Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	glycogen synthase activity, transferring glucose-1-phosphate	GYS1 GYS2	7.45e-06	2	55	2	GO:0061547
GeneOntologyMolecularFunction	alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity	GYS1 GYS2	2.23e-05	3	55	2	GO:0004373
MousePheno	conical molar	FAM20C FAM20A	8.39e-06	2	41	2	MP:0030500
MousePheno	conical tooth	FAM20C FAM20A	8.39e-06	2	41	2	MP:0030499
Domain	TIL	FCGBP MUC5B MUC2	4.93e-06	12	54	3	PF01826
Domain	C8	FCGBP MUC5B MUC2	4.93e-06	12	54	3	PF08742
Domain	Unchr_dom_Cys-rich	FCGBP MUC5B MUC2	6.40e-06	13	54	3	IPR014853
Domain	C8	FCGBP MUC5B MUC2	6.40e-06	13	54	3	SM00832
Domain	TIL_dom	FCGBP MUC5B MUC2	8.13e-06	14	54	3	IPR002919
Domain	Glycogen_synth	GYS1 GYS2	8.21e-06	2	54	2	IPR008631
Domain	Glycogen_syn	GYS1 GYS2	8.21e-06	2	54	2	PF05693
Domain	VWD	FCGBP MUC5B MUC2	1.25e-05	16	54	3	SM00216
Domain	VWF_type-D	FCGBP MUC5B MUC2	1.25e-05	16	54	3	IPR001846
Domain	VWFD	FCGBP MUC5B MUC2	1.25e-05	16	54	3	PS51233
Domain	VWD	FCGBP MUC5B MUC2	1.25e-05	16	54	3	PF00094
Domain	VWC_out	FCGBP MUC5B MUC2	2.14e-05	19	54	3	SM00215
Domain	FAM20	FAM20C FAM20A	2.46e-05	3	54	2	IPR024869
Domain	FAM20_C	FAM20C FAM20A	2.46e-05	3	54	2	IPR009581
Domain	Fam20C	FAM20C FAM20A	2.46e-05	3	54	2	PF06702
Domain	WxxW_domain	MUC5B MUC2	1.22e-04	6	54	2	IPR025155
Domain	Mucin2_WxxW	MUC5B MUC2	1.22e-04	6	54	2	PF13330
Domain	VWC	FCGBP MUC5B MUC2	1.79e-04	38	54	3	SM00214
Domain	VWF_dom	FCGBP MUC5B MUC2	2.42e-04	42	54	3	IPR001007
Domain	CTCK_1	MUC5B MUC2	1.22e-03	18	54	2	PS01185
Domain	CARBOXYPEPT_ZN_2	CPA4 AGBL2	1.36e-03	19	54	2	PS00133
Domain	CARBOXYPEPT_ZN_1	CPA4 AGBL2	1.51e-03	20	54	2	PS00132
Domain	CT	MUC5B MUC2	1.83e-03	22	54	2	SM00041
Domain	Peptidase_M14	CPA4 AGBL2	2.00e-03	23	54	2	PF00246
Domain	Peptidase_M14	CPA4 AGBL2	2.00e-03	23	54	2	IPR000834
Domain	Cys_knot_C	MUC5B MUC2	2.36e-03	25	54	2	IPR006207
Domain	CTCK_2	MUC5B MUC2	2.36e-03	25	54	2	PS01225
Domain	VWFC_1	MUC5B MUC2	4.85e-03	36	54	2	PS01208
Domain	VWFC_2	MUC5B MUC2	5.40e-03	38	54	2	PS50184
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	SEMA4D MTMR7 LATS1 LLGL1 PLA2G4B CSNK2A1 CAPN6 USP24 MMP11 PPWD1	1.95e-07	730	55	10	34857952
Pubmed	Overexpression of CDC14B causes mitotic arrest and inhibits zygotic genome activation in mouse preimplantation embryos.	CDC14C CDC14B	2.46e-06	2	55	2	19923902
Pubmed	The Cdc14B phosphatase displays oncogenic activity mediated by the Ras-Mek signaling pathway.	CDC14C CDC14B	2.46e-06	2	55	2	21502810
Pubmed	The IgGFc-binding protein FCGBP is secreted with all GDPH sequences cleaved but maintained by interfragment disulfide bonds.	FCGBP MUC2	2.46e-06	2	55	2	34126068
Pubmed	Proteomic analyses of the two mucus layers of the colon barrier reveal that their main component, the Muc2 mucin, is strongly bound to the Fcgbp protein.	FCGBP MUC2	2.46e-06	2	55	2	19432394
Pubmed	[Interleukin-1beta induces MUC2/MUC5B gene expression in human nasal epithelial cells].	MUC5B MUC2	2.46e-06	2	55	2	20873538
Pubmed	Birth and rapid subcellular adaptation of a hominoid-specific CDC14 protein.	CDC14C CDC14B	2.46e-06	2	55	2	18547142
Pubmed	Whole-Exome sequencing identifies FAM20A mutations as a cause of amelogenesis imperfecta and gingival hyperplasia syndrome.	FAM20C FAM20A	7.36e-06	3	55	2	21549343
Pubmed	Early-onset aging and defective DNA damage response in Cdc14b-deficient mice.	CDC14C CDC14B	7.36e-06	3	55	2	21262768
Pubmed	The Raine syndrome protein FAM20C is a Golgi kinase that phosphorylates bio-mineralization proteins.	FAM20C FAM20A	7.36e-06	3	55	2	22900076
Pubmed	Cdc14b regulates mammalian RNA polymerase II and represses cell cycle transcription.	CDC14C CDC14B	7.36e-06	3	55	2	22355704
Pubmed	CDC14B acts through FZR1 (CDH1) to prevent meiotic maturation of mouse oocytes.	CDC14C CDC14B	7.36e-06	3	55	2	19129509
Pubmed	FAM20: an evolutionarily conserved family of secreted proteins expressed in hematopoietic cells.	FAM20C FAM20A	7.36e-06	3	55	2	15676076
Pubmed	Phosphate groups as substrate determinants for casein kinase I action.	CSNK2A1 GYS1	7.36e-06	3	55	2	2117608
Pubmed	Amelogenesis imperfecta and other biomineralization defects in Fam20a and Fam20c null mice.	FAM20C FAM20A	7.36e-06	3	55	2	22732358
Pubmed	Mucin gene polymorphisms in otitis media patients.	MUC5B MUC2	7.36e-06	3	55	2	19718741
Pubmed	Cdc14A and Cdc14B Redundantly Regulate DNA Double-Strand Break Repair.	CDC14C CDC14B	7.36e-06	3	55	2	26283732
Pubmed	Polymorphisms in MUC1, MUC2, MUC5B and MUC6 genes are not associated with the risk of chronic atrophic gastritis.	MUC5B MUC2	1.47e-05	4	55	2	21596555
Pubmed	Expression of human TFF3 in relation to growth of HT-29 cell subpopulations: involvement of PI3-K but not STAT6.	PIK3CG MUC2	1.47e-05	4	55	2	15733066
Pubmed	Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.	MUC5B MUC2	1.47e-05	4	55	2	23807779
Pubmed	CDC14A phosphatase is essential for hearing and male fertility in mouse and human.	CDC14C CDC14B	1.47e-05	4	55	2	29293958
Pubmed	Increased expression of MUC5AC and MUC5B promoting bacterial biofilm formation in chronic rhinosinusitis patients.	MUC5B MUC2	1.47e-05	4	55	2	25638393
Pubmed	Transcriptional Responses in the Murine Spleen after Toxoplasma gondii Infection: Inflammasome and Mucus-Associated Genes.	FCGBP MUC2	1.47e-05	4	55	2	28604600
Pubmed	Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.	MUC5B MUC2	1.47e-05	4	55	2	17471237
Pubmed	Expression of MUC1, MUC2, MUC5AC and MUC5B in mucinous lesions of the breast.	MUC5B MUC2	1.47e-05	4	55	2	22269464
Pubmed	The mouse secreted gel-forming mucin gene cluster.	MUC5B MUC2	1.47e-05	4	55	2	14984930
Pubmed	Characterization of mouse muc6 and evidence of conservation of the gel-forming mucin gene cluster between human and mouse.	MUC5B MUC2	1.47e-05	4	55	2	12676567
Pubmed	Effects of the Helicobacter pylori Virulence Factor CagA and Ammonium Ion on Mucins in AGS Cells.	MUC5B MUC2	1.47e-05	4	55	2	29869461
Pubmed	Mis12 controls cyclin B1 stabilization via Cdc14B-mediated APC/CCdh1 regulation during meiotic G2/M transition in mouse oocytes.	CDC14C CDC14B	1.47e-05	4	55	2	32341029
Pubmed	Polymorphism of human mucin genes in chest disease: possible significance of MUC2.	MUC5B MUC2	2.45e-05	5	55	2	11062147
Pubmed	Differential expression of MUC genes in endometrial and cervical tissues and tumors.	MUC5B MUC2	2.45e-05	5	55	2	16188033
Pubmed	Comprehensive glycomics comparison between colon cancer cell cultures and tumours: implications for biomarker studies.	MUC5B MUC2	2.45e-05	5	55	2	24840470
Pubmed	Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.	MUC5B MUC2	3.67e-05	6	55	2	19110483
Pubmed	Identification of glycogen synthase as a new substrate for stress-activated protein kinase 2b/p38beta.	GYS1 GYS2	3.67e-05	6	55	2	14680475
Pubmed	Hepatic glycogen synthesis in the absence of glucokinase: the case of embryonic liver.	GYS1 GYS2	5.13e-05	7	55	2	18165236
Pubmed	A secretory kinase complex regulates extracellular protein phosphorylation.	FAM20C FAM20A	6.83e-05	8	55	2	25789606
Pubmed	Secreted kinase phosphorylates extracellular proteins that regulate biomineralization.	FAM20C FAM20A	6.83e-05	8	55	2	22582013
Pubmed	PMEPA1 isoform a drives progression of glioblastoma by promoting protein degradation of the Hippo pathway kinase LATS1.	LATS1 DHX9	8.78e-05	9	55	2	31605013
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	CPA4 CSNK2A1 GYS1 USP24 XXYLT1 NAA40 TMX3 CLUH DHX9	1.84e-04	1297	55	9	33545068
Pubmed	Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice.	ASH1L DHX9	2.90e-04	16	55	2	16096065
Pubmed	Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.	MUC5B MUC2	3.70e-04	18	55	2	18834073
Pubmed	Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci.	SEMA4D CADM1	4.58e-04	20	55	2	22863734
Pubmed	WWP2-WWP1 ubiquitin ligase complex coordinated by PPM1G maintains the balance between cellular p73 and ΔNp73 levels.	GYS1 USP24 DHX9	4.97e-04	97	55	3	25071155
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	CADM1 SLC22A16 ARHGAP26 GYS1 USP24 IFIT1	5.03e-04	638	55	6	31182584
Pubmed	The imprinted Phlda2 gene regulates extraembryonic energy stores.	GYS1 GYS2	5.56e-04	22	55	2	19884348
Pubmed	Centrosome-related genes, genetic variation, and risk of breast cancer.	LATS1 PIK3CG CSNK2A1	5.75e-04	102	55	3	20508983
Pubmed	Large tumor suppressor homologs 1 and 2 regulate mouse liver progenitor cell proliferation and maturation through antagonism of the coactivators YAP and TAZ.	LATS1 GYS2	6.08e-04	23	55	2	27531557
Pubmed	Sequential phases of cortical specification involve Neurogenin-dependent and -independent pathways.	SLC22A16 NR2E1	6.08e-04	23	55	2	15229646
Pubmed	Distinct roles of androgen receptor, estrogen receptor alpha, and BCL6 in the establishment of sex-biased DNA methylation in mouse liver.	FMO2 ALDH3B1	6.63e-04	24	55	2	34215813
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	CADM1 PIK3CG GYS2 HPF1 USP24 XXYLT1 DCDC2B ALDH3B1	7.09e-04	1242	55	8	30973865
Pubmed	HIV-1 Tat protein down-regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3-kinase/AKT/cyclic nucleoside phosphodiesterase pathway.	PIK3CG PDE10A	8.40e-04	27	55	2	11156964
Pubmed	Physiogenomic comparison of edema and BMI in patients receiving rosiglitazone or pioglitazone.	PIK3CG GYS1 GYS2	8.57e-04	117	55	3	18996102
Pubmed	Characterising the dynamics of placental glycogen stores in the mouse.	GYS1 GYS2	9.70e-04	29	55	2	32798765
Pubmed	Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives.	CDC14C CADM1 CSNK2A1 CDC14B	1.41e-03	306	55	4	18973680
Pubmed	Analysis of phosphatase and tensin homolog tumor suppressor interacting proteins by in vitro and in silico proteomics.	CSNK2A1 ARHGAP26	1.49e-03	36	55	2	15717329
Cytoband	4q33	HPF1 ANXA10	6.30e-05	10	55	2	4q33
Cytoband	7p12.3	CDC14C PKD1L1	3.21e-04	22	55	2	7p12.3
Cytoband	Ensembl 112 genes in cytogenetic band chr7p12	CDC14C PKD1L1	2.63e-03	63	55	2	chr7p12
GeneFamily	Glycosyl transferases group 1 domain containing	GYS1 GYS2	1.92e-04	10	38	2	427
GeneFamily	CD molecules\|Mucins	MUC5B MUC2	8.81e-04	21	38	2	648
Coexpression	NABA_ECM_AFFILIATED	LMAN1L SEMA4D ANXA10 MUC5B MUC2	2.04e-05	158	55	5	MM17063
Coexpression	NABA_MATRISOME_ASSOCIATED	LMAN1L SEMA4D FAM20C PAMR1 ANXA10 MUC5B MMP11 FAM20A MUC2	2.11e-05	738	55	9	MM17058
Coexpression	NABA_MATRISOME_ASSOCIATED	LMAN1L SEMA4D FAM20C PAMR1 ANXA10 MUC5B MMP11 FAM20A MUC2	2.42e-05	751	55	9	M5885
Coexpression	NABA_ECM_AFFILIATED	LMAN1L SEMA4D ANXA10 MUC5B MUC2	2.90e-05	170	55	5	M5880
ToppCell	(03)_Secretory-(0)_uninjured\|(03)_Secretory / shred by cell type and Timepoint	FMO2 FCGBP CADM1 MUC5B ALDH3B1	2.43e-06	174	55	5	ebdddb5091afcc49ab533c890f260f709880c5f9
ToppCell	Control-Epithelial_cells-Airway_mucous\|Control / group, cell type (main and fine annotations)	FCGBP STS ARHGAP26 ANXA10 MUC5B	3.11e-06	183	55	5	15d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCell	-Unknown-Endothelial-Myofibroblast\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LATS1 CSNK2A1 USP24 PPWD1 IFIT1	3.55e-06	188	55	5	6468fa95ad0395395301115286f2d8c0df5d3882
ToppCell	-Unknown-Endothelial\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LATS1 CSNK2A1 USP24 PPWD1 IFIT1	3.55e-06	188	55	5	7a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell	-Unknown\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LATS1 CSNK2A1 USP24 PPWD1 IFIT1	3.55e-06	188	55	5	9cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCell	Enterocyte_Progenitors-C_06\|Enterocyte_Progenitors / shred on cell type and cluster	FCGBP CADM1 CAPN6 ANXA10 MUC5B	3.93e-06	192	55	5	b9938e1a929c00628cc6ebfdf10cf285167f445c
ToppCell	(02)_Cycling_Basal_(regeneration)-(3)_72hpi\|(02)_Cycling_Basal_(regeneration) / shred by cell type and Timepoint	PKD1L1 ANXA10 MUC5B IFIT1	2.21e-05	133	55	4	32c6a00671af309c4b0b90e93549733729684c61
ToppCell	lung-Club_Cells\|lung / shred on tissue and cell subclass	SEMA4D FMO2 FCGBP MUC2	5.02e-05	164	55	4	b12cacd499b18b96120ca6d14646aebeaed41d10
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|356C / Donor, Lineage, Cell class and subclass (all cells)	ARHGAP26 USP24 CDKL3 NAA40	5.26e-05	166	55	4	c4f7ea1cad962b1d6ad77423d15978b68a0d6f1d
ToppCell	facs-Lung-24m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l14\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FAM20C LLGL1 GYS1 CLUH	5.64e-05	169	55	4	813472d429c0b12580b17b440e00a6d8beb7947f
ToppCell	356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	FMO2 FCGBP MUC5B MMP11	6.75e-05	177	55	4	709235694cc711b9b79690e23c94577b2ae06811
ToppCell	Adult-Epithelial-club_cell-D175\|Adult / Lineage, Cell type, age group and donor	FMO2 SLC45A2 FAM20A CDC14B	6.75e-05	177	55	4	d652b7d84fe6aa38319d8d5adc72c70441bd0088
ToppCell	5'-Adult-Distal_Rectal-Epithelial-goblet-Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RANBP17 FCGBP DCDC2B MUC2	6.75e-05	177	55	4	e1e45956887371b1c18f1eb479dd930031497520
ToppCell	356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	FMO2 FCGBP MUC5B MMP11	6.75e-05	177	55	4	7f9c2a45a994b32f15e5693f7cb873716a4eb568
ToppCell	5'-Adult-Distal_Rectal-Epithelial-goblet\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FCGBP DCDC2B MUC5B MUC2	6.90e-05	178	55	4	9099b47e0756d6a1b7ba1c6aa7b47c5425f649e0
ToppCell	nucseq-Epithelial-Epithelial_Glandular\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FCGBP STS ANXA10 MUC5B	7.05e-05	179	55	4	859cd8ee414ad6207c046ada2e655e49322dd01c
ToppCell	nucseq-Epithelial-Epithelial_Glandular-Goblet\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FCGBP STS ANXA10 MUC5B	7.21e-05	180	55	4	3dc80bc636bf0e6ffc9762853132a9fe59fd1f66
ToppCell	nucseq-Epithelial-Epithelial_Glandular-Goblet-Goblet\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FCGBP STS ANXA10 MUC5B	7.21e-05	180	55	4	668a2d8e1d5a390309d5eb62c836f5903144bea9
ToppCell	BAL-Control-Epithelial-Epithelial-Basal/Club\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CPA4 FMO2 MUC5B PDE10A	7.36e-05	181	55	4	faff2a34e391d053a17c926540e6cb46d94dd629
ToppCell	BAL-Control-Epithelial-Epithelial-Basal/Club\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CPA4 FMO2 MUC5B PDE10A	7.36e-05	181	55	4	58651853f9c715075889856793df66ebe00c04f1
ToppCell	BAL-Control-Epithelial-Epithelial-Basal/Club-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CPA4 FMO2 MUC5B PDE10A	7.36e-05	181	55	4	5a9c332c0bf07cc20eaf8cf77b45e73668a6467d
ToppCell	BAL-Control-Epithelial-Epithelial-Basal/Club-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CPA4 FMO2 MUC5B PDE10A	7.36e-05	181	55	4	488a517f6e5543b648a2e72e0e04332fad776de6
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FMO2 FCGBP MUC5B PDE10A	7.52e-05	182	55	4	3f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCell	Control-Epithelial_cells-Airway_goblet\|Control / group, cell type (main and fine annotations)	FCGBP STS ANXA10 MUC5B	7.85e-05	184	55	4	d92a71441e4e19f8c301999d8186f8e48e3cd162
ToppCell	10x5'-GI_large-bowel-Myeloid_Monocytic\|GI_large-bowel / Manually curated celltypes from each tissue	FAM20C FCGBP ALDH3B1 FAM20A	8.52e-05	188	55	4	d0045fdda757d191dabc7853f6a6e99c0e97d93d
ToppCell	10x5'-GI_large-bowel-Myeloid_Monocytic-Classical_monocytes\|GI_large-bowel / Manually curated celltypes from each tissue	FAM20C FCGBP ALDH3B1 FAM20A	8.52e-05	188	55	4	0bcf04aa47738f43c1a87dae5dc487738ee86f8c
ToppCell	3'-Adult-Distal_Rectal-Epithelial-goblet-Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FCGBP XXYLT1 PEX2 MUC2	8.70e-05	189	55	4	7dad62bd50c197838058e89abd0ee387de3e83cd
ToppCell	10x5'v1-week_14-16-Myeloid_macrophage-stroma-erythroid_macrophage\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	FAM20C FCGBP CADM1 IFIT1	8.88e-05	190	55	4	cf463b2f227f3cc7d3fd296c810c0cbe51cbee72
ToppCell	IPF-Epithelial-Goblet\|Epithelial / Disease state, Lineage and Cell class	FMO2 ARHGAP26 MUC5B PDE10A	9.06e-05	191	55	4	267e1192aaec468c1a59eb24848b37e0e18cbc44
ToppCell	IPF-Epithelial-Club\|Epithelial / Disease state, Lineage and Cell class	RANBP17 FMO2 CADM1 FAM20A	9.25e-05	192	55	4	356e7a820b744a0ac87352a8d0e6e8d9fa9ed7d2
ToppCell	facs-Lung-EPCAM-18m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO2 PAMR1 MMP11 FAM20A	9.25e-05	192	55	4	5876ff75e273a48e7ad8236423fb41e4ae4c0a91
ToppCell	COPD-Epithelial-Goblet\|Epithelial / Disease state, Lineage and Cell class	FCGBP ARHGAP26 MUC5B PDE10A	9.62e-05	194	55	4	72a2e0cba171ab59aa176e91a59a54c562af0390
ToppCell	C_06\|World / shred on cell type and cluster	CADM1 CAPN6 ANXA10 MUC5B	9.62e-05	194	55	4	5cb42e09f380c4468cdc603ec0c3de35eadd3213
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.2.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CADM1 CAPN6 ANXA10 FAM20A	1.00e-04	196	55	4	784459f9f3614ead947aeb61a873dfd4cbe50641
ToppCell	distal-Epithelial-Alveolar_Epithelial_Type_1-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	RANBP17 FMO2 CADM1 FAM20A	1.06e-04	199	55	4	c1daa481f88d5281b6b5ea8ec8bb70cc0907d613
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Neuroepithelial-Proteoglycan-expressing_cell\|10w / Sample Type, Dataset, Time_group, and Cell type.	CPA4 FMO2 SLC45A2 MMP11	1.08e-04	200	55	4	07d2133c85e0a4eb8bef653ee15ecd0f1b2bbd44
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FMO2 FCGBP MUC5B PDE10A	1.08e-04	200	55	4	b992eeddee38e6fe3564e9b1850f6b20b89bf47d
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Neuroepithelial\|10w / Sample Type, Dataset, Time_group, and Cell type.	CPA4 FMO2 SLC45A2 MMP11	1.08e-04	200	55	4	ff0b2675c68e9fc1fa16b3276431f199f3642eac
Drug	F-6b	CSNK2A1 GYS1 GYS2	7.31e-06	16	55	3	CID000004288
Drug	Pancuronium bromide [15500-66-0]; Up 200; 5.4uM; PC3; HT_HG-U133A	SEMA4D STS ARHGAP26 CDKL3 MMP11 CDC14B	7.92e-06	197	55	6	4570_UP
Drug	Adrenosterone [382-45-6]; Down 200; 13.4uM; PC3; HT_HG-U133A	LATS1 CADM1 STS USP24 ANXA10 CDC14B	8.39e-06	199	55	6	5045_DN
Drug	v 405	GYS1 GYS2	1.72e-05	3	55	2	CID003057126
Drug	ST-281	CADM1 STS	1.72e-05	3	55	2	CID000156393
Drug	nicotine iminium	GYS1 GYS2	1.72e-05	3	55	2	CID000000431
Drug	1-o-phosphonohex-2-ulose	GYS1 GYS2 DHX9	4.66e-05	29	55	3	CID000000481
Drug	m-anisidine	GYS1 GYS2	5.70e-05	5	55	2	CID000010824
Drug	Pro-Leu-Ser-Arg-Thr-Leu-Ser-Val-Ala-Ala-Lys-Lys	GYS1 GYS2	8.54e-05	6	55	2	CID003277749
Drug	phenyl glucuronide	GYS1 GYS2	8.54e-05	6	55	2	CID000087235
Drug	5-chloro-indole-2-carboxylic acid	GYS1 GYS2	8.54e-05	6	55	2	CID000082693
Drug	hexanediamine	GYS1 GYS2	8.54e-05	6	55	2	CID000134940
Drug	AC1L196J	GYS1 GYS2	8.54e-05	6	55	2	CID000000415
Drug	BAY R3401	GYS1 GYS2	8.54e-05	6	55	2	CID009842599
Drug	Diltiazem hydrochloride [33286-22-5]; Up 200; 8.8uM; PC3; HT_HG-U133A	MTMR7 LLGL1 ARHGAP26 PDE10A MUC2	1.05e-04	194	55	5	6710_UP
Drug	Ethotoin [86-35-1]; Up 200; 19.6uM; MCF7; HT_HG-U133A	STS ARHGAP26 MUC5B PDE10A MUC2	1.08e-04	195	55	5	6052_UP
Drug	Medrysone [2668-66-8]; Up 200; 11.6uM; MCF7; HT_HG-U133A	LLGL1 STS ARHGAP26 SLC45A2 MUC5B	1.13e-04	197	55	5	4727_UP
Drug	Dihydroergotoxine mesylate [8067-24-1]; Up 200; 6.4uM; MCF7; HT_HG-U133A	STS PAMR1 PDE10A IFIT1 CDC14B	1.13e-04	197	55	5	4152_UP
Drug	Niacin [59-67-6]; Up 200; 32.4uM; MCF7; HT_HG-U133A	LLGL1 STS SLC45A2 PDE10A MMP11	1.16e-04	198	55	5	3381_UP
Drug	PHA-00745360 [351320-33-7]; Down 200; 1uM; PC3; HT_HG-U133A	LATS1 CADM1 STS CDKL3 CDC14B	1.18e-04	199	55	5	4562_DN
Drug	Griseofulvin [126-07-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A	STS ARHGAP26 MMP11 IFIT1 CDC14B	1.18e-04	199	55	5	4687_UP
Drug	Tiapride hydrochloride [51012-33-0]; Up 200; 11uM; MCF7; HT_HG-U133A	LLGL1 STS PAMR1 SLC45A2 MMP11	1.18e-04	199	55	5	2292_UP
Drug	Gentamicine sulfate [1405-41-0]; Down 200; 2.6uM; MCF7; HT_HG-U133A	RANBP17 SEMA4D CADM1 CDKL3 CDC14B	1.18e-04	199	55	5	7237_DN
Drug	Chloropeptide	GYS1 GYS2	1.19e-04	7	55	2	CID000025565
Drug	NSC106398	GYS1 GYS2	1.19e-04	7	55	2	CID000086763
Drug	Sulfamethazine sodium salt [1981-58-4]; Up 200; 13.4uM; PC3; HT_HG-U133A	SEMA4D CAPN6 PDE10A MMP11 CDC14B	1.21e-04	200	55	5	3765_UP
Disease	Lafora disease (implicated_via_orthology)	GYS1 GYS2	1.89e-05	4	53	2	DOID:3534 (implicated_via_orthology)
Disease	kidney cancer (implicated_via_orthology)	LATS1 LLGL1	1.72e-04	11	53	2	DOID:263 (implicated_via_orthology)
Disease	Bipolar I disorder	SLC22A16 NR2E1	1.72e-04	11	53	2	C0853193
Disease	hematocrit	SEMA4D LLGL1 ARHGAP26 GYS2 ASH1L XXYLT1 PDE10A ZFYVE1	4.17e-04	1011	53	8	EFO_0004348
Disease	brain cancer (implicated_via_orthology)	LLGL1 NR2E1	1.00e-03	26	53	2	DOID:1319 (implicated_via_orthology)
Disease	Glycogen Storage Disease	GYS1 GYS2	1.08e-03	27	53	2	C0017919
Disease	Pigmented Basal Cell Carcinoma	LATS1 SLC45A2	1.16e-03	28	53	2	C1368275
Disease	Carcinoma, Basal Cell	LATS1 SLC45A2	1.25e-03	29	53	2	C4721806
Disease	orofacial cleft	SEMA4D CADM1	2.03e-03	37	53	2	MONDO_0000358
Disease	suicide behaviour measurement	RANBP17 ARHGAP26	2.73e-03	43	53	2	EFO_0006882
Disease	thyroid peroxidase antibody measurement, anti-thyroglobulin antibody measurement	ANXA10 PDE10A	2.98e-03	45	53	2	EFO_0005666, EFO_0009896
Disease	fetal genotype effect measurement, body weights and measures	ARHGAP26 PDE10A	3.53e-03	49	53	2	EFO_0004324, EFO_0007959
Disease	cystic fibrosis (is_marker_for)	MUC5B MUC2	5.59e-03	62	53	2	DOID:1485 (is_marker_for)
Disease	C-reactive protein measurement	RANBP17 SEMA4D LATS1 LLGL1 GYS2 PDE10A ZFYVE1	5.59e-03	1206	53	7	EFO_0004458
Disease	cholangiocarcinoma (is_marker_for)	MUC5B MUC2	5.94e-03	64	53	2	DOID:4947 (is_marker_for)
Disease	carcinoma (implicated_via_orthology)	LATS1 LLGL1	5.94e-03	64	53	2	DOID:305 (implicated_via_orthology)
Disease	wheezing	PDE10A ZFYVE1	6.12e-03	65	53	2	EFO_0009715

Protein segments in the cluster

Peptide	Gene	Start	Entry
EKEERFAFGHHYFRP	ASH1L	2711	Q9NR48
FEFHHGDYEKQFLHV	C6orf62	146	Q9GZU0
SLFHDIRNFASGHYK	ANXA10	296	Q9UJ72
FGHFRLSSGKFYGHK	CALR3	46	Q96L12
KRFTDAGFDHHDLFF	CDC14B	271	O60729
GRYHGKFSFDTFSHH	ALDH3B1	411	P43353
LHHEYFTRDGFIEKF	CDKL3	281	Q8IVW4
KARIQDFVRGHFYGH	GYS2	301	P54840
DFVRGHFYGHLDFDL	GYS2	306	P54840
HLYDGFHGSIIFFDK	AADACL4	371	Q5VUY2
KRFTDAGFDHHDLFF	CDC14C	241	A4D256
GDFHYKTFDGDVFRF	MUC5B	81	Q9HC84
VSFGVFKLYGDNHFD	RANBP17	846	Q9H2T7
DLFCYGSHYFHKVAG	HPF1	296	Q9NWY4
LYFADTFLRDGAHHG	LLGL1	726	Q15334
KNGKHPEHAFYEFTF	LATS1	1066	O95835
SFGHKFNHRYGNLDG	MTMR7	376	Q9Y216
GFFGYVHFRQELNKS	LMAN1L	476	Q9HAT1
HALGFSAGLFAFYHD	LMLN	276	Q96KR4
GNFHYKTFDGDVFRF	MUC2	41	Q02817
DHRGFSNSYLQKFDH	PDE10A	556	Q9Y233
YDLFRNHHLASFGKV	PEX2	121	P28328
YGFHLHGEKGRRGQF	SLC9A3R2	21	Q15599
HNFLRGLHFHKDYFQ	PLA2G4B	571	P0C869
FKHNHGAYQFFREAL	NAA40	176	Q86UY6
GRYFARHKGTYFTHE	CADM1	396	Q9BY67
QYVAAGFERFHKLHY	DCDC2B	76	A2VCK2
HLDNGRGFGKYSHDE	FAM20C	476	Q8IXL6
HYHSFDGRKFDFQGT	FCGBP	2881	Q9Y6R7
PHYHSFDGRKFDFQG	FCGBP	4081	Q9Y6R7
QKHGNFKGFIDLHSY	CPA4	296	Q9UI42
DFHGHSRKNNIFLYG	AGBL2	556	Q5U5Z8
IFRKEPFFHGHDNYD	CSNK2A1	226	P68400
HFHYGRFQEFQKKSD	IFIT1	381	P09914
FHSRQYKHPDGFEGK	FMO2	171	Q99518
HSTHGGFLIRFYVKD	CRIPAK	421	Q8N1N5
KARIQEFVRGHFYGH	GYS1	301	P13807
EFVRGHFYGHLDFNL	GYS1	306	P13807
KYAGIFHFRFWHFGE	CAPN6	116	Q9Y6Q1
KEKGLHYHALFTGFG	SLC45A2	176	Q9UMX9
YSKGIFFHLLHFQLD	PKD1L1	351	Q8TDX9
GYIHRNFAGNRFSDH	DHX9	901	Q08211
YFRGHKEENGAAAHF	NR2E1	106	Q9Y466
VLFHSDGSKNFDGFH	PAMR1	216	Q6UXH9
GGHYFIDRDGKAFRH	KCTD11	21	Q693B1
FFPKTHREGDVHFDY	MMP11	181	P24347
FEGIYDHVGHFGRFQ	SLC22A16	6	Q86VW1
DHVGHFGRFQRVLYF	SLC22A16	11	Q86VW1
RHHYEMFTKFGDDGF	FAM20A	411	Q96MK3
GYYNGHTFHRIIKGF	PPWD1	526	Q96BP3
GLFTFYHHGYELAKD	ARHGAP26	206	Q9UNA1
EGKSQRSDHEFLFHY	STS	431	P08842
YRQHFFKHGGTAELK	SEMA4D	561	Q92854
FSLGFDVRDHYKDFG	CLUH	426	O75153
AFHHYFSKADHFRLG	CNOT11	91	Q9UKZ1
FHIDFGHILGNYKSF	PIK3CG	961	P48736
DYRDLFHRDFQFGHM	TMX3	276	Q96JJ7
FHRDFQFGHMDGNDY	TMX3	281	Q96JJ7
DGKSHTLNHTFFYGR	ZFYVE1	191	Q9HBF4
ECLEHRKDFGYHSAF	ZNF80	246	P51504
AHAGHYYSFIKDRRG	USP24	1966	Q9UPU5
KYHFRGHLGDQDFFT	XXYLT1	321	Q8NBI6