Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	postsynapse	JAK2 APLP2 LRRTM1 ATP7A ZZEF1 ZNF804A PCLO UBE3B	8.91e-05	1018	31	8	GO:0098794
MousePheno	abnormal potassium level	ADAMTS16 CUL4A GAK NEDD1 ZZEF1 VWA8 ADCY6	1.89e-07	196	31	7	MP:0020887
MousePheno	abnormal potassium ion homeostasis	ADAMTS16 CUL4A GAK NEDD1 ZZEF1 VWA8 ADCY6	2.03e-07	198	31	7	MP:0011978
MousePheno	abnormal circulating potassium level	ADAMTS16 CUL4A GAK NEDD1 ZZEF1 VWA8	1.75e-06	171	31	6	MP:0002668
MousePheno	increased circulating potassium level	CUL4A GAK NEDD1 ZZEF1 VWA8	6.35e-06	121	31	5	MP:0005627
MousePheno	abnormal ion homeostasis	ADAMTS16 CUL4A JAK2 CACNA1D GAK ATP7A NEDD1 ZZEF1 VWA8 ADCY6 PLCL2	3.85e-05	1232	31	11	MP:0001765
MousePheno	increased coping response	ZNF521 HDAC4 ZZEF1	6.71e-05	36	31	3	MP:0003063
MousePheno	abnormal dendritic spine morphology	NEDD9 LRRTM1 ZNF804A UBE3B	1.15e-04	115	31	4	MP:0009936
MousePheno	decreased dendritic spine density	NEDD9 ZNF804A UBE3B	1.23e-04	44	31	3	MP:0020508
MousePheno	decreased depression-related behavior	ZNF521 HDAC4 ZZEF1	1.23e-04	44	31	3	MP:0014413
MousePheno	abnormal dendritic spine density	NEDD9 ZNF804A UBE3B	2.27e-04	54	31	3	MP:0020506
MousePheno	abnormal coping response	ZNF521 HDAC4 ZZEF1	4.11e-04	66	31	3	MP:0003062
MousePheno	abnormal hippocampus granule cell morphology	NEDD9 ZNF521	4.26e-04	14	31	2	MP:0009938
Domain	DUF4195	ZNF280D ZNF280C	1.60e-05	4	31	2	IPR025243
Domain	DUF4195	ZNF280D ZNF280C	1.60e-05	4	31	2	PF13836
Domain	zf-C2H2_jaz	ZNF622 ZNF804A	6.03e-04	22	31	2	PF12171
Domain	Znf_C2H2_jaz	ZNF622 ZNF804A	6.03e-04	22	31	2	IPR022755
Domain	Znf_C2H2-like	ZNF521 ZNF622 HIC1 ZNF280D ZNF804A ZNF280C	1.74e-03	796	31	6	IPR015880
Domain	Znf_C2H2	ZNF521 ZNF622 HIC1 ZNF280D ZNF804A ZNF280C	1.84e-03	805	31	6	IPR007087
Domain	ZnF_C2H2	ZNF521 ZNF622 HIC1 ZNF280D ZNF804A ZNF280C	1.87e-03	808	31	6	SM00355
Domain	C2_dom	GAK PCLO PLCL2	2.49e-03	164	31	3	IPR000008
Domain	SH3	NEDD9 PALS1 NEB	5.40e-03	216	31	3	PS50002
Domain	SH3	NEDD9 PALS1 NEB	5.40e-03	216	31	3	SM00326
Domain	SH3_domain	NEDD9 PALS1 NEB	5.68e-03	220	31	3	IPR001452
Domain	HEAT_REPEAT	PDS5B PDS5A	6.00e-03	70	31	2	PS50077
Domain	SH3_9	NEDD9 NEB	7.40e-03	78	31	2	PF14604
Domain	ZINC_FINGER_C2H2_2	ZNF521 HIC1 ZNF280D ZNF804A ZNF280C	8.42e-03	775	31	5	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF521 HIC1 ZNF280D ZNF804A ZNF280C	8.51e-03	777	31	5	PS00028
Pathway	KEGG_MEDICUS_REFERENCE_ESTABLISHMENT_OF_COHESION	PDS5B PDS5A	6.31e-05	7	25	2	M47869
Pathway	REACTOME_COHESIN_LOADING_ONTO_CHROMATIN	PDS5B PDS5A	1.35e-04	10	25	2	M27178
Pathway	REACTOME_COHESIN_LOADING_ONTO_CHROMATIN	PDS5B PDS5A	1.35e-04	10	25	2	MM14892
Pathway	REACTOME_ESTABLISHMENT_OF_SISTER_CHROMATID_COHESION	PDS5B PDS5A	1.64e-04	11	25	2	M27177
Pathway	REACTOME_ESTABLISHMENT_OF_SISTER_CHROMATID_COHESION	PDS5B PDS5A	1.64e-04	11	25	2	MM14891
Pathway	REACTOME_MITOTIC_TELOPHASE_CYTOKINESIS	PDS5B PDS5A	2.33e-04	13	25	2	M27661
Pathway	REACTOME_MITOTIC_TELOPHASE_CYTOKINESIS	PDS5B PDS5A	2.33e-04	13	25	2	MM15363
Pathway	REACTOME_CELL_CYCLE_MITOTIC	MASTL JAK2 PDS5B PDS5A NEDD1 POLA1	3.58e-04	561	25	6	M5336
Pathway	REACTOME_CELL_CYCLE	MASTL JAK2 PDS5B PDS5A NEDD1 POLA1	5.27e-04	603	25	6	MM14635
Pubmed	PDS5A and PDS5B in Cohesin Function and Human Disease.	PDS5B PDS5A	7.69e-07	2	31	2	34070827
Pubmed	PDS5A and PDS5B differentially affect gene expression without altering cohesin localization across the genome.	PDS5B PDS5A	7.69e-07	2	31	2	35986423
Pubmed	NEDD9 is transcriptionally regulated by HDAC4 and promotes breast cancer metastasis and macrophage M2 polarization via the FAK/NF-κB signaling pathway.	NEDD9 HDAC4	7.69e-07	2	31	2	39326322
Pubmed	PDS5 proteins are required for proper cohesin dynamics and participate in replication fork protection.	PDS5B PDS5A	7.69e-07	2	31	2	31757807
Pubmed	TRPV6 and Cav1.3 Mediate Distal Small Intestine Calcium Absorption Before Weaning.	CACNA1D TRPV6	2.31e-06	3	31	2	31398491
Pubmed	Pds5 Regulates Sister-Chromatid Cohesion and Chromosome Bi-orientation through a Conserved Protein Interaction Module.	PDS5B PDS5A	2.31e-06	3	31	2	28343969
Pubmed	Pds5B is required for cohesion establishment and Aurora B accumulation at centromeres.	PDS5B PDS5A	2.31e-06	3	31	2	24141881
Pubmed	Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.	CUL4A ZNF622 APLP2 WDR33 ZNF280C	2.74e-06	251	31	5	28077445
Pubmed	PDS5 proteins regulate the length of axial elements and telomere integrity during male mouse meiosis.	PDS5B PDS5A	4.61e-06	4	31	2	32285610
Pubmed	Topologically associating domains and chromatin loops depend on cohesin and are regulated by CTCF, WAPL, and PDS5 proteins.	PDS5B PDS5A	4.61e-06	4	31	2	29217591
Pubmed	DNA double-strand breaks lead to activation of hypermethylated in cancer 1 (HIC1) by SUMOylation to regulate DNA repair.	HIC1 HDAC4	7.68e-06	5	31	2	23417673
Pubmed	Sororin, a substrate of the anaphase-promoting complex, is required for sister chromatid cohesion in vertebrates.	PDS5B PDS5A	1.15e-05	6	31	2	15837422
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	MASTL PDS5B PDS5A ZNF280D POLA1 ZNF280C	1.41e-05	608	31	6	36089195
Pubmed	Functional contribution of Pds5 to cohesin-mediated cohesion in human cells and Xenopus egg extracts.	PDS5B PDS5A	1.61e-05	7	31	2	15855230
Pubmed	An acetylation/deacetylation-SUMOylation switch through a phylogenetically conserved psiKXEP motif in the tumor suppressor HIC1 regulates transcriptional repression activity.	HIC1 HDAC4	1.61e-05	7	31	2	17283066
Pubmed	Dosage effects of cohesin regulatory factor PDS5 on mammalian development: implications for cohesinopathies.	PDS5B PDS5A	1.61e-05	7	31	2	19412548
Pubmed	Genetic predictors of risk and resilience in psychiatric disorders: a cross-disorder genome-wide association study of functional impairment in major depressive disorder, bipolar disorder, and schizophrenia.	ADAMTS16 ZZEF1	2.15e-05	8	31	2	24039173
Pubmed	Distinct roles of cohesin-SA1 and cohesin-SA2 in 3D chromosome organization.	PDS5B PDS5A	2.15e-05	8	31	2	29867216
Pubmed	Quantitative analysis of cohesin complex stoichiometry and SMC3 modification-dependent protein interactions.	PDS5B PDS5A	2.15e-05	8	31	2	21699228
Pubmed	Sororin is required for stable binding of cohesin to chromatin and for sister chromatid cohesion in interphase.	PDS5B PDS5A	2.76e-05	9	31	2	17349791
Pubmed	Human Scc4 is required for cohesin binding to chromatin, sister-chromatid cohesion, and mitotic progression.	PDS5B PDS5A	2.76e-05	9	31	2	16682347
Pubmed	Human Wapl is a cohesin-binding protein that promotes sister-chromatid resolution in mitotic prophase.	PDS5B PDS5A	2.76e-05	9	31	2	17112726
Pubmed	Scc1 sumoylation by Mms21 promotes sister chromatid recombination through counteracting Wapl.	PDS5B PDS5A	3.44e-05	10	31	2	22751501
Pubmed	Phosphorylation-enabled binding of SGO1-PP2A to cohesin protects sororin and centromeric cohesion during mitosis.	PDS5B PDS5A	3.44e-05	10	31	2	23242214
Pubmed	Identification of a set of genes with developmentally down-regulated expression in the mouse brain.	NEDD9 NEDD1	3.44e-05	10	31	2	1378265
Pubmed	Sororin mediates sister chromatid cohesion by antagonizing Wapl.	PDS5B PDS5A	3.44e-05	10	31	2	21111234
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	JAK2 ZNF622 PDS5A ZZEF1 POLA1 PCLO	4.13e-05	736	31	6	29676528
Pubmed	Wapl controls the dynamic association of cohesin with chromatin.	PDS5B PDS5A	4.21e-05	11	31	2	17113138
Pubmed	APRIN is a cell cycle specific BRCA2-interacting protein required for genome integrity and a predictor of outcome after chemotherapy in breast cancer.	PDS5B PDS5A	4.21e-05	11	31	2	22293751
Pubmed	Inflammation-dependent overexpression of c-Myc enhances CRL4DCAF4 E3 ligase activity and promotes ubiquitination of ST7 in colitis-associated cancer.	CUL4A JAK2 HIC1 POLA1	7.83e-05	257	31	4	30945288
Pubmed	Aurora B and Cdk1 mediate Wapl activation and release of acetylated cohesin from chromosomes by phosphorylating Sororin.	PDS5B PDS5A	8.02e-05	15	31	2	23901111
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	CUL4A APLP2 HDAC4 NEDD1 ADCY6 UBE3B PLCL2	1.32e-04	1321	31	7	27173435
Pubmed	Dependence of Human Colorectal Cells Lacking the FBW7 Tumor Suppressor on the Spindle Assembly Checkpoint.	MASTL GAK LRRTM1	1.72e-04	121	31	3	26354767
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	PDS5B PDS5A APLP2 ZNF280D POLA1 PCLO ZNF280C	2.11e-04	1425	31	7	30948266
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	HDAC4 VWA8 PLCL2	2.12e-04	130	31	3	12421765
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	PDS5B PDS5A WDR33 POLA1	2.32e-04	341	31	4	32971831
Pubmed	Integrating genetic and network analysis to characterize genes related to mouse weight.	NEB VWA8	3.08e-04	29	31	2	16934000
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	ZNF521 PDS5B PDS5A APLP2 VWA8 WDR33	3.38e-04	1082	31	6	38697112
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	PDS5B ZNF622 PDS5A WDR33 POLA1	3.68e-04	704	31	5	29955894
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	PDS5B PALS1 APLP2 ATP7A NEDD1	4.05e-04	719	31	5	35337019
Pubmed	Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.	CACNA1D TRPV6	5.30e-04	38	31	2	30786075
Pubmed	The CRL4DCAF6 E3 ligase ubiquitinates CtBP1/2 to induce apoptotic signalling and promote intervertebral disc degeneration.	CUL4A TRPV6 ADCY6	7.37e-04	199	31	3	36688959
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	MASTL WDR33 POLA1 ZNF280C	7.88e-04	472	31	4	38943005
Pubmed	Identification of NPM-ALK interacting proteins by tandem mass spectrometry.	JAK2 GAK	8.11e-04	47	31	2	14968112
Pubmed	A cohesin-RAD21 interactome.	CUL4A PDS5B PDS5A	8.38e-04	208	31	3	22145905
Pubmed	Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.	ADAMTS16 NEDD9 NEDD1	8.61e-04	210	31	3	16537572
GeneFamily	PDZ domain containing	PALS1 PCLO	1.09e-02	152	19	2	1220
GeneFamily	WD repeat domain containing	NEDD1 WDR33	3.04e-02	262	19	2	362
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#5	NEDD9 PALS1 LRRTM1 NEB VWA8 POLA1 PCLO	3.51e-05	654	31	7	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K5
CoexpressionAtlas	FacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#4	NEDD9 ZNF521 LRRTM1 NEB ZZEF1 VWA8 PCLO	6.52e-05	721	31	7	Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_2500_K4
CoexpressionAtlas	FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_2500_k-means-cluster#3	NEDD9 ZNF521 LRRTM1 NEB ZZEF1 VWA8 PCLO	7.05e-05	730	31	7	Facebase_RNAseq_e8.5_Paraxial Mesoderm_2500_K3
CoexpressionAtlas	FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#2	NEDD9 ZNF521 LRRTM1 NEB ZZEF1 VWA8 PCLO	8.15e-05	747	31	7	Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_2500_K2
ToppCell	droplet-Limb_Muscle-nan-3m-Endothelial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIC1 ZZEF1 POLA1 ADCY6	8.69e-06	189	31	4	16a4c92dd7a0d60f3691bd3130a091a9a54730f1
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_1\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	ZNF521 LRRTM1 ZNF804A PCLO	8.87e-06	190	31	4	6e92c78799f34b31d098854503c796edb0dc7f80
ToppCell	COVID-19-kidney-CD-PC\|kidney / Disease (COVID-19 only), tissue and cell type	ADAMTS16 TRPV6 HDAC4 PLCL2	9.43e-06	193	31	4	738689d009e4b118d7ce3171a207294b95cbe78b
Drug	Cinchonine [118-10-5]; Down 200; 13.6uM; MCF7; HT_HG-U133A	CACNA1D NEB ZZEF1 ZNF804A WDR33 UBE3B	1.99e-07	191	31	6	2789_DN
Drug	Zuclopenthixol hydrochloride [633-59-0]; Down 200; 9.2uM; PC3; HT_HG-U133A	NEDD9 JAK2 PDS5A VWA8 ADCY6	6.85e-06	199	31	5	4261_DN
Drug	IAA-94	CACNA1D TRPV6 GAK	7.80e-05	61	31	3	CID000003667
Drug	Thiostrepton [1393-48-2]; Up 200; 2.4uM; HL60; HT_HG-U133A	PDS5A WDR33 ADCY6 UBE3B	1.10e-04	184	31	4	2462_UP
Drug	Dilazep dihydrochloride [20153-98-4]; Up 200; 6uM; PC3; HT_HG-U133A	NEDD9 NEB ADCY6 UBE3B	1.29e-04	192	31	4	7364_UP
Drug	Procaine hydrochloride [51-05-8]; Down 200; 14.6uM; MCF7; HT_HG-U133A	JAK2 PDS5B TRPV6 NEB	1.32e-04	193	31	4	5430_DN
Drug	calmidazolium chloride; Down 200; 5uM; MCF7; HT_HG-U133A_EA	JAK2 PDS5B VWA8 ADCY6	1.34e-04	194	31	4	906_DN
Drug	Salsolinol hydrobromide [38221-21-5]; Down 200; 15.4uM; MCF7; HT_HG-U133A	JAK2 CACNA1D NEB ZZEF1	1.37e-04	195	31	4	2791_DN
Drug	Sulfaguanidine [57-67-0]; Down 200; 18.6uM; PC3; HT_HG-U133A	PDS5B PDS5A VWA8 PCLO	1.40e-04	196	31	4	4257_DN
Drug	Methotrimeprazine maleat salt [7104-38-3]; Down 200; 9uM; MCF7; HT_HG-U133A	APLP2 HDAC4 ZZEF1 PCLO	1.40e-04	196	31	4	4723_DN
Drug	Mebhydroline 1,5-naphtalenedisulfonate [6153-33-9]; Up 200; 4.8uM; HL60; HT_HG-U133A	TRPV6 ZZEF1 WDR33 PLCL2	1.40e-04	196	31	4	1333_UP
Drug	5155877; Down 200; 10uM; MCF7; HT_HG-U133A	NEDD9 JAK2 NEB POLA1	1.42e-04	197	31	4	6549_DN
Drug	ionomycin calcium salt; Down 200; 2uM; MCF7; HT_HG-U133A_EA	JAK2 PDS5B PDS5A PALS1	1.42e-04	197	31	4	882_DN
Drug	Tiaprofenic acid [33005-95-7]; Down 200; 15.4uM; PC3; HT_HG-U133A	JAK2 NEB ZNF280D ADCY6	1.42e-04	197	31	4	4091_DN
Drug	Isocarboxazid [59-63-2]; Down 200; 17.2uM; PC3; HT_HG-U133A	NEDD9 JAK2 PDS5B VWA8	1.42e-04	197	31	4	7383_DN
Drug	Butylparaben [94-26-8]; Up 200; 20.6uM; MCF7; HT_HG-U133A	JAK2 CACNA1D WDR33 PLCL2	1.45e-04	198	31	4	6446_UP
Drug	SB 203580; Up 200; 1uM; MCF7; HT_HG-U133A	NEDD9 PDS5B PDS5A HDAC4	1.45e-04	198	31	4	6915_UP
Drug	Zalcitabine [7481-89-2]; Down 200; 19uM; PC3; HT_HG-U133A	JAK2 PDS5B PDS5A ADCY6	1.45e-04	198	31	4	4215_DN
Drug	Clenbuterol hydrochloride [21898-19-1]; Down 200; 12.8uM; MCF7; HT_HG-U133A	CACNA1D TRPV6 ZNF804A PCLO	1.45e-04	198	31	4	5266_DN
Drug	Alfaxalone [23930-19-0]; Down 200; 12uM; MCF7; HT_HG-U133A	JAK2 TRPV6 ZNF804A ADCY6	1.45e-04	198	31	4	5451_DN
Drug	Hemicholinium bromide [312-45-8]; Down 200; 7uM; HL60; HG-U133A	PDS5B GAK ZZEF1 PLCL2	1.45e-04	198	31	4	1601_DN
Drug	Betazole hydrochloride; Up 200; 27uM; MCF7; HT_HG-U133A	NEDD9 JAK2 CACNA1D TRPV6	1.45e-04	198	31	4	1690_UP
Drug	Calciferol [50-14-6]; Down 200; 10uM; MCF7; HT_HG-U133A	NEDD9 JAK2 CACNA1D ZNF280D	1.48e-04	199	31	4	5346_DN
Drug	Flucytosine [2022-85-7]; Down 200; 31uM; HL60; HT_HG-U133A	NEB WDR33 PCLO UBE3B	1.48e-04	199	31	4	3073_DN
Drug	Bephenium hydroxynaphthoate [3818-50-6]; Down 200; 9uM; PC3; HT_HG-U133A	JAK2 PDS5A TRPV6 VWA8	1.48e-04	199	31	4	4668_DN
Drug	Piribedil hydrochloride [78213-63-5]; Down 200; 12uM; PC3; HT_HG-U133A	NEDD9 JAK2 GAK VWA8	1.51e-04	200	31	4	6333_DN
Drug	Lymecycline [992-21-2]; Down 200; 6.6uM; PC3; HT_HG-U133A	NEDD9 JAK2 PDS5B HDAC4	1.51e-04	200	31	4	7291_DN
Disease	schizophrenia (implicated_via_orthology)	ZNF521 CACNA1D LRRTM1 ZNF804A	7.74e-07	68	31	4	DOID:5419 (implicated_via_orthology)
Disease	functional impairment measurement	ADAMTS16 ZZEF1	2.24e-05	7	31	2	EFO_0005412
Disease	urgency urinary incontinence	ADAMTS16 ZNF521	7.00e-05	12	31	2	EFO_0006865
Disease	Schizoaffective disorder-bipolar type	ZNF804A PCLO	1.27e-04	16	31	2	EFO_0009965
Disease	neurotic disorder	ZNF804A PCLO PLCL2	1.63e-04	101	31	3	EFO_0004257
Disease	anxiety measurement	TRPV6 ZNF804A PLCL2	1.99e-04	108	31	3	EFO_0009863
Disease	myeloproliferative disorder	ZNF521 JAK2	3.16e-04	25	31	2	EFO_0004251
Disease	internet addiction disorder	NEDD1 ZNF804A	5.53e-04	33	31	2	EFO_0803368
Disease	squamous cell lung carcinoma	MASTL PDS5B NEB	6.88e-04	165	31	3	EFO_0000708
Disease	wellbeing measurement	JAK2 ZNF804A PCLO UBE3B PLCL2	7.17e-04	692	31	5	EFO_0007869
Disease	Mood Disorders	CACNA1D HDAC4 ZNF804A	7.25e-04	168	31	3	C0525045
Disease	depressive symptom measurement	ZNF804A PCLO UBE3B PLCL2	9.90e-04	426	31	4	EFO_0007006
Disease	mean reticulocyte volume	CUL4A JAK2 PDS5B NEB PLCL2	1.36e-03	799	31	5	EFO_0010701
Disease	alcohol consumption measurement	ZNF521 CACNA1D ZNF280D ZNF804A PCLO UBE3B	1.64e-03	1242	31	6	EFO_0007878

Protein segments in the cluster

Peptide	Gene	Start	Entry
KNNIRFMNHMKHHLE	ZNF280D	331	Q6N043
ENIMKQNKMQLEHHQ	NEDD9	651	Q14511
LMEQMKHINEHSFNN	ADCY6	1066	O43306
KADMINKNMTHQVQA	MASTL	66	Q96GX5
VVVDKKMMQNHGHEN	ADAMTS16	296	Q8TE57
LHHNQNMSKEEMINL	ATP7A	681	Q04656
NNGHNQKVHMHMVDL	PDS5B	166	Q9NTI5
NNSHNKKVQMHMLDL	PDS5A	176	Q29RF7
HMNQMVFHKIRNEDL	JAK2	531	O60674
KAAQMKSQVMTHLHV	APLP2	521	Q06481
HIKQQQEMLAMKHQQ	HDAC4	111	P56524
VEMIKQFHMQLNEMH	NEDD1	616	Q8NHV4
QKQKQTMHQMAAMSA	LRRTM1	471	Q86UE6
AQQRNLISHMKMHAV	HIC1	601	Q14526
HQEQIIQMNGKTMHY	PCLO	4476	Q9Y6V0
AFSMKTMQNAKNHQN	POLA1	541	P09884
NAFKIHNAITVHMNK	PALS1	161	Q8N3R9
QAKMASMKMFQIQFH	GAK	656	O14976
SKDIMVHFKQHMQNQ	CUL4A	501	Q13619
MMKKMQHQRQQQADH	CACNA1D	6	Q01668
NHCSIKQQKVMVQHM	PLCL2	521	Q9UPR0
LMNHMEQVHSGEKKN	ZNF521	296	Q96K83
GNTVMFQHLMQKRKH	TRPV6	291	Q9H1D0
HLMAHFRMHTQIKNQ	UBE3B	881	Q7Z3V4
NHLFTMMNVTEQEHK	ZZEF1	876	O43149
MKNNATKQMHFRVQV	ZNF622	461	Q969S3
KNNIRFMNHMKHHLE	ZNF280C	326	Q8ND82
NMNNVKMFQAHKEAI	WDR33	191	Q9C0J8
SHKQLQAEMMQSHMV	VWA8	426	A3KMH1
LQNDMKHMSQNQAVK	ZNF804A	741	Q7Z570
DMVLAKQNAHTMNKH	NEB	2221	P20929