Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	vesicle cargo loading	CTAGE9 MIA3 CTAGE6 CTAGE8 CTAGE15 CTAGE4	4.71e-08	36	116	6	GO:0035459
GeneOntologyBiologicalProcess	endoplasmic reticulum to Golgi vesicle-mediated transport	CTAGE9 MIA3 COPG1 CTAGE6 CTAGE8 CTAGE15 CTAGE4	3.27e-05	159	116	7	GO:0006888
GeneOntologyCellularComponent	endoplasmic reticulum exit site	CTAGE9 MIA3 CTAGE6 CTAGE8 CTAGE15 CTAGE4	1.20e-07	42	117	6	GO:0070971
Domain	TPR-like_helical_dom	P4HA2 TTC14 XAB2 FICD NAA25 RMDN1 COPS4 AIPL1 PDCD11 NUB1	1.19e-06	233	110	10	IPR011990
Domain	TPR-contain_dom	P4HA2 TTC14 XAB2 FICD NAA25 AIPL1 PDCD11	2.99e-05	150	110	7	IPR013026
Domain	-	P4HA2 TTC14 XAB2 FICD NAA25 RMDN1 AIPL1 PDCD11	3.10e-05	207	110	8	1.25.40.10
Domain	DUF1712	CCZ1B CCZ1	3.44e-05	2	110	2	PF08217
Domain	DUF1712_fun	CCZ1B CCZ1	3.44e-05	2	110	2	IPR013176
Domain	Abi_HHR	ABI1 ABI2	1.03e-04	3	110	2	PF07815
Domain	Abl-interactor_HHR_dom	ABI1 ABI2	1.03e-04	3	110	2	IPR012849
Domain	TPR_2	P4HA2 TTC14 XAB2 AIPL1	2.13e-04	50	110	4	PF07719
Domain	TPR_2	P4HA2 TTC14 XAB2 AIPL1	2.13e-04	50	110	4	IPR013105
Domain	TPR_REGION	P4HA2 TTC14 FICD NAA25 RMDN1 AIPL1	4.36e-04	165	110	6	PS50293
Domain	TPR	P4HA2 TTC14 FICD NAA25 RMDN1 AIPL1	4.36e-04	165	110	6	PS50005
Domain	S04_transporter_CS	SLC26A5 SLC26A6	7.08e-04	7	110	2	IPR018045
Domain	TPR_repeat	P4HA2 TTC14 XAB2 FICD AIPL1	1.14e-03	133	110	5	IPR019734
Domain	S1	TTC14 PDCD11	1.50e-03	10	110	2	PS50126
Domain	HAT	XAB2 PDCD11	1.50e-03	10	110	2	SM00386
Domain	SLC26A	SLC26A5 SLC26A6	1.50e-03	10	110	2	PS01130
Domain	HAT	XAB2 PDCD11	1.50e-03	10	110	2	IPR003107
Domain	SH3	MIA3 ABI1 SH3YL1 ABI2 VAV3 FYB2	1.76e-03	216	110	6	SM00326
Domain	STAS	SLC26A5 SLC26A6	1.83e-03	11	110	2	PS50801
Domain	Ephrin_rec_like	EPHB2 SCUBE2	1.83e-03	11	110	2	PF07699
Domain	STAS	SLC26A5 SLC26A6	1.83e-03	11	110	2	PF01740
Domain	SLC26A/SulP_fam	SLC26A5 SLC26A6	1.83e-03	11	110	2	IPR001902
Domain	STAS_dom	SLC26A5 SLC26A6	1.83e-03	11	110	2	IPR002645
Domain	SLC26A/SulP_dom	SLC26A5 SLC26A6	1.83e-03	11	110	2	IPR011547
Domain	-	SLC26A5 SLC26A6	1.83e-03	11	110	2	3.30.750.24
Domain	Sulfate_transp	SLC26A5 SLC26A6	1.83e-03	11	110	2	PF00916
Domain	SH3_domain	MIA3 ABI1 SH3YL1 ABI2 VAV3 FYB2	1.93e-03	220	110	6	IPR001452
Domain	S1	TTC14 PDCD11	2.18e-03	12	110	2	SM00316
Domain	S1_dom	TTC14 PDCD11	2.18e-03	12	110	2	IPR022967
Domain	S1_domain	TTC14 PDCD11	2.18e-03	12	110	2	IPR003029
Domain	Ras_G-nucl-exch_fac_CS	RASGRF2 SOS2	2.99e-03	14	110	2	IPR019804
Domain	OTU	OTUB1 ALG13	3.43e-03	15	110	2	PS50802
Domain	OTU_dom	OTUB1 ALG13	3.43e-03	15	110	2	IPR003323
Domain	ARM-type_fold	COPG1 NCDN KIFAP3 URB1 NF1 CAB39L TAF2	3.94e-03	339	110	7	IPR016024
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	FLNB COPG1 CACNA2D2 DSP OTUB1 UPF1 HNRNPA2B1 PHF2 URB1 NF1 ANAPC1 INTS11 COPS4 PDCD11 TLN2 DLST WDR12 PSME3 TDRD6	3.35e-07	1425	118	19	30948266
Pubmed	Characterization and expression pattern of the novel MIA homolog TANGO.	CTAGE9 MIA3 CTAGE8	3.79e-07	5	118	3	15183315
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	FLNB MIA3 MAP2 CACNA2D2 TSPYL2 TTC14 CHST11 PATL1 HNRNPA2B1 NSRP1 NCDN SH3YL1 PHF2 PKD2 CAB39L KIF5C ARIH1 CATSPERG SOS2	6.50e-07	1489	118	19	28611215
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	KRT78 MAP2 DSP PCDHA1 CHD7 UPF1 PNISR HNRNPA2B1 NSRP1 XAB2 NDUFV2 PHF2 INTS11 DLST CATSPERG ZNF292	8.23e-07	1082	118	16	38697112
Pubmed	hCINAP regulates the differentiation of embryonic stem cells by regulating NEDD4 liquid-liquid phase-separation-mediated YAP1 activation.	OTUB1 TSPYL2 AK6	3.15e-06	9	118	3	36640330
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	CCZ1B COPG1 DSP CHD7 UPF1 HNRNPA2B1 MLKL NF1 CCZ1 ANAPC1 TLN2	4.99e-06	582	118	11	20467437
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	FLNB USP13 DSP TSPYL2 SYNC PNISR XAB2 SH3YL1 NAA25 SCG2 COPS4 TLN2 DLST KIF5C ZNF292 SOS2	7.41e-06	1285	118	16	35914814
Pubmed	Ultrastructural cartilage abnormalities in MIA/CD-RAP-deficient mice.	CTAGE9 MIA3 CTAGE8	1.06e-05	13	118	3	11839810
Pubmed	Functional studies of AIPL1: potential role of AIPL1 in cell cycle exit and/or differentiation of photoreceptors.	AIPL1 NUB1	1.14e-05	2	118	2	15180275
Pubmed	Expression proteomics of UPF1 knockdown in HeLa cells reveals autoregulation of hnRNP A2/B1 mediated by alternative splicing resulting in nonsense-mediated mRNA decay.	UPF1 HNRNPA2B1	1.14e-05	2	118	2	20946641
Pubmed	Abl interactor 1 binds to sos and inhibits epidermal growth factor- and v-Abl-induced activation of extracellular signal-regulated kinases.	ABI1 SOS2	1.14e-05	2	118	2	11003655
Pubmed	Genetic resiliency associated with dominant lethal TPM1 mutation causing atrial septal defect with high heritability.	TPM1 TLN2	1.14e-05	2	118	2	35243414
Pubmed	The expression of the Leber congenital amaurosis protein AIPL1 coincides with rod and cone photoreceptor development.	AIPL1 NUB1	1.14e-05	2	118	2	14638743
Pubmed	The Leber congenital amaurosis protein AIPL1 modulates the nuclear translocation of NUB1 and suppresses inclusion formation by NUB1 fragments.	AIPL1 NUB1	1.14e-05	2	118	2	15347646
Pubmed	Abolished interaction of NUB1 with mutant AIPL1 involved in Leber congenital amaurosis.	AIPL1 NUB1	1.14e-05	2	118	2	15081406
Pubmed	hCINAP is an atypical mammalian nuclear adenylate kinase with an ATPase motif: structural and functional studies.	TSPYL2 AK6	1.14e-05	2	118	2	22038794
Pubmed	Upf1 regulates neurite outgrowth and branching by transcriptional and post-transcriptional modulation of Arc.	UPF1 ARC	1.14e-05	2	118	2	30584064
Pubmed	Role for the Abi/wave protein complex in T cell receptor-mediated proliferation and cytoskeletal remodeling.	ABI1 ABI2	1.14e-05	2	118	2	16401422
Pubmed	The Abl interactor proteins localize to sites of actin polymerization at the tips of lamellipodia and filopodia.	ABI1 ABI2	1.14e-05	2	118	2	11516653
Pubmed	Polycystin-2 associates with tropomyosin-1, an actin microfilament component.	TPM1 PKD2	1.14e-05	2	118	2	12527301
Pubmed	The inherited blindness associated protein AIPL1 interacts with the cell cycle regulator protein NUB1.	AIPL1 NUB1	1.14e-05	2	118	2	12374762
Pubmed	Fibrinogen β chain and FXIII polymorphisms affect fibrin clot properties in acute pulmonary embolism.	F13A1 FGB	1.14e-05	2	118	2	34783023
Pubmed	Constitutive photomorphogenic protein 1 ubiquitinates interleukin-1 receptor accessory protein in human liver cancer.	COP1 IL1RAP	1.14e-05	2	118	2	37700160
Pubmed	Predominant rod photoreceptor degeneration in Leber congenital amaurosis.	AIPL1 NUB1	1.14e-05	2	118	2	16052170
Pubmed	The ATPase hCINAP regulates 18S rRNA processing and is essential for embryogenesis and tumour growth.	TSPYL2 AK6	1.14e-05	2	118	2	27477389
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	FLNB COPG1 DSP CHD7 UPF1 XAB2 URB1 NF1 ANAPC1 PDCD11 WDR12	1.46e-05	653	118	11	22586326
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	EPHB2 FLNB KRT78 COPG1 DSP OTUB1 AK6 UPF1 HNRNPA2B1 XAB2 NAA25 RMDN1 PDCD11 DLST PSME3 ARIH1	1.59e-05	1367	118	16	32687490
Pubmed	Chemical Crosslinking Mass Spectrometry Analysis of Protein Conformations and Supercomplexes in Heart Tissue.	TPM1 DSP UPF1 NDUFV2 FSIP2 RMDN1 FGB DLST	1.83e-05	331	118	8	29199018
Pubmed	Charting the landscape of tandem BRCT domain-mediated protein interactions.	TPM1 FLNB BTBD6 OTUB1 HNRNPA2B1 NSRP1 ANAPC1 ABRAXAS1 PDCD11 NUB1 CATSPERG	1.85e-05	670	118	11	22990118
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	TPM1 FLNB VPS18 KRT78 ABI1 MAP2 DSP UPF1 HNRNPA2B1 NCDN NDUFV2 NF1 TLN2 DLST USP4 KIF5C	2.77e-05	1431	118	16	37142655
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	CACNA2D2 NCDN URB1 KIF5C ZNF292	3.04e-05	105	118	5	9628581
Pubmed	Regulation of cell-cell adhesion by Abi/Diaphanous complexes.	ABI1 ABI2	3.42e-05	3	118	2	19158278
Pubmed	PI3KC3 complex subunit NRBF2 is required for apoptotic cell clearance to restrict intestinal inflammation.	CCZ1B CCZ1	3.42e-05	3	118	2	32160108
Pubmed	Chromatoid Body Protein TDRD6 Supports Long 3' UTR Triggered Nonsense Mediated mRNA Decay.	UPF1 TDRD6	3.42e-05	3	118	2	27149095
Pubmed	Structural insights into the interaction of IL-33 with its receptors.	IL1RAP IL33	3.42e-05	3	118	2	23980170
Pubmed	Associations between variants in IL-33/ST2 signaling pathway genes and coronary heart disease risk.	IL1RAP IL33	3.42e-05	3	118	2	25517029
Pubmed	Preferential binding of a kinesin-1 motor to GTP-tubulin-rich microtubules underlies polarized vesicle transport.	MAP2 KIF5C	3.42e-05	3	118	2	21768290
Pubmed	The Non-catalytic B Subunit of Coagulation Factor XIII Accelerates Fibrin Cross-linking.	F13A1 FGB	3.42e-05	3	118	2	25809477
Pubmed	IL-1 receptor accessory protein and ST2 comprise the IL-33 receptor complex.	IL1RAP IL33	3.42e-05	3	118	2	17675517
Pubmed	In search of a function for the E3B1/Abi2/Argbp1/NESH family (Review).	ABI1 ABI2	3.42e-05	3	118	2	12011975
Pubmed	Associations of the beta-fibrinogen Hae III and factor XIII Val34Leu gene variants with venous thrombosis.	F13A1 FGB	3.42e-05	3	118	2	17582472
Pubmed	Genetic variants of SOS2, MAP2K1 and RASGRF2 in the RAS pathway genes predict survival of HBV-related hepatocellular carcinoma patients.	RASGRF2 SOS2	3.42e-05	3	118	2	37029817
Pubmed	Depletion of hCINAP by RNA interference causes defects in Cajal body formation, histone transcription, and cell viability.	TSPYL2 AK6	3.42e-05	3	118	2	20186459
Pubmed	The IL-1 receptor accessory protein (AcP) is required for IL-33 signaling and soluble AcP enhances the ability of soluble ST2 to inhibit IL-33.	IL1RAP IL33	3.42e-05	3	118	2	18450470
Pubmed	IL-1 receptor accessory protein is essential for IL-33-induced activation of T lymphocytes and mast cells.	IL1RAP IL33	3.42e-05	3	118	2	18003919
Pubmed	A generic approach for the purification of signaling complexes that specifically interact with the carboxyl-terminal domain of G protein-coupled receptors.	MAP2 OTUB1 RGS20 COPS4	3.76e-05	55	118	4	18448421
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	TPM1 KRT78 COPG1 PATL1 UPF1 XAB2 URB1 ANAPC1 BRPF1 TAF2 ZNF292	3.76e-05	724	118	11	36232890
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	FLNB MIS18BP1 COPG1 DSP DOCK10 CHD7 UPF1 HNRNPA2B1 URB1 NF1 INTS11 PDCD11 DLST PSME3 TAF2	5.54e-05	1353	118	15	29467282
Pubmed	Human Cytomegalovirus UL135 Interacts with Host Adaptor Proteins To Regulate Epidermal Growth Factor Receptor and Reactivation from Latency.	ABI1 ABI2 EPCAM	5.59e-05	22	118	3	30089695
Pubmed	Abl interactor 1 (Abi-1) wave-binding and SNARE domains regulate its nucleocytoplasmic shuttling, lamellipodium localization, and wave-1 levels.	ABI1 ABI2	6.82e-05	4	118	2	15143189
Pubmed	Localization and phosphorylation of Abl-interactor proteins, Abi-1 and Abi-2, in the developing nervous system.	ABI1 ABI2	6.82e-05	4	118	2	10995551
Pubmed	Mea6 controls VLDL transport through the coordinated regulation of COPII assembly.	CTAGE9 CTAGE8	6.82e-05	4	118	2	27311593
Pubmed	Structural interaction and functional regulation of polycystin-2 by filamin.	FLNB PKD2	6.82e-05	4	118	2	22802962
Pubmed	Deletion of Mea6 in Cerebellar Granule Cells Impairs Synaptic Development and Motor Performance.	CTAGE9 CTAGE8	6.82e-05	4	118	2	33718348
Pubmed	Specific expression and regulation of the new melanoma inhibitory activity-related gene MIA2 in hepatocytes.	CTAGE9 CTAGE8	6.82e-05	4	118	2	12586826
Pubmed	Developmental expression of IL-33 in the mouse brain.	MAP2 IL33	6.82e-05	4	118	2	24076135
Pubmed	The use of knockout mice reveals a synergistic role of the Vav1 and Rasgrf2 gene deficiencies in lymphomagenesis and metastasis.	RASGRF2 VAV3	6.82e-05	4	118	2	20011522
Pubmed	MEA6 Deficiency Impairs Cerebellar Development and Motor Performance by Tethering Protein Trafficking.	CTAGE9 CTAGE8	6.82e-05	4	118	2	31244610
Pubmed	Aspects of the neuroendocrine cerebellum: expression of secretogranin II, chromogranin A and chromogranin B in mouse cerebellar unipolar brush cells.	MAP2 SCG2	6.82e-05	4	118	2	19217926
Pubmed	Reduced cholesterol and triglycerides in mice with a mutation in Mia2, a liver protein that localizes to ER exit sites.	CTAGE9 CTAGE8	6.82e-05	4	118	2	21807889
Pubmed	The effect of four hemostatic gene polymorphisms on the outcome of septic critically ill patients.	F13A1 FGB	6.82e-05	4	118	2	20051843
Pubmed	Identification of two evolutionarily conserved genes regulating processing of engulfed apoptotic cells.	CCZ1B CCZ1	6.82e-05	4	118	2	20305638
Pubmed	Polymorphism of genes related to cardiovascular disease in patients with rheumatoid arthritis.	F13A1 FGB	6.82e-05	4	118	2	18173921
Pubmed	Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.	FLNB P4HA2 ABI1 COPG1 OTUB1 UPF1 MLKL COPS4 DLST PSME3	9.34e-05	665	118	10	30457570
Pubmed	Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.	DSP CD109 HNRNPA2B1 ERICH6B PDCD11 WDR12	9.40e-05	214	118	6	22199357
Pubmed	Structural and functional consequences of NEDD8 phosphorylation.	USP13 OTUB1 USP4 NUB1	9.71e-05	70	118	4	34642328
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	OTUB1 AK6 CHD7 UPF1 HNRNPA2B1 PHF2 MLKL CCZ1 MED22 COPS4 SMS PSME3 ZNF292	9.82e-05	1103	118	13	34189442
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	FLNB MIA3 COPG1 DSP UPF1 HNRNPA2B1 BRPF1 SMS PSME3 SPAG17 ALG13	9.88e-05	807	118	11	30575818
Pubmed	Large-scale analysis of the human ubiquitin-related proteome.	HNRNPA2B1 NCDN ABRAXAS1 COPS4 DLST USP4 PSME3	1.00e-04	313	118	7	16196087
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	TPM1 FLNB DSP CTAGE6 PNISR HNRNPA2B1 NDUFV2 CTAGE8 CTAGE15 UGGT2 DLST KIF5C CTAGE4 SPAG17 ZNF292	1.13e-04	1442	118	15	35575683
Pubmed	Epistatic and pleiotropic effects of polymorphisms in the fibrinogen and coagulation factor XIII genes on plasma fibrinogen concentration, fibrin gel structure and risk of myocardial infarction.	F13A1 FGB	1.13e-04	5	118	2	16525568
Pubmed	Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.	CTAGE9 CTAGE8	1.13e-04	5	118	2	19131326
Pubmed	The length of peptide substrates has a marked effect on hydroxylation by the hypoxia-inducible factor prolyl 4-hydroxylases.	P4HA2 EPAS1	1.13e-04	5	118	2	16885164
Pubmed	cTAGE: a cutaneous T cell lymphoma associated antigen family with tumor-specific splicing.	CTAGE9 CTAGE4	1.13e-04	5	118	2	12839582
Pubmed	Vav family GEFs link activated Ephs to endocytosis and axon guidance.	EPHB2 VAV3	1.13e-04	5	118	2	15848800
Pubmed	The Leber congenital amaurosis protein AIPL1 functions as part of a chaperone heterocomplex.	AIPL1 NUB1	1.13e-04	5	118	2	18408180
Pubmed	ABI2-deficient mice exhibit defective cell migration, aberrant dendritic spine morphogenesis, and deficits in learning and memory.	ABI1 ABI2	1.13e-04	5	118	2	15572692
Pubmed	The inherited blindness protein AIPL1 regulates the ubiquitin-like FAT10 pathway.	AIPL1 NUB1	1.13e-04	5	118	2	22347407
Pubmed	Abl-interactor-1 (Abi1) has a role in cardiovascular and placental development and is a binding partner of the alpha4 integrin.	ABI1 ABI2	1.13e-04	5	118	2	21173240
Pubmed	Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis.	CTAGE9 CTAGE8	1.13e-04	5	118	2	18630941
Pubmed	Mea6/cTAGE5 cooperates with TRAPPC12 to regulate PTN secretion and white matter development.	CTAGE9 CTAGE8	1.13e-04	5	118	2	38439956
Pubmed	A tissue-specific atlas of mouse protein phosphorylation and expression.	CTAGE9 CTAGE8	1.13e-04	5	118	2	21183079
Pubmed	CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation.	COP1 TLE2 WDR12	1.17e-04	28	118	3	17041588
Pubmed	The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity.	ABI1 MAP2 ARC	1.30e-04	29	118	3	19208628
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	TPM1 FLNB P4HA2 MIA3 COPG1 DSP OTUB1 CD109 XAB2 COPS4 PDCD11 UGGT2 WDR12 ARIH1	1.32e-04	1297	118	14	33545068
Pubmed	Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.	USP13 VPS18 OTUB1 NF1 USP4	1.50e-04	147	118	5	29576527
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	TPM1 FLNB TSPYL2 UPF1 HNRNPA2B1 XAB2 URB1 BRPF1 PDCD11 DLST WDR12	1.51e-04	847	118	11	35850772
Pubmed	USP45 and Spindly are part of the same complex implicated in cell migration.	FLNB COPG1 OTUB1 UPF1 USP4 PSME3	1.57e-04	235	118	6	30258100
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	MIA3 MAP2 OTUB1 DNAJB7 UPF1 HNRNPA2B1 NSRP1 NCDN NDUFV2 URB1 COPS4 PDCD11 UGGT2 DLST WDR12	1.58e-04	1487	118	15	33957083
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	FLNB P4HA2 USP13 COPG1 OTUB1 ABRAXAS1 COPS4 UGGT2 DLST USP4 PSME3 ARIH1	1.64e-04	1005	118	12	19615732
Pubmed	Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy.	CCZ1B VPS18 XAB2 NF1 CCZ1 DLST WDR12 TAF2	1.66e-04	454	118	8	33226137
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	EPHB2 VPS18 COP1 CCDC178 MUC12 PATL1 UPF1 HNRNPA2B1 XAB2 NF1 ANAPC1 SMS SLC26A6 ZNF292	1.67e-04	1327	118	14	32694731
Pubmed	LukS-PV inhibits hepatocellular carcinoma cells migration by downregulating HDAC6 expression.	TPM1 FLNB COPG1 DSP CD109 UPF1 HNRNPA2B1 DLST TDRD6	1.68e-04	580	118	9	35676659
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	TPM1 ABI1 CHD7 PNISR XAB2 NDUFV2 LSM3 PHF2 URB1 ABI2 ANAPC1 INTS11 PDCD11 WDR12 TAF2	1.69e-04	1497	118	15	31527615
Pubmed	Reconstitution of ST2 (IL-1R4) specific for IL-33 activity; no suppression by IL-1Ra though a common chain IL-1R3 (IL-1RAcP) shared with IL-1.	IL1RAP IL33	1.70e-04	6	118	2	27031441
Pubmed	Dispersion of chromogranin/secretogranin secretory protein family loci in mammalian genomes.	MAP2 SCG2	1.70e-04	6	118	2	8617499
Pubmed	Haemostatic genetic variants, ABO blood group and bleeding risk during oral anticoagulant treatment after cerebral ischaemia of arterial origin.	F13A1 FGB	1.70e-04	6	118	2	17994314
Pubmed	Hypoxia-inducible factor-1 (HIF-1) but not HIF-2 is essential for hypoxic induction of collagen prolyl 4-hydroxylases in primary newborn mouse epiphyseal growth plate chondrocytes.	P4HA2 EPAS1	1.70e-04	6	118	2	22930750
Pubmed	VHL genetic alteration in CCRCC does not determine de-regulation of HIF, CAIX, hnRNP A2/B1 and osteopontin.	HNRNPA2B1 EPAS1	1.70e-04	6	118	2	20978319
Pubmed	Sarm1, a negative regulator of innate immunity, interacts with syndecan-2 and regulates neuronal morphology.	MAP2 NF1	1.70e-04	6	118	2	21555464
Interaction	CTAGE1 interactions	MIA3 CTAGE6 CTAGE8 CTAGE15 CTAGE4	1.49e-09	10	117	5	int:CTAGE1
Cytoband	7q35	CTAGE6 CTAGE8 CTAGE15 CTAGE4	1.28e-05	55	118	4	7q35
Cytoband	Ensembl 112 genes in cytogenetic band chr7q35	CTAGE6 CTAGE8 CTAGE15 CTAGE4	2.64e-05	66	118	4	chr7q35
Cytoband	3p21.3	CACNA2D2 USP4 SLC26A6	4.84e-04	59	118	3	3p21.3
GeneFamily	CTAGE family	CTAGE9 CTAGE6 CTAGE8 CTAGE15 CTAGE4	2.91e-09	15	74	5	907
ToppCell	PSB\|World / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TPM1 P4HA2 ERICH3 DSP DNAI3 SPAG17 EPCAM FYB2 SLC27A2	3.05e-09	198	118	9	4e6b0d1abc55d7a0d89bd7ecf0f13dc5bed66626
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-mature_enterocytic\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DSP SI MUC12 VAV3 EPCAM DNASE1 SLC27A2	9.70e-07	197	118	7	a6a27e5809ee2c9b56c7e06c35e4f140f9fa13ad
ToppCell	(01)_IL1RL1+-(2)_GFP_FOXI1\|(01)_IL1RL1+ / shred by cell type by condition	TPM1 MIS18BP1 CHD7 NSRP1 ANKRD18B NDUFV2 ZNF292	1.04e-06	199	118	7	a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Intermediate\|2m / Sample Type, Dataset, Time_group, and Cell type.	MAP2 PNISR NF1 ABI2 SCG2 KIF5C ZNF292	1.07e-06	200	118	7	2a635694844ddabcd98462c5636a6f41a3f08a46
ToppCell	facs-Marrow-KLS-3m-Hematologic-Unknown_Progenitor\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P4HA2 ERICH3 UGGT2 KCNMB4 EPCAM PRLR	5.98e-06	169	118	6	b798b91567d2f49082e2d8a337169f241c8d2080
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-neuro-epithelial-N_cells_(NTS+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ERICH3 MAP2 DSP SCG2 FGB FYB2	7.30e-06	175	118	6	97a58bc6ed2e8e359283d4214172c990c6e3755e
ToppCell	5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DSP FSIP2 SCUBE2 SCG2 EPCAM PRLR	8.85e-06	181	118	6	40df0afcb6848202da54670e84f22d7c3a515d01
ToppCell	5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DSP FSIP2 SCUBE2 SCG2 EPCAM PRLR	8.85e-06	181	118	6	2b53a65ca5616a7b9f64232c3e0b7212d1e2f063
ToppCell	5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DSP FSIP2 SCUBE2 SCG2 EPCAM PRLR	8.85e-06	181	118	6	6aef84616e8d2faf54b7e9e6cd02f33c3066dabc
ToppCell	5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DSP FSIP2 SCUBE2 SCG2 EPCAM PRLR	8.85e-06	181	118	6	40d3829ae4aaf81e8616c3499ff8933137fc1cc4
ToppCell	COVID-19-Endothelial_cells-Systemic_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	FLNB RASGRF2 KLHL3 KCNMB4 IL33 EPAS1	1.00e-05	185	118	6	f5e14181f45c37d13ee9e017a4c8bc248c353676
ToppCell	Control-Endothelial_cells-Arterial_endothelial_cells\|Control / group, cell type (main and fine annotations)	FLNB RASGRF2 ARC KCNMB4 IL33 EPAS1	1.07e-05	187	118	6	81affaab3fe3e1daea45ada6445e906ddd33950e
ToppCell	COVID-19-lung-Vein_EC\|lung / Disease (COVID-19 only), tissue and cell type	FLNB RASGRF2 CD109 KLHL3 IL33 EPAS1	1.10e-05	188	118	6	d582b76fc2faac526c9bf97503041129e1a6a211
ToppCell	LV-14._Fibroblast_III\|World / Chamber and Cluster_Paper	EPHB2 TSPYL2 UGGT2 KIF5C ARIH1 ALG13	1.13e-05	189	118	6	3922135d1f6fc768d71ba3b465585fead6ea68a8
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-AEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FLNB RASGRF2 ARC KCNMB4 IL33 EPAS1	1.20e-05	191	118	6	50601ef0a5a8f2c2120922989e08e85bf2d9b4ab
ToppCell	droplet-Pancreas-Endocrine\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COPG1 TTC14 PNISR HNRNPA2B1 SCG2 PRLR	1.24e-05	192	118	6	0dfd1e9896c34aee0f842f8de5d0e3af62a15f68
ToppCell	IPF-Endothelial-VE_Arterial\|IPF / Disease state, Lineage and Cell class	RASGRF2 MAP2 ARC KCNMB4 IL33 EPAS1	1.27e-05	193	118	6	bf83b1fe9d38408f30eee4eb634341c04ef82791
ToppCell	RA-08._Macrophage\|RA / Chamber and Cluster_Paper	DOCK10 CHST11 F13A1 MLKL VAV3 IL1RAP	1.31e-05	194	118	6	ac26e5c71d5069622de72fa25a9c920887ac2c19
ToppCell	Control_saline-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control_saline / Treatment groups by lineage, cell group, cell type	TPM1 DSP SLC26A5 SH3YL1 ARC EPCAM	1.47e-05	198	118	6	85f424cd9bb3117c9e322031024aabb87696ce47
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-2_Progenitor-Progenitor_AT1-AT2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	TPM1 DSP SLC26A5 NDUFV2 SH3YL1 EPCAM	1.47e-05	198	118	6	8d9858dcb21f20d0c040b22a2cae543eaebd54bc
ToppCell	Control_saline-Epithelial_alveolar-AT_1\|Control_saline / Treatment groups by lineage, cell group, cell type	TPM1 DSP SLC26A5 SH3YL1 ARC EPCAM	1.47e-05	198	118	6	9b161285df7a4e51618f3517cfc5b8221ba55786
ToppCell	LPS_only-Epithelial_airway-airway_epithelial-Airway-Club\|LPS_only / Treatment groups by lineage, cell group, cell type	KRT78 DSP SH3YL1 KIF5C SPAG17 EPCAM	1.52e-05	199	118	6	165ac94b2d56072ad43358b5127d77555221e2d8
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	TPM1 DSP SLC26A5 SH3YL1 ARC EPCAM	1.52e-05	199	118	6	1c70e7d6bd25980e1b92aa1cac3f3c95d9651b4b
ToppCell	distal-Endothelial-Artery-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TPM1 FLNB ARC KCNMB4 IL33 EPAS1	1.52e-05	199	118	6	3788f3218356aaaa10684e48d63757037f8a3a3c
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ERICH3 CACNA2D2 DSP SH3YL1 SPAG17 EPCAM	1.56e-05	200	118	6	21d9cf3cd3696ad6b745c7c036798f04b6ce5160
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1-2_Progenitor-AT1_Progenitor\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	TPM1 DSP NDUFV2 SH3YL1 ARC EPCAM	1.56e-05	200	118	6	3b170736fce1fccea9ec0b5a9075c70e5bc09d8e
ToppCell	Lung_Parenchyma-Severe-Epithelial\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	ERICH3 CACNA2D2 DSP SH3YL1 SPAG17 EPCAM	1.56e-05	200	118	6	33658d5d09e2eaff60f4dd88837d4252328eab63
ToppCell	Parenchyma_COVID-19-Epithelial-TX\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	ERICH3 CACNA2D2 DSP SH3YL1 SPAG17 EPCAM	1.56e-05	200	118	6	d5426cd318a8f90c0bd8f9804351ab230fafc995
ToppCell	LPS_only-Epithelial_alveolar-AT_1\|LPS_only / Treatment groups by lineage, cell group, cell type	TPM1 DSP SLC26A5 SH3YL1 ARC EPCAM	1.56e-05	200	118	6	9a6ae40f3e17cd44ee5fd73260713b920aa2ea15
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	CACNA2D2 CD109 CCZ1 ARC EPAS1 SLC26A6	1.56e-05	200	118	6	be83f442179ba4217d12f0458059586ff3130991
ToppCell	ASK440-Epithelial\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	ERICH3 CACNA2D2 DSP SH3YL1 SPAG17 EPCAM	1.56e-05	200	118	6	cb617e2a0ca82b470b473b8d5906bc8879c85718
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Pi16_(Pi16)\|Thalamus / BrainAtlas - Mouse McCarroll V32	MIS18BP1 DSP AK6 MLKL ANGEL2	3.83e-05	142	118	5	58bfff3284ae21150e4619511bd58622c16c5dde
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Pi16_(Pi16)--\|Thalamus / BrainAtlas - Mouse McCarroll V32	MIS18BP1 DSP AK6 MLKL ANGEL2	3.83e-05	142	118	5	5fd737c1fee9d97aee8955f1bf378ead3fce138d
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Pi16_(Pi16)-\|Thalamus / BrainAtlas - Mouse McCarroll V32	MIS18BP1 DSP AK6 MLKL ANGEL2	3.83e-05	142	118	5	16f9945e835c3506b12d904778560d065a50f059
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA2D2 MUC12 KLHL3 PRLR FYB2	4.24e-05	145	118	5	9964d6d3769be2f35d86268fe044cecd1d5a1616
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW08-Neuronal\|GW08 / Sample Type, Dataset, Time_group, and Cell type.	MAP2 NCDN KIFAP3 KIF5C	6.10e-05	80	118	4	5c39136f5f855efbf61e1f5348ea97ea2130b241
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	RASGRF2 KLHL3 KCNMB4 IL33 EPAS1	6.18e-05	157	118	5	275a4c6fef1fff8da2bdc48e3924ad05c5e5cfc8
ToppCell	facs-MAT-Fat-24m-Epithelial-nan\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSP SCG2 FGB EPCAM SLC27A2	6.18e-05	157	118	5	30814ff90cead688ef64dac4cf4a6d63756d8944
ToppCell	facs-MAT-Fat-24m-Epithelial\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSP SCG2 FGB EPCAM SLC27A2	6.18e-05	157	118	5	a47d102570e82d34ea1a8756f82636e7ab27c07f
ToppCell	facs-MAT-Fat-24m-Epithelial-epithelial_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSP SCG2 FGB EPCAM SLC27A2	6.18e-05	157	118	5	7c20f225b2db8b340f4fec050ff29e666b860f04
ToppCell	Ciliated_cells-B-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	ERICH3 DNAI3 ANKRD18B SPAG17 SLC27A2	7.60e-05	164	118	5	0e9961acbb1d6c0089e6805ba6756736fa4d8bed
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FSIP2 SCUBE2 CTAGE8 EPCAM SLC27A2	8.05e-05	166	118	5	60060b03f2abfa3cc08107ab5a9f578e60e4ae16
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FSIP2 SCUBE2 CTAGE8 EPCAM SLC27A2	8.05e-05	166	118	5	ec9161d388db5a257b8d125c14f9dd911d5d5d4a
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FSIP2 SCUBE2 CTAGE8 EPCAM SLC27A2	8.05e-05	166	118	5	4586d6725403f879fc96f67be579022587ce1906
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DSP PNISR FICD BRPF1 TDRD6	8.05e-05	166	118	5	c11dcf9705b85ac3da6ae86358f5ffd64ae8327e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RASGRF2 MAP2 CD109 DNAJB7 EPAS1	8.05e-05	166	118	5	8e5f2afbeffae5e77fcb29e8fe9f5aa49779b619
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ABI1 NCDN KLHL3 ABI2 ARC	8.51e-05	168	118	5	6db453cbbbaf4144a86fadcfa5805d33396713b5
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DSP SCG2 FGB TDRD6 CTAGE4	9.00e-05	170	118	5	985c2d5962100fab0d95bee39f382ccbe799331e
ToppCell	Club-club-15\|World / Class top	MIS18BP1 LSM3 MLKL AIPL1 USP4	1.03e-04	175	118	5	ca9d012f520f697c7450ec6958a015e20538a6a8
ToppCell	NS-moderate-d_0-4-Epithelial-Ionocyte\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RASGRF2 CACNA2D2 SCUBE2 SCG2 PRLR	1.03e-04	175	118	5	a1e0a15c69211d6db2edeb101476f0f6e08b90c8
ToppCell	COPD-Epithelial-Aberrant_Basaloid\|COPD / Disease state, Lineage and Cell class	TPM1 EPHB2 DSP TLE2 EPCAM	1.06e-04	176	118	5	11d867bcb4f2471b4e13a5f7dc1c24286197f26d
ToppCell	human_hepatoblastoma-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	ERICH3 CHST11 DNAI3 KCNMB4 VAV3	1.15e-04	179	118	5	14fc8ccb6b215063d747643f47d780d2b237eb67
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA2D2 CHD7 CCZ1 BRPF1 PDZD4	1.18e-04	180	118	5	c72f15763ba707189e29c85db533557f01c7fdb1
ToppCell	NS-critical-d_0-4-Epithelial-Ionocyte\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	KLHL3 SCUBE2 SCG2 EPCAM PRLR	1.21e-04	181	118	5	cfc3ed541d93158ce26641ea30b7573d93600a11
ToppCell	facs-Marrow-T-cells-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNB DOCK10 F13A1 FYB2 PDZD4	1.21e-04	181	118	5	7286700396676fdc41d9723979b8b408177aceb9
ToppCell	AT1-AT2_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	CTAGE9 FLNB MAP2 CACNA2D2 DSP	1.27e-04	183	118	5	6821dca076318115d360ff426eb1218cfe104063
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNB VPS18 KCNMB4 NUB1 SMC1B	1.34e-04	185	118	5	87151ab95530e70d61328b336518df58db584acb
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FLNB RASGRF2 KCNMB4 IL33 EPAS1	1.34e-04	185	118	5	a7ae76058b2082020cadec49d63b9f4e24d21734
ToppCell	Control-Endothelial-Endothelial-Vein\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLNB RASGRF2 TLN2 IL33 PRLR	1.37e-04	186	118	5	92092f11ecce22c14f244e42c499af0822977e6f
ToppCell	Adult-Endothelial-endothelial_cell_of_artery\|Adult / Lineage, Cell type, age group and donor	RASGRF2 ARC KCNMB4 IL33 EPAS1	1.37e-04	186	118	5	2d1c4ea2e401db89971582ee54618a8b0c81b8ac
ToppCell	IPF-Epithelial-Aberrant_Basaloid\|IPF / Disease state, Lineage and Cell class	TPM1 EPHB2 MAP2 DSP EPCAM	1.41e-04	187	118	5	19d6a404fc3651d98a93e3848e372df51a239c57
ToppCell	Ciliated_cells-B-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	ERICH3 DNAI3 ANKRD18B SPAG17 FYB2	1.41e-04	187	118	5	6fa38dbccca36bc7a4fef46de74c6688f599f421
ToppCell	15-Airway-Epithelial-Neuroendocrine\|Airway / Age, Tissue, Lineage and Cell class	CTAGE9 DSP SCG2 KIF5C EPCAM	1.41e-04	187	118	5	a7d2f30fe0f19e63d44603ece9890acd11b45e52
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	TSPYL2 DOCK10 HNRNPA2B1 NF1 ARIH1	1.44e-04	188	118	5	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	COVID-19-lung-Artery_EC\|lung / Disease (COVID-19 only), tissue and cell type	RASGRF2 ARC KCNMB4 IL33 EPAS1	1.44e-04	188	118	5	eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	TPM1 FLNB MAP2 DOCK10 PKD2	1.44e-04	188	118	5	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RASGRF2 MAP2 CD109 IL33 EPAS1	1.44e-04	188	118	5	c2c51c6526defe2600302901159b8abbb58d7595
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.4\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ERICH3 SCUBE2 SCG2 SPAG17 FYB2	1.48e-04	189	118	5	cd4746ea6ae48a7dd14a2960d38d9445a738cf2c
ToppCell	Endothelial-endothelial_cell_of_artery\|World / Lineage, Cell type, age group and donor	RASGRF2 ARC KCNMB4 IL33 EPAS1	1.48e-04	189	118	5	fdd89c71113ac99b7c800c6def8888e512ff1128
ToppCell	IPF-Epithelial-Aberrant_Basaloid\|World / Disease state, Lineage and Cell class	TPM1 EPHB2 MAP2 DSP EPCAM	1.48e-04	189	118	5	8030a353473da34ae92429f2d822171a2e94248f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RASGRF2 MAP2 CD109 IL33 EPAS1	1.48e-04	189	118	5	12b6f1c3bf526b90e112374bf937701f645c5780
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	TPM1 FLNB MAP2 DOCK10 PKD2	1.48e-04	189	118	5	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4-POLYDENDROCYTE_(Rostral-�migratory_stream-�(RMS)_(Tuba1c))\|Striatum / BrainAtlas - Mouse McCarroll V32	MIS18BP1 SLC26A5 DNAJB7 AIPL1	1.51e-04	101	118	4	0b32e6071f05dbe808e51e18c3a3f8221f438f83
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAP2 CD109 KCNMB4 IL33 EPAS1	1.52e-04	190	118	5	bf9bc57a605c7e3979bc4f7260e6fb92c3eb8690
ToppCell	COVID-19-lung-Artery_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RASGRF2 ARC KCNMB4 IL33 EPAS1	1.52e-04	190	118	5	07b675befcd1d0a9c90cb17b5d22323468325d51
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-intermediate_neuroendocrine\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	FLNB ERICH3 DSP SCG2 KIF5C	1.52e-04	190	118	5	5f1863bce9400b7c932f0e4d0e012ec4e8d7e555
ToppCell	COVID-19-kidney-AQP1+SLC14A1+EC\|kidney / Disease (COVID-19 only), tissue and cell type	RASGRF2 MAP2 CD109 IL33 EPAS1	1.52e-04	190	118	5	1519f34d31fe0817184c5865a0bc9f0cb479b1a4
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTC14 PNISR HNRNPA2B1 SCG2 PRLR	1.55e-04	191	118	5	fd01a206763dfb6d52cca67123571936b4a8e1a0
ToppCell	droplet-Mammary_Gland-nan-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSP KIF5C EPCAM IL33 PRLR	1.55e-04	191	118	5	b94e66ac71e73f46b0323d424e7b8b906751d584
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RASGRF2 MAP2 CD109 IL33 EPAS1	1.55e-04	191	118	5	b2c86cde341fe350143658c8a8a4a9edbce3f19b
ToppCell	LAM-Epithelial-AirwayEpi\|LAM / Condition, Lineage and Cell class	ERICH3 DNAI3 SPAG17 FYB2 SLC27A2	1.59e-04	192	118	5	7404fc65be3b7bd09447725b43fa31819004dfee
ToppCell	IPF-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	MAP2 ARC KCNMB4 IL33 EPAS1	1.59e-04	192	118	5	e911e286da26202853f9650ba3cdefe5a5c9b585
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MIA3 TTC14 PNISR SCG2 PRLR	1.59e-04	192	118	5	1304e69c92cef3bd8c82e3c035a7562f5440139a
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CTAGE9 RASGRF2 CD109 CCDC178 EPAS1	1.59e-04	192	118	5	3259cb89d6bcf0a3c6ff1f64d85e8a1f54124e91
ToppCell	droplet-Pancreas-Endocrine-18m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTC14 PNISR HNRNPA2B1 SCG2 PRLR	1.59e-04	192	118	5	4510aa262da8dcf7c944b3907a51aba5a9397a4e
ToppCell	11.5-Airway-Epithelial-Bud_tip_progenitor\|Airway / Age, Tissue, Lineage and Cell class	DSP SH3YL1 KIF5C EPCAM SLC27A2	1.63e-04	193	118	5	f0a07bb221a497a9f7cc706045d5205269be4515
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ERICH3 DNAI3 ANKRD18B SPAG17 FYB2	1.63e-04	193	118	5	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	RA-08._Macrophage\|World / Chamber and Cluster_Paper	DOCK10 F13A1 MLKL VAV3 IL1RAP	1.63e-04	193	118	5	5fd22db1825d105709fcc0aa4955c99a117e3c82
ToppCell	IPF-Endothelial-VE_Arterial\|World / Disease state, Lineage and Cell class	RASGRF2 ARC KCNMB4 IL33 EPAS1	1.63e-04	193	118	5	70a9aadda83a97e06e9bc2d1327ce60dd3c58767
ToppCell	5'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAP2 CD109 CCDC178 AIPL1 EPAS1	1.63e-04	193	118	5	c0973a2c97deb7176c2f617c8760a55f7edc9839
ToppCell	10x3'2.3-week_14-16-Lymphocytic_B-B_lineage-pro_B_progenitor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	ABI1 PNISR HNRNPA2B1 NUB1 ZNF292	1.67e-04	194	118	5	f64da5f62e29253d60b9546edf734ba5c17daae1
ToppCell	LV-14._Fibroblast_III\|LV / Chamber and Cluster_Paper	EPHB2 TSPYL2 UGGT2 KIF5C ALG13	1.67e-04	194	118	5	927c26aea0147f7a4b8fb3f192de4de263f1b978
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RASGRF2 CD109 MLKL ARC IL33	1.67e-04	194	118	5	a429d22c8c9d0fd3bfa9f877a6364cecad68db30
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAP2 CHD7 SCG2 ARC KIF5C	1.67e-04	194	118	5	5bd0f739aa75f387cca7c3b2686493ee2d1ee968
ToppCell	CTRL-Myeloid-Monocyte_Macrophage\|CTRL / Disease state, Lineage and Cell class	OLFML2B CD109 CHST11 F13A1 PRLR	1.67e-04	194	118	5	927480f56cccd3940b689f3c40ee132fe3e63745
ToppCell	5'-Adult-SmallIntestine-Epithelial-Tuft-related\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TPM1 DSP SI EPCAM FYB2	1.71e-04	195	118	5	23ab7e2a419377c05bab0e92a2457afbcd3d9e07
ToppCell	3'-Distal_airway-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TPM1 ARC KCNMB4 IL33 EPAS1	1.71e-04	195	118	5	83da75d210ae9c2a94018d70cb9e833b37004c4e
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ERICH3 DNAI3 SPAG17 FYB2 SLC27A2	1.71e-04	195	118	5	9651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EPHB2 DSP SCUBE2 TLE2 EPCAM	1.71e-04	195	118	5	b67d4f34cae729c18275486d3b20c9dd7d5cbe79
ToppCell	11.5-Distal-Epithelial-Bud_tip_progenitor\|Distal / Age, Tissue, Lineage and Cell class	DSP SH3YL1 KIF5C EPCAM SLC27A2	1.75e-04	196	118	5	42eae265e2f2082983d8c2607c7f6a53a526d124
Disease	intracranial volume measurement	TPM1 PDCD11 TLN2	2.47e-04	33	109	3	EFO_0004886
Disease	hoarding disorder	TPM1 TLN2 FYB2	3.20e-04	36	109	3	EFO_0803361
Disease	insulin sensitivity measurement, response to polyunsaturated fatty acid supplementation	TPM1 TLN2	7.28e-04	11	109	2	EFO_0004471, EFO_0009131
Disease	phenylalanine measurement	VPS18 CHST11 FGB	1.12e-03	55	109	3	EFO_0005001
Disease	Hermansky-Pudlak syndrome (implicated_via_orthology)	CCZ1B CCZ1	1.20e-03	14	109	2	DOID:3753 (implicated_via_orthology)
Disease	level of C-X-C motif chemokine 3 in blood serum	TNFAIP8L2 OLFML2B	1.38e-03	15	109	2	OBA_2041208
Disease	neutrophil count	FLNB OLFML2B PCDHA1 CHD7 LSM3 KIFAP3 MED22 FGB TLN2 VAV3 DNASE1 MTRF1L ZNF292	1.77e-03	1382	109	13	EFO_0004833
Disease	Hereditary Paraganglioma-Pheochromocytoma Syndrome	NF1 EPAS1	3.25e-03	23	109	2	C1708353
Disease	body fat percentage, coronary artery disease	MIA3 WDR12	3.54e-03	24	109	2	EFO_0001645, EFO_0007800
Disease	Noonan Syndrome	NF1 SOS2	3.54e-03	24	109	2	C0028326

Protein segments in the cluster

Peptide	Gene	Start	Entry
DDVEVVYTIDIQKYI	ABRAXAS1	51	Q6UWZ7
YDTIFEDYEKLLQSE	CAB39L	206	Q9H9S4
KVYEYDTVIQDAVDI	COP1	446	Q8NHY2
TLDSLKDYSEDEIYR	CATSPERG	956	Q6ZRH7
EYLEKAGYLEEEEYI	ERICH6B	96	Q5W0A0
ENTLKYEYEEDFEVD	ERICH3	491	Q5RHP9
EDYYTSLDNDLKIEV	EPAS1	486	Q99814
DVDIADVAYYFEKDV	EPCAM	206	P16422
LKKEEYYEVLEHTSD	AIPL1	241	Q9NZN9
YEILYKDVFVVDEEE	ALG13	366	Q9NP73
KEYEGYEVESSLEDA	CTAGE4	101	Q8IX94
KEYEGYEVESSLEDA	CTAGE6	101	Q86UF2
KEYEGYEVESSLEDA	CTAGE8	101	P0CG41
KEYEGYEVESSLEDA	CTAGE9	101	A4FU28
KEYEGYEVESSLEDA	CTAGE15	101	A4D2H0
EEDIVYYDAKADAEL	CACNA2D2	156	Q9NY47
YMYSDEIDLEADTVL	BTBD6	196	Q96KE9
EYEEILNTKLAEQYD	AKIRIN2	166	Q53H80
TLYVDADEEEIIQYV	ARC	311	Q7LC44
TAYEDVTTELEEYKE	ANKRD18B	891	A2A2Z9
VVAIYDYTKDKDDEL	ABI1	451	Q8IZP0
ITVDYIFYSAEKEDV	ANGEL2	476	Q5VTE6
DYESYLELEKTVLIN	DNAI3	861	Q8IWG1
ESGEEVEIEEFYVKY	CHD7	816	Q9P2D1
VVAIYDYTKDKEDEL	ABI2	456	Q9NYB9
EIQKALAEDATVYEY	NSRP1	61	Q9H0G5
QVLYEEATASYKEEI	AK6	126	Q9Y3D8
LEDEEIIIAEYLSYV	NUB1	591	Q9Y5A7
EEDYRYEVLTAEQIL	ARIH1	96	Q9Y4X5
SEIGEDVDYDEELYV	ANAPC1	81	Q9H1A4
IEKTYSLLLDVEDYE	PATL1	526	Q86TB9
TNAVESLDEEEKDYY	MIS18BP1	1111	Q6P0N0
LVRYAKTLYEEAEEA	NCDN	421	Q9UBB6
TVQVDDELEIKAYYA	INTS11	141	Q5TA45
EEYEVATEDGYILSV	LIPM	61	Q5VYY2
DETILDGKEYDIYVS	IL1RAP	396	Q9NPH3
DEISIDLYELEEEYY	MED22	121	Q15528
EEDKDIIQADYLYTR	FICD	151	Q9BVA6
IDKDIYQDEKTIEAY	CCDC178	326	Q5BJE1
VYLENYIKEERDSDE	FSIP2	6651	Q5CZC0
ILDYELQYYEKELSE	EPHB2	466	P29323
DAVKDLDIIDNYDYS	FLNB	891	O75369
EYSSELEKHQLYIDE	FGB	171	P02675
DRLDELEYEEVELYK	PDZD4	121	Q76G19
LEYEEVELYKSSHRD	PDZD4	126	Q76G19
ETYLKIARLYLEDDD	COPS4	146	Q9BT78
VTTIEIDEETYEEIY	LSM3	61	P62310
RDQEEEYKSKYEEEA	KRT78	191	Q8N1N4
DDAVYLDNEKEREEY	F13A1	191	P00488
ELEDVFYQYDVKSEI	MLKL	381	Q8NB16
YYDVMSDEEIERIKE	P4HA2	341	O15460
DKLDYEETKSYEIQV	PCDHA1	306	Q9Y5I3
VIDDTTKEVVYRDYI	DLST	301	P36957
RLELSVLYKEYAEDD	OTUB1	51	Q96FW1
EEDEEDTYYTKDLPI	UPF1	106	Q92900
EAYEVLSNDEKRDIY	DNAJB7	51	Q7Z6W7
VIVYYIEDDGEIISD	CD109	531	Q6YHK3
FALEDESYEIYVEDL	IL33	136	O95760
LDYETVIEELEKTYR	DOCK10	51	Q96BY6
DAVAEIDALYDVYLD	DNASE1	161	P24855
DLREKSAIYQLEEEY	DSP	241	P15924
VIEYQEEELLDKVYS	CCZ1	121	P86791
VIEYQEEELLDKVYS	CCZ1B	121	P86790
VAYEYTEAEDKSIRL	KCNMB4	6	Q86W47
DYIYTAEIEVTEENV	KLHL3	106	Q9UH77
GYEDEYVLEDLEVTV	COPG1	746	Q9Y678
YDEDYQELIEDIVRD	SCUBE2	921	Q9NQ36
DEYIELLYEDIPDKV	KIFAP3	136	Q92845
DDEVIELIVKYSNLY	PGBD3	151	Q8N328
LYVQETEKAEEALYI	SYNC	71	Q9H7C4
LVEYDIDEVVYDEDS	SMS	131	P52788
EEYIEYLKSSDRLDE	XAB2	181	Q9HCS7
ELNYYDLVRTEIAEE	SOS2	196	Q07890
NDYFYEIITEDVLEI	TDRD6	1651	O60522
EYEYVSDDGELKIDE	PHF2	676	O75151
ELDTEYYAVGKEDEE	MIA3	306	Q5JRA6
TEEKEKYDEEISSLY	KIF5C	411	O60282
KYDEEISSLYRQLDD	KIF5C	416	O60282
YLLDKDLIIDEDTLY	RASGRF2	1211	O14827
IIEEKARIIYEDYIS	RGS20	306	O76081
LDELVQSLKEYADYE	MTRF1L	356	Q9UGC7
QSLKEYADYESLVEI	MTRF1L	361	Q9UGC7
IITYDLIKYDVEKDE	SLC27A2	391	O14975
LEAVVDYTKVDRSYE	TAF2	891	Q6P1X5
DTDIYRDVAEYSEAK	SLC26A6	521	Q9BXS9
ETDVYIDIDAYEEVK	SLC26A5	516	P58743
ISEEIYDDVEYSRKE	FYB2	486	Q5VWT5
EDLYEILDSFTEKYE	SH3YL1	201	Q96HL8
EEQKLYTDDEDDIYK	SCG2	221	P13521
STYEDRLYDVEIKEN	SI	1056	P14410
YYKAKVSEEENDIEE	OLFML2B	301	Q68BL8
REDVYDVVEGYIKIS	URB1	61	O60287
RDSDIEEYLSLAYKE	SPAG17	1656	Q6Q759
YIEKSAEELDEEVEY	BRPF1	201	P55201
IHYDLVGKYETLEED	CHST11	271	Q9NPF2
DYRRTVTEIDEKEYI	PSME3	201	P61289
DDSLVDVYYREGKEE	PDCD11	1496	Q14690
LTDYFLKDEYEAEIN	USP4	326	Q13107
SEVLDELYRVSKEYT	TNFAIP8L2	36	Q6P589
SDDDDRDIEYYEKVI	TSPYL2	596	Q9H2G4
YFEEYGKIDTIEIIT	HNRNPA2B1	131	P22626
AKVEEILEQADYLYE	RMDN1	81	Q96DB5
IDIYEKEEAFEIDYS	SMC1B	966	Q8NDV3
VYKVLELYEEAVDLA	VPS18	716	Q9P253
DYEDLLVEYLEVDDS	PRLR	306	P16471
DELNDSEVYEKVVDY	ZNF292	471	O60281
DIYYASEIEEICLVD	NF1	1781	P21359
EYEREDNYGEDIKTE	TTC14	711	Q96N46
DLRDEIKECYDVYSV	PKD2	336	Q13563
REEVALSEYKTETYD	MAP2	1356	P11137
AEKYSQKEDRYEEEI	TPM1	211	P09493
YEEYSLIQETIEEKK	TLN2	126	Q9Y4G6
LLDVTDEEIYYVAKD	PNISR	346	Q8TF01
SSEEVVEIEYVEKYT	WDR12	76	Q9GZL7
DTEKTVTAEYELEYL	UGGT2	1076	Q9NYU1
YESDEDKSDYNLVVD	TLE2	226	Q04725
LNSDDYEYEDEAKLV	USP13	126	Q92995
TLVEDEEDLYDCVYG	VAV3	151	Q9UKW4
DVILEADYTLEYEEL	MUC12	5236	Q9UKN1
KEDKIEAEAEVELYY	NAA25	186	Q14CX7
NYYEDLTAKDIEEII	NDUFV2	191	P19404