Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

PMS1 AGO2 RTCB DUS4L ERVK-10 IARS2 DDX46 AGO1 DQX1 DROSHA INTS11 ERVK-8 HELZ2 DHX32 CHD6 FTO GEN1 DDX11L8

3.07e-0664515618GO:0140640
GeneOntologyMolecularFunctioncatalytic activity, acting on RNA

AGO2 RTCB DUS4L ERVK-10 IARS2 DDX46 AGO1 DROSHA INTS11 ERVK-8 HELZ2 DHX32 FTO DDX11L8

5.20e-0641715614GO:0140098
GeneOntologyMolecularFunctionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

AGO2 ERVK-10 DROSHA ERVK-8 GEN1

2.89e-05461565GO:0016893
GeneOntologyMolecularFunctionRNA endonuclease activity

AGO2 ERVK-10 AGO1 DROSHA INTS11 ERVK-8

3.59e-05791566GO:0004521
GeneOntologyMolecularFunctionflavin adenine dinucleotide binding

PYROXD1 DUS4L AOX1 PRODH2 DLD NOS2

9.54e-05941566GO:0050660
GeneOntologyMolecularFunctionRNA nuclease activity

AGO2 ERVK-10 AGO1 DROSHA INTS11 ERVK-8 HELZ2

9.76e-051361567GO:0004540
GeneOntologyMolecularFunctionendonuclease activity

AGO2 ERVK-10 AGO1 DROSHA INTS11 ERVK-8 GEN1

9.76e-051361567GO:0004519
GeneOntologyMolecularFunctionRNA polymerase binding

ERBB2 AGO2 PHRF1 AGO1 PKN2

1.55e-04651565GO:0070063
GeneOntologyMolecularFunctionL-glutamate uniporter activity

SLC17A8 SLC17A6

1.81e-0431562GO:0140788
GeneOntologyMolecularFunctionRNA endonuclease activity, producing 5'-phosphomonoesters

AGO2 ERVK-10 DROSHA ERVK-8

1.94e-04371564GO:0016891
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-9 ERVK-10 ERVK-8 ERVK-18

1.94e-04371564GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-9 ERVK-10 ERVK-8 ERVK-18

2.15e-04381564GO:0070001
GeneOntologyMolecularFunction[heparan sulfate]-glucosamine N-sulfotransferase activity

NDST4 NDST3

3.60e-0441562GO:0015016
GeneOntologyMolecularFunctionN-acetylglucosamine deacetylase activity

NDST4 NDST3

3.60e-0441562GO:0050119
GeneOntologyMolecularFunctionnuclease activity

AGO2 ERVK-10 AGO1 DROSHA INTS11 ERVK-8 HELZ2 GEN1

4.75e-042311568GO:0004518
GeneOntologyMolecularFunctioninorganic diphosphate phosphatase activity

PPA2 ALPL

5.97e-0451562GO:0004427
GeneOntologyMolecularFunctionmembrane potential driven uniporter activity

SLC17A8 SLC17A6

5.97e-0451562GO:0022810
GeneOntologyMolecularFunctionATP hydrolysis activity

PMS1 DNAH7 DDX46 SMC3 DQX1 HELZ2 DHX32 CHD6 DDX11L8 DYNC1H1 ALPL

7.12e-0444115611GO:0016887
GeneOntologyMolecularFunctionHsp90 protein binding

ERBB2 AGO2 USP19 NOS2

8.97e-04551564GO:0051879
GeneOntologyMolecularFunctionhelicase activity

DDX46 DQX1 HELZ2 DHX32 CHD6 DDX11L8

1.53e-031581566GO:0004386
GeneOntologyMolecularFunctionhydrolase activity, acting on ester bonds

AGO2 INPP5A ERVK-10 SGPP1 NDST3 IARS2 PTPN12 AGO1 DROSHA PPA2 INTS11 ERVK-8 HELZ2 GEN1 ALPL

1.67e-0380715615GO:0016788
GeneOntologyBiologicalProcesspre-miRNA processing

AGO2 AGO1 DROSHA DGCR8

6.26e-06171524GO:0031054
GeneOntologyCellularComponentendoribonuclease complex

AGO2 AGO1 DROSHA DGCR8

1.59e-04371554GO:1902555
GeneOntologyCellularComponentpericellular basket

SLC17A8 SLC17A6

1.63e-0431552GO:1990030
GeneOntologyCellularComponentribonuclease III complex

DROSHA DGCR8

1.63e-0431552GO:1903095
GeneOntologyCellularComponentmicroprocessor complex

DROSHA DGCR8

1.63e-0431552GO:0070877
GeneOntologyCellularComponentendonuclease complex

AGO2 AGO1 DROSHA DGCR8

2.87e-04431554GO:1905348
GeneOntologyCellularComponentHULC complex

UBE2A UBE2B

3.25e-0441552GO:0033503
GeneOntologyCellularComponentXY body

ATR UBE2A UBE2B

6.35e-04231553GO:0001741
DomaincEGF

HMCN1 LRP2 LTBP3 FBN3

5.34e-05261514PF12662
DomaincEGF

HMCN1 LRP2 LTBP3 FBN3

5.34e-05261514IPR026823
DomainEGF_CA

FAT4 CRTAC1 HMCN1 LRP2 LTBP3 FBN3

6.98e-05861516PF07645
DomainCRAL-bd_toc_tran

SEC14L3 SEC14L6 SEC14L4

1.08e-04121513IPR001071
DomainCRAL_TRIO_N

SEC14L3 SEC14L6 SEC14L4

1.08e-04121513SM01100
DomainEGF_3

FAT4 CRTAC1 SSPOP TMEFF1 HMCN1 LRP2 ADAM2 LTBP3 FBN3

1.27e-042351519PS50026
DomainEGF_Ca-bd_CS

FAT4 CRTAC1 HMCN1 LRP2 LTBP3 FBN3

1.36e-04971516IPR018097
DomainEGF_CA

FAT4 CRTAC1 HMCN1 LRP2 LTBP3 FBN3

1.53e-04991516PS01187
DomainFork-head_N

FOXA1 FOXA2

1.94e-0431512IPR013638
DomainGATA_N

GATA6 GATA5

1.94e-0431512IPR008013
DomainForkhead_box_C

FOXA1 FOXA2

1.94e-0431512IPR018533
DomainPC_rep

PSMD1 ANAPC1

1.94e-0431512PF01851
DomainForkhead_N

FOXA1 FOXA2

1.94e-0431512PF08430
DomainHNF_C

FOXA1 FOXA2

1.94e-0431512PF09354
DomainGATA-N

GATA6 GATA5

1.94e-0431512PF05349
DomainProteasome/cyclosome_rpt

PSMD1 ANAPC1

1.94e-0431512IPR002015
DomainCRAL/TRIO_N_dom

SEC14L3 SEC14L6 SEC14L4

2.19e-04151513IPR011074
DomainEGF_1

FAT4 CRTAC1 SSPOP TMEFF1 HMCN1 LRP2 ADAM2 LTBP3 FBN3

2.34e-042551519PS00022
DomainGrowth_fac_rcpt_

ERBB2 FAT4 IGFBP5 HMCN1 LRP2 LTBP3 FBN3

2.80e-041561517IPR009030
DomainEGF_2

FAT4 CRTAC1 SSPOP TMEFF1 HMCN1 LRP2 ADAM2 LTBP3 FBN3

3.11e-042651519PS01186
DomainHeparan_SO4_deacetylase

NDST4 NDST3

3.85e-0441512IPR021930
DomainArgonaute_N

AGO2 AGO1

3.85e-0441512IPR032474
DomainArgonaute_Mid_dom

AGO2 AGO1

3.85e-0441512IPR032473
DomainArgoL2

AGO2 AGO1

3.85e-0441512IPR032472
DomainHSNSD

NDST4 NDST3

3.85e-0441512PF12062
DomainArgoN

AGO2 AGO1

3.85e-0441512PF16486
DomainArgoMid

AGO2 AGO1

3.85e-0441512PF16487
DomainArgoL2

AGO2 AGO1

3.85e-0441512PF16488
DomainGOLD_dom

SEC14L3 SEC14L6 SEC14L4

4.56e-04191513IPR009038
DomainGOLD

SEC14L3 SEC14L6 SEC14L4

4.56e-04191513PS50866
DomainEGF_CA

FAT4 CRTAC1 HMCN1 LRP2 LTBP3 FBN3

4.73e-041221516SM00179
DomainEGF-like_Ca-bd_dom

FAT4 CRTAC1 HMCN1 LRP2 LTBP3 FBN3

5.16e-041241516IPR001881
DomainCRAL_TRIO

SEC14L3 SEC14L6 SEC14L4

6.19e-04211513PF00650
DomainDUF1785

AGO2 AGO1

6.39e-0451512SM01163
Domain-

SEC14L3 SEC14L6 SEC14L4

8.15e-042315133.40.525.10
DomainArgoL1

AGO2 AGO1

9.53e-0461512PF08699
DomainArgoL1

AGO2 AGO1

9.53e-0461512IPR014811
DomainSEC14

SEC14L3 SEC14L6 SEC14L4

1.05e-03251513SM00516
DomainASX_HYDROXYL

FAT4 HMCN1 LRP2 LTBP3 FBN3

1.31e-031001515PS00010
DomainCRAL_TRIO

SEC14L3 SEC14L6 SEC14L4

1.31e-03271513PS50191
DomainTB

LTBP3 FBN3

1.33e-0371512PF00683
DomainhEGF

FAT4 LTBP3 FBN3

1.46e-03281513PF12661
DomainCRAL-TRIO_dom

SEC14L3 SEC14L6 SEC14L4

1.46e-03281513IPR001251
DomainEGF-type_Asp/Asn_hydroxyl_site

FAT4 HMCN1 LRP2 LTBP3 FBN3

1.70e-031061515IPR000152
DomainPIWI

AGO2 AGO1

1.76e-0381512PS50822
DomainPiwi

AGO2 AGO1

1.76e-0381512SM00950
Domain-

LTBP3 FBN3

1.76e-03815123.90.290.10
DomainPiwi

AGO2 AGO1

1.76e-0381512PF02171
DomainPiwi

AGO2 AGO1

1.76e-0381512IPR003165
DomainPAZ

AGO2 AGO1

2.25e-0391512PS50821
DomainPAZ

AGO2 AGO1

2.25e-0391512SM00949
DomainTB_dom

LTBP3 FBN3

2.25e-0391512IPR017878
DomainPAZ

AGO2 AGO1

2.25e-0391512PF02170
DomainTB

LTBP3 FBN3

2.25e-0391512PS51364
DomainPAZ_dom

AGO2 AGO1

2.25e-0391512IPR003100
PathwayWP_EXRNA_MECHANISM_OF_ACTION_AND_BIOGENESIS

AGO2 DROSHA DGCR8

8.36e-0661073M39578
PathwayREACTOME_MICRORNA_MIRNA_BIOGENESIS

AGO2 AGO1 DROSHA DGCR8

3.51e-05251074M712
Pubmed

The zinc finger-containing transcription factor Gata-4 is expressed in the developing endocrine pancreas and activates glucagon gene expression.

GATA6 GATA5 FOXA1 FOXA2

6.26e-096159415539431
Pubmed

An Interaction Landscape of Ubiquitin Signaling.

AGO2 KLHDC2 ADCK5 PSMD1 APLP2 USP19 SGPP1 DDX46 ACTL8 DROSHA USP40 LRP2 DHX32 HERC2 ALPL

6.87e-094811591528190767
Pubmed

Forkhead box A1 regulates prostate ductal morphogenesis and promotes epithelial cell maturation.

PTCH1 FOXA1 FOXA2 AR

8.65e-0810159415987773
Pubmed

Association of a common AGO1 variant with lung cancer risk: a two-stage case-control study.

AGO2 AGO1 DROSHA DGCR8

8.65e-0810159420721975
Pubmed

Argonaute, Dicer, and Drosha are up-regulated along tumor progression in serous ovarian carcinoma.

AGO2 AGO1 DROSHA

3.74e-074159322647351
Pubmed

Quantitative functions of Argonaute proteins in mammalian development.

AGO2 AGO1 DGCR8

9.31e-075159322474261
Pubmed

Foxa1 and Foxa2 orchestrate development of the urethral tube and division of the embryonic cloaca through an autoregulatory loop with Shh.

PTCH1 FOXA1 FOXA2

9.31e-075159332645357
Pubmed

Single nucleotide polymorphisms of microRNA machinery genes modify the risk of renal cell carcinoma.

AGO2 AGO1 DROSHA DGCR8

1.22e-0618159419047128
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

FAT4 SSPOP TUFM TMEM260 MST1 KMT2C DQX1 DROSHA TBC1D14 PKHD1 LRP2 UTP20 CHD6 FBN3 DYNC1H1

1.62e-067361591529676528
Pubmed

Upregulation of Cyclin B1 by miRNA and its implications in cancer.

AGO2 AGO1 DROSHA

1.86e-066159322053081
Pubmed

Expression levels of the microRNA maturing microprocessor complex component DGCR8 and the RNA-induced silencing complex (RISC) components argonaute-1, argonaute-2, PACT, TARBP1, and TARBP2 in epithelial skin cancer.

AGO2 AGO1 DGCR8

1.86e-066159322025453
Pubmed

Expression of Foxa transcription factors in the developing and adult murine prostate.

FOXA1 FOXA2 AR

1.86e-066159315389796
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

TCF20 RTCB PHRF1 PSMD1 TUFM IARS2 DDX46 ANAPC1 HELZ2 DLD UTP20 HERC2 RPL5 DYNC1H1

2.04e-066531591422586326
Pubmed

Gata4 expression in lateral mesoderm is downstream of BMP4 and is activated directly by Forkhead and GATA transcription factors through a distal enhancer element.

GATA6 GATA5 FOXA2

3.24e-067159315987774
Pubmed

GATA factors and androgen receptor collaborate to transcriptionally activate the Rhox5 homeobox gene in Sertoli cells.

GATA6 GATA5 AR

3.24e-067159318212046
Pubmed

Genetic variations in microRNA-related genes are novel susceptibility loci for esophageal cancer risk.

AGO2 AGO1 DROSHA DGCR8

4.94e-0625159419138993
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

STRN3 MACC1 RTCB KDM5A PHRF1 APLP2 TUFM NDUFS5 EEF1A1P5 KMT2C DDX46 IGFBP5 ANAPC1 DROSHA RPUSD3 INTS11 HELZ2 UTP20 CHD6 DGCR8 HERC2

5.10e-0614971592131527615
Pubmed

Black carbon exposures, blood pressure, and interactions with single nucleotide polymorphisms in MicroRNA processing genes.

AGO2 AGO1 DROSHA

5.16e-068159320211803
Pubmed

Suppression of microRNA Activity in Kidney Collecting Ducts Induces Partial Loss of Epithelial Phenotype and Renal Fibrosis.

AGO2 AGO1 DGCR8

5.16e-068159329021386
Pubmed

MicroRNAs 24 and 27 Suppress Allergic Inflammation and Target a Network of Regulators of T Helper 2 Cell-Associated Cytokine Production.

AGO2 AGO1 DGCR8

5.16e-068159326850657
Pubmed

Subtypes of medulloblastoma have distinct developmental origins.

PTCH1 FOXA1 LRRN3 IGFBP5 SEMA6A

6.48e-0657159521150899
Pubmed

Hrs, a FYVE finger protein localized to early endosomes, is implicated in vesicular traffic and required for ventral folding morphogenesis.

GATA6 GATA5 FOXA1

7.72e-069159310364163
Pubmed

A dicer-independent miRNA biogenesis pathway that requires Ago catalysis.

AGO2 AGO1 DROSHA

7.72e-069159320424607
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

STRN3 AGO2 TTC28 ATG13 SH3GL1 FHIP2A DNAH7 PLEKHG1 IARS2 AGO1 LRP2 DLD HERC2 DYNC1H1 WDR62

9.53e-068531591528718761
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ERBB2 AGO2 TTC28 KDM5A AOX1 PHRF1 FOXA1 TUFM THADA ACTL8 ANAPC1 DROSHA INTS11 LRP2 SIGLEC1 WDR62 ALPL

1.53e-0511161591731753913
Pubmed

Foxa1 and Foxa2 are required for formation of the intervertebral discs.

PTCH1 FOXA1 FOXA2

2.00e-0512159323383217
Pubmed

The androgen receptor directly targets the cellular Fas/FasL-associated death domain protein-like inhibitory protein gene to promote the androgen-independent growth of prostate cancer cells.

AR CFLAR

2.08e-052159215731171
Pubmed

Reduced Expression of Argonaute 1, Argonaute 2, and TRBP Changes Levels and Intracellular Distribution of RNAi Factors.

AGO2 AGO1

2.08e-052159226242502
Pubmed

AR pathway activity correlates with AR expression in a HER2-dependent manner and serves as a better prognostic factor in breast cancer.

ERBB2 AR

2.08e-052159231933152
Pubmed

FTO mediated ERBB2 demethylation promotes tumor progression in esophageal squamous cell carcinoma cells.

ERBB2 FTO

2.08e-052159235524932
Pubmed

The ubiquitin-conjugating DNA repair enzyme HR6A is a maternal factor essential for early embryonic development in mice.

UBE2A UBE2B

2.08e-052159215169909
Pubmed

Endophilin A2 promotes HER2 internalization and sensitivity to trastuzumab-based therapy in HER2-positive breast cancers.

ERBB2 SH3GL1

2.08e-052159228974266
Pubmed

Posttranscriptional crossregulation between Drosha and DGCR8.

DROSHA DGCR8

2.08e-052159219135890
Pubmed

Periocular sebaceous gland carcinoma: do androgen receptor (NR3C4) and nuclear survivin (BIRC5) have a prognostic significance?

BIRC5 AR

2.08e-052159224930483
Pubmed

Differential induction of HNF-3 transcription factors during neuronal differentiation.

FOXA1 FOXA2

2.08e-05215929260895
Pubmed

Altered TNSALP expression and phosphate regulation contribute to reduced mineralization in mice lacking androgen receptor.

AR ALPL

2.08e-052159218838539
Pubmed

Dual role of deubiquitinating enzyme USP19 regulates mitotic progression and tumorigenesis by stabilizing survivin.

BIRC5 USP19

2.08e-052159235918893
Pubmed

Expressions of IGFBP-5, cFLIP in cervical intraepithelial neoplasia, cervical carcinoma and their clinical significances: a molecular pathology.

CFLAR IGFBP5

2.08e-052159219476635
Pubmed

Correlation between androgen receptor expression and pathological response rate in pre-operative HER2-positive breast cancer patients.

ERBB2 AR

2.08e-052159237264265
Pubmed

Precision glycocalyx editing as a strategy for cancer immunotherapy.

ERBB2 SIGLEC1

2.08e-052159227551071
Pubmed

Evaluation of polymorphisms in microRNA biosynthesis genes and risk of laryngeal cancer in the Polish population.

DROSHA DGCR8

2.08e-052159228155978
Pubmed

Identification of a Neuronal Receptor Controlling Anaphylaxis.

GRM7 SLC17A6

2.08e-052159226748715
Pubmed

Elevated levels of HER-2/neu and androgen receptor in clinically localized prostate cancer identifies metastatic potential.

ERBB2 AR

2.08e-052159218324648
Pubmed

Involvement of AGO1 and AGO2 in mammalian transcriptional silencing.

AGO2 AGO1

2.08e-052159216936728
Pubmed

The NMR structure of the class I human ubiquitin-conjugating enzyme 2b.

UBE2A UBE2B

2.08e-052159211885984
Pubmed

Argonaute Family Protein Expression in Normal Tissue and Cancer Entities.

AGO2 AGO1

2.08e-052159227518285
Pubmed

Expression of sarcosine metabolism-related proteins in estrogen receptor negative breast cancer according to the androgen receptor and HER-2 status.

ERBB2 AR

2.08e-052159226339363
Pubmed

Loss of PTPN12 Stimulates Progression of ErbB2-Dependent Breast Cancer by Enhancing Cell Survival, Migration, and Epithelial-to-Mesenchymal Transition.

ERBB2 PTPN12

2.08e-052159226391955
Pubmed

The Drosha-DGCR8 complex in primary microRNA processing.

DROSHA DGCR8

2.08e-052159215574589
Pubmed

Association of Polymorphic Variants in Argonaute Genes with Depression Risk in a Polish Population.

AGO2 AGO1

2.08e-052159236142498
Pubmed

Polymorphisms and expression of genes encoding Argonautes 1 and 2 in autoimmune thyroid diseases.

AGO2 AGO1

2.08e-052159229256262
Pubmed

Alternative Splicing of RAD6B and Not RAD6A is Selectively Increased in Melanoma: Identification and Functional Characterization.

UBE2A UBE2B

2.08e-052159231683936
Pubmed

Regulation of the Hippocampal Network by VGLUT3-Positive CCK- GABAergic Basket Cells.

SLC17A8 SLC17A6

2.08e-052159228559797
Pubmed

Foxa1 and Foxa2 regulate bile duct development in mice.

FOXA1 FOXA2

2.08e-052159220347503
Pubmed

Inflammation induced changes in the expression levels of components of the microRNA maturation machinery Drosha, Dicer, Drosha co-factor DGRC8 and Exportin-5 in inflammatory lesions of hidradenitis suppurativa patients.

DROSHA DGCR8

2.08e-052159226917346
Pubmed

Global miRNA dosage control of embryonic germ layer specification.

DROSHA DGCR8

2.08e-052159233953397
Pubmed

Androgen receptors and gender-specific distribution of alkaline phosphatase in human thyroid cartilage.

AR ALPL

2.08e-052159216583221
Pubmed

Renal uptake of the antiapoptotic protein survivin is mediated by megalin at the apical membrane of the proximal tubule.

BIRC5 LRP2

2.08e-052159223825075
Pubmed

The pioneer transcription factors Foxa1 and Foxa2 regulate alternative RNA splicing during thymocyte positive selection.

FOXA1 FOXA2

2.08e-052159234323272
Pubmed

Transcription factors FOXA1 and FOXA2 maintain dopaminergic neuronal properties and control feeding behavior in adult mice.

FOXA1 FOXA2

2.08e-052159226283356
Pubmed

Association study of AGO1 and AGO2 genes polymorphisms with recurrent pregnancy loss.

AGO2 AGO1

2.08e-052159231666609
Pubmed

Expression of androgen receptor in primary breast carcinoma and its relation with clinicopathologic features, estrogen, progesterone, and her-2 receptor status.

ERBB2 AR

2.08e-052159231603099
Pubmed

Transcription factors Foxa1 and Foxa2 are required for adult dopamine neurons maintenance.

FOXA1 FOXA2

2.08e-052159225249938
Pubmed

Heme enables proper positioning of Drosha and DGCR8 on primary microRNAs.

DROSHA DGCR8

2.08e-052159229170488
Pubmed

Inducible NO synthase confers chemoresistance in head and neck cancer by modulating survivin.

BIRC5 NOS2

2.08e-052159219130609
Pubmed

Alternative RISC assembly: binding and repression of microRNA-mRNA duplexes by human Ago proteins.

AGO2 AGO1

2.08e-052159223019594
Pubmed

Cooperativity and equilibrium with FOXA1 define the androgen receptor transcriptional program.

FOXA1 AR

2.08e-052159224875621
Pubmed

Immunohistochemical localization of Foxa1 and Foxa2 in mouse embryos and adult tissues.

FOXA1 FOXA2

2.08e-052159215567715
Pubmed

The evolutionarily ancient FOXA transcription factors shape the murine gut microbiome via control of epithelial glycosylation.

FOXA1 FOXA2

2.08e-052159238821056
Pubmed

Identification of a regulatory variant that binds FOXA1 and FOXA2 at the CDC123/CAMK1D type 2 diabetes GWAS locus.

FOXA1 FOXA2

2.08e-052159225211022
Pubmed

Inducible nitric oxide synthase and survivin messenger RNA expression in hepatocellular carcinoma.

BIRC5 NOS2

2.08e-052159212374680
Pubmed

Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA.

FOXA1 AR

2.08e-052159221572438
Pubmed

ErbB2 receptor immunoreactivity in prostate cancer: relationship to the androgen receptor, disease severity at diagnosis and disease outcome.

ERBB2 AR

2.08e-052159225215939
Pubmed

Loss of FOXA1/2 is essential for the epithelial-to-mesenchymal transition in pancreatic cancer.

FOXA1 FOXA2

2.08e-052159220160041
Pubmed

Meta-Analysis of Transcriptome Data Related to Hippocampus Biopsies and iPSC-Derived Neuronal Cells from Alzheimer's Disease Patients Reveals an Association with FOXA1 and FOXA2 Gene Regulatory Networks.

FOXA1 FOXA2

2.08e-052159226890743
Pubmed

Single-stranded antisense siRNAs guide target RNA cleavage in RNAi.

AGO2 AGO1

2.08e-052159212230974
Pubmed

Nucleosome-binding affinity as a primary determinant of the nuclear mobility of the pioneer transcription factor FoxA.

FOXA1 FOXA2

2.08e-052159219339686
Pubmed

Overexpression of androgen receptor and forkhead-box A1 protein in apocrine breast carcinoma.

FOXA1 AR

2.08e-052159224596370
Pubmed

Ago1 and Ago2 differentially affect cell proliferation, motility and apoptosis when overexpressed in SH-SY5Y neuroblastoma cells.

AGO2 AGO1

2.08e-052159221846468
Pubmed

Molecular determinants that govern scaRNA processing by Drosha/DGCR8.

DROSHA DGCR8

2.08e-052159233037012
Pubmed

Structural Basis for pri-miRNA Recognition by Drosha.

DROSHA DGCR8

2.08e-052159232220645
Pubmed

Cryo-EM Structures of Human Drosha and DGCR8 in Complex with Primary MicroRNA.

DROSHA DGCR8

2.08e-052159232220646
Pubmed

Microprocessor dynamics and interactions at endogenous imprinted C19MC microRNA genes.

DROSHA DGCR8

2.08e-052159222393237
Pubmed

The androgen receptor induces a distinct transcriptional program in castration-resistant prostate cancer in man.

FOXA1 AR

2.08e-052159223260764
Pubmed

Foxa1 and Foxa2 in thymic epithelial cells (TEC) regulate medullary TEC and regulatory T-cell maturation.

FOXA1 FOXA2

2.08e-052159230061015
Pubmed

Foxa1 and Foxa2 interact with the androgen receptor to regulate prostate and epididymal genes differentially.

FOXA1 FOXA2

2.08e-052159216467259
Pubmed

Reduced androgen receptor expression accelerates the onset of ERBB2 induced breast tumors in female mice.

ERBB2 AR

2.08e-052159223593223
Pubmed

Loss of HR6B ubiquitin-conjugating activity results in damaged synaptonemal complex structure and increased crossing-over frequency during the male meiotic prophase.

UBE2A UBE2B

2.08e-052159212556476
Pubmed

Pioneer of prostate cancer: past, present and the future of FOXA1.

FOXA1 AR

2.08e-052159232946061
Pubmed

Pioneer Factors FOXA1 and FOXA2 Assist Selective Glucocorticoid Receptor Signaling in Human Endometrial Cells.

FOXA1 FOXA2

2.08e-052159228938408
Pubmed

Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6.

UBE2A UBE2B

2.08e-05215921717990
Pubmed

Hepatic deficiency of the pioneer transcription factor FoxA restricts hepatitis B virus biosynthesis by the developmental regulation of viral DNA methylation.

FOXA1 FOXA2

2.08e-052159228235042
Pubmed

Coordinated expression of oestrogen and androgen receptors in HER2-positive breast carcinomas: impact on proliferative activity.

ERBB2 AR

2.08e-052159222039288
Pubmed

The role of hepatocyte nuclear factor-3 alpha (Forkhead Box A1) and androgen receptor in transcriptional regulation of prostatic genes.

FOXA1 AR

2.08e-052159212750453
Pubmed

The Fer tyrosine kinase acts as a downstream interleukin-6 effector of androgen receptor activation in prostate cancer.

AR FER

2.08e-052159223906537
Pubmed

Sequence logic at enhancers governs a dual mechanism of endodermal organ fate induction by FOXA pioneer factors.

FOXA1 FOXA2

2.08e-052159234789735
Pubmed

Localization of two human homologs, HHR6A and HHR6B, of the yeast DNA repair gene RAD6 to chromosomes Xq24-q25 and 5q23-q31.

UBE2A UBE2B

2.08e-05215921559696
Pubmed

FOXA1 regulates androgen receptor variant activity in models of castrate-resistant prostate cancer.

FOXA1 AR

2.08e-052159226336819
Pubmed

The human DiGeorge syndrome critical region gene 8 and Its D. melanogaster homolog are required for miRNA biogenesis.

DROSHA DGCR8

2.08e-052159215589161
Pubmed

Fat mass and obesity-associated protein regulates tumorigenesis of arecoline-promoted human oral carcinoma.

FOXA2 FTO

2.08e-052159234378866
InteractionUBC interactions

KLHDC2 ADCK5 PSMD1 APLP2 TUFM USP19 DDX46 DROSHA USP40 LRP2 USP12 DHX32 HERC2 ALPL

6.39e-0644615014int:UBC
GeneFamilySEC14 family|PRELI domain containing

SEC14L3 SEC14L6 SEC14L4

3.15e-0669931063
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

ANKRD42 PHRF1 IKZF1 GRM7 FER RPL5

4.81e-04181996694
GeneFamilyArgonaute/PIWI family

AGO2 AGO1

8.13e-048992408
GeneFamilySulfotransferases, membrane bound

NDST4 NDST3 CHST2

1.08e-0337993763
GeneFamilyC2 domain containing protein kinases

PRKCH PKN2

1.30e-0310992835
GeneFamilyForkhead boxes

FOXS1 FOXA1 FOXA2

1.68e-0343993508
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

GATA6 GATA5

2.98e-031599282
GeneFamilyUbiquitin specific peptidases

USP19 USP40 USP12

3.58e-0356993366
GeneFamilyOTU domain containing

OTUD6A OTUD6B

3.83e-0317992669
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BNC2 DLGAP1 MACC1 TTC28 AR PKHD1 LRP2 SEMA6A SAMD4A

2.44e-0819115591cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCellFetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RGS9 CRMP1 CFLAR PLEKHG1 HELZ2 PRKCH SEMA6A NOS2

2.34e-071801558d8ef44710a77ad0fc03243428e5e1dc4d41200cb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BNC2 DLGAP1 MACC1 TTC28 AR PKHD1 LRP2 SAMD4A

3.39e-0718915583b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCellCOVID-19-kidney-PCT-S2|kidney / Disease (COVID-19 only), tissue and cell type

BNC2 DLGAP1 MACC1 AOX1 AR PKHD1 LRP2 SAMD4A

3.39e-0718915580be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCellBronchial_Brush-Epithelial-Goblet_2|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

FAT4 ARHGEF39 CPXM1 UTP20 CHST2 NOS2 SAMD4A

1.93e-0616615578ac0a769be886d16642e7e6334471ebadd1a426b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BNC2 DLGAP1 MACC1 TTC28 PKHD1 LRP2 SAMD4A

4.24e-0618715579d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BNC2 DLGAP1 MACC1 TTC28 PKHD1 LRP2 SAMD4A

4.71e-061901557989d4eefd22d66ecb857836f8fdbcf41e3047f84
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Airway|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MACC1 SYT6 L2HGDH FOXA2 ADAM2 RIC3

4.85e-061241556a7b7d8b14d1218194da8fcf69b4780b6e9469332
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MACC1 FOXA1 DNAH7 AR PLEKHG1 PKHD1 LRP2

5.40e-061941557f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCellsevere-NK|severe / disease stage, cell group and cell class

BNC2 ERBB2 IKZF1 TBC1D10C PTPN12 PRKCH CHST2

6.17e-061981557cb505077dc5bdf3fdd513bb9032e32bb9644c004
ToppCellCOVID-19_Convalescent-Non-classical_Monocyte|COVID-19_Convalescent / Disease condition and Cell class

PSMA4 IKZF1 SGPP1 TBC1D10C TNFRSF8 CHST2 SAMD4A

6.37e-061991557c9250c80dd5bc3d27c6065b99119ff7dcf392e84
ToppCellCOVID-19_Convalescent-Non-classical_Monocyte-|COVID-19_Convalescent / Disease condition and Cell class

PSMA4 IKZF1 SGPP1 TBC1D10C TNFRSF8 CHST2 SAMD4A

6.37e-061991557996a207b8b91e10dd018dc07aaf5ecd473bfeaad
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SYT6 L2HGDH ZNF865 TBC1D10C HELZ2 SAMD4A

1.80e-051561556895927228c93cd090303984c5be6ebfb59ed6f3a
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

PMS1 FOXS1 ERBB2 PHETA1 ZNF772 CHST2

2.39e-051641556d2218d50e0e2d19f919dcb460b3840687c082810
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BIRC5 F13A1 B4GALT6 CD200R1 ARHGEF39 PKHD1

2.56e-051661556bb8135119dc37fdbba476599a56d368f422688dc
ToppCellfacs-Skin-Anagen-24m-Epithelial-inner_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PMS1 PLEKHG1 UTP20 SEMA6A HERC2

2.63e-05100155597ca9cda55a05fbb4d1f5d61f847c965e014f05c
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BNC2 SMYD1 IGFBP5 UPK1B LRP2 SLC17A8

2.64e-051671556c042d6cdddd0e1ddef1e3ac6f4fe23151127b0f2
ToppCellBronchial_Brush-Epithelial-Goblet_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

FAT4 ARHGEF39 CPXM1 UTP20 CHST2 SAMD4A

2.64e-051671556806d1c00c137da0c5f042adf866873eb6dd4bb27
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BNC2 SMYD1 IGFBP5 UPK1B LRP2 SLC17A8

2.64e-051671556351f8de1fbdf742ac74f9099b254d515ab539bb2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GATA5 PLEKHG1 IGFBP5 PRKCH SEMA6A NOS2

2.83e-051691556987ff79ad563825dd9877ea8ccb536758f8c6700
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BNC2 GATA6 IGFBP5 UPK1B SLC17A8 CPXM1

3.22e-051731556ee7d1429f23f1b89a9a9f7bc07a84a44cf7acd1c
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BNC2 GATA6 IGFBP5 UPK1B SLC17A8 CPXM1

3.22e-0517315563725525b99a6011eda2ff5459b4fd2e1eab1f090
ToppCelldroplet-Lung-LUNG-30m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MACC1 FOXA2 SUSD5 PKHD1 LRP2 CCDC33

3.55e-0517615565201f003192c033655ba47f0faf8c47a96eae03d
ToppCell3'-Adult-LargeIntestine-Hematopoietic-T_cells-SELL+_CD4_T|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IKZF1 CD200R1 TBC1D10C LRRN3 PRKCH RIC3

3.66e-051771556bb496fbec7cacc52847abe2b2714249c47879763
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BNC2 SMYD1 IGFBP5 UPK1B LRP2 CPXM1

3.78e-051781556bcbdd45a2307f8aea14122fa0144b96b1f6eec48
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SMYD1 GATA5 B4GALT6 IGFBP5 UPK1B LRP2

3.78e-0517815561e05bc26591fea16e29bcfc5f538dda1dc427f05
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BNC2 SMYD1 IGFBP5 UPK1B LRP2 CPXM1

3.78e-051781556c413861148129be1ee94f2ceb5999840217eebe5
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

BNC2 DLGAP1 GRM7 DNAH7 PKHD1 LRP2

3.78e-051781556544379f5a6145429762258d426b876bb36c112f5
ToppCellCOVID-19-kidney-PCT-S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

BNC2 DLGAP1 MACC1 AOX1 PKHD1 LRP2

4.02e-051801556358923e4228035a3e90e2957392089219e90dcd7
ToppCellCOVID-19-kidney-tDL|COVID-19 / Disease (COVID-19 only), tissue and cell type

BNC2 DLGAP1 AOX1 ALDH8A1 PKHD1 LRP2

4.02e-051801556864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BNC2 FAT4 AOX1 PTCH1 IGFBP5 HMCN1

4.15e-051811556b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCellCOVID-19-kidney-Stressed_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

SYT6 AOX1 ALDH8A1 PRODH2 PKHD1 LRP2

4.15e-0518115566980ea624151da32b7f537f263e40fcb87a02e81
ToppCellCOVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type

MACC1 AOX1 ALDH8A1 DNAH7 PKHD1 LRP2

4.41e-0518315566878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCellPCW_05-06-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MACC1 FOXA1 PLEKHG1 PKHD1 LRP2 ALPL

4.41e-051831556c5b10571599dc26476170b54b53f09c23e6b3117
ToppCellE15.5-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

BNC2 SMYD1 IGFBP5 UPK1B LRP2 CPXM1

4.41e-051831556274f274cf60daa30d6a4cd603a3af7823bfb8016
ToppCellMesenchymal_cells-Osteo-CAR|World / Lineage and Cell class

FAT4 SYT6 IGFBP5 CPXM1 CHST2 ALPL

4.69e-05185155616f1588893d09c864e0cb4f837a1b972a1a57baa
ToppCelldroplet-Lung-LUNG-1m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLGAP1 MACC1 DUS4L FOXA2 LRP2 SEC14L4

4.83e-051861556e52cf44989c57c433bf82e9fa13b4643e88f3577
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

BNC2 DLGAP1 MACC1 TTC28 PKHD1 LRP2

4.83e-051861556b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCelldroplet-Lung-LUNG-1m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLGAP1 MACC1 DUS4L FOXA2 LRP2 SEC14L4

4.83e-0518615564c0b59d845b79323e7a3287e7c4d249f5f322556
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BNC2 DLGAP1 STRN3 DNAH7 PKHD1 SPAG16

4.97e-051871556c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCellpdx-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

TCF20 PTCH1 CPXM1 BAMBI SEMA6A CCDC33

4.97e-0518715567e376831a11ee72ed87abcdac631ca46ae29c250
ToppCelldroplet-Kidney-KIDNEY-1m-Endothelial-kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GATA5 IGFBP5 BAMBI PRKCH SEMA6A CHST2

5.12e-051881556b651024d58ed1bcfe0d80b21755f8bf709eda81f
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MACC1 FOXA1 AR PLEKHG1 PKHD1 LRP2

5.12e-051881556beb2df2332a46cc81b10e8e29fc9829020111f03
ToppCelldroplet-Kidney-KIDNEY-1m-Endothelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GATA5 IGFBP5 BAMBI PRKCH SEMA6A CHST2

5.12e-05188155651c6796a9488c056a10d048082015342c2e037f9
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BNC2 STRN3 DNAH7 PKHD1 SPAG16 SAMD4A

5.12e-051881556af740fa78542438fdff627ea1f74f4eee43316be
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

BNC2 DLGAP1 MACC1 AR PKHD1 LRP2

5.28e-05189155628b502611829e4a24caff2562545c7db97686099
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MACC1 FOXA1 AR PLEKHG1 PKHD1 LRP2

5.43e-051901556625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCelldroplet-Lung-21m-Epithelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MACC1 CDS1 FOXA1 FOXA2 LRP2 SEC14L4

5.43e-05190155650a8ba20f8153279387c335538bc52bf18ac1fc2
ToppCell15-Distal-Mesenchymal-Mesenchyme_SERPINF1-high|Distal / Age, Tissue, Lineage and Cell class

FOXS1 BNC2 IGFBP5 TNFRSF8 UPK1B RIC3

5.43e-051901556b47472dc9fe6ed99c2365203a3d8a59879e74a70
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_intermediate_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MACC1 FOXA1 AR PLEKHG1 PKHD1 LRP2

5.43e-051901556c95032bb3ee2b3d40fdf48016acb46d6f78a48a6
ToppCellwk_08-11-Epithelial-Airway_epithelial_progenitor-epi-stalk_early|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

BIRC5 FOXA1 FOXA2 TMEFF1 PLEKHG1 ALPL

5.43e-0519015569f5f65869dad9a43ac94f81f9a19c72ffe5adc3c
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MACC1 FOXA1 DNAH7 PLEKHG1 PKHD1 LRP2

5.59e-05191155660ff989fe99d243a3d52955223680cdd1f1917a4
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

BNC2 DLGAP1 HDHD3 AOX1 PKHD1 LRP2

5.59e-0519115561c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCellfacs-Lung-EPCAM-3m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDS1 FOXA1 FOXA2 SEC14L3 LRP2 SEC14L4

5.59e-051911556629007189034ee8451411428f1c6cc57daee2d91
ToppCelldroplet-Lung-18m-Epithelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MACC1 FOXA1 FOXA2 SEC14L3 LRP2 SEC14L4

5.59e-0519115561b59f1cad6c1a6a5938afa9195164918e3ff4e86
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

BNC2 DLGAP1 HDHD3 AOX1 PKHD1 LRP2

5.59e-0519115563c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellFetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RGS9 CRMP1 PLEKHG1 PRKCH SEMA6A NOS2

5.59e-0519115561de0bdfd13bd930691564c2673f2e66393bc0255
ToppCellEndothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|World / Lineage, Cell type, age group and donor

RGS9 CRMP1 PLEKHG1 PRKCH SEMA6A NOS2

5.76e-0519215561e156bab5ecf64627890d2de9b27603d9a01f28d
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MACC1 FOXA1 AR PLEKHG1 PKHD1 LRP2

5.76e-051921556d3634574b2e8d2ded6446969361b70761b331aea
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MACC1 FOXA1 AR PLEKHG1 PKHD1 LRP2

5.76e-05192155625378b5e4b0cea8415ff125783511fc25a56fc00
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

BNC2 FAT4 NDST4 PTCH1 NDST3 PLEKHG1

5.76e-05192155672881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCellControl-B_intermediate-10|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

CD200R1 PTPN12 SUSD5 PRKCH GEN1 LRRC73

5.76e-051921556224bd958369ba8fa0d7be2126f7dc61c9f6ac19d
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MACC1 FOXA1 DNAH7 PLEKHG1 PKHD1 LRP2

5.76e-051921556b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCellfacs-Lung-nan-3m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDS1 FOXA1 FOXA2 SEC14L3 LRP2 SEC14L4

5.76e-051921556cca2d0fedfbd946c54d6f4fc45887117c8dae58a
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MACC1 FOXA1 AR PLEKHG1 PKHD1 LRP2

5.76e-0519215561aa5e4d9b32013a3f272561dcb8377f6805706df
ToppCellStriatum-Hematopoietic-MACROPHAGE|Striatum / BrainAtlas - Mouse McCarroll V32

ALDH8A1 F13A1 CD200R1 TNFRSF8 SIGLEC1

5.82e-05118155554930a3faa055bda4a707b93d790b2ac5a360211
ToppCellStriatum-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)|Striatum / BrainAtlas - Mouse McCarroll V32

ALDH8A1 F13A1 CD200R1 TNFRSF8 SIGLEC1

5.82e-05118155518f9c1759df9504962612ec741638ed330c33222
ToppCellStriatum-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)-|Striatum / BrainAtlas - Mouse McCarroll V32

ALDH8A1 F13A1 CD200R1 TNFRSF8 SIGLEC1

5.82e-05118155597db1193ecc885f63840663ab969468ce21cba74
ToppCellStriatum-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)--|Striatum / BrainAtlas - Mouse McCarroll V32

ALDH8A1 F13A1 CD200R1 TNFRSF8 SIGLEC1

5.82e-0511815550c2fe46dd66e0c9cdf8c2eb66874aca79592248a
ToppCellStriatum-Hematopoietic-MACROPHAGE-MP1(C1qb)|Striatum / BrainAtlas - Mouse McCarroll V32

ALDH8A1 F13A1 CD200R1 TNFRSF8 SIGLEC1

5.82e-0511815553f8d11e09a7660af9eca5249ad698d9b638d39dd
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

DLGAP1 TTC28 KDM5A UBE2B FER CHD6

5.93e-051931556e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 GATA5 PTPN12 IGFBP5 PRKCH SEMA6A

5.93e-051931556456aa8a8f1f9cbba0bd618a5f623909079c0f56b
ToppCellCF-Lymphoid-B_cell|Lymphoid / Disease state, Lineage and Cell class

MACC1 SGPP1 PLEKHG1 FER GEN1 SAMD4A

5.93e-0519315567ebf20344a9a154fd2cffa281526867fcf0aded3
ToppCellInt-URO-Lymphocyte-T_NK-NK|Int-URO / Disease, Lineage and Cell Type

BNC2 ERBB2 RGS9 TBC1D10C PRKCH CHST2

5.93e-0519315565c7942f630fc69374df34ee3602ad973b6ced17a
ToppCellfacs-Lung-3m-Epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDS1 FOXA1 FOXA2 SEC14L3 LRP2 SEC14L4

5.93e-051931556db5e43e0b571737e7006365bdf0575340b8b900b
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell-Mesothelium|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BNC2 AOX1 GATA6 GATA5 MST1 CPXM1

6.10e-051941556c578cf7c6b4d6f31f87dde8845de5b3891f16822
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibro-meso|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BNC2 AOX1 GATA6 GATA5 MST1 CPXM1

6.10e-051941556f4286ae7bb8350c42d50727ee8688b80129714f6
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BNC2 AOX1 GATA6 GATA5 MST1 CPXM1

6.10e-05194155687461bd6d7f702c0a0f5e0c8ace3049125a51f9a
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MACC1 FOXA1 DNAH7 PLEKHG1 PKHD1 LRP2

6.10e-0519415566b286992d4bb56013c0ea5a7601d3476d806175a
ToppCellPCW_07-8.5-Epithelial|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MACC1 FOXA1 AR PLEKHG1 PKHD1 LRP2

6.10e-051941556f63ceedb88a9abc8644ee94adfd541e7817c1e3a
ToppCellfacs-Skin-Anagen-3m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAPK8IP1 BNC2 APLP2 SGPP1 HMCN1 LTBP3

6.10e-0519415565d30d3d41d5f19cdf3077cc609aa2738762cb8c5
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GATA6 APLP2 B4GALT6 NDUFS5 IGFBP5 HMCN1

6.10e-051941556c5e77650d7abee339ec38fa78a622bb124db3fa5
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_NK-natural_killer_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

BNC2 ERBB2 RGS9 PTPN12 PRKCH CHST2

6.10e-051941556a3a81638b55cb5fc08fe83c8b88f68d49b87e6cb
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_NK-natural_killer_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

BNC2 ERBB2 RGS9 PTPN12 PRKCH CHST2

6.10e-0519415560abca32c3547a45cebab0bd69c1f7a0002deaa80
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

DLGAP1 PTCH1 CRMP1 NDST3 BAMBI CHST2

6.27e-051951556c5d2d9f12fd893331c9de261af30607d845d4f6a
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

BNC2 ERBB2 RGS9 TBC1D10C PRKCH CHST2

6.45e-051961556d3bd8fab010e76024d7e06aba0ea5df3394f411f
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

BNC2 ERBB2 RGS9 TBC1D10C PRKCH CHST2

6.45e-05196155677da6b1bcab45d376eb0368f540e0ed24ce98b42
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_NK-NK_dim-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

BNC2 ERBB2 RGS9 PTPN12 PRKCH CHST2

6.45e-051961556c25f90c4e5abfe7cfaa85bfe136c438a5179c978
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_NK-NK_dim|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

BNC2 ERBB2 RGS9 PTPN12 PRKCH CHST2

6.45e-051961556d451f279f4086fcf727af712f98923551181c76e
ToppCellCOVID-19_Severe-Lymphoid_T/NK-NK|COVID-19_Severe / Disease group, lineage and cell class

BNC2 ERBB2 RGS9 TBC1D10C PRKCH CHST2

6.45e-051961556cc1daf12de5765ba4f7002396352404b41df2012
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BNC2 ERBB2 RGS9 TBC1D10C PRKCH CHST2

6.64e-0519715569993fdea353abeafc009ac87439ad25cedf8f1f6
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BNC2 FAT4 NDST4 PTCH1 F13A1 HMCN1

6.64e-05197155644673c38384453207871d3fd8e8ba9093cc06bc5
ToppCellParenchymal-10x5prime-Stromal-Mesofibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

AOX1 ALDH8A1 GATA5 MST1 UPK1B CPXM1

6.64e-05197155688a86286b9c3ea3b076d7464faec42d0392ee7f8
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BNC2 ERBB2 RGS9 TBC1D10C PRKCH CHST2

6.64e-051971556300849a922722adcbc068593fc5cc0bef936d9cb
ToppCellParenchymal-10x5prime-Stromal-Mesofibroblastic-Mesothelia|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

AOX1 ALDH8A1 GATA5 MST1 UPK1B CPXM1

6.64e-0519715562773d2eb5f232a7e49da116efffcb6bf5eb90810
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BNC2 ERBB2 RGS9 TBC1D10C PRKCH CHST2

6.64e-051971556a8b41fffa4e86f2766423392951ff320e821a19a
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-natural_killer_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ERBB2 RGS9 CFLAR PTPN12 PRKCH CHST2

6.64e-051971556550cce374332c49893bcf4ce4b7dceb7f5fe26aa
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

BNC2 ERBB2 RGS9 TBC1D10C PRKCH CHST2

6.64e-051971556a97c4a9eb89260b0b5745834ccef9d558d857f93
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BNC2 ERBB2 RGS9 PTPN12 PRKCH CHST2

6.83e-051981556eb5407908f1e43b5775d50006cc6c71e90b73660
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

BNC2 ERBB2 RGS9 PTPN12 PRKCH CHST2

6.83e-05198155656a39e44c6f97b8093e3a3815b94a1ddf906f59d
Diseasecongenital heart disease (implicated_via_orthology)

KMT2C UBE2A UBE2B LRP2 CHD6

2.57e-05691485DOID:1682 (implicated_via_orthology)
Diseasestomach cancer (is_implicated_in)

ERBB2 PTCH1 FOXA1 TMEM260 KMT2C

3.17e-05721485DOID:10534 (is_implicated_in)
Diseasesyndromic intellectual disability (implicated_via_orthology)

KDM5A UBE2A UBE2B

6.60e-05161483DOID:0050888 (implicated_via_orthology)
DiseaseIntrahepatic Cholangiocarcinoma

ERBB2 KMT2C NOS2

2.32e-04241483C0345905
DiseaseExtrahepatic Cholangiocarcinoma

ERBB2 KMT2C NOS2

2.32e-04241483C3805278
Diseasestomach carcinoma (is_marker_for)

ERBB2 KDM5A KMT2C

2.32e-04241483DOID:5517 (is_marker_for)
Diseasepulmonary embolism (is_implicated_in)

F13A1 FTO

2.47e-0451482DOID:9477 (is_implicated_in)
DiseaseIgG disialylation measurement

IKZF1 MOGAT3

2.47e-0451482EFO_0008429
Diseaseadenoid cystic carcinoma (is_implicated_in)

ATR KMT2C

2.47e-0451482DOID:0080202 (is_implicated_in)
DiseaseKlatskin's tumor (is_implicated_in)

GATA6 KMT2C

2.47e-0451482DOID:4927 (is_implicated_in)
Diseaseintraocular pressure measurement

FOXA1 THADA ANAPC1 FER PKHD1 CPXM1 BAMBI PKN2 LTBP3 HERC2

2.61e-0450914810EFO_0004695
DiseaseProstatic Neoplasms

PMS1 ERBB2 ATR AOX1 NDST4 BIRC5 FOXA1 AR KMT2C LRP2 CHD6

2.91e-0461614811C0033578
DiseaseMalignant neoplasm of prostate

PMS1 ERBB2 ATR AOX1 NDST4 BIRC5 FOXA1 AR KMT2C LRP2 CHD6

2.91e-0461614811C0376358
DiseaseCholangiocarcinoma

ERBB2 KMT2C NOS2

2.95e-04261483C0206698
DiseaseMalignant neoplasm of breast

ERBB2 CDS1 BIRC5 FOXA1 AR MST1 IGFBP5 UPK1B UTP20 DHX32 HERC2 FTO GEN1 NOS2 SLC17A6

3.41e-04107414815C0006142
DiseaseCholangitis, Sclerosing

MST1 NOS2

3.70e-0461482C0008313
DiseaseBreast Carcinoma

ERBB2 BIRC5 FOXA1 AR MST1 IGFBP5 UPK1B HERC2 FTO NOS2

4.03e-0453814810C0678222
DiseaseNeoplasm of uncertain or unknown behavior of ovary

PMS1 ERBB2 ATR

4.11e-04291483C0496920
DiseaseIntellectual Disability

TCF20 KDM5A L2HGDH FHIP2A KMT2C AGO1 LRP2 DYNC1H1 WDR62

4.45e-044471489C3714756
DiseaseOvarian Carcinoma

PMS1 ERBB2 ATR

4.55e-04301483C0029925
Diseaselanguage measurement

DLGAP1 TCF20 GRM7 PLEKHG1 PKN2

5.89e-041341485EFO_0007797
Diseaseovarian neoplasm

PMS1 BNC2 ERBB2 ATR BIRC5

5.89e-041341485C0919267
Diseasefacial morphology measurement

BNC2 DLGAP1 FAT4 GRM7 THADA PTPN12 ANAPC1 PKHD1 FTO

5.99e-044661489EFO_0007841
DiseaseMalignant neoplasm of ovary

PMS1 BNC2 ERBB2 ATR BIRC5

6.52e-041371485C1140680
Diseaseskin pigmentation measurement

BNC2 SYT6 PTCH1 ACTL8 HERC2

6.52e-041371485EFO_0007009
DiseasePrimary sclerosing cholangitis

MST1 NOS2

6.86e-0481482C0566602
DiseaseIgG digalactosylation measurement

IKZF1 MOGAT3

6.86e-0481482EFO_0008424
Diseasepulmonary hypertension (biomarker_via_orthology)

GATA6 BIRC5 ALAS1 NOS2

7.15e-04801484DOID:6432 (biomarker_via_orthology)
Diseasewhite matter microstructure measurement

BNC2 STRN3 PSMD1 PTCH1 PLEKHG1 SEC14L6 LRP2 PKN2

8.20e-043901488EFO_0005674
Diseaseneurodegenerative disease (implicated_via_orthology)

FAT4 PTCH1 SLC17A8 DYNC1H1 SLC17A6

8.42e-041451485DOID:1289 (implicated_via_orthology)
DiseaseIgG bisecting N-acetyl glucosamine measurement

IKZF1 MOGAT3

8.79e-0491482EFO_0008426
DiseaseIgG monogalactosylation measurement

IKZF1 MOGAT3

8.79e-0491482EFO_0008423
Diseaseductal carcinoma in situ (is_marker_for)

ERBB2 BIRC5 AR

9.90e-04391483DOID:0060074 (is_marker_for)
DiseaseEczema

BNC2 DLGAP1 TTC28 IKZF1 CD200R1 ANAPC1 TNFRSF8

9.99e-043101487HP_0000964
Diseaseautism spectrum disorder (implicated_via_orthology)

TCF20 KDM5A NDST4 NDST3 CHD6

1.04e-031521485DOID:0060041 (implicated_via_orthology)
Diseaseuremia (biomarker_via_orthology)

NOS2 ALPL

1.10e-03101482DOID:4676 (biomarker_via_orthology)
DiseaseIgG sialylation measurement

IKZF1 MOGAT3

1.10e-03101482EFO_0008428
Diseasebiological sex

STRN3 TTC28 PKHD1 SEMA6A FTO CCDC33

1.10e-032301486PATO_0000047
DiseaseNeoplasm of uncertain or unknown behavior of breast

ERBB2 FOXA1 HERC2

1.15e-03411483C0496956
DiseaseBreast adenocarcinoma

ERBB2 FOXA1 HERC2

1.15e-03411483C0858252
DiseaseDiaphragmatic Hernia

GATA6 FOXA2 LRP2

1.15e-03411483C0019284
Diseasecortical surface area measurement

BNC2 STRN3 INPP5A ATG13 SIDT1 CRTAC1 PTCH1 DNAH7 TUFM PLEKHG1 THADA PKHD1 PKN2 SEMA6A FBN3 CCDC33

1.21e-03134514816EFO_0010736
Diseaseage-related hearing impairment

BNC2 AGO2 TTC28 THADA FER FSCN2 FTO

1.29e-033241487EFO_0005782
Diseaseeosinophil count

BNC2 ATR PHETA1 IKZF1 FOXA1 DNAH7 NDUFS5 CD200R1 EEF1A1P5 THADA ANAPC1 TNFRSF8 TBC1D14 HELZ2 PKN2 LTBP3 NOS2

1.32e-03148814817EFO_0004842
DiseaseMammary Carcinoma, Human

ERBB2 BIRC5 FOXA1 AR MST1 IGFBP5 UPK1B FTO NOS2

1.38e-035251489C4704874
DiseaseMammary Neoplasms, Human

ERBB2 BIRC5 FOXA1 AR MST1 IGFBP5 UPK1B FTO NOS2

1.38e-035251489C1257931
Diseasebasophil count, eosinophil count

IKZF1 CD200R1 EEF1A1P5 ANAPC1 TNFRSF8 PKN2

1.40e-032411486EFO_0004842, EFO_0005090
DiseaseMammary Neoplasms

ERBB2 BIRC5 FOXA1 AR MST1 IGFBP5 UPK1B FTO NOS2

1.42e-035271489C1458155
Diseasestenosing tenosynovitis

LTBP3 FTO

1.60e-03121482EFO_0010822
DiseaseIgG galactosylation measurement

IKZF1 MOGAT3

1.60e-03121482EFO_0008425
DiseaseHodgkin lymphoma, lymphocyte depletion

CFLAR TNFRSF8

1.88e-03131482C0152267
DiseaseMixed Cellularity Hodgkin Lymphoma

CFLAR TNFRSF8

1.88e-03131482C0152266
Diseasetetralogy of Fallot (is_implicated_in)

GATA6 GATA5

1.88e-03131482DOID:6419 (is_implicated_in)
DiseaseLymphocyte Rich Classical Hodgkin Lymphoma

CFLAR TNFRSF8

1.88e-03131482C1266194
DiseaseAdult Hodgkin Lymphoma

CFLAR TNFRSF8

1.88e-03131482C0220597
DiseaseNodular Lymphocyte Predominant Hodgkin Lymphoma

CFLAR TNFRSF8

1.88e-03131482C1334968
Diseaselung adenocarcinoma (is_implicated_in)

ERBB2 PTCH1 KMT2C

1.92e-03491483DOID:3910 (is_implicated_in)
Diseasecognitive function measurement, self reported educational attainment

AGO2 TCF20 IL20RB PTCH1 PPA2 PKHD1 MOGAT3

2.16e-033551487EFO_0004784, EFO_0008354
DiseaseMetabolic Bone Disorder

LRP2 ALPL

2.19e-03141482C0005944
DiseaseMalformations of Cortical Development

DYNC1H1 WDR62

2.19e-03141482C1955869
Diseaseventricular septal defect (is_implicated_in)

GATA6 GATA5

2.19e-03141482DOID:1657 (is_implicated_in)
Diseasechromosome 22q11.2 deletion syndrome, distal (implicated_via_orthology)

PRODH2 DGCR8

2.19e-03141482DOID:0060413 (implicated_via_orthology)
Diseaseactinic keratosis

BNC2 HERC2

2.19e-03141482EFO_0002496
DiseaseCortical Dysplasia

DYNC1H1 WDR62

2.19e-03141482C0431380
DiseaseAlcoholic Intoxication, Chronic

AGO2 GRM7 AR AGO1 ANAPC1 FTO

2.39e-032681486C0001973
DiseaseOsteopenia

LRP2 ALPL

2.51e-03151482C0029453
DiseaseCarcinoma, Granular Cell

ERBB2 FAT4 BIRC5 KMT2C

2.82e-031161484C0205644
DiseaseAdenocarcinoma, Tubular

ERBB2 FAT4 BIRC5 KMT2C

2.82e-031161484C0205645
DiseaseAdenocarcinoma, Oxyphilic

ERBB2 FAT4 BIRC5 KMT2C

2.82e-031161484C0205642
DiseaseCarcinoma, Cribriform

ERBB2 FAT4 BIRC5 KMT2C

2.82e-031161484C0205643
DiseaseAdenocarcinoma, Basal Cell

ERBB2 FAT4 BIRC5 KMT2C

2.82e-031161484C0205641
DiseaseAdenocarcinoma

ERBB2 FAT4 BIRC5 KMT2C

2.82e-031161484C0001418
DiseaseTetralogy of Fallot

GATA6 GATA5

2.86e-03161482C0039685
Diseaseautosomal recessive polycystic kidney disease (implicated_via_orthology)

NEK8 PKHD1

2.86e-03161482DOID:0110861 (implicated_via_orthology)
DiseaseCleft palate, cleft lip

CRTAC1 PTCH1 CRMP1 THADA PKHD1 SAMD4A

2.91e-032791486EFO_0003959, HP_0000175
DiseaseBenign neoplasm of stomach

ERBB2 ATR

3.23e-03171482C0153943
DiseaseNeoplasm of uncertain or unknown behavior of stomach

ERBB2 ATR

3.23e-03171482C0496905
DiseaseCarcinoma in situ of stomach

ERBB2 ATR

3.23e-03171482C0154060
DiseaseAlzheimer disease, brain volume measurement

IKZF1 PKN2

3.23e-03171482EFO_0006930, MONDO_0004975
Diseaseobsolete_red blood cell distribution width

AGO2 ATR TTC28 AVL9 SH3GL1 GATA6 EEF1A1P5 PLEKHG1 TBC1D14 HELZ2 DHX32 PKN2 CHST2 FTO SEC14L4

3.24e-03134714815EFO_0005192
Diseasetaste liking measurement

TUFM CD200R1 OR10A3 PPA2 PKHD1 OR10A6 FTO

3.53e-033881487EFO_0010155
DiseaseFEV/FEC ratio

BNC2 PSMA4 GATA6 GATA5 PTCH1 SEC14L3 THADA UBE2A HMCN1 ANAPC1 LTBP3 CHST2 FTO RPL5

3.60e-03122814814EFO_0004713
Diseasekidney volume

PTCH1 FTO

3.63e-03181482EFO_0600044
DiseaseMalignant neoplasm of endometrium

PMS1 ATR

3.63e-03181482C0007103
DiseaseMyeloid Leukemia

AGO2 SMC3

3.63e-03181482C0023470
DiseaseLeukemia, Monocytic, Chronic

AGO2 SMC3

3.63e-03181482C0023466
DiseaseCarcinoma in situ of endometrium

PMS1 ATR

3.63e-03181482C0346191
Diseasepuberty onset measurement

DLGAP1 IL20RB HERC2 FTO

3.68e-031251484EFO_0005677
Diseasemean arterial pressure

TCF20 INPP5A L2HGDH GRM7 PLEKHG1 THADA PKHD1 FTO

3.80e-034991488EFO_0006340
Diseasevital capacity

BNC2 STRN3 TCF20 GATA5 PTCH1 GRM7 TMEFF1 HMCN1 SUSD5 FER LRP2 LTBP3 FBN3 SAMD4A

3.81e-03123614814EFO_0004312
Diseaseurolithiasis

CD200R1 FTO ALPL

3.94e-03631483MONDO_0024647
DiseaseUlcerative Colitis

IKZF1 MST1 HERC2

3.94e-03631483C0009324
Diseasearterial stiffness measurement

BNC2 TCF20 SUSD5

4.12e-03641483EFO_0004517
Diseasepulmonary hypertension (is_marker_for)

GATA6 BIRC5 NOS2

4.12e-03641483DOID:6432 (is_marker_for)
DiseaseAstigmatism

BNC2 GRM7 CHD6 HERC2

4.12e-031291484HP_0000483
Diseasepulse pressure measurement

BNC2 TTC28 KDM5A INPP5A CRTAC1 SSPOP PLEKHG1 OTUD6B INTS11 FER CPXM1 PKN2 LTBP3 FTO SAMD4A

4.38e-03139214815EFO_0005763
DiseaseAdenocarcinoma of prostate

FOXA1 AR

4.47e-03201482C0007112
DiseaseStomach Carcinoma

ERBB2 ATR

4.93e-03211482C0699791

Protein segments in the cluster

PeptideGeneStartEntry
ERMAEAGFIHCPTEN

BIRC5

36

O15392
MPYGCLLDHVRENRG

ERBB2

801

P04626
CMHYTVRAPVGVAGL

ALDH8A1

136

Q9H2A2
MHPCNYRTAGEDTGV

ATG13

226

O75143
PGHGGIMDRFDCQYL

CDS1

391

Q92903
SFIPRYIGCNHMALE

CCDC33

371

Q8N5R6
YGAQHPMGLDVREDA

BNC2

921

Q6ZN30
LVSHVMACGGNTLYP

ACTL8

291

Q9H568
MCDANYAGGVVLHPR

ADAM2

286

Q99965
LEMHGDTCQPGIFNY

FAT4

4731

Q6V0I7
AVVGSMDAHPSRYCA

AGO1

611

Q9UL18
PEVRYVAGMHGNEAL

CPXM1

351

Q96SM3
DNLDGDMCIYHAPSG

DLGAP1

206

O14490
SPGYLEVMSACHQRA

ADCK5

116

Q3MIX3
NPNGKSEVCILHEYM

DGCR8

506

Q8WYQ5
IDIAGLGHCDFMNRP

DHX32

436

Q7L7V1
FLLAPGGHYCMDIDE

FBN3

561

Q75N90
QILGQFACMPEHRDY

CFLAR

291

O15519
GSMDAHPNRYCATVR

AGO2

616

Q9UKV8
ALYPMAQCHLSRVFG

ARHGEF39

276

Q8N4T4
DYNGNLPVHLAAMEG

ANKRD42

161

Q8N9B4
KHATGEAIYCDDMPL

AOX1

591

Q06278
GMCDHVSLALGQAGY

PRODH2

466

Q9UF12
DCGDLQHLPYQLMEV

NDST3

51

O95803
HRCPPGMDNVLDYGL

RGS9

191

O75916
CDYQGPRAVGMHSFL

HDHD3

196

Q9BSH5
IFADELHLGMGCPAN

OOSP2

46

Q86WS3
MCVHAYLSGQPLEES

ANAPC1

1866

Q9H1A4
MLLPCGVDQFHGTEY

APLP2

186

Q06481
PGHLYVCGDVRMARD

NOS2

1076

P35228
IPADGHCMYRAIQDQ

OTUD6A

146

Q7L8S5
GAMAYDRFAAICHPL

OR10A3

116

P58181
YCKHLGAEMDRLQPG

KMT2C

516

Q8NEZ4
LDHCGALPYFSEMVG

INTS11

71

Q5TA45
GLMAIDCPHTGIVDY

L2HGDH

181

Q9H9P8
NDYLGMSRHPRVCGA

ALAS1

251

P13196
RESMHAFCVGQYLEP

HERC2

1271

O95714
QVPYHKGNDVLCAAM

MAPK8IP1

576

Q9UQF2
AIPLHQGDCYFMLDD

FTO

286

Q9C0B1
QGPCVHMEAGVDYLS

C9orf131

901

Q5VYM1
VTYDHIGPNVCMGDH

INPP5A

371

Q14642
PRELCAFVSGAAAHM

C19orf85

16

A0A1B0GUS0
LGYEMVQVACGASHV

NEK8

441

Q86SG6
AGYHMECLDPPLQEV

PHRF1

206

Q9P1Y6
GMYRCGPASVQAIKH

F13A1

406

P00488
HDGYYRCIMVTPDGN

CD200R1

126

Q8TD46
LPGMEYVDGDFQCHT

IGFBP5

251

P24593
PYGMRLASNHLTCEG

LRP2

1001

P98164
HLSPGEQLRGDCMYA

AR

256

P10275
DCPGHADYVKNMITG

TUFM

126

P49411
EDGKCYTAMPGNTHR

RIC3

126

Q7Z5B4
ERCHNYLESMGLPGT

IKZF1

221

Q13422
ALEHGIPINMGYAVA

NDST4

406

Q9H3R1
HPDCGRAVQAVYEDM

DQX1

301

Q8TE96
MEHGVPVYRTNQCAG

KDM5A

546

P29375
HLETMEPGAAYCVKA

IL20RB

191

Q6UXL0
AFVQPGDAGHYTCMA

HMCN1

4136

Q96RW7
DRNYVLGAHPHGIMC

MOGAT3

106

Q86VF5
PHVMAYAACIGANLG

ALPL

481

P05186
EAGVNPEVCVLMHYG

ERVK-18

636

Q9QC07
LHPDSGNMFENGCYL

FOXA1

246

P55317
QIPSDGHCMYKAIED

OTUD6B

151

Q8N6M0
EPVCNACGLYMKLHG

GATA5

261

Q9BWX5
GEPVCNACGLYMKLH

GATA6

461

Q92908
SIYDCREMETNGPGH

ATR

1426

Q13535
EDMCNYRGLHDVLSP

BAMBI

101

Q13145
HLPENDRNYYGCGEM

B4GALT6

231

Q9UBX8
HGLNRTDCYIMNDPQ

CHD6

1591

Q8TD26
EQVERGYRMSAPQHC

FER

771

P16591
PGMIEHGLSDCSQYR

AVL9

226

Q8NBF6
ACPFYNHEQMGLLRD

DDX11L8

316

A8MPP1
DGSPIALFNMFIDHC

DNAH7

2451

Q8WXX0
GMAGGAVHIDYNCVP

DLD

376

P09622
CGHNYMPGQLTISDI

MACC1

391

Q6ZN28
YGIPAHRDIDECMLF

LTBP3

986

Q9NS15
GQISAGYAPVLDCHM

EEF1A1P5

351

Q5VTE0
NFCMGADPGLEHLLA

FOXS1

256

O43638
EAMCAYLNAGGHVDG

GEN1

136

Q17RS7
VLMCSVPGYDASGHV

DYNC1H1

4041

Q14204
YESMELACPAERSGH

KLHDC2

21

Q9Y2U9
CALAAAARGQEMYAP

GRM7

26

Q14831
SGYLCEMEPVAHFGL

CRTAC1

481

Q9NQ79
DIALELGTPYMCFHQ

DUS4L

266

O95620
LHPEECMYAVGQGAL

HMBS

206

P08397
ESGETGPCMEYLLHH

FHIP2A

71

Q5W0V3
GPLMDCRAFHYNVSS

MST1

61

P26927
RASYPCMSLHGGIDQ

DDX46

641

Q7L014
LDTQYRMHEGICAFP

HELZ2

2421

Q9BYK8
RYNAHMVPEDGNLTC

SEC14L3

341

Q9UDX4
RYNAHMVPEDGSLTC

SEC14L4

341

Q9UDX3
RYNAHMVPEDGILTC

SEC14L6

341

B5MCN3
EGMANCLPFYGVADL

PMS1

836

P54277
VEYAMEAIGHAGTCL

PSMA4

21

P25789
YNIFEGMECHGSPLV

CRMP1

431

Q14194
GGAQMYSHGIELACQ

CDC37L1

41

Q7L3B6
GAMAYDRFAAICHPL

OR10A6

116

Q8NH74
YVHLCPREDEMAADG

FSCN2

151

O14926
HPDSGNMFENGCYLR

FOXA2

236

Q9Y261
EHCEEYGRMLQADPN

RTCB

191

Q9Y3I0
CPVLGDHMYSARVGT

RPUSD3

256

Q6P087
MDYDRVGHNEIIGVC

SYT6

451

Q5T7P8
CKIIMAAYPAGHSVQ

TAS2R40

281

P59535
FDTFPQGLLHENCGM

UTP20

2311

O75691
FMLYAHGPDLCRESD

DROSHA

1021

Q9NRR4
VDPNGIYLMSGSHDC

STRN3

731

Q13033
DELLYVCAPGHIMGH

SUSD5

161

O60279
AAFPMYGRVHCITGA

THADA

916

Q6YHU6
GYHGIVMNNFECEPA

SMC3

531

Q9UQE7
MAPFARLHECYGQEI

PHETA1

221

Q8N4B1
MLFRSAEQCHQEGGP

SSPOP

2891

A2VEC9
PEMNCDGGHSYVRNY

LRRN3

651

Q9H3W5
QSGEQPYKMAGRCHA

NDUFS5

21

O43920
NEKCDHPAGGIHYEM

PTPN12

721

Q05209
HPAGGIHYEMCIECP

PTPN12

726

Q05209
AGNIEVGHGMICKAY

SMYD1

406

Q8NB12
PHVRYGAAMALGICC

PSMD1

646

Q99460
EVGHGYMDRPCLNPA

PTCH1

286

Q13635
CGSHVTYNMGLVLDP

SGPP1

331

Q9BX95
MDYFQIRHAEAGDCP

SATL1

526

Q86VE3
GDMIVCAAYAHELPK

RPL5

71

P46777
RQMGSCYPIQEDHGL

PKHD1

196

P08F94
APEGNLQHCLYSMSE

PKHD1

2161

P08F94
DYGVASQHNLPMDCL

IARS2

401

Q9NSE4
AMALYHTEERGQPCS

PPA2

31

Q9H2U2
DNQRHGMCLYLEPQG

PKN2

456

Q16513
GHDAPMIAYDAVLAA

ADPRH

271

P54922
AHIQQVGDRCYEEGM

CLTCL1

1196

P53675
PADYHALGAMEVICN

CHST2

386

Q9Y4C5
NLCIFQQGGPYHDML

TBC1D14

476

Q9P2M4
NMLIPSAARVHYGCV

SLC17A6

166

Q9P2U8
YPQSEGLLGECMIRH

SH3GL1

86

Q99961
MIGGHYTACARLPND

USP19

1161

O94966
VYQSMEILHCLGPDN

ERVK-9

61

P63127
QHMLVHSGERPYECG

ZNF865

241

P0CJ78
MHTSLPDIYAAGDIC

PYROXD1

346

Q8WU10
YCQAQGPVAAVLLMH

TBC1D10C

176

Q8IV04
GMARCPYDAKHANVA

SEMA6A

161

Q9H2E6
MCPVYDLDHNVEFNG

SIDT1

221

Q9NXL6
LGDACMVGAINPELY

SYT15B

171

X6R8R1
AIFDPRGHMIASCDA

SPAG16

526

Q8N0X2
PDRMYDLVAVVVHCG

USP12

296

O75317
MFHPNVYADGSICLD

UBE2A

76

P49459
QPLMETCHSVGAAYL

TNFRSF8

466

P28908
AGMYHCLAELPTGAA

SIGLEC1

1506

Q9BZZ2
TYHDPSAQEAGRCLM

TCF20

1151

Q9UGU0
VYQSMEILHCLGPDN

ERVK-10

61

P10265
QGCYELISGPMNRHA

UPK1B

216

O75841
NQVAEMLGHKYGVAC

WDR62

146

O43379
AYAGLGHAARCMQDL

TTC28

436

Q96AY4
PGECRAHGHLAAVYM

TTC28

791

Q96AY4
EIIHMGGNPYKCENV

ZNF66

556

Q6ZN08
ILEMDAIHHPGFCYS

PLEKHG1

431

Q9ULL1
SDQREDVYIGNHMPC

TMEFF1

261

Q8IYR6
VYQSMEILHCLGPDN

ERVK-8

61

P63122
YGVPCHLLNEMDAAN

USP40

496

Q9NVE5
QHQRIHTGEMPYECG

ZNF772

311

Q68DY9
QDKSMGCENGHVPLY

SAMD4A

206

Q9UPU9
MFHPNVYADGSICLD

UBE2B

76

P63146
AGYACMGAIFAGHLV

ZDHHC1

81

Q8WTX9
DLPGNSLRYMHYCEG

TMEM260

441

Q9NX78
NMFIPSAARVHYGCV

SLC17A8

171

Q8NDX2
GVLLYEMLCGHAPFE

PRKCH

541

P24723
DYNPLGDHVAGMLAV

LRRC73

181

Q5JTD7