3	4.61e-05	195	293	8	37d22a6448db1f83d098018fbb75a6dd8d9be302
ToppCell	droplet-Kidney-nan-21m-Endothelial-Pecam____fenestrated_capillary_endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM88 RAMP3 ATP8A2 KLF4 RASIP1 SERPINE2 DLC1 ELK3	4.61e-05	195	293	8	37592b7ad912b381b1edc77f4032983f26e0aa5b
ToppCell	3'-Adult-LargeIntestine-Epithelial-goblet-BEST2+_Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SYTL2 NR4A1 KLF4 WNK4 KLK15 ERN2 DISP2 MUC2	4.61e-05	195	293	8	3365768101454060b9ea96ef6b426c76c150bc8f
ToppCell	5'-Adult-LargeIntestine-Epithelial-goblet\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SYTL2 FAM83E KLF4 WNK4 KLK15 ERN2 DISP2 MUC2	4.78e-05	196	293	8	847b3377f463bfded046eec63cc1b547f3dc33c1
ToppCell	COVID-19-lung-Capillary_Aerocytes\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RAMP3 IDO1 NEDD4 RASIP1 SIPA1L2 JCAD ITGA10 SHROOM2	4.78e-05	196	293	8	49cc0a2b9739abad61dff7292ea0b14d28ff35c4
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	VWA5B2 TMEM88 RAMP3 ADAD2 RASIP1 PEAR1 JCAD NID2	4.95e-05	197	293	8	a312d9cf4ced949307eb9620be4eed926300b892
ToppCell	5'-Adult-LargeIntestine-Epithelial-goblet-BEST2+_Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SYTL2 FAM83E KLF4 WNK4 KLK15 ERN2 DISP2 MUC2	4.95e-05	197	293	8	d624f3a105b19f19a0dd253ce8de3ed13adc1f01
ToppCell	Control_saline-Hematopoietic_Erythro-Megakary-Erythro-Mega\|Control_saline / Treatment groups by lineage, cell group, cell type	MED12L ZER1 RANBP10 TSPAN32 PPBP PNKD SLC22A4 ACKR1	5.13e-05	198	293	8	1a39a98beef68e1e6d3adc25270a3336fcc5baf4
ToppCell	Control_saline-Hematopoietic_Erythro-Megakary\|Control_saline / Treatment groups by lineage, cell group, cell type	MED12L ZER1 RANBP10 TSPAN32 PPBP PNKD SLC22A4 ACKR1	5.13e-05	198	293	8	cfc2a860bae883299987d3e374d0476ca20e1bdd
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TMEM88 RAMP3 CARD10 ADAD2 RASIP1 JCAD ELK3 ACKR1	5.13e-05	198	293	8	4a70a1ab40fe30b90acd97e4e36067db62acc905
ToppCell	droplet-Trachea\|droplet / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEDD4 FZD9 SERPINE2 RCAN1 P3H3 TMPRSS6 ITGA10 CHADL	5.32e-05	199	293	8	1c7d30765ddb2291967da5d15664c6238c680c1d
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	VGLL3 ANKRD53 PEAR1 JCAD NID2 ITGA10 CAMK1G ARHGAP28	5.32e-05	199	293	8	dfc5c7a4a093baa7158dd8d4d29a870d9c469a3f
ToppCell	droplet-Trachea\|droplet / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NEDD4 FZD9 SERPINE2 RCAN1 P3H3 TMPRSS6 ITGA10 CHADL	5.32e-05	199	293	8	b9038a1ccf3ef3123e2e39afbe6213c363437443
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	VGLL3 ANKRD53 PEAR1 JCAD NID2 ITGA10 CAMK1G ARHGAP28	5.32e-05	199	293	8	c1760581c34b81d1d92c67500a1c8944e9cc6dad
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_4\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	ABL2 RASIP1 SH3RF1 WNT9A ANKRD34A CYP4F11	5.47e-05	101	293	6	657d3994b93e2fbb1ff96f701ff2ea6665e5a15c
ToppCell	proximal-Endothelial\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TMEM88 RAMP3 CARD10 ARID5A RASIP1 JCAD ELK3 ACKR1	5.51e-05	200	293	8	970dac1b11ae8f4adb26634717064289967b4bde
ToppCell	proximal-3-Endothelial\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TMEM88 RAMP3 CARD10 ARID5A RASIP1 JCAD ELK3 ACKR1	5.51e-05	200	293	8	90c36cfb9632a3bdc9a335b2193f6b08aba35208
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Neuroepithelial\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	DISC1 SYTL2 NR4A1 IRF9 PEAR1 NFKBIZ ZBTB7B PLA2R1	5.51e-05	200	293	8	25f4c051c2e869481f33c22ad54de97efac444ad
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Neuroepithelial-Proteoglycan-expressing_cell\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	DISC1 SYTL2 NR4A1 IRF9 PEAR1 NFKBIZ ZBTB7B PLA2R1	5.51e-05	200	293	8	da45a85a4667965b24ba824af871157af5b4cd19
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Neuronal-Intermediate\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	VWA5B2 MTHFD2 C8orf48 MAP3K15 NID2 MXRA5 TSPAN32 FAM98C	5.51e-05	200	293	8	fe772d98c461c973dfc082e1fc50117c27ced804
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Neuroepithelial\|6m / Sample Type, Dataset, Time_group, and Cell type.	VGLL3 NR4A1 KLF4 DLC1 NRK NID2 NFKBIZ ELK3	5.51e-05	200	293	8	2cc98abf11f5b58707de45a2282f03d47f00f035
ToppCell	Control_saline-Endothelial-Endothelial\|Control_saline / Treatment groups by lineage, cell group, cell type	KLF4 NEDD4 RASIP1 DLC1 SIPA1L2 JCAD STIM2 ELK3	5.51e-05	200	293	8	e77eba6172cabf85b8028638ed35299f2f079cd8
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Neuroepithelial-Proteoglycan-expressing_cell\|6m / Sample Type, Dataset, Time_group, and Cell type.	VGLL3 NR4A1 KLF4 DLC1 NRK NID2 NFKBIZ ELK3	5.51e-05	200	293	8	0f7431f670f3a175377cefae3479403a881bb8fb
ToppCell	Control_saline-Endothelial-Endothelial-Activated_Alv_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	KLF4 NEDD4 RASIP1 IRF9 DLC1 HERC6 SIPA1L2 JCAD	5.51e-05	200	293	8	be55cef682ba87250dad97689332c8820b3a7420
ToppCell	Control_saline-Endothelial\|Control_saline / Treatment groups by lineage, cell group, cell type	KLF4 NEDD4 RASIP1 DLC1 SIPA1L2 JCAD STIM2 ELK3	5.51e-05	200	293	8	3372c488a39fe812fa94e4f0564594186fea3db5
ToppCell	356C-Myeloid-Macrophage-SPP1+_Macrophage_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	TMEM88 ABL2 RAMP3 DMXL1 RCAN1 GTF2H4 CERS1	5.90e-05	149	293	7	a6c24d8f3b5f08587f0a12cd63d166b68ea000c7
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-3\|TCGA-Brain / Sample_Type by Project: Shred V9	CCDC168 TASOR2 SZT2 UBR4 HEATR5A GSC2 SPEN	5.90e-05	149	293	7	768877bade04ca0321593b8470b5011ad8270431
ToppCell	Entopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Rgs5Acta2.Junb_(Mural,_IEG+)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	CAND2 C3orf62 NEU3 NR4A1 ASB10 NFKBIZ PLA2R1	7.87e-05	156	293	7	029ba0832ee9c4a2c85620e4df2260e02d86b45c
ToppCell	Entopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Rgs5Acta2.Junb_(Mural,_IEG+)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	CAND2 C3orf62 NEU3 NR4A1 ASB10 NFKBIZ PLA2R1	7.87e-05	156	293	7	5df19a235843829f5a1a90ca21b0964ef8b4e115
ToppCell	356C-Myeloid-Macrophage-SPP1+_Macrophage_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	TMEM88 ABL2 RAMP3 IDO1 NR4A1 NFKBIZ ELK3	8.20e-05	157	293	7	7ceae5fe00c91d4feb8c314d3a31f027c03fa56f
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM88 ARID5A FZD9 ADAD2 RECQL4 NPY5R ACKR1	8.53e-05	158	293	7	0c3907e3395ed01b3fd7b75fdca6feadc890ea85
ToppCell	droplet-Marrow-BM-30m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TREX1 MAP3K20 HERC6 MED7 GNRH1 UBR4 POLR3C	9.97e-05	162	293	7	75df7ff779a3b9159ba97d852da1f8df650b9ce5
ToppCell	Adult-Immune-dendritic_cell\|Adult / Lineage, Cell type, age group and donor	IDO1 MED12L DOCK10 LRRK1 TDRD1 CSF2RA HASPIN	1.12e-04	165	293	7	073f52698dac1fe4edd7410865f81b30e1c7196a
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GDF5 GCKR WNT9A HPDL CELSR3 FIBCD1 DISP2	1.20e-04	167	293	7	95b3b5ba3414729f0460a26a0deca48de0cbe33e
ToppCell	Thalamus-Macroglia-POLYDENDROCYTE\|Thalamus / BrainAtlas - Mouse McCarroll V32	MAG NCBP1 CHADL USP16 DICER1 LLGL1 MROH2B	1.20e-04	167	293	7	1e144c03409df94ccd39760842590e8ea7487e29
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GDF5 GCKR WNT9A HPDL CELSR3 FIBCD1 DISP2	1.20e-04	167	293	7	3dfec2fcc36caa6e394efae5e540a6fa28759977
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GDF5 GCKR WNT9A HPDL CELSR3 FIBCD1 DISP2	1.20e-04	167	293	7	9480739587d51e67a281778b9bddd7b5ffc3ad92
ToppCell	5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TMEM88 RAMP3 RASIP1 SIPA1L2 JCAD CDH24 ACKR1	1.40e-04	171	293	7	b3e6e31dfe3623b960ccf692fdbd236fa4039923
ToppCell	facs-Heart-LV-3m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RTP1 ATP8A2 FAM83E LDHD WNK4 PCDHB8 DICER1	1.45e-04	172	293	7	f2c17c49b375b28ad47dc6cabda62f1c238023dd
ToppCell	facs-Heart-LV-3m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RTP1 ATP8A2 FAM83E LDHD WNK4 PCDHB8 DICER1	1.45e-04	172	293	7	6ab4f01098dddb789df298ddf97b3c384405ee6c
ToppCell	droplet-Liver-Hepatocytes-21m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NHLRC1 MAG ABL2 CAMTA2 MTR SSH2 NHEJ1	1.45e-04	172	293	7	1627fa7035b0e0bbc82a1c0f000d8231254c680a
ToppCell	droplet-Liver-Hepatocytes-21m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NHLRC1 MAG ABL2 CAMTA2 MTR SSH2 NHEJ1	1.45e-04	172	293	7	574ebdf36e45222bcd907cd2c2ee7ff50ed4573a
ToppCell	facs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l27\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TMEM88 RAMP3 IDO1 NEU3 RASIP1 LIPE ELK3	1.50e-04	173	293	7	ad9777e4ae70b11676ec735eb6db91776ca0cb19
ToppCell	5'-Adult-LymphNode-Hematopoietic-T_cells-TRGV2_gdT\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TTC14 ITGAD PRDM8 RECQL4 GNRH1 DOCK10 TSPAN32	1.50e-04	173	293	7	79d11f94a8f6a420c18c2fef0da77e9af3204765
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAND2 RTBDN ITGAD ANKRD53 LRFN4 FRAS1 USP16	1.55e-04	174	293	7	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l28\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GDF5 FZD9 FANCG ASB7 RRP12 MAP3K15 RRP8	1.61e-04	175	293	7	aa168aeb9ad71aa6c0c28a0657c9eb92a0b28183
ToppCell	droplet-Pancreas-Exocrine-18m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM88 RAMP3 TLX1 DLC1 APOA5 LIPE ACKR1	1.67e-04	176	293	7	eb63eb2c301e785196ccadac74a2940b2c524c62
ToppCell	wk_08-11-Mesenchymal-Chondrocyte\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	GDF5 FZD9 NRK WNK4 MXRA5 ITGA10 CHADL	1.67e-04	176	293	7	1af28b701c4598ce761f85adbd5d79e4918d265a
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	RNF112 RFTN2 RYR2 KIAA1210 NID2 MXRA5 PAPLN	1.73e-04	177	293	7	cdfd2f0ee2f692271b1525e414b0f645cdadb1f6
ToppCell	5'-Adult-Appendix-Hematopoietic-Myeloid-cDC1\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IDO1 NEU3 FBXO41 LRRK1 GDF7 CSF2RA GAB3	1.73e-04	177	293	7	345cebc19f93970a9a46be139208b300081f5493
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|356C / Donor, Lineage, Cell class and subclass (all cells)	RNF112 RFTN2 RYR2 KIAA1210 NID2 MXRA5 PAPLN	1.73e-04	177	293	7	db222faaecbe5600da39277243c4e7e764eb63c9
ToppCell	droplet-Limb_Muscle-nan-24m-Endothelial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INPP4A KIAA0753 GRK4 PPBP HPDL FLAD1 RASGEF1C	1.79e-04	178	293	7	f2002a5c4758d0af6c1880ca12f0af0d5e8888e4
ToppCell	wk_15-18-Mesenchymal-Chondrocyte-ASPN+_chondrocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	GDF5 FZD9 NRK DIO2 ITGA10 TEP1 PLA2R1	1.79e-04	178	293	7	a55130670aa95a87b833dd3cd2de461d779e4c06
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Calb1-Excitatory_Neuron.Slc17a7-Slc17a6.Calb1-Rorb-Il1rapl2_(Layer_5b)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	DISC1 ANKMY1 NUTM1 FRAS1 GSC2	1.83e-04	80	293	5	402aba070f0728ebda9db7a8fa85441533755ff4
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-B_atypical-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ZC3H14 BFAR AHDC1 DMXL1 WIZ LLGL1 UNK	1.85e-04	179	293	7	5be883d7d0be3180bb9844e4a757f0dd247294e4
ToppCell	ASK454-Endothelial-Lymphatic\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	CAND2 NCAPG2 PEAR1 NID2 PLA2R1 FAM193A ELK3	1.85e-04	179	293	7	fd84a79f76a01c0377dff5b20016b004d369f96f
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	VGLL3 MAP3K20 CARD10 NEDD4 FRMPD1 DOCK10 RIPPLY1	1.85e-04	179	293	7	3b0f8781232e1d42b6f8913bc989a14b3f978e79
ToppCell	390C-Lymphocytic-ILC-ILC-1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CHKB ITGAD KLF4 RRP12 CHADL WDR97 SLC22A5	1.85e-04	179	293	7	3edcd1356e49b1f5514c585861999e079ca5e579
ToppCell	10x5'v1-week_17-19-Hematopoietic-MK-early_MK\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	SERPINE2 DLC1 NUTM2B MED12L TSPAN32 PPBP ARHGEF33	1.85e-04	179	293	7	d5b9c610c1519804b1753fed1b505293ea590867
ToppCell	droplet-Heart-nan-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM88 RASIP1 GVINP1 JCAD BTBD7 ELK3 ARHGAP27	1.98e-04	181	293	7	92d44892bb15771f0ab5fe61879b204b0acbd9b3
ToppCell	Control_saline-Hematopoietic_Myeloid-Dendritic_cells-mDC\|Control_saline / Treatment groups by lineage, cell group, cell type	IDO1 WWC2 AIRE PPP2R1B INTS5 ARSD DOT1L	1.98e-04	181	293	7	818ac31a718e9b29feb4c4eecbc339e6af45254a
ToppCell	droplet-Heart-nan-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM88 RASIP1 GVINP1 JCAD LIPE ELK3 ARHGAP27	2.05e-04	182	293	7	81279877b920b5a1bc991a07d3031d6458700fe3
ToppCell	metastatic_Lymph_Node-Myeloid_cells-CD1c+_DCs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	IDO1 NR4A1 KLF4 ASB10 CD1A CSF2RA ADGRD2	2.05e-04	182	293	7	551d301adfb4d5046c5f60f6996450621b04e9b2
ToppCell	E16.5-samps-Endothelial-Immature_fetal_endothelial-Intermediate_Endothelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	TMEM88 KLF4 RYR2 RASIP1 JCAD SHROOM2 ARHGAP27	2.05e-04	182	293	7	fec1caf867b1dc87b24504d895ee1a27df78062e
ToppCell	droplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM88 RASIP1 PEAR1 JCAD SH3RF1 PLA2R1 ELK3	2.05e-04	182	293	7	b1ec2015aad1181eac1bbf8d48ad6f2f7ed24a01
ToppCell	wk_08-11-Mesenchymal-Chondrocyte-Resting_chondrocyte\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	NEDD4 FZD9 NRK DIO2 WNK4 ITGA10 CHADL	2.05e-04	182	293	7	00a148b1e499bf16325491536d187d4dd6b70c06
ToppCell	Control-Endothelial-Endothelial-Activated_Alv_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RAMP3 KLF4 NEDD4 RASIP1 HERC6 SIPA1L2 JCAD	2.12e-04	183	293	7	e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-goblet-Goblet_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SYTL2 FAM83E KLF4 WNK4 KLK15 ERN2 MUC2	2.19e-04	184	293	7	886d2d9bf2fe31207f17e3edc309ef44029924e1
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-goblet\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SYTL2 FAM83E KLF4 WNK4 KLK15 ERN2 MUC2	2.19e-04	184	293	7	936b39377eebea3961d702532779f6cd27953be7
ToppCell	facs-Liver-Non-hepatocytes-3m-Lymphocytic-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VGLL3 MTHFD2 ATP8A2 SYTL2 GVINP1 PIM2 DOCK10	2.19e-04	184	293	7	8fc047977fad38fcd26eebcc279a688efd342ed8
ToppCell	metastatic_Brain-Endothelial_cells-Stalk-like_ECs\|metastatic_Brain / Location, Cell class and cell subclass	TMEM88 GCKR RASIP1 JCAD ITGA10 DISP2 ELK3	2.26e-04	185	293	7	ad52970e88e8947ef256095bd4b40229b912d58a
ToppCell	COVID-cycling-\|COVID / Condition, Cell_class and T cell subcluster	C8orf48 NCAPG2 RECQL4 PEAR1 PLA2R1 HASPIN ACKR1	2.26e-04	185	293	7	eb74b8d36f7b749e04bc2ed4b36f7e1ac7bb6d5f
Drug	Pentylenetetrazole [54-95-5]; Up 200; 29uM; MCF7; HT_HG-U133A	NR4A1 ZZEF1 SLC22A7 WIZ KLK15 SZT2 FRMPD1 RRP8 TEP1 ERN2 HIPK3 PPP2R1B ZNF646	1.62e-06	198	289	13	2255_UP
Drug	2-Chloropyrazine [14508-49-7]; Down 200; 35uM; MCF7; HT_HG-U133A	RYR2 IRF9 SERPINE2 AP1G2 PIM2 RNPEPL1 HIP1R TDRD1 CCNT2 BTBD7 CABIN1 DHX34	7.51e-06	194	289	12	3570_DN
Drug	Gabexate mesilate [56974-61-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A	DOHH INPP4A SYTL2 WIZ RRP12 NUP160 PIM2 SZT2 TBC1D17 CCNT2 CABIN1 DHX34	8.34e-06	196	289	12	7357_DN
Drug	Colistin sulfate [1264-72-8]; Down 200; 3uM; HL60; HT_HG-U133A	INPP4A RYR2 NUP160 MRTFA TBC1D17 PITPNM1 CCNT2 PPP2R1B BTBD7 CXXC4 DHX34 HTT	8.78e-06	197	289	12	2491_DN

Protein segments in the cluster

Peptide	Gene	Start	Entry
CRVQPITSSHLALPF	TDRD1	1036	Q9BXT4
DFAHCLLPPLENLAT	PPP2R1B	96	P30154
TSKEHRPLAQPACLT	MAMDC4	876	Q6UXC1
CLLERDPIPAAHSFV	BRAT1	246	Q6PJG6
DPIPAAHSFVDLLLC	BRAT1	251	Q6PJG6
AHSFVDLLLCVARSP	BRAT1	256	Q6PJG6
ILADSCHDPPTLSRA	ADAD2	426	Q8NCV1
ANLTLPERADPHALC	CARD10	711	Q9BWT7
SHELSPFRALCLGPS	AGPAT4-IT1	166	Q9H0P7
PTSFDSALRHRLCPA	ARID5A	556	Q03989
QHLAAAPLCTPSRAA	ARSD	81	P51689
VAHACLHPLEPLLDT	CCNT2	106	O60583
TPLHLSALRDDVLCA	ASB7	216	Q9H672
IEPLPFTLAHERCIS	BIRC6	2316	Q9NR09
RLLQHPSICSDPTEE	ABL2	991	P42684
AELPCRLSPNASAEH	BTN1A1	46	Q13410
NVSCASFHPELPIII	COPB2	231	P35606
CALRSHLEGSLPQAL	ASB10	431	Q8WXI3
PLASCHFPIDQLQLS	GVINP1	296	Q7Z2Y8
HPSIIFIDELDALCP	SPATA5	446	Q8NB90
HERPESLLAPTQFCA	ARHGEF33	546	A8MVX0
ELSSVFLPPCAQLLH	AP1G2	171	O75843
AHTPCSALEPAAALE	CAMTA2	406	O94983
SSPLLGDHRCLVPFR	CD300LD-AS1	56	Q96MU5
ACAHALEALATLLRP	DPH2	156	Q9BQC3
LFCHQATRTLLPSLP	ACKR1	306	Q16570
EPLFRQLAKCVSSPH	PPP2R5D	401	Q14738
HAPASPARLSRCVQV	APOA5	216	Q6Q788
CLHPQESLPDTRSEA	CCNT1	111	O60563
SCVPPDDALSLHLRG	DOT1L	661	Q8TEK3
FLGRTEAACLSAPHL	AHDC1	1491	Q5TGY3
LLFRCSLPDHLPSVG	CHKB	81	Q9Y259
RKLLESTPSPVVFCH	CHKB	226	Q9Y259
FTHLAPKCRTRELPD	DICER1	646	Q9UPY3
HEDPRCLSRPFSLLA	DISC1	256	Q9NRI5
HDLAELPVSSPLCHA	DMXL1	2511	Q9Y485
HLCPHPDRLSRVAFS	DISP2	1041	A7MBM2
IRFTPTVPHCSLATL	CIAO2A	81	Q9H5X1
AILAHCNLRLPGSSD	FAM193A	1181	P78312
RPACLAALQAHADDP	DOHH	251	Q9BU89
HPTAPCIQEFLTLLA	ATP8A2	491	Q9NTI2
PSHLACPDVLNLSLD	ATG4B	356	Q9Y4P1
RAFHLACLSPPLREI	AIRE	316	O43918
HLCPDSPESSRLSLE	ANKRD34A	346	Q69YU3
LQDLPSATIACHLDP	RCAN1	61	P53805
TFLNAPDILPRHCTV	RASIP1	426	Q5U651
DAASVRATHPIPAAC	RANBP10	86	Q6VN20
FSNCTVDRVHLEDPP	RAMP3	101	O60896
LQTALPPALFSCHLL	NFILZ	186	A0A5F9ZHS7
LSCDRPLETPVTGHA	QRICH2	1426	Q9H0J4
AESRHLPEECRLSPS	RFTN2	441	Q52LD8
SPERPLHLSFTHLVC	P3H3	551	Q8IVL6
ACSELHTPSLDRKPN	INPP4A	51	Q96PE3
HFFCDIPPLLLLSRS	OR5W2	176	Q8NH69
PVLARCTLHPNDSLA	LLGL1	631	Q15334
EFLCEPPLITRHTHE	LRFN5	281	Q96NI6
RSLHSLLVDVPAFAC	NR4A1	491	P22736
SACHLPFSLPFLKRL	C8orf48	291	Q96LL4
RSFHPSVDARLQCIP	ANKRD53	351	Q8N9V6
VSFLQLHPREDACIP	TENT4B	291	Q8NDF8
ACHPQPLLRSFLLNT	FHIP1B	771	Q8N612
LAEDSCLGRHSPVPR	NFATC2	226	Q13469
PAHRNFLCSLESNPS	IDO1	301	P14902
TCHLLDFASPERPLV	DIO2	111	Q92813
LEEVLSSRDCHPALP	KLF4	321	O43474
EKPLACTAHAPERFL	FRAS1	3626	Q86XX4
GLCEFPLRSHLEPTN	GDF5	431	P43026
ACKRPALLHSQFLTP	NFKBIZ	176	Q9BYH8
PFPGIRSSCDRHLLA	MED12L	1151	Q86YW9
FAPVLLLESHCAAAR	MAG	411	P20916
HLPVTRFPCTLACEA	LAMA3	896	Q16787
TPEKLPRAHTCFNRL	NEDD4	1276	P46934
FDSILCEALQHNLPP	NCBP1	256	Q09161
DILALRECFSNHPLG	LETMD1	231	Q6P1Q0
AVDLCVLFPEPARTH	ERVS71-1	71	P61550
PLSCHTRPRALTIGD	ERVS71-1	326	P61550
SIHPLCFALELAPLS	LRRK1	1326	Q38SD2
PLLFPTCQLEELHLS	NLRP11	826	P59045
VFVDCLQPLPSSHLV	GAB3	221	Q8WWW8
EVRFSSHLPQPNSLC	CHUK	251	O15111
FTIPELVHASPCRSS	ERN2	106	Q76MJ5
NCLASLPDDLPHSEA	MED7	166	O43513
LSCTEIPIPLNERHS	JCAD	241	Q9P266
TVHLRPPASCDLEIS	MAPK8IP2	716	Q13387
SILPHSDPERCFSIQ	CDH24	411	Q86UP0
HNLLSDTCPRFILGL	CD1A	176	P06126
ILAVSFAPLIQPCHS	PCMTD2	211	Q9NV79
SPRSQVSLPDTLHCA	KLK15	156	Q9H2R5
IKDSLFAQCHALVPP	MUC2	4696	Q02817
ESHSRPFSLLPSEPC	PEAR1	41	Q5VY43
LCLEPPNTHRVSSFL	FAM47B	331	Q8NA70
LPDPRQFHCISVDSS	GSX1	126	Q9H4S2
LRALPCHSPHQEALS	HERC6	466	Q8IVU3
LSTFPGAEHCLRASP	NSUN5P2	211	Q63ZY6
FPCTLNPHEAESLAL	HEXD	111	Q8WVB3
SCIPEAILNLPHLRS	LRRK2	1186	Q5S007
SSLSDHRPVIELPHC	LRRK2	1671	Q5S007
PALCDPSRLAHRLLV	MFSD1	31	Q9H3U5
PSICSHFNPLSLEEL	SERPINE2	16	P07093
AVCRGSFPHLESLAL	TUBGCP5	1001	Q96RT8
SLCRDVPQSLPHFLV	LDLRAD1	111	Q5T700
ASRCGLQDDFTLHPP	MSLNL	101	Q96KJ4
SLHEAASGLCPRPVL	FANCG	231	O15287
RCSDSDGLAPPQHLI	TP53	181	P04637
DRCLAFHDISPQAPT	HINT1	36	P49773
ICAPDSEHTLLAAPA	GREB1L	1771	Q9C091
APVAHLLASPCTSRP	HIPK3	1131	Q9H422
PRHAVPSATNLCFDV	HPDL	71	Q96IR7
LDHSVALPALTQLPC	CAMK1G	361	Q96NX5
PPGHCLVADRTSEAL	NUTM1	606	Q86Y26
QPLSDDIRAAPISCH	GCKR	546	Q14397
PHQSALRLACETVPT	ITGAD	836	Q13349
ADDRHTCILITPPAN	NID2	836	Q14112
ACDASDPRRAHSPAL	NTN3	66	O00634
SLDCARLPTRNDPHA	FZD9	136	O00144
AFERCHRLSDPSDLP	EXOC5	426	O00471
RPIEETPCHFISSLD	EXOSC10	281	Q01780
NCADPATLTRPVHDA	CDKN2A	71	P42771
HLAPTDPADRLIDTC	HIP1R	711	O75146
DDSAPLVHCVRLLSA	HTT	676	P42858
ASLPPRVAHCRSKDV	FASTKD5	416	Q7L8L6
IRQDTHPPSVIFCLA	GIG44	61	P09565
AASTFLLPPLCHQDD	HEATR5A	706	Q86XA9
RPCPFSIEHILSSLP	GSC2	16	O15499
LPFIHTICPLQEDSS	BFAR	296	Q9NZS9
ATVCHSDLERTPPLL	CABIN1	1766	Q9Y6J0
EHFIPLCLPIRSANI	DOCK10	1106	Q96BY6
PRSRCLHLASSVDPI	LINC01599	131	Q8WXQ3
DRVHSSALFGAICPP	C16orf96	1056	A6NNT2
PCNHVLSLSFPIRRD	GLUD1	111	P00367
LCFAPESHPEVSASL	FRMPD1	1296	Q5SYB0
AAPLSFSLPVHRLLC	C3orf62	51	Q6ZUJ4
RRHPLAACSSAAPFA	C3orf62	66	Q6ZUJ4
LCHPDIIRPITSASA	CYP4F11	101	Q9HBI6
RLHPAPEATVAATCA	LDHD	261	Q86WU2
SDHRLPAPSQCALSR	FAM120C	1046	Q9NX05
HVSAPDLRLCRAPDS	C2CD4D	126	B7Z1M9
TNFLSTLSPEHCRPL	CXXC4	26	Q9H2H0
LEHGARTDICFPPQL	ANKMY1	566	Q9P2S6
ATSHCSLRTVPDIPF	CERS1	266	P27544
HLPNCTARELAPAVS	COPG2	276	Q9UBF2
TCFPVHRAILAARCP	BTBD7	151	Q9P203
DCPLSRLQLFPLTHC	BMF	41	Q96LC9
PLPSEHRSLFLEAAC	ELK3	251	P41970
TIPSSCPRSFAELLH	MAP3K20	226	Q9NYL2
PVTPKALLHFNSICR	FBXO41	806	Q8TF61
PPRLLHTADTCQLEV	GLMP	206	Q8WWB7
HLPEVSLDRASLPCS	HASPIN	206	Q8TF76
SPIKVECAAPSAHAR	ITGA10	861	O75578
AHVLAARADLSCLVP	FAM98C	276	Q17RN3
DSSHLSILIDPRCPD	FIBCD1	86	Q8N539
PHLLPSNECVELFRT	IRF9	311	Q00978
PRCKDSVLPVAHSAA	GSC	16	P56915
CSSSEEDLPLRHPAQ	KIAA1210	866	Q9ULL0
ARLLTRADVECPPAH	CRIPAK	156	Q8N1N5
ARLLTRAHVECPPAH	CRIPAK	351	Q8N1N5
VAPCPLAHLFLSRDQ	CCDC168	231	Q8NDH2
PTLVCASDRDLHSPR	CCDC168	6696	Q8NDH2
LTPRPATEAELLTCH	HDAC6	526	Q9UBN7
FECTTHQPRSPLRDL	GNRH1	61	P01148
PRAFAHCPRLHTLDL	CHADL	271	Q6NUI6
PLCRAAQSERLLTHP	CELSR3	2926	Q9NYQ7
LPPVSQCSELRHSIE	GRK4	36	P32298
LEGSTRTPALPHCLF	FLAD1	31	Q8NFF5
ALISSRPDLLPDFHC	CAND2	361	O75155
APLTPLERIAHENTC	DHX34	1076	Q14147
SPPHRICSFEEAKGL	PPP3CB	471	P16298
LLPIFLAAVPAHRCA	SLC22A7	36	Q9Y694
RFACAICPHRPVLDT	SCNM1	41	Q9BWG6
PEHRCRVPDAANLSS	SLC22A4	46	Q9H015
PEHRCRVPDAANLSS	SLC22A5	46	O76082
PLLTRCAPLFAGTEH	RYR2	2526	Q92736
DTTPSCNSARPLHAL	PPBP	6	P02775
PCNHVLSLSFPIRRD	GLUD2	111	P49448
AALAHPRTLALECPF	NHLRC1	56	Q6VVB1
TSLLLCELPHPAFLL	CSF2RA	6	P15509
PHDAFRASLSCVLPD	IL17RC	676	Q8NAC3
VGACFDRLLHPDAVP	IL17RC	701	Q8NAC3
DLPHGFLTLAALCRE	LIPE	1021	Q05469
ALPTHLITCEHVPRA	PARP10	996	Q53GL7
PPCSATATLHVLLVD	PCDHB8	651	Q9UN66
SRPFRSCDPHDLDIT	MOXD2P	131	A6NHM9
PHFLCDILPVLRLAS	OR10P1	176	Q8NGE3
HIALARLACADPVPS	OR52I2	211	Q8NH67
LIPELRAHFEPTCET	MAP3K15	1131	Q6ZN16
PEVFTLATLRQLPHC	ALOX15B	381	O15296
HLPQSPDTEALSCFL	NUTM2A	346	Q8IVF1
HLPQSPDTEALSCFL	NUTM2B	346	A6NNL0
HLPQSPDTEALSCFL	NUTM2E	346	B1AL46
RRHLPQSPDTEALSC	NUTM2F	221	A1L443
RRHLPQSPDTEALSC	NUTM2G	221	Q5VZR2
FRGPSCTHELLRLPT	NRK	361	Q7Z2Y5
VCDFPLRSHLEPTNH	GDF6	386	Q6KF10
VPSPECESFLEHLQR	RTBDN	81	Q9BSG5
CPALHLPSLSVFSLR	RTP1	11	P59025
VLPRSPADELSHCVE	SYTL2	456	Q9HCH5
DLPPLFLHLTCSVRL	SZT2	1561	Q5T011
CALRPAPRALVLDAH	RNPEPL1	66	Q9HAU8
DPLALCPLVDLFRSH	SCML1	271	Q9UN30
LPSPAHAFRALCTAE	SIGLEC15	176	Q6ZMC9
IDRACPESGHPRVLA	SIDT2	331	Q8NBJ9
PFLRTHCLALQEALG	PNKD	341	Q8N490
PLAHRLAACRVSPAT	FAM83E	331	Q2M2I3
QPAHSCSLRLRPFHL	MTHFD2	16	P13995
DVDLRGSPVHCLLPF	SORCS3	531	Q9UPU3
LQRCHSEVPDFLGAP	RECQL4	191	O94761
CAAAATPVPALALAL	RIPPLY1	6	Q0D2K3
DHVVPLCLPERTFSE	F7	316	P08709
CSPLPVFHSLVELQE	NPY5R	171	Q15761
RPVCLPHSAEPLFSS	OVCH1	681	Q7RTY7
FPAHVSPDCCALIRR	PIM2	251	Q9P1W9
FRCPKRLHSADISPQ	PRDM8	176	Q9NQV8
LCDFPLRSHLEPTNH	GDF7	381	Q7Z4P5
CLSDFIAPLHSGIRD	MTR	1081	Q99707
CVRDLVRSLPAPNHD	ARHGAP27	806	Q6ZUM4
CDPAISPSLHAAAQI	SIPA1L2	236	Q9P2F8
FLHSCETPTRLPLSL	SIMC1	726	Q8NDZ2
DNPNLHSLPFELALC	SHOC2	526	Q9UQ13
LEHVAPQLSPSCLRL	SIPA1	296	Q96FS4
TFSELSHCRGAPELP	SHROOM2	991	Q13796
NTTCHLPRPDAFHIL	SLC5A9	256	Q2M3M2
HHDTTLFRRLLCPDP	SPATA31D4	111	Q6ZUB0
LNKRLTAPPAAFLCH	NHEJ1	61	Q9H9Q4
TAPPAAFLCHLDNLL	NHEJ1	66	Q9H9Q4
IEQSSHPVRSIFCPL	WDR13	401	Q9H1Z4
CGFPAPSESLLREHV	WIZ	421	O95785
SCLARVHAGTLQPPF	INTS5	556	Q6P9B9
PASTCVHLAPRTQLD	KIAA0753	6	Q2KHM9
LLTPSHCDSVALPLD	SPATA31C1	246	P0DKV0
APHSCDTLPTIRQAA	MROH2B	936	Q7Z745
PSDRPLSLAVHCVEH	NUP160	281	Q12769
ACALLLTSVDHDRAP	DLC1	1441	Q96QB1
LQDPHPRVRAAACTT	RANBP6	416	O60518
SLHLVCAVDSNPPAR	SIGLEC12	396	Q96PQ1
LAAPATNHIDPCAVA	MRTFA	601	Q969V6
HFFCDLPPLLSLACS	OR5L2	176	Q8NGL0
LEPHIFPNRSQLCVS	PLA2R1	466	Q13018
LCDLRLSPHFPHTAA	RRP12	516	Q5JTH9
RASAPLACAAAAPLT	SH3RF1	651	Q7Z6J0
ALGRPLPTSHLDLAC	SREBF1	611	P36956
PLPELAALTACTHVQ	ADGRD2	136	Q7Z7M1
ALSPAQLHRARACAP	ADGRD2	281	Q7Z7M1
LSFCLSHPRVQDLPL	AKR1E2	121	Q96JD6
HPAPSQLRCRSLSEF	ACSM1	21	Q08AH1
HQAFLPEGECDTRPL	CNBD2	426	Q96M20
EHLSDLPPFSRCLIG	NCAPG2	1036	Q86XI2
RVCFAQHTPSLPAES	CLCN3	731	P51790
FRPLEIPHRCQDSSS	NEU3	286	Q9UQ49
GHPATCLAVFRELPS	GTF2H4	36	Q92759
HAADPCASRLEPLLA	PITPNM1	731	O00562
ELADLARLHPTSCAP	TNRC18	756	O15417
LTLDPETAHPCLALS	TRIML2	251	Q8N7C3
ADPNHLVDDLLTPCS	VPS4B	371	O75351
HHDTTLFRRLLCPDP	SPATA31D3	111	P0C874
AEALHRQLTACPELP	TBC1D17	571	Q9HA65
GSLFREPIILPCSHN	TRIM67	11	Q6ZTA4
ARPHLQPDSLLDCAA	ZSWIM5	56	Q9P217
LHPDIFLPSEICDRL	ZER1	36	Q7Z7L7
IPFPDHSSELLSCLN	ZBTB7B	11	O15156
RSEPDLRCSPVNSHL	WWC2	261	Q6AWC2
RVPSIDVLCNEFHTP	THOC2	796	Q8NI27
RLPTSHTCFNVLLLP	UBE3A	836	Q05086
LTPRSEPHCLVLSLD	USP16	96	Q9Y5T5
LADTHFVQRCPSVPT	POLR3C	151	Q9BUI4
LLTRPHKAEDFPCGT	TEP1	2041	Q99973
PCEFSESHLSRLAPD	SPEN	3631	Q96T58
HPLARDTPVCLLAVL	RNF112	161	Q9ULX5
LPVACRLPHSSSSEN	SSH2	1206	Q76I76
CESPHLKLLQPFLRT	SSH2	1281	Q76I76
SLLHTAACSLEDRPP	PAPLN	456	O95428
APSVARISSIPHDLC	STIM2	711	Q9P246
DAAPLPLSCHLAAHR	TSPAN32	286	Q96QS1
ALDLPSSHLQCRIPL	WDR97	996	A6NE52
TLKSFCLEPEARLHP	WDR97	1441	A6NE52
ESRCAPRAAASHPLS	ARHGAP28	26	Q9P2N2
PPASIHRELLGVCSD	RASGEF1C	186	Q8N431
CSRVFPSPSSLDQHL	ZNF574	341	Q6ZN55
VPPVLVAFCTHDLES	TMEM104	406	Q8NE00
AFLEPHCLAATLLPS	TREH	561	O43280
SDCQRHFPSLPELSR	ZNF646	11	O15015
LRDAVPATLHLLPCE	RNASEH2C	21	Q8TDP1
ELSFPACNTVHPELL	TTC3	1731	P53804
TPEECGHFRSLLEAP	TMDD1	41	P0DPE3
FLRSQAPPCTAHLRD	TMEM88	71	Q6PEY1
ITALCPLRDVPSHSN	TTC14	161	Q96N46
IRNPVHCFDLASLDP	RRP8	326	O43159
IQPDPLCLHNSSLFA	TLX3	256	O43711
LPADPLCVHNSSLFA	TLX1	291	P31314
CLLAGLESPSHALRA	VWA5B2	226	Q8N398
EAALTPLALDCARAH	ZNHIT2	351	Q9UHR6
TPELVHLDDSPSFCL	WNT9A	286	O14904
TPPCESLVSRHRGAL	ZZEF1	66	O43149
HSTTSCFAPRVPDRL	SEPSECS	221	Q9HD40
TALDLLAEHPQSPCV	TASOR2	276	Q5VWN6
TAAAAAEPLPLRCFQ	ZNF142	276	P52746
VSLPQLRTAHEPCLT	XKR5	646	Q6UX68
SVHAARIPAPQCDIT	VGLL3	266	A8MV65
FLAPACLPGLTHIEA	UBR4	2641	Q5T4S7
PHAPDLSALLCRNSS	UNK	361	Q9C0B0
ALLLLDSCPAHPSSE	TIGD7	291	Q6NT04
INTSCRPATLDTAHP	PVRIG	236	Q6DKI7
LLAVHRCALESPPTS	TREX1	36	Q9NSU2
DCPFTHVSRRIPVLS	ZC3H14	651	Q6PJT7
RLFVDHCVATPTPDQ	ZP3	211	P21754
HLCLPSAFALSIPRS	WNK4	616	Q96J92
PPLSHTRKALCLAAS	nan	146	Q6ZTC4
PCRPLHQLATDSTFS	TRIM28	716	Q13263
SAAVRPVCLPARSHF	TMPRSS6	681	Q8IU80
STLCAHRGLLFVPPN	LRFN4	31	Q6PJG9
FSCEPPLIARHTQRL	LRFN4	276	Q6PJG9
TLPCNALAIPEAHLS	MXRA5	596	Q9NR99
ALSCHEDLLAPISEP	NADSYN1	306	Q6IA69
DVVLHCSFANPLPSV	NECTIN1	46	Q15223