Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionolfactory receptor activity

OR52P1 OR51B6 OR10H5 OR52D1

9.23e-05431124GO:0004984
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR52P1 OR51B6 OR10H5 OR52D1

1.42e-03884124GO:0004930
GeneOntologyBiologicalProcessdetection of stimulus

OR52P1 NOX3 OR51B6 OR10H5 OR52D1

5.28e-05722135GO:0051606
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR52P1 OR51B6 OR10H5 OR52D1

1.17e-04432134GO:0050911
GeneOntologyBiologicalProcesssensory perception of smell

OR52P1 OR51B6 OR10H5 OR52D1

1.55e-04465134GO:0007608
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR52P1 OR51B6 OR10H5 OR52D1

1.82e-04485134GO:0050907
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR52P1 OR51B6 OR10H5 OR52D1

2.45e-04524134GO:0009593
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR52P1 OR51B6 OR10H5 OR52D1

2.89e-04547134GO:0007606
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR52P1 OR51B6 OR10H5 OR52D1

3.66e-04582134GO:0050906
GeneOntologyBiologicalProcesshematopoietic stem cell differentiation

SH2B3 MLLT3

3.90e-0447132GO:0060218
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

OR52P1 SH2B3 OR51B6 OR10H5 OR52D1

1.14e-031395135GO:0007186
GeneOntologyBiologicalProcesssensory perception

OR52P1 OR51B6 OR10H5 OR52D1

3.56e-031072134GO:0007600
MousePhenoabnormal vestibuloocular reflex

LYST NOX3

1.29e-051082MP:0004844
DomainOlfact_rcpt

OR51B6 OR10H5 OR52D1

1.77e-03393123IPR000725
DomainGPCR_Rhodpsn_7TM

OR51B6 OR10H5 OR52D1

7.93e-03670123IPR017452
Domain7tm_1

OR51B6 OR10H5 OR52D1

8.16e-03677123PF00001
DomainG_PROTEIN_RECEP_F1_1

OR51B6 OR10H5 OR52D1

8.43e-03685123PS00237
DomainG_PROTEIN_RECEP_F1_2

OR51B6 OR10H5 OR52D1

8.64e-03691123PS50262
DomainGPCR_Rhodpsn

OR51B6 OR10H5 OR52D1

8.67e-03692123IPR000276
PathwayREACTOME_RAC3_GTPASE_CYCLE

NHS NOX3

1.50e-039392MM15609
PathwayREACTOME_RAC3_GTPASE_CYCLE

NHS NOX3

1.54e-039492M41818
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR51B6 OR10H5 OR52D1

1.55e-0338993M14091
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR51B6 OR10H5 OR52D1

1.89e-0341793M4072
Pubmed

Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters.

OR51B6 OR52D1

1.35e-051513211121057
Pubmed

Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes.

OR51B6 OR52D1

1.35e-051513210220430
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR52P1 OR51B6 OR52D1

2.46e-0434013311802173
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR52P1 OR51B6 OR52D1

2.46e-0434013311875048
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR52P1 OR51B6 OR52D1

2.53e-0434313332295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR52P1 OR51B6 OR52D1

2.59e-0434613314611657
Cytoband11p15.4

OR52P1 OR51B6 OR52D1

2.26e-0520013311p15.4
CytobandEnsembl 112 genes in cytogenetic band chr11p15

OR52P1 OR51B6 OR52D1

4.81e-04564133chr11p15
CytobandEnsembl 112 genes in cytogenetic band chr1q42

SIPA1L2 LYST

2.04e-03240132chr1q42
GeneFamilyOlfactory receptors, family 52

OR52P1 OR52D1

3.90e-0449112165
CoexpressionWOTTON_RUNX_TARGETS_DN

SIPA1L2 PXYLP1

9.15e-0529132MM558
CoexpressionWOTTON_RUNX_TARGETS_DN

SIPA1L2 PXYLP1

9.15e-0529132M4303
ToppCellControl-Epithelial-Club|Epithelial / Disease state, Lineage and Cell class

SIPA1L2 NHS MLLT3

1.90e-051851336814b3c94c7558443c038a227b5c8563d2cfeac4
DrugVerapamyl hydrochloride [152-11-4]; Down 200; 8.2uM; MCF7; HT_HG-U133A

SH2B3 LYST MLLT3

1.33e-041971235387_DN
DrugEthoxyquin [91-53-2]; Down 200; 18.4uM; MCF7; HT_HG-U133A

SH2B3 LYST MLLT3

1.35e-041981233421_DN
DrugBgs

LYST NHS

1.87e-0439122CID009549182
DrugMelphalan

LYST NHS MLLT3

3.57e-04276123ctd:D008558
Diseasedyslexia

SH2B3 NOX3

1.31e-03162102EFO_0005424
Diseaseneutrophil count, eosinophil count

SH2B3 PXYLP1

2.25e-03213102EFO_0004833, EFO_0004842
Diseaseneutrophil count, basophil count

SH2B3 PXYLP1

2.48e-03224102EFO_0004833, EFO_0005090
Diseasegranulocyte count

SH2B3 PXYLP1

3.17e-03254102EFO_0007987
Diseasehematocrit

SH2B3 MLLT3 PXYLP1

4.02e-031011103EFO_0004348
Diseasemonocyte count

SH2B3 LYST POLR3H

8.46e-031320103EFO_0005091

Protein segments in the cluster

PeptideGeneStartEntry
IKHHFKIHVPSQFFI

PRO1854

46

Q9UHT4
HFVEKVVFHLHESFP

MLLT3

46

P42568
HHHALHEAPKFTVET

BTBD11

336

A6QL63
HAVFHLPSHDAQHKA

OR52D1

226

Q9H346
SFLTHRFGHHEVPKH

OR52D1

261

Q9H346
RFGHHEVPKHVHIFL

OR52D1

266

Q9H346
HKEIHHFFCHVPPLL

OR10H5

171

Q8NGA6
LTFIHRFGKHVPHVV

OR51B6

256

Q9H340
FFTHRFGHHVPVHIH

OR52P1

261

Q8NH57
HLLHHFLTSFPKQDH

LYST

186

Q99698
PFHHRHPLHVFTHNK

NHS

1101

Q6T4R5
SHFQHVFVIVKVHNP

SIPA1L2

726

Q9P2F8
HAPHHFKLVSVHVFI

PXYLP1

81

Q8TE99
SHTKVHFRCVVFHPF

POLR3H

66

Q9Y535
THHVFIVFFLSLAIH

NOX3

206

Q9HBY0
FHQKPTLHIHERFHT

ZNF586

131

Q9NXT0
VQHLHFPSVVDMLHH

SH2B3

426

Q9UQQ2